Pub Date : 2021-08-30DOI: 10.34297/ajbsr.2021.14.001951
Daniela A Gutiérrez
The COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). SARS-CoV-2 spike proteins target the angiotensin-converting enzyme 2 (ACE2) receptors localized mainly in the lungs. Recent studies have shown that SARS-CoV-2 also targets the CNS neurons and glial cells, triggering a cytokine immune-inflammatory response, compromising the blood-brain barrier, and ultimately causing neuronal death [1,2]. Thus, neurological diseases like Alzheimer’s disease (AD) are a particular comorbidity for COVID-19.
{"title":"The ACE2 COVID-19 target in Alzheimer’s disease","authors":"Daniela A Gutiérrez","doi":"10.34297/ajbsr.2021.14.001951","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001951","url":null,"abstract":"The COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). SARS-CoV-2 spike proteins target the angiotensin-converting enzyme 2 (ACE2) receptors localized mainly in the lungs. Recent studies have shown that SARS-CoV-2 also targets the CNS neurons and glial cells, triggering a cytokine immune-inflammatory response, compromising the blood-brain barrier, and ultimately causing neuronal death [1,2]. Thus, neurological diseases like Alzheimer’s disease (AD) are a particular comorbidity for COVID-19.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44681194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-30DOI: 10.34297/ajbsr.2021.14.001948
Z. Wang
To study the effect of restriction of unilateral movement of the first metatarsophalangeal joint (FMJ) on the biomechanics and gait of the contralateral lower limb. 8 adult college students completed walking with barefoot and left foot FMJ constraint (FMJC) respectively. The time node for collecting gait and biomechanical parameters is (I) 0min barefoot walking, (II) Walk immediately with FMJC at 0min, (III) walk after 30min with FMJC, (IV) walk barefoot after 30min with FMJC; Calculate the gait parameters on the contralateral side of the FMJC, the net joint torque and the joint moment arms of the hip, knee and ankle joints. Compared with the time node I, the maximum dorsiflexion angle and the maximum plantar flexion angle of the unrestricted side ankle joint at time node III increased significantly (p<0.05), and the maximum plantar flexion moment and maximum dorsiflexion moment increased significantly (p<0.05), the power of the ankle joint increased significantly (p<0.05); the torque and power of the hip and knee joints on the unrestricted side increased significantly (p<0.05); On the unrestricted side, there was no significant difference in stride length, swing phase, support phase and step length (p>0.05). Short-term unilateral FMJC will cause biomechanical compensation and compensation transmission in the unrestricted lower limb joints. That is, the unrestricted hip, knee, and ankle joints maintain normal gait by strengthening their work, and the transmission of compensation is enhanced from top to bottom.
{"title":"The Influence of Short-term Restriction of Unilateral First Metatarsophalangeal Joint on the Contralateral Lower Limb Joints","authors":"Z. Wang","doi":"10.34297/ajbsr.2021.14.001948","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001948","url":null,"abstract":"To study the effect of restriction of unilateral movement of the first metatarsophalangeal joint (FMJ) on the biomechanics and gait of the contralateral lower limb. 8 adult college students completed walking with barefoot and left foot FMJ constraint (FMJC) respectively. The time node for collecting gait and biomechanical parameters is (I) 0min barefoot walking, (II) Walk immediately with FMJC at 0min, (III) walk after 30min with FMJC, (IV) walk barefoot after 30min with FMJC; Calculate the gait parameters on the contralateral side of the FMJC, the net joint torque and the joint moment arms of the hip, knee and ankle joints. Compared with the time node I, the maximum dorsiflexion angle and the maximum plantar flexion angle of the unrestricted side ankle joint at time node III increased significantly (p<0.05), and the maximum plantar flexion moment and maximum dorsiflexion moment increased significantly (p<0.05), the power of the ankle joint increased significantly (p<0.05); the torque and power of the hip and knee joints on the unrestricted side increased significantly (p<0.05); On the unrestricted side, there was no significant difference in stride length, swing phase, support phase and step length (p>0.05). Short-term unilateral FMJC will cause biomechanical compensation and compensation transmission in the unrestricted lower limb joints. That is, the unrestricted hip, knee, and ankle joints maintain normal gait by strengthening their work, and the transmission of compensation is enhanced from top to bottom.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43905409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-30DOI: 10.34297/ajbsr.2021.14.001947
R. Zibaseresht
One-Pot Efficient Synthesis of 1,4-Bis (2,2′:6′,2′′-Terpyridin-4′-Yl) Benzene Ditopic Bridging Ligand. Abstract The ditopic bridging 1,4-bis(2,2′:6′,2′′-terpyridin-4′-yl) benzene (I) was prepared in a controlled one-pot condensation reaction of acetylpyri - dine, benzene-1,4-dicarbaldehyde and ammonium acetate in basic medium in EtOH in high yield. The product was characterised using conventional methods.
