Pub Date : 2025-01-01Epub Date: 2025-07-21DOI: 10.1080/19338244.2025.2533774
Giuseppe La Torre, Andrea Bongiovanni, David Shaholli, Maria Vittoria Manai, Andrea De Giorgi, Danilo Iera, Leonardo Romano, Giuseppe Adamo, Michele Paolucci, Marco Carnì, Sabina Sernia, Simone De Sio
The aim of this study was assessing the impact of Ionizing radiation (IR) exposure on thyroid function and cancer risk over an 11-year follow-up period among healthcare workers. A retrospective cohort of 585 hospital workers in Rome was carried out. Workers were categorized based on IR exposure levels in the period 2010 - 2020. Survival analysis was conducted to assess the development of thyroid abnormalities and tumors. Exposed workers exhibited a higher risk of developing thyroid alterations, notably hypothyroidism and goiter (HR = 1.69, 95% CI 1.17- 2.43), and a reduced likelihood of developing cancer (HR = 0.24, 95% CI 0.09-0.64). Gender and age were significant risk factors for thyroid alterations, with females and older individuals exhibiting higher susceptibility. This study suggests an increased thyroid issues but reduced cancer rates among exposed to low-dose IR compared to unexposed peers, underscoring the need for further research to enhance occupational health.
本研究的目的是评估电离辐射(IR)暴露对医护人员甲状腺功能和癌症风险的影响,随访11年。对罗马585名医院工作人员进行了回顾性队列研究。工作人员根据2010年至2020年期间的红外暴露水平进行分类。通过生存分析来评估甲状腺异常和肿瘤的发展。暴露的工人患甲状腺病变的风险更高,特别是甲状腺功能减退和甲状腺肿(HR = 1.69, 95% CI 1.17- 2.43),患癌症的可能性降低(HR = 0.24, 95% CI 0.09-0.64)。性别和年龄是甲状腺病变的重要危险因素,女性和老年人表现出更高的易感性。这项研究表明,与未暴露的同龄人相比,暴露于低剂量红外辐射的人甲状腺问题增加,但癌症发病率降低,强调需要进一步研究以加强职业健康。
{"title":"Low-dose ionizing radiation and cancer risk, thyroid alteration in health professionals: A retrospective cohort study.","authors":"Giuseppe La Torre, Andrea Bongiovanni, David Shaholli, Maria Vittoria Manai, Andrea De Giorgi, Danilo Iera, Leonardo Romano, Giuseppe Adamo, Michele Paolucci, Marco Carnì, Sabina Sernia, Simone De Sio","doi":"10.1080/19338244.2025.2533774","DOIUrl":"10.1080/19338244.2025.2533774","url":null,"abstract":"<p><p>The aim of this study was assessing the impact of Ionizing radiation (IR) exposure on thyroid function and cancer risk over an 11-year follow-up period among healthcare workers. A retrospective cohort of 585 hospital workers in Rome was carried out. Workers were categorized based on IR exposure levels in the period 2010 - 2020. Survival analysis was conducted to assess the development of thyroid abnormalities and tumors. Exposed workers exhibited a higher risk of developing thyroid alterations, notably hypothyroidism and goiter (HR = 1.69, 95% CI 1.17- 2.43), and a reduced likelihood of developing cancer (HR = 0.24, 95% CI 0.09-0.64). Gender and age were significant risk factors for thyroid alterations, with females and older individuals exhibiting higher susceptibility. This study suggests an increased thyroid issues but reduced cancer rates among exposed to low-dose IR compared to unexposed peers, underscoring the need for further research to enhance occupational health.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"187-200"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-03-11DOI: 10.1080/19338244.2025.2473879
Yusuf Samir Hasanlı
Long-term night shift (NS) work is known to affect the body's circadian rhythm, leading to chronic low-level inflammation. We aimed to evaluate this information for the first time through CRP-Albumin Ratio [CAR] and Neutrophil-Lymphocyte Ratio [NLR] levels. Design is descriptive, cross-sectional. After exclusion criteria, a total of 84 males were included in the study, 38 of whom had been working at NS for at least three months and 46 who had been working on the day shift. Both NLR and CAR levels were significantly higher in NS workers compared to day shift workers (2.19 [%95 CI 1.99-2.39]; 1.84 [%95 CI 1.65-2.03] p = 0.012 and 0.44 [%95 CI 0.32-0.56]; 0.24 [%95 CI 0.18-0.29] p = 0.002, respectively). This supports the idea that chronic low inflammation may occur as a result of disruption of the circadian rhythm.
