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Nursing care for women with HELLP syndrome: a scoping review. 为患有 HELLP 综合征的妇女提供护理:范围界定综述。
Pub Date : 2024-08-12 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2024-0116en
Pâmela Silva Arduini, Cynthya Viana de Resende, Jéssica Aparecida da Silva, Mariana Torreglosa Ruiz

Objective: To map evidence on nursing care for women with HELLP syndrome.

Method: A scoping review with searches carried out in May 2023, independently, in the PubMed/MEDLINE, LILACS, Scopus, EMBASE, Web of Science, CINAHL, CAPES Theses and Dissertations Catalog and Cochrane Library databases, correlating the descriptors HELLP Syndrome, Nursing Care and Obstetric Nursing and its synonyms, without delimitation of time and language. Selection was carried out by three researchers independently and resolved by consensus.

Results: Of the 129 studies, ten were selected, which made up the final sample. The studies date from 2004 to 2022, with a predominance of English language and clinical case studies. A greater occurrence of the syndrome was observed in second-time pregnant women in the second decade of life, with a gestational age from 32 weeks, which resulted in an emergency cesarean section, and all newborns were discharged accompanied by their mothers. Studies that described nursing diagnoses and focused on nursing care were retrieved. From the review, 39 nursing care were identified.

Conclusion: This review pointed out the magnitude of the syndrome, however with a lack of studies.

目的绘制针对 HELLP 综合征妇女的护理证据图:方法:2023 年 5 月,在 PubMed/MEDLINE、LILACS、Scopus、EMBASE、Web of Science、CINAHL、CAPES 论文目录和 Cochrane 图书馆数据库中,以 HELLP 综合征、护理和产科护理及其同义词为关键词,进行独立检索,不限定时间和语言。筛选工作由三名研究人员独立完成,并以协商一致的方式解决:结果:在 129 项研究中,有 10 项被选中,成为最终样本。这些研究的时间跨度为 2004 年至 2022 年,以英语和临床病例研究为主。据观察,该综合征更多发生在第二个十年的二胎孕妇身上,胎龄从 32 周起,导致紧急剖宫产,所有新生儿都在母亲的陪伴下出院。研究检索了描述护理诊断和关注护理的研究。综述中确定了 39 项护理:本综述指出了该综合征的严重性,但缺乏相关研究。
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引用次数: 0
Analysis of intensive care unit admissions for older adults with femoral fractures: a retrospective cohort. 股骨骨折老年人入住重症监护室情况分析:回顾性队列。
Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2023-0398en
Carolina Rodrigues Mendes Nogueira Cobra, Paulo Carlos Garcia, Isadora Castilho Moreira de Oliveira Passos, Greiciane da Silva Rocha, Lilia de Souza Nogueira

Objectives: To describe the historical series of admissions to the Intensive Care Unit of older adults with femoral fractures, and verify the association between age and injury characteristics and treatment, nursing workload, severity, and clinical evolution in the unit.

Method: Retrospective cohort of 295 older adults (age ≥60 years) admitted to the Intensive Care Unit of a hospital in São Paulo, between 2013 and 2019, and who presented with a femur fracture as the main cause of hospitalization. Variables regarding demographic characteristics, cause, and type of fracture, treatment provided, severity, nursing workload, and medical outcome of patients were analyzed. The Shapiro-Wilk, Wilcoxon-Mann-Whitney, Kruskal-Wallis tests and Pearson correlation were applied.

Results: There was an increase in older adults admission to the Intensive Care Unit from 2017 on. Female patients with distal femur fractures who died in the Intensive Care Unit had significantly (p < 0.05) higher median age than men, patients with shaft or proximal femur fractures, and survivors.

Conclusion: The study findings highlight essential information for structuring care for older adults with femoral fractures who require intensive care.

