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Smokeless Tobacco: Pattern and Awareness in a Rural Area of Bangladesh 无烟烟草:孟加拉国农村地区的模式和认识
Pub Date : 2022-06-30 DOI: 10.3329/jcmcta.v33i1.67418
Tamanna Zahur, R. Parvin
Background: Smokeless tobacco consumption has contributed nothing except diseases, disability and death. But assessment of awareness and knowledge regarding its use has less been studied to the extent as that of smoking. The study was undertaken to assess the pattern of use and awareness of smokeless tobacco among rural community. Materials and methods: This descriptive cross-sectional study was conducted among 310 respondents selected through systemic sampling method, aged 18 years, residing at least for 10 years in Noakhali district in Bangladesh. This study was conducted from May to November 2013. Data were collected with a pretested questionnaire through face-to-face interview.  Results: Smokeless Tobacco (SLT) use was prevalent among 45.8% of respondents. Higher proportion of females than males used SLT. Zarda was the common form in more than half of the users. Among daily users, self-interest was the main factor for initiation and mean age of starting was 35 years.  Per day frequency of SLT use for 1-8 times was in two-thirds of the daily users. Most of the respondents knew that SLT is injurious to health. About two-thirds of them mentioned SLT as addictive. More than one-thirds of the respondents had knowledge that smoking is more injurious than SLT. However, 30% of the respondents knew that both smoking and SLT were equally addictive. Excluding the former users, majority of the respondents knew that SLT might be quitted.   Conclusion: Multistage effective behavioral change intervention programs are the preferable way to overcome this lifestyle-related health problem. JCMCTA 2022 ; 33 (1) : 166-172
背景:无烟烟草消费除了造成疾病、残疾和死亡外,没有任何其他因素。但是,对其使用的意识和知识的评估却很少像对吸烟的研究那样深入。进行这项研究是为了评估农村社区对无烟烟草的使用模式和认识。材料和方法:本描述性横断面研究在通过系统抽样方法选择的310名受访者中进行,年龄为18岁,在孟加拉国Noakhali地区居住至少10年。本研究于2013年5月至11月进行。通过面对面访谈,采用预测问卷收集数据。结果:45.8%的被调查者使用无烟烟草。女性使用SLT的比例高于男性。超过一半的用户使用的是Zarda格式。在日常用户中,自我利益是开始的主要因素,平均开始年龄为35岁。三分之二的日常使用者每天使用SLT的频率为1-8次。大多数受访者都知道SLT有害健康。大约三分之二的人认为SLT会上瘾。超过三分之一的受访者知道吸烟比吸烟危害更大。然而,30%的受访者知道吸烟和SLT同样会上瘾。除以前的使用者外,大部分受访者知道可能会戒掉SLT。结论:多阶段有效的行为改变干预方案是克服这种生活方式相关健康问题的较好方法。Jcmcta 2022;33 (1): 166-172
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引用次数: 0
Retrospective Analysis of Neck Masses Diagnosed by Histopathology from Chattogram General Hospital chtogram总医院组织病理学诊断颈部肿块的回顾性分析
Pub Date : 2022-06-30 DOI: 10.3329/jcmcta.v33i1.66915
Pankaj Chowdhury, A.K. Ahmed, SM Tareq Uddin Ahmed, Rabiul Alam Md Erfan Uddin, S. Biswas
Background: Neck masses are found in all age groups from many causes, ranging from congenital to acquired pathology. There is a wide variation in the presentation of neck masses concerning its site of origin, clinical presentation, and the nature of the progression of the disease. This study was performed to have an idea about the prevalence of various neck masses according to age and sex so that it would help us in diagnosing the neck masses. Materials and methods: This retrospective study was performed in the Department of Otolaryngology and Head Neck Surgery, Chattogram General Hospital, Chattogram from July 2018 and June 2019, over 97 patients presented with neck mass.  