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VRR-CPD: adapting free and open-access distance simulation for the continuing interprofessional education of community emergency department providers on caring for children with acute emergencies. VRR-CPD:将免费和开放获取的远程模拟应用于社区急诊科提供者关于照顾急症儿童的持续跨专业教育。
IF 2 Pub Date : 2026-02-04 DOI: 10.1007/s43678-025-01083-1
James Leung, Sabrina Lue Tam, Allim Nagji, Sarah Foohey, Jabeen Fayyaz

Objectives: Most Canadian children (~ 80%) receive emergency care in general Emergency Departments (general EDs), which often lack pediatric readiness compared to Pediatric Emergency Departments (pediatric ED) and lead to poorer outcomes. Travelling on-site outreach simulation for Continuing Professional Development (CPD) can improve readiness but is resource-intensive. This study evaluates the acceptability and logistics of the Virtual Resus Room© (VRR), a free, online simulation platform for delivering pediatric outreach education remotely.

Methods: A multi-centre quasi-experimental simulation study was conducted with independently practicing physicians and nurses from 12 general EDs networked with two pediatric ED. Participants worked in teams, completing a 3.5-h VRR-CPD session with debriefing. Acceptability was assessed according to the Universal Theory of Acceptance and Use of Technology (UTAUT) framework using Simulation Effectiveness Tool Modified, Systems Usability Scale, Net Promoter Score (NPS) and open-text survey responses. Distance, time, and cost were compared to travelling outreach models.

Results: Thirty-seven participants from 9/12 general EDs completed 10 sessions over 10.5 h-more sessions than would be feasible traditionally. Participants and facilitators reported high educational value, strong ease-of-use, and above-average NPS (60 and 71). Feedback praised accessibility and high-quality debriefs, but noted challenges with internet reliability, simultaneous conversations, and decreased allied health engagement from platform constraints. VRR-CPD simulation had significant distance, cost ($668.50 vs $929.06/session) and time savings (210 vs 423 min).

Conclusions: VRR-based virtual simulation is a feasible, accessible, and resource-efficient continuing professional development tool. VRR-CPD can aid pediatric readiness efforts with more broader and equitable reach than traditional models, especially when paired with hybrid education approaches.

目的:大多数加拿大儿童(约80%)在普通急诊科(general emergency department, general ED)接受急诊护理,与儿科急诊科(pediatric emergency department,儿科急诊科)相比,普通急诊科往往缺乏儿科准备,导致较差的结果。持续专业发展(CPD)的旅行现场拓展模拟可以提高准备程度,但需要大量资源。本研究评估了虚拟救援室©(VRR)的可接受性和后勤保障,VRR是一个免费的在线模拟平台,用于远程提供儿科外展教育。方法:对来自12个普通急诊科和2个儿科急诊科的独立执业医师和护士进行了一项多中心准实验模拟研究。参与者以团队形式工作,完成3.5小时的VRR-CPD会议并进行汇报。可接受性根据技术接受和使用的通用理论(UTAUT)框架进行评估,使用模拟有效性工具修改、系统可用性量表、净推荐值(NPS)和开放文本调查反馈。将距离、时间和成本与旅行外展模式进行比较。结果:来自9/12个普通急诊科的37名患者在10.5 h内完成了10次治疗,比传统方法多出了10次治疗。参与者和引导者报告了较高的教育价值,易用性强,NPS高于平均水平(60和71)。反馈赞扬了可访问性和高质量的汇报,但指出了互联网可靠性、同步对话以及平台限制导致的联合卫生参与减少等挑战。VRR-CPD模拟具有显著的距离、成本(668.50美元对929.06美元/次)和时间节省(210分钟对423分钟)。结论:基于vrr的虚拟仿真是一种可行、可及、资源高效的持续专业发展工具。VRR-CPD可以比传统模式更广泛、更公平地帮助儿科准备工作,特别是与混合教育方法相结合时。
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引用次数: 0
Reducing antibiotic overuse in immunocompetent children with febrile neutropenia in a pediatric emergency department: a quality improvement initiative. 减少儿童急诊科发热性中性粒细胞减少症免疫能力儿童抗生素过度使用:一项质量改进倡议。
IF 2 Pub Date : 2026-02-03 DOI: 10.1007/s43678-026-01091-9
Katherine Girgulis, Jennifer Thull-Freedman, Nicola Wright

