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Validity and reliability of an immersive virtual reality adaptation of the 6-minute pegboard and ring test. 沉浸式虚拟现实改编版 6 分钟钉板和套环测试的有效性和可靠性。
Pub Date : 2024-10-30 DOI: 10.1016/j.hansur.2024.101981
Çağtay Maden, Demet Gözaçan Karabulut, Burcu Bağcı

Background and aim: Virtual reality offers new clinical assessment and rehabilitation options that can complement or, in some cases, replace traditional methods. However, the applicability of using virtual reality tools for assessment of upper limb functional capacity has not been fully explored. We therefore developed an immersive virtual reality adaptation of the 6-Minute Pegboard and Ring Test (6PBRT-VR). The aim of the study was to test the validity and reliability of the 6PBRT-VR for the assessment of upper extremity functional capacity, and to assess the performance and feasibility of the proposed tool.

Methods: Thirty healthy young adults were included in the study. The participants performed the classical 6-Minute Pegboard and Ring Test first and then the 6PBRT-VR. The test-retest reliability of the 6PBRT-VR was assessed on intraclass correlation coefficient. Concurrent validity was assessed on the correlation between the 6PBRT-VR test-retest scores (number of rings moved) and the correlation between the scores from the classical 6-Minute Pegboard and Ring Test and the 6PBRT-VR. Convergent validity was assessed on correlations with handgrip strength and the total Quick Disabilities of the Arm, Shoulder, and Hand score. Cardiorespiratory responses were also measured (at baseline and after each test). Perceived arm fatigue was assessed on the Modified Borg Scale.

Results: The 6PBRT-VR exhibited excellent test-retest reliability, with an intraclass correlation coefficient of 0.866 (95% confidence interval 0.737-0.934). Mean 6PBRT-VR score correlated strongly with the mean score of the classical 6-Minute Pegboard and Ring Test (r = 0.817, p < 0.001). A significant association was found between the 6PBRT-VR and the classical 6-Minute Pegboard and Ring Test in terms of variations in heart rate, systolic blood pressure, and Modified Borg Scale score (p < 0.001). Mean 6PBRT-VR score showed moderate correlations with right (r = 0.571, p = 0.001) and left handgrip strength (r = 0.550, p = 0.002).

Conclusion: The 6PBRT-VR is a reliable and valid virtual tool for assessing upper-extremity functional capacity in young adults.

背景和目的:虚拟现实技术提供了新的临床评估和康复选择,可以补充或在某些情况下替代传统方法。然而,使用虚拟现实工具评估上肢功能能力的适用性尚未得到充分探索。因此,我们开发了一种沉浸式虚拟现实技术,对 6 分钟钉板和套环测试(6PBRT-VR)进行改编。研究的目的是测试 6PBRT-VR 在评估上肢功能能力方面的有效性和可靠性,并评估所提议的工具的性能和可行性:研究对象包括 30 名健康的年轻人。方法:研究对象包括 30 名健康的年轻人,他们首先进行了经典的 6 分钟钉板和套环测试,然后进行了 6PBRT-VR 测试。根据类内相关系数评估 6PBRT-VR 的重测可靠性。并发效度是根据 6PBRT-VR 测试-再测得分(移动环数)与经典的 6 分钟钉板套环测试得分之间的相关性以及 6PBRT-VR 与 6PBRT-VR 之间的相关性进行评估的。根据与手握力和手臂、肩部和手部快速残疾总分的相关性评估了收敛有效性。此外,还测量了心肺反应(基线和每次测试后)。根据改良博格量表对手臂疲劳感进行了评估:结果:6PBRT-VR 的测试-重复测试可靠性极佳,类内相关系数为 0.866(95% 置信区间为 0.737-0.934)。6PBRT-VR 的平均得分与经典的 6 分钟钉板和套环测试的平均得分密切相关(r = 0.817,p 结论:6PBRT-VR 与经典的 6 分钟钉板和套环测试的平均得分密切相关:6PBRT-VR 是一种可靠有效的虚拟工具,可用于评估年轻成年人的上肢功能能力。
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引用次数: 0
Comparison of WALANT versus locoregional nerve block in staged bilateral endoscopic carpal tunnel release. 分期双侧内窥镜腕管松解术中 WALANT 与局部神经阻滞的比较。
Pub Date : 2024-10-30 DOI: 10.1016/j.hansur.2024.101974
Dries Verrewaere, Pieter Reyniers, Hanne Vandevivere, Filip Stockmans, Bart Berghs, Francis Bonte

