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Pre-Commercial Procurement framework and European funding sources for European Research Infrastructure Consortiums: Insights from the DiSSCo ERIC development 商业前采购框架和欧洲研究基础设施联盟的欧洲资金来源:来自DiSSCo ERIC发展的见解
Pub Date : 2023-10-13 DOI: 10.3897/rio.9.e113294
Gael Lymer, Frederik Leliaert, Patricia Mergen, Stefaan Pijls
Mechanisms and sources of funding for European Research Infrastructure Consortiums (ERICs) are diverse, complex and can be challenging to identify and to use. This paper provides a roadmap for Research & Development (R&D) within the pre-commercial procurement (PCP) framework and the landscape of funding for ERICs available from the European Union with a perspective on other tracks of funding. Our objective is to offer a starting point and underline opportunities and challenges, for existing and future ERICs. The work presented in this paper results from the research carried-out for the business model of the DiSSCo (Distributed System of Scientific Collections) ERIC, which is currently in its transition phase and will be constructed in the following years.
欧洲研究基础设施联盟(ERICs)的机制和资金来源是多样的、复杂的,并且很难识别和使用。本文为研究提供了路线图。商业前采购(PCP)框架内的开发(研发)和欧盟提供的ERICs资金前景,并从其他资金渠道的角度考虑。我们的目标是为现有和未来的ERICs提供一个起点,并强调机遇和挑战。本文所介绍的工作是对DiSSCo (Distributed System of Scientific Collections) ERIC商业模式进行研究的结果,该模式目前正处于过渡阶段,将在未来几年内建成。
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引用次数: 0
Global change in above-belowground multitrophic grassland communities 地下多营养化草地群落的全球变化
Pub Date : 2023-10-13 DOI: 10.3897/rio.9.e113960
Malte Jochum, Vera Zizka, Stefan Scheu, Nico Eisenhauer, Melanie Pollierer
Global change is transforming Earth’s ecological communities with severe consequences for the functions and services they provide. In temperate grasslands, home to a mesmerising diversity of invertebrates controlling multiple ecosystem processes and services, land-use intensification and climate change are two of the most important global-change drivers. While we know a lot about their independent effects on grassland biodiversity and ecosystem functioning, little is known about how these stressors interact. Moreover, most research on biodiversity change focuses on decreasing biomass or species richness, while a major aspect is commonly ignored – altered ecological interactions. This is problematic because these interactions represent and control many important ecosystem processes, such as predation, herbivory or decomposition. Networks of trophic interactions, so-called food webs, link the structure and functioning of ecological communities and unravel mechanistic relationships between environmental change, ecological communities and ecosystem multifunctionality – the ability of a system to simultaneously support multiple processes. Consequently, we need to study how ecological interactions and the food webs they comprise respond to environmental change and to multiple interacting global-change drivers. Fortunately, novel tools offer unprecedented opportunities in studying trophic interactions and their impact on ecosystem processes. In addition, we know far more about how global change impacts the aboveground world than its belowground counterpart. However, belowground communities are just as important for the overall functioning of terrestrial ecosystems. Thus, to comprehensively understand global-change impacts on temperate grasslands, we need to study above- and belowground multitrophic interactions and ecosystem processes together, also accounting for their interdependencies. Here, we propose to use the Global Change Experimental Facility (GCEF, Bad Lauchstädt, Germany) to study joint impacts of land-use intensity and climate change on above-belowground multitrophic interactions and ecosystem multifunctionality in a temperate grassland global-change experiment. We will combine novel approaches to assessing trophic interactions and basal-resource dependency with an innovative method to quantify energy flux through ecological interaction networks. We will disentangle separate and interactive effects of land use and climate change and unravel how global-change driven modifications in multitrophic interactions mechanistically translate into altered ecosystem processes and multifunctionality – above and below the ground. Combining a field-experimental approach with novel molecular and quantitative techniques will allow for a leap forward in our understanding of global-change impacts on temperate grasslands, which will be crucial to manage and conserve these important ecosystems.