Introduction: Management of febrile neutropenia in previously healthy, presumed immunocompetent children varies. Unnecessary treatment impacts the patients, families, and the healthcare system. With guidance from a Canadian Paediatric Society Practice Point, most well-appearing children with a first episode of febrile neutropenia can be managed with reduced exposure to antibiotics and close outpatient follow-up. The aim of this initiative was to safely reduce antibiotic use in this low-risk population presenting to the emergency department (ED).

Methods: A multidisciplinary team designed a quality improvement (QI) initiative. From July 2022 to July 2024, treatment with antibiotics was classified as indicated or non-indicated according to guidance from the Practice Point. Interventions involved guideline dissemination, provider education, and point-of-care tools to facilitate clinical decision-making and follow-up. Outcome measures included the proportion of children receiving antibiotics, hospital admission, and appropriate laboratory follow-up. Re-presentation to ED and missed serious bacterial infections were monitored as balancing measures. Analysis of the primary outcome was by statistical process control.

Results: Three hundred and ninety-eight (398) children with febrile neutropenia were included. The proportion of non-indicated antibiotics was 6.7% at baseline. Statistical process control analysis of the G-chart demonstrated special cause variation with 97 consecutive cases occurring without error (non-indicated antibiotics). Following the occurrence of special cause variation until the end of the study, only 1.6% of children received non-indicated antibiotics. There was no increase in re-presentations to ED (9% vs 8%; p = 0.65) nor missed serious bacterial infections (0% vs 0%).

Conclusions: Quality improvement methodology can facilitate the timely adoption of best practices to align local clinical care with new national guidelines. Implementation of the national guideline allowed low-risk children with febrile neutropenia to avoid overtreatment.

导论:在先前健康,假定免疫功能正常的儿童中,发热性中性粒细胞减少症的处理方法各不相同。不必要的治疗会影响患者、家庭和医疗保健系统。根据加拿大儿科学会实践要点的指导,大多数首发发热性中性粒细胞减少症患儿表现良好,可通过减少抗生素接触和密切门诊随访进行治疗。这一举措的目的是安全地减少抗生素的使用在这低风险人群呈现到急诊科(ED)。方法:一个多学科团队设计了一个质量改进(QI)计划。2022年7月至2024年7月,根据《实践要点》的指导,将抗生素治疗分为指征和非指征。干预措施包括指南传播、提供者教育和护理点工具,以促进临床决策和随访。结果测量包括接受抗生素治疗的儿童比例、住院率和适当的实验室随访。监测再次出现ED和漏诊严重细菌感染作为平衡措施。主要结局分析采用统计过程控制。结果:共纳入398例发热性中性粒细胞减少症患儿。基线时非指征抗生素的比例为6.7%。g图的统计过程控制分析显示了特殊原因的变化,连续97例无差错(非指征抗生素)。在特殊原因变异发生后,直到研究结束,只有1.6%的儿童接受了非指征抗生素治疗。再次出现ED的病例没有增加(9% vs 8%; p = 0.65),也没有遗漏严重细菌感染(0% vs 0%)。结论:质量改进方法可以促进及时采用最佳实践,使当地临床护理与新的国家指南保持一致。国家指南的实施使患有发热性中性粒细胞减少症的低风险儿童避免了过度治疗。
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引用次数: 0
Evaluating the quality of Canadian pediatric sepsis clinical practice guidelines. 评价加拿大儿童败血症临床实践指南的质量。
IF 2 Pub Date : 2026-02-03 DOI: 10.1007/s43678-025-01084-0
Vikram Sabhaney, Meghan Gilley, Gabrielle Freire, Simon Berthelot, Yasaman Shayan, Tania Principi, Karen Gripp, Katie Gardner, Deborah Schonfeld, Gina Neto, Archna Shah, Graham C Thompson, Elliot Long, Garth Meckler

