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‘No-Option Chronic Limb-Threatening Ischaemia: What Can We Do To Save Limb? 无选择的慢性肢体威胁缺血性:我们能做些什么来拯救肢体?
Pub Date : 2023-01-01 DOI: 10.47829/cos.2023.9602
Florio A, Dennis Ms, Sallustro M
The aim of this study is to describe the characteristics, the management and the outcome of a series of patients with no-option critical limb ischemia (CLI) treated with a conservative multidisciplinary combined approach including best wound care, NPWT and dermal substitutes. The primary end was limb salvage and 1-year amputation-free survival. The secondary end was mortality and healing time of lesion. Between January 2016 and January 2021, 76 patients with no options CLI were admitted. In 14 patients, there was a failure in distal revascularization with a persistent CLI after the procedure. In 58 patients, revascularization was not feasible. Despite the persistent CLI, a group of patients of this cohort obtained no progression of CLI, complete wound healing treated with surgical debridement or distal amputation and application of NPWT in association with dermal substitute .Any superimposed infection was treated with antimicrobials. Pain was controlled with analgesics. Overall limb was saved in 72 % of the cases. A 1-year survival was 84%.Use of NPWT, dermal substitutes combined with a conservative foot surgery with an approach with minor amputation in patients with no-option CLI may save patient limb and life
本研究的目的是描述一系列无选择的严重肢体缺血(CLI)患者的特征、管理和结果,这些患者采用保守的多学科联合方法,包括最佳伤口护理、NPWT和真皮替代品。主要目的是肢体保留和1年无截肢生存。次要终点为病死率及病灶愈合时间。2016年1月至2021年1月期间,76名没有选择CLI的患者入院。在14例患者中,术后持续行CLI的远端血运重建术失败。58例患者血运重建术不可行。尽管持续的CLI,该队列中的一组患者没有出现CLI的进展,通过手术清创或远端截肢治疗伤口完全愈合,并使用NPWT联合皮肤替代品。任何合并感染均使用抗菌药物治疗。用镇痛药控制疼痛。72%的病例保留了整个肢体。1年生存率为84%。对于无选择的CLI患者,使用NPWT、真皮替代物联合保守足部手术和小截肢可以挽救患者的肢体和生命
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引用次数: 0
Treatment of Multifocal Neuroendocrine Tumor of the Ileum Whit Lymphatic Metastasis (NETG1) And Low Mutational Burden (TMB).Precision Surgery, Case Report and Review Literature 回肠白色淋巴转移多发神经内分泌肿瘤(NETG1)和低突变负担(TMB)的治疗。精确外科,病例报告和文献综述
Pub Date : 2023-01-01 DOI: 10.47829/cos.2023.9604
Losada J, Sarriugarte A, Irizar E, Maestro B, Urizar E, Losada I
SI-NETs: Small Intestinal Neuroendocrine Tumors; TMB: Tumor mutation burden; NET (G1): Grade 1; Mut/Mb: Total number of somatic/acquired mutations per coding area of a tumor genome; mCi: millicurium; TP53: cellular tumor antigen P53 (PTHR11447:SF6); RB1: Retinoblastoma associated protein (PTHR13742:SF17); CDKN1B: Cyclin dependent kinase inhibitor 1B (PTHR10265:SF9); KRAS: GTPase KRAS (PTHR24070:SF388); NRAS: GTPase NRAS (PTHR24070:SF189); MET: Hepatocyte growth factor receptor; HGNC: 7029
SI-NETs:小肠神经内分泌肿瘤;TMB:肿瘤突变负荷;NET (G1):一级;Mut/Mb:肿瘤基因组每个编码区的体细胞/获得性突变总数;mCi: millicurium;TP53:细胞肿瘤抗原P53 (PTHR11447:SF6);RB1:视网膜母细胞瘤相关蛋白(PTHR13742:SF17);CDKN1B: Cyclin依赖性激酶抑制剂1B (PTHR10265:SF9);KRAS: GTPase KRAS (PTHR24070:SF388);NRAS: GTPase NRAS (PTHR24070:SF189);MET:肝细胞生长因子受体;HGNC: 7029
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引用次数: 0
Assessment of Asian Pacific Screening Score for Risk Factor Stratification of Colorectal Cancer Patients: A Retrospective Audit from a Tertiary Care Institute, Pakistan 亚太地区结直肠癌患者危险因素分层筛查评分评估:来自巴基斯坦三级医疗机构的回顾性审计
Pub Date : 2023-01-01 DOI: 10.47829/cos.2023.9601
Khan MS, Hassan SR, Fatima G, Muhammad S, Sherazi B
clinicofsurgery.org 1
clinicofsurgery.org 1
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引用次数: 0
Perioperative Results of Open Renal Surgery in Patients with Dual Antiplatelet Therapy 双重抗血小板治疗的开放肾手术围手术期疗效观察
Pub Date : 2023-01-01 DOI: 10.47829/cos.2023.9203
Staehler M, Graser AK, Marcon J, Götz M, Ziegelmüller B, Rodler S
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引用次数: 0
Role of Cholecystostomy Drain in Severe Acute Cholecystitis in Critically Ill Patients 胆囊造瘘引流在重症急性胆囊炎患者中的作用
Pub Date : 2023-01-01 DOI: 10.47829/cos.2023.8701
M. B, Chauhan Mn, Nahboo Sz, Wilkinson E, Canelo R