全球变化正在改变地球上的生态群落,对它们提供的功能和服务造成严重后果。在温带草原,控制着多种生态系统过程和服务的无脊椎动物的多样性令人着迷,土地利用集约化和气候变化是两个最重要的全球变化驱动因素。虽然我们对它们对草地生物多样性和生态系统功能的独立影响了解很多,但对这些压力源如何相互作用知之甚少。此外,大多数关于生物多样性变化的研究都集中在生物量或物种丰富度的减少上,而一个重要的方面往往被忽视——生态相互作用的改变。这是有问题的,因为这些相互作用代表并控制着许多重要的生态系统过程,如捕食、食草或分解。营养相互作用网络,即所谓的食物网,将生态群落的结构和功能联系在一起,并揭示了环境变化、生态群落和生态系统多功能性(一个系统同时支持多个过程的能力)之间的机制关系。因此,我们需要研究生态相互作用及其组成的食物网如何响应环境变化和多种相互作用的全球变化驱动因素。幸运的是,新的工具为研究营养相互作用及其对生态系统过程的影响提供了前所未有的机会。此外,我们对全球变化如何影响地上世界的了解远远超过对地下世界的了解。然而,地下群落对陆地生态系统的整体功能同样重要。因此,为了全面了解全球变化对温带草原的影响,我们需要一起研究地上和地下的多营养相互作用和生态系统过程,并考虑它们的相互依赖性。本文建议利用全球变化实验设施(GCEF, Bad Lauchstädt, Germany),在温带草地全球变化实验中,研究土地利用强度和气候变化对地上-地下多营养相互作用和生态系统多功能性的共同影响。我们将结合评估营养相互作用和基础资源依赖的新方法,以及通过生态相互作用网络量化能量通量的创新方法。我们将解开土地利用和气候变化的单独和相互作用的影响,并揭示全球变化驱动的多营养相互作用的变化如何在机制上转化为改变的生态系统过程和多功能性-地上和地下。将实地实验方法与新颖的分子和定量技术相结合,将使我们对全球变化对温带草原影响的理解有一个飞跃,这对管理和保护这些重要的生态系统至关重要。
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引用次数: 0
DiSSCo Prepare Project: Increasing the Implementation Readiness Levels of the European Research Infrastructure DiSSCo准备项目:提高欧洲研究基础设施的实施准备水平
Pub Date : 2023-10-12 DOI: 10.3897/rio.9.e113906
Dimitrios Koureas, Laurence Livermore, Eva Alonso, Wouter Addink, Maria Judite Alves, Ana Casino, Luís Curral, Henrik Enghoff, Michel Guiraud, Helen Hardy, Jana Hoffmann, Salomé Landel, Carole Paleco, Mareike Petersen, Serge Scory, Vincent Smith, Claus Weiland, Karsten Wesche, Matt Woodburn
The Distributed System of Scientific Collections (DiSSCo) is a new world-class Research Infrastructure (RI) for Natural Science Collections. The DiSSCo RI aims to create a new business model for one European collection that digitally unifies all European natural science assets under common access, curation, policies and practices that ensure that all the data is easily Findable, Accessible, Interoperable and Reusable (FAIR principles). DiSSCo represents the largest ever formal agreement between natural history museums, botanic gardens and collection-holding institutions in the world. DiSSCo entered the European Roadmap for Research Infrastructures in 2018 and launched its main preparatory phase project (DiSSCo Prepare) in 2020. DiSSCo Prepare is the primary vehicle through which DiSSCo reaches the overall maturity necessary for its construction and eventual operation. DiSSCo Prepare raises DiSSCo’s implementation readiness level (IRL) across the five dimensions: technical, scientific, data, organisational and financial. Each dimension of implementation readiness is separately addressed by specific Work Packages (WP) with distinct targets, actions and tasks that will deliver DiSSCo’s Construction Masterplan. This comprehensive and integrated Masterplan will be the product of the outputs of all of its content related tasks and will be the project’s final output. It will serve as the blueprint for construction of the DiSSCo RI, including establishing it as a legal entity. DiSSCo Prepare builds on the successful completion of DiSSCo’s design study, ICEDIG and the outcomes of other DiSSCo-linked projects such as SYNTHESYS+ and MOBILISE. This paper is an abridged version of the original DiSSCo Prepare grant proposal. It contains the overarching scientific case for DiSSCo Prepare, alongside a description of our major activities.