众所周知,长期夜班工作会影响身体的昼夜节律,导致慢性低水平炎症。我们的目的是首次通过crp -白蛋白比(CAR)和中性粒细胞-淋巴细胞比(NLR)水平来评估这一信息。设计是描述性的、横断面的。排除标准后,共有84名男性被纳入研究,其中38人在NS工作至少三个月,46人在白班工作。NS工人的NLR和CAR水平均显著高于白班工人(2.19 [%95 CI 1.99-2.39];1.84 [% 95 CI 1.65 - -2.03) p = 0.012和0.44 (% 95 CI 0.32 - -0.56);0.24 [% 95 CI 0.18 - -0.29), p = 0.002)。这支持了一种观点,即慢性低炎症可能是昼夜节律中断的结果。
{"title":"Assessment of inflammatory status in long-term night shift workers using the CRP-albumin ratio and neutrophil-lymphocyte ratio.","authors":"Yusuf Samir Hasanlı","doi":"10.1080/19338244.2025.2473879","DOIUrl":"10.1080/19338244.2025.2473879","url":null,"abstract":"<p><p>Long-term night shift (NS) work is known to affect the body's circadian rhythm, leading to chronic low-level inflammation. We aimed to evaluate this information for the first time through CRP-Albumin Ratio [CAR] and Neutrophil-Lymphocyte Ratio [NLR] levels. Design is descriptive, cross-sectional. After exclusion criteria, a total of 84 males were included in the study, 38 of whom had been working at NS for at least three months and 46 who had been working on the day shift. Both NLR and CAR levels were significantly higher in NS workers compared to day shift workers (2.19 [%95 CI 1.99-2.39]; 1.84 [%95 CI 1.65-2.03] <i>p</i> = 0.012 and 0.44 [%95 CI 0.32-0.56]; 0.24 [%95 CI 0.18-0.29] <i>p</i> = 0.002, respectively). This supports the idea that chronic low inflammation may occur as a result of disruption of the circadian rhythm.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-03-18DOI: 10.1080/19338244.2025.2480113
Jesús Gibran Hernández-Pérez, Abraham Valenzuela-Sánchez, David S López, Luisa Torres-Sánchez
We evaluated the association between urinary concentrations of phthalates/bisphenols mixtures and diabetes mellitus (DM) and poorly controlled DM, stratified by sex, and race/ethnicity in 2718 adults from the 2013 to 2016 National Health and Nutrition Examination Survey. DM was self-reported or defined by glucose tests/hypoglycemic use. Poorly controlled DM was defined by HbA1c ≥ 8%. Principal component analyses allowed to identify three mixtures: (1) DEHP (di(2-ethylhexyl) phthalate metabolites), (2) LMW/BPs (bisphenol A, F, S, and low molecular weight phthalates), and (3) high molecular weight phthalates. Group weighted quantile sum regression showed that the DEHP mixture was associated with lower DM prevalence in women and "other races" participants. Conversely, the LMW/BPs mixture was associated with higher DM odds, mainly among Mexican Americans. Race/ethnicity seems to determine the association between the different exposure mixtures and DM prevalence and poorly controlled DM.