Objectives: Sepsis is a common and clinically challenging life-threatening condition affecting children. Well-designed guidelines integrated into quality improvement initiatives reduce pediatric sepsis mortality and hospital length of stay. Our objective was to evaluate the quality of Canadian pediatric sepsis guidelines for children presenting to emergency departments (ED) and evaluate their consistency and concordance with the Surviving Sepsis guidelines (international reference standard).

Methods: We contacted all 15 Canadian pediatric hospitals and national organizations to obtain guidelines. Guidelines were included if they contained at least one recommendation on detection or management of pediatric sepsis in the ED. Two independent reviewers applied the AGREE-II tool to evaluate guideline quality (methodologic rigor). Quality was classified as high, moderate, or low based on published definitions. For each of the 12 ED-relevant recommendations from the reference standard, we calculated the percentage of all Canadian guidelines that provided the same recommendation (consistency). For each individual Canadian guideline, we calculated the percentage of the 12 recommendations that were the same as the reference standard (concordance).

Results: Nine guidelines were included. Guidelines were presented as pathway/algorithm, order set, narrative, or a combination of formats. Most institutional guidelines were of low quality, and a single national guideline was classified as high quality. Overall, guidelines were highly consistent across most recommendations of the reference standard, except for fluid bolus content (balanced vs normal saline). Similarly, individual guidelines were highly concordant with the reference standard, with only one low-quality guideline having a concordance of less than 80%.

Conclusion: The quality of Canadian institutional guidelines is low in terms of methodological development; however, recommendations in these guidelines remain generally consistent with an international reference standard, though key areas of inconsistency exist. Future efforts should focus on regularly reviewing and updating the robust national guideline that can be adapted to local institutional needs.

目的:脓毒症是影响儿童的一种常见且具有临床挑战性的危及生命的疾病。精心设计的指南与质量改进举措相结合,可降低儿童败血症死亡率和住院时间。我们的目的是评估加拿大儿科败血症指南的质量,并评估其与生存败血症指南(国际参考标准)的一致性和一致性。方法:我们联系了所有15家加拿大儿科医院和国家组织以获取指南。如果指南包含至少一项关于在急诊科检测或处理儿科败血症的建议,则纳入指南。两位独立审稿人使用AGREE-II工具评估指南质量(方法学严谨性)。根据公布的定义,质量被分为高、中、低三个等级。对于参考标准中12项ed相关建议中的每一项,我们计算了所有加拿大指南中提供相同建议的百分比(一致性)。对于每一个单独的加拿大指南,我们计算了12个建议中与参考标准相同的百分比(一致性)。结果:纳入9条指南。指南以路径/算法、顺序集、叙述或格式组合的形式呈现。大多数机构指南质量较低,只有一份国家指南被列为高质量指南。总的来说,指南与大多数参考标准的建议高度一致,除了液体丸含量(平衡与生理盐水)。同样,个别指南与参考标准高度一致,只有一个低质量指南的一致性低于80%。结论:加拿大机构指南在方法发展方面质量较低;然而,这些准则中的建议总体上与国际参考标准保持一致,尽管存在不一致的关键领域。今后的努力应侧重于定期审查和更新能够适应当地机构需要的强有力的国家指导方针。
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引用次数: 0
How health systems learn to fail : Emergency departments and the normalization of breakdown. 卫生系统如何学会失败:急诊科和崩溃的常态化。
IF 2 Pub Date : 2026-02-02 DOI: 10.1007/s43678-026-01090-w
Paul Atkinson, Alecs Chochinov, David Petrie
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引用次数: 0
Out-of-office, into manuscripts: how writing retreats fuel emergency medicine scholarship. 离职,入稿:如何写作退隐燃料急诊医学奖学金。
IF 2 Pub Date : 2026-02-02 DOI: 10.1007/s43678-026-01106-5
Jeffrey J Perry, Christian Vaillancourt, Krishan Yadav, Debra Eagles, Ian Stiell
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引用次数: 0
Predictors of bounce back for children redirected by triage nurses from the pediatric emergency department. 由儿科急诊科分诊护士重新指导的儿童反弹的预测因素。
IF 2 Pub Date : 2026-01-30 DOI: 10.1007/s43678-026-01099-1
Lorence Vanasse, Philippe Leduc, Geneviève Tourigny-Ruel, Corinne Thériault, Céline Pinard, Jocelyn Gravel