分布式科学馆藏系统(DiSSCo)是一种新型的世界级自然科学馆藏研究基础设施(RI)。DiSSCo RI旨在为一个欧洲集合创建一个新的商业模式,该集合将所有欧洲自然科学资产在共同访问、管理、政策和实践下进行数字统一,以确保所有数据易于查找、访问、互操作和可重用(FAIR原则)。disco代表了世界上自然历史博物馆、植物园和收藏机构之间有史以来最大的正式协议。DiSSCo于2018年进入了欧洲研究基础设施路线图,并于2020年启动了其主要筹备阶段项目(DiSSCo Prepare)。DiSSCo Prepare是DiSSCo达到其建设和最终运营所需的整体成熟度的主要工具。DiSSCo Prepare提高了DiSSCo在五个方面的实施准备水平(IRL):技术、科学、数据、组织和财务。实施准备的每个维度都由具体的工作包(WP)单独处理,其中包含将交付disco建设总体规划的不同目标、行动和任务。这个全面和综合的总体规划将是其所有内容相关任务的产出的产物,并将是项目的最终产出。它将作为DiSSCo国际扶轮建设的蓝图,包括将其建立为一个法律实体。DiSSCo Prepare的基础是成功完成DiSSCo的设计研究、ICEDIG和其他与DiSSCo相关的项目(如SYNTHESYS+和MOBILISE)的成果。这篇论文是原始DiSSCo Prepare拨款提案的删节版。它包含了迪斯科准备的总体科学案例,以及我们主要活动的描述。
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引用次数: 1
Understanding the users and uses of UK Natural History Collections 了解英国自然历史馆藏的用户和用途
Pub Date : 2023-10-02 DOI: 10.3897/rio.9.e113378
Helen Hardy, Laurence Livermore, Paul Kersey, Ken Norris, Vincent Smith
UK natural science collections hold over 137 million items, an unrivalled source of data about 4.56 billion years of planetary development and hundreds of years of biological change, including the differences made by humans — but the scientific, commercial, and societal benefits of these collections are constrained by the limits of physical access, and by highly fragmented digitisation efforts with less than 10% digitally available. Following work with Frontier Economics in 2021, which showed potential for £2 billion in benefits to the UK economy from digitising all UK natural science collections, in 2022–23 the Natural History Museum London worked, with analytical support from McKinsey and Company, to understand the impact of what has already been digitised and shared by UK natural science collections — what is the demand for these data, what are they used for, and how does this deliver efficient, effective and impactful research? This study focuses on usage via the Global Biodiversity Information Facility, the largest source of relevant usage data, examining 7.6 million records from twelve UK institutions. While these UK collections data are just 0.3% of total GBIF occurrences, they are cited in 12% of peer reviewed publications citing GBIF data, showing the disproportionate impact of UK collections data and the historical, geographical, and taxonomic richness that they bring. Researchers have already benefited from more than £18 million of efficiency savings from digital UK specimen data. Data from natural science collections held in the UK are uniquely impactful resources, vital to a future in which people and planet thrive, and a step change in the pace of digitisation is needed to unlock their potential for researchers, policymakers, and society.
英国自然科学馆藏超过1.37亿件,是无与伦比的数据来源,涵盖了45.6亿年的地球发展和数百年的生物变化,包括人类造成的差异。但这些藏品的科学、商业和社会效益受到物理访问的限制,以及高度碎片化的数字化努力的限制,只有不到10%的数字可用。继2021年与Frontier Economics合作后,该研究表明,数字化所有英国自然科学藏品可能为英国经济带来20亿英镑的效益,2022-23年,伦敦自然历史博物馆在麦肯锡公司的分析支持下,开始了解英国自然科学藏品数字化和共享的影响对这些数据的需求是什么?它们的用途是什么?这些数据如何提供高效、有效和有影响力的研究?这项研究的重点是通过全球生物多样性信息设施的使用情况,这是相关使用数据的最大来源,检查了来自12个英国机构的760万条记录。虽然这些英国馆藏数据仅占GBIF总数的0.3%,但在引用GBIF数据的同行评议出版物中,它们被引用了12%,这表明英国馆藏数据及其带来的历史、地理和分类丰富性的不成比例的影响。研究人员已经从数字英国标本数据中节省了1800多万英镑的效率。英国自然科学馆藏的数据是具有独特影响力的资源,对人类和地球繁荣发展的未来至关重要,需要加快数字化步伐,为研究人员、政策制定者和社会释放它们的潜力。
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引用次数: 1
Assessing the FAIR Digital Object Framework for Global Biodiversity Research 全球生物多样性研究的FAIR数字目标框架评估
Pub Date : 2023-09-12 DOI: 10.3897/rio.9.e108808
Sharif Islam, James Beach, Elizabeth R. Ellwood, Jose Fortes, Larry Lannom, Gil Nelson, Beth Plale
In the first decades of the 21 st century, there has been a global trend towards digitisation and the mobilisation of data from natural history museums and research institutions. The development of national and international aggregator systems, which focused on data standards, made it possible to access millions of museum specimen records. These records serve as an empirical foundation for research across various fields. In addition, community efforts have expanded the concept of natural history collection specimens to include physical preparations and digital resources, resulting in the Digital Extended Specimen (DES), which also includes derived and related data. Within this context, the paper proposes using the FAIR Digital Object (FDO) framework to accelerate the global vision of the DES, arguing that FDO-enabled infrastructures can reduce barriers to the discovery and access of specimens, help ensure credit back to contributors and increase the amount of research that incorporates biodiversity data.