Background: Carpal tunnel release can be performed as open or endoscopic surgery. In WALANT (wide awake local anesthesia no tourniquet) a tourniquet is not used, ensuring less discomfort for the patient. In locoregional distal nerve block, on the other hand, a tourniquet is needed and can be painful. This raises the question as to which method of anesthesia is actually preferred for the patient and the surgeon. Patients undergoing staged bilateral carpal tunnel release present a unique opportunity to study this question.

Methods: Fifteen patients were included in this prospective study. The primary endpoint was the preference for anesthesia type in patients and surgeons. Surgeon preference was based on the visibility and fluency of the procedure. Secondary endpoints for patients comprised pain scores for performing surgery and anesthesia and pain caused by the tourniquet.

Results: Baseline demographic and clinical information was collected. There was no significant difference in pain for performing local anesthesia or surgery. Surgeons may find that performing endoscopic release under WALANT is more challenging, as visibility tends to be significantly poorer. The mean pain caused by the tourniquet used during the wrist block procedure was rated as 3.6. In both surgeries, 77% (10/13) of the patients preferred the WALANT anesthesia.

Conclusion: In general, endoscopic carpal tunnel release was better tolerated under WALANT than locoregional distal nerve block. Although statistical analysis showed no significant difference in visibility and fluency for the surgeon between the two anesthesia techniques, we do not recommend endoscopic release under WALANT due to the consistent report of reduced visibility in the surgical field. This limitation, likely related to the presence of anesthetic fluid, may have failed to reach statistical significance due to small sample size, but is nevertheless a considerable challenge in practice.

Level of evidence: 1B.

背景介绍腕管松解术可通过开放手术或内窥镜手术进行。在 WALANT(无止血带宽清醒局部麻醉)手术中,不使用止血带,可减少患者的不适感。而在局部远端神经阻滞术中,则需要使用止血带,而且会给患者带来痛苦。这就提出了一个问题,究竟哪种麻醉方法更适合患者和外科医生。接受分期双侧腕管松解术的患者为研究这一问题提供了独特的机会:这项前瞻性研究纳入了 15 名患者。主要终点是患者和外科医生对麻醉类型的偏好。外科医生的偏好基于手术的可视性和流畅性。患者的次要终点包括进行手术和麻醉时的疼痛评分以及止血带引起的疼痛:结果:收集了基线人口统计学和临床信息。进行局部麻醉或手术时的疼痛没有明显差异。外科医生可能会发现,在 WALANT 下进行内窥镜松解术更具挑战性,因为能见度往往明显较低。腕部阻滞手术中使用止血带造成的平均疼痛为 3.6 级。在这两次手术中,77%(10/13)的患者更倾向于使用 WALANT 麻醉:总的来说,与局部远端神经阻滞相比,在WALANT麻醉下进行内窥镜腕管松解术的耐受性更好。虽然统计分析显示两种麻醉技术在手术视野和手术流畅性方面没有明显差异,但由于手术视野视野降低的报告一直存在,我们不推荐在 WALANT 下进行内窥镜腕管松解术。这一局限性可能与麻醉液的存在有关,可能由于样本量较小而未能达到统计学意义,但在实践中仍是一个相当大的挑战:1B.
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引用次数: 0
Hand therapy for a dorsal wrist ganglion cyst, monitored with ultrasound imaging. 腕背神经节囊肿的手部治疗,超声波成像监控。
Pub Date : 2024-10-30 DOI: 10.1016/j.hansur.2024.101973
Tom Lattré, Arne Decramer
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引用次数: 0
A new high-frequency ultrasound classification of De Quervain tenosynovitis. 杜氏腱鞘炎的新型高频超声波分类法
Pub Date : 2024-10-30 DOI: 10.1016/j.hansur.2024.101975
Xiaoliang Yang, Xu Zhang, Xiuqing Ma, Mei Han, Yadong Yu, Shijun Mi

Purpose: This study aimed to introduce a new high-frequency ultrasound classification of De Quervain tenosynovitis based on a large group of patients. Detailed characteristics of classification are also reported.

