{"title":"A commentary on rehabilitation effect of Liuzijue in water on patients with chronic obstructive pulmonary disease in stable period","authors":"Wang Zhenwei","doi":"10.15761/mri.1000158","DOIUrl":"https://doi.org/10.15761/mri.1000158","url":null,"abstract":"","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: August 24, 2019; Accepted: September 20, 2019; Published: September 23, 2019 According to SEER database, more than 3 million women live with breast cancer worldwide. A recent statistical analysis evaluated the incidence and prevalence of breast cancer in Lebanese women, and revealed that it was the most prevalent cancer in Lebanon, accounting for 20% of all cancer cases, among the highest in the world. The average age-standardized incidence rate over 11 years (2005-2015) was 96.5 per 100,000, with a significantly increasing trend over time [1]. The adherence to the most recent guidelines in the treatment of breast cancer in the Lebanese population is a must, in order to obtain the best outcomes in terms of remission and survival.
{"title":"The updated use of dual HER2 blockade in breast cancer therapy: a project of an institutional experience","authors":"C. Georges, Moujaess Elissar","doi":"10.15761/mri.1000164","DOIUrl":"https://doi.org/10.15761/mri.1000164","url":null,"abstract":"Received: August 24, 2019; Accepted: September 20, 2019; Published: September 23, 2019 According to SEER database, more than 3 million women live with breast cancer worldwide. A recent statistical analysis evaluated the incidence and prevalence of breast cancer in Lebanese women, and revealed that it was the most prevalent cancer in Lebanon, accounting for 20% of all cancer cases, among the highest in the world. The average age-standardized incidence rate over 11 years (2005-2015) was 96.5 per 100,000, with a significantly increasing trend over time [1]. The adherence to the most recent guidelines in the treatment of breast cancer in the Lebanese population is a must, in order to obtain the best outcomes in terms of remission and survival.","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wen-Hung Wang, Max R. Chang Ishcol, Chih-Yen Lin, Sheng-Fan Wang
{"title":"Galectins participate in virus infection, friend or foe?","authors":"Wen-Hung Wang, Max R. Chang Ishcol, Chih-Yen Lin, Sheng-Fan Wang","doi":"10.15761/mri.1000154","DOIUrl":"https://doi.org/10.15761/mri.1000154","url":null,"abstract":"","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: The aim of this clinical study was to evaluate ceramic laminate veneers constructed from Lithium disilicate (IPS e.max CAD), and resin nano-ceramic (Lava UltimateTM CAD/CAM) according to the modified United States of Public Health Service (USPHS) criteria over 12 months. Materials and methods: Twenty-eight ceramic laminate veneers (fourteen for each group) were placed in the Fixed Prosthodontics Department clinics, Faculty of Dentistry, Cairo University by one operator. The restorations were made using CEREC premium 4.4 CAD/CAM software with IPS e.max CAD and Lava UltimateTM CAD/CAM blocks. Modified USPHS criteria were used to evaluate the clinical performance of the restorations. Patient satisfaction were assessed using visual analogue scale. Fisher’s Exact test was used to compare between the two groups. Friedman’s test was used to study the changes by time in each group. Patient satisfaction scores (VAS scores) were presented as median and range values. Results: Regrading marginal adaptation, retention, and fracture, through the whole