Objectives: To address crowding, our pediatric emergency department (ED) implemented a triage nurse-led protocol to redirect non-urgent patients to external pediatric clinics, other healthcare providers, family physicians, or home. This study aimed to identify the proportion of redirected children who returned to the ED and identify predictors of return.

Methods: We conducted a health records review study of children under 18 years redirected from the ED of a tertiary pediatric hospital in Montreal, Canada. A random sample of 150 return visits and 300 controls was selected for a nested case-control study. The primary outcome was a return visit to the ED within 7 days. Potential predictors included demographic information, disease characteristics, triage level, and initial orientation. We calculated the proportion of return visits and performed univariate and multivariable analyses of identified predictors.

Results: Between September 2023 and August 2024, 80,221 children were triaged, of whom 6,556 (8.2%) were redirected. Within 7 days, 372 (5.7%) returned. Among the 150 reviewed return visits, 127 (85%) were related to the initial complaint: 64 (43%) were due to persistent symptoms, 49 (33%) to clinical deterioration, 6 (4%) were sent back by a physician, and 5 (3%) were for new symptoms. Seven patients (4.7%) required hospitalization on their return visit. Predictors associated with a lower probability of return included ear, nose, throat, and dental complaints, as well as redirection to specialized or pediatric clinics.

Conclusions: Approximately, 6% of redirected children returned to the ED within 7 days, most often for persistent or worsening symptoms. Identifying predictors of return visits provides evidence to refine redirection guidelines and enhance the safety and effectiveness of triage nurse-led redirection strategies.