{"title":"Racial/ethnic disparities in the association of environmental exposure to phthalates and bisphenols mixtures with diabetes mellitus: NHANES 2013-2016.","authors":"Jesús Gibran Hernández-Pérez, Abraham Valenzuela-Sánchez, David S López, Luisa Torres-Sánchez","doi":"10.1080/19338244.2025.2480113","DOIUrl":"10.1080/19338244.2025.2480113","url":null,"abstract":"<p><p>We evaluated the association between urinary concentrations of phthalates/bisphenols mixtures and diabetes mellitus (DM) and poorly controlled DM, stratified by sex, and race/ethnicity in 2718 adults from the 2013 to 2016 National Health and Nutrition Examination Survey. DM was self-reported or defined by glucose tests/hypoglycemic use. Poorly controlled DM was defined by HbA1c ≥ 8%. Principal component analyses allowed to identify three mixtures: (1) DEHP (di(2-ethylhexyl) phthalate metabolites), (2) LMW/BPs (bisphenol A, F, S, and low molecular weight phthalates), and (3) high molecular weight phthalates. Group weighted quantile sum regression showed that the DEHP mixture was associated with lower DM prevalence in women and \"other races\" participants. Conversely, the LMW/BPs mixture was associated with higher DM odds, mainly among Mexican Americans. Race/ethnicity seems to determine the association between the different exposure mixtures and DM prevalence and poorly controlled DM.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"49-61"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143660039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Rising temperatures and extreme weather pose a significant public health threat. Workers in low- and middle-income countries are particularly vulnerable to heat stress, which can lead to psychological repercussions, including climate anxiety. This study investigated the psychological impacts of heat stress and coping strategies among workers in relation to climate anxiety.
Method: A cross-sectional survey of 800 indoor and outdoor workers was conducted in 2024. Environmental heat stress was measured using a wet bulb globe temperature (WBGT) monitor, defining heat stress as exceeding task-specific threshold limits. Heat strain indicators (HSIs) such as core body temperature (CBT) and urine specific gravity (USG) were assessed alongside perceived heat stress and psychological impacts using a validated HOTHAPS questionnaire.
Results: The WBGT exceeded recommended limits for 62% of workers (30.3 ± 5.0 °C). Among heat-exposed workers, 80% reported heat-related health symptoms, with a significant rise in HSIs, including CBT (AOR = 1.9; 95% CI: 1.4-2.7). Psychological symptoms were prevalent in 94% of exposed workers, with heightened risks of climate anxiety (AOR = 2.8), stress (AOR = 2.7), and mental fatigue (AOR = 3.7). Women and summer months showed greater vulnerability.
Conclusion: Heat stress significantly affects psychological well-being among South Indian workers. Protective workplace policies are crucial to mitigating climate-induced psychological impacts.
{"title":"Climate induced heat stress and its psychological effects among South Indian workers.","authors":"Gayathri Kg, Vijayalakshmi P, Krishnan S, Rekha S, Vidhya Venugopal","doi":"10.1080/19338244.2025.2545778","DOIUrl":"10.1080/19338244.2025.2545778","url":null,"abstract":"<p><strong>Objective: </strong>Rising temperatures and extreme weather pose a significant public health threat. Workers in low- and middle-income countries are particularly vulnerable to heat stress, which can lead to psychological repercussions, including climate anxiety. This study investigated the psychological impacts of heat stress and coping strategies among workers in relation to climate anxiety.</p><p><strong>Method: </strong>A cross-sectional survey of 800 indoor and outdoor workers was conducted in 2024. Environmental heat stress was measured using a wet bulb globe temperature (WBGT) monitor, defining heat stress as exceeding task-specific threshold limits. Heat strain indicators (HSIs) such as core body temperature (CBT) and urine specific gravity (USG) were assessed alongside perceived heat stress and psychological impacts using a validated HOTHAPS questionnaire.</p><p><strong>Results: </strong>The WBGT exceeded recommended limits for 62% of workers (30.3 ± 5.0 °C). Among heat-exposed workers, 80% reported heat-related health symptoms, with a significant rise in HSIs, including CBT (AOR = 1.9; 95% CI: 1.4-2.7). Psychological symptoms were prevalent in 94% of exposed workers, with heightened risks of climate anxiety (AOR = 2.8), stress (AOR = 2.7), and mental fatigue (AOR = 3.7). Women and summer months showed greater vulnerability.</p><p><strong>Conclusion: </strong>Heat stress significantly affects psychological well-being among South Indian workers. Protective workplace policies are crucial to mitigating climate-induced psychological impacts.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"217-227"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-11-22DOI: 10.1080/19338244.2025.2591429
Kathlyn J Ronaldson, Win Wah, Cammie Tran, Alice J Owen, Robyn L Woods, Enayet K Chowdhury, John J McNeil, Karen Walker-Bone
Standard codes were assigned to each of up to 3 jobs reported by 12,498 healthy Australian participants of the ASPREE Longitudinal Study of Older Persons (ALSOP) aged ≥ 70 years. Ten job categories for men (n=5444; 92.5%) and 13 for women (n=6370; 90.8%) were generated by grouping like jobs. Inter-group distinctiveness was demonstrated by education, socio-economic status, and lifestyle factors for men and women for the occupational groups. Among men, the highest odds of age-adjusted hypertension were in general managers (1.40; 95% CI 1.08, 1.81) and tradespersons (1.29; 1.05, 1.58), with associations attenuated after controlling for lifestyle factors. Among women, the highest odds of hypertension were in nurses (1.40; 95% CI 1.05, 1.87) and clerks/secretaries (1.28; 1.01, 1.62) in multivariate analysis. This analysis indicates that those who are healthy at ≥ 70 years with a healthy lifestyle may suffer minimal detriment in regard to hypertension status from lifetime occupation.