study period; all restorations in the two groups showed (Alpha) scores. While for marginal discoloration, all surfaces of restorations in the two groups showed (Alpha) scores till 6 months. While after 8, 10 and 12 months; the palatal surface of Lava Ultimate group showed (Bravo) scores. However, there was no statistically significant difference between the two groups after 12 months (P-value = 0.481). The overall satisfaction of restorations was very satisfied by 85.7% and satisfied by 14.3%. Conclusion: Both IPS e.max CAD and Lava Ultimate laminate veneers revealed high successful clinical performance over a period of 12 months follow up. *Correspondence to: Mai M ElGendi, Dentist at ministry of health, Cairo, Egypt, E-mail: mai.eltohami@dentistry.cu.edu.eg
{"title":"One-year clinical evaluation of e.max CAD and LavaTM ultimate laminate veneers with butt joint preparation (Randomized controlled clinical trial)","authors":"Mai Elgendi, Karim Rabie, A. Zaki","doi":"10.15761/mri.1000160","DOIUrl":"https://doi.org/10.15761/mri.1000160","url":null,"abstract":"Purpose: The aim of this clinical study was to evaluate ceramic laminate veneers constructed from Lithium disilicate (IPS e.max CAD), and resin nano-ceramic (Lava UltimateTM CAD/CAM) according to the modified United States of Public Health Service (USPHS) criteria over 12 months. Materials and methods: Twenty-eight ceramic laminate veneers (fourteen for each group) were placed in the Fixed Prosthodontics Department clinics, Faculty of Dentistry, Cairo University by one operator. The restorations were made using CEREC premium 4.4 CAD/CAM software with IPS e.max CAD and Lava UltimateTM CAD/CAM blocks. Modified USPHS criteria were used to evaluate the clinical performance of the restorations. Patient satisfaction were assessed using visual analogue scale. Fisher’s Exact test was used to compare between the two groups. Friedman’s test was used to study the changes by time in each group. Patient satisfaction scores (VAS scores) were presented as median and range values. Results: Regrading marginal adaptation, retention, and fracture, through the whole study period; all restorations in the two groups showed (Alpha) scores. While for marginal discoloration, all surfaces of restorations in the two groups showed (Alpha) scores till 6 months. While after 8, 10 and 12 months; the palatal surface of Lava Ultimate group showed (Bravo) scores. However, there was no statistically significant difference between the two groups after 12 months (P-value = 0.481). The overall satisfaction of restorations was very satisfied by 85.7% and satisfied by 14.3%. Conclusion: Both IPS e.max CAD and Lava Ultimate laminate veneers revealed high successful clinical performance over a period of 12 months follow up. *Correspondence to: Mai M ElGendi, Dentist at ministry of health, Cairo, Egypt, E-mail: mai.eltohami@dentistry.cu.edu.eg","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) shows growing tendency across the world, thus requiring the convenient mice models mimic the pathology and pathogenesis of human disease to accelerate the findings of this disease. Herein, we summarized the mice model of NAFLD-HCC recently developed. *Correspondence to: Jin Yang, Translational Medicine Center, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, 310015, China, E-mail: hz_zhiy@163.com