Methods: From January 2014 to February 2024, patients diagnosed with De Quervain tenosynovitis were retrospectively reviewed. High-frequency ultrasound (7-14 MHz) scanning was performed to identify the anatomy of the extensor pollicis brevis and abductor pollicis longus tendons, presence of intertendinous septa, and pathologic changes. The affected wrist was compared to the contralateral wrist.

Results: 453 patients were included: 65 male and 388 female; mean age, 46 ± 27 years (range, 24-65 years). Symptom duration was 14 ± 27 weeks. Disease types were type 0 (n = 5), type 1 (n = 195), type 2a (n = 72), type 2b (n = 18), type 2c (n = 50), type 3 (n = 59), type 4 (n = 45), and type 5 (n = 9). Mean retinacular thickness was 2.1 ± 0.5 mm in affected wrists and 0.4 ± 0.1 mm in contralateral wrists (p < 0.01). The intercompartmental septum was significantly thicker on the affected side (1.2 ± 0.7 mm) than on the asymptomatic side (0.1 ± 0.4 mm) (p < 0.01).

Conclusions: This novel classification provides detailed ultrasonographic characteristics of De Quervain tenosynovitis, based on a large population of patients. It may help in selecting treatment and predicting outcome. However, relevance and therapeutic significance remain to be demonstrated.

Level of evidence: Therapeutic study, Level IV.

目的:本研究旨在根据一大批患者的情况,介绍一种新的高频超声德奎文腱鞘炎分类法。方法:方法:回顾性分析 2014 年 1 月至 2024 年 2 月期间确诊为德奎恩腱鞘炎的患者。进行高频超声波(7-14 MHz)扫描,以确定伸拇肌和外展肌腱的解剖结构、肌腱间隔膜的存在以及病理变化。受影响的手腕与对侧手腕进行比较:结果:共纳入 453 名患者:结果:共纳入 453 名患者:65 名男性,388 名女性;平均年龄为 46±27 岁(范围为 24-65 岁)。症状持续时间为 14±27 周。疾病类型为0型(5人)、1型(195人)、2a型(72人)、2b型(18人)、2c型(50人)、3型(59人)、4型(45人)和5型(9人)。患病腕部的平均视网膜厚度为 2.1±0.5 毫米,对侧腕部的平均视网膜厚度为 0.4±0.1 毫米(P结论:这种新颖的分类方法基于大量患者,提供了德-夸尔曼氏腱鞘炎的详细超声特征。它有助于选择治疗方法和预测疗效。然而,其相关性和治疗意义仍有待证实:治疗研究,IV 级。
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引用次数: 0
Vascularized bone flaps from the hand and wrist. 手部和腕部血管化骨瓣
Pub Date : 2024-10-30 DOI: 10.1016/j.hansur.2024.101972
Germain Pomares, Amandine Ledoux

Vascularized bone flaps from the hand and wrist are an alternative to free bone transfer. Their obvious advantages recommend them for routine use. Indications and techniques should be known by hand surgeons.

手部和腕部血管化骨瓣是游离骨移植的一种替代方法。它们具有明显的优势,值得常规使用。手外科医生应了解其适应症和技术。
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引用次数: 0
Median nerve entrapment after supracondylar humeral fracture: An ultrasonographic view. 肱骨髁上骨折后的正中神经卡压:超声波检查。
Pub Date : 2024-10-29 DOI: 10.1016/j.hansur.2024.101970
Yakup Erden, Mustafa Hüseyin Temel, Mahmut Kurtboğan
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引用次数: 0
Anterior transfer of the long head of triceps nerve to the terminal part of the anterior division of the axillary nerve through two incisions: A cadaveric feasibility study. 通过两个切口将肱三头肌神经长头前移至腋神经前部末端:尸体可行性研究。
Pub Date : 2024-10-29 DOI: 10.1016/j.hansur.2024.101971
Jean-Noël Goubier, Tanguy Perraudin, Camille Echalier

Purpose: Restoring shoulder function after axillary nerve injury is always a challenge. Transferring a branch of the radial nerve destined to the triceps onto the anterior division of the axillary nerve has become the preferred technique. However, this is not always possible, especially when the axillary nerve is severely injured around the posterior part of the humeral neck. The purpose of this cadaver study was to assess the feasibility of transferring the nerve of the long head of the triceps through an anterior and lateral humeral neck tunnel, directly onto the branch of the anterior division of the distal axillary nerve where it enters the deltoid fibers, by two surgical approaches.