在ASPREE老年人纵向研究(ALSOP)中,年龄≥70岁的12,498名健康的澳大利亚参与者报告了多达3种工作,每个工作都分配了标准代码。男性的10个工作类别(n=5444, 92.5%)和女性的13个工作类别(n=6370, 90.8%)是通过类似的工作分组产生的。在职业群体中,男性和女性的教育、社会经济地位和生活方式因素显示出群体间的独特性。在男性中,总经理(1.40;95% CI 1.08, 1.81)和商人(1.29;1.05,1.58)患年龄调整高血压的几率最高,在控制了生活方式因素后相关性减弱。多因素分析显示,女性中患高血压的几率最高的是护士(1.40;95% CI 1.05, 1.87)和文员/秘书(1.28;1.01,1.62)。这一分析表明,那些年龄≥70岁且生活方式健康的人,其终生职业对高血压的危害可能最小。
{"title":"Lifetime occupation assignment and hypertension analysis in a survivor cohort of older adults.","authors":"Kathlyn J Ronaldson, Win Wah, Cammie Tran, Alice J Owen, Robyn L Woods, Enayet K Chowdhury, John J McNeil, Karen Walker-Bone","doi":"10.1080/19338244.2025.2591429","DOIUrl":"10.1080/19338244.2025.2591429","url":null,"abstract":"<p><p>Standard codes were assigned to each of up to 3 jobs reported by 12,498 healthy Australian participants of the ASPREE Longitudinal Study of Older Persons (ALSOP) aged ≥ 70 years. Ten job categories for men (n=5444; 92.5%) and 13 for women (n=6370; 90.8%) were generated by grouping like jobs. Inter-group distinctiveness was demonstrated by education, socio-economic status, and lifestyle factors for men and women for the occupational groups. Among men, the highest odds of age-adjusted hypertension were in general managers (1.40; 95% CI 1.08, 1.81) and tradespersons (1.29; 1.05, 1.58), with associations attenuated after controlling for lifestyle factors. Among women, the highest odds of hypertension were in nurses (1.40; 95% CI 1.05, 1.87) and clerks/secretaries (1.28; 1.01, 1.62) in multivariate analysis. This analysis indicates that those who are healthy at ≥ 70 years with a healthy lifestyle may suffer minimal detriment in regard to hypertension status from lifetime occupation.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"291-302"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145582744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-08-11DOI: 10.1080/19338244.2025.2545779
Alexis Descatha, Jacqueline Moline, Marc Fadel, Grace Sembajwe
{"title":"Peer review: The good, the bad and the ugly.","authors":"Alexis Descatha, Jacqueline Moline, Marc Fadel, Grace Sembajwe","doi":"10.1080/19338244.2025.2545779","DOIUrl":"10.1080/19338244.2025.2545779","url":null,"abstract":"","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"201-202"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Traffic police play a crucial role in ensuring public safety and preventing accidents. This study assesses the occupational health of traffic police officers and brigade members in Gujarat. A cross-sectional study was conducted with 450 personnel, utilizing a semi-structured questionnaire and clinical examinations, including pulmonary function tests, blood tests, and lipid profiles. Results showed that male participants, particularly those with over 5 years of experience, had higher BMIs and reported elevated blood pressure, diabetes, and respiratory issues. Lung function declined with longer service, with significant reductions in FVC (p < 0.001) and FEV1 (p < 0.01). Female officers faced anemia, while male participants showed high cholesterol. Musculoskeletal discomfort, especially knee and back pain, was prevalent due to prolonged standing. These findings highlight the need for tailored health policies, regular checkups, protective gear, and ergonomic uniforms for Gujarat's traffic personnel.
