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Different Birth Size Measures are Not Equivalent in Predicting Health Outcomes in Young Women 不同的出生尺寸在预测年轻女性健康结果方面并不等同
Pub Date : 2019-11-13 DOI: 10.24966/ncp-878x/100035
K. Pajer
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引用次数: 0
Long-Term Auditory Follow-Up of Preterm Infants after Neonatal Hearing Screening 新生儿听力筛查后早产儿的长期听觉随访
Pub Date : 2019-11-13 DOI: 10.24966/ncp-878x/100034
K. D. Graaff-Korf
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引用次数: 2
Examining the Association of Preeclampsia with Neonatal Neurodevelopmental Delay 子痫前期与新生儿神经发育迟缓的关系研究
Pub Date : 2019-11-13 DOI: 10.24966/ncp-878x/100036
Lea H Mallett
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引用次数: 0
Intrapartum Asphyxia in Relation with the Risk for Developing of Cerebral Palsy 产时窒息与脑瘫发生风险的关系
Pub Date : 2019-06-06 DOI: 10.24966/ncp-878x/100030
M. Vințan
Background and goals Neonatal hypoxic-ischemic injury defined as: “Asphyxia of the umbilical blood supply to the human fetus occurring at 36 gestational weeks or later”, represents still a stable cause of mortality and disability despite the progress in assisted respiratory and intensive care technology. It is thought to be the major cause for developing of Cerebral Palsy (CP). We performed an observational study that included children with cerebral palsy, in order to asses the relation of intrapartum asphyxia and CP. Methods Our group included children with diagnosis of CP, age under 5 years with same characteristics regardind sex, families social and educational level. There were excluded children with malformations, braintumors, neurometabolic and neurodegenerative disorders. We evaluated the relation between the presence of intrapartum asphyxia and type of CP, type of neurological involvement: Spastic, extrapiramidal or mixt and the relation with CP comorbidities as motor and mental retardation and epilepsy. Results We evaluated 110 children with CP 63 females (57 %) and 47 males (43 %); 43 of them (39 %) presented documented intrapartum asphyxia. The type of CP was dominating spastic type (79 %), associated with motor retardation in 102 (92 %), cognitive disability in 81 (73,63 %) and epilepsy in 53 of them (48 %). We found possible relationship for developing distonic and mixt type of neurological involvement, no relation regarding the type of CP tetraparesis, diparesis or hemiparesis. In our group, no relationship was found regarding motor and mental retardation and history of intrapartum asphyxia, instead there was a correlation with epilepsy in this group of children. Conclusion CP is a multifactorial disorder. Intrapartum asphyxia could be a factor that determines the type of CP and associated disabilities, but it is not specific. Probably studies on larger groups could better clarify the relation between CP and intrapartum asphyxia.
背景和目的新生儿缺氧缺血性损伤的定义是:“在妊娠36周或更晚发生的人类胎儿脐带血液供应窒息”,尽管辅助呼吸和重症监护技术取得了进展,但仍是导致死亡和残疾的稳定原因。它被认为是脑瘫(CP)发展的主要原因。我们对脑瘫患儿进行了一项观察性研究,以评估分娩时窒息与脑瘫的关系。方法我们的研究对象为诊断为脑瘫的儿童,年龄在5岁以下,性别、家庭、社会和文化水平相同。排除有畸形、脑肿瘤、神经代谢性和神经退行性疾病的儿童。我们评估了产时窒息的存在与脑瘫类型、神经受累类型(痉挛性、锥体外系或混合性)之间的关系,以及与脑瘫合并症(如运动、智力迟钝和癫痫)的关系。结果110例CP患儿中,女性63例(57%),男性47例(43%);其中43例(39%)表现为分娩时窒息。CP类型以痉挛型为主(79%),102例(92%)伴有运动迟缓,81例(73.63%)伴有认知障碍,53例(48%)伴有癫痫。我们发现可能与发展区域性和混合型神经受累有关,但与CP四瘫、肺瘫或偏瘫的类型无关。本组患儿的运动和智力发育迟滞与产时窒息史无相关性,而与癫痫有相关性。结论CP是一种多因素疾病。产时窒息可能是决定CP类型和相关残疾的一个因素,但它不是特异性的。可能对更大的群体进行研究可以更好地阐明CP与产时窒息之间的关系。
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引用次数: 0
Slow versus Rapid Advancement of Enteral Feeding in Preterm Infants Less than 34 Weeks: A Randomized Controlled Trial 34周以下早产儿肠内喂养的缓慢与快速进展:一项随机对照试验
