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Deutsche medizinische Wochenschrift (1946)最新文献

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[Gastrointestinal infections].
Pub Date : 2025-02-01 Epub Date: 2025-01-29 DOI: 10.1055/a-2304-3502
Siegbert Rieg, Robert Thimme
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引用次数: 0
[The gastrointestinal microbiome - vision and mission].
Pub Date : 2025-02-01 Epub Date: 2025-01-29 DOI: 10.1055/a-2303-3368
Andreas Stallmach

The gastrointestinal microbiome influences physiological functions and is altered in a variety of diseases. The causality of "dysbiosis" in the pathogenesis is not always proven; association studies are often involved. Patients with IBD, bacteria, fungi, bacteriophages, and archaea show disease-typical patterns associated with metabolome disturbances. Fecal microbiome transfer (FMT) for treating various diseases is the subject of numerous clinical studies. Currently, recurrent Clostridioides difficile infection (rCDI) is the only confirmed indication recommended in medical guidelines. In Germany, the FMT is subject to the Medicines Act and may only be carried out as part of individual healing attempts or clinical studies. For patient safety, repeated donor screening, ideally with the construction of a chair bench, is necessary. This significantly limits the nationwide availability of the FMT in Germany. Microbiota-based therapeutics prepared from the stool of tested donors have recently been approved by the US Food and Drug Administration (FDA) for the prevention of rCDI. More microbiome-based medicines can be expected in the future.

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引用次数: 0
[A case of measles pneumonia in a previously healthy adult].
Pub Date : 2025-02-01 Epub Date: 2025-02-12 DOI: 10.1055/a-2423-1796
Robin Habermann, Stefan Schmiedel

A 46-year-old male presented at the emergency department with a 2-day history of a fever up to 40°C, exertional dyspnea and a rash. The patient was on holiday in Greece up until a week prior to the development of symptoms.A chest CT scan showed an atypical pneumonia and marked lymphadenopathy. The detection of measles virus RNA led to the diagnosis of measles as a cause of the pneumonia.The patient was admitted to the hospital and received symptom-based treatment. He received temporary supplemental oxygen for mild hypoxemia.Any patients presenting with typical symptoms of measles (fever, rash, conjunctivitis) should be tested for it (serology, PCR), regardless of the patients' age.

{"title":"[A case of measles pneumonia in a previously healthy adult].","authors":"Robin Habermann, Stefan Schmiedel","doi":"10.1055/a-2423-1796","DOIUrl":"https://doi.org/10.1055/a-2423-1796","url":null,"abstract":"<p><p>A 46-year-old male presented at the emergency department with a 2-day history of a fever up to 40°C, exertional dyspnea and a rash. The patient was on holiday in Greece up until a week prior to the development of symptoms.A chest CT scan showed an atypical pneumonia and marked lymphadenopathy. The detection of measles virus RNA led to the diagnosis of measles as a cause of the pneumonia.The patient was admitted to the hospital and received symptom-based treatment. He received temporary supplemental oxygen for mild hypoxemia.Any patients presenting with typical symptoms of measles (fever, rash, conjunctivitis) should be tested for it (serology, PCR), regardless of the patients' age.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 5","pages":"207-210"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Career and family in residency]. [住院医生的职业与家庭]。
Pub Date : 2025-02-01 Epub Date: 2025-02-12 DOI: 10.1055/a-2313-5392
Stefan Frantz
{"title":"[Career and family in residency].","authors":"Stefan Frantz","doi":"10.1055/a-2313-5392","DOIUrl":"https://doi.org/10.1055/a-2313-5392","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 5","pages":"181"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The older patient in intensive care].
Pub Date : 2025-02-01 Epub Date: 2025-02-12 DOI: 10.1055/a-2286-6585
Hans Jürgen Heppner, Haitham Hag

Demographic trends mean that the proportion of older and very old patients in hospitals at all levels of care is increasing. This means that significantly more patients from these age groups can be expected in the future. These developments pose new challenges for both medical care and the management of geriatric intensive care patients, taking into account their multimorbidity and functional limitations due to acute illness. Although mortality increases with age, the outcome is highly dependent on the patient's functionality and comorbidity. The elderly patient also shows structural and functional organ changes, knowledge of which is important for the treatment of geriatric patients in intensive care medicine. This increasing need for geriatric treatment will have a decisive influence on the development of intensive care medicine in the coming years.

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引用次数: 0
[Sonography of the pleura - step by step].
Pub Date : 2025-02-01 Epub Date: 2025-02-12 DOI: 10.1055/a-2317-4447
Maximilian Zimmermann, Stephan Walterspacher

Pleural ultrasonography enables the rapid and reliable detection of pneumothoraces, pleural effusions, and other lung pathologies. Its advantages - such as high image resolution and ease of bedside use - make it particularly popular in acute and intensive care medicine. Despite its limitations in examining deeper structures, it offers many benefits compared to other imaging modalities.