目的描述股骨骨折老年人入住重症监护室的历史序列,并验证年龄、损伤特征与治疗、护理工作量、严重程度以及重症监护室临床演变之间的关联:方法:对2013年至2019年期间在圣保罗一家医院重症监护室住院的295名老年人(年龄≥60岁)进行回顾性队列,他们住院的主要原因是股骨骨折。研究分析了患者的人口统计学特征、骨折原因和类型、所提供的治疗、严重程度、护理工作量和医疗结果等变量。采用了 Shapiro-Wilk、Wilcoxon-Mann-Whitney、Kruskal-Wallis 检验和 Pearson 相关性检验:从2017年起,入住重症监护室的老年人有所增加。在重症监护室死亡的股骨远端骨折女性患者的中位年龄明显高于男性、股骨轴或近端骨折患者以及幸存者(P<0.05):研究结果强调了为需要重症监护的股骨骨折老年人提供护理的基本信息。
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引用次数: 0
Alcohol use as a predictor of child-to-parent violence in adolescents from southern Mexico. 酗酒是墨西哥南部青少年遭受儿童对父母暴力的预测因素。
Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2024-0016en
Pedro Moisés Noh-Moo, Lubia Del Carmen Castillo-Arcos, Juan Yovani Telumbre-Terrero, Lucely Maas-Góngora, Sylvia Claudine Ramírez-Sánchez, Roberto Joel Tirado-Reyes

Objective: To analyze the relationship and effect of alcohol use on Child-to-Parent Violence (CPV).

Method: Cross-sectional, observational study with a quantitative approach, carried out through online data collection using the Conflict Tactics Scale (CTS2) and the Alcohol Use Disorders Identification Test (AUDIT) in 318 high school adolescents from southern Mexico.

Results: Moderate and significant relationships were found between alcohol use and verbal (rs = 0.408, p = 0.001) and economic violence against the mother (rs = 0.445, p = 0.001). A similar situation is presented in physical (rs = 0.473, p = 0.001), verbal (rs = 0.236, p = 0.001) and economic (rs = 0.477, p = 0.001) violence directed to the father.

Conclusion: The relation among the variables was supported by Multiple Linear Regression models, with alcohol consumption in adolescents being a predictor of violence against mothers and fathers.

目的:分析饮酒与儿童对父母暴力(CPV)的关系和影响:分析饮酒与儿童对父母暴力(CPV)的关系和影响:采用定量方法,通过在线数据收集,使用冲突策略量表(CTS2)和酒精使用障碍识别测试(AUDIT)对墨西哥南部的 318 名高中青少年进行横断面观察研究:结果发现,酗酒与针对母亲的言语暴力(rs = 0.408,p = 0.001)和经济暴力(rs = 0.445,p = 0.001)之间存在明显的中度关系。针对父亲的身体暴力(rs = 0.473,p = 0.001)、语言暴力(rs = 0.236,p = 0.001)和经济暴力(rs = 0.477,p = 0.001)也呈现出类似的情况:多元线性回归模型证实了变量之间的关系,即青少年饮酒量可预测对母亲和父亲的暴力行为。
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引用次数: 0
Skin injuries in newborns hospitalized in neonatal intensive care: a cross-sectional study. 新生儿重症监护室住院新生儿的皮肤损伤:一项横断面研究。
Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2024-0058en
Carolina Tenfen, Grasiely Masotti Scalabrin Barreto, Neide Martins Moreira, Helder Ferreira, Adriana Zilly, Rosane Meire Munhak da Silva

Objective: To analyze the skin injuries of hospitalized newborns and identify factors related to the number of lesions.

Method: This was a cross-sectional epidemiological study carried out over a period of one year in a Neonatal Intensive Care Unit in the west of Paraná. The study included 74 newborns with a score ≥5 on the Newborn Skin Condition Scale. Data analysis by chi-square and Pearson's test (p < 0.05).

Results: The frequency was 25.4%, 59.4% had more than one lesion, mainly dermatitis and pressure injury. Birth characteristics were not related to the number of lesions. Not using antibiotics and parenteral nutrition, hemoglobin >11g/dl, phototherapy, pain score <4 and hospitalization >30 days were related to the number of lesions. The presence of two injuries led to longer healing time and three to longer hospitalization. A higher score on the Skin Condition Scale was related to healing time and late start of the diet.

Conclusion: Skin injuries were found to be infrequent among newborns, but there is still a need to improve practices to prevent and maintain skin integrity.

