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Editorial: Impact of parental education and socio-economic status on children's oral health behaviors. 社论:父母教育和社会经济地位对儿童口腔健康行为的影响。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1755103
Eman K M Mansur, Marilynn L Rothen, Sherry Shiqian Gao
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引用次数: 0
Temperature-related atypical first-bite syndrome: a rare case report. 与温度有关的非典型第一口综合征:罕见病例报告。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-11 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1678707
Zuntai Li, Ke Zhang, Yifan Dong, Zihui Wang, Chunxia Zhang, Long Su, Bo Zhao

First bite syndrome (FBS) manifests is characterized by severe parotid pain triggered by the first bite of food, with or without muscle spasms. The pain typically diminishes with subsequent bites. We report a case of 32-year-old male with Marcus-Gunn syndrome (30-year history), no prior head or neck surgery, tumors, infections, or temporomandibular joint disease. Since age of 15, he experiences bilateral parotid pain and spasms exclusively upon consuming ice cream in high ambient temperatures post-summer exercise. Symptoms resolve spontaneously within 30 s and persist despite trials of heat therapy, massage, and physiotherapy. While approximately 42% of FBS cases have identifiable etiology, others implicate aberrant activity in the auriculotemporal, greater auricular, or cervical sympathetic nerves. In this patient, symptoms occur only with cold food ingestion in hot environments, suggesting involvement of the trigeminal nerve's mandibular branch in oral thermosensation. To our knowledge, this is the first reported case linking FBS symptoms to temperature sensation.

第一咬综合征(FBS)表现为第一口食物引起的严重腮腺疼痛,伴有或不伴有肌肉痉挛。疼痛通常会随着随后的咬伤而减轻。我们报告一例32岁男性Marcus-Gunn综合征(30年病史),既往无头颈部手术、肿瘤、感染或颞下颌关节疾病。从15岁开始,他就有双侧腮腺疼痛和痉挛的症状,只有在夏季运动后的高温环境中吃冰淇淋时才会出现。症状在30秒内自行消退,尽管热疗、按摩和物理治疗的试验仍持续存在。虽然大约42%的FBS病例有明确的病因,但其他病例可能涉及耳颞神经、耳大神经或颈交感神经的异常活动。本例患者仅在高温环境下食用冷食时出现症状,提示三叉神经下颌支参与口腔热感觉。据我们所知,这是第一例将FBS症状与体温感觉联系起来的报告病例。
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引用次数: 0
Evidence on the association of overall dietary factors, selected environmental, medical, demographic, and biological factors and developmental defects of enamel, including MIH and enamel fluorosis. 总体饮食因素、选定的环境、医学、人口和生物因素与牙釉质发育缺陷(包括MIH和牙釉质氟中毒)相关的证据。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-11 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1616109
L Al Dehailan, E A Martinez-Mier

Introduction: Developmental defects of enamel (DDE) encompass a spectrum of conditions that occur during tooth formation, including enamel fluorosis, molar-incisor hypomineralization (MIH), and other forms of enamel hypoplasia. It has been proposed that DDE are associated with nutritional deficiencies as well as environmental exposures during tooth development.

Objective: This scoping review summarized and analyzed the evidence on the association between dietary habits, environmental exposures, medical/health-related factors, demographic factors and biological factors and DDE aiming to provide a comprehensive overview of the available evidence in this area.

Methodology: Following the Joanna Briggs Institute (JBI) framework using Population, Concept, and Context (PCC) to guide the development of the research question and eligibility. The population of interest were individuals from any age group or gender diagnosed with DDE. The eligibility concepts were factors that may contribute to DDE such as dietary and environmental exposures. The study selection followed the PRISMA guidelines. Studies published from January 1993 to December 2024 were identified through searches in Web of Science and PubMed.

Results: Our review included 125 studies from 1993 to 2024, mainly on fluorosis (105 studies), mostly cross-sectional, and conducted in Asia and North America. Fewer studies addressed MIH (5) and other non-fluorosis DDE (15), primarily in Europe, South America, and Asia, with most participants being children aged 6-12 years, and small sample sizes. The review evaluated DDE and its main subtypes, molar-incisor hypomineralization (MIH) and enamel fluorosis across conditions, overlapping risk factors were identified, such as excessive fluoride intake, vitamin D deficiency, early childhood illnesses, and exposure to environmental contaminants. Condition-specific patterns were also noted, fluorosis being primarily associated with high fluoride exposure and early weaning, whereas MIH was more frequently linked to vitamin D deficiency and early systemic.