{"title":"Mice models of NAFLD-related HCC","authors":"Anna Chen, A. Lu, Jin Yang","doi":"10.15761/mri.1000162","DOIUrl":"https://doi.org/10.15761/mri.1000162","url":null,"abstract":"Nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) shows growing tendency across the world, thus requiring the convenient mice models mimic the pathology and pathogenesis of human disease to accelerate the findings of this disease. Herein, we summarized the mice model of NAFLD-HCC recently developed. *Correspondence to: Jin Yang, Translational Medicine Center, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, 310015, China, E-mail: hz_zhiy@163.com","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seasonal asthma/ post viral asthma produces epidemic like condition in developed and developing countries which causes a huge burden to the society socially as well as economically with an increase in morbidity and mortality. This review highlights the preventive steps in controlling seasonal asthma symptoms. *Correspondence to: Tarun Saxena, Department of Internal Medicine, Mittal Hospital and Research Centre, Ajmer, Rajasthan, India, Tel: +91-9829089284, E-mail: yogdiab@gmail.com/info@mittalhospital.com Received: June 07, 2019; Accepted: June 21, 2019; Published: June 24, 2019 Introduction The worldwide incidences of bronchial asthma are increasing. The correlation between metabolism (basal metabolic rate/BMR) and asthma treatment is less clear in the literature due to the presence of multiple risk factors in the causation of asthma. Seasonal variations are also reported in both BMR and asthma [1-7]. Methods Various studies have been used to review the process [1-16]. Results: Studies describe that metabolism changes with environmental temperature and season. It is also found that the asthma epidemic occurs during the change of season i.e. winter to summer, maximum attack rate during spring; and summer to winter, maximum attack rate during autumn/pre-winter. A clear association of asthma exacerbation and exposure to environmental air temperature is found. If environmental temperature opposes existing metabolism e.g. rise in temperature during spring tries to reduce BMR opposite to high BMR of winters and conversely in autumn low BMR of summer is opposed by mild cool air in pre winter. This alteration exacerbates asthma symptoms. In winter and spring, the metabolism remains high and asthma symptoms respond well to substances which increase the metabolic rate, such as clove. In summer and autumn, the metabolism remains low and asthma symptoms respond well to substances which reduce the metabolic rate, like rose petal jam [1,2,3,7]. Conclusion The possible mechanism by which change in metabolism affects inflammation in the tracheobronchial tree seems to involve the respiratory tract, as one of the sites of heat and water release and thermoregulation in the body. During Winter/spring there is a high metabolic state which causes heat preservation in the body along with the respiratory tract. When there is an increase in temperature or any viral exposure then it opposes the existing metabolism of the body which leads to heat or water release in the body as well as in the respiratory tract in the form of inflammation in the respiratory tract with exacerbation of asthmatic symptoms. When such patients are administered hot substances like clove which has properties to increase the body metabolism will revert to its previous metabolism. Thus there will be heat preservation in the body and respiratory tract and decrease in inflammation in the respiratory tract and this, in turn, will help to reduce the symptoms of asthma. During Summer/Autumn there is a l