Results: Of 97 cases 69.1% were female and range from 7-77 years. The maximum case holding age group was 21- 30 years (26.8%). The histopathological diagnosis of the neck masses was inflammatory in 68 (70.1%), congenital in 5 (5.2%) and neoplastic in 24 (24.7%) cases. Chronic granulomatous lymphadenitis was the most common inflammatory lesion (50.5%) and a branchial cyst was the most common congenital mass (2.2%). Neoplastic masses were malignant in 10 (10.3%) and benign in 14 (14.4%) cases. The most common malignant neoplastic mass was a follicular carcinoma (6.2%), and the most common benign neoplastic mass was goitre (12.4%).  Conclusions: Cervical lymphadenopathy was the most commonly encountered neck mass. Most of the neck masses are benign. Out of these cervical lymph nodes, tubercular lymphadenopathy was most common.JCMCTA 2022 ; 33 (1) : 21-24
背景:颈部肿块可以在所有年龄组中发现,原因多种多样,从先天性到后天性。颈部肿块的表现有很大的差异,包括其起源部位、临床表现和疾病进展的性质。这项研究是为了了解不同年龄和性别的颈部肿块的患病率,以便帮助我们诊断颈部肿块。材料与方法:回顾性研究于2018年7月至2019年6月在Chattogram总医院耳鼻喉头颈外科进行,共97例颈部肿块患者。结果:97例患者中,女性占69.1%,年龄7 ~ 77岁。病例持有年龄以21 ~ 30岁最多(26.8%)。颈部肿块的组织病理学诊断为炎性68例(70.1%),先天性5例(5.2%),肿瘤性24例(24.7%)。慢性肉芽肿性淋巴结炎是最常见的炎性病变(50.5%),鳃裂囊肿是最常见的先天性肿块(2.2%)。肿瘤肿块10例(10.3%)为恶性,14例(14.4%)为良性。最常见的恶性肿瘤肿块为滤泡癌(6.2%),最常见的良性肿瘤肿块为甲状腺肿(12.4%)。结论:颈部淋巴结病是最常见的颈部肿块。大多数颈部肿块是良性的。在这些颈部淋巴结中,结节性淋巴结病最为常见。Jcmcta 2022;33 (1): 21-24
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引用次数: 0
Functional Outcome of Proximal Fibular Osteotomy in Medial Compartment Osteoarthritis of The Knee Joint 腓骨近端截骨术治疗膝关节内隔骨关节炎的功能效果
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.67201
C. Das, Md Mizanur Rahman Chowdhury, Saikat Ghosh, Mohammad Qausarul Matin, Md Nazrul Islam Choudhuri, Md Somirul Islam
Background: Proximal Fibular Osteotomy (PFO) has been proposed as a new surgical option for pain relief in patients with medial compartment knee osteoarthritis. It is simple, safe and affordable. To assess functional outcome of proximal fibular osteotomy in medial compartment osteoarthritis of knee joint. Materials and methods: This prospective hospital based clinical trial was carried out in the Department of Orthopedic Surgery Chittagong Medical College Hospital (CMCH) Chattogram from July 2019 to June 2020. A total of 30 patients with knee osteoarthritis were enrolled through inclusion and exclusion criteria by purposive sampling. Proximal fibular osteotomy was done after taking written informed consent. Data was recorded in a predesigned case record form. All the patients were followed up to 6 months when final outcome was assessed by Oxford Knee Score. All the data were analyzed statistically by using Statistical Package for Social Sciences (SPSS-25). The result was expressed as frequency, percentage and mean ± SD. Level of significance was calculated at p<0.05. Results: In this study, out of 30 cases, majority of the cases (57.7%) was in 55-64 years of age group. Mean ± SD pre-operative and post-operative VAS score were 7.13 ± 1.408 and 2.10 ± 0.803 respectively. According to Oxford Knee Score (OKS) pre-operative and postoperative mean ± SD were, 18.00 ± 2.117 and 36.53 ± 2.403. Mean ± SD pre-operative and post-operative Tibio Femoral Angle were 182.97 ± 1.810 and 178.63 ± 1.377 respectively. Mean ± SD pre-operative and post-operative Medial Joint Space (mm) were 1.223 ± 0.378 and 3.816 ± 0.982 respectively. Mean ± SD pre-operative and postoperative Lateral Joint Space (mm) were 6.640 ± 1.209 and 5.050 ± 0.897 respectively. Conclusion: After analyzing the results of present study, it can be concluded that proximal fibular osteotomy is a new, simple procedure in the management of medial compartment osteoarthritis of the knee which may delay the need for definitive knee procedures like unicompartmental knee arthroplasty or total knee replacement. JCMCTA 2021 ; 32 (2) : 137-141