Conclusion: The findings highlight that enamel fluorosis, MIH, and other enamel hypoplasias are part of a shared continuum of DDE influenced by interrelated dietary, environmental, and biological factors. These findings suggest common developmental pathways leading to enamel disruption and emphasize the need for longitudinal and mechanistic studies to clarify causal relationships and inform preventive strategies.

牙釉质发育缺陷(DDE)包括在牙齿形成过程中发生的一系列情况,包括牙釉质氟中毒、臼齿-门牙低矿化(MIH)和其他形式的牙釉质发育不全。有人提出,DDE与营养缺乏以及牙齿发育过程中的环境暴露有关。目的:本综述对饮食习惯、环境暴露、医疗/健康相关因素、人口因素和生物因素与DDE之间关系的证据进行了总结和分析,旨在对该领域现有证据进行全面概述。方法:遵循乔安娜布里格斯研究所(JBI)的框架,使用人口,概念和背景(PCC)来指导研究问题和资格的发展。所研究的人群是诊断为DDE的任何年龄组或性别的个体。资格概念是可能导致DDE的因素,如饮食和环境暴露。研究选择遵循PRISMA指南。从1993年1月到2024年12月发表的研究是通过Web of Science和PubMed的搜索确定的。结果:我们的综述包括1993年至2024年的125项研究,主要是氟中毒(105项研究),大多是横断面研究,在亚洲和北美进行。较少的研究涉及MIH(5)和其他非氟中毒DDE(15),主要在欧洲、南美和亚洲,大多数参与者是6-12岁的儿童,样本量小。该综述评估了DDE及其主要亚型,臼齿-门牙低矿化(MIH)和牙釉质氟中毒,确定了重叠的危险因素,如过量的氟化物摄入,维生素D缺乏,幼儿疾病和暴露于环境污染物。还注意到特定条件的模式,氟中毒主要与高氟化物暴露和早期脱机有关,而MIH则更经常与维生素D缺乏和早期全身性疾病有关。结论:研究结果强调,牙釉质氟中毒、MIH和其他牙釉质发育不良是DDE共同连续体的一部分,受相关饮食、环境和生物因素的影响。这些发现提示了导致牙釉质破坏的共同发育途径,并强调了纵向和机制研究的必要性,以阐明因果关系并为预防策略提供信息。
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引用次数: 0
Cerium chloride pretreatment reduces initial biofilm attachment on hydroxyapatite: a scanning electron microscopy study. 氯化铈预处理减少羟基磷灰石上的初始生物膜附着:扫描电镜研究。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-10 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1734138
Nils Gade, Konstantin J Scholz, Louis Kopp, Andreas Rosendahl, Wolfgang Buchalla, Annette Wiegand, Áine M Lennon

The incorporation of cerium instead of calcium into the crystal lattice of hydroxyapatite appears to increase the resistance of dental hard tissues to caries lesion initiation and progression. The effect on initial biofilm formation is yet unknown. The aim of this study was to assess the effect of cerium(III)chloride (50%CeCl3) pretreatment of hydroxyapatite (HA) discs on subsequent growth of an initial 3 species caries-biofilm. Twelve 9.5 mm diameter hydroxyapatite discs were divided into three groups (n = 4) and treated for 1 min with either 50% CeCl3, ultrapure water (Control), or 0.02% chlorhexidine gluconate (CHX) and washed twice in ultrapure water for 1 min. Samples were incubated in artificial saliva (21 °C, 120 min) for pellicle formation and then placed in an active attachment caries biofilm model comprising Actinomyces naeslundii, Schaalia odontolytica, and Streptococcus mutans, cultured anaerobically at 37 °C for 4 h before being fixed in 2.5% glutaraldehyde and examined using scanning electron microscopy (SEM) and energy dispersive x-ray analysis (EDX) in high-vacuum mode. SEM-micrographs at up to 50,000× showed net-like or spherical precipitates on the surface of all CeCl3-samples but not on the Control or CHX-samples. CeCl3-samples also showed signs of acid attack possibly due to the low pH (2.6) of the CeCl3 solution. Rods and cocci were found on all Control, but only on 2 of 4 CHX samples. On CeCl3 samples, only one harbored isolated cocci but no rods were observed. EDX-analyses confirmed the presence of Cerium in all CeCl3 samples with atomic percent (At%) ranging from 0.1 to 0.4 for areas without visible precipitates and up to 4.1 for areas with precipitates. CeCl3-treatment before pellicle formation results in the development of precipitates on the surface of HA and appears to have potential to inhibit initial biofilm growth on HA compared to CHX treated or untreated controls.