Materials and methods: This anatomical study was performed using 6 fresh cadavers (12 shoulders). A medial brachial approach was used to locate the radial nerve and its first branch, innervating the long head of the triceps. Then a second, transdeltoid approach was made to locate the end of the anterior branch near where it enters the deltoid fibers. The long head of the triceps nerve was transected as close as possible to the muscle, to provide the longest length possible. Then an anterior and lateral subdeltoid tunnel was made to retrieve this branch through the transdeltoid approach.

Results: The long head of the triceps nerve could always be sutured to the anterior branch of the axillary nerve. Given the 7-12 mm surplus length (mean, 8.8 mm), tensionless suturing was possible in an anatomical region amenable to easier microsurgery.

Discussion: Transfer of the long head of the triceps to the anterior branch of the axillary nerve through an axillary or posterior approach remains the preferred method for reinnervating the deltoid. However, in some patients, the axillary nerve is injured at or beyond the typical microsurgical suturing zone, which means that transfer cannot be accomplished under optimal conditions. For this reason, we suggest making the transfer more distally, using a dual approach that allows direct suturing of the long head of the triceps nerve onto the anterior terminal branch, which shortens the distance between the sutured nerve and the deltoid, and should improve outcome.

目的腋神经损伤后恢复肩部功能始终是一项挑战。将桡神经的肱三头肌分支转移到腋神经前部已成为首选技术。然而,这并不总是可行的,尤其是当腋神经在肱骨颈后部受到严重损伤时。这项尸体研究的目的是评估通过两种手术方法,将肱三头肌长头神经通过肱骨颈前侧和外侧隧道,直接转移到腋神经远端前分支进入三角肌纤维处的可行性:这项解剖研究使用了 6 具新鲜尸体(12 个肩膀)。采用肱骨内侧入路定位桡神经及其支配肱三头肌长头的第一支。然后进行第二次经三角肌入路,找到前支末端靠近三角肌纤维的位置。尽可能靠近肌肉横切肱三头肌神经长头,以获得尽可能长的长度。然后在三角肌下前侧和外侧开辟一条隧道,通过经三角肌入路取回该分支:结果:肱三头肌神经的长头始终可以与腋神经前支缝合。鉴于其剩余长度为7-12毫米(平均值为8.8毫米),可以在解剖区域内进行无张力缝合,使显微外科手术更加容易:讨论:通过腋窝或后方入路将肱三头肌长头转移至腋神经前支仍是三角肌再神经化的首选方法。然而,有些患者的腋神经损伤部位在显微外科缝合区或其范围之外,这意味着无法在最佳条件下完成转移。因此,我们建议在更远的位置进行转移,采用双重方法,将肱三头肌神经的长头直接缝合到前末端分支上,这样可以缩短缝合神经与三角肌之间的距离,从而改善手术效果。
{"title":"Anterior transfer of the long head of triceps nerve to the terminal part of the anterior division of the axillary nerve through two incisions: A cadaveric feasibility study.","authors":"Jean-Noël Goubier, Tanguy Perraudin, Camille Echalier","doi":"10.1016/j.hansur.2024.101971","DOIUrl":"10.1016/j.hansur.2024.101971","url":null,"abstract":"<p><strong>Purpose: </strong>Restoring shoulder function after axillary nerve injury is always a challenge. Transferring a branch of the radial nerve destined to the triceps onto the anterior division of the axillary nerve has become the preferred technique. However, this is not always possible, especially when the axillary nerve is severely injured around the posterior part of the humeral neck. The purpose of this cadaver study was to assess the feasibility of transferring the nerve of the long head of the triceps through an anterior and lateral humeral neck tunnel, directly onto the branch of the anterior division of the distal axillary nerve where it enters the deltoid fibers, by two surgical approaches.</p><p><strong>Materials and methods: </strong>This anatomical study was performed using 6 fresh cadavers (12 shoulders). A medial brachial approach was used to locate the radial nerve and its first branch, innervating the long head of the triceps. Then a second, transdeltoid approach was made to locate the end of the anterior branch near where it enters the deltoid fibers. The long head of the triceps nerve was transected as close as possible to the muscle, to provide the longest length possible. Then an anterior and lateral subdeltoid tunnel was made to retrieve this branch through the transdeltoid approach.</p><p><strong>Results: </strong>The long head of the triceps nerve could always be sutured to the anterior branch of the axillary nerve. Given the 7-12 mm surplus length (mean, 8.8 mm), tensionless suturing was possible in an anatomical region amenable to easier microsurgery.</p><p><strong>Discussion: </strong>Transfer of the long head of the triceps to the anterior branch of the axillary nerve through an axillary or posterior approach remains the preferred method for reinnervating the deltoid. However, in some patients, the axillary nerve is injured at or beyond the typical microsurgical suturing zone, which means that transfer cannot be accomplished under optimal conditions. For this reason, we suggest making the transfer more distally, using a dual approach that allows direct suturing of the long head of the triceps nerve onto the anterior terminal branch, which shortens the distance between the sutured nerve and the deltoid, and should improve outcome.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment of proximal interphalangeal joint stress fracture in a climber. 一名登山运动员近端指间关节应力性骨折的手术治疗。
Pub Date : 2024-10-10 DOI: 10.1016/j.hansur.2024.101790
Yuji Saeki, Mitsunori Shigetomi, Koji Yoshida, Yosuke Yamashita