背景:腓骨近端截骨术(PFO)已被提出作为一种新的手术选择来缓解内侧室膝骨关节炎患者的疼痛。它简单、安全、经济实惠。目的评价腓骨近端截骨术治疗膝关节内隔骨关节炎的功能效果。材料与方法:本前瞻性医院临床试验于2019年7月至2020年6月在吉大港医学院附属医院骨科进行。通过有目的的抽样,通过纳入和排除标准,共纳入30例膝骨关节炎患者。经书面知情同意后行腓骨近端截骨术。数据记录在预先设计的病例记录表格中。所有患者随访6个月,用牛津膝关节评分评估最终结果。所有数据采用SPSS-25统计软件包进行统计分析。结果以频率、百分比和平均值±SD表示。p<0.05为显著性水平。结果:本组30例病例中,以55 ~ 64岁年龄组居多(57.7%)。术前、术后VAS评分均值±SD分别为7.13±1.408分、2.10±0.803分。牛津膝关节评分(OKS)术前、术后平均±SD分别为18.00±2.117和36.53±2.403。术前、术后胫股角均值±SD分别为182.97±1.810和178.63±1.377。术前、术后内侧关节间隙(mm)均值±SD分别为1.223±0.378和3.816±0.982。术前、术后外侧关节间隙(mm)均值±SD分别为6.640±1.209和5.050±0.897。结论:通过对本研究结果的分析,可以得出结论,腓骨近端截骨术是治疗膝关节内侧室骨关节炎的一种新的、简单的手术方法,可以延迟单室膝关节置换术或全膝关节置换术等决定性膝关节手术的需要。Jcmcta 2021;32 (2): 137-141
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引用次数: 0
Knowledge, Attitude and Practice Regarding COVID-19 among Healthcare Workers in Chattogram, Bangladesh 孟加拉国Chattogram地区医护人员对COVID-19的知识、态度和做法
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.66498
M. K. Dutta, Bidduth Barua, Rahnuma Rubayat, H. Nasreen, Suman Biswas
Background: The coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease caused by the highly contagious novel coronavirus (SARS-CoV 2). COVID-19 pandemic continues to challenge healthcare services worldwide. Healthcare Workers (HCWs) are more susceptible to COVID-19 infection than the general population due to frequent contact with infected individuals. This study was aimed to assess the knowledge, attitude and practice among HCWs towards COVID-19 in some COVID dedicated hospitals of Chattogram, Bangladesh. Materials and methods: This descriptive cross-sectional study was conducted at three hospitals (Chittagong Medical College Hospital, Chattogram 250 Bed General Hospital, and Bangladesh Institute of Tropical and Infectious Disease) in Chattogram, from January 2021 to August 2021. The study included 393 HCWs (Physicians and nurses) by a non-probability convenient sampling method. An interview administered questionnaire was used to evaluate their knowledge, attitude and practices regarding COVID-19 and their associations with the participants’ characteristics. Results: Participants were predominantly female (230/393, 58.0%) and physicians (313/393, 77.0%). Almost all had sufficient knowledge (85.8%) and good preventive practice (92.1%) towards COVID-19, however, there was also a rather low level of positive attitude recorded, at 69.0%. Factors associated with KAP were, Knowledge: being a physician and higher education. Attitude: age >40 years, Practice: being a physician. Conclusion: The findings demonstrated sufficient knowledge and good preventive practice towards COVID-19, however, positive attitude was lower. Therefore, it is an identified requirement to continue with additional education and training strategies to offer a positive viewpoint of the pandemic for all HCWs. JCMCTA 2021 ; 32 (2) : 79-84
背景:2019冠状病毒病(COVID-19)是由高度传染性的新型冠状病毒(SARS-CoV 2)引起的一种大流行呼吸道疾病。COVID-19大流行继续对全球卫生保健服务构成挑战。由于经常与感染者接触,卫生保健工作者比一般人群更容易感染COVID-19。本研究旨在评估孟加拉国Chattogram部分COVID-19专科医院医护人员对COVID-19的知识、态度和做法。材料和方法:本描述性横断面研究于2021年1月至2021年8月在Chattogram的三家医院(吉大港医学院医院、Chattogram 250床位总医院和孟加拉国热带和传染病研究所)进行。本研究采用非概率方便抽样方法,纳入393名HCWs(医生和护士)。采用访谈问卷评估他们对COVID-19的知识、态度和做法及其与参与者特征的关联。结果:参与者以女性(230/393,58.0%)和医生(313/393,77.0%)为主。几乎所有人都对新冠肺炎有足够的知识(85.8%)和良好的预防措施(92.1%),但积极态度也很低,为69.0%。与KAP相关的因素是:知识:成为医生和高等教育。态度:年龄>40岁,职业:医师。结论:调查结果显示,受访学生对新冠肺炎的认知和预防措施充足,但积极态度较低。因此,确定需要继续实施额外的教育和培训战略,向所有卫生保健工作者提供关于大流行病的积极观点。Jcmcta 2021;32 (2): 79-84
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引用次数: 0
Evaluation of Antithyroid Antibodies in Polycystic Ovarian Syndrome of Reproductive Women 生殖期妇女多囊卵巢综合征抗甲状腺抗体的评价