目的:为了解决拥挤问题,我们的儿科急诊科(ED)实施了一项由护士主导的分诊方案,将非紧急患者转移到外部儿科诊所、其他医疗保健提供者、家庭医生或家中。本研究旨在确定重定向儿童返回ED的比例,并确定返回的预测因素。方法:我们对来自加拿大蒙特利尔一家三级儿科医院急诊科的18岁以下儿童进行了健康记录回顾研究。随机抽取150名回访者和300名对照者进行巢式病例对照研究。主要结果是在7天内回访急诊科。潜在的预测因素包括人口统计信息、疾病特征、分诊水平和初始方向。我们计算了回访的比例,并对确定的预测因素进行了单变量和多变量分析。结果:2023年9月至2024年8月,共有80221名儿童进行了分诊,其中6556名(8.2%)进行了重定向。在7天内,372人(5.7%)返回。在回顾的150例回访中,127例(85%)与最初的主诉有关:64例(43%)是由于持续症状,49例(33%)是由于临床恶化,6例(4%)是由医生送回来的,5例(3%)是由于新的症状。7名患者(4.7%)回访时需要住院治疗。与较低复诊概率相关的预测因子包括耳鼻喉和牙科疾病,以及转到专科或儿科诊所。结论:大约6%的重定向儿童在7天内返回急诊科,大多数是持续或恶化的症状。确定复诊的预测因素为完善重定向指南和提高分诊护士主导的重定向策略的安全性和有效性提供了证据。
{"title":"Predictors of bounce back for children redirected by triage nurses from the pediatric emergency department.","authors":"Lorence Vanasse, Philippe Leduc, Geneviève Tourigny-Ruel, Corinne Thériault, Céline Pinard, Jocelyn Gravel","doi":"10.1007/s43678-026-01099-1","DOIUrl":"https://doi.org/10.1007/s43678-026-01099-1","url":null,"abstract":"<p><strong>Objectives: </strong>To address crowding, our pediatric emergency department (ED) implemented a triage nurse-led protocol to redirect non-urgent patients to external pediatric clinics, other healthcare providers, family physicians, or home. This study aimed to identify the proportion of redirected children who returned to the ED and identify predictors of return.</p><p><strong>Methods: </strong>We conducted a health records review study of children under 18 years redirected from the ED of a tertiary pediatric hospital in Montreal, Canada. A random sample of 150 return visits and 300 controls was selected for a nested case-control study. The primary outcome was a return visit to the ED within 7 days. Potential predictors included demographic information, disease characteristics, triage level, and initial orientation. We calculated the proportion of return visits and performed univariate and multivariable analyses of identified predictors.</p><p><strong>Results: </strong>Between September 2023 and August 2024, 80,221 children were triaged, of whom 6,556 (8.2%) were redirected. Within 7 days, 372 (5.7%) returned. Among the 150 reviewed return visits, 127 (85%) were related to the initial complaint: 64 (43%) were due to persistent symptoms, 49 (33%) to clinical deterioration, 6 (4%) were sent back by a physician, and 5 (3%) were for new symptoms. Seven patients (4.7%) required hospitalization on their return visit. Predictors associated with a lower probability of return included ear, nose, throat, and dental complaints, as well as redirection to specialized or pediatric clinics.</p><p><strong>Conclusions: </strong>Approximately, 6% of redirected children returned to the ED within 7 days, most often for persistent or worsening symptoms. Identifying predictors of return visits provides evidence to refine redirection guidelines and enhance the safety and effectiveness of triage nurse-led redirection strategies.</p>","PeriodicalId":93937,"journal":{"name":"CJEM","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with emergency department length of stay in Alberta: a study of patient-, visit-, and facility-level factors using administrative health data. 与阿尔伯塔省急诊科住院时间相关的因素:使用行政健康数据对患者、就诊和设施水平因素的研究。
IF 2 Pub Date : 2026-01-29 DOI: 10.1007/s43678-026-01093-7
Eddy Lang, Brian R Holroyd, Matthew Pietrosanu, Alice P Y Chiu, Darren Mazzei, Niloofar Taghizadeh, Shawn Dowling, Terrence McDonald, Michael Sidra

Purpose: The primary objective is to evaluate associations between emergency department (ED) total length of stay in Alberta and multiple patient-, visit-, and facility-level factors known to contribute to overcrowding and healthcare inefficiencies. This work aims to inform ongoing efforts to optimize ED performance and patient flow and, to our knowledge, is the largest population-based Canadian study examining associations with ED length of stay at multiple levels.

Methods: We conducted a cross-sectional study of 587,419 ED visits from 14 facilities in Alberta between May 2022 and March 2023 using administrative health data from Alberta Health Services, linked to the National Ambulatory Care Reporting System. Multivariable negative binomial regression was used to examine associations between ED length of stay and patient-, visit-, and facility-level characteristics. Analyses were stratified by patient disposition (admitted, discharged, or other).

Results: Older age, greater material or social deprivation, and any mode of emergency medical services transport were associated with longer ED length of stay across all disposition categories. Higher hospital inpatient occupancy rate and a greater number of emergency inpatients were associated with increased length of stay, particularly for admitted patients. Higher nurse staffing rates were associated with shorter length of stay, though this association disappeared when accounting for random differences between facilities. Higher patient continuity to physician was associated with a lower length of stay, suggesting a potential benefit of primary care integration.

Conclusions: ED length of stay is associated with modifiable factors, including hospital capacity constraints, hours worked per nurse, and healthcare access inequities. Addressing hospital occupancy, optimizing staffing, and improving care coordination across the patient trajectory-such as between the ED, inpatient units, and post-discharge services-may enhance ED efficiency and reduce prolonged stays. Our findings align with established frameworks describing ED overcrowding and support targeted, system-level interventions to improve the efficiency of emergency care.

