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Serial electrocardiographic and echocardiographic assessments of cardiac amyloidosis presenting with myocardial ischemia 对出现心肌缺血的心脏淀粉样变性进行连续心电图和超声心动图评估
Pub Date : 2023-12-01 DOI: 10.5603/cj.97076
Takao Konishi, Akira Hamabe
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引用次数: 0
Nightmare as a trigger for stress cardiomyopathy 噩梦是应激性心肌病的诱因
Pub Date : 2023-12-01 DOI: 10.5603/cj.97167
Marc Arcens, Stephane Noble
A 67-year-old female was admitted to the emergency department with moderate dyspnea that escalated into oppressive chest pain after 4 hours. She had mild hypertension (153/107 mmHg) and sinus tachycardia (110 bpm). The electrocardiogram showed a left axis deviation without any signs of ischemia and a corrected QT interval of 471 ms (Fig. 1A). The biological markers showed a N-teminal-pro-B-type natriuretic peptide level of 1513 ng/L, peak troponins of 3502 ng/L, and peak creatine kinase of 306 U/L. The transthoracic echocardiogram (TTE) showed severe apical dysfunction with a left ventricular ejection fraction (LVEF) of 25% (Fig. 1B, Suppl. Video 1, Part 1 ). A left ventriculography (Fig. 1C, Suppl. Video 1, Part 2 ) and coronary angiography (Fig. 1D, E)
一名67岁女性因中度呼吸困难入院急诊,4小时后升级为压迫性胸痛。她有轻度高血压(153/107 mmHg)和窦性心动过速(110 bpm)。心电图显示左轴偏移,无缺血迹象,校正后QT间期为471 ms(图1A)。生物学指标显示n -末端前b型利钠肽水平为1513 ng/L,肌钙蛋白峰值为3502 ng/L,肌酸激酶峰值为306 U/L。经胸超声心动图(TTE)显示严重的心尖功能障碍,左心室射血分数(LVEF)为25%(图1B,补充资料)。视频1,第一部分)。左心室造影(图1C)。视频1,第2部分)和冠状动脉造影(图1D, E)
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引用次数: 0
Sky is the limit for Impella-assisted percutaneous coronary intervention: Four technologies, three vessels, two bifurcations and one chronic total occlusion Impella辅助经皮冠状动脉介入治疗的天空是无限的:四种技术、三条血管、两个分叉和一个慢性全闭塞
Pub Date : 2023-12-01 DOI: 10.5603/cj.96740
Aleksandra Gąsecka, Norbert Czyżak, Marcin Lampart, A. Pietrasik
A 73-year-old woman after percutaneous coronary intervention (PCI) of the left main (LM), left anterior descending (LAD) artery and diagonal branch with implantation of 5 drug-eluting stents (2020) was admitted due to heart failure exacerbation. Echocardiography showed left ventricular ejection fraction (LVEF) of 13%, severe secondary mitral regurgitation (MR) and moderate tricuspid regurgitation (TR). Coronary angiography demonstrated multivessel disease (SYNTAX score 47.5; Fig. 1A, B) with in-stent restenosis of the LM and LAD and chronic total occlusion of the circum - flex (Cx). Considering the high risk of mortality (EuroSCORE II 22.1
1例73岁女性经皮左主干(LM)、左前降支(LAD)及斜支介入治疗(PCI)并植入5个药物洗脱支架(2020)后因心力衰竭加重入院。超声心动图显示左室射血分数(LVEF) 13%,严重继发性二尖瓣反流(MR)和中度三尖瓣反流(TR)。冠状动脉造影显示多支血管病变(SYNTAX评分47.5;图1A, B)与支架内LM和LAD再狭窄和环屈曲慢性完全闭塞(Cx)。考虑到高死亡率(EuroSCORE II 22.1)
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引用次数: 0
Stiff wire scratching to fenestration, de-escalation, and re-entry technique (SSDR): A novel wire-based antegrade dissection/re-entry technique for coronary chronic total occlusion recanalization. 硬钢丝刮除开窗、减压和再通技术(SSDR):一种用于冠状动脉慢性完全闭塞再通的新型钢丝顺行剥离/再通技术。
Pub Date : 2023-01-01 Epub Date: 2023-09-29 DOI: 10.5603/cj.92864
Mihajlo Kovačić
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引用次数: 0
The use of cardiac markers in the prediction of COVID-19. 心脏标志物在新冠肺炎预测中的应用。
Pub Date : 2023-01-01 Epub Date: 2023-09-29 DOI: 10.5603/cj.96345
Mohamad Gholamhosain Moghadam, Małgorzata Cielicka, Piotr Łojko
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引用次数: 0
AngioScore: An artificial intelligence tool to assess coronary artery lesions. AngioScore:一种评估冠状动脉病变的人工智能工具。
Pub Date : 2023-01-01 Epub Date: 2023-10-12 DOI: 10.5603/cj.95508
Ewelina Blazejowska, Jakub Michal Zimodro, Tomasz Figatowski, Adam Brzeski, Tomasz Dziubich, Jaroslaw Parzuchowski, Aleksandra Gasecka, Radoslaw Targonski
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引用次数: 0
Beyond ChatGPT: What does GPT-4 add to healthcare? The dawn of a new era. 超越ChatGPT:GPT-4为医疗保健增加了什么?一个新时代的黎明。
Pub Date : 2023-01-01 Epub Date: 2023-10-13 DOI: 10.5603/cj.97515
Simona Wójcik, Anna Rulkiewicz, Piotr Pruszczyk, Wojciech Lisik, Marcin Poboży, Justyna Domienik-Karłowicz