Pub Date : 2019-06-06 DOI: 10.24966/ncp-878x/100029
L. Saha
per day have been reported as safe in a prospective study [7], but several retrospective studies have suggested that advancing feedings rapidly is associated with an increased risk for NEC [9,10]. In 1 of these studies, feeding increments were as high as 40 to 50mL/kg per day [9]. Conversely, a relatively more rapid advancement of enteral feedings in preterm infants may improve their growth and nutritional status, decrease the need for and hazards of intravenous infusion solutions, and potential ly shorten the length of hospitalization. Rayyis et al. [8], reported no difference in the incidence of feeding intolerance or NEC in infants who received 35 mL versus 15 mL feeding advancements. We exam ined whether infants who were fed initially and advanced at 30 mL/ kg per day take fewer days to get to full feedings than those who were fed initially and advanced at 20 mL/kg per day, without increases in their incidence of feeding complications and NEC. Also, we studied whether infants who were fed the higher volume regain birth weight earlier, have fewer days of intravenous fluids, and have a shorter hos pital stay than those who were advanced at the slower rate. Abstract Background Enteral feeding routines are not well defined in preterm neonates. Controversy exists regarding when feedings should be started, whether minimal enteral feedings should be used routinely in small preterm infants and how fast to advance enteral feedings. Objective To evaluate the effect of slow vs rapid rates of advancement of enteral feeding volumes on the clinical outcomes in preterm babies less than 34 weeks. A randomized, controlled, single-center trial was conducted in a Neonatal Unit of Dhaka Shishu (Children) Hospital. Infants between 1200 gm and < 2500 gm at birth, gestational age < 34 weeks, and weight appropriate for gestational age were allocated randomly to feedings of expressed human milk and advanced at either 30 mL/ kg per day or 20 mL/kg per day. Infant’s remained in the study until discharge. A total of 300 infants were enrolled, 150 infants in the rapid group and 150 in the slow group. Enteral feeding advancements were well tolerated by the intervention group of stable preterm neonates like that of control group both in birth weight <1500 gm and in birth weight (1500 gm - < 2500 gm) study populations (67.27 % vs. 68.42 % and 68.42 % vs. 64.28 %, p value > 0.05). Infants in the intervention group achieved full volume feedings sooner (9.33 days vs. 14.66 days) and (9.12 days vs. 15.5 days), p value < 0.05. Eighteen infants in the intervention group and fifteen in control group were died due to sepsis which was statistically not significant. There was no incidence of NEC in birth weight (1500 gm - < 2500 gm) study populations in both groups. No statistical differences in the proportion of infants with feed interruption or feed intolerance. Rapid enteral feeding advancements in preterm babies < 34 weeks reduce the time to reach full enteral feeding and the use of
在一项前瞻性研究中[7]已被报道为安全的,但几项回顾性研究表明,快速提前喂养与NEC风险增加有关[9,10]。在其中1项研究中,饲喂量高达40 ~ 50mL/kg /天[9]。相反,相对更快地推进早产儿肠内喂养可能会改善他们的生长和营养状况,减少静脉输液的需求和危害,并有可能缩短住院时间。Rayyis等人[8]报道,35 mL提前喂养与15 mL提前喂养的婴儿的喂养不耐受或NEC发生率无差异。我们检查了以每天30 mL/kg的剂量初始和晚期喂养的婴儿是否比那些以每天20 mL/kg的剂量初始和晚期喂养的婴儿需要更少的时间来获得完全喂养,而不会增加喂养并发症和NEC的发生率。此外,我们还研究了喂养量较大的婴儿是否比喂养量较慢的婴儿更早恢复出生体重,静脉输液天数更少,住院时间更短。背景:早产儿的肠内喂养程序没有很好的定义。关于何时开始喂养,是否应该在小早产儿中常规使用最低限度的肠内喂养以及肠内喂养的推进速度有多快存在争议。目的探讨肠内喂养量缓慢推进与快速推进对小于34周早产儿临床结局的影响。在达卡Shishu(儿童)医院的新生儿病房进行了一项随机、对照、单中心试验。出生时体重在1200克至2500克以下、胎龄< 34周、体重与胎龄相符的婴儿随机分配母乳喂养,并按30毫升/公斤/天或20毫升/公斤/天喂养。婴儿在出院前一直在研究中。共有300名婴儿被招募,150名婴儿在快速组,150名婴儿在慢速组。干预组稳健性早产儿肠内喂养提前的耐受性与对照组相当(出生体重0.05)。干预组实现全量喂养的时间较早(9.33天比14.66天)和(9.12天比15.5天),p值< 0.05。干预组18例患儿因败血症死亡,对照组15例患儿因败血症死亡,差异无统计学意义。两组出生体重(1500克- < 2500克)的研究人群中没有NEC的发病率。婴儿喂养中断或喂养不耐受的比例无统计学差异。< 34周的早产儿肠内喂养的快速进展减少了达到完全肠内喂养和使用PN给药的时间。快速推进肠内喂养也改善了这些高危婴儿的短期预后。