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.66514
S. Akhter, N. Tasnim, Mohammed Hafizul Islam, Pervin Akter, Pijush Karmakar, Ummey Salma
Background: Polycystic Ovarian Syndrome (PCOS) is common but a treatable cause of infertility in reproductive women. Thyroid hormone abnormality is commonly seen in Polycystic Ovarian Syndrome of reproductive women. Antithyroid antibodies have been detected in women with PCOS. The aim of the present study is to evaluate the antithyroid antibodies in Polycystic Ovarian Syndrome (PCOS) of reproductive women. Materials and methods: A hospital based cross-sectional comparative study was conducted in the outpatient Department of Obstetrics and Gynaecology in CMCH, Institute of Nuclear Medicine and Allied Subject and the Department of Biochemistry in CMC. Eighty (80) PCOS women diagnosed by ultrasonography were taken by nonprobability convenient sampling, considered as group A and another twenty (20) healthy women were taken, considered as group B. Important variables in this study were serum anti-TPO antibody, anti-Tg antibody, TSH, age, menstrual history, hirsutism, waist circumference and BMI. Results: This study revealed a statistically significant higher prevalence of autoimmune thyroiditis in PCOS cases in comparison to healthy group (32.5 % and 37.5% patients had increased anti-TPO and anti-Tg antibodies respectively). Mean serum anti-TPO and anti-Tg antibodies were increased significantly in PCOS cases than that of healthy women group. Mean serum TSH was not increased significantly in PCOS cases than that of healthy group.52.5%, 47.5% patients had oligomenorrhea and amenorrhea respectively, 21.2% had hirsutism, 68.8% cases were overweight & obese and 77.5% were central obese.  Conclusion: High prevalence of thyroid autoimmunity in euthyroid PCOS patients refers to the importance of screening not only thyroid hormone levels but also thyroid antibody level during the investigation of PCOS of reproductive women and thereby early diagnosis and management of infertility associated with PCOS. JCMCTA 2021 ; 32 (2) : 105-110
背景:多囊卵巢综合征(PCOS)是一种常见但可治疗的育龄妇女不孕原因。甲状腺激素异常常见于生殖期妇女多囊卵巢综合征。在多囊卵巢综合征患者中检测到抗甲状腺抗体。本研究的目的是评估多囊卵巢综合征(PCOS)育龄妇女的抗甲状腺抗体。材料与方法:采用以医院为单位的横断面对比研究,分别在中医医院妇产科门诊、核医学及相关学科研究所、生物化学系进行对比研究。采用非概率方便抽样法,选取超声诊断为PCOS的女性80例作为A组,选取健康女性20例作为b组。本研究的重要变量为血清抗tpo抗体、抗tg抗体、TSH、年龄、月经史、多毛、腰围、BMI。结果:本研究显示,与健康组相比,PCOS患者自身免疫性甲状腺炎的患病率有统计学意义(32.5%和37.5%的患者抗tpo和抗tg抗体分别升高)。PCOS患者血清抗tpo抗体和抗tg抗体均明显高于正常对照组。PCOS患者血清TSH均值较健康组无明显升高,经少、闭经分别为52.5%、47.5%,多毛21.2%,超重肥胖68.8%,中心性肥胖77.5%。结论:正常甲状腺型多囊卵巢综合征患者甲状腺自身免疫发生率高,说明在调查生殖期妇女多囊卵巢综合征时,不仅要筛查甲状腺激素水平,还要筛查甲状腺抗体水平,以便早期诊断和治疗多囊卵巢综合征相关不孕。Jcmcta 2021;32 (2): 105-110
{"title":"Evaluation of Antithyroid Antibodies in Polycystic Ovarian Syndrome of Reproductive Women","authors":"S. Akhter, N. Tasnim, Mohammed Hafizul Islam, Pervin Akter, Pijush Karmakar, Ummey Salma","doi":"10.3329/jcmcta.v32i2.66514","DOIUrl":"https://doi.org/10.3329/jcmcta.v32i2.66514","url":null,"abstract":"Background: Polycystic Ovarian Syndrome (PCOS) is common but a treatable cause of infertility in reproductive women. Thyroid hormone abnormality is commonly seen in Polycystic Ovarian Syndrome of reproductive women. Antithyroid antibodies have been detected in women with PCOS. The aim of the present study is to evaluate the antithyroid antibodies in Polycystic Ovarian Syndrome (PCOS) of reproductive women. \u0000Materials and methods: A hospital based cross-sectional comparative study was conducted in the outpatient Department of Obstetrics and Gynaecology in CMCH, Institute of Nuclear