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The Impact of Cardiac-induced Post-traumatic Stress Disorder Symptoms on Cardiovascular Outcomes: Design and Rationale of the Prospective Observational Reactions to Acute Care and Hospitalizations (ReACH) Study. 心脏诱发的创伤后应激障碍症状对心血管结局的影响:急性护理和住院(ReACH)研究的前瞻性观察反应的设计和基本原理
Pub Date : 2019-01-01 Epub Date: 2019-01-14 DOI: 10.5334/hpb.16
Jeffrey Birk, Ian Kronish, Bernard Chang, Talea Cornelius, Marwah Abdalla, Joseph Schwartz, Joan Duer-Hefele, Alexandra Sullivan, Donald Edmondson

Aims: As many as 1 in 8 acute coronary syndrome (ACS) patients develop posttraumatic stress disorder (PTSD) due to the ACS, and ACS-induced PTSD may increase secondary cardiovascular disease (CVD) risk. However, prior studies have been small and underpowered to test plausible behavioral or biological mechanisms of the hypothesized PTSD-secondary CVD risk association. In this paper, we describe the design and methods of a large prospective observational cohort study to estimate the prognostic significance of ACS-induced PTSD, mechanisms for its association with CVD risk, and emergency department (ED) factors that may increase PTSD risk, in a cohort of patients evaluated for acute coronary syndrome (ACS) in the ED of a large, urban academic medical center.

Methods: The Reactions to Acute Care and Hospitalization (ReACH) study follows 1,741 racially, ethnically, and socioeconomically diverse patients initially presenting to the ED with ACS symptoms. Psychosocial factors are assessed at baseline. Medication adherence is monitored by electronic pill bottle (eCAP). Participants are contacted by phone at 1-, 6-, and 12-months post-hospitalization to assess PTSD symptoms, hospital readmission, and recurrent CVD events/mortality (proactively searched and confirmed by medical records).

Conclusion: This study will provide the most accurate estimates to date of PTSD's association with recurrent CVD events and mortality and will test whether medication adherence mediates that association. Further, it will provide estimates of the contribution of ED and hospital factors to PTSD risk in ACS patients. If our hypotheses are supported, we will have identified PTSD as a novel target for secondary risk reduction.

目的:每8例急性冠脉综合征(ACS)患者中就有1例发生创伤后应激障碍(PTSD), ACS诱发的PTSD可能增加继发性心血管疾病(CVD)的风险。然而,先前的研究规模较小,不足以测试假设的ptsd -继发性心血管疾病风险关联的合理行为或生物学机制。在本文中,我们描述了一项大型前瞻性观察队列研究的设计和方法,以估计ACS诱导的PTSD的预后意义,其与CVD风险的关联机制,以及可能增加PTSD风险的急诊科(ED)因素,在一个大型城市学术医疗中心的急诊科评估急性冠脉综合征(ACS)的患者队列。方法:对急性护理和住院的反应(ReACH)研究随访了1741例最初以急性冠脉综合征症状就诊的不同种族、民族和社会经济背景的患者。在基线时评估心理社会因素。通过电子药瓶(eCAP)监测药物依从性。在住院后1个月、6个月和12个月通过电话联系参与者,以评估PTSD症状、再入院和复发性心血管疾病事件/死亡率(通过医疗记录主动搜索和确认)。结论:这项研究将提供迄今为止最准确的PTSD与复发性心血管疾病事件和死亡率的关联,并将测试药物依从性是否介导这种关联。此外,它将提供ED和医院因素对ACS患者PTSD风险的贡献的估计。如果我们的假设得到支持,我们将确定PTSD作为降低继发性风险的新目标。
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引用次数: 14
Development of a Smoke-Free Homes Intervention for Parents: An Intervention Mapping Approach. 为家长制定无烟家庭干预措施:干预映射法。
Pub Date : 2019-01-01 Epub Date: 2019-12-19 DOI: 10.5334/hpb.20
Rachel O'Donnell, Ruaraidh Dobson, Marijn de Bruin, Stephen Turner, Lorna Booth, Sean Semple