在羟基磷灰石的晶格中掺入铈而不是钙,似乎增加了牙齿硬组织对龋齿病变发生和发展的抵抗力。对初始生物膜形成的影响尚不清楚。本研究的目的是评估氯化铈(50%CeCl3)预处理羟基磷灰石(HA)盘对初始3种龋生物膜后续生长的影响。12个9.5 mm直径的羟基磷灰石盘分为3组(n = 4),分别用50% CeCl3、超纯水(对照)或0.02%葡萄糖酸氯己定(CHX)处理1 min,超纯水洗涤2次,处理1 min。样品在人工唾液中(21℃,120 min)孵育以形成膜,然后放置在由naeslundii放线菌、溶牙沙氏菌和变形链球菌组成的活性附着龋生物膜模型中,在37℃厌氧培养4小时,然后在2.5%戊二醛中固定,并在高真空模式下使用扫描电镜(SEM)和能量色散x射线分析(EDX)进行检测。高达5万倍的扫描电镜显微照片显示,所有cecl3样品表面都有网状或球形沉淀,而对照组或chx样品表面则没有。CeCl3样品也显示出酸侵蚀的迹象,这可能是由于CeCl3溶液的pH值(2.6)较低。在所有对照中均发现杆状体和球菌,但在4个CHX样本中仅发现2个。在CeCl3样品中,仅1个携带分离球菌,未观察到杆状体。edx分析证实了所有CeCl3样品中铈的存在,在没有可见沉淀物的区域,原子百分数(At%)在0.1到0.4之间,在有沉淀物的区域,原子百分数高达4.1。与CHX处理或未处理的对照相比,在膜形成之前处理cecl3会导致HA表面沉淀的发展,似乎有可能抑制HA上初始生物膜的生长。
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引用次数: 0
Integrating social science into oral health and dental research: a narrative review. 将社会科学纳入口腔健康和牙科研究:叙述性回顾。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-09 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1716748
Frederick Howard, Nawal Jama, Duangporn Duangthip

Oral health outcomes are shaped not only by biological and clinical factors but by social and structural conditions. This narrative review synthesizes social science contributions to oral health research published between 2015 and 2025, situating them within a longer history of interdisciplinary engagement. Foundational social science concepts have informed contemporary frameworks of dental public health, yet their methodological and theoretical integration remains limited. Relevant studies were identified in PubMed and AnthroSource. Peer-reviewed, English-language articles that substantively engage oral health through qualitative approaches were selected for inclusion. Drawing on methods such as interviews, focus groups, and ethnography, this body of research highlights how cultural frameworks, institutional barriers, and lived experiences shape oral health practices and outcomes. Across this literature, three purposes for integrating social science emerge: (1) adding interpretive depth to quantitative data; (2) analyzing how behavioral logics interact with structural constraints; and (3) improving outcomes through culturally responsive interventions. In our conceptual synthesis of this work, we argue for the continued development of bridge concepts (e.g., oral health fatalism, tooth shame, and status passage), which enable collaboration across disciplines by linking clinical practice to social context. Social science approaches expand explanatory frameworks, deepen contextual understanding, and illuminate oral health as a social and ethical phenomenon. By moving beyond methodological borrowing toward co-production of knowledge, interdisciplinary collaboration can more effectively address oral health inequities and support the development of care that is both scientifically rigorous and socially responsive.