{"title":"Occupational health status of traffic police personnel and traffic brigade members in Gujarat, India.","authors":"Priyanka Shah, Anish Sinha, Priya Dutta, Shreya Sharma, Shyam Pingle, Deepak Saxena","doi":"10.1080/19338244.2025.2478067","DOIUrl":"10.1080/19338244.2025.2478067","url":null,"abstract":"<p><p>Traffic police play a crucial role in ensuring public safety and preventing accidents. This study assesses the occupational health of traffic police officers and brigade members in Gujarat. A cross-sectional study was conducted with 450 personnel, utilizing a semi-structured questionnaire and clinical examinations, including pulmonary function tests, blood tests, and lipid profiles. Results showed that male participants, particularly those with over 5 years of experience, had higher BMIs and reported elevated blood pressure, diabetes, and respiratory issues. Lung function declined with longer service, with significant reductions in FVC (<i>p</i> < 0.001) and FEV1 (<i>p</i> < 0.01). Female officers faced anemia, while male participants showed high cholesterol. Musculoskeletal discomfort, especially knee and back pain, was prevalent due to prolonged standing. These findings highlight the need for tailored health policies, regular checkups, protective gear, and ergonomic uniforms for Gujarat's traffic personnel.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"23-37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-06-02DOI: 10.1080/19338244.2025.2510634
Gi Wook Ryu, Mona Choi
Police officers' mental health issues can impair their ability to perform duties safely and increase the required medical care for public health and police organizations. This study investigated police officers' mental health status, identified related factors, and analyzed their paths using the PRECEDE (Predisposing, Reinforcing, and Enabling Constructs in Educational Diagnosis and Evaluation) model. The results showed that 63.02% of the participants were in the potential stress group for mental health. Police officers' mental health was associated with resilience, social support, resource availability, health behaviors, job stress, and traumatic experiences. The path analysis showed that higher health behaviors and lower job stress were positively associated with better mental health. This study and model can guide the creation of health policies and intervention strategies aimed at enhancing the mental well-being of police officers.
{"title":"Factors affecting the mental health of police officers based on the PRECEDE model: A cross-sectional study.","authors":"Gi Wook Ryu, Mona Choi","doi":"10.1080/19338244.2025.2510634","DOIUrl":"10.1080/19338244.2025.2510634","url":null,"abstract":"<p><p>Police officers' mental health issues can impair their ability to perform duties safely and increase the required medical care for public health and police organizations. This study investigated police officers' mental health status, identified related factors, and analyzed their paths using the PRECEDE (Predisposing, Reinforcing, and Enabling Constructs in Educational Diagnosis and Evaluation) model. The results showed that 63.02% of the participants were in the potential stress group for mental health. Police officers' mental health was associated with resilience, social support, resource availability, health behaviors, job stress, and traumatic experiences. The path analysis showed that higher health behaviors and lower job stress were positively associated with better mental health. This study and model can guide the creation of health policies and intervention strategies aimed at enhancing the mental well-being of police officers.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"101-111"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01Epub Date: 2025-08-19DOI: 10.1080/19338244.2025.2545774
Mona Sharma, Navdeep Kaur
The sub-chronic testicular toxicity of nitrate in immature and mature albino rats and its amelioration with ascorbic acid and curcumin was studied. Rats were divided into five groups: control, nitrate, nitrate + ascorbic acid, nitrate + curcumin and nitrate + ascorbic acid + curcumin. Nitrate at 250 mg/L in drinking water and ascorbic acid and curcumin at 100 mg/kg body weight were provided to rats for 42 days. A significant increase in level of malondialdehyde and decreases in sperm parameters; level of testosterone, follicle-stimulating hormone and luteinizing hormone; antioxidant enzymes activity; and testis's histological alterations were observed in both age groups of rats due to nitrate, with immature rats being more affected. The testicular toxicity was more severe in immature rats compared to mature rats and effectively ameliorated by combination of ascorbic acid and curcumin, followed by curcumin and ascorbic acid individually in both age groups.
