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Barriers and facilitators to implementation of proper limb positioning in hemiplegic stroke patients: a qualitative study. 偏瘫脑卒中患者实施正确肢体定位的障碍和促进因素:一项定性研究。
Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0110en
Xin-Yue Zhang, Min-Min Leng, Jia-Wei Yang, Shuo-Tao Li, Min Li, Xiao-Xu Ji, Quan-Qin Cui, Fang Liang, Xia Chen, Li-Juan Yang

Objective: To identify factors that can be targeted to promote the standardized management of proper limb positioning and improve the rehabilitation outcomes of patient.

Method: A qualitative descriptive study was conducted using semi-structured face-to-face in-depth interviews with 24 clinical nurses working in stroke-related departments between April and May 2024. Based on the COM-B model, the data were analyzed by employing the deductive content analysis method using the NVivo12 software and manual coding.

Results: Analysis revealed 11 themes and 22 sub-themes associated with the four domains of the COM-B model, including 15 barriers and 7 facilitators.

Conclusion: Clinical nurses' adherence to proper limb positioning is dynamic and positioning should address barriers related to capability, opportunity, and motivation, such as prioritize knowledge and skills training for clinical nurses, improved compliance among patients and caregivers, establish robust systems and supervisory mechanisms, and support scientific research and innovation to explore intelligent management solutions.

目的:探讨有针对性的影响因素,促进正确肢体定位规范化管理,提高患者康复效果。方法:采用半结构化面对面深度访谈的方法,对2024年4 - 5月在脑卒中相关科室工作的24名临床护士进行定性描述性研究。基于COM-B模型,利用NVivo12软件和人工编码,采用演绎内容分析法对数据进行分析。结果:在COM-B模型的4个领域中,共发现了11个主题和22个子主题,包括15个障碍和7个促进因素。结论:临床护士;坚持正确的肢体定位是动态的,定位应解决与能力、机会和动机相关的障碍,如优先考虑临床护士的知识和技能培训,提高患者和护理人员的依从性,建立健全的系统和监督机制,支持科学研究和创新,探索智能管理解决方案。
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引用次数: 0
Experience of heart failure patients in mobilization with virtual reality: mixed methods study. 心衰患者虚拟现实动员的经验:混合方法研究。
Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0114en
Larissa Gussatschenko Caballero, Iasmin Borges Fraga, Carlos Eduardo Maciel Tremea, Gabrielle Perin, Janaína Dos Santos Prates, Pedro Dal Lago, João Lucas Campos de Oliveira, Eneida Rejane Rabelo-Silva

Objective: To compare the effects of up to three sessions of an early mobilization protocol combined with immersive virtual reality (VR) versus early mobilization alone in the experience of patients with acutely decompensated heart failure.

Methods: Complex mixed methods study with adult patients admitted to the intensive care unit. The Intervention Group (IG) underwent mobilization combined with immersive virtual reality and the Control Group (CG), isolated mobilization. The tool Net Promoter Score (NPS) and the Likert scale were used to assess patients' experience. In the qualitative approach, interviews were conducted with open questions.

Results: Sixty patients participated in the study, 44 (73.3%) men, mean age 59.7 ± 12.2. The procedure was recommended by 23 (76.7%) in the IG and by 24 (80%) in the CG. The mobilization experience was classified as good or excellent by 28 (93.3%) in the IG and 26 (83.7%) in the CG. Qualitative analyses revealed three categories: "Psychological Effects", "Physical Performance" and "Innovation".

Conclusion: Combining virtual reality with early mobilization provided a more positive experience for patients. ClinicalTrials.gov with number NCT05596292.