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引用次数: 4
Knowledge and Perception of Child Abuse among the Adolescent Girls in Some Selected Schools in Dhaka City 达卡市部分学校少女对虐待儿童的认知和感知
Pub Date : 2019-06-06 DOI: 10.24966/ncp-878x/100028
Shahria Hafiz
Background About 40 million children under the age of 18 years are estimated to suffer from abuse and neglect around the world. Child abuse in developing countries, including South Asia, is yet to be recognized as a major social and public health problem with an enormous burden on the economy and society. The present study conducted to find out the level of knowledge and perception of child abuse among the adolescent girls in some selected high schools in Dhaka city. Method This cross sectional descriptive study was conducted among 149 adolescent girl students of class VIII, IX and X of three purposively selected high schools in Dhaka city namely Kakoli High School, Rayer Bazar High School, and YWCA Higher Secondary Girls’ School. Results Mean±SD of age of the respondents was 14.23±0.90 years with a range of 13 to 16 years. Majority of them (61.7%) were in the age group of 13-14 years. When the respondents were asked from where they got information about child abuse, majority (123), 82% stated that they heard from TV, other common sources were news paper 65 (43%) and parents 36 (24%). In the present study out of 149 respondents said that physical abuse (66.4%) is more prevalent in our country than mental (55.7%) and sexual (29.5%) abuse. In the present study the respondents thought that child was abused by nearest relative, by servant, by teacher, by father, by mother, by brother and sister and by others 47.1%, 27.2%, 20.6%, 18.6%, 17.9%, 9.3% and 24.8% respectively. In the present study opinion of the respondents were sought as to how to prevent child abuse, increase peoples’ awareness, enforcement of law, and increase general level of education of the people and parents awareness about child mentality were the prominent opinions. The responses were scored and graded. Mean±SD of scores of knowledge was 11.7±2.5 with a range of 5-17. Only about 13% had high score while 30% scored poor. Mean±SD of scores of perception was 27.9±4.4 with a range of 14-35. Perception score of ‘poor’ grade was observed in 22% respondents and that of ‘good’ grade in 32% respondents. Relationship between knowledge score and perception score was examined by correlation analysis and a weak positive correlation was observed with correlation coefficient, r=0.186 (p=0.023). The mean±SD of scores of perception among Kakoli High School was 28.78±3.65, among the respondent among Rayer Bazar School was 26.93±5.056) and among the respondents of YWCA was 28.81±2.6. The mean±SD of score of knowledge among Kakoli School was 11.93±2.4, among the respondents of in Rayar Bazar School 11.01±2.34 and among the respondents of YWCA School was 13.52±2.01. From this study it was revealed that the knowledge and perception about child abuse is considerably significant. But in reality to counter the child abuse is not much practiced in our society. Therefore, the importance of child abuse should be focused and generalized with high priority.