{"title":"Age-related nitrate-induced testicular toxicity in albino rats and its amelioration with ascorbic acid and curcumin.","authors":"Mona Sharma, Navdeep Kaur","doi":"10.1080/19338244.2025.2545774","DOIUrl":"10.1080/19338244.2025.2545774","url":null,"abstract":"<p><p>The sub-chronic testicular toxicity of nitrate in immature and mature albino rats and its amelioration with ascorbic acid and curcumin was studied. Rats were divided into five groups: control, nitrate, nitrate + ascorbic acid, nitrate + curcumin and nitrate + ascorbic acid + curcumin. Nitrate at 250 mg/L in drinking water and ascorbic acid and curcumin at 100 mg/kg body weight were provided to rats for 42 days. A significant increase in level of malondialdehyde and decreases in sperm parameters; level of testosterone, follicle-stimulating hormone and luteinizing hormone; antioxidant enzymes activity; and testis's histological alterations were observed in both age groups of rats due to nitrate, with immature rats being more affected. The testicular toxicity was more severe in immature rats compared to mature rats and effectively ameliorated by combination of ascorbic acid and curcumin, followed by curcumin and ascorbic acid individually in both age groups.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"203-215"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144884506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evidence suggests that hearing loss may increase the risk of burnout. This cross-sectional study examines the relationship between hearing loss and burnout among 292 industrial workers in the pharmaceutical, who were exposed to noise levels exceeding 85 db. Participants were categorized into three groups based on their hearing status: Normal Hearing, Acoustic Trauma, and Hearing Loss. Burnout was assessed using the Oldenburg Burnout Inventory (OLBI), while general health was measured using the SF-36 questionnaire. Regression analysis revealed that hearing status, age, and general health were significant predictors of burnout, with workers in the Hearing Loss group exhibiting the highest burnout scores. Paired t-tests showed that both the Hearing Loss and Acoustic Trauma groups had significantly higher burnout levels than matched normal hearing workers, even after adjusting for age, gender, and general health. These findings suggest hearing impairment contributes to burnout in noise-exposed industrial workers independent of confounding factors such as age or co morbidities.
{"title":"Exploring the relationship between burnout and hearing in pharmaceutical industry workers exposed to noisy environment.","authors":"Christos Karaiskos, Ioannis Vlastos, Georgios Rachiotis, Effie Simou, Georgios Dounias, Anastasia Kikemeni","doi":"10.1080/19338244.2025.2588594","DOIUrl":"10.1080/19338244.2025.2588594","url":null,"abstract":"<p><p>Evidence suggests that hearing loss may increase the risk of burnout. This cross-sectional study examines the relationship between hearing loss and burnout among 292 industrial workers in the pharmaceutical, who were exposed to noise levels exceeding 85 db. Participants were categorized into three groups based on their hearing status: Normal Hearing, Acoustic Trauma, and Hearing Loss. Burnout was assessed using the Oldenburg Burnout Inventory (OLBI), while general health was measured using the SF-36 questionnaire. Regression analysis revealed that hearing status, age, and general health were significant predictors of burnout, with workers in the Hearing Loss group exhibiting the highest burnout scores. Paired t-tests showed that both the Hearing Loss and Acoustic Trauma groups had significantly higher burnout levels than matched normal hearing workers, even after adjusting for age, gender, and general health. These findings suggest hearing impairment contributes to burnout in noise-exposed industrial workers independent of confounding factors such as age or co morbidities.</p>","PeriodicalId":93879,"journal":{"name":"Archives of environmental & occupational health","volume":" ","pages":"283-289"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}