Medicine and Allied Subject and the Department of Biochemistry in CMC. Eighty (80) PCOS women diagnosed by ultrasonography were taken by nonprobability convenient sampling, considered as group A and another twenty (20) healthy women were taken, considered as group B. Important variables in this study were serum anti-TPO antibody, anti-Tg antibody, TSH, age, menstrual history, hirsutism, waist circumference and BMI. \u0000Results: This study revealed a statistically significant higher prevalence of autoimmune thyroiditis in PCOS cases in comparison to healthy group (32.5 % and 37.5% patients had increased anti-TPO and anti-Tg antibodies respectively). Mean serum anti-TPO and anti-Tg antibodies were increased significantly in PCOS cases than that of healthy women group. Mean serum TSH was not increased significantly in PCOS cases than that of healthy group.52.5%, 47.5% patients had oligomenorrhea and amenorrhea respectively, 21.2% had hirsutism, 68.8% cases were overweight & obese and 77.5% were central obese. \u0000 Conclusion: High prevalence of thyroid autoimmunity in euthyroid PCOS patients refers to the importance of screening not only thyroid hormone levels but also thyroid antibody level during the investigation of PCOS of reproductive women and thereby early diagnosis and management of infertility associated with PCOS. \u0000JCMCTA 2021 ; 32 (2) : 105-110","PeriodicalId":93458,"journal":{"name":"Journal of Chittagong Medical College Teachers' Association","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87487270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Blood Pressure with Overweight in Young Adult Student 青少年学生血压与超重的关系
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.66447
Debjanee Barua, N. Noor, M. Begum, Shahin Akhter, Shuvramoy Barua, Nilima Jafrin
Background: Obesity and overweight in young adult is rising & its deleterious health hazard is becoming a major threat now a days. It is one of the major public health problems globally. Overweight may cause metabolic and endocrinological changes. If untreated, hypertension, cardiovascular disease, hyperglycemia, dyslipidemia, atherosclerosis, metabolic syndrome, cancer may occur. Hypertension is more common in obese and overweight people. This study aimed to observe the association of blood pressure with overweight in young adult students. Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram. Total 120 students, aged between 18-24 years were included in the study. 60 young adult students with a Body Mass Index (BMI) of 25- 29.9kg/m2 were included in case group as overweight subject and 60 students of same age with a BMI of 18.5- 24.9kg/m2 were taken as a control group. General physical examination was done, anthropometric measurements- Height, weight, BMI and pulse, systolic blood pressure and diastolic blood pressure were measured. Pulse Pressure (PP) and mean arterial pressure were calculated. For statistical analysis unpaired student’s ‘t’ test, chisquare test and correlation coefficient were done by using SPSS for windows version-25. Results: Systolic Blood Pressure (SBP) Diastolic Blood Pressure (DBP) and Mean Arterial Pressure (MAP) were significantly high in overweight (Case) students (p<0.001). Frequency of prehypertension was more in overweight group (p<0.001) comparing to normal weight group. Significant positive correlations (p<0.05) were observed among BMI with SBP, DBP and MAP in overweight young adult students. Conclusion: According to present results it was concluded that apparently healthy overweight young adult students were associated with increased blood pressure than normal weight students. JCMCTA 2021 ; 32 (2) : 47-52