Exposure to second-hand smoke (SHS) is associated with various ill-health outcomes for children and adults. Barriers to creating a smoke-free home (SFH) are well-documented. Feasible and effective interventions to create smoke-free homes for disadvantaged households are lacking. Interventions that include providing parents with objective information about the impact of smoking on air quality in their home may be particularly effective. This study describes the development of a novel, theory- and evidence-based smoke-free homes intervention using objectively-assessed air quality feedback. The intervention was developed using the six-step Intervention Mapping (IM) protocol. Findings from literature reviews, focus groups with parents, interviews with health/care professionals, and expert panel discussions shaped intervention content and materials. Findings highlighted the importance of parents receiving personalised information on second-hand smoke levels in their home. Professionals considered the use of non-judgemental language essential in developed materials. Previous literature highlighted the need to address home smoking behaviour at a household rather than individual level. The AFRESH intervention is modular and designed to be delivered face-to-face by healthcare professionals. It includes up to five meetings with parents, two sets of five days' air quality monitoring and personalised feedback, and the option to involve other household members in creating a smoke-free home using educational, motivational, and goal setting techniques. Further research is needed to evaluate the acceptability and effectiveness of the AFRESH intervention and which specific groups of parents this intervention will most likely benefit. IM was a useful framework for developing this complex intervention. This paper does not present evaluation findings.

接触二手烟(SHS)与儿童和成人的各种健康不良后果有关。创建无烟家庭(SFH)的障碍已得到充分证实。目前还缺乏可行且有效的干预措施来为弱势家庭创建无烟家庭。为家长提供有关吸烟对家庭空气质量影响的客观信息,可能是特别有效的干预措施。本研究介绍了一种新颖的、以理论和证据为基础的无烟家庭干预措施的发展情况,该干预措施使用了客观评估的空气质量反馈信息。该干预措施采用了六步干预绘图(IM)协议。文献综述、与家长的焦点小组讨论、与健康/护理专业人员的访谈以及专家小组讨论的结果决定了干预的内容和材料。调查结果强调了家长获得有关其家中二手烟水平的个性化信息的重要性。专业人士认为,在编写的材料中使用非评判性语言至关重要。以往的文献强调,需要从家庭而非个人层面解决家庭吸烟行为问题。AFRESH 干预方案采用模块化设计,由医疗保健专业人员面对面提供。它包括与家长的多达五次会面、两套为期五天的空气质量监测和个性化反馈,以及利用教育、激励和目标设定技术让其他家庭成员参与创建无烟家庭的选项。还需要进一步的研究来评估 AFRESH 干预措施的可接受性和有效性,以及该干预措施最有可能惠及哪些特定的家长群体。IM 是制定这一复杂干预措施的有用框架。本文不提供评估结果。
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引用次数: 0
Testing the Effectiveness of a Short-Term Stress Prevention Programme in Primary School Students 测试小学生短期压力预防计划的成效
Pub Date : 2018-07-13 DOI: 10.5334/HPB.11
C. Englert, Aline Bechler, Sarah Singh, Alex Bertrams
The present study tested the effectiveness of a four-week, school-based, universal cognitive-behavioural stress prevention programme. The prevention programme included short daily exercises which were adopted from two well-validated anti stress trainings. The daily exercises took approximately 10−15 minutes on average and were performed during regular classroom sessions. Half of the classes were randomly assigned to the prevention group (n = 80), while the other half were sorted into the non-treatment control group, which did not take part in the stress prevention programme (n = 73). The students’ physical and psychological stress-related symptoms were assessed five times (i.e., prior to the training and after each week of training). Their coping strategies, self-efficacy and self-control were also measured. It was hypothesized that in the prevention group students’ physical and psychological stress-related symptoms would significantly decrease over time, compared to the non-treatment control group. Contrary to our predictions, the prevention programme did not lead to statistically significant changes in physical or psychological stress-related symptoms. The students’ coping strategies, self-efficacy and self-control did not have an influence on the result patterns. The results indicate that short-term stress prevention programmes may not be as effective as long-term programmes.
本研究测试了为期四周、以学校为基础的普遍认知行为压力预防计划的有效性。预防方案包括从两次经过充分验证的抗压力培训中采用的短期日常锻炼。每天的练习平均耗时约10-15分钟,在常规课堂上进行。一半的班级被随机分配到预防组(n=80),而另一半则被分到不参加压力预防计划的非治疗对照组(n=73)。对学生的身体和心理压力相关症状进行了五次评估(即在训练前和每周训练后)。他们的应对策略、自我效能感和自制力也被测量。据推测,与非治疗对照组相比,预防组学生的身体和心理压力相关症状会随着时间的推移显著减少。与我们的预测相反,预防计划并没有导致身体或心理压力相关症状的统计显著变化。学生的应对策略、自我效能和自我控制对结果模式没有影响。结果表明,短期压力预防方案可能不如长期方案有效。
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引用次数: 2
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Health psychology bulletin
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