季节性哮喘/病毒性哮喘在发达国家和发展中国家都产生类似流行病的状况，给社会、社会和经济造成巨大负担，发病率和死亡率不断上升。这篇综述强调了控制季节性哮喘症状的预防措施。*通信:Tarun Saxena，内科，米塔尔医院和研究中心，Ajmer，拉贾斯坦邦，印度，电话:+91-9829089284,E-mail: yogdiab@gmail.com/info@mittalhospital.com录用日期:2019年6月21日;简介全球支气管哮喘的发病率正在上升。代谢(基础代谢率/BMR)与哮喘治疗之间的相关性在文献中不太清楚，因为哮喘的病因存在多种危险因素。BMR和哮喘也有季节性变化的报道[1-7]。方法多种研究对该过程进行了回顾[1-16]。结果:研究描述了代谢随环境温度和季节的变化。哮喘流行有季节变化特征，冬夏交替，春季发病率最高;从夏季到冬季，在秋季/冬前发作率最高。发现哮喘加重与暴露于环境空气温度有明显关联。如果环境温度与现有的代谢相反，例如春季温度升高会降低BMR，与冬季高BMR相反，秋季反之，夏季低BMR则与冬前温和的冷空气相对立。这种改变加剧了哮喘症状。在冬季和春季，新陈代谢仍然很高，哮喘症状对增加代谢率的物质反应良好，如丁香。在夏秋两季，代谢水平较低，哮喘症状对降低代谢率的物质反应良好，如玫瑰花瓣果酱[1,2,3,7]。结论代谢变化影响气管支气管树炎症的可能机制可能与呼吸道有关，呼吸道是机体热、水释放和体温调节的部位之一。在冬季和春季，人体处于高代谢状态，导致身体和呼吸道的保温。当温度升高或任何病毒暴露时，它就会阻碍身体现有的新陈代谢，从而导致身体和呼吸道中的热量或水分释放，以呼吸道炎症的形式出现，哮喘症状加剧。当这样的病人服用热的物质，如丁香，具有增加身体新陈代谢的特性，将恢复到以前的新陈代谢。因此，身体和呼吸道会有保温，呼吸道炎症会减少，反过来，这将有助于减轻哮喘的症状。在夏季和秋季，人体处于低代谢状态，导致身体和呼吸道释放热量和水分。当环境温度降低或任何病毒暴露时，它就会阻碍身体现有的新陈代谢从而导致热量或水分在体内和呼吸道中被保存以呼吸道炎症的形式出现哮喘症状加剧。当这些病人服用具有降低身体新陈代谢特性的冷却物质，如玫瑰花瓣果酱，会恢复到以前的新陈代谢。因此，身体和呼吸道会释放热量或水分，从而减少呼吸道的炎症，从而有助于减轻哮喘的症状。呼吸道病毒通过呼吸道进入人体，但进入血液后产生发热并影响中枢水平(下丘脑)的体温调节机制。预防措施/临床意义夏季/秋季哮喘发作的注意事项:在日常饮食中加入各种冷却物质，如时令水果、时令蔬菜、甘露、酪乳、玫瑰花瓣果酱、小豆蔻。Saxena T(2019)哮喘治疗与季节性代谢变化的关系vol . 3: 2-2 Med Res Innov, 2019 doi: 10.15761/MRI。1000159 2。从4月到10月，哮喘患者应该定期在清晨散步，这有助于身体适应凉爽的空气，有助于防止冬季哮喘发作。3.哮喘患者应该在早晨在户外、屋顶和花园做瑜伽/运动，以发展对环境的适应和增加肺活量。4. 在夏季的病毒性哮喘症状中，对身体有凉爽作用/降低BMR的中枢作用物质，如香旋花或假马齿苋，是有用的。须知1。 季节性哮喘/病毒性哮喘在发达国家和发展中国家都产生类似流行病的状况，给社会、社会和经济造成巨大负担，发病率和死亡率不断上升。这篇综述强调了控制季节性哮喘症状的预防措施。*通信:Tarun Saxena，内科，米塔尔医院和研究中心，Ajmer，拉贾斯坦邦，印度，电话:+91-9829089284,E-mail: yogdiab@gmail.com/info@mittalhospital.com录用日期:2019年6月21日;简介全球支气管哮喘的发病率正在上升。代谢(基础代谢率/BMR)与哮喘治疗之间的相关性在文献中不太清楚，因为哮喘的病因存在多种危险因素。BMR和哮喘也有季节性变化的报道[1-7]。方法多种研究对该过程进行了回顾[1-16]。结果:研究描述了代谢随环境温度和季节的变化。哮喘流行有季节变化特征，冬夏交替，春季发病率最高;从夏季到冬季，在秋季/冬前发作率最高。发现哮喘加重与暴露于环境空气温度有明显关联。如果环境温度与现有的代谢相反，例如春季温度升高会降低BMR，与冬季高BMR相反，秋季反之，夏季低BMR则与冬前温和的冷空气相对立。这种改变加剧了哮喘症状。在冬季和春季，新陈代谢仍然很高，哮喘症状对增加代谢率的物质反应良好，如丁香。在夏秋两季，代谢水平较低，哮喘症状对降低代谢率的物质反应良好，如玫瑰花瓣果酱[1,2,3,7]。结论代谢变化影响气管支气管树炎症的可能机制可能与呼吸道有关，呼吸道是机体热、水释放和体温调节的部位之一。在冬季和春季，人体处于高代谢状态，导致身体和呼吸道的保温。当温度升高或任何病毒暴露时，它就会阻碍身体现有的新陈代谢，从而导致身体和呼吸道中的热量或水分释放，以呼吸道炎症的形式出现，哮喘症状加剧。当这样的病人服用热的物质，如丁香，具有增加身体新陈代谢的特性，将恢复到以前的新陈代谢。因此，身体和呼吸道会有保温，呼吸道炎症会减少，反过来，这将有助于减轻哮喘的症状。在夏季和秋季，人体处于低代谢状态，导致身体和呼吸道释放热量和水分。当环境温度降低或任何病毒暴露时，它就会阻碍身体现有的新陈代谢从而导致热量或水分在体内和呼吸道中被保存以呼吸道炎症的形式出现哮喘症状加剧。当这些病人服用具有降低身体新陈代谢特性的冷却物质，如玫瑰花瓣果酱，会恢复到以前的新陈代谢。因此，身体和呼吸道会释放热量或水分，从而减少呼吸道的炎症，从而有助于减轻哮喘的症状。呼吸道病毒通过呼吸道进入人体，但进入血液后产生发热并影响中枢水平(下丘脑)的体温调节机制。预防措施/临床意义夏季/秋季哮喘发作的注意事项:在日常饮食中加入各种冷却物质，如时令水果、时令蔬菜、甘露、酪乳、玫瑰花瓣果酱、小豆蔻。Saxena T(2019)哮喘治疗与季节性代谢变化的关系vol . 3: 2-2 Med Res Innov, 2019 doi: 10.15761/MRI。1000159 2。从4月到10月，哮喘患者应该定期在清晨散步，这有助于身体适应凉爽的空气，有助于防止冬季哮喘发作。3.哮喘患者应该在早晨在户外、屋顶和花园做瑜伽/运动，以发展对环境的适应和增加肺活量。4. 在夏季的病毒性哮喘症状中，对身体有凉爽作用/降低BMR的中枢作用物质，如香旋花或假马齿苋，是有用的。须知1。 哮喘患者应避免辛辣食物，如披萨等性质较热的快餐，增加新陈代谢，对身体的放热机制造成更多负担。2. 冷饮，冰水或冷饮后立即暴露自己的高温(试图给现有的新陈代谢相反的信号)，并突然试图改变BMR。冬季/春季预防哮喘发作的注意事项在日常饮食中加入一些可以提高BMR的香料，比如丁香、月桂叶、黑胡椒。2. 定期补充热饮，如茶、咖啡和汤。3.在你的日常饮食中摄取大量的时令水果和蔬菜。4. 哮喘患者应关闭窗户，避免暴露在冷空气中。5. 注意保暖，在室外活动时围上围巾，避免接触冷空气。6. 通过经常洗手来控制细菌。7. 在冬季病毒性哮喘症状后，中枢作用物质对身体有温暖作用/增加BMR，如咖啡/茶/罂粟花是有用的。8. 7-8
{"title":"Asthma treatment with its relation to changes in seasonal metabolism","authors":"Tarun Saxena, Azeema Ozefa Ali, M. Saxena","doi":"10.15761/mri.1000159","DOIUrl":"https://doi.org/10.15761/mri.1000159","url":null,"abstract":"Seasonal asthma/ post viral asthma produces epidemic like condition in developed and developing countries which causes a huge burden to the society socially as well as economically with an increase in morbidity and mortality. This review highlights the preventive steps in controlling seasonal asthma symptoms. *Correspondence to: Tarun