Proximal interphalangeal joint stress fractures commonly occur as epiphyseal line injuries in teenage climbers; however, fractures with closed epiphyseal lines are rare. Poor outcomes are more common if treatment is delayed. We report the case of a 16-year-old climber who underwent delayed surgical treatment for a fracture with a closed epiphyseal line, with a favorable outcome. There was 20 ° extension lag at the proximal interphalangeal joint and a fracture on the dorsal aspect of the base of the metaphyseal bone, with osteosclerosis at the fracture site. The fracture site was refreshed and internal fixation was performed using the tension-band wiring technique. At 3 months postoperatively, there was no pain, extension had improved, and bone union was achieved. This case illustrates the effectiveness of surgery in achieving favorable outcomes for delayed proximal interphalangeal joint stress fractures in climbers with epiphyseal line closure. LEVEL OF EVIDENCE: V.

在青少年登山者中,近端指间关节应力性骨折常见于骺线损伤;然而,闭合性骺线骨折却很少见。如果延误治疗,则更容易出现不良后果。我们报告了一个 16 岁登山者的病例,他因闭合性骺线骨折而接受了延迟手术治疗,结果良好。该患者近端指间关节有 20 °的伸展滞后,骨骺基底背侧有骨折,骨折部位有骨质硬化。对骨折部位进行了翻修,并采用张力带接线技术进行了内固定。术后 3 个月,患者无疼痛感,伸展情况有所改善,并实现了骨结合。本病例说明了手术在治疗骺线闭合的登山者近端指间关节延迟性应力性骨折方面的有效性。证据等级:V.
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引用次数: 0
Ultrasound-guided radial nerve release at the arm under WALANT. WALANT 下超声引导的手臂桡神经松解术。
Pub Date : 2024-10-10 DOI: 10.1016/j.hansur.2024.101787
Thomas Apard

Radial nerve entrapment at the LIS is an aching pain in the distal, lateral upper arm and leads to weakness in wrist and thumb/index finger extension. Additionally, a positive scratch collapse test and localized pain on pressure at the entrapment site are observed. The described approach uses a minimally invasive percutaneous ultrasound-guided technique under local anesthesia.

LIS 处的桡神经卡压是上臂远端外侧的隐痛,并导致手腕和拇指/食指伸展无力。此外,还可观察到挠抓塌陷试验阳性和卡压部位局部疼痛。所述方法采用微创经皮超声引导技术,在局部麻醉下进行。
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引用次数: 0
Amyloidosis and carpal tunnel syndrome: can we predict occurrence? 淀粉样变性与腕管综合征:我们能预测发生率吗?
Pub Date : 2024-10-10 DOI: 10.1016/j.hansur.2024.101789
François Saade, Camille Barani, Matthieu Guyard, Matthieu Malatray, Élisabeth Hugon-Vallet, Philippe Schiele

Introduction: Carpal tunnel syndrome, especially when bilateral, may be associated with amyloid deposits, a precursor of systemic amyloidosis. Systemic amyloidosis affects various organs, cardiac involvement having the poorest prognosis. Diagnosis is often delayed. Current treatments are only effective in the early stages of the disease. The primary objective of our study was to evaluate the incidence of amyloidosis in patients with bilateral carpal tunnel syndrome; the secondary aim was to screen for cardiac forms.