背景:年轻人的肥胖和超重正在上升,其有害的健康危害正在成为当今的主要威胁。它是全球主要的公共卫生问题之一。超重可能会导致代谢和内分泌方面的变化。如果不及时治疗,可能会发生高血压、心血管疾病、高血糖、血脂异常、动脉粥样硬化、代谢综合征、癌症。高血压在肥胖和超重人群中更为常见。本研究旨在观察青年大学生血压与超重的关系。材料与方法:本病例对照研究在吉大港医学院生理学系进行。共有120名年龄在18-24岁之间的学生参与了这项研究。病例组为体重指数(BMI)在25 ~ 29.9kg/m2之间的青年大学生60名,作为超重组;对照组为体重指数在18.5 ~ 24.9kg/m2之间的同龄大学生60名。一般体格检查,人体测量-身高,体重,身体质量指数和脉搏,收缩压和舒张压测量。计算脉压(PP)和平均动脉压。统计分析采用SPSS软件(windows version-25)进行未配对学生t检验、齐方检验和相关系数分析。结果:超重学生(Case)的收缩压(SBP)、舒张压(DBP)和平均动脉压(MAP)均较高(p<0.001)。超重组高血压前期发生频率高于正常体重组(p<0.001)。体重超重青年学生BMI与收缩压、舒张压、MAP呈显著正相关(p<0.05)。结论:根据目前的研究结果,可以得出明显健康超重的青少年学生比正常体重的学生血压升高的相关结论。Jcmcta 2021;32 (2): 47-52
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引用次数: 0
Modified Bentall’s Procedure for Aortic Root Aneurysm : A Case Report 改良本特尔手术治疗主动脉根动脉瘤1例报告
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.67620
S. Gupta, M. Hoque, Bhabesh C Mandol, Md. Ashraful Islam, P. Chanda
Background: The modified Bentall(M Bentall) procedure is considered as the gold standard for patients requiring aortic root replacement, where the native aortic valve is required to be replaced. Case Presentation: We hereby present a case report of a patient who was diagnosed having moderate to severe Aortic Regurgitation (AR) with aortic root aneurysm. He was treated successfully by us with the M.Bentall procedure. Conclusion: As the aortic disease detection and surgical expertise improved in our country, a M.Bentall procedure is a suitable and safe treatment option for Aortic root aneurysm. JCMCTA 2021 ; 32 (2) : 147-150
背景:改良的Bentall(M Bentall)手术被认为是需要主动脉根部置换术的患者的金标准,在这些患者中,需要更换原有的主动脉瓣。病例报告:我们在此提出一个病例报告的病人谁被诊断为中度至重度主动脉反流(AR)与主动脉根动脉瘤。我们用M.Bentall手术成功地治疗了他。结论:随着我国主动脉疾病检测水平和手术技术水平的提高,m.b etall手术是治疗主动脉根动脉瘤的一种安全可行的方法。Jcmcta 2021;32 (2): 147-150
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引用次数: 0
Assessment of Neurodevelopmental Status and Risk Factors for Adverse Neurodevelopmental Outcome in Late Preterm Infants at 6 Months Corrected Age : An Prospective Observational Study 6个月矫正龄晚期早产儿神经发育状况和不良神经发育结局危险因素评估:一项前瞻性观察研究
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.66496
Tanjina Hoq, P. Chowdhury, Sanat Kumar Barua, S. Hasan, Suman Biswas, M. Datta, Fannana Ahmed
Background: Late Preterm (LP) infants, previously considered low risk, have been identified to be at risk of developmental problems in infancy and early childhood. There is limited information on the outcome of these infants in low and middle income countries. This study was aimed to assess the neurodevelopmental status of LP born neonates and to determine factors associated with adverse neurodevelopmental outcome in a tertiary hospital of Chattogram, Bangladesh. Materials and methods: In this prospective observational study, 108 LP (34 to <37 completed weeks gestation at birth) infants were enrolled from the Special Care Neonatal Unit (SCANU) Chittagong Medical College Hospital (CMCH) from June 2018 to May 2019. Neurodevelopmental assessment was done by Rapid Neurodevelopmental Assessment (RNDA) at 1, 3, and 6 months of Corrected Age (CA). Results: Of the 108 enrolled children, 30 (27.8%) attended all 3 follow-up, 69 (63.9%) had incomplete follow-up, and 9 (8.3%) died. At final follow-up, out of 30 infants, 25 (83.3%) had no abnormality in all 8 domains of RNDA. Three infants (10.0%) had abnormalities in one domain and 2 (6.7%) had abnormalities in 5 domains. Gross motor abnormality was most common abnormality (13.4%), followed by speech (10.0%), and cognition (6.7%). Small for gestational age was found to be the only independent predictive factor for Neurodevelopmental Abnormality (NDA) in LP infants. Conclusion: This study demonstrates that 16.7% of the LP infants had evidence of neurodevelopmental impairment at 6 months of corrected age. SGA was an important risk factor of adverse neurodevelopmental outcome. Thus, LP infants in Bangladesh require long-term follow-up to monitor developmental outcome. JCMCTA 2021 ; 32 (2) : 70-74