{"title":"One-Pot Efficient Synthesis of 1,4-Bis (2,2′:6′,2′′-Terpyridin-4′-Yl) Benzene Ditopic Bridging Ligand","authors":"R. Zibaseresht","doi":"10.34297/ajbsr.2021.14.001947","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001947","url":null,"abstract":"One-Pot Efficient Synthesis of 1,4-Bis (2,2′:6′,2′′-Terpyridin-4′-Yl) Benzene Ditopic Bridging Ligand. Abstract The ditopic bridging 1,4-bis(2,2′:6′,2′′-terpyridin-4′-yl) benzene (I) was prepared in a controlled one-pot condensation reaction of acetylpyri - dine, benzene-1,4-dicarbaldehyde and ammonium acetate in basic medium in EtOH in high yield. The product was characterised using conventional methods.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42165151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-30DOI: 10.34297/ajbsr.2021.14.001953
A. Kashif
Objective: To evaluate the coagulation profile in COVID-19 patients and to correlate disease severity with the coagulation parameters. Methodology: This retrospective study was conducted at Pathology and medicine departments, FMH College of Medicine and Dentistry. It included 101 confirmed cases of COVID-19 disease of both genders between 17 and 75-year age. Coagulation profile was compared between survivor and non-survivor groups. Results: Out of 101 patients, 93 (92.1%) patients were in the survivor group and eight (7.8%) in the non-survivor group. Mean APTT (p = 0.02) in non-survivor group showed relatively higher values than survivor group. Mean D-Dimers (p = 0.007) in non-survivors showed a significantly raised values. However other parameters of coagulation like Platelets, MPV, PT and INR showed no significant association statistically. Conclusion: High D-dimers and prolonged APTT were associated with mortality in COVID-19 Patients.
{"title":"Coagulation Profile In COVID-19","authors":"A. Kashif","doi":"10.34297/ajbsr.2021.14.001953","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001953","url":null,"abstract":"Objective: To evaluate the coagulation profile in COVID-19 patients and to correlate disease severity with the coagulation parameters. Methodology: This retrospective study was conducted at Pathology and medicine departments, FMH College of Medicine and Dentistry. It included 101 confirmed cases of COVID-19 disease of both genders between 17 and 75-year age. Coagulation profile was compared between survivor and non-survivor groups. Results: Out of 101 patients, 93 (92.1%) patients were in the survivor group and eight (7.8%) in the non-survivor group. Mean APTT (p = 0.02) in non-survivor group showed relatively higher values than survivor group. Mean D-Dimers (p = 0.007) in non-survivors showed a significantly raised values. However other parameters of coagulation like Platelets, MPV, PT and INR showed no significant association statistically. Conclusion: High D-dimers and prolonged APTT were associated with mortality in COVID-19 Patients.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41332168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-27DOI: 10.34297/ajbsr.2021.14.001945
N. Khan
Nanotheranostics is a novel yet developing field which promises advanced methods for clinical diagnostics and treatment. Certain biological molecules present inside human body and their varying concentrations are used as detectable signals for nanoparticles or nanoconjugates to identify cancerous or tumors cells and also targeting these effected cells for the treatment of disease. At present, available treatments are expensive, time consuming with potential side effects. Therefore, application of nanotheranostics will surely help to minimize such issues and promises better therapeutics in nanomedicine
{"title":"Nanotheranostics-An Emerging Technique in Nanomedicine","authors":"N. Khan","doi":"10.34297/ajbsr.2021.14.001945","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001945","url":null,"abstract":"Nanotheranostics is a novel yet developing field which promises advanced methods for clinical diagnostics and treatment. Certain biological molecules present inside human body and their varying concentrations are used as detectable signals for nanoparticles or nanoconjugates to identify cancerous or tumors cells and also targeting these effected cells for the treatment of disease. At present, available treatments are expensive, time consuming with potential side effects. Therefore, application of nanotheranostics will surely help to minimize such issues and promises better therapeutics in nanomedicine","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43390252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-27DOI: 10.34297/ajbsr.2021.14.001946
Fahri Ozsungur
The aim of this study is to present a management approach to transforming the deficiencies in crisis management during the pandemic period into a strong facet of businesses. In this research, phenomenology and grounded theory were adopted. The results of the study revealed five basic principles in the form of quantum management of hospital management: Infinity of possibilities, resilience to waves of uncertainty and making sense, the complementarity of diversity and complexity, significance of chaos and crisis, interactive outputs. These basic principles are under the influence of three basic factors based on medical, administrative, sharing-interaction.