据估计,全世界约有4000万18岁以下儿童遭受虐待和忽视。在包括南亚在内的发展中国家,虐待儿童问题尚未被认为是一个重大的社会和公共卫生问题,给经济和社会带来巨大负担。本研究旨在了解达卡市部分高中女生对虐待儿童的认知程度和认知程度。方法采用横断面描述性研究方法,对达卡市Kakoli高中、Rayer Bazar高中和YWCA高级中学女校八、九、十年级的149名青春期女生进行调查。结果调查对象年龄的平均值±SD为14.23±0.90岁,年龄范围为13 ~ 16岁。其中以13-14岁年龄组居多(61.7%)。当受访者被问及他们从哪里获得有关虐待儿童的信息时,大多数人(123人),82%的人表示他们从电视上听到,其他常见的来源是报纸65(43%)和父母36(24%)。在目前的研究中,149名受访者表示,在我国,身体虐待(66.4%)比精神虐待(55.7%)和性虐待(29.5%)更为普遍。在本次调查中,受访者认为孩子受到近亲属、仆人、老师、父亲、母亲、兄弟姐妹和其他人虐待的比例分别为47.1%、27.2%、20.6%、18.6%、17.9%、9.3%和24.8%。在本研究中,调查对象就如何预防虐待儿童、提高人们的意识、加强执法、提高民众的普遍教育水平和家长对儿童心理的认识等问题征求了意见。对这些回答进行评分和分级。知识得分的平均值±标准差为11.7±2.5,范围为5 ~ 17。只有13%的人得分高,30%的人得分低。知觉评分的均数±标准差为27.9±4.4,范围为14 ~ 35。22%的受访者的感知得分为“差”级,32%的受访者的感知得分为“好”级。对知识得分与感知得分进行相关分析,两者呈弱正相关,相关系数r=0.186 (p=0.023)。Kakoli高中、Rayer Bazar学校和YWCA的感知得分分别为28.78±3.65、26.93±5.056和28.81±2.6。Kakoli学校受访学生的知识得分平均值为11.93±2.4,Rayar Bazar学校受访学生的知识得分平均值为11.01±2.34,YWCA学校受访学生的知识得分平均值为13.52±2.01。从本研究中可以看出,对虐待儿童的认识和认知是相当显著的。但实际上,在我们的社会中,反对虐待儿童的做法并不多。因此,虐待儿童的重要性应得到高度重视和推广。
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引用次数: 0
A Rare Event at Birth: A Case Report of Multiple Cranial Nerve Palsy 出生时罕见事件:多发性脑神经麻痹1例报告
Pub Date : 2019-06-06 DOI: 10.24966/ncp-878x/100027
C. Cardoso
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引用次数: 0
Bacteriological Profile of Neonates Admitted with Suspected Sepsis in NICU of Tertiary Care Hospital of Western Nepal 尼泊尔西部三级医院新生儿重症监护病房疑似脓毒症新生儿的细菌学分析
Pub Date : 2019-06-06 DOI: 10.24966/ncp-878x/100031
B. Gupta
Septicemia in neonates refers to generalized bacterial infection documented by positive blood culture in the first four weeks of life and is one of the four leading causes of neonate’s mortality. To study and identify the bacterial etiologic agents responsible for neonatal sepsis and to determine the susceptibility pattern of isolates in a tertiary care hospital in Universal College of Medical Sciences and Teaching Hospital (UCMS-TH). The pathogens most often implicated in neonatal sepsis in developing countries differ from those seen in developed countries. clinically suspected cases of neonatal sepsis admitted to Neo- natal Intensive Care Unit (NICU) from Jan 2019 - April 2019 included in the study. The data were analyzed statistically. Two hun-dred ninety six blood samples were collected and processed from patients in accordance with international or less than 5000/cumm, platelets count less than 150000/cumm, band neutrophil ratio more than 0.2, absolute neutrophil count, C-reactive protein positive (more than 1 mg/dl), micro ESR > 15 mm/hr, blood cultures and sensitivity by standard methods.