目的:比较三次联合沉浸式虚拟现实(VR)的早期活动方案与单独的早期活动对急性失代偿性心力衰竭患者的影响。方法:采用复杂混合方法对重症监护病房的成年患者进行研究。干预组(IG)采用沉浸式虚拟现实联合动员,对照组(CG)采用孤立动员。使用净推荐值(NPS)和李克特量表来评估患者的体验。在定性方法中,访谈以开放式问题进行。结果:60例患者参与研究,男性44例(73.3%),平均年龄59.7±12.2岁。IG组有23例(76.7%)推荐,CG组有24例(80%)推荐。IG组有28人(93.3%)评价为良好或优秀,CG组有26人(83.7%)评价为良好或优秀。定性分析揭示了三个类别:“心理影响”、“身体表现”和“创新”。结论:将虚拟现实与早期活动相结合,为患者提供了更积极的体验。ClinicalTrials.gov,编号NCT05596292。
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引用次数: 0
Effect of nursing interventions on the rehabilitation of patients after knee and hip replacements. 护理干预对膝关节和髋关节置换术后患者康复的影响。
Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0184en
Qing Sheng, Guangling Wang, Pengfei Wang

Objective: This systematic review and meta-analysis aimed to assess the effect of nursing interventions, considering their importance in the rehabilitation of patients undergoing knee and hip replacement.

Methods: Three databases were systematically searched. Two researchers carefully reviewed the full texts of the selected studies and extracted the required data. Further, a meta-analysis was conducted.

Results: Of the 19 studies reviewed, 17 revealed that nursing interventions can improve the rehabilitation of patients after knee and hip replacement operations. Among patients with hip replacements, the results indicated that nursing interventions can significantly increase the Harris hip score and activities of daily living compared with usual care. Among patients with knee replacements, the results revealed that nursing interventions can significantly improve range of motion and knee function and reduce knee pain compared with usual care.

Conclusions: Evidence reveals that individualized care and evidence-based strategies combined with various exercises and training provided by a multidisciplinary team significantly influence the physical rehabilitation among patients undergoing knee and hip replacement.

目的:本系统回顾和荟萃分析旨在评估护理干预的效果,考虑其在膝关节和髋关节置换术患者康复中的重要性。方法:系统检索三个数据库。两位研究人员仔细审查了所选研究的全文,并提取了所需的数据。进一步进行meta分析。结果:在回顾的19项研究中,17项研究显示护理干预可以改善膝关节和髋关节置换术后患者的康复。在髋关节置换术患者中,结果表明,护理干预与常规护理相比,可显著提高Harris髋关节评分和日常生活活动能力。在膝关节置换术患者中,结果显示,与常规护理相比,护理干预可以显著改善患者的活动范围和膝关节功能,减轻膝关节疼痛。结论:有证据表明,个性化护理和循证策略结合多学科团队提供的各种运动和训练对膝关节和髋关节置换术患者的身体康复有显著影响。
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引用次数: 0
Information on latent tuberculosis infection in higher education: social representations of nursing students. 高等院校护生潜伏性肺结核感染信息:社会表征。
Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0029en
Erlon Gabriel Rego de Andrade, Ivaneide Leal Ataíde Rodrigues, Laura Maria Vidal Nogueira, Eliza Paixão da Silva, Adriely Alciany Miranda Dos Santos, Letícia Gabriela Noronha Rodrigues, Débora de Cássia Quaresma Silva, Vitória de Cássia Quaresma Silva

Objective: To analyze the social representations of nursing students regarding the sharing of information about latent tuberculosis infection in higher education.

Method: Descriptive, qualitative study, anchored in the procedural aspect of the Theory of Social Representations. It was carried out with 37 students who reacted to the tuberculin test, enrolled from the 1st to the 5th grade, in the Undergraduate Nursing Course at a public university in Belém, Pará, Brazil. Between March and July 2023, semi-structured individual interviews were conducted, the corpus of which was subjected to lexical analysis with the software Interface de R pour les Analyses Multidimensionnelles de Textes et de Questionnaires (0.7, alpha 2), using descending hierarchical classification.

Results: A total of 1,939 text segments were identified, of which 1,686 (86.95%) were used, generating seven lexical classes. It was decided to detail class 7, which outlined two representational sets, addressing how information was shared and suggestions on the topic.

Conclusion: The limitations that weakened the timely sharing and quality of information motivated students to make suggestions to solve the challenges inherent to this context or mitigate its harmful effects.

目的:分析护生对高等院校潜伏性结核感染信息共享的社会表征。方法:描述性定性研究,以社会表征理论的程序方面为基础。该研究是在37名对结核菌素测试有反应的学生中进行的,这些学生从一年级到五年级,就读于巴西帕尔贝尔萨姆一所公立大学的本科护理课程。在2023年3月至7月间,进行了半结构化的个人访谈,使用Interface de R pour les Analyses Multidimensionnelles de Textes et de questionnaire (0.7, alpha 2)软件对语料库进行词法分析,采用降序分层分类。结果:共识别出1939个文本片段,其中使用了1686个(86.95%),生成了7个词汇类。决定详细介绍第7课,它概述了两个代表性集,讨论如何共享信息和关于该主题的建议。结论:削弱信息及时共享和质量的限制促使学生提出建议,以解决这种情况下固有的挑战或减轻其有害影响。
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引用次数: 0
Factors relating to climate change anxiety in women at reproductive age: A CHAID analysis. 育龄妇女气候变化焦虑相关因素:CHAID分析
Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0182en
Tuğçe Sönmez, Enes Karaman

Objective: This study aimed to determine the factors relating to climate change anxiety in women at reproductive age.

Method: This study is descriptive and cross-sectional. This study included 351 women aged 18-45 years. Data were collected via face to face interviews using the 'Women's Descriptive Characteristics and Climate Change Perception Assessment Form' and 'Climate Change Anxiety Scale for Women's Health' between June and October 2024 at a family health center in Mersin province of Türkiye. Data analysis included descriptive statistical methods and chi-squared automatic ınteraction detector analysis.

Results: The average age of the women was 27.91 ± 8.30 years (n = 351). The Climate Change Anxiety Scale for Women's Health mean score was 52.46 ± 17.19. Women's experience of anxiety regarding the negative consequences of climate change affected the scale and all sub-dimensions (physiological health, behavior, and gender) (p < 0.05).

Conclusion: Health professionals should provide information and assessments including the effects of climate change on health in care services. They should plan interventions to reduce women's anxiety levels towards climate change.

目的:本研究旨在确定育龄妇女气候变化焦虑的相关因素。方法:本研究采用描述性和横断面法。这项研究包括351名年龄在18-45岁之间的女性。研究人员于2024年6月至10月在德国梅尔辛省的一家家庭健康中心使用“妇女描述性特征和气候变化感知评估表”和“妇女健康气候变化焦虑量表”进行面对面访谈,收集数据。数据分析包括描述性统计方法和卡方自动ınteraction检测器分析。结果:女性平均年龄为27.91±8.30岁(n = 351)。妇女健康气候变化焦虑量表平均得分为52.46±17.19分。妇女对气候变化负面后果的焦虑体验影响了量表和所有子维度(生理健康、行为和性别)(p < 0.05)。结论:卫生专业人员应提供信息和评估,包括气候变化对卫生保健服务的影响。他们应该计划干预措施,以减少妇女对气候变化的焦虑程度。
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引用次数: 0
Impact of an educational intervention on postpartum depression for primary care nurses: a quasi-experimental study. 教育干预对初级保健护士产后抑郁的影响:一项准实验研究。
Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0032en
Débora Alves da Silva, Marli Aparecida Reis Coimbra, Lucas Carvalho Santana, Maria Aline Leocádio, Fernanda Bonato Zuffi, Lúcia Aparecida Ferreira

Objective: To evaluate the impact of an educational intervention on nursing care for women with signs of postpartum depression for primary health care nurses.

Method: Quasi-experimental, before-and-after study carried out with 14 primary health care nurses from a municipality, who participated in an educational intervention on nursing care for women with signs of postpartum depression. Qualitative data analysis was carried out before and after the intervention, using Bardin's thematic content analysis.

Results: From the comparison of the content responses before and after the intervention, the nurses presented more knowledge about postpartum depression, especially in specific signs and symptoms, and improvement in the recognition and management of baby blues; they began using scales for screening and better monitoring of emotional symptoms; they began adopting more humanized practices, in addition to reporting greater safety in care and multidisciplinary integration.

Conclusion: The intervention had a positive impact and expanded nurses' knowledge, skills, and attitudes regarding postpartum depression, which contributed to more empathetic and comprehensive care. ReBEC: RBR-3hv3hhs.

目的:评价教育干预对初级卫生保健护士产后抑郁症状护理的影响。方法:对14名参加产后抑郁症状妇女护理教育干预的市级基层卫生保健护士进行准实验前后研究。采用Bardin主题内容分析法,在干预前后进行定性数据分析。结果:从干预前后的内容反应对比来看,护理人员对产后抑郁症的认识有所提高,特别是对产后抑郁症的具体体征和症状的认识有所提高,对产后抑郁症的认识和管理有所改善;他们开始使用量表来筛选和更好地监测情绪症状;他们开始采用更人性化的做法,除了报告更安全的护理和多学科整合。结论:干预具有积极的影响,扩展了护士对产后抑郁症的知识、技能和态度,有助于提高护理的同理心和综合性。三弦琴:RBR-3hv3hhs。
{"title":"Impact of an educational intervention on postpartum depression for primary care nurses: a quasi-experimental study.","authors":"Débora Alves da Silva, Marli Aparecida Reis Coimbra, Lucas Carvalho Santana, Maria Aline Leocádio, Fernanda Bonato Zuffi, Lúcia Aparecida Ferreira","doi":"10.1590/1980-220X-REEUSP-2025-0032en","DOIUrl":"10.1590/1980-220X-REEUSP-2025-0032en","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of an educational intervention on nursing care for women with signs of postpartum depression for primary health care nurses.</p><p><strong>Method: </strong>Quasi-experimental, before-and-after study carried out with 14 primary health care nurses from a municipality, who participated in an educational intervention on nursing care for women with signs of postpartum depression. Qualitative data analysis was carried out before and after the intervention, using Bardin's thematic content analysis.</p><p><strong>Results: </strong>From the comparison of the content responses before and after the intervention, the nurses presented more knowledge about postpartum depression, especially in specific signs and symptoms, and improvement in the recognition and management of baby blues; they began using scales for screening and better monitoring of emotional symptoms; they began adopting more humanized practices, in addition to reporting greater safety in care and multidisciplinary integration.</p><p><strong>Conclusion: </strong>The intervention had a positive impact and expanded nurses' knowledge, skills, and attitudes regarding postpartum depression, which contributed to more empathetic and comprehensive care. ReBEC: RBR-3hv3hhs.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":"59 ","pages":"e20250032"},"PeriodicalIF":0.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145025034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interprofessional collaboration in Primary Health Care: preceptors and professors in Education Program for Health Work. 初级卫生保健的跨专业合作:卫生工作教育计划的教师和教授。
Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2024-0206en
Elaine Andrade Leal Silva, Rosana Maria de Oliveira Silva, Ana Lúcia Arcanjo Oliveira Cordeiro, Queuam Ferreira Silva de Oliveira, Rafaela Braga Pereira Velôso, Gilberto Tadeu Reis da Silva

Objective: This article aims to analyze the performance of professors and preceptors of the Education Program for Health Work in the development of interprofessional collaboration in Primary Health Care.

Method: Descriptive study, with a qualitative approach, in which professors and preceptors from the Education Program for Health Work of five federal universities in the Brazilian Northeast participated. Between September and October 2020, 44 workers responded to the online questionnaire. Data were processed according to analytical procedures described by Bardin and interpreted in light of the four-dimensional Model of Interprofessional Collaboration with the aid of webQDA® software.

Results: Three categories were identified: 1) Provision for sharing common goals; 2) Mobilization for internalization of interdependence between professionals, and 3) Monitoring and adjustment for the development of interprofessional collaboration.

Conclusion: The study revealed that the role of professors and preceptors in developing interprofessional collaboration is significantly focused on the interactive conduct between health professionals and students, as well as on the development of actions and adjustments for collaborative work.

目的:本文旨在分析卫生工作教育计划的教授和辅导员在发展初级卫生保健专业间合作中的表现。方法:采用定性方法进行描述性研究,由巴西东北部五所联邦大学卫生工作教育项目的教授和辅导员参与。在2020年9月至10月期间,44名工人回答了在线问卷。根据Bardin描述的分析程序处理数据,并借助webQDA®软件根据跨专业协作的四维模型进行解释。结果:确定了三类:1)提供共享共同目标;2)动员专业人员之间相互依存的内部化;3)监测和调整专业间合作的发展。结论:本研究显示,教授和导师在发展跨专业协作中的作用主要集中在卫生专业人员与学生之间的互动行为,以及协作工作的行动和调整的发展。
{"title":"Interprofessional collaboration in Primary Health Care: preceptors and professors in Education Program for Health Work.","authors":"Elaine Andrade Leal Silva, Rosana Maria de Oliveira Silva, Ana Lúcia Arcanjo Oliveira Cordeiro, Queuam Ferreira Silva de Oliveira, Rafaela Braga Pereira Velôso, Gilberto Tadeu Reis da Silva","doi":"10.1590/1980-220X-REEUSP-2024-0206en","DOIUrl":"10.1590/1980-220X-REEUSP-2024-0206en","url":null,"abstract":"<p><strong>Objective: </strong>This article aims to analyze the performance of professors and preceptors of the Education Program for Health Work in the development of interprofessional collaboration in Primary Health Care.</p><p><strong>Method: </strong>Descriptive study, with a qualitative approach, in which professors and preceptors from the Education Program for Health Work of five federal universities in the Brazilian Northeast participated. Between September and October 2020, 44 workers responded to the online questionnaire. Data were processed according to analytical procedures described by Bardin and interpreted in light of the four-dimensional Model of Interprofessional Collaboration with the aid of webQDA® software.</p><p><strong>Results: </strong>Three categories were identified: 1) Provision for sharing common goals; 2) Mobilization for internalization of interdependence between professionals, and 3) Monitoring and adjustment for the development of interprofessional collaboration.</p><p><strong>Conclusion: </strong>The study revealed that the role of professors and preceptors in developing interprofessional collaboration is significantly focused on the interactive conduct between health professionals and students, as well as on the development of actions and adjustments for collaborative work.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":"59 ","pages":"e20240206"},"PeriodicalIF":0.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nursing care in primary health care to tackle antimicrobial resistance in pregnant women with urinary tract infections. 在初级卫生保健中处理尿路感染孕妇抗微生物药物耐药性的护理。
Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0001en
Jamile Leite de Figueiredo, Maria Clara Padoveze

Objective: To identify pregnant women with urinary tract infections who are being monitored at a primary health care unit and their knowledge about antibiotics, as well as facilitating and challenging factors perceived by nurses that influence care, with a focus on antimicrobial resistance.

Method: Exploratory, descriptive study with a quantitative approach, involving pregnant women with urinary tract infections undergoing antibiotic treatment at a municipal health unit in São Paulo and nurses working at the same location. Data were obtained from computerized systems, medical records, and interviews, and were synthesized and analyzed using Microsoft Excel and Stata software.

Results: Of the 21 pregnant women included, 85.7% had knowledge about antibiotics. Of the 11 participating nurses, 36.4% did not identify the presence of facilitators, but 45.5% believed there were barriers to their care.

Final considerations: Most pregnant women had basic knowledge about antibiotics and recognized the importance of guidance from nurses. Nurses identified barriers that point to the need for technical support. Developing a care booklet for nurses who care for pregnant women with urinary tract infections may be a promising strategy to optimize treatment and prevent antimicrobial resistance.

目的:确定在初级卫生保健单位监测的尿路感染孕妇及其抗生素知识,以及护士认为影响护理的促进和挑战因素,重点是抗菌素耐药性。方法:探索性描述性研究,采用定量方法,涉及在圣保罗市卫生单位接受抗生素治疗的尿路感染孕妇和在同一地点工作的护士。数据来自计算机系统、医疗记录和访谈,并使用Microsoft Excel和Stata软件进行综合和分析。结果:纳入的21例孕妇中,85.7%的人对抗生素知识有所了解。在11名参与调查的护士中,36.4%的人不知道助理员的存在,但45.5%的人认为他们的护理存在障碍。最后考虑因素:大多数孕妇对抗生素有基本的了解,并认识到护士指导的重要性。护士们确定了需要技术支持的障碍。为护理尿路感染孕妇的护士编写护理手册可能是优化治疗和预防抗菌素耐药性的一种有前途的策略。
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引用次数: 0
Effects of intravenous laser irradiation on viral load and T lymphocytes in people living with HIV/AIDS. 静脉激光照射对HIV/AIDS感染者病毒载量和T淋巴细胞的影响。
Pub Date : 2025-09-05 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0004en
Fabiana Tomé Ramos, Maria Cecília Yoshioka Lobo, Hélio Amante Miot, Eliana Maria Minicucci, Rúbia Aguiar Alencar

Objective: To evaluate the effectiveness of intravenous laser irradiation of blood in reducing viral load and increasing LT-CD4+ and LT-CD8+ in people living with HIV/AIDS.

Method: Randomized, controlled, parallel, single-blind clinical trial. Twenty-eight participants were allocated to the intervention (ILIB n = 15) and control (CTRL n = 13) groups. The ILIB group received irradiation with red laser (660 nm), applied to the radial artery (30 minutes/day for 20 days), with a total energy of 180 J. The CTRL group received a sham intervention (without light emission). Viral load and LT-CD4+ and LT-CD8+ counts were assessed at the end.

Results: Both groups showed a reduction in viral load (ILIB: -1.7 log; CTRL: -2.3 log). In the ILIB group, 61.5% of participants achieved an undetectable viral load (p = 0.449). There was no increase in CD4+ LT count (p = 0.287), but a non-significant reduction in CD8+ LT count was observed in the ILIB group (p = 0.173). There were no statistically significant differences between groups for any outcome (p > 0.17). The study was stopped prematurely during the interim analysis.

Conclusion: ILIB, as an adjuvant therapy to ART, did not show clinical or statistical superiority in the immunological and virological parameters evaluated.

Brazilian registry of clinical trials (rebec): RBR-7j9rv5d (https://ensaiosclinicos.gov.br/trial/10848).

目的:探讨静脉激光照射血液在降低HIV/AIDS感染者病毒载量、提高LT-CD4+和LT-CD8+水平中的作用。方法:随机、对照、平行、单盲临床试验。28名参与者被分配到干预组(ILIB n = 15)和对照组(CTRL n = 13)。ILIB组采用红色激光(660 nm)照射桡动脉(30分钟/天,持续20天),总能量180 j。CTRL组采用假干预(无光发射)。最后评估病毒载量、LT-CD4+和LT-CD8+计数。结果:两组均显示病毒载量降低(ILIB: -1.7 log; CTRL: -2.3 log)。在ILIB组中,61.5%的参与者达到了无法检测到的病毒载量(p = 0.449)。CD4+ LT计数无升高(p = 0.287),而CD8+ LT计数在ILIB组无显著降低(p = 0.173)。两组间任何结果均无统计学差异(p < 0.17)。该研究在中期分析期间过早停止。结论:ILIB作为ART的辅助疗法,在免疫学和病毒学指标评价上没有表现出临床或统计学上的优势。巴西临床试验登记处(rebec): RBR-7j9rv5d (https://ensaiosclinicos.gov.br/trial/10848)。
{"title":"Effects of intravenous laser irradiation on viral load and T lymphocytes in people living with HIV/AIDS.","authors":"Fabiana Tomé Ramos, Maria Cecília Yoshioka Lobo, Hélio Amante Miot, Eliana Maria Minicucci, Rúbia Aguiar Alencar","doi":"10.1590/1980-220X-REEUSP-2025-0004en","DOIUrl":"10.1590/1980-220X-REEUSP-2025-0004en","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of intravenous laser irradiation of blood in reducing viral load and increasing LT-CD4+ and LT-CD8+ in people living with HIV/AIDS.</p><p><strong>Method: </strong>Randomized, controlled, parallel, single-blind clinical trial. Twenty-eight participants were allocated to the intervention (ILIB n = 15) and control (CTRL n = 13) groups. The ILIB group received irradiation with red laser (660 nm), applied to the radial artery (30 minutes/day for 20 days), with a total energy of 180 J. The CTRL group received a sham intervention (without light emission). Viral load and LT-CD4+ and LT-CD8+ counts were assessed at the end.</p><p><strong>Results: </strong>Both groups showed a reduction in viral load (ILIB: -1.7 log; CTRL: -2.3 log). In the ILIB group, 61.5% of participants achieved an undetectable viral load (p = 0.449). There was no increase in CD4+ LT count (p = 0.287), but a non-significant reduction in CD8+ LT count was observed in the ILIB group (p = 0.173). There were no statistically significant differences between groups for any outcome (p > 0.17). The study was stopped prematurely during the interim analysis.</p><p><strong>Conclusion: </strong>ILIB, as an adjuvant therapy to ART, did not show clinical or statistical superiority in the immunological and virological parameters evaluated.</p><p><strong>Brazilian registry of clinical trials (rebec): </strong>RBR-7j9rv5d (https://ensaiosclinicos.gov.br/trial/10848).</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":"59 ","pages":"e20250004"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive capacity of trauma indices for hospitalization and intensive care unit admission. 创伤指数对住院和重症监护病房入院的预测能力。
Pub Date : 2025-09-05 eCollection Date: 2025-01-01 DOI: 10.1590/1980-220X-REEUSP-2025-0092en
Lillian Caroline Fernandes, Daniel Bueno Damasceno, Fernanda Naves de Oliveira Lima, Lilia de Souza Nogueira, Ramon Antonio Oliveira, Filipe Utuari de Andrade Coelho, Regina Marcia Cardoso de Sousa

Objective: To compare the performance of trauma severity indices (ISS, NISS, REMS, mREMS) in predicting hospital and Intensive Care Unit (ICU) admission outcomes.

Method: Retrospective cohort study carried out with patients treated at the Emergency Room of a private hospital from January 2020 to January 2022. Medical records of adults with blunt, penetrating, or mixed trauma admitted up to 24 hours after the trauma were analyzed. Severity indices were used to predict hospital and ICU admission.

Results: The sample consisted of 151 patients. The ISS and NISS showed good discrimination capacity for hospital and ICU admission (AUC/ROC from 0.84 to 0.85). The REMS and mREMS indices showed insufficient performance (AUC/ROC from 0.62 to 0.67).

Conclusion: The ISS and NISS indices were effective in predicting hospital and ICU admission and can be used in clinical practice; however, the use of REMS and mREMS cannot be recommended due to insufficient performance for these outcomes.

目的:比较创伤严重程度指数(ISS、NISS、REMS、mREMS)对医院和重症监护病房(ICU)住院预后的预测效果。方法:对2020年1月至2022年1月在某私立医院急诊室就诊的患者进行回顾性队列研究。对创伤后24小时内收治的钝性、穿透性或混合性创伤的成人医疗记录进行了分析。严重程度指标用于预测住院和ICU住院情况。结果:样本共151例。ISS和NISS对住院和ICU住院具有良好的区分能力(AUC/ROC为0.84 ~ 0.85)。REMS和mREMS指标表现不佳(AUC/ROC为0.62 ~ 0.67)。结论:ISS和NISS指标可有效预测住院和ICU住院情况,可用于临床;然而,由于这些结果的性能不足,不推荐使用REMS和mREMS。
{"title":"Predictive capacity of trauma indices for hospitalization and intensive care unit admission.","authors":"Lillian Caroline Fernandes, Daniel Bueno Damasceno, Fernanda Naves de Oliveira Lima, Lilia de Souza Nogueira, Ramon Antonio Oliveira, Filipe Utuari de Andrade Coelho, Regina Marcia Cardoso de Sousa","doi":"10.1590/1980-220X-REEUSP-2025-0092en","DOIUrl":"10.1590/1980-220X-REEUSP-2025-0092en","url":null,"abstract":"<p><strong>Objective: </strong>To compare the performance of trauma severity indices (ISS, NISS, REMS, mREMS) in predicting hospital and Intensive Care Unit (ICU) admission outcomes.</p><p><strong>Method: </strong>Retrospective cohort study carried out with patients treated at the Emergency Room of a private hospital from January 2020 to January 2022. Medical records of adults with blunt, penetrating, or mixed trauma admitted up to 24 hours after the trauma were analyzed. Severity indices were used to predict hospital and ICU admission.</p><p><strong>Results: </strong>The sample consisted of 151 patients. The ISS and NISS showed good discrimination capacity for hospital and ICU admission (AUC/ROC from 0.84 to 0.85). The REMS and mREMS indices showed insufficient performance (AUC/ROC from 0.62 to 0.67).</p><p><strong>Conclusion: </strong>The ISS and NISS indices were effective in predicting hospital and ICU admission and can be used in clinical practice; however, the use of REMS and mREMS cannot be recommended due to insufficient performance for these outcomes.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":"59 ","pages":"e20250092"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Revista da Escola de Enfermagem da U S P
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