{"title":"Quantum Management of Hospital in the Post-COVID-19","authors":"Fahri Ozsungur","doi":"10.34297/ajbsr.2021.14.001946","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001946","url":null,"abstract":"The aim of this study is to present a management approach to transforming the deficiencies in crisis management during the pandemic period into a strong facet of businesses. In this research, phenomenology and grounded theory were adopted. The results of the study revealed five basic principles in the form of quantum management of hospital management: Infinity of possibilities, resilience to waves of uncertainty and making sense, the complementarity of diversity and complexity, significance of chaos and crisis, interactive outputs. These basic principles are under the influence of three basic factors based on medical, administrative, sharing-interaction.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44168288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-26DOI: 10.34297/ajbsr.2021.14.001944
D. Ayim-Aboagye
Sweden continues to enjoy the elderly and psychiatric healthcare in its welfare state. This development could not have been successful without the hard work of biomedical scientists and their researchers. We investigate in this study the involvement of biomedical research, its personnel and the way it has championed new knowledge and confidence in the industries as a whole. Moreover, the psychiatric work in prison institutions is investigated to find out how inmates are being helped by these professionals to deal with their guilt.
{"title":"The Swedish Elderly and Psychiatric Healthcare as Models: An Investigation into the Social Importance of Healthcare and Biomedical Science Research","authors":"D. Ayim-Aboagye","doi":"10.34297/ajbsr.2021.14.001944","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001944","url":null,"abstract":"Sweden continues to enjoy the elderly and psychiatric healthcare in its welfare state. This development could not have been successful without the hard work of biomedical scientists and their researchers. We investigate in this study the involvement of biomedical research, its personnel and the way it has championed new knowledge and confidence in the industries as a whole. Moreover, the psychiatric work in prison institutions is investigated to find out how inmates are being helped by these professionals to deal with their guilt.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42501892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-25DOI: 10.34297/ajbsr.2021.14.001942
Mohammad Noori
Total knee arthroplasty (TKA) has become one of the most common operations in all of medicine, with an average of 966,000 performed annu - ally in the United States. Since its introduction in 1968, TKA surgical techniques and implant designs have improved to increase prosthesis longevity. However, aseptic loosening of TKA components continues to be the most common reason for revision surgery. Ideal implant characteristics, which minimize stress shielding have yet to be determined. The purpose of this study was to investigate how implant design parameters including fixation technique, tibial stem geometry, cement stiffness, and implant-bone frictional interface affect stress shielding within the tibia, and to determine the optimal combination that minimizes this effect. A CT scan of a tibia was used to simulate multiple tibial stem configurations for finite element analysis in ABAQUS. Stress shielding was calculated by using the average minimum principal stress at interval cuts along the length of the tibia. We found that short, fully-cemented stems, high-stiffness hybrid cemented stems, low-stiffness for fully-cemented stems, and a sliding friction interface to be ideal.