新生儿败血症是指在生命的头四周内血液培养阳性记录的全身性细菌感染,是新生儿死亡的四大主要原因之一。目的:研究和鉴定导致新生儿脓毒症的细菌病原,并确定三级医院中分离物的药敏模式。发展中国家新生儿败血症中最常见的病原体与发达国家不同。2019年1月至2019年4月入住新生儿重症监护病房(NICU)的临床疑似新生儿脓毒症病例纳入研究。对数据进行统计学分析。按照国际标准或小于5000/cumm,血小板计数小于150000/cumm,带中性粒细胞比大于0.2,绝对中性粒细胞计数,c反应蛋白阳性(大于1mg /dl),微ESR > 15mm /hr,血培养和敏感性,收集和处理患者血样96份。
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引用次数: 1
The Successful Management of a Breast-Feeding Type 1 Diabetic Infant 1例母乳喂养1型糖尿病婴儿的成功治疗
Pub Date : 2019-06-06 DOI: 10.24966/ncp-878x/100032
J. Tung
Management of infants with type 1 diabetes is challenging to both the families and the medical team. In general, they have unpre- dictable oral intake and activity level, limited ability to express their needs, and low insulin requirement demanding more precise adjust- ment. We report a breast-feeding infant with multiple food allergies and type 1 diabetes managed smoothly with insulin pump and continuous glucose monitoring system.
婴儿1型糖尿病的管理对家庭和医疗团队都是一个挑战。一般来说,他们的口服摄入量和活动水平难以预测,表达自身需求的能力有限,胰岛素需求较低,需要更精确的调节。我们报告了一位患有多种食物过敏和1型糖尿病的母乳喂养婴儿,通过胰岛素泵和连续血糖监测系统顺利控制。
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引用次数: 0
Pleural Effusion as a Complication of Umbilical Venous Catheter 胸腔积液作为脐静脉导管的并发症
Pub Date : 2018-12-20 DOI: 10.24966/NCP-878X/100026
Sara M Rocha
Umbilical Venous Catheterization (UVC) is a common practice in neonatal units, though not without risks. Complications may occur in over 20% of patients; however pleural effusion is extremely rare. We report a case of an extreme preterm male neonate weighing 810 g, who developed pleural effusion due to malpositioned UVC. Pleural fluid was biochemically similar to parenteral nutrition solution. This alongside with the absence of recurrence of pleural effusion after UVC removal, support the causality between the UVC and pleural effusion. This case emphasizes the need to confirm the correct positioning of UVC. When in doubtful position, it should be withdrawn as early as possible, ensuring an alternative central access. If the clinical situation does not allow it, it is important to consider the osmolarity of the perfused solution, due to the risk of endothelial damage.
脐静脉置管(UVC)是一种常见的做法,在新生儿单位,虽然不是没有风险。超过20%的患者可能出现并发症;然而,胸腔积液极为罕见。我们报告一例极端早产男婴体重810克,谁发展胸膜积液由于错位UVC。从生化角度看,胸膜液与肠外营养液相似。这与UVC切除后没有复发的胸腔积液一起,支持了UVC和胸腔积液之间的因果关系。本案例强调了确认UVC正确定位的必要性。当处于可疑位置时,应尽早撤出,以确保另一个中央通道。如果临床情况不允许,考虑灌注溶液的渗透压是很重要的,因为有内皮损伤的风险。
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引用次数: 0
期刊
Journal of clinical pediatrics and neonatology
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