胸膜超声造影能快速、可靠地检测气胸、胸腔积液和其他肺部病变。它具有图像分辨率高、床旁使用方便等优点,因此在急诊和重症监护领域特别受欢迎。尽管在检查深层结构方面存在局限性,但与其他成像方式相比,它仍有许多优点。
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引用次数: 0
[40-year-old female patient with nausea and vomiting for 3 days]. [40岁女性患者,恶心呕吐3天]。
Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2382-5289
Karsten Müssig
{"title":"[40-year-old female patient with nausea and vomiting for 3 days].","authors":"Karsten Müssig","doi":"10.1055/a-2382-5289","DOIUrl":"https://doi.org/10.1055/a-2382-5289","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"13-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Arthropathy as the first manifestation of undiagnosed hemochromatosis: a case report on an unusual course]. [关节病作为未确诊血色沉着病的首发症状:一个不寻常病程的病例报告]。
Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2422-9683
Hoxha Besjana, Jörn M Schattenberg, Konstantinos Triantafyllias

A 54-year-old man presented with increasing arthralgia and swelling of the metacarpophalangeal (MCP) joints II and III for approximately 2 years. He also reported morning stiffness and joint pain in both knees and feet.Both MCP joints II and III and the proximal interphalangeal joints II and III were tender without visible swelling. X-rays of the hands showed symmetrical osteoarthritic changes of the MCP joints I-III on both sides. Joint ultrasound revealed symmetrical osteophyte formation without inflammatory signs. Laboratory tests showed elevated ferritin (1436µg/l), iron (252µg/dl), and transferrin saturation (79%). Genetic testing confirmed a homozygous C282Y mutation, and FibroScan elastography indicated advanced fibrosis.Hemochromatosis-associated arthropathy.A symptom-oriented analgesic treatment with Metamizole was initiated. During the hospital stay, the patient received physical and occupational therapy. Hepatology specialists will manage further treatment at a university center, and the outcome remains to be seen.Symmetrical involvement of the MCP joints II and III should raise suspicion of hemochromatosis.

54岁男性,表现为II和III型掌指关节(MCP)关节痛和肿胀加重约2年。他还报告早晨僵硬,双膝和双脚关节疼痛。MCP关节II、III及近端指间关节II、III均有触痛,无明显肿胀。手部x光片显示两侧MCP关节I-III的对称骨关节炎改变。关节超声示对称骨赘形成,无炎症征象。实验室检测显示铁蛋白(1436µg/l)、铁(252µg/dl)和转铁蛋白饱和度(79%)升高。基因检测证实纯合子C282Y突变,纤维扫描弹性成像显示晚期纤维化。Hemochromatosis-associated关节病。开始了以症状为导向的止痛治疗。在住院期间,患者接受了物理和职业治疗。肝病专家将在大学中心进行进一步治疗,结果还有待观察。MCP关节II和III的对称受累应引起血色素沉着症的怀疑。
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引用次数: 0
[57-year-old male with fever, chills and whole-body pain]. [男,57岁,发热,畏寒,全身疼痛]。
Pub Date : 2025-01-01 Epub Date: 2025-01-14 DOI: 10.1055/a-2410-5639
Jonas Lohmann, Nils Kellner, Christoph Lübbert
{"title":"[57-year-old male with fever, chills and whole-body pain].","authors":"Jonas Lohmann, Nils Kellner, Christoph Lübbert","doi":"10.1055/a-2410-5639","DOIUrl":"https://doi.org/10.1055/a-2410-5639","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 3","pages":"75-76"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[(Surviving) life with cancer: the importance of sport and physical activity]. 癌症患者的生存:运动和体育活动的重要性。
Pub Date : 2025-01-01 Epub Date: 2024-12-11 DOI: 10.1055/a-2261-6310
Muriel Breuer, Stefan Brunner, Lutz Linneweber, Sebastian Theurich

As the survival prognosis of cancer patients continues to improve, the improvement in quality of life during and after cancer treatment is becoming increasingly important 1. Exercise therapy has a positive effect on so-called "patient-reported outcomes" 2. The combination of endurance training and individualized strength training plays a particularly important role here. There is therefore a need for consistent and comprehensive implementation of quality-assured exercise therapy in everyday clinical practice.

随着癌症患者生存预后的不断改善,癌症治疗期间和治疗后生活质量的提高变得越来越重要。运动疗法对所谓的“患者报告的结果”有积极影响。耐力训练和个体化力量训练的结合在这里起着特别重要的作用。因此,在日常临床实践中需要一致和全面地实施有质量保证的运动疗法。
{"title":"[(Surviving) life with cancer: the importance of sport and physical activity].","authors":"Muriel Breuer, Stefan Brunner, Lutz Linneweber, Sebastian Theurich","doi":"10.1055/a-2261-6310","DOIUrl":"https://doi.org/10.1055/a-2261-6310","url":null,"abstract":"<p><p>As the survival prognosis of cancer patients continues to improve, the improvement in quality of life during and after cancer treatment is becoming increasingly important 1. Exercise therapy has a positive effect on so-called \"patient-reported outcomes\" 2. The combination of endurance training and individualized strength training plays a particularly important role here. There is therefore a need for consistent and comprehensive implementation of quality-assured exercise therapy in everyday clinical practice.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 1-02","pages":"22-28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Deutsche medizinische Wochenschrift (1946)
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