Pub Date : 2019-08-07DOI: 10.24966/tcr-3735/100010
E. Semu
{"title":"Heavy Metals and Organopesticides: Ecotoxicology, Health Effects and Mitigation Options with Emphasis on Sub-Saharan Africa","authors":"E. Semu","doi":"10.24966/tcr-3735/100010","DOIUrl":"https://doi.org/10.24966/tcr-3735/100010","url":null,"abstract":"","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73739222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-07DOI: 10.24966/tcr-3735/100006
F. Najari
Background Lead poisoning is one of the most important problems worldwide, caused by occupational poisoning and opioid addiction. Materials and methods This descriptive, analytical, cross-sectional study was performed among patients with lead poisoning, who were referred to Baqiyatallah Hospital of Tehran, Iran during 2016-2017. Results The study population consisted of 200 patients, including 32 females (14%) and 168 males (86%), who were referred to the Poisoning Department of Baqiyatallah Hospital during 2016-2017. The blood lead level of patients ranged from 9μg/dL to 180μg/dL. Overall, 18% of patients suffered from muscular weakness (peripheral neuropathy), and 95% had a history of oral opioid use. Conclusion Based on the findings, lead poisoning should be taken into account in opioid addicts, experiencing abdominal pain and constipation. Considering the high rate of poisoning following the oral use of opioids, it is recommended to refer addicts to addiction treatment clinics and provide them with psychiatric counseling. Citation: Mesri M, Valizadegan G, Najari F, Baradaran I, Najari D (2019) Investigation of the Clinical Signs and Symptoms of Lead Poisoning in Patients Referred to Baqiyatallah Hospital, Tehran, Iran in 2016-2017. J Toxicol Cur Res 3: 006.
背景:由职业中毒和阿片类药物成瘾引起的铅中毒是全球最重要的问题之一。材料与方法本研究对2016-2017年伊朗德黑兰Baqiyatallah医院转诊的铅中毒患者进行了描述性、分析性、横断面研究。结果2016-2017年转诊至巴基亚塔拉医院中毒科的200例患者，其中女性32例(14%)，男性168例(86%)。患者血铅水平为9 ~ 180μg/dL。总体而言，18%的患者患有肌肉无力(周围神经病变)，95%的患者有口服阿片类药物的使用史。结论阿片类药物依赖者出现腹痛和便秘时应考虑铅中毒。考虑到口服阿片类药物后中毒发生率高，建议将成瘾者转介到成瘾治疗诊所，并为其提供心理咨询。引用本文:Mesri M, Valizadegan G, Najari F, Baradaran I, Najari D(2019) 2016-2017年伊朗德黑兰Baqiyatallah医院转诊患者铅中毒临床体征和症状调查。[J]中国生物医学工程学报，2003,19(4):326 - 326。
{"title":"Investigation of the Clinical Signs and Symptoms of Lead Poisoning in Patients Referred to Baqiyatallah Hospital, Tehran, Iran in 2016-2017","authors":"F. Najari","doi":"10.24966/tcr-3735/100006","DOIUrl":"https://doi.org/10.24966/tcr-3735/100006","url":null,"abstract":"Background Lead poisoning is one of the most important problems worldwide, caused by occupational poisoning and opioid addiction. Materials and methods This descriptive, analytical, cross-sectional study was performed among patients with lead poisoning, who were referred to Baqiyatallah Hospital of Tehran, Iran during 2016-2017. Results The study population consisted of 200 patients, including 32 females (14%) and 168 males (86%), who were referred to the Poisoning Department of Baqiyatallah Hospital during 2016-2017. The blood lead level of patients ranged from 9μg/dL to 180μg/dL. Overall, 18% of patients suffered from muscular weakness (peripheral neuropathy), and 95% had a history of oral opioid use. Conclusion Based on the findings, lead poisoning should be taken into account in opioid addicts, experiencing abdominal pain and constipation. Considering the high rate of poisoning following the oral use of opioids, it is recommended to refer addicts to addiction treatment clinics and provide them with psychiatric counseling. Citation: Mesri M, Valizadegan G, Najari F, Baradaran I, Najari D (2019) Investigation of the Clinical Signs and Symptoms of Lead Poisoning in Patients Referred to Baqiyatallah Hospital, Tehran, Iran in 2016-2017. J Toxicol Cur Res 3: 006.","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90634466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-07DOI: 10.24966/tcr-3735/100009
F. Busico, Istituto Zooprofilattico Sperimentale delle regioni Lazio e “M.Aleandri”
Direct or indirect prolonged exposure to organic contaminants diffused into the environment may lead to chronic toxicity through human milk. Infants and young children exposure during breast feeding can have a negative impact on adulthood. For this reason, some scientists express reservations on the benefits of lactation, despite the World Health Organization (WHO) and the American Academy of Pediatrics (AAP) continue to recommend breastfeeding. However, the human milk is the best way to monitor the level of exposure of these substances in the environment and in the food. This study studied the levels of Polychlorinated Dibenzodioxins, Polychlorinated Dibenzofurans (PCDD/F) and Polychlorinated Biphenyls (PCBs) in human milk in the Italian region of Lazio, which includes the provinces of Rome, Rieti, Viterbo, Latina, Frosinone, and correlated them with eating habits and residence of the donor mothers. We found no difference in Dioxins and PCB levels in human milk among the provinces of Lazio, with the exception of Rome, and no relationship between the levels of contamination detected in the milk and eating habits, confirming previously published literature. The levels of PCDD/F were compared with data obtained in other European countries between 1998 and 2015. We found a reduction of POPs in human milk compared to what has been detected in recent years in Italy and in other European countries and we conclude that the strict rules and the official controls in order to restrain the diffusion of those substances into the environment and into human food are gradually getting good results.
