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Percutaneous cryoablation of renal tumours under computed tomography guidance: methodology of the procedure. 在计算机断层扫描指导下经皮肾肿瘤冷冻消融:手术方法学。
Pub Date : 2024-11-12 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/193205
Maciej Guziński, Wojciech Krajewski, Wojciech Tomczak, Łukasz Nowak, Jan Łaszkiewicz, Joanna Chorbińska, Adam Chełmoński, Bartosz Małkiewicz, Tomasz Szydełko

Purpose: The incidence of renal cell carcinoma has been steadily increasing over the past two decades, raising the need for minimally invasive approaches. We sought to present the methodology of the percutaneous cryoablation (PCA) procedure developed based on one year of experience with 81 PCA procedures.

Material and methods: The percutaneous cryoablation programme at Wroclaw Medical University Hospital has been successfully operating for a year. During this period, patients who were ineligible for partial nephrectomy either because of numerous comorbidities or strong preference against surgery were treated with PCA. Each procedure was conducted with the close cooperation of an interventional radiologist and a urologist.

Results: Over the past year, 81 procedures in 74 individuals have been performed and thoroughly analysed. The mean and median effective radiation doses were 12.57 mSv and 10.76 mSv, respectively. Comprehensive details of our workflow are described within the body of the manuscript.

Conclusions: Percutaneous cryoablation is a technically effective treatment approach for carefully selected individuals with small renal masses. However, starting a PCA programme from scratch necessitates creation of detailed protocols, as well as close interventional radiologist and urologist cooperation. This review outlines the established workflow and shares insights gained from one year of experience with percutaneous cryoablation.

目的:在过去的二十年中,肾细胞癌的发病率稳步上升,增加了对微创手术的需求。我们试图提出的方法经皮冷冻消融(PCA)程序开发基于一年的经验,81 PCA程序。材料和方法:弗罗茨瓦夫医科大学医院的经皮冷冻消融方案已成功实施一年。在此期间,由于许多合并症或强烈反对手术而不适合部分肾切除术的患者接受PCA治疗。每个手术都是在介入放射科医生和泌尿科医生的密切合作下进行的。结果:在过去的一年中,对74例患者进行了81例手术并进行了彻底分析。平均和中位有效辐射剂量分别为12.57毫西弗和10.76毫西弗。我们工作流程的全面细节在手稿的正文中描述。结论:经皮冷冻消融是一种技术上有效的治疗肾小肿块的方法。然而,从头开始PCA项目需要制定详细的方案,以及介入放射科医生和泌尿科医生的密切合作。这篇综述概述了已建立的工作流程,并分享了从一年的经皮冷冻消融经验中获得的见解。
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引用次数: 0
In response to the article "Comparison of posterior cranial fossa morphometric measurements in Chiari type I patients with and without syrinx cavity on magnetic resonance imaging". Pol J Radiol 2022; 87: e694-e700. 回应文章《有和无鸣管腔的Chiari I型患者后颅窝形态测量在磁共振成像上的比较》。Pol J Radiol 2022;87: e694-e700。
Pub Date : 2024-11-06 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/193073
Ertuğrul H Özay, Begumhan Baysal
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引用次数: 0
Added value of volumetric MRI pulse sequence 3D VISTA (Volume ISotopic Turbo spin echo Acquisition) in perianal fistula depiction and characterization. 体积MRI脉冲序列3D VISTA(体积同位素涡轮自旋回波采集)在肛周瘘描述和表征中的价值。
Pub Date : 2024-11-04 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/193232
Ahmed I Tawfik, Amir M Eltantawy, Mohamed Mohsen, Mohamed M Harraz

Purpose: Diagnosis of perianal fistula represents a challenge for surgeons. It is well known that magnetic resonance imaging (MRI) plays an important role in that. The new 3D MRI sequence VISTA (Volume ISotopic Turbo spin echo Acquisition) can improve detection and characterization of perianal fistula compared with two-dimensional (2D) sequences. The aim of the study was to compare the diagnostic performance of the new 3D MRI sequence VISTA with the widely routinely used T2 FSE pulse sequence in depiction and characterization of perianal fistula by using the contrast-enhanced (CE) 3D T1 sequence THRIVE (T1-weighted high-resolution isotropic volume examination) as a reference standard.