在21世纪的头几十年里,自然历史博物馆和研究机构的数据数字化和调动已经成为一种全球趋势。以数据标准为重点的国家和国际聚合系统的发展,使访问数百万个博物馆标本记录成为可能。这些记录为各个领域的研究提供了经验基础。此外,社区的努力扩大了自然历史收集标本的概念,包括物理准备和数字资源,从而产生了数字扩展标本(DES),其中还包括衍生和相关数据。在此背景下,本文建议使用FAIR数字对象(FDO)框架来加速DES的全球愿景,认为FDO支持的基础设施可以减少发现和获取标本的障碍,有助于确保将信用返还给贡献者,并增加纳入生物多样性数据的研究数量。
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引用次数: 0
FAIR Research Objects for realising Open Science with the EOSC project RELIANCE 利用EOSC项目RELIANCE实现开放科学的公平研究对象
Pub Date : 2023-09-05 DOI: 10.3897/rio.9.e108765
A. Fouilloux, Elisa Trasatti, Federica Foglini, Alejandro Coca-Castro, Jean Iaquinta
The numerous benefits of Open Science (OS) and of the four FAIR foundational principles - Findable, Accessible, Interoperable and Reusable - are increasingly valued in academia, although what OS and FAIR entail is still largely misunderstood. In such conditions, putting into practice OS and applying the FAIR principles is challenging and underrated. However, realising OS is perfectly within our grasp provided that an infrastructure supporting the management of the research lifecycle is available. ROHub (https://www.rohub.org/) is a Research Object (RO) management platform implementing three complementary technologies: Research Objects, Data Cubes and Text Mining services. ROHub enables researchers to collaboratively manage, share and preserve their research while they are still working on it (rather than after the work is finished). In this paper, three communities from Earth Sciences, namely Geohazards, Sea Monitoring and Climate Change, demonstrate how ROHub helped them to understand each other and to work openly and, more importantly, how communities of practice play an important role in facilitating reuse and interdisciplinary collaboration. These findings are illustrated with several use cases from these various communities.