Over the past few years, artificial intelligence (AI) has significantly improved healthcare. Once the stuff of science fiction, AI is now widely used, even in our daily lives - often without us thinking about it. All healthcare professionals - especially executives and medical doctors - need to understand the capabilities of advanced AI tools and other breakthrough innovations. This understanding will allow them to recognize opportunities and threats emerging technologies can bring to their organizations. We hope to contribute to a meaningful public discussion about the role of this new type of AI and how our approach to healthcare and medicine can best evolve with the rapid development of this technology. Since medicine learns by example, only a few possible uses of AI in medicine are provided, which merely outline the system's capabilities. Among the examples, it is worth highlighting the roles of AI in medical notes, education, preventive programs, consultation, triage and intervention. It is believed by the authors that large language models such as chat generative pre-trained transformer (ChatGPT) are reaching a level of maturity that will soon impact clinical medicine as a whole and improve the delivery of individualized, compassionate, and scalable healthcare. It is unlikely that AI will replace physicians in the near future. The human aspects of care, including empathy, compassion, critical thinking, and complex decision-making, are invaluable in providing holistic patient care beyond diagnosis and treatment decisions. The GPT-4 has many limitations and cannot replace direct contact between an experienced physician and a patient for even the most seemingly simple consultations, not to mention the ethical and legal aspects of responsibility for diagnosis.

在过去的几年里,人工智能显著改善了医疗保健。人工智能曾经是科幻小说中的东西,现在被广泛使用,甚至在我们的日常生活中——通常我们都没有想过。所有医疗保健专业人员——尤其是高管和医生——都需要了解先进人工智能工具和其他突破性创新的能力。这种理解将使他们能够认识到新兴技术可能给其组织带来的机遇和威胁。我们希望为一场有意义的公众讨论做出贡献,讨论这种新型人工智能的作用,以及我们的医疗保健和医学方法如何随着这项技术的快速发展而最好地发展。由于医学是通过例子学习的,因此只提供了人工智能在医学中的几种可能用途,这些用途只是概述了系统的能力。在这些例子中,值得强调的是人工智能在医学笔记、教育、预防计划、咨询、分诊和干预中的作用。作者认为,聊天生成预训练转换器(ChatGPT)等大型语言模型正在达到成熟水平,这将很快影响整个临床医学,并改善个性化、富有同情心和可扩展的医疗保健的提供。人工智能不太可能在不久的将来取代医生。护理的人性方面,包括同理心、同情心、批判性思维和复杂决策,在提供诊断和治疗决策之外的整体患者护理方面是非常宝贵的。GPT-4有很多局限性,即使是看似最简单的咨询,也无法取代经验丰富的医生和患者之间的直接接触,更不用说诊断责任的伦理和法律方面了。
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引用次数: 0
Right superior pulmonary vein parameter determined by three-dimensional transesophageal echocardiography is an independent predictor of the outcome after cryoballoon isolation of the pulmonary veins. 三维经食管超声心动图测定的右上肺静脉参数是冷冻球囊分离肺静脉后结果的独立预测指标。
Pub Date : 2023-01-01 Epub Date: 2023-10-19 DOI: 10.5603/cj.95381
Laszlo Tibor Nagy, Timea Bianka Papp, Reka Urbancsek, Csaba Jenei, Zoltan Csanadi

Background: A direct comparison of three-dimensional transesophageal echocardiography (3DTEE) and cardiac computed tomography imaging has demonstrated good inter-technique agreement for the following pulmonary vein (PV) parameters: the ostium area of the right superior PV (RSPV) and its major (a) and minor axis (b) diameters, the left lateral ridge and the minor axis (b) diameter of the left superior PV. Herein, under investigation, was the predictive value of these parameters for arrhythmia recurrence (AR) after PV isolation with the 28 mm second generation cryoballoon (CBG2).

Methods: One hundred eleven patients (67 men, mean age 58.06 ± 10.58 years) undergoing 3DTEE before PV isolation with the CBG2 for paroxysmal atrial fibrillation were followed. "Point by point" redo intervention was offered in case of AR and reconnected PVs were defined.

Results: During a mean follow-up of 617 ± 258.86 days, 65 (58.9%) patients remained free of AR. Longer RSPV b was found to be the only significant predictor for AR (hazard ratio [HR] 1.059; 95% confidence interval [CI] 1.000-1.121; p = 0.048). RSPV b ≥ 28 mm resulted in a threefold (HR 3.010; 95% CI 1.270-7.134, p = 0.012) increase in the risk of AR. The association of RSPV b with AR was independent of the biophysical parameters of cryoapplications. In 25 "redo" patients, reconnections were found 1.75 times more likely in the RSPV than in the other 3 PVs altogether.