Material and methods: Forty adult patients were enrolled in this prospective study. They underwent MRI perianal region examination using routine T2 TSE and CE 3D T1 sequence THRIVE with addition of the new 3D MRI sequence VISTA. T2, 3D VISTA and (CE) 3D T1 sequence THRIVE images were evaluated by two radiologists separately for detection and characterization of perianal fistula, then comparison between of T2 and 3D VISTA sequences was done using (CE) 3D T1 sequence THRIVE as a reference. Each sequence sensitivity, specificity and accuracy were calculated by both readers.

Results: For reader 1, the sensitivity, specificity and accuracy were 92.5%, 90.5% and 93.6% for 3D VISTA and 84.1%, 83.7% and 87.3% for T2 FSE. For reader 2, the sensitivity, specificity and accuracy were 91.5%, 92.8% and 94.8% for 3D VISTA and 82.9%, 84.5% and 86.7% for T2 FSE.

Conclusions: Using CE 3D T1 sequence THRIVE as the reference standard, 3D VISTA pulse sequence on the perianal region has better diagnostic performance in the detection and characterization of perianal fistula as compared to the routinely used T2 FSE sequence.

目的:肛瘘的诊断对外科医生来说是一个挑战。众所周知,磁共振成像(MRI)在其中起着重要作用。与二维(2D)序列相比,新的三维MRI序列VISTA(体积同位素涡轮自旋回波采集)可以改善肛周瘘的检测和表征。本研究的目的是通过对比增强(CE) 3D T1序列THRIVE (T1加权高分辨率各向同性体积检查)作为参考标准,比较新的3D MRI序列VISTA与广泛常规使用的T2 FSE脉冲序列在描述和表征肛周瘘方面的诊断性能。材料和方法:40名成年患者被纳入这项前瞻性研究。他们接受了常规T2 TSE和CE 3D T1 THRIVE序列的MRI肛周检查,并添加了新的3D MRI序列VISTA。T2、3D VISTA和(CE) 3D T1序列THRIVE影像分别由两名放射科医师评估,用于检测和表征肛周瘘,然后以(CE) 3D T1序列THRIVE作为参考,比较T2和3D VISTA序列。每个序列的敏感性、特异性和准确性由两名读取器计算。结果:阅读器1对3D VISTA的敏感性、特异性和准确性分别为92.5%、90.5%和93.6%,对T2 FSE的敏感性、特异性和准确性分别为84.1%、83.7%和87.3%。阅读器2对3D VISTA的敏感性、特异性和准确性分别为91.5%、92.8%和94.8%,对T2 FSE的敏感性、特异性和准确性分别为82.9%、84.5%和86.7%。结论:以CE 3D T1序列THRIVE为参照标准,与常规使用T2 FSE序列相比,肛周区3D VISTA脉冲序列在检测和表征肛周瘘方面具有更好的诊断性能。
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引用次数: 0
Advancing radiology education for medical students: leveraging digital tools and resources. 推进医科学生的放射学教育:利用数字工具和资源。
Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/193518
Thomas Stirrat, Robert Martin, Muhammad Umair, Joseph Waller

This study evaluates diverse educational resources to address the gaps in diagnostic radiology education for medical students, aiming to identify tools that enhance theoretical knowledge and practical diagnostic skills. Employing a multi-faceted review, we analyzed digital platforms, academic databases, and social media for resources beneficial to medical students in radiology, assessing their accessibility, content quality, and educational value. Our investigation uncovered a broad spectrum of resources, from foundational platforms to advanced simulation tools, varying in their approach to teaching radiology. Traditional resources provide essential theoretical knowledge, while digital tools, including interactive case studies and multimedia content, offer immersive learning experiences. Notably, resources integrating machine learning and social media facilitate dynamic, peer-to-peer learning and up-to-date case discussions. Despite the minimal current focus on VR, its role in enhancing interactive learning is notable. The diversity in educational tools highlights the evolving nature of radiology education, reflecting a shift towards more engaging and practical learning methodologies. Identifying and integrating a variety of educational resources into radiology education can significantly enhance learning outcomes for medical students, preparing them for the complexities of modern diagnostic radiology with a well-rounded educational approach.

本研究评估了各种教育资源,以弥补医科学生在放射诊断学教育方面的不足,旨在找出能提高理论知识和实际诊断技能的工具。通过多方面的审查,我们分析了数字平台、学术数据库和社交媒体中对放射学医学生有益的资源,评估了它们的可访问性、内容质量和教育价值。我们的调查发现,从基础平台到高级模拟工具,各种资源的放射学教学方法各不相同。传统资源提供基本理论知识,而数字工具,包括互动案例研究和多媒体内容,则提供身临其境的学习体验。值得注意的是,整合了机器学习和社交媒体的资源促进了动态的点对点学习和最新的病例讨论。尽管目前对虚拟现实技术的关注极少,但它在增强互动学习方面的作用是显著的。教育工具的多样性凸显了放射学教育不断发展的本质,反映了向更具参与性和实用性学习方法的转变。将各种教育资源确定并整合到放射学教育中,可以显著提高医学生的学习成果,以全面的教育方法让他们为现代放射诊断学的复杂性做好准备。
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引用次数: 0
Application of ultrasound-guided intranodal lymphangiography in the diagnosis and treatment of chylous ascites after abdominal surgery. 超声引导下结节内淋巴管造影在诊断和治疗腹部手术后乳糜腹水中的应用。
Pub Date : 2024-10-18 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/193577
Juncheng Wan, Wen Zhang, Caihong Yu, Changyu Li, Yongjie Zhou, Wei Zhang, Zhuoyang Fan, Chaoqiao Jin, Xudong Qu

Purpose: Chylous leakage is a serious and challenging postoperative complication. The purpose of this study was to explore the application of ultrasound-guided intranodal lymphangiography in the diagnosis and treatment of chylous ascites following abdominal surgery.

Material and methods: Ten patients with chylous ascites after abdominal surgery after ineffective conservative treatment such as low-fat diet, parenteral nutrition, and negative pressure drainage were included in this single-center retrospective study. Of these 10 patients, 9 developed chylous ascites after liver surgery, and 1 after a radical gastrectomy.

Results: Lymphangiography was successfully performed in all 10 patients. The average dosage of lipiodol used was 4.5 ml (range 3.5-7.0 ml). No procedure-related complications were observed after excluding unrelated factors. During lymphangiography, lipiodol leakage was directly observed in 3 cases, and in the other 5 cases, it was detected through abdominal computed tomography post-lymphangiography. Chylous ascites resolved solely through lymphangiography in 6 patients without requiring additional surgical intervention.

Conclusions: Lymphangiography may help identify leakage sites in patients with chylous ascites unresponsive to conservative treatment and could potentially be effective in treating chylous ascites following abdominal surgery.

目的:乳糜腹水是一种严重且具有挑战性的术后并发症。本研究旨在探讨超声引导下结节内淋巴管造影在诊断和治疗腹部手术后乳糜腹水中的应用:这项单中心回顾性研究共纳入了 10 名腹部手术后出现乳糜腹水的患者,这些患者在接受低脂饮食、肠外营养和负压引流等保守治疗无效后出现了乳糜腹水。在这 10 名患者中,9 人在肝脏手术后出现了乳糜腹水,1 人在根治性胃切除术后出现了乳糜腹水:结果:10 名患者均成功实施了淋巴管造影术。脂肪碘醇的平均用量为 4.5 毫升(3.5-7.0 毫升不等)。排除无关因素后,未发现与手术相关的并发症。在淋巴管造影过程中,有 3 例患者直接观察到了脂肪碘的渗漏,另外 5 例患者则是在淋巴管造影后通过腹部计算机断层扫描发现的。6例患者的乳糜腹水仅通过淋巴管造影就得到了缓解,无需额外的手术干预:淋巴管造影可帮助确定保守治疗无效的乳糜腹水患者的渗漏部位,并有可能有效治疗腹部手术后的乳糜腹水。
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引用次数: 0
Medication-induced changes on magnetic resonance imaging of the brain. 药物引起的脑磁共振成像变化。
Pub Date : 2024-10-15 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/192463
Monika Bekiesinska-Figatowska, Barbara Bobek-Billewicz

In this review the authors focus on abnormal brain magnetic resonance imaging caused by drugs given to patients in any age group for any disease. The review includes viral infections with fever in children/infections in general, epilepsy, psychiatric diseases, multiple sclerosis, neoplasms, bone marrow/organ transplantations, total parenteral nutrition, vaccinations, oral contraceptives and other prothrombotic drugs, and gadolinium deposition. Knowledge of patients' diseases and medications they receive is crucial to establish the correct diagnosis. The absence of these data in a referral for a brain MRI scan can result in completely wrong suspicions and unleash unnecessary, complicated, time-consuming and expensive diagnostics, causing additional stress in patients and their guardians.

在这篇综述中,作者重点讨论了任何年龄组的患者因任何疾病服用药物而导致的脑磁共振成像异常。综述包括儿童发热病毒感染/一般感染、癫痫、精神疾病、多发性硬化、肿瘤、骨髓/器官移植、全肠外营养、疫苗接种、口服避孕药和其他促血栓形成药物以及钆沉积。了解患者的疾病和服用的药物对于确定正确的诊断至关重要。在转诊进行脑磁共振成像扫描时,如果缺乏这些数据,就可能导致完全错误的怀疑,并引发不必要、复杂、耗时和昂贵的诊断,给患者及其监护人带来额外的压力。
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引用次数: 0
The peritumoral brain zone in glioblastoma: a review of the pretreatment approach. 胶质母细胞瘤的瘤周脑区:预处理方法综述。
Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/192044
Anna Michalska-Foryszewska, Maciej Bujko, Agnieszka Kwiatkowska-Miernik, Katarzyna Ziemba, Katarzyna Sklinda, Jerzy Walecki, Bartosz Mruk

Glioblastomas are the most common and aggressive form of malignant primary brain tumors in adults. The standard treatment is surgical resection followed by radiotherapy and chemotherapy. Despite optimal treatment methods, the prognosis for patients remains poor. Preoperative determination of glioblastoma margins remains beneficial for the complete removal of the tumor mass. Radiotherapy is essential for post-surgery treatment, but radioresistance is a significant challenge contributing to high mortality rates. Advanced imaging technologies are used to analyze the changes in the peritumoral brain zone (PTZ). Consequently, they may lead to the development of novel therapeutic options, especially targeting the marginal parts of a tumor, which could improve the prognosis of glioblastoma patients. The clinical presentation of glioblastoma is heterogeneous and mostly depends on the location and size of a tumor. Glioblastomas are characterized by both intratumoral cellular heterogeneity and an extensive, diffuse infiltration into the normal tissue bordering a tumor called the PTZ. Neuroimaging techniques, such as diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), perfusion-weighted imaging (PWI), proton magnetic resonance spectroscopy (1H MRS), and chemical exchange saturation transfer (CEST) are useful methods in the evaluation of the tumor infiltration and thus the resection margin.

胶质母细胞瘤是成人恶性原发性脑肿瘤中最常见、最具侵袭性的一种。标准治疗方法是手术切除,然后进行放疗和化疗。尽管采用了最佳治疗方法,但患者的预后仍然很差。术前确定胶质母细胞瘤的边缘仍然有利于彻底切除肿瘤。放疗对术后治疗至关重要,但放射抗药性是导致高死亡率的一个重大挑战。先进的成像技术可用于分析瘤周脑区(PTZ)的变化。因此,这些技术可能会开发出新的治疗方案,尤其是针对肿瘤边缘部位的治疗方案,从而改善胶质母细胞瘤患者的预后。胶质母细胞瘤的临床表现多种多样,主要取决于肿瘤的位置和大小。胶质母细胞瘤的特点是瘤内细胞异质性和向肿瘤周围正常组织的广泛、弥漫性浸润(称为 PTZ)。神经成像技术,如弥散加权成像(DWI)、弥散张量成像(DTI)、灌注加权成像(PWI)、质子磁共振波谱(1H MRS)和化学交换饱和转移(CEST)是评估肿瘤浸润和切除边缘的有用方法。
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引用次数: 0
Comparative efficacy of contrast-enhanced ultrasound versus B-mode ultrasound in the diagnosis and monitoring of hepatic abscesses. 对比增强超声与 B 型超声在诊断和监测肝脓肿方面的功效。
Pub Date : 2024-10-08 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/192184
Adam Dobek, Mateusz Kobierecki, Wojciech Ciesielski, Oliwia Grząsiak, Konrad Kosztowny, Adam Fabisiak, Piotr Białek, Ludomir Stefańczyk

Purpose: This study aimed to evaluate the diagnostic value of contrast-enhanced ultrasound (CEUS) in diagnosing and monitoring hepatic abscesses (HA).

Material and methods: This retrospective study included 29 patients (9 females, 20 males) with 64 HA. Computed tomography (CT) served as the diagnostic benchmark, compared with CEUS and B-mode ultrasound (B-mode). Two radiologists assessed the presence, size, and characteristics of the HA.

Results: The contrast enhancement pattern on CEUS matched post-contrast CT. Lesion size detected by CEUS ranged from 1.16 cm to 15.33 cm (median 5.74 cm). CT classified lesions into four types: I (tumor-like) - 2, II (honeycomb) - 5, III (lacunar) - 23, IV (cystic-like) - 34. CEUS fully agreed with these classifications. B-mode missed two type I lesions. For type III abscesses, agreement with CEUS was perfect (κ = 1, 100%), and moderate with B-mode (κ = 0.50, 79.7%). For type IV abscesses, agreement with CEUS was perfect (κ = 1, 100%), and high with B-mode (κ = 0.88, 93.75%). Pus enhancement remained stable (± 15 dB), while the abscess pouch background varied (± 11 dB to ± 6 dB). The Mann-Whitney U test confirmed these observations (arterial: p = 1.02e-14, portal: p = 3.79e-12, late venous: p = 4.53e-13). No significant difference in enhancement values was found based on abscess size (> 4 cm vs. < 4 cm).

Conclusions: CEUS is superior to B-mode for diagnosing and monitoring HA, offering clearer views of the abscess pouch, septa, and liver parenchyma. The purulent part lacks contrast, allowing accurate assessment. CEUS can replace CT for monitoring and aid in patient selection for percutaneous intervention.

目的:本研究旨在评估对比增强超声(CEUS)在诊断和监测肝脓肿(HA)方面的诊断价值:这项回顾性研究纳入了 29 名患者(9 名女性,20 名男性),共 64 例肝脓肿。计算机断层扫描(CT)作为诊断基准,与 CEUS 和 B 型超声波(B 型)进行比较。两名放射科医生对 HA 的存在、大小和特征进行了评估:结果:CEUS的对比增强模式与对比后CT相匹配。CEUS检测到的病变大小从1.16厘米到15.33厘米不等(中位数为5.74厘米)。CT 将病变分为四种类型:I(肿瘤样)- 2,II(蜂窝状)- 5,III(裂隙状)- 23,IV(囊肿样)- 34。CEUS 与这些分类完全一致。B 超漏诊了两个 I 型病变。对于 III 型脓肿,CEUS 与之完全吻合(κ = 1,100%),B-mode 与之中度吻合(κ = 0.50,79.7%)。对于 IV 型脓肿,与 CEUS 的一致性非常好(κ = 1,100%),与 B 型的一致性较高(κ = 0.88,93.75%)。脓液增强保持稳定(± 15 dB),而脓袋背景则有变化(± 11 dB 到 ± 6 dB)。Mann-Whitney U 检验证实了这些观察结果(动脉:p = 1.02e-14;门静脉:p = 3.79e-12;晚期静脉:p = 4.53e-13)。脓肿大小(> 4 cm 与 < 4 cm)对增强值无明显差异:结论:CEUS在诊断和监测HA方面优于B型超声波,能更清晰地观察脓肿袋、隔膜和肝实质。化脓部分缺乏造影剂,可进行准确评估。CEUS 可替代 CT 进行监测,并有助于选择经皮介入治疗的患者。
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引用次数: 0
Assessment of thyroid nodule risk stratification knowledge and utilization among Polish physicians: a pilot study. 波兰医生对甲状腺结节风险分层知识和利用情况的评估:一项试点研究。
Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/193414
Lukasz Janicki, Agastya Patel, Tomasz Nowicki, Andrzej Hellmann

Purpose: Ultrasonography is the primary diagnostic tool for evaluating thyroid nodules. The Thyroid Imaging Reporting & Data System (TIRADS) aims to standardise assessment and reduce fine-needle aspiration biopsies through risk stratification. This pilot study examined knowledge and utilisation of TIRADS among Polish physicians, their perception of the usefulness of TIRADS application and the extent of knowledge of individual nodule features included.

Material and methods: An internet-based questionnaire about TIRADS use in clinical practice was sent out to Polish Ultrasound Society members. Information on the responder's experience with thyroid ultrasound and knowledge and use of TIRADS was assessed and analysed.

Results: Out of 159 physicians, 66.6% did not use TIRADS despite 43.4% being aware of its existence. EU-TIRADS was the most commonly adopted classification (50.9%). Participants who adopted TIRADS were younger (p = 0.047) and more likely to be radiologists (p < 0.01). TIRADS use was more prevalent in university clinical hospitals (p = 0.02), among physicians doing thyroid ultrasound as their primary professional activity (p < 0.01), those performing > 100 thyroid ultrasound examinations per year (p < 0.01) and those involved with thyroid fine-needle aspiration biopsy (p < 0.01). The purposes of TIRADS adoption (p < 0.01) and included imaging features (p < 0.01) were more accurately recognized by TIRADS users.

Conclusions: TIRADS utilization among Polish clinicians is limited, despite awareness of the classification's existence. Knowledge of TIRADS components and the purpose of its application among users is satisfactory. Further training and TIRADS adoption should be encouraged, especially in the light of the recent EU-TIRADS-PL guidelines recommended by the Polish Scientific Societies.

目的:超声波检查是评估甲状腺结节的主要诊断工具。甲状腺成像报告和数据系统(TIRADS)旨在通过风险分层实现评估标准化并减少细针穿刺活检。这项试点研究调查了波兰医生对 TIRADS 的了解和使用情况、他们对 TIRADS 应用的实用性的看法以及对个别结节特征的了解程度:向波兰超声协会会员发送了一份关于临床实践中使用 TIRADS 的网络问卷。结果:在 159 名医生中,66% 的人使用了 TIRADS:结果:在 159 名医生中,尽管有 43.4% 的人知道 TIRADS 的存在,但仍有 66.6% 的人没有使用过 TIRADS。欧盟-TIRADS是最常采用的分类方法(50.9%)。采用 TIRADS 的参与者更年轻(p = 0.047),更有可能是放射科医生(p < 0.01)。TIRADS在大学临床医院(p = 0.02)、以甲状腺超声为主要职业的医生(p < 0.01)、每年进行甲状腺超声检查超过100次的医生(p < 0.01)以及参与甲状腺细针穿刺活检的医生(p < 0.01)中使用更为普遍。TIRADS用户对采用TIRADS的目的(p < 0.01)和包含的成像特征(p < 0.01)的识别更为准确:结论:波兰临床医生对 TIRADS 的使用有限,尽管他们知道该分类的存在。用户对 TIRADS 组成部分及其应用目的的了解程度令人满意。应鼓励进一步培训和采用 TIRADS,特别是考虑到波兰科学协会最近推荐的欧盟-TIRADS-PL 指南。
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引用次数: 0
Computed tomography features in prediction of histological differentiation of pancreatic neuroendocrine neoplasms - a single-centre retrospective cohort study. 预测胰腺神经内分泌肿瘤组织学分化的计算机断层扫描特征--一项单中心回顾性队列研究。
Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.5114/pjr/191838
Jan Krzysztof Herzyk, Karolina Majewska, Krzysztof Jakimów, Jakub Ciesielka, Joanna Pilch-Kowalczyk

Purpose: The aim of our study was to analyse the histological differentiation and computed tomography imaging features of pancreatic neuroendocrine neoplasms (PNENs).

Material and methods: We performed a retrospective single-centre cohort study of 157 patients with histologically confirmed PNEN. We compared the results of the preoperative biopsy from the tumour with reports of the multi-slice computed tomography performed by a radiologist with 30 years of clinical practice.

Results: Specific computed tomography (CT) features are associated with histological differentiation, such as enhancement in the arterial phase (p = 0.032), Wirsung's duct dilatation (p = 0.001), other organ infiltration (p < 0.001), distant metastases (p < 0.001), and enlarged regional lymph nodes (p = 0.018). When there is an organ infiltration, the likelihood of the tumour having histological malignancy grades G2 or G3 triples (95% CI: 1.21-8.06). Likewise, the existence of distant metastases increases the risk almost fourfold (95% CI: 1.44-10.61), and a tumour size of 2 cm or larger is linked to a nearly threefold rise in the risk of histological malignancy grades G2 or G3 (95% CI: 1.21-6.24).

Conclusions: Certain CT characteristics: enhancement during the arterial phase, Wirsung's duct dilatation, organ infiltration, distant metastases, and the enlargement of regional lymph nodes are linked to histological differentiation.

目的:我们的研究旨在分析胰腺神经内分泌肿瘤(PNEN)的组织学分化和计算机断层扫描成像特征:我们对157名组织学确诊的胰腺神经内分泌瘤患者进行了一项回顾性单中心队列研究。我们将肿瘤术前活检结果与一位有 30 年临床经验的放射科医生所做的多层计算机断层扫描报告进行了比较:结果:特定的计算机断层扫描(CT)特征与组织学分化有关,如动脉期增强(p = 0.032)、维尔兴氏管扩张(p = 0.001)、其他器官浸润(p < 0.001)、远处转移(p < 0.001)和区域淋巴结肿大(p = 0.018)。当出现器官浸润时,肿瘤组织学恶性程度达到 G2 或 G3 级的可能性增加三倍(95% CI:1.21-8.06)。同样,存在远处转移也会使风险增加近四倍(95% CI:1.44-10.61),肿瘤大小为 2 厘米或更大与组织学恶性程度 G2 或 G3 级的风险增加近三倍(95% CI:1.21-6.24)有关:结论:某些 CT 特征:动脉期增强、维尔兴氏管扩张、器官浸润、远处转移和区域淋巴结肿大与组织学分化有关。
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Polish journal of radiology
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