口腔健康结果不仅受到生物学和临床因素的影响,而且受到社会和结构条件的影响。这篇叙述性综述综合了2015年至2025年间发表的口腔健康研究的社会科学贡献,将它们置于更长的跨学科参与历史中。基本的社会科学概念已经为当代牙科公共卫生框架提供了信息,但它们的方法和理论整合仍然有限。相关研究已在PubMed和AnthroSource中找到。经同行评议的、通过定性方法实质性涉及口腔健康的英文文章入选。利用访谈、焦点小组和人种学等方法,这一研究机构强调了文化框架、制度障碍和生活经历如何塑造口腔健康实践和结果。在这些文献中,整合社会科学出现了三个目的:(1)增加定量数据的解释深度;(2)分析行为逻辑与结构约束的相互作用;(3)通过文化响应性干预措施改善结果。在我们对这项工作的概念综合中,我们主张继续发展桥梁概念(例如,口腔健康宿命论,牙齿羞耻和地位通道),通过将临床实践与社会背景联系起来,实现跨学科合作。社会科学方法扩展了解释框架,加深了对上下文的理解,并将口腔健康阐明为一种社会和伦理现象。通过超越方法上的借鉴,转向知识的共同生产,跨学科合作可以更有效地解决口腔卫生不公平问题,并支持发展既科学严谨又符合社会需求的护理。
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引用次数: 0
Evaluation of an oral health program for children in San Francisco de Macorís, Dominican Republic (2019-2024). 多米尼加共和国旧金山Macorís儿童口腔健康项目评估(2019-2024)。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-09 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1671953
David Ribas-Perez, Carlos Muñoz-Viveros, Angel Luis Formoso-Veloso, Francisco Jesus Carrillo-Sanchez, Antonio Castaño-Seiquer

Introduction: Oral diseases remain a public health concern in the Dominican Republic, with epidemiological data indicating greater severity compared to other countries with similar geo-economic profiles. Numerous organizations, both governmental and private, have been involved in addressing this issue. Various nonprofit organizations have implemented oral health initiatives in the form of programs aimed at mitigating this situation. However, these projects often lack validation through studies assessing their impact on oral health outcomes.

Objective: The objective of this study is to describe the oral health status of a pediatric population and its association with perceived quality of life, while also evaluating the impact of a specific oral health program conducted in the city of San Francisco de Macorís. The evaluation aims to identify areas for improvement in the program's design and implementation.

Methods: The oral health program was assessed over the period 2019-2024. Oral health status was measured using a World Health Organization (WHO)-based survey, and oral health-related quality of life was assessed with the culturally adapted Spanish version of the COHIP-19SF questionnaire. The impact of the program was analyzed using various health and quality-of-life indicators.

Results: At baseline in 2019, 94 children from three regions in the Dominican Republic were assessed. Over five years, the restoration index improved substantially from 31.4% to 86.2%, indicating better access to dental care. Quality of life, measured using the COHIP-SF19, also improved. Significant gains were seen in functional well-being, oral health, and self-image domains, while socio-emotional well-being remained unchanged. Overall, the total COHIP-SF19 score dropped by 4 points, reflecting a meaningful improvement in oral health-related quality of life.

Conclusion: The intervention significantly reduced primary tooth decay, improved treatment access, and enhanced children's oral health-related quality of life. These results support the value of sustained oral health programs in vulnerable communities.

口腔疾病仍然是多米尼加共和国的一个公共卫生问题,其流行病学数据表明,与具有类似地缘经济概况的其他国家相比,其严重程度更高。许多政府和私人组织都参与了处理这一问题。各种非营利组织已经以旨在缓解这种情况的项目形式实施了口腔健康倡议。然而,这些项目往往缺乏通过评估其对口腔健康结果影响的研究来验证。目的:本研究的目的是描述儿科人群的口腔健康状况及其与感知生活质量的关系,同时也评估在旧金山市Macorís进行的特定口腔健康计划的影响。评估旨在确定项目设计和实施中需要改进的领域。方法:对2019-2024年口腔健康项目进行评估。口腔健康状况采用基于世界卫生组织(WHO)的调查进行测量,口腔健康相关生活质量采用西班牙语版COHIP-19SF问卷进行评估。使用各种健康和生活质量指标分析了该方案的影响。结果:以2019年为基准,对来自多米尼加共和国三个地区的94名儿童进行了评估。五年后,修复指数从31.4%大幅提高到86.2%,表明获得牙科保健的机会有所改善。使用COHIP-SF19测量的生活质量也有所改善。在功能健康、口腔健康和自我形象领域取得了显著的进步,而社会情感健康保持不变。总体而言,COHIP-SF19总分下降了4分,反映了口腔健康相关生活质量的显著改善。结论:干预可显著减少原发性蛀牙,改善治疗可及性,提高儿童口腔健康相关生活质量。这些结果支持了弱势群体持续口腔健康项目的价值。
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引用次数: 0
Prevalence and risk indicators of dental wear in a Saudi subpopulation. 沙特亚人群牙齿磨损的患病率和风险指标。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1702554
Ahmed A Madfa, Moazzy I Almansour, Mohammad D Aljanakh, Ahmed H Albaqawi, Sami A Almohefer, Saad M Al-Zubaidi, Sarah S Alajlan, Mohammed K Alsaleh, Ghaida A Alsulaiman, Faisal A Alzabni, Abdulelah S Alajlan