Aims: To investigate the outcome of Cholecystostomy drains in the management of Acute Cholecystitis at Cumberland Infirmary. To develop a Cholecystostomy Pathway for patient selection, management and post procedure management. Method: A retrospective study of all patients with Cholecystostomy drains over the last 3 years at Cumberland Infirmary. 58 Inpatients at Cumberland Infirmary and West Cumberland Hospital who had cholecystostomy drains inserted for Acute Cholecystitis from January 2019 to January 2022 were included in the study. The patient list was collected from the Information Department at Cumberland Infirmary, with the Cholecystostomy code J 24.1 used in the search. Results: CRP ranged from 10-450 (mean 200) pre-insertion and on 5th post-procedure day, 37(63.79%) patients had a CRP of less than 50. Similar trends have been observed with the WBC counts. Follow-up investigations post drain insertion varied between CT abdomen, ultrasound abdomen and tubogram. The overall morality in the study group was 8(13.79%). Non of the mortalities were Cholecystostomy related. Reported over all complications were 2 (3.44%) which were sub-phrenic abscess and Cholo-Cutaneous fistula. Conclusion: We conclude that Insertion of a Cholecystostomy drain is a useful and safe procedure for the management of Severe Cholecystitis, especially in critically ill patients, with good early and late outcomes, and a low mortality rate. It can be used as a temporary management option with plan for Interval Laparoscopic Cholecystectomy, or can be the Definitive Management, especially in those patients with High Operative Risk
目的:探讨坎伯兰医院急性胆囊炎行胆囊造瘘引流的效果。为胆囊造瘘患者的选择、管理和术后管理制定胆囊造瘘路径。方法:回顾性分析坎伯兰医院近3年胆囊造瘘引流术患者,选取2019年1月至2022年1月在坎伯兰医院和西坎伯兰医院因急性胆囊炎行胆囊造瘘引流术的住院患者58例。患者名单从坎伯兰医院信息部收集,使用胆囊造瘘代码j24.1进行搜索。结果:插入前和术后第5天,CRP在10-450(平均200)之间,37例(63.79%)患者CRP低于50。白细胞计数也观察到类似的趋势。腹部CT、腹部超声和输卵管造影随访情况不同。研究组整体道德评分为8分(13.79%)。所有死亡病例均与胆囊造口术无关。其中膈下脓肿和胆皮瘘2例(3.44%)。结论:我们的结论是,置入胆囊造口引流管是治疗严重胆囊炎的一种有效且安全的方法,特别是在危重患者中,具有良好的早期和晚期预后,死亡率低。它可以作为间隔腹腔镜胆囊切除术计划的临时管理选择,也可以作为最终管理,特别是在那些手术风险高的患者中
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引用次数: 0
STARR Single Stapler? yes, we can. Starrone: Stapled Trans-Anal Rectal Resection with only one High-Volume Device. Review of 155 Personal Cases from 2009 to 2021 STARR单订书机?是的,我们可以。Starrone:只使用一个大容量装置的经肛直肠吻合器切除术。2009年至2021年155宗个案检讨
Pub Date : 2022-01-01 DOI: 10.47829/cos.2021.61401
Nando Gallese
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引用次数: 0
Ekos Thrombolysis for The Management of Ilio-Femoral Dvt at Cumberland Infirmary 坎伯兰医院Ekos溶栓治疗髂股静脉血栓
Pub Date : 2022-01-01 DOI: 10.47829/cos.2022.8503
M. B, N. I., Eifell R, Cusso M, Barakat T, Babikir S, Taran D, M. C., Ojimba T, Naqvi S
Introduction: Venous-thromboembolism is common vascular disease affecting lower limbs composed of DVT (2/3 of VTE) and PE (1/3 of VTE). The goal of management of DVT is to prevent PE, recurrence or PTS .Anticoagulation was the cornerstone of DVT management to prevent PE or recurrent DVT. Aim: To review our experience and assess efficacy of EKOS® thrombolysis in management of ilio-femoral DVT at Cumberland infirmary focusing on clinical outcome and any post procedure complications. Results: 22 patients had thrombolysis for illiofemoral DVT over 7years in Cumberland infirmary (Females 16 Males 5). Median age 20-89 years. Total number of treatment Sessions; 1 session: 18.18% (n=4), 2 Session: 54.54% (n=12), 3 sessions: 22.73% (n=5), 4 sessions: 04.55% (n=1). Success rate more than 80%: 90.91.7 % (n=20). Further procedures needed, Stents placement %77.27 (n=17), angioplasty 36.36% (n=8). Outcome; Improvement of symptoms in 90.91% % (n=20) leg ulcer healed in 9.52% (n=2). Post procedure complications: Leg swelling 28.6% (n=6) all are short terms resolved within six weeks and just one long standing leg swelling. Post procedure leg pain is in 19.04% (n=4). Ongoing issues were in 9.52% (n=2) and were persistent leg ulcer and PTS in each. One patient had recurrence. No patient had PE/ intracranial bleeding. Conclusion: EKOS is effective in treating acute ilio-femoral DVT with patency at 80% and more at the cessation of treatment, as well as prevention of DVT related long term complication (recurrence-PE and PTS) in comparison of conventional CDT or anticoagulation alone.
