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The Prevalence of Bovine Trypanosomiasis in JabiTehnan District of Amhara Regional State, Ethiopia 埃塞俄比亚阿姆哈拉州JabiTehnan区牛锥虫病流行情况
Pub Date : 2018-07-16 DOI: 10.19080/IJCSMB.2018.04.555649
Melak Wondie
Livestock is backbone of the socio-economic system of most of the rural communities of Africa [1]. Ethiopia is known for its large and diverse livestock resource endowments. Livestock is primarily kept on small holdings where it provides drought power for crop production, manure for soil fertility and fuels, serves as a sources of family diet and sources of cash income (from sale of livestock and livestock products). Despite large livestock population, Ethiopia fails to optimally utilize this resource due to different constrains facing the livestock subsector. Shortage of nutrition, reproductive insufficiency, management constraints and animal disease are the major constraints [2]. One of the diseases hampering the livestock subsector is trypanosomosis [3]. Trypanosomosis is a complex disease of protozoa that is caused by different species of unicellular parasites (trypanosome) found in the blood and other tissues of vertebrates, including livestock, wild life and people [4]. Trypanosomosis limited to the extension of natural herds particularly in Africa were the presence of the tsetse fly density access to woodland and savanna areas with good grazing potential [3]. It is a serious constraint to agricultural production in extensive areas of the tsetse infested regions which accounts over 10 million squares of the tropical Africa [5]. Ethiopia is one of the countries suffering from the impact of trypanosomosis. In Ethiopia, it is estimated that some 10 to 14 million heads of cattle and an equivalent number of small ruminants together with a significant number of equines and camels, are exposed to the risk of trypanosomosis [6]. Six species of trypanosomes are recorded in Ethiopia and the most important trypanosomes in terms of economic loss in domestic livestock are the tsetse transmitted species T. congolense, T. vivax and T. brucei [3].
畜牧业是非洲大多数农村社区社会经济体系的支柱[1]。埃塞俄比亚以其丰富多样的畜牧资源而闻名。牲畜主要饲养在小农场,为作物生产提供抗旱能力,为土壤肥力和燃料提供肥料,作为家庭饮食和现金收入来源(来自牲畜和畜产品的销售)。尽管畜牧业人口众多,但由于畜牧业部门面临的不同限制,埃塞俄比亚未能最佳利用这一资源。营养短缺、生殖不足、管理制约和动物疾病是主要制约因素[2]。阻碍畜牧业分部门发展的疾病之一是锥虫病[3]。锥虫病是一种复杂的原生动物疾病,由脊椎动物血液和其他组织中发现的不同种类的单细胞寄生虫(锥虫体)引起,包括牲畜、野生动物和人[4]。锥虫病仅限于自然种群的扩展,特别是在非洲,存在密度较高的采采蝇进入具有良好放牧潜力的林地和稀树草原[3]。它严重制约了热带非洲超过1000万平方公里的舌蝇疫区的农业生产[5]。埃塞俄比亚是遭受锥虫病影响的国家之一。据估计,在埃塞俄比亚,约有1000万至1400万头牛和相当数量的小型反刍动物,以及大量的马和骆驼,面临锥虫病的风险[6]。埃塞俄比亚记录了六种锥虫,就家畜的经济损失而言,最重要的锥虫是舌蝇传播物种刚果锥虫、间日锥虫和布鲁氏锥虫[3]。
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引用次数: 1
Relationship between serum ghrelin levels, weight loss and quality of life in patients with advanced non-small cell lung cancer 晚期非小细胞肺癌患者血清胃饥饿素水平、体重减轻和生活质量的关系
Pub Date : 2018-07-10 DOI: 10.19080/IJCSMB.2018.04.555648
Gokcen Demiray
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引用次数: 1
Ribosomopathies: Many Questions and A Few Answers 核糖体病:许多问题和一些答案
Pub Date : 2018-07-05 DOI: 10.19080/ijcsmb.2018.04.555647
N. Andini
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引用次数: 4
Ribosomopathies: Many Questions and A Few Answers 核糖体病:许多问题和几个答案
Pub Date : 2018-06-06 DOI: 10.19080/ijcsmb.2018.04.555646
Nahla Am
Ribosomes are essential components of the protein synthesis machinery [1]. Ribosomes are large complex molecules [2] comprised of ribosomal RNA (rRNA), ribosomal proteins (RPs), and small nucleolar RNAs (snoRNAs) [3]. rRNA catalyzes peptide bond formation during protein synthesis; RPs optimize rRNA processing and stabilize the ribosome’s final structure; and snoRNAs primarily regulate chemical modifications of other RNAs [3]. RNA and protein are assembled into a functional, multi-subunit enzyme [2]. Ribosomes are universally responsible for the quality and quantity of proteins in all cells [4]. RPs has extra-ribosomal functions that are involved in cell proliferation, differentiation, apoptosis, DNA repair, and other cellular processes. A subset of RPs also acts as “watch guards” to detect the defects in ribosome biogenesis (the synthesis of the ribosome) [1].
核糖体是蛋白质合成机制的重要组成部分。核糖体是由核糖体RNA (rRNA)、核糖体蛋白(RPs)和小核仁RNA (snoRNAs)[3]组成的大分子复合物。在蛋白质合成过程中,rRNA催化肽键的形成;RPs优化rRNA加工,稳定核糖体的最终结构;snorna主要调控其他rna的化学修饰[3]。RNA和蛋白质组装成一个功能齐全的多亚基酶[2]。核糖体普遍负责所有细胞中蛋白质的质量和数量。RPs具有核糖体外功能,参与细胞增殖、分化、凋亡、DNA修复和其他细胞过程。RPs的一个子集还充当“看守”来检测核糖体生物发生(核糖体的合成)[1]中的缺陷。
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引用次数: 0
Impact of Heat Shock Proteins in Hepatocellular Carcinoma 热休克蛋白在肝细胞癌中的作用
Pub Date : 2018-06-02 DOI: 10.19080/ijcsmb.2018.05.555663
M. Parmar
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引用次数: 0
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International journal of cell science & molecular biology
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