背景:晚早产儿(LP),以前被认为是低风险的婴儿,已经被确定在婴儿期和幼儿期有发育问题的风险。关于这些婴儿在低收入和中等收入国家的结局的信息有限。本研究旨在评估LP出生新生儿的神经发育状况,并确定与孟加拉国Chattogram三级医院不良神经发育结果相关的因素。材料和方法:在这项前瞻性观察性研究中,2018年6月至2019年5月,在吉大港医学院附属医院(CMCH)新生儿特护病房(SCANU)招募了108名LP(出生时妊娠34至<37周)婴儿。在矫正年龄(CA) 1、3、6个月时采用快速神经发育评估(RNDA)进行神经发育评估。结果:108名入组儿童中,30名(27.8%)参加了全部3次随访,69名(63.9%)随访不完全,9名(8.3%)死亡。在最后的随访中,在30名婴儿中,25名(83.3%)在RNDA的所有8个区域没有异常。3例(10.0%)患儿1个结构域异常,2例(6.7%)患儿5个结构域异常。以大运动异常最为常见(13.4%),其次为言语异常(10.0%)和认知异常(6.7%)。发现胎龄小是LP婴儿神经发育异常(NDA)的唯一独立预测因素。结论:本研究表明16.7%的LP婴儿在矫正年龄6个月时存在神经发育障碍的证据。SGA是不良神经发育结局的重要危险因素。因此,孟加拉国的LP婴儿需要长期随访以监测发育结果。Jcmcta 2021;32 (2): 70-74
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引用次数: 0
Association of Glycosylated Albumin Level with Gestational Diabetes Mellitus 糖化白蛋白水平与妊娠期糖尿病的关系
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.66495
F. Islam, R. K. Kazal, Nadira Haque, N. Hosain, Badrunnahar Rumi, Keya Debnath, Ruma Akter, Marjiara Begum, Farhan Akhter
Background: Gestational Diabetes Mellitus (GDM) is a common medical disorder detected during pregnancy with adverse consequences on the health of the mother and the fetus. Glycosylated hemoglobin (HbA1c) is an important parameter of glycemic control in patients with diabetes mellitus. However, it only reflects the long-term glycemic status, but can’t reflect short term glycemic control. It has also been demonstrated that HbA1c does not reflect glycemic control accurately during pregnancy because of iron deficiency. But Glycosylated Albumin (GA) reflects average blood glucose within 2-3 weeks and is not influenced by iron deficiency. Therefore, glycosylated albumin may be used to measure recent changes in blood glucose level in GDM patients. The aim of the study is to evaluate the association of glycosylated albumin and glycemic status in GDM. Materials and methods: This case control study was carried out in the Department of Obstetrics & Gynecology, Bangabandhu Sheikh Mujib Medical University, BSMMU, Dhaka between August 2017 and December 2018. Atotal of 140 pregnant women between 18-35 years of age attending outdoor antenatal clinic in their second and third trimester of pregnancy were enrolled in this study. Among them 70 diagnosed case of GDM were considered as group I and rest 70 non-diabetic pregnant women were considered as control and group II. Plasma glycosylated albumin was measured in all of these patients. Statistical analysis of the results was obtained by using Windows based computer software devised with Statistical Packages for Social Sciences (SPSS-22). Results: The mean glycosylated albumin was 17.12±2.00 (%) in group I and 12.90±1.03 (%) in group II. The difference was statistically significant (p<0.05) between two groups. There was a positive significant moderate correlation (r=0.643, p=0.001) between glycosylated albumin (%) and 2 hours after 75 gm glucose in GDM patients. There was also a positive significant weak correlation (r=0.258, p=0.031) between GA and FBS in GDM patients. Conclusion: A significant positive association was found between glycemic status in GDM and maternal glycosylated albumin levels. Therefore,glycosylated albumin may be applied to reflect the average blood glucose status in pregnant women with GDM. JCMCTA 2021 ; 32 (2) : 64-69