静脉血栓栓塞是影响下肢的常见血管疾病,由DVT(2/3的VTE)和PE(1/3的VTE)组成。DVT治疗的目标是预防PE、复发或PTS,抗凝治疗是预防PE或复发DVT治疗的基石。目的:回顾我们在Cumberland医院的经验,评估EKOS®溶栓治疗髂股深静脉血栓的疗效,重点关注临床结果和任何术后并发症。结果:在Cumberland医院,7年内有22例下肢深静脉血栓溶栓治疗(女16例,男5例),中位年龄20-89岁。治疗总次数;1次:18.18% (n=4), 2次:54.54% (n=12), 3次:22.73% (n=5), 4次:04.55% (n=1)。成功率大于80%:90.91.7% (n=20)。需要进一步手术的患者中,支架置入占77.27 (n=17),血管成形术占36.36% (n=8)。结果;症状改善者占90.91% (n=20),腿部溃疡愈合者占9.52% (n=2)。术后并发症:腿部肿胀28.6% (n=6)均为6周内短期消退,仅有一例长时间站立腿部肿胀。术后腿部疼痛发生率为19.04% (n=4)。9.52% (n=2)的患者存在持续性腿部溃疡和PTS问题。1例复发。无PE/颅内出血。结论:与常规CDT或单独抗凝相比,EKOS可有效治疗急性髂股DVT,停药时通畅率达80%以上,并可预防DVT相关的长期并发症(复发- pe和PTS)。
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引用次数: 0
Incisional Hernia Occurring after Ventriculoperitoneal Shunt Fixation 脑室腹腔分流器固定后发生的切口疝
Pub Date : 2022-01-01 DOI: 10.47829/cos.2022.8601
Alsharji M, Aljabri M, Elgohary H, Alhashmi M, Almuadi A
Ventriculo-peritoneal shunt is the procedure of choice for hydrocephalus. Various complications of ventriculoperitoneal shunts were reported. Abdominal complications involving the distal tip of the catheter make the majority of the complications. In this case report we present a case of incisional hernia occurring in a patient who underwent fixation of ventriculoperitoneal shunt followed by revision of the shunt after a while
脑室-腹膜分流术是脑积水的首选手术。报告了脑室-腹膜分流术的各种并发症。腹部并发症累及导管远端是并发症的主要原因。在这个病例报告中,我们提出了一个切口疝气的病例,发生在一个接受脑室-腹膜分流术固定的病人身上,一段时间后又对分流术进行了修正
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引用次数: 0
A Case of Superior Mesenteric Artery Occlusion without causing Non-Cirrhotic Portal Hypertension 肠系膜上动脉闭塞无肝硬化门静脉高压症1例
Pub Date : 2022-01-01 DOI: 10.47829/cos.2022.71001
Ekladious A, L. L
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引用次数: 0
Robotic Ileal Interposition Surgery with Duodenal Exclusion and Sleeve Gastrectomy For Diabetes: The First Case Report and 1-Year Follow-Up 机器人回肠介入手术联合十二指肠切除及袖式胃切除术治疗糖尿病:1例报告及1年随访
Pub Date : 2022-01-01 DOI: 10.47829/cos.2021.8502
Branco Filho AJ, C. Mrr, Brioschi Ml, Lavalle Acr
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引用次数: 0
期刊
Clinics of surgery
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