Background: The objective of this study was to investigate the prevalence of dental wear (DW) and evaluate potential contributing factors in the Hail province of Saudi Arabia.

Methods: A total of 386 individuals were involved in this cross-sectional study, which combined clinical assessments and questionnaire-based investigations. The clinical assessment using the Tooth Wear Index (TWI) was conducted. Each tooth was assigned a TWI score, and subsequently, individuals were classified into groups according to their level of risk. In addition to completing a demographic questionnaire, participants were also asked to respond to inquiries about their social, dietary, and dental health practices. The Chi-square test was used to investigate the association between the variables. The logistic regression analysis was also conducted to identify factors associated with tooth wear and its related clinical variables.

Results: A comprehensive examination was conducted on all 386 patients, revealing that 219 individuals (56.73%) exhibited observable indications of DW. The study sample exhibited a prevalence of dentin exposure accompanied by sensitivity at a rate of 97 cases, representing 25.6% of the total sample. In the current investigation, a total of 111 individuals, representing 28.8% of the sample, were identified as requiring dental care as a result of DW. There was a significant association between the severity of DW and variables such as age, sex, and educational level (p < 0.05). A significant correlation was observed between diet, oral health practices, and tooth wear (p < 0.05). The analysis highlights diet, systemic health, brushing timing, region/type of tooth wear, symptoms, and treatment needs as significant predictors of tooth wear.

Conclusions: The prevalence of DW in a Saudi subpopulation is relatively high. It is imperative that dentists provide guidance to their patients on oral hygiene habits and dietary selections that may contribute to significant tooth wear, as tooth wear is currently acknowledged as a substantial concern in the realm of oral health.

背景:本研究的目的是调查牙科磨损(DW)的患病率,并评估潜在的影响因素在沙特阿拉伯的冰雹省。方法:采用临床评估和问卷调查相结合的横断面研究方法,共纳入386例个体。采用牙齿磨损指数(TWI)进行临床评估。每颗牙齿都被分配了TWI评分,随后,根据他们的风险水平将个人分为不同的小组。除了完成一份人口调查问卷外,参与者还被要求回答有关他们的社交、饮食和牙齿健康习惯的问题。使用卡方检验来调查变量之间的相关性。并进行logistic回归分析,以确定与牙齿磨损相关的因素及其相关临床变量。结果:对386例患者进行全面检查,219例(56.73%)表现出可观察到的DW指征。研究样本显示,牙本质暴露伴随敏感性的患病率为97例,占总样本的25.6%。在目前的调查中,共有111人(占样本的28.8%)被确定为因DW而需要牙科护理。DW的严重程度与年龄、性别和教育水平等变量之间存在显著相关性(p)。结论:沙特亚人群中DW的患病率相对较高。牙医必须就可能导致牙齿严重磨损的口腔卫生习惯和饮食选择向患者提供指导,因为牙齿磨损目前被认为是口腔健康领域的一个重要问题。
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引用次数: 0
Editorial: Multidisciplinary management of oral cancer: diagnosis, treatment, and rehabilitation. 社论:口腔癌的多学科管理:诊断、治疗和康复。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1747684
Oreste Iocca, Camila Lopes Cardoso, Pasquale Di Maio
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引用次数: 0
Evaluating infra-orbital nerve injury in zygomaticomaxillary complex fractures: a systematic review and meta-analysis. 评估颧腋窝复合体骨折的眶下神经损伤:系统回顾和荟萃分析。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-05 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1726808
Unnati Bimal Mehta, Uday Londhe, Kalyani Bhate, Manoj Bafna, Somya Pande, Lakshmi Shetty

Aim: This systematic review aimed to assess infraorbital nerve (ION) injury in zygomatico-maxillary complex (ZMC) fractures, specifically examining the incidence, diagnostic approaches, and comparative efficacy of surgical vs. conservative management.