Saxena, Department of Internal Medicine, Mittal Hospital and Research Centre, Ajmer, Rajasthan, India, Tel: +91-9829089284, E-mail: yogdiab@gmail.com/info@mittalhospital.com Received: June 07, 2019; Accepted: June 21, 2019; Published: June 24, 2019 Introduction The worldwide incidences of bronchial asthma are increasing. The correlation between metabolism (basal metabolic rate/BMR) and asthma treatment is less clear in the literature due to the presence of multiple risk factors in the causation of asthma. Seasonal variations are also reported in both BMR and asthma [1-7]. Methods Various studies have been used to review the process [1-16]. Results: Studies describe that metabolism changes with environmental temperature and season. It is also found that the asthma epidemic occurs during the change of season i.e. winter to summer, maximum attack rate during spring; and summer to winter, maximum attack rate during autumn/pre-winter. A clear association of asthma exacerbation and exposure to environmental air temperature is found. If environmental temperature opposes existing metabolism e.g. rise in temperature during spring tries to reduce BMR opposite to high BMR of winters and conversely in autumn low BMR of summer is opposed by mild cool air in pre winter. This alteration exacerbates asthma symptoms. In winter and spring, the metabolism remains high and asthma symptoms respond well to substances which increase the metabolic rate, such as clove. In summer and autumn, the metabolism remains low and asthma symptoms respond well to substances which reduce the metabolic rate, like rose petal jam [1,2,3,7]. Conclusion The possible mechanism by which change in metabolism affects inflammation in the tracheobronchial tree seems to involve the respiratory tract, as one of the sites of heat and water release and thermoregulation in the body. During Winter/spring there is a high metabolic state which causes heat preservation in the body along with the respiratory tract. When there is an increase in temperature or any viral exposure then it opposes the existing metabolism of the body which leads to heat or water release in the body as well as in the respiratory tract in the form of inflammation in the respiratory tract with exacerbation of asthmatic symptoms. When such patients are administered hot substances like clove which has properties to increase the body metabolism will revert to its previous metabolism. Thus there will be heat preservation in the body and respiratory tract and decrease in inflammation in the respiratory tract and this, in turn, will help to reduce the symptoms of asthma. During Summer/Autumn there is a l","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Paraskevas, V. Constantinides, E. Kararizou, S. Vassilopoulou, P. Paraskevas, E. Kapaki
Hereditary forms of subcortical small vessel disease (SSVD) leading to vascular cognitive impairment (VCI) comprise a heterogeneous group of rare genetic disorders, suitable for the study of the mechanisms and relationship between SSVD and VCI. Since these disorders are rare, better knowledge of their clinical, genetic, imaging and biochemical characteristics may be achievable only through registries which additional may help in better recruitment of patients for studies. A great amount of our current knowledge on these disorders has been gained through registries and data bases. International registries may further help in expanding our experience in epidemiological or even preventive and therapeutic aspects of hereditary SSVD.
