Bulletin de la Societe de pathologie exotique et de ses filiales最新文献

Since unsafe water elicits a broad spectrum of bacteriological, parasitological and virological diseases, purification of polluted drinking water has to be developed in tropical rural regions. Around 70% of rural wells and 7% of bore-holes contain water unsafe for human consumption. Water is also contaminated during transport and storage. Several techniques of purification have been recommended to protect drinking water. Recently, sterilisation in the U. V. or simply in the sun rays has been systematically tested. In tropical rural areas, solar disinfection has given questionable results. It affords no guarantee for the health of the consumer in contrast with other techniques as chlorination.

Forty carriers of 20 or more W. bancrofti var. pacifica per ml were blind administered ivermectin at 50, 100, 150 or 200 mcg/kg doses. The rate of successful treatment was 100% with the 4 dosages. The percentage cure rate and the decrease percentage in the microfilarial count were significantly higher in persons treated with 100, 150 and 200 mcg/kg than in persons treated with 50 mcg/kg. Frequency and intensity of side-reactions were similar to those observed during treatment with DEC; they were more frequent and severe in persons with greatest microfilaremia but did not depend on the dosage. Ivermectin in 100 mcg/kg single-dose, administered once a year, is the best candidate to replace DEC in mass treatments.

880 suspect sera were analysed for HIV2 antibodies (ELISA, Western Blot) during the 2nd and 3rd trimester of 1988. Results show that Kinshasa is not yet an endemic zone for this virus. The authors recommend the use of a mixed test for diagnostics.

Are presented in this study results on the Sionas-Secoyas' subsistence pattern and health and nutrition status. Sionas-Secoyas still preserved a traditional way of life despite considerable demographic and environmental changes in the province. They are entirely self sufficient. The degree to which they meet their energy requirements appeared to be low but their intakes are obviously underestimated due to an important extra-household food consumption. Protein intakes are high; consumption of foods of animal origin is important. The quality of their alimentation is reasonably good. There are no cases of undernutrition; children growth is steady despite their smallness; they have a robust physical constitution. Parasitic burden is not heavy compared with other surveys in Amazonia. Infectious diseases are not frequent too. However this very propice situation is jeopardized by the process of agricultural development and the unceasing trespassing of the reservation boundaries. State officials should pay more attention to the preservation of Sionas-Secoyas' interests and must protect them from the covetousness of outsiders.

Authors searched by mean of radio-immuno-essay A and C anti-meningococcal antibodies in two villages from Niger (181 and 92 patients) in a meningitidis endemic area, which one profited 10 months ago of a mass vaccination campaign (A and C polysaccharides). A and C antibodies quantities and percentages of protected patients are not significantly different between the two villages. In one hand anti-C levels increase with patients age. In the other hand, there is a correlation between C meningococcal antibodies and anti-Hbc antibodies.

In complement to a previous survey, the authors proceed to the analysis of strains isolated from visceral human and canine leishmaniasis. Finally, among eight human strains isolated and identified with an enzymatic method, seven belong to the Leishmania donovani complex and one to the L. infantum complex. The L. donovani complex is represented by the MON-31 and MON-83 zymodem. The first one is also present in Saudi Arabia and Ethiopia. The second one, corresponding to a small variant, pleads for an intrafocal polymorphism phenomenon which was until now unknown in the L. donovani complex. The L. infantum complex is observed: 1) in sympatria with L. donovani in mountainous areas; 2) alone in the Tihama coastal plain. As for human cutaneous leishmaniasis present in the same focuses it is caused by L. tropica MON-71 and not by the above mentioned complexes.

Enterotoxigenic Escherichia coli (ETEC) of infant origin from the Popular Democratic Republic Lao were characterized with respect to there 0 serogroups, biotypes, anti-bioresistances, fimbrial antigens and types of enterotoxins produced. Enterotoxin production was determined by the suckling mice assay, competitive GM1-erythroassay, and cell cultures (CHOK1 and Y1). The presence of genes encoding for the enterotoxins was determined by colony hybridization by using radioactive DNA probes. Profile plasmids from ETEC strains were studied. The plasmids encoding for heat-labile enterotoxin were studied with an acetyl-aminofluorene modified probe.

Polyacrylamide gel electrophoresis allowing study of rotavirus genome was applied to 213 faecal specimens from children with acute gastroenteritis living in Dakar area, Senegal. We were able to define an electrophoretype in 41 cases (19.2%). Five different RNA electrophoretypes were shown. The electrophoretype 4 was the most frequent (41.4%). "Long" and "short" electrophoretic migration patterns were found in 36 and 5 cases, respectively. We found 34.1% of electrophoretypes in children aged from 6 to 11 months. The electrophoretypes 1, 3, 4 and 5 have co-circulated throughout the study period (March 1985 to August 1986). No mixed infections were found. Large surveys of this type would allow to evaluate the general situation in Senegal in urban areas as well as in rural areas.

A new case of cutaneous Leishmaniasis to L. braziliensis Vianna, 1911, contracted in French Guyana is reported. The parasite, isolated in culture, is identified by enzymatic typing (13 zymoden). The identified zymodem is zymodem MON-43. It is the same of the WHO reference strain L. braziliensis s. st.