Material and methods: Between 2019 and 2023, we conducted a single-center prospective observational and diagnostic study to investigate the anatomical pathology of amyloid deposits in tenosynovial samples taken during open nerve release surgery on the median nerve. The tenosynovial biopsy was sent to a specific laboratory for analysis, and typing if positive. If amyloidosis was detected, the patient was referred to a specialist for a specific work-up.

Results: We included 54 patients, with a mean age of 67 years (range, 51-89 years): 16 men and 38 women. Sixteen analyses were positive, 12 of which were transthyretin and 4 non-typed.

Discussion/conclusion: Bilateral carpal tunnel syndrome was predictive of amyloidosis. As synovial biopsy during surgery is simple and rapid, it should be implemented to identify amyloidosis at an early stage. This could change prognosis, by improving survival through screening and initiation of early specific treatment.

Level of evidence: IV.

导言腕管综合征,尤其是双侧腕管综合征,可能与淀粉样蛋白沉积有关,淀粉样蛋白沉积是全身性淀粉样变性的前兆。全身性淀粉样变性会影响多个器官,其中心脏受累的预后最差。诊断往往被延误。目前的治疗方法仅在疾病的早期阶段有效。我们研究的主要目的是评估双侧腕管综合征患者中淀粉样变性的发病率;次要目的是筛查心脏形式:2019年至2023年期间,我们开展了一项单中心前瞻性观察和诊断研究,调查在正中神经开放性神经松解手术中采集的腱鞘样本中淀粉样蛋白沉积的解剖病理。腱鞘活检样本被送往特定实验室进行分析,如果结果呈阳性,则进行分型。如果检测出淀粉样变性,患者将被转诊至专科医生进行具体检查:我们共纳入了 54 名患者,平均年龄为 67 岁(51-89 岁不等):其中男性 16 人,女性 38 人。16例分析结果呈阳性,其中12例为转甲状腺素,4例为非类型:讨论/结论:双侧腕管综合征可预测淀粉样变性。由于手术过程中的滑膜活检简单快捷,因此应在早期发现淀粉样变性。这可能会改变预后,通过筛查和早期特殊治疗提高存活率:证据等级:IV。
{"title":"Amyloidosis and carpal tunnel syndrome: can we predict occurrence?","authors":"François Saade, Camille Barani, Matthieu Guyard, Matthieu Malatray, Élisabeth Hugon-Vallet, Philippe Schiele","doi":"10.1016/j.hansur.2024.101789","DOIUrl":"10.1016/j.hansur.2024.101789","url":null,"abstract":"<p><strong>Introduction: </strong>Carpal tunnel syndrome, especially when bilateral, may be associated with amyloid deposits, a precursor of systemic amyloidosis. Systemic amyloidosis affects various organs, cardiac involvement having the poorest prognosis. Diagnosis is often delayed. Current treatments are only effective in the early stages of the disease. The primary objective of our study was to evaluate the incidence of amyloidosis in patients with bilateral carpal tunnel syndrome; the secondary aim was to screen for cardiac forms.</p><p><strong>Material and methods: </strong>Between 2019 and 2023, we conducted a single-center prospective observational and diagnostic study to investigate the anatomical pathology of amyloid deposits in tenosynovial samples taken during open nerve release surgery on the median nerve. The tenosynovial biopsy was sent to a specific laboratory for analysis, and typing if positive. If amyloidosis was detected, the patient was referred to a specialist for a specific work-up.</p><p><strong>Results: </strong>We included 54 patients, with a mean age of 67 years (range, 51-89 years): 16 men and 38 women. Sixteen analyses were positive, 12 of which were transthyretin and 4 non-typed.</p><p><strong>Discussion/conclusion: </strong>Bilateral carpal tunnel syndrome was predictive of amyloidosis. As synovial biopsy during surgery is simple and rapid, it should be implemented to identify amyloidosis at an early stage. This could change prognosis, by improving survival through screening and initiation of early specific treatment.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":94023,"journal":{"name":"Hand surgery & rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Hand surgery & rehabilitation
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