Methods: This review was completed in accordance with PRISMA 2020 principles and was recorded in PROSPERO (CRD42024545221). The Cochrane CENTRAL, Embase, MEDLINE, and PubMed databases were thoroughly examined between January 2015 and April 2025. Adult patients (≥18 years) with radiologically confirmed ZMC fractures who specifically reported infraorbital nerve outcomes, such as sensory abnormalities, diagnostic evaluations, and recovery after therapy, were eligible for inclusion in the studies. Cochrane RoB 2.0 for randomized trials and the modified Newcastle-Ottawa Scale for observational studies were used to assess the quality of the studies. RevMan 5.4 was used to carry out statistical pooling using a random-effects model.

Results: Initially, 457 articles were found in the literature search; duplicates were eliminated, titles and abstracts were screened, and 48 complete texts were examined; 13 studies (1,308 patients) met the inclusion criteria. The meta-analysis includes 11 trials with 802 patients. After ZMC fractures, the combined incidence of ION damage was 51.9% (95% CI: 48%-55%). When compared to conservative therapies, early surgical decompression (within two weeks after the damage) consistently produced superior sensory recovery. With little use of objective testing (blink reflex, current perception thresholds), diagnostic evaluations were mostly based on subjective measurements (two-point discrimination, pain thresholds).

Conclusion: Infraorbital nerve injury remains a prevalent complication in ZMC fractures, affecting approximately half of the patients. Surgical decompression performed early after injury significantly improves sensory recovery outcomes over conservative management. There remains substantial variability in diagnostic methods and outcome measurements, highlighting the need for standardized approaches. Future randomized controlled trials with robust methodologies and consistent outcome assessments are necessary to enhance clinical guidance and patient outcomes.

Systematic review registration: : ROSPERO CRD42024545221.