{"title":"Finite Element Analysis of Total Knee Arthroplasty","authors":"Mohammad Noori","doi":"10.34297/ajbsr.2021.14.001942","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001942","url":null,"abstract":"Total knee arthroplasty (TKA) has become one of the most common operations in all of medicine, with an average of 966,000 performed annu - ally in the United States. Since its introduction in 1968, TKA surgical techniques and implant designs have improved to increase prosthesis longevity. However, aseptic loosening of TKA components continues to be the most common reason for revision surgery. Ideal implant characteristics, which minimize stress shielding have yet to be determined. The purpose of this study was to investigate how implant design parameters including fixation technique, tibial stem geometry, cement stiffness, and implant-bone frictional interface affect stress shielding within the tibia, and to determine the optimal combination that minimizes this effect. A CT scan of a tibia was used to simulate multiple tibial stem configurations for finite element analysis in ABAQUS. Stress shielding was calculated by using the average minimum principal stress at interval cuts along the length of the tibia. We found that short, fully-cemented stems, high-stiffness hybrid cemented stems, low-stiffness for fully-cemented stems, and a sliding friction interface to be ideal.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46745794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-25DOI: 10.34297/ajbsr.2021.14.001941
Sara Am
Background: Antibiotics residue in food from animal origin represents a public health issue concerns the authorities worldwide. Method: 100 egg samples were collected from Khartoum state’s markets to evaluate the current situation of oxy tetracycline residue. briefly, Samples were homogenized, weighed (2 g); and processed by adding citric acid (100 mg), 30% nitric acid (1 ml), methanol (4 ml) followed by adding 1 ml of deionized water; then centrifuged at 5300 for 10 mints followed by filtration throughout 0.22 µm syringe filter and 20 µl of the sample was injected into HPLC equipped with UV-VIS detector and ODS (C-18) column and read at 360 nm. Result: 49 % of total samples were positive. 48% of those positive samples (24 out of 49); were equal or exceeded the MRL of Oxytetracycline in egg (200 ppb). The mean values obtained from the three different state’s cities were not significantly different between different localities, never theless between each city and the MRL the variance was vastly significant.
{"title":"Assessment of Oxytetracycline Residue in Table Eggs from Khartoum State’s Markets","authors":"Sara Am","doi":"10.34297/ajbsr.2021.14.001941","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.14.001941","url":null,"abstract":"Background: Antibiotics residue in food from animal origin represents a public health issue concerns the authorities worldwide. Method: 100 egg samples were collected from Khartoum state’s markets to evaluate the current situation of oxy tetracycline residue. briefly, Samples were homogenized, weighed (2 g); and processed by adding citric acid (100 mg), 30% nitric acid (1 ml), methanol (4 ml) followed by adding 1 ml of deionized water; then centrifuged at 5300 for 10 mints followed by filtration throughout 0.22 µm syringe filter and 20 µl of the sample was injected into HPLC equipped with UV-VIS detector and ODS (C-18) column and read at 360 nm. Result: 49 % of total samples were positive. 48% of those positive samples (24 out of 49); were equal or exceeded the MRL of Oxytetracycline in egg (200 ppb). The mean values obtained from the three different state’s cities were not significantly different between different localities, never theless between each city and the MRL the variance was vastly significant.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45774944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-24DOI: 10.34297/ajbsr.2021.13.001938
Ana María Valencia Castaño
Clostridium difficile is a gram-positive rod responsible for the majority of hospital-acquired gastrointestinal infections in humans. Recently in the world literature an exponential increase in its incidence has been reported, involving new more virulent strains that affect new groups of patients that were previously unaffected, generating a series of changes in the clinical presentation of the disease and in the treatment, which influ- ences the prognosis of the disease in these patients. An early diagnosis is essential for therapeutic management and for the implementation of con-tainment measures. However, the speed with which new strains with greater pathogenicity are developed is higher than that with which new drugs are developed to combat them, all this as a result of the irrational use of antibiotics that alter the pathogenicity mechanism of this type of bacteria. In this article we review the pathophysiological aspects of C. difficile infection associated with dysbiosis caused by the use of antibacterials, with the aim of contributing to the preparation of general practitioners and specialists to provide timely and quality care to those who receive it. suffer from this disease and make a more rational use of antibiotics.
{"title":"Clostridium Difficile Pathogenicity Mechanism Associated with Dysbiosis Caused by The Use of Antibacterials","authors":"Ana María Valencia Castaño","doi":"10.34297/ajbsr.2021.13.001938","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001938","url":null,"abstract":"Clostridium difficile is a gram-positive rod responsible for the majority of hospital-acquired gastrointestinal infections in humans. Recently in the world literature an exponential increase in its incidence has been reported, involving new more virulent strains that affect new groups of patients that were previously unaffected, generating a series of changes in the clinical presentation of the disease and in the treatment, which influ- ences the prognosis of the disease in these patients. An early diagnosis is essential for therapeutic management and for the implementation of con-tainment measures. However, the speed with which new strains with greater pathogenicity are developed is higher than that with which new drugs are developed to combat them, all this as a result of the irrational use of antibiotics that alter the pathogenicity mechanism of this type of bacteria. In this article we review the pathophysiological aspects of C. difficile infection associated with dysbiosis caused by the use of antibacterials, with the aim of contributing to the preparation of general practitioners and specialists to provide timely and quality care to those who receive it. suffer from this disease and make a more rational use of antibiotics.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43577584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}