{"title":"Monitoring of Persistent Organic Pollutants in Human Milk of Lazio Region","authors":"F. Busico, Istituto Zooprofilattico Sperimentale delle regioni Lazio e “M.Aleandri”","doi":"10.24966/tcr-3735/100009","DOIUrl":"https://doi.org/10.24966/tcr-3735/100009","url":null,"abstract":"Direct or indirect prolonged exposure to organic contaminants diffused into the environment may lead to chronic toxicity through human milk. Infants and young children exposure during breast feeding can have a negative impact on adulthood. For this reason, some scientists express reservations on the benefits of lactation, despite the World Health Organization (WHO) and the American Academy of Pediatrics (AAP) continue to recommend breastfeeding. However, the human milk is the best way to monitor the level of exposure of these substances in the environment and in the food. This study studied the levels of Polychlorinated Dibenzodioxins, Polychlorinated Dibenzofurans (PCDD/F) and Polychlorinated Biphenyls (PCBs) in human milk in the Italian region of Lazio, which includes the provinces of Rome, Rieti, Viterbo, Latina, Frosinone, and correlated them with eating habits and residence of the donor mothers. We found no difference in Dioxins and PCB levels in human milk among the provinces of Lazio, with the exception of Rome, and no relationship between the levels of contamination detected in the milk and eating habits, confirming previously published literature. The levels of PCDD/F were compared with data obtained in other European countries between 1998 and 2015. We found a reduction of POPs in human milk compared to what has been detected in recent years in Italy and in other European countries and we conclude that the strict rules and the official controls in order to restrain the diffusion of those substances into the environment and into human food are gradually getting good results.","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"139 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79913808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-07DOI: 10.24966/tcr-3735/100008
Mohamed Hr
The purpose of this work was to determine the concentration and risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in cold-smoked mullet fish samples which were pre-frozen at -18°C for 6 months. Fish samples were obtained from two fish farms; A (Al-Batts drain) and B (El-Wadi drain), El-Fayoum governorate, Egypt. 16 components of PAHs concentration were determined by GC-MS. Results showed that the total concentration of PAHs recorded16.2 and 7.4 ppb sample of Aand B-smoked mullet fish products, respectively. Also, levels of Benzo [a] Pyrene (B {a} P) equivalent were 0.0378 and 0.029 ppb in A and B-products, respectively. Besides, content of Low molecular weight (LMW) components was higher in A-smoked mullet product than medium MW and vice versa in case B-smoked product however, high MW was not detected in products. In conclusion, PAHs concentration in smoked products processed from pre-frozen mullet samples for 6 months at -18°C are considered a minimally contaminated (16.2 ppb) for A-smoked product and not contaminated (7.4 ppb) for B-smoked product compared with recommended levels. In addition to the component of Benzo [a] Pyrene (B {a} P) was not detectable in all smoked fish products.
{"title":"Risk Assessment of Polycyclic Aromatic Hydrocarbons concentration in Cold Smoked Mullet Fish (Mugil Cephalus)","authors":"Mohamed Hr","doi":"10.24966/tcr-3735/100008","DOIUrl":"https://doi.org/10.24966/tcr-3735/100008","url":null,"abstract":"The purpose of this work was to determine the concentration and risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in cold-smoked mullet fish samples which were pre-frozen at -18°C for 6 months. Fish samples were obtained from two fish farms; A (Al-Batts drain) and B (El-Wadi drain), El-Fayoum governorate, Egypt. 16 components of PAHs concentration were determined by GC-MS. Results showed that the total concentration of PAHs recorded16.2 and 7.4 ppb sample of Aand B-smoked mullet fish products, respectively. Also, levels of Benzo [a] Pyrene (B {a} P) equivalent were 0.0378 and 0.029 ppb in A and B-products, respectively. Besides, content of Low molecular weight (LMW) components was higher in A-smoked mullet product than medium MW and vice versa in case B-smoked product however, high MW was not detected in products. In conclusion, PAHs concentration in smoked products processed from pre-frozen mullet samples for 6 months at -18°C are considered a minimally contaminated (16.2 ppb) for A-smoked product and not contaminated (7.4 ppb) for B-smoked product compared with recommended levels. In addition to the component of Benzo [a] Pyrene (B {a} P) was not detectable in all smoked fish products.","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86366301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-25DOI: 10.24966/tcr-3735/100003
Graciela Inés Santillán
{"title":"Toxocariasis in Two Ecosystems in Argentina","authors":"Graciela Inés Santillán","doi":"10.24966/tcr-3735/100003","DOIUrl":"https://doi.org/10.24966/tcr-3735/100003","url":null,"abstract":"","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88339962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-25DOI: 10.24966/tcr-3735/100004
Gregorio Martínez Sánchez
{"title":"Hair Analysis by Polarized Light Microscopy, a New Tool in Medical Research","authors":"Gregorio Martínez Sánchez","doi":"10.24966/tcr-3735/100004","DOIUrl":"https://doi.org/10.24966/tcr-3735/100004","url":null,"abstract":"","PeriodicalId":93103,"journal":{"name":"HSOA journal of toxicology : current research","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91040253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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