目的:本系统综述旨在评估颧骨-上颌复合体(ZMC)骨折中的眶下神经(ION)损伤,特别是检查手术与保守治疗的发生率、诊断方法和比较疗效。方法:本综述按照PRISMA 2020原则完成,并记录在PROSPERO (CRD42024545221)中。在2015年1月至2025年4月期间对Cochrane CENTRAL、Embase、MEDLINE和PubMed数据库进行了全面检查。影像学证实的ZMC骨折的成年患者(≥18岁)明确报告眶下神经预后,如感觉异常、诊断评估和治疗后恢复,符合纳入研究的条件。随机试验采用Cochrane RoB 2.0,观察性研究采用改良的Newcastle-Ottawa量表评估研究质量。采用RevMan 5.4,采用随机效应模型进行统计池化。结果:最初在文献检索中发现457篇文章;删除了重复,筛选了标题和摘要,审查了48篇全文;13项研究(1308例患者)符合纳入标准。荟萃分析包括11项试验,802名患者。ZMC骨折后,离子损伤的总发生率为51.9% (95% CI: 48%-55%)。与保守疗法相比,早期手术减压(损伤后两周内)始终能产生更好的感觉恢复。由于很少使用客观测试(眨眼反射,当前感知阈值),诊断评估主要基于主观测量(两点辨别,疼痛阈值)。结论:眶下神经损伤是ZMC骨折的常见并发症,约占患者的一半。与保守治疗相比,损伤后早期进行手术减压可显著改善感觉恢复结果。在诊断方法和结果测量方面仍然存在很大的可变性,突出了标准化方法的必要性。未来有必要进行随机对照试验,采用可靠的方法和一致的结果评估,以加强临床指导和患者预后。系统评价注册::ROSPERO CRD42024545221。
{"title":"Evaluating infra-orbital nerve injury in zygomaticomaxillary complex fractures: a systematic review and meta-analysis.","authors":"Unnati Bimal Mehta, Uday Londhe, Kalyani Bhate, Manoj Bafna, Somya Pande, Lakshmi Shetty","doi":"10.3389/froh.2025.1726808","DOIUrl":"10.3389/froh.2025.1726808","url":null,"abstract":"<p><strong>Aim: </strong>This systematic review aimed to assess infraorbital nerve (ION) injury in zygomatico-maxillary complex (ZMC) fractures, specifically examining the incidence, diagnostic approaches, and comparative efficacy of surgical vs. conservative management.</p><p><strong>Methods: </strong>This review was completed in accordance with PRISMA 2020 principles and was recorded in PROSPERO (CRD42024545221). The Cochrane CENTRAL, Embase, MEDLINE, and PubMed databases were thoroughly examined between January 2015 and April 2025. Adult patients (≥18 years) with radiologically confirmed ZMC fractures who specifically reported infraorbital nerve outcomes, such as sensory abnormalities, diagnostic evaluations, and recovery after therapy, were eligible for inclusion in the studies. Cochrane RoB 2.0 for randomized trials and the modified Newcastle-Ottawa Scale for observational studies were used to assess the quality of the studies. RevMan 5.4 was used to carry out statistical pooling using a random-effects model.</p><p><strong>Results: </strong>Initially, 457 articles were found in the literature search; duplicates were eliminated, titles and abstracts were screened, and 48 complete texts were examined; 13 studies (1,308 patients) met the inclusion criteria. The meta-analysis includes 11 trials with 802 patients. After ZMC fractures, the combined incidence of ION damage was 51.9% (95% CI: 48%-55%). When compared to conservative therapies, early surgical decompression (within two weeks after the damage) consistently produced superior sensory recovery. With little use of objective testing (blink reflex, current perception thresholds), diagnostic evaluations were mostly based on subjective measurements (two-point discrimination, pain thresholds).</p><p><strong>Conclusion: </strong>Infraorbital nerve injury remains a prevalent complication in ZMC fractures, affecting approximately half of the patients. Surgical decompression performed early after injury significantly improves sensory recovery outcomes over conservative management. There remains substantial variability in diagnostic methods and outcome measurements, highlighting the need for standardized approaches. Future randomized controlled trials with robust methodologies and consistent outcome assessments are necessary to enhance clinical guidance and patient outcomes.</p><p><strong>Systematic review registration: </strong>: ROSPERO CRD42024545221.</p>","PeriodicalId":94016,"journal":{"name":"Frontiers in oral health","volume":"6 ","pages":"1726808"},"PeriodicalIF":3.1,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12714943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145807127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Airways and malocclusion: etiology and treatment outcomes. 社论:气道和错颌:病因和治疗结果。
IF 3.1 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-05 eCollection Date: 2025-01-01 DOI: 10.3389/froh.2025.1733643
Michele Tepedino, Mauro Lorusso, Domenico Ciavarella

The correlation between the upper airway and malocclusion is still a controversial issue. Craniofacial abnormalities and dental malocclusions, such as mandibular retrusion, maxillary constriction, and vertical skeletal discrepancies, are strongly associated with reduced airway patency and increased pharyngeal collapsibility. This relationship underscores the importance of evaluating craniofacial morphology in both the diagnosis and management of OSAS. Treatment aims not only to reduce apneic events and improve sleep quality but also to restore normal breathing dynamics and prevent long-term cardiovascular, metabolic, and neurocognitive complications. Achieving these goals requires a multidisciplinary approach that integrates orthodontics, surgery, otolaryngology, and sleep medicine to provide effective and long-term outcomes.

上气道与错牙合的相关性仍然是一个有争议的问题。颅面异常和牙齿错颌,如下颌后缩、上颌收缩和垂直骨骼差异,与气道通畅减少和咽塌陷增加密切相关。这种关系强调了评估颅面形态学在OSAS诊断和治疗中的重要性。治疗的目的不仅是减少呼吸暂停事件和改善睡眠质量,而且要恢复正常的呼吸动力学,防止长期的心血管、代谢和神经认知并发症。实现这些目标需要多学科的方法,整合正畸,外科,耳鼻喉科和睡眠医学,以提供有效和长期的结果。
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引用次数: 0
期刊
Frontiers in oral health
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