目的:主要目的是评估阿尔伯塔省急诊科(ED)总住院时间与已知导致过度拥挤和医疗效率低下的多种患者、就诊和设施水平因素之间的关系。这项工作旨在为正在进行的优化ED表现和患者流量的工作提供信息,据我们所知,这是加拿大最大的基于人群的研究,研究了ED住院时间在多个层面上的关系。方法:我们对2022年5月至2023年3月期间来自艾伯塔省14家机构的587,419例急诊科就诊进行了横断面研究,使用了与国家门诊护理报告系统相关的艾伯塔省卫生服务部门的行政卫生数据。多变量负二项回归用于检查急诊科住院时间与患者、就诊和设施水平特征之间的关系。分析按患者倾向(入院、出院或其他)分层。结果:在所有处置类别中,年龄较大,物质或社会剥夺程度较大,以及任何紧急医疗服务运输模式与急诊科住院时间较长有关。较高的住院病人入住率和较多的急诊住院病人与住院时间延长有关,特别是住院病人。较高的护士配备率与较短的住院时间有关,尽管当考虑到设施之间的随机差异时,这种联系就消失了。较高的患者对医生的连续性与较短的住院时间相关,表明初级保健整合的潜在益处。结论:急诊科住院时间与可修改的因素有关,包括医院容量限制、每位护士的工作时间和医疗保健机会不平等。解决医院入住率、优化人员配置和改善整个患者轨迹(如急诊科、住院病房和出院后服务之间)的护理协调,可以提高急诊科的效率并减少延长住院时间。我们的研究结果与描述急诊科过度拥挤的既定框架一致,并支持有针对性的系统级干预措施,以提高急诊护理的效率。
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引用次数: 0
Optimizing care for patients who have ascites: shifting paracentesis from the emergency department to outpatient medicine. 优化对腹水患者的护理:将穿刺从急诊科转移到门诊。
IF 2 Pub Date : 2026-01-28 DOI: 10.1007/s43678-026-01095-5
Laurent Dubé, Francis Dubé, Celine Fresne
{"title":"Optimizing care for patients who have ascites: shifting paracentesis from the emergency department to outpatient medicine.","authors":"Laurent Dubé, Francis Dubé, Celine Fresne","doi":"10.1007/s43678-026-01095-5","DOIUrl":"https://doi.org/10.1007/s43678-026-01095-5","url":null,"abstract":"","PeriodicalId":93937,"journal":{"name":"CJEM","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146069468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Just the facts: damage control resuscitation in pediatric trauma. 事实是:儿童创伤的损伤控制复苏。
IF 2 Pub Date : 2026-01-18 DOI: 10.1007/s43678-025-01075-1
Sarah Redhwan, Salim Al Masroori, Suzanne Beno, Joe Nemeth
{"title":"Just the facts: damage control resuscitation in pediatric trauma.","authors":"Sarah Redhwan, Salim Al Masroori, Suzanne Beno, Joe Nemeth","doi":"10.1007/s43678-025-01075-1","DOIUrl":"https://doi.org/10.1007/s43678-025-01075-1","url":null,"abstract":"","PeriodicalId":93937,"journal":{"name":"CJEM","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study. 临床护理人员在症状发作后3小时内静脉注射奈奈肽治疗急性脑缺血的疗效和安全性(FRONTIER):一项多中心、随机、双盲、安慰剂对照的2期研究。
IF 2 Pub Date : 2026-01-16 DOI: 10.1007/s43678-025-01077-z
Mathieu McKinnon, Emma Ferguson, Jeffrey J Perry
{"title":"Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study.","authors":"Mathieu McKinnon, Emma Ferguson, Jeffrey J Perry","doi":"10.1007/s43678-025-01077-z","DOIUrl":"https://doi.org/10.1007/s43678-025-01077-z","url":null,"abstract":"","PeriodicalId":93937,"journal":{"name":"CJEM","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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