Pub Date : 2023-08-23DOI: 10.46439/ophthalmology.5.031
M. Delsoz, S. H. Mousavi, P. Hollands
{"title":"Bevacizumab (Avastin) in treatment of maculopathy secondary to proliferative diabetic retinopathy (PDR) in Afghanistan","authors":"M. Delsoz, S. H. Mousavi, P. Hollands","doi":"10.46439/ophthalmology.5.031","DOIUrl":"https://doi.org/10.46439/ophthalmology.5.031","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"2008 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41331292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Orbital lymphoproliferative disorders (OLPDs) consist of a spectrum of diseases ranging from benign to malignant lesions including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. OLPDs rarely present as an orbital mass lesion in children. Accurate discrimination of OLPDs is crucial for treatment planning. We report a case to investigate the clinical and pathological features of OLPDs in children. Case presentation: A 3-year-old female with orbital mass was admitted to the hospital and proceeded to have a CT orbit which showed an orbital mass. The orbital mass was removed after operation and pathologic diagnosis was identified. Pathological diagnosis with histopathological features and immunohistochemical markers was lymphoproliferative lesion in the left orbit. The diagnosis was consistent with OLPDs. There was no recurrence after one-year follow-up. Conclusions: OLPDs are rare in children. The clinical manifestations and imaging have no specificity; pathological diagnosis with histopathological features and immunohistochemical markers is the main basis for the diagnosis and treatment.
{"title":"Orbital Lymphoproliferative Disorders (OLPDs) in a 3-year-old Child: Case Report and Review of Literature","authors":"Cai-ping Shi, Jia Feng, Sujuan Zhao, Jiao Zhan, Yanhong Ren, W. Gu, Xiaoyu Zheng","doi":"10.33696/ophthalmology.3.011","DOIUrl":"https://doi.org/10.33696/ophthalmology.3.011","url":null,"abstract":"Background: Orbital lymphoproliferative disorders (OLPDs) consist of a spectrum of diseases ranging from benign to malignant lesions including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. OLPDs rarely present as an orbital mass lesion in children. Accurate discrimination of OLPDs is crucial for treatment planning. We report a case to investigate the clinical and pathological features of OLPDs in children.\u0000\u0000Case presentation: A 3-year-old female with orbital mass was admitted to the hospital and proceeded to have a CT orbit which showed an orbital mass. The orbital mass was removed after operation and pathologic diagnosis was identified. Pathological diagnosis with histopathological features and immunohistochemical markers was lymphoproliferative lesion in the left orbit. The diagnosis was consistent with OLPDs. There was no recurrence after one-year follow-up.\u0000\u0000Conclusions: OLPDs are rare in children. The clinical manifestations and imaging have no specificity; pathological diagnosis with histopathological features and immunohistochemical markers is the main basis for the diagnosis and treatment.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74543139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-16DOI: 10.33696/ophthalmology.3.012
Yogesh Kumar, J. Bhalla, Ridhima Sakhuja, Neha Yadav
A patient with a unilateral congenital vitreous cyst attached to the posterior lens capsule is now described, with its photographic appearance.
一例单侧先天性玻璃体囊肿附于晶状体后囊的病例，并附其摄影表现。
{"title":"A Rare Case of Vitreous Cyst","authors":"Yogesh Kumar, J. Bhalla, Ridhima Sakhuja, Neha Yadav","doi":"10.33696/ophthalmology.3.012","DOIUrl":"https://doi.org/10.33696/ophthalmology.3.012","url":null,"abstract":"A patient with a unilateral congenital vitreous cyst attached to the posterior lens capsule is now described, with its photographic appearance.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"127 14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87756138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-11DOI: 10.33696/ophthalmology.3.010
Maxime Depasse, M. T. ten Tusscher, Vincent M. De La Porte, R. Kuijpers
Purpose: To describe 3 cases of acute macular neuroretinopathy (AMN) type 2 associated with SARS-CoV-2 viral infection and migraine. Methods: Observational case series and literature review. Results: The three patients, which were all women in their reproductive years with a mean age of 31 (range, 22-43), were diagnosed with AMN type 2 after presenting with acute onset of uni- or bilateral persisting paracentral scotomata. On multi-modal imaging with near-infrared (NIR) reflectance imaging, wedge-shaped dark-gray lesions were discernable in a perifoveal petaloid configuration. SD-OCT through the lesions revealed initial hyperreflectivity at the level of the outer retina, beneath the OPL (outer plexiform layer) and comprising the ONL (outer nuclear layer), with disruption of the inner segment/outer segment (IS/OS) band, eventually evolving into thinning of the ONL with or without persisting disruption of the photoreceptor complex. Anterior segment, fundoscopic, angiographic and electrophysiologic examinations were unremarkable. Conclusion: All three cases were diagnosed with a concurrent viral upper respiratory tract infection caused by the SARS-CoV-2 virus. While AMN is considered to be a rare disease, a worldwide surge in the incidence of AMN has recently been reported and the largest case series to date have been described during the latest SARS-CoV-2 viral pandemic. Thus, COVID-19 could be considered a potential risk factor for the development of AMN type 2. Two of our cases were associated with migraine, one of which experienced the onset of AMN symptoms in the immediate setting of a migraine attack and the use of triptans. This association between migraine, triptans and AMN type 2 should be considered in the context of a seemingly persisting visual aura, particularly in the presence of additional risk factors, such as female gender and oral contraceptive use. Summary statement An increased incidence of acute macular neuroretinopathy (AMN) type 2 is observed in the context of SARS-CoV-2 viral infection. The presently described association between AMN, migraine, and triptans should be considered when examining a patient with seemingly persisting visual aura, in particular negative scotomata, in the context of migraine.
{"title":"Are Women with COVID-19 and Migraine Prone to AMN Type 2?","authors":"Maxime Depasse, M. T. ten Tusscher, Vincent M. De La Porte, R. Kuijpers","doi":"10.33696/ophthalmology.3.010","DOIUrl":"https://doi.org/10.33696/ophthalmology.3.010","url":null,"abstract":"Purpose: To describe 3 cases of acute macular neuroretinopathy (AMN) type 2 associated with SARS-CoV-2 viral infection and migraine.\u0000Methods: Observational case series and literature review.\u0000Results: The three patients, which were all women in their reproductive years with a mean age of 31 (range, 22-43), were diagnosed with AMN type 2 after presenting with acute onset of uni- or bilateral persisting paracentral scotomata. On multi-modal imaging with near-infrared (NIR) reflectance imaging, wedge-shaped dark-gray lesions were discernable in a perifoveal petaloid configuration. SD-OCT through the lesions revealed initial hyperreflectivity at the level of the outer retina, beneath the OPL (outer plexiform layer) and comprising the ONL (outer nuclear layer), with disruption of the inner segment/outer segment (IS/OS) band, eventually evolving into thinning of the ONL with or without persisting disruption of the photoreceptor complex. Anterior segment, fundoscopic, angiographic and electrophysiologic examinations were unremarkable.\u0000Conclusion: All three cases were diagnosed with a concurrent viral upper respiratory tract infection caused by the SARS-CoV-2 virus. While AMN is considered to be a rare disease, a worldwide surge in the incidence of AMN has recently been reported and the largest case series to date have been described during the latest SARS-CoV-2 viral pandemic. Thus, COVID-19 could be considered a potential risk factor for the development of AMN type 2. Two of our cases were associated with migraine, one of which experienced the onset of AMN symptoms in the immediate setting of a migraine attack and the use of triptans. This association between migraine, triptans and AMN type 2 should be considered in the context of a seemingly persisting visual aura, particularly in the presence of additional risk factors, such as female gender and oral contraceptive use.\u0000Summary statement \u0000An increased incidence of acute macular neuroretinopathy (AMN) type 2 is observed in the context of SARS-CoV-2 viral infection. The presently described association between AMN, migraine, and triptans should be considered when examining a patient with seemingly persisting visual aura, in particular negative scotomata, in the context of migraine.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85209388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-25DOI: 10.33696/ophthalmology.3.009
A. Mackay
Last year’s article In the International Journal of Clinical and Experimental Ophthalmology [1] highlighted that Cortical Visual Impairment (CVI) is now the leading cause of visual impairment in the developed world [2]. It also provided a definition of CVI [3,4], and summarized its functional deficits, and methods of assessment. Different sources report vastly different incidence of Visual Acuity (VA) reduction in CVI, ranging from 83% [5] to just a small minority [6]. However, the implication is the samescreening of many aspects of vision may be required in infancy, not just VA.
{"title":"Assessment of Visual Function for Education: A Commentary on ‘VEP Visual Acuity in Children with Cortical Visual Impairment’","authors":"A. Mackay","doi":"10.33696/ophthalmology.3.009","DOIUrl":"https://doi.org/10.33696/ophthalmology.3.009","url":null,"abstract":"Last year’s article In the International Journal of Clinical and Experimental Ophthalmology [1] highlighted that Cortical Visual Impairment (CVI) is now the leading cause of visual impairment in the developed world [2]. It also provided a definition of CVI [3,4], and summarized its functional deficits, and methods of assessment. Different sources report vastly different incidence of Visual Acuity (VA) reduction in CVI, ranging from 83% [5] to just a small minority [6]. However, the implication is the samescreening of many aspects of vision may be required in infancy, not just VA.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82447553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-25DOI: 10.33696/ophthalmology.3.008
P. Gouws, Alexander Gouws
This is the first reported case of COVID-19 associated optic neuritis (ON) presenting with classic Uhtoff’s phenomenon typically associated with multiple sclerosis (MS). Uhthoff phenomenon, also known as Uhthoff sign or syndrome, is a transient worsening of neurological function lasting less than 24 hours that can occur in multiple sclerosis patients due to increases in core body temperature. There have been some case reports of ON associated with COVID-19 infection but no reports of ON mimicking MS. The patient’s symptoms resolved very slowly and was not affected by receiving a vaccination against COVID-19.
{"title":"Uhthoff ’s Phenomenon as Presentation of COVID-19 Infection","authors":"P. Gouws, Alexander Gouws","doi":"10.33696/ophthalmology.3.008","DOIUrl":"https://doi.org/10.33696/ophthalmology.3.008","url":null,"abstract":"This is the first reported case of COVID-19 associated optic neuritis (ON) presenting with classic Uhtoff’s phenomenon typically associated with multiple sclerosis (MS). Uhthoff phenomenon, also known as Uhthoff sign or syndrome, is a transient worsening of neurological function lasting less than 24 hours that can occur in multiple sclerosis patients due to increases in core body temperature.\u0000\u0000There have been some case reports of ON associated with COVID-19 infection but no reports of ON mimicking MS.\u0000\u0000The patient’s symptoms resolved very slowly and was not affected by receiving a vaccination against COVID-19.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82857037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.46439/ophthalmology.4.030
Jeanie C Lucy
Background: The COVID-19 pandemic in the United States is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms can vary in COVID-19 among which central nervous system (CNS) involvement can be included. As this disease is studied locally, nationally and globally, attention to neurological manifestations presentations should be documented for better understanding. Methods: A clinical case of trigeminal neuralgia will be discussed along with presentation of signs, symptoms, differential diagnosis and the potential association of it with COVID-19. Results: A 41-year-old woman presented to the clinic for a routine eye examination which was prompted by chronic facial pain on one side described as constantly dull up to excruciatingly painful when brushing her teeth. No other neurological pain was reported. The patient was diagnosed with Sar-CoV-2 and subsequently trigeminal neuralgia two weeks after testing negative COVID-19. Conclusion: Trigeminal neuralgia may be triggered after testing positive for COVID-19, yet further investigations are needed.
{"title":"A case of trigeminal neuralgia after COVID-19","authors":"Jeanie C Lucy","doi":"10.46439/ophthalmology.4.030","DOIUrl":"https://doi.org/10.46439/ophthalmology.4.030","url":null,"abstract":"Background: The COVID-19 pandemic in the United States is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms can vary in COVID-19 among which central nervous system (CNS) involvement can be included. As this disease is studied locally, nationally and globally, attention to neurological manifestations presentations should be documented for better understanding.\u0000\u0000Methods: A clinical case of trigeminal neuralgia will be discussed along with presentation of signs, symptoms, differential diagnosis and the potential association of it with COVID-19.\u0000\u0000Results: A 41-year-old woman presented to the clinic for a routine eye examination which was prompted by chronic facial pain on one side described as constantly dull up to excruciatingly painful when brushing her teeth. No other neurological pain was reported. The patient was diagnosed with Sar-CoV-2 and subsequently trigeminal neuralgia two weeks after testing negative COVID-19.\u0000\u0000Conclusion: Trigeminal neuralgia may be triggered after testing positive for COVID-19, yet further investigations are needed.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46516535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.46439/ophthalmology.4.029
{"title":"“Poppers Maculopathy” is an Electrochemical Overload","authors":"","doi":"10.46439/ophthalmology.4.029","DOIUrl":"https://doi.org/10.46439/ophthalmology.4.029","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48365807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-12DOI: 10.33696/ophthalmology.2.006
Sweety Trivedi, A. Chakravarty
The case of a young girl with Dengue fever presenting with seizures and bilateral visual loss is presented. At the time of presentation, she had right hemiplegia and dysarthria but was not dysphasic. Fundoscopy revealed presence of macular and disc oedema in the right eye and vitreous haemorrhage in the left eye. Dengue IgM antibody was positive. Magnetic resonance imaging revealed a large intracerebral spontaneous haemorrhage. She had partial recovery of her hemiplegia and speech as well as of her vision on conservative treatment. The relevant literature relating to ocular involvement and strokes in association with Dengue fever has been reviewed.
{"title":"Stroke and Visual Loss in a Young Girl with Dengue Fever – Report of a Case and a Mini Review","authors":"Sweety Trivedi, A. Chakravarty","doi":"10.33696/ophthalmology.2.006","DOIUrl":"https://doi.org/10.33696/ophthalmology.2.006","url":null,"abstract":"The case of a young girl with Dengue fever presenting with seizures and bilateral visual loss is presented. At the time of presentation, she had right hemiplegia and dysarthria but was not dysphasic. Fundoscopy revealed presence of macular and disc oedema in the right eye and vitreous haemorrhage in the left eye. Dengue IgM antibody was positive. Magnetic resonance imaging revealed a large intracerebral spontaneous haemorrhage. She had partial recovery of her hemiplegia and speech as well as of her vision on conservative treatment. The relevant literature relating to ocular involvement and strokes in association with Dengue fever has been reviewed.","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75577985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-01DOI: 10.33696/ophthalmology.2.005
Qing Lv, Ailian Du
{"title":"Comment on “Retinitis Pigmentosa and Molar Tooth Sign Caused by Novel AHI1 Compound Heterozygote Pathogenic Variants: A Case Report”","authors":"Qing Lv, Ailian Du","doi":"10.33696/ophthalmology.2.005","DOIUrl":"https://doi.org/10.33696/ophthalmology.2.005","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73703450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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