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Variant ELMO1 rs1345365 is associated with pseudoperniosis in patients with COVID-19. 变异体 ELMO1 rs1345365 与 COVID-19 患者的假疝有关。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.22000470
Carlos E Cabrera-Pivaral, Sergio A Ramírez-García, Judan Orozco-Sánchez, Víctor Castañeda-Salazar, José Domínguez-Rodas
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引用次数: 0
Colorectal endometriosis. A proposal of complementary classification and surgical management in stages. 结肠直肠子宫内膜异位症。关于补充分类和分阶段手术治疗的建议。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.23000251
Armando Cepeda-Silva, Harald Krentel, Oliver P Cruz-Orozco, Jorge L Vela-Cantorán, Edgar González-Macedo, Alejandro Rendón-Molina, José R Silvestri-Tomassoni

Objective: To organize the experience and international knowledge in the surgical management and staging of colorectal endometriosis, with a management proposal in stages.

Method: An extensive non-systematic review of the literature was carried to organize the disease in stages (limited, intermediate and advanced) according to a scoring system, which considers the characteristics of the endometrioma, the personal history and surgical findings. We tested the proposed staging in a retrospective group of patients.

Results: From January 2017 to April 2023, we collected 19 patients with a confirmed diagnosis of colorectal endometriosis, treated laparoscopically, by the same group of surgeons, in whom we found a strong correlation between the stage of the disease and the presence of complications that required reinterventions.

Conclusions: We suggest a sequence of colorectal surgical management in stages according to the staging of the disease and we hope that this work will be followed by joint efforts to test it prospectively in order to compare results between hospital centers and make planned decisions.

目的整理结直肠子宫内膜异位症手术治疗和分期方面的经验和国际知识,并提出分期治疗建议:方法:我们对文献进行了广泛的非系统性综述,根据评分系统对疾病进行分期(局限期、中期和晚期),评分系统考虑了子宫内膜异位症的特征、个人病史和手术结果。我们在一组回顾性患者中检验了所提出的分期方法:从2017年1月到2023年4月,我们收集了19名确诊为结肠直肠子宫内膜异位症的患者,由同一组外科医生进行腹腔镜治疗,我们发现疾病的分期与是否出现需要再次干预的并发症之间存在很强的相关性:我们建议根据疾病的分期对结肠直肠手术进行分期治疗,并希望在这项工作之后,各方能共同努力对其进行前瞻性测试,以比较不同医院中心的结果,并做出有计划的决策。
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引用次数: 0
Effects of different surgical treatments on pain, disability, anxiety and quality of life in lumbar disc herniation. 不同手术疗法对腰椎间盘突出症患者疼痛、残疾、焦虑和生活质量的影响。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.23000415
Aydin S Apaydin, Bülent Bozyiğit, Zuhal Koç-Apaydin, Musa Güneş, Metehan Yana

Objective: This study aims to compare the effects of microscopic microdiscectomy and microendoscopic discectomy on pain, disability, fear of falling, kinesiophobia, anxiety, quality of life in patients with lumbar disc herniation (LDH).

Methods: A total of 90 patients who underwent microscopic microdiscectomy (n = 40) and microendoscopic discectomy (n = 50) for LDH were included in this study. The patients' pain, disability, fear of falling, kinesiophobia, anxiety, and quality of life were evaluated before the surgery, in the early postoperative period and three months after.

Results: In patients who underwent microendoscopic discectomy, the results of pain, disability, fear of falling, kinesiophobia and anxiety were statistically decreased compared with the microscopic microdiscectomy in the early postoperative period and three months later (p < 0.05). Also, a statistically higher increase was observed in the general health perception of patients who underwent microendoscopic discectomy three months after the operation (p < 0.01).

Conclusion: Microendoscopic microdiscectomy, remains the most effective and widely applied method with advantages on pain, quality of life, and improved physical functions.