{"title":"Hereditary forms of subcortical small vessel disease. The need for registries","authors":"G. Paraskevas, V. Constantinides, E. Kararizou, S. Vassilopoulou, P. Paraskevas, E. Kapaki","doi":"10.15761/mri.1000152","DOIUrl":"https://doi.org/10.15761/mri.1000152","url":null,"abstract":"Hereditary forms of subcortical small vessel disease (SSVD) leading to vascular cognitive impairment (VCI) comprise a heterogeneous group of rare genetic disorders, suitable for the study of the mechanisms and relationship between SSVD and VCI. Since these disorders are rare, better knowledge of their clinical, genetic, imaging and biochemical characteristics may be achievable only through registries which additional may help in better recruitment of patients for studies. A great amount of our current knowledge on these disorders has been gained through registries and data bases. International registries may further help in expanding our experience in epidemiological or even preventive and therapeutic aspects of hereditary SSVD.","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Demirel, Ibrahim Donmez, E. Uçaroğlu, A. Yüksel
Despite decreased incidence and mortality rates in recent years, coronary heart diseases remain one of the leading causes of death. According to TEKHARF study by the Turkish Cardiology Society, 2 million people have coronary artery disease in Turkey. According to TEKHARF data, cardiovascular diseases are responsible for 45% of all deaths in our country [3]. It is estimated that the number of patients with heart disease will reach 3.4 million if this negative situation, similar to the rates in developed countries, continues [2].
{"title":"Acute coronary syndromes and diagnostic methods","authors":"M. Demirel, Ibrahim Donmez, E. Uçaroğlu, A. Yüksel","doi":"10.15761/mri.1000167","DOIUrl":"https://doi.org/10.15761/mri.1000167","url":null,"abstract":"Despite decreased incidence and mortality rates in recent years, coronary heart diseases remain one of the leading causes of death. According to TEKHARF study by the Turkish Cardiology Society, 2 million people have coronary artery disease in Turkey. According to TEKHARF data, cardiovascular diseases are responsible for 45% of all deaths in our country [3]. It is estimated that the number of patients with heart disease will reach 3.4 million if this negative situation, similar to the rates in developed countries, continues [2].","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maíra L Schwaab, Victor O Derossi, E. N. Usuy, César Lazzarotto, A. Hofstaetter
The silicone ring of Roux-en-Y Gastric Bypass can determine benefits in long-term weight loss [1], but complications occur in about 1% of cases [2]. For example, ring slip, which consists of distal displacement, outside the gastric pouch towards the jejunum, causes secondary compression and symptoms such as post-eating vomiting, food intolerance and even malnutrition [3,4]. The technique for removing the ring by surgery is more frequently used [5], but in this case-report we will describe an endoscopic approach of removal [6,7]. The objective of this case report is to demonstrate the endoscopic technique of gastric ring removal through the use of self-expanding plastic prosthesis.
{"title":"Endoscopic withdrawal of bariatric ring with the use of plastic prosthesis – A case report","authors":"Maíra L Schwaab, Victor O Derossi, E. N. Usuy, César Lazzarotto, A. Hofstaetter","doi":"10.15761/mri.1000156","DOIUrl":"https://doi.org/10.15761/mri.1000156","url":null,"abstract":"The silicone ring of Roux-en-Y Gastric Bypass can determine benefits in long-term weight loss [1], but complications occur in about 1% of cases [2]. For example, ring slip, which consists of distal displacement, outside the gastric pouch towards the jejunum, causes secondary compression and symptoms such as post-eating vomiting, food intolerance and even malnutrition [3,4]. The technique for removing the ring by surgery is more frequently used [5], but in this case-report we will describe an endoscopic approach of removal [6,7]. The objective of this case report is to demonstrate the endoscopic technique of gastric ring removal through the use of self-expanding plastic prosthesis.","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of adherence to chronic obstructive pulmonary disease prescribing guidelines- A single centre study","authors":"V. Khalil, A. Hua, S. Lam","doi":"10.15761/mri.1000161","DOIUrl":"https://doi.org/10.15761/mri.1000161","url":null,"abstract":"","PeriodicalId":93126,"journal":{"name":"Medical research and innovations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67499752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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