背景:妊娠期糖尿病(GDM)是妊娠期间发现的一种常见的医学疾病,对母亲和胎儿的健康有不良影响。糖化血红蛋白(HbA1c)是糖尿病患者血糖控制的重要指标。但是,它只能反映长期血糖状态,不能反映短期血糖控制情况。也有研究表明,由于缺铁,妊娠期HbA1c不能准确反映血糖控制情况。但糖基化白蛋白(GA)反映2-3周内的平均血糖,不受缺铁的影响。因此,糖基化白蛋白可用于测量GDM患者近期血糖水平的变化。该研究的目的是评估糖基化白蛋白与GDM血糖状态的关系。材料与方法:本病例对照研究于2017年8月至2018年12月在达卡Bangabandhu Sheikh Mujib医科大学妇产科进行。共有140名年龄在18-35岁之间的孕妇在妊娠中期和晚期在室外产前诊所接受了这项研究。其中诊断为GDM的孕妇70例作为第一组,其余70例非糖尿病孕妇作为对照组和第二组。所有患者均测量了血浆糖化白蛋白。采用SPSS-22 (Statistical Packages for Social Sciences)软件对结果进行统计分析。结果:ⅰ组平均糖化白蛋白为17.12±2.00(%),ⅱ组平均糖化白蛋白为12.90±1.03(%)。两组间差异有统计学意义(p<0.05)。GDM患者糖基化白蛋白(%)与75 gm葡萄糖后2小时呈正相关(r=0.643, p=0.001)。GDM患者GA与FBS之间也存在显著正相关(r=0.258, p=0.031)。结论:GDM患者血糖状态与母体糖基化白蛋白水平呈正相关。因此,糖基化白蛋白可用于反映妊娠期糖尿病孕妇的平均血糖状态。Jcmcta 2021;32 (2): 64-69
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引用次数: 0
Clinico-epidemiological Study on Self-induced Poisoning Caused by Substances Other than Organophosphorus Compound 非有机磷化合物所致自致中毒的临床流行病学研究
Pub Date : 2021-12-31 DOI: 10.3329/jcmcta.v32i2.66445
I. Ara, Rabiul Alam Md Erfan Uddin, A. Ghose
Background: Though Organophosphorus Compounds (OPC) are mostly used for self-induced poisoning, non- OPC poisoning cases are increasing day by day. This study was done to describe clinical pattern and outcome of poisoning other than OPC.  Materials and methods: This observational study was conducted in the Medicine Ward of Chittagong Medical College Hospital. Data were collected in structured case record forms. Total 204 patients (n=204) were included in the study after fulfilling the inclusion criteria. Data were analyzed with SPSS and expressed as percentage, mean with standard deviation as appropriate. Results: Out of 204 patients, most were female (60.8%). Most of the patients were young, 56.9% patients were unmarried, 60.8% poisoned patients resided in metropolitan area, most were with low educational level, 57.4% patients came from the middle class socioeconomic group, 82.4% patients were poisoned by a single agent and 17.6% by multiple agents. Offending agents were identified in 96.6% cases. Poisoning by drugs was the highest (47.1%) followed by rat killer poisoning (22.5%) poisoning by non-OPC insecticides (6.9%) corrosive poisoning (6.4%) chemical poisoning (3.9%) and alcohol poisoning (1%). Family disharmony was the underlying cause of self-harm in 47.1% cases, financial constraints in 8.3%, social crisis in 7.8%, failure in love affairs in 6.4% and academic failure in 2.5% patients. 14.7% patients poisoned themselves to gain some benefit by the act of self-harm. 81.4% patients were discharged with advice, 2.9% died. Conclusion: Burden of Non-OPC poisoning is high. Outcome is not so fatal as OPC, but the problem has to be addressed in large scale. JCMCTA 2021 ; 32 (2) : 34-40
背景:有机磷化合物(OPC)中毒多用于自致中毒,但非OPC中毒病例日益增多。本研究是为了描述除OPC以外的中毒的临床模式和结果。材料与方法:本观察性研究在吉大港医学院附属医院内科病房进行。数据以结构化的病例记录表格收集。在满足纳入标准后,共纳入204例患者(n=204)。数据采用SPSS统计软件进行分析,以百分比表示,取平均值,标准差适当。结果:204例患者中,女性居多(60.8%)。患者以年轻人居多,未婚占56.9%,60.8%的患者居住在大城市,文化程度较低,57.4%的患者来自中产阶级社会经济群体,82.4%的患者为单一药物中毒,17.6%的患者为多种药物中毒。96.6%的病例中发现了违规物质。药物中毒最多(47.1%),其次是灭鼠剂中毒(22.5%)、非opc类杀虫剂中毒(6.9%)、腐蚀性中毒(6.4%)、化学中毒(3.9%)和酒精中毒(1%)。家庭不和谐是自残的根本原因,占47.1%,经济拮据占8.3%,社会危机占7.8%,恋爱失败占6.4%,学业失败占2.5%。14.7%的患者通过自残行为毒害自己以获得某种利益。81.4%的患者按建议出院,2.9%的患者死亡。结论:非opc中毒负担高。结果不像OPC那样致命,但问题必须大规模解决。Jcmcta 2021;32 (2): 34-40
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引用次数: 0
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Journal of Chittagong Medical College Teachers' Association
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