研究目的本研究旨在比较显微镜下椎间盘切除术和显微内镜下椎间盘切除术对腰椎间盘突出症(LDH)患者疼痛、残疾、跌倒恐惧、运动恐惧、焦虑和生活质量的影响:本研究共纳入了 90 名接受显微镜下椎间盘切除术(40 人)和显微内镜下椎间盘切除术(50 人)的腰椎间盘突出症患者。对患者术前、术后早期和术后三个月的疼痛、残疾、跌倒恐惧、运动恐惧、焦虑和生活质量进行了评估:结果:与显微镜下椎间盘切除术相比,接受显微内镜下椎间盘切除术的患者在术后早期和三个月后的疼痛、残疾、跌倒恐惧、运动恐惧和焦虑程度均有统计学意义的下降(P < 0.05)。此外,接受显微内窥镜椎间盘切除术的患者在术后三个月后的总体健康感知也有显著提高(P < 0.01):结论:显微内窥镜椎间盘切除术仍是最有效、应用最广泛的方法,在减轻疼痛、提高生活质量和改善身体功能方面具有优势。
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引用次数: 0
Table of life for beneficiaries of the Institute of Security and Social Services of State Workers (ISSSTE), Mexico 2021. 2021 年墨西哥国家劳动者保障和社会服务局(ISSSTE)受益人生活表。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.23000321
Judith E García-de-Alba-Verduzco, Javier E García-de-Alba-Verduzco, Ramiro López-Elizalde, Javier E García-de-Alba-García

Objective: Determine the life expectancy in the covered population of the Institute of Security and Social Services of State Workers in México for 2021.

Method: We used the abrogated method from Reed-Merrel, for calculate the life expectancy in age groups.

Results: By 2021, life expectancy general was 79.51 years; 81.40 years and 78.91 years for woman and men, respectively.

Conclusions: The calculated life expectancy not show a reduction in the population of federal and State employees in Mexico.

目标:确定 2021 年墨西哥国家劳动者保障和社会服务局受保人口的预期寿命:确定 2021 年墨西哥国家劳动者保障和社会服务局覆盖人口的预期寿命:方法:我们使用里德-梅雷尔(Reed-Merrel)的废除法计算各年龄组的预期寿命:到 2021 年,女性和男性的一般预期寿命分别为 79.51 岁、81.40 岁和 78.91 岁:计算得出的预期寿命并未显示墨西哥联邦和各州雇员人口的减少。
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引用次数: 0
Transcendence of scientific research: dissemination, diffusion, and impact factor. 科学研究的超越性:传播、扩散和影响因子。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.230005791
Alejandro Navas-Pérez, Virgilio Lima-Gómez, Sergio Sobrino-Cossío
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引用次数: 0
Can platelet activation markers predict preeclampsia and/or its severity? 血小板活化标记物能否预测子痫前期和/或其严重程度?
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.23000226
Tuğçe Arslanoğlu, Kübra Kurt-Bilirer, Nihal Çallıoğlu, Selvi Aydın-Şenel, Işıl Turan-Bakırcı, İklil N Koç-Erol, Emre Kar, Zeliha Bayram, Ibrahim Polat

Objective: This study aimed to evaluate the value of platelet activation markers in predicting preeclampsia and its severity. Preeclampsia is a serious pregnancy complication that affects 3-5% of pregnancies and can lead to significant morbidity and mortality for both the mother and the fetus.

Methods: The study included 99 patients diagnosed with preeclampsia and 60 healthy pregnant women as a control group. Platelet activation markers such as mean platelet volume (MPV), platelet distribution width (PDW), platelet count, and plateletcrit were evaluated along with other clinical parameters.

Results: The results of the study showed that platelet activation markers, particularly PDW and MPV, are valuable in the diagnosis and follow-up of preeclampsia. However, they are not sufficient to predict the severity of the disease.

Conclusion: The study suggests that platelet activation markers could aid in predicting, diagnosing, and managing preeclampsia. However, further research is needed to determine the role of these markers in predicting the severity of the disease. The findings of this study could contribute to the development of more effective strategies for the prevention and management of preeclampsia, which could ultimately improve maternal and fetal outcomes.

研究目的本研究旨在评估血小板活化标记物在预测子痫前期及其严重程度方面的价值。子痫前期是一种严重的妊娠并发症,影响3%-5%的妊娠,可导致母亲和胎儿严重发病和死亡:研究包括 99 名确诊为子痫前期的患者和 60 名健康孕妇作为对照组。在评估其他临床参数的同时,还评估了血小板活化指标,如血小板平均体积(MPV)、血小板分布宽度(PDW)、血小板计数和血小板脆性(plateletcrit):研究结果表明,血小板活化标志物,尤其是血小板分布宽度(PDW)和血小板平均容积(MPV),对子痫前期的诊断和随访很有价值。结果:研究结果表明,血小板活化标志物,尤其是 PDW 和 MPV,对诊断和随访子痫前期很有价值,但不足以预测疾病的严重程度:研究表明,血小板活化标志物有助于预测、诊断和管理子痫前期。然而,要确定这些标记物在预测疾病严重程度方面的作用,还需要进一步的研究。这项研究的结果有助于制定更有效的子痫前期预防和管理策略,最终改善孕产妇和胎儿的预后。
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引用次数: 0
Efficacy of diltiazem 2% rectal gel in the treatment of chronic anal fissure: a retrospective observational study. 2% 地尔硫卓直肠凝胶治疗慢性肛裂的疗效:一项回顾性观察研究。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.22000626
Gabriel Martínez-Orea, Francisco J Rodríguez-Lucena, Celia García-González, Nieves Cano-Cuenca, Ana Candela-Fajardo, Rodrigo Bonilla-Peñarrubia

Objective: The aim of this study is to describe the effectiveness and safety of a magistral formulation of diltiazem 2% rectal gel as a treatment for chronic anal fissure.

Material and methods: A retrospective observational study of all patients that began treatment with diltiazem 2% gel during 2019. The primary endpoint of the study was anal fissure healing. We also looked for differences in effectiveness between those initiating treatment and those who had been previously treated, long-term effectiveness through a 2-year follow-up and frequency of adverse effects.

Results: Of the 166 patients included in the study, anal fissure healed in 72.9%. We detected adverse effects in 12 patients, the most common was local irritation. After 2 years of follow-up, 88% of patients did not relapse.

Conclusion: In this study, use of topical diltiazem 2% has been shown to be effective and safe in the treatment of anal fissure and should be considered as the first line of therapy.

研究目的本研究旨在描述2%地尔硫卓直肠凝胶口服制剂治疗慢性肛裂的有效性和安全性:对2019年期间开始使用2%地尔硫卓凝胶治疗的所有患者进行回顾性观察研究。研究的主要终点是肛裂愈合。我们还观察了开始治疗者与之前接受过治疗者的疗效差异、2年随访的长期疗效以及不良反应发生频率:结果:在参与研究的 166 名患者中,72.9% 的肛裂患者痊愈。我们发现12名患者出现了不良反应,最常见的是局部刺激。经过两年的随访,88%的患者没有复发:这项研究表明,局部使用 2% 地尔硫卓治疗肛裂既有效又安全,应将其作为一线疗法。
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引用次数: 0
Presentation of Wernicke encephalopathy in patient secondary to one anastomosis gastric bypass. Case report and literature review. 单吻合胃旁路术后继发 Wernicke 脑病。病例报告和文献综述。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.21000706
Luis F Zorrilla-Núñez, Luis Tamez-Pedroza, Patricio Durán-Moreno, Gerardo E Muñoz-Maldonado

Wernicke encephalopathy, which is caused by a thiamine deficiency, occurs in 0.8-2% of the population. Only 16% present the typical triad of this disease: nystagmus, confusion and ataxia. We present the case of a postoperative patient with a one anastomosis gastric bypass with reoperation undergoing a Roux-en-Y gastric bypass that begins with confusion and nystagmus on her third postoperative day. The diagnosis of Wernicke encephalopathy is made by imaging, and vitamin B1 is administered with total improvement of nystagmus and altered state of consciousness (lethargy, bradypsychia, bradylalia).

韦尼克脑病是由硫胺素缺乏症引起的,发病率为 0.8%-2%。只有 16% 的患者会出现这种疾病的典型三联征:眼球震颤、意识模糊和共济失调。我们介绍了一例接受 Roux-en-Y 胃旁路术的单吻合胃旁路术后患者,她在术后第三天开始出现意识模糊和眼球震颤。通过影像学检查确诊为 Wernicke 脑病,服用维生素 B1 后,眼球震颤和意识状态改变(嗜睡、精神错乱、肢体瘫痪)得到完全改善。
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引用次数: 0
Proximal jejunal GIST associated with massive gastrointestinal bleeding. Case report. 空肠近端 GIST 伴有大量消化道出血。病例报告。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.22000464
José J Vargas-Montes, Miguel E Yado-López, Pamela L Huerta-Martínez, Barbara I Rojo-Rodríguez, Antonio Tirado-Motel

Introduction: Gastrointestinal stromal tumors (GIST) are rare, reported incidence is between 10 to 15 cases per million of habitants. They are usually located in the stomach (56%), small intestine (32%), colon-rectum (6%), and esophagus (<1%). Its symptoms include nausea, vomiting and abdominal fullness; 30% are asymptomatic. Incidental finding during abdominal surgery or imaging studies is common. Resection with negative margins is the standard treatment.

Case report: A 69-year-old female patient who debuted with massive digestive tract bleeding, requiring surgical treatment. A tumor was detected at jejunum compatible with a GIST.

导言:胃肠道间质瘤(GIST)十分罕见,据报道发病率为每百万人中有10至15例。它们通常位于胃(56%)、小肠(32%)、结肠直肠(6%)和食道(病例报告:一名 69 岁的女性患者因消化道大量出血而就诊,需要手术治疗。在空肠处发现了一个肿瘤,与 GIST 相吻合。
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引用次数: 0
Treatment effectiveness according to frequencies in patients with sudden sensorineural hearing loss. 根据频率对突发性感音神经性听力损失患者进行治疗的有效性。
Pub Date : 2024-01-01 DOI: 10.24875/CIRU.24000204
Ahmet Celik, Ferit Akil

Objective: The objective of the study is to evaluate combined hyperbaric oxygen therapy (HBOT) and steroids on hearing in sudden sensorineural hearing loss (SSNHL) patients.

Method: A total of 50 patients with sudden hearing loss that started within 1 week and who received a combination of intravenous steroid therapy and HBOT in their medical treatment were assigned to the otolaryngology department for 1 week, followed by intravenous steroid therapy at 1 mg/kg/day and then reduced doses for 1 week. They were treated once in a hyperbaric chamber where they breathed 100% oxygen at 2.5 atm pressure for 60 min, for a total of 20 sessions.

Results: Hearing loss was observed in 54% of participants in the right ear. Significant improvements were observed in hearing thresholds across all tested frequencies after treatment with a specific intervention (p < 0.001 for each comparison). Combined steroid and HBOT significantly improved hearing across low and high frequencies (p < 0.001). Improvement in hearing at low frequencies was significantly greater than at high frequencies (p < 0.01). Post hoc analysis showed greater hearing improvement at lower frequencies compared to higher ones.

Conclusions: This study demonstrated that combined steroid and HBOT significantly improves hearing thresholds in patients with idiopathic SSNHL, especially at lower frequencies.

研究目的本研究旨在评估高压氧疗法(HBOT)和类固醇联合疗法对突发性感音神经性听力损失(SSNHL)患者听力的影响:方法:将 50 名在 1 周内开始出现突发性听力损失、在医疗过程中接受过静脉类固醇疗法和高压氧疗法联合治疗的患者分配到耳鼻喉科治疗 1 周,然后以 1 毫克/千克/天的剂量进行静脉类固醇治疗,再减量治疗 1 周。他们在高压氧舱内接受一次治疗,在2.5个大气压下呼吸100%氧气60分钟,共20次:结果:54%的参与者右耳出现听力损失。在接受特定干预治疗后,所有测试频率的听阈均有显著改善(每次比较的 P < 0.001)。类固醇和 HBOT 联合治疗可显著改善低频和高频的听力(p < 0.001)。低频听力的改善程度明显高于高频(p < 0.01)。事后分析表明,低频与高频相比,听力改善幅度更大:本研究表明,联合使用类固醇和 HBOT 可明显改善特发性 SSNHL 患者的听阈,尤其是低频听阈。
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引用次数: 0
期刊
Cirugia y cirujanos
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