摘要分析住院新生儿的皮肤损伤情况,并确定与损伤数量有关的因素:这是一项横断面流行病学研究,在巴拉那州西部的一家新生儿重症监护室进行,为期一年。研究对象包括新生儿皮肤状况量表得分≥5 分的 74 名新生儿。数据分析采用卡方检验和皮尔逊检验(P < 0.05):结果:新生儿皮肤状况量表得分≥5分的新生儿占总数的25.4%,59.4%的新生儿有一种以上的皮肤损伤,主要是皮炎和压迫性损伤。出生特征与皮损数量无关。未使用抗生素和肠外营养、血红蛋白大于 11g/dl、光疗、30 天疼痛评分与皮损数量有关。有两处损伤会延长愈合时间,有三处损伤会延长住院时间。皮肤状况量表得分越高,痊愈时间越长,饮食开始得越晚:结论:皮肤损伤在新生儿中并不常见,但仍需改进预防和保持皮肤完整性的方法。
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引用次数: 0
Tracheostomy care for adults and the elderly in the home environment: a scoping review. 家庭环境中的成人和老年人气管造口护理:范围界定综述。
Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2024-0028en
Aldenora Laísa Paiva de Carvalho Cordeiro, Jade Alycia Ribeiro E Santos, Ana Clara Leite Barroso, Miguir Terezinha Vieccelli Donoso, Luciana Regina Ferreira Pereira da Mata, Tânia Couto Machado Chianca

Objective: To map out scientific knowledge regarding tracheostomy care for adults and the elderly carried out by individuals, famies or caregivers in home environments.

Method: Scoping review, conducted in February 2023, according to the methodology of the Joanna Briggs Institute. The guiding question was: what and how should adult/elderly tracheostomy care be carried out by the individual/family/caregiver in the home environment? Studies published in Portuguese, English and Spanish were considered. The databases consulted were: Lilacs; Medline, via PubMed; Cinahl; Cochrane Library; PEDro; Embase; Scopus and Web of Science.

Results: 2158 articles were identified, of which 81 were read in full and 14 included in the review. The main types of care identified included psychobiological needs: airway suction, changing the tracheostomy attachment, cleaning the endocannula and sanitizing the peristomal skin. As for psychosocial needs, incentives for communication and autonomy were identified. There were no recommendations for care related to psychospiritual needs.

Conclusion: The findings prioritize biological care, few studies have detailed how to carry out such care at home.

目的了解有关个人、家庭或护理人员在家庭环境中对成人和老年人进行气管造口术护理的科学知识:根据乔安娜-布里格斯研究所(Joanna Briggs Institute)的方法,于 2023 年 2 月进行了范围综述。指导性问题是:在家庭环境中,个人/家庭/护理人员应如何进行成人/老年人气管造口护理?研究考虑了以葡萄牙语、英语和西班牙语发表的研究。查阅的数据库有结果:共发现 2158 篇文章,对其中 81 篇进行了全文阅读,14 篇被纳入综述。确定的主要护理类型包括心理生物学需求:气道吸引、更换气管造口附件、清洁内腔和肛周皮肤消毒。在社会心理需求方面,确定了鼓励交流和自主的措施。结论:研究结果将生物护理放在首位,但很少有研究详细说明如何在家中进行此类护理。
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引用次数: 0
Association between cortisol levels and performance in clinical simulation: a systematic review. 皮质醇水平与临床模拟成绩之间的关系:系统综述。
Pub Date : 2024-07-26 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2023-0279en
Jackson Gois Teixeira, Lucas Tomaz Benigno Lima, Elaine Carvalho Cunha, Flavia Oliveira de Almeida Marques da Cruz, Karen Karoline Gouveia Carneiro, Laiane Medeiros Ribeiro, Guilherme da Costa Brasil

Objective: To identify how stress measured by salivary cortisol during clinical simulation-based education, or simulation and another teaching method, impacts performance.

Method: Systematic review of the association between cortisol and performance in simulations. The following databases were used: PubMed, LIVIVO, Scopus, EMBASE, Latin American and Caribbean Health Sciences Literature (LILACS) and Web of Science. Additional searches of gray literature were carried out on Google Scholar and Proquest. The searches took place on March 20, 2023. The risk of bias of randomized clinical trials was assessed using the Cochrane Collaboration Risk of Bias Tool (RoB 2). Inclusion criteria were: simulation studies with salivary cortisol collection and performance evaluation, published in any period in Portuguese, English and Spanish.

Results: 11 studies were included which measured stress using salivary cortisol and were analyzed using descriptive synthesis and qualitative analysis.

Conclusion: Some studies have shown a relationship between stress and performance, which may be beneficial or harmful to the participant. However, other studies did not show this correlation, which may not have been due to methodological issues.

目的确定在基于临床模拟的教学过程中,或在模拟和另一种教学方法中,通过唾液皮质醇测量的压力如何影响成绩:方法:系统回顾模拟教学中皮质醇与成绩之间的关系。使用了以下数据库:PubMed、LIVIVO、Scopus、EMBASE、Latin American and Caribbