Pub Date : 2020-09-23DOI: 10.46439/ophthalmology.2.013
{"title":"Pterygium excision with conjunctival autograft using Tisseel glue; 6-year outcomes from a UK tertiary referral corneal unit","authors":"","doi":"10.46439/ophthalmology.2.013","DOIUrl":"https://doi.org/10.46439/ophthalmology.2.013","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43332271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-14DOI: 10.46439/ophthalmology.2.006
{"title":"New frontiers in the rehabilitation of neurological damage","authors":"","doi":"10.46439/ophthalmology.2.006","DOIUrl":"https://doi.org/10.46439/ophthalmology.2.006","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44373050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-14DOI: 10.46439/ophthalmology.2.009
{"title":"The GSK3β pathway in optic nerve regeneration","authors":"","doi":"10.46439/ophthalmology.2.009","DOIUrl":"https://doi.org/10.46439/ophthalmology.2.009","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47469964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-14DOI: 10.46439/ophthalmology.2.010
{"title":"Acanthamoeba keratitis - is there another perspective - Extrapolations from the Acanthamoeba – fungal keratitis study","authors":"","doi":"10.46439/ophthalmology.2.010","DOIUrl":"https://doi.org/10.46439/ophthalmology.2.010","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44563907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-14DOI: 10.46439/ophthalmology.2.008
{"title":"Ocular surface squamous neoplasia treated with topical chemotherapy","authors":"","doi":"10.46439/ophthalmology.2.008","DOIUrl":"https://doi.org/10.46439/ophthalmology.2.008","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49401777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01Epub Date: 2020-09-08DOI: 10.46439/ophthalmology.2.017
Xin Yee Ooi, Rujman Khan, Anjalee Choudhury, Francisco Xavier Elisarraras, Jeff Grigsby, Brandi Obregon, Andrew Tsin
Since the publication of our previous paper, Visual cycle proteins: Structure, function, and roles in human retinal disease (Tsin, et.al, JBC 293:13016, 2018) there has been significant progress on multiple topics discussed in this paper. In the present communication, we further explore research advances on two visual cycle proteins: DES1 and IRBP. In addition, we emphasize the progress of clinical translation of other visual cycle protein research, including the breakthrough of FDA-approved gene therapy for Leber's congenital amaurosis, and additional gene therapies at different stages of clinical trials for various retinal diseases such as retinitis pigmentosa, diabetic retinopathy, and Stargardt's disease.
{"title":"Recent advances on visual cycle protein research and progress on clinical translation.","authors":"Xin Yee Ooi, Rujman Khan, Anjalee Choudhury, Francisco Xavier Elisarraras, Jeff Grigsby, Brandi Obregon, Andrew Tsin","doi":"10.46439/ophthalmology.2.017","DOIUrl":"https://doi.org/10.46439/ophthalmology.2.017","url":null,"abstract":"<p><p>Since the publication of our previous paper, <i>Visual cycle proteins: Structure, function, and roles in human retinal disease</i> (Tsin, et.al, JBC 293:13016, 2018) there has been significant progress on multiple topics discussed in this paper. In the present communication, we further explore research advances on two visual cycle proteins: DES1 and IRBP. In addition, we emphasize the progress of clinical translation of other visual cycle protein research, including the breakthrough of FDA-approved gene therapy for Leber's congenital amaurosis, and additional gene therapies at different stages of clinical trials for various retinal diseases such as retinitis pigmentosa, diabetic retinopathy, and Stargardt's disease.</p>","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"2 3","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39379487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.46439/ophthalmology.1.003
{"title":"How many mutations does it take to make a uveal melanoma","authors":"","doi":"10.46439/ophthalmology.1.003","DOIUrl":"https://doi.org/10.46439/ophthalmology.1.003","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47793900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.46439/ophthalmology.1.002
{"title":"Presbyopia correcting IOLs and the ocular surface disease… The good, the bad and the ugly","authors":"","doi":"10.46439/ophthalmology.1.002","DOIUrl":"https://doi.org/10.46439/ophthalmology.1.002","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45477646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.46439/ophthalmology.1.004
{"title":"MSICS is a simple solution for a big problem","authors":"","doi":"10.46439/ophthalmology.1.004","DOIUrl":"https://doi.org/10.46439/ophthalmology.1.004","url":null,"abstract":"","PeriodicalId":93265,"journal":{"name":"Archives of clinical and experimental ophthalmology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42440879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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