Conclusions: Right superior PV b measured with 3DTEE might be a significant predictor of AR after PV isolation with the CBG2. In case of RSPV b exceeding 28 mm, alternative PV isolation techniques or use of a larger balloon might be considered.

背景:三维经食管超声心动图(3DTEE)和心脏计算机断层扫描成像的直接比较表明,以下肺静脉(PV)参数在技术间具有良好的一致性:右上肺静脉(RSPV)的口面积及其长轴(A)和短轴(b)直径,左侧脊和左上PV的短轴(b)直径。在此,我们正在研究这些参数对28mm第二代冷冻气球(CBG2)PV隔离后心律失常复发(AR)的预测价值。方法:对111例(67名男性,平均年龄58.06±10.58岁)在CBG2 PV隔离前接受3DTEE的阵发性心房颤动患者进行随访。在AR的情况下提供了“逐点”重做干预,并定义了重新连接的PV。结果:在617±258.86天的平均随访中,65名(58.9%)患者没有AR。发现较长的RSPV b是AR的唯一显著预测因素(危险比[HR]1.059;95%置信区间[CI]1.00-1.121;p=0.048)。RSPV b≥28 mm导致AR风险增加三倍(HR3.010;95%CI1.270-7.134,p=0.012)。RSPV b与AR的相关性与冷冻应用的生物物理参数无关。在25名“重做”患者中,发现RSPV中重新连接的发生率是其他3个PV的1.75倍。结论:3DTEE测量右上肺静脉b可能是CBG2分离肺静脉后AR的重要预测指标。如果RSPV b超过28 mm,可能会考虑采用替代PV隔离技术或使用更大的气球。
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引用次数: 0
Novel planned two-stent technique for bifurcation lesions: Inverted compression T-stenting. 针对分叉病变的新型计划双支架技术:倒置压缩t型支架置入。
Pub Date : 2023-01-01 Epub Date: 2023-11-21 DOI: 10.5603/cj.97345
Fumiaki Nakao
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引用次数: 0
STRUGGLE FOR. Italian-Polish-Spanish-Uzbek-Vietnamese Expert Forum Position Paper 2023 for better control of classical modifiable risk factors in clinical practice. 争取。意大利-波兰-西班牙-乌兹别克斯坦-越南专家论坛立场文件2023在临床实践中更好地控制经典可改变的风险因素。
Pub Date : 2023-01-01 Epub Date: 2023-11-21 DOI: 10.5603/cj.96912
Krzysztof J Filipiak, Vivencio Barrios, Claudio Ferri, Khurshid Fozilov, Santiago Jesus Freire Castro, Agnieszka Kuzior, Francisco Javier Martinez-Martin, Guzal Mullabaeva, Lan Hieu Nguyen, Ulugbek Nizamov, Anna Tomaszuk-Kazberuk, Raisa Trigulova, Aleksandra Gąsecka

The progress in pharmacotherapy that has been made in recent years, including the introduction of very effective and safe lipid-lowering and antihypertensive drugs, has not yet translated into the expected universal control of blood pressure, lipid disorders and diabetes. In the STRUGGLE FOR Italian- -Polish-Spanish-Uzbek-Vietnamese Expert Forum Position Paper 2023, experts from five countries recounted several points about the paradigms of cardiological and cardiometabolic care for better control of classical modifiable risk factors in the year 2023. It is believed herein, that the need to intensify treatment, actively search for patients with cardiovascular risk factors, especially with arterial hypertension, hypercholesterolemia and diabetes, should go hand in hand with the implementation of the latest therapy, based on single pill combinations including proven, effective antihypertensive, lipid-lowering and antidiabetic molecules, many of which are listed in the present document. There is a need to use both new technological concepts, completely new drugs, as well as novel treatment concepts such as metabolic treatment in coronary artery disease, try to intensify the fight against smoking in every way, including the available range of drugs and procedures reducing the harm. This approach will provide substantially better control of the underlying cardiovascular risk factors in countries as varied as Italy, Poland, Spain, Uzbekistan and Vietnam.

近年来在药物治疗方面取得的进展,包括引入非常有效和安全的降脂和降压药物,尚未转化为预期的血压、脂质紊乱和糖尿病的普遍控制。在《2023年意大利-波兰-西班牙-乌兹别克斯坦-越南专家论坛立场文件》中,来自五个国家的专家讲述了关于2023年更好地控制经典可改变风险因素的心脏病和心血管代谢护理范例的几点。本文认为,在加强治疗、积极寻找有心血管危险因素的患者,特别是动脉高血压、高胆固醇血症和糖尿病患者的同时,应同时实施最新的单药联合治疗,包括已证实有效的降压、降脂和降糖分子,其中许多在本文件中列出。有必要使用新的技术概念,全新的药物,以及新的治疗概念,如冠状动脉疾病的代谢治疗,试图从各个方面加强与吸烟的斗争,包括现有的药物范围和减少危害的程序。在意大利、波兰、西班牙、乌兹别克斯坦和越南等国家,这种方法将大大更好地控制潜在的心血管危险因素。
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