开放科学(OS)和四个FAIR基本原则(可查找、可访问、可互操作和可重复使用)的众多好处在学术界越来越受到重视,尽管OS和FAIR所包含的内容仍在很大程度上被误解。在这种情况下,将OS付诸实践并应用FAIR原则是具有挑战性的,也是被低估的。然而,只要有支持研究生命周期管理的基础设施可用,我们就完全可以实现操作系统。ROHub(https://www.rohub.org/)是一个研究对象(RO)管理平台,实现了三种互补技术:研究对象、数据立方体和文本挖掘服务。ROHub使研究人员能够在研究期间(而不是在工作完成后)协同管理、共享和保存他们的研究。在这篇论文中,地球科学的三个社区,即地质灾害、海洋监测和气候变化,展示了ROHub如何帮助他们相互理解并公开工作,更重要的是,实践社区如何在促进再利用和跨学科合作方面发挥重要作用。这些发现通过来自这些不同社区的几个用例进行了说明。
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引用次数: 0
RIPARIANET - Prioritising riparian ecotones to sustain and connect multiple biodiversity and functional components in river networks RIPARIANET-优先考虑河岸交错带,以维持和连接河流网络中的多种生物多样性和功能组成部分
Pub Date : 2023-08-31 DOI: 10.3897/rio.9.e108807
Stefano Larsen, J. Álvarez‐Martínez, J. Barquín, M. Bruno, Laura Concostrina Zubiri, L. Gallitelli, M. Jonsson, Monika Laux, G. Pace, M. Scalici, R. Schulz
Europe has committed to upscale ecosystems protection to include 30% of land and sea. However, due to historical overexploitation of natural assets, the available area for biodiversity protection is severely limited. Riparian zones are natural ecotones between aquatic and terrestrial ecosystems, contributing disproportionately to regional biodiversity and providing multiple ecosystem functions and services. Due to this and their branching geometry, riparian networks form a vast system of ‘blue-green arteries’ which physically and functionally connect multiple ecosystems over elevation gradients, despite covering a relatively small area of the basin. Hence, RIPARIANET argues that developing approaches able to optimise the spatial conservation of natural stream-riparian networks represent a flagship example of biodiversity protection in the EU. Although the integrity of riparian zones is fundamental for the achievement of multiple EU environmental objectives, the lack of a standardised framework for biodiversity assessment and protection across Member States has led to extensive impairment of riparian areas and frequent stakeholder conflicts. The main objective of RIPARIANET is to leverage the increasing resolution of remote sensing information to provide practitioners with evidence-based guidance and approaches to biodiversity conservation. Key questions include: i) how can we remotely assess riparian integrity and identify areas which provide effective connectivity allowing species biodiversity and ecosystem functions to persist through meta-ecological processes? ii) how can we disentangle the influence of local- and network-scale stressors and processes on riparian biodiversity to better implement river basin management schemes? iii) to what extent do currently existing protected areas in rivers account for the geometry of riparian networks and their multifunctionality? We will address these questions in riparian networks within six river basins in Europe, including Boreal, Continental, Alpine, Temperate and Mediterranean systems. First, we will gather local needs and interests from key stakeholders together with satellite imagery and GIS environmental data for all basins. Then, riparian and river ecosystems functions will be modelled and ecological hotspots will be identified through a GIS-based multi-criteria approach, including stakeholder inputs. Then, we will collect in situ data to assess multiple biodiversity and stressors at the local scale and, subsequently, scale-up this information to the network scale using geostatistical tools and advanced modelling. This knowledge will be conveyed to managers at local and EU scales in the form of decision-support tools allowing decision-makers to identify protection gaps and ecological hotspots along riparian networks, based on multiple biodiversity, functional and connectivity criteria.
欧洲已承诺将生态系统保护范围扩大到30%的陆地和海洋。然而,由于历史上对自然资产的过度开发,可用于生物多样性保护的区域严重有限。河岸带是水生和陆地生态系统之间的自然交错带,对区域生物多样性的贡献不成比例,并提供多种生态系统功能和服务。由于这一点及其分支几何形状,河岸网络形成了一个庞大的“蓝绿色动脉”系统,尽管覆盖的流域面积相对较小,但这些动脉在物理和功能上通过海拔梯度连接了多个生态系统。因此,RIPARIANET认为,开发能够优化自然溪流河岸网络空间保护的方法是欧盟生物多样性保护的一个旗舰例子。尽管河岸带的完整性是实现欧盟多项环境目标的基础,但各成员国缺乏生物多样性评估和保护的标准化框架,导致河岸区受到广泛破坏,利益相关者冲突频繁。RIPARIANET的主要目标是利用遥感信息分辨率的提高,为从业者提供基于证据的生物多样性保护指导和方法。关键问题包括:i)我们如何远程评估河岸完整性,并确定能够提供有效连通性的区域,使物种生物多样性和生态系统功能通过元生态过程持续存在?ii)我们如何理清地方和网络规模的压力源和过程对河岸生物多样性的影响,以更好地实施流域管理计划?iii)目前河流中现有的保护区在多大程度上解释了河岸网络的几何形状及其多功能性?我们将在欧洲六个河流流域的河岸网络中解决这些问题,包括北方、大陆、阿尔卑斯、温带和地中海系统。首先,我们将收集主要利益攸关方的当地需求和利益,以及所有流域的卫星图像和GIS环境数据。然后,将对河岸和河流生态系统功能进行建模,并通过基于GIS的多标准方法(包括利益相关者的投入)确定生态热点。然后,我们将收集现场数据,以在当地范围内评估多种生物多样性和压力源,随后,使用地质统计学工具和高级建模将这些信息扩大到网络范围。这些知识将以决策支持工具的形式传达给地方和欧盟层面的管理者,使决策者能够根据多种生物多样性、功能和连通性标准,识别河岸网络沿线的保护差距和生态热点。
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引用次数: 0
How open science can support the 3Rs and improve animal research 开放科学如何支持3r并改善动物研究
Pub Date : 2023-08-31 DOI: 10.3897/rio.9.e105198
Monique R. E. Janssens, Stefan Gaillard, Judith de Haan, Wim de Leeuw, Matthew Brooke, Maura Burke, Jacques Flores, Iris Kruijen, Julia M L Menon, Adrian Smith, I. Tiebosch, F. Weijdema
Open science in its broadest sense can make better science and provide benefits to researchers. When applied to animal experimentation, it can prevent unnecessary use of animals, because knowledge and experiences about past animal experimentation are shared openly to be consulted and used by other researchers. By extension, open science can accelerate the much anticipated transition towards animal-free innovations or New Approach Methodologies (NAMs). The purpose of this paper is to bring together and further share the preparations and findings of a symposium held at Utrecht University on aspects of open science that researchers doing animal experiments can and should take into account to improve their research and benefit themselves. The paper offers a one-figure guideline for that purpose.
从广义上讲,开放科学可以创造更好的科学,并为研究人员提供好处。当应用于动物实验时,它可以防止不必要的动物使用,因为过去动物实验的知识和经验是公开分享的,供其他研究人员参考和使用。通过扩展,开放科学可以加速人们期待已久的向无动物创新或新方法方法论(NAMs)的过渡。本文的目的是汇集并进一步分享在乌得勒支大学举行的关于开放科学方面的研讨会的准备工作和发现,研究人员做动物实验可以而且应该考虑到这一点,以改进他们的研究并使自己受益。本文为此提供了一个一位数的指导方针。
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引用次数: 0
NFDI4Microbiota – national research data infrastructure for microbiota research NFDI4Microbiota -微生物群研究的国家研究数据基础设施
Pub Date : 2023-08-24 DOI: 10.3897/rio.9.e110501
Konrad U. Förstner, A. Becker, J. Blom, P. Bork, T. Clavel, M. Dieckmann, A. Goesmann, B. Götz, T. Gübitz, Franziska Hufsky, Sebastian Jünemann, Marie-Louise Körner, M. Marz, U. N. da Rocha, Jörg Overmann, A. Pühler, D. Rebholz-Schuhmann, A. Sczyrba, J. Stoye, Justine Vandendorpe, T. Van Rossum, A. Mchardy
Microbes – bacteria, archaea, unicellular eukaryotes, and viruses – play an important role in human and environmental health. Growing awareness of this fact has led to a huge increase in microbiological research and applications in a variety of fields. Driven by technological advances that allow high-throughput molecular characterization of microbial species and communities, microbiological research now offers unparalleled opportunities to address current and emerging needs. As well as helping to address global health threats such as antimicrobial resistance and viral pandemics, it also has a key role to play in areas such as agriculture, waste management, water treatment, ecosystems remediation, and the diagnosis, treatment and prevention of various diseases. Reflecting this broad potential, billions of euros have been invested in microbiota research programs worldwide. Though run independently, many of these projects are closely related. However, Germany currently has no infrastructure to connect such projects or even compare their results. Thus, the potential synergy of data and expertise is being squandered. The goal of the NFDI4Microbiota consortium is to serve and connect this broad and heterogeneous research community by elevating the availability and quality of research results through dedicated training, and by facilitating the generation, management, interpretation, sharing, and reuse of microbial data. In doing so, we will also foster interdisciplinary interactions between researchers. NFDI4Microbiota will achieve this by creating a German microbial research network through training and community-building activities, and by creating a cloud-based system that will make the storage, integration and analysis of microbial data, especially omics data, consistent, reproducible, and accessible across all areas of life sciences. In addition to increasing the quality of microbial research in Germany, our training program will support widespread and proper usage of these services. Through this dual emphasis on education and services, NFDI4Microbiota will ensure that microbial research in Germany is synergistic and efficient, and thus excellent. By creating a central resource for German microbial research, NDFDI4Microbiota will establish a connecting hub for all NFDI consortia that work with microbiological data, including GHGA, NFDI4Biodiversity, NFDI4Agri and several others. NFDI4Microbiota will provide non-microbial specialists from these consortia with direct and easy access to the necessary expertise and infrastructure in microbial research in order to facilitate their daily work and enhance their research. The links forged through NFDI4Microbiota will not only increase the synergy between NFDI consortia, but also elevate the overall quality and relevance of microbial research in Germany.
微生物——细菌、古菌、单细胞真核生物和病毒——在人类和环境健康中发挥着重要作用。对这一事实的日益认识导致微生物学研究和应用在各个领域的巨大增长。在允许对微生物物种和群落进行高通量分子表征的技术进步的推动下,微生物学研究现在为满足当前和新出现的需求提供了无与伦比的机会。除了帮助应对抗微生物耐药性和病毒大流行等全球健康威胁外,它还在农业、废物管理、水处理、生态系统修复以及各种疾病的诊断、治疗和预防等领域发挥着关键作用。反映出这种广泛的潜力,全球已在微生物群研究项目上投资数十亿欧元。尽管这些项目是独立运行的,但其中许多项目是密切相关的。然而,德国目前没有基础设施来连接这些项目,甚至没有比较它们的结果。因此,数据和专业知识的潜在协同作用正在被浪费。NFDI4微生物群联盟的目标是通过专门的培训提高研究结果的可用性和质量,并促进微生物数据的生成、管理、解释、共享和再利用,从而服务和连接这个广泛而异质的研究社区。通过这样做,我们还将促进研究人员之间的跨学科互动。NFDI4微生物群将通过培训和社区建设活动创建一个德国微生物研究网络,并创建一个基于云的系统,使微生物数据,特别是组学数据的存储、集成和分析在生命科学的所有领域保持一致、可复制和可访问,从而实现这一目标。除了提高德国微生物研究的质量外,我们的培训计划还将支持这些服务的广泛和正确使用。通过对教育和服务的双重重视,NFDI4微生物群将确保德国的微生物研究具有协同性和高效性,因此非常出色。通过为德国微生物研究创建一个中心资源,NDFDI4Microbiota将为所有从事微生物数据工作的NFDI联盟建立一个连接中心,包括GHGA、NFDI4Bioversity、NFDI4Agri和其他几个。NFDI4Microbiota将为这些联盟的非微生物专家提供直接和方便的微生物研究所需的专业知识和基础设施,以促进他们的日常工作并加强他们的研究。通过NFDI4微生物群建立的联系不仅将增加NFDI联盟之间的协同作用,还将提高德国微生物研究的整体质量和相关性。
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引用次数: 0
From implementation to application: FAIR digital objects for training data composition 从实现到应用:FAIR数字对象的训练数据组成
Pub Date : 2023-08-22 DOI: 10.3897/rio.9.e108706
Nicolas Blumenröhr, R. Aversa
Composing training data for Machine Learning applications can be laborious and time-consuming when done manually. The use of FAIR Digital Objects, in which the data is machine-interpretable and -actionable, makes it possible to automate and simplify this task. As an application case, we represented labeled Scanning Electron Microscopy images from different sources as FAIR Digital Objects to compose a training data set. In addition to some existing services included in our implementation (the Typed-PID Maker, the Handle Registry, and the ePIC Data Type Registry), we developed a Python client to automate the relabeling task. Our work provides a Proof-of-Concept validation for the usefulness of FAIR Digital Objects on a specific task, facilitating further developments and future extensions to other machine learning applications.
手动为机器学习应用程序编写训练数据可能既费力又耗时。FAIR数字对象的使用,其中的数据是机器可解释和可操作的,使得自动化和简化这项任务成为可能。作为一个应用案例,我们将来自不同来源的标记扫描电子显微镜图像表示为FAIR数字对象,以组成训练数据集。除了我们的实现中包含的一些现有服务(Typed PID Maker、Handle Registry和ePIC Data Type Registry)外,我们还开发了一个Python客户端来自动化重新标记任务。我们的工作为FAIR数字对象在特定任务中的有用性提供了概念验证,促进了其他机器学习应用程序的进一步开发和未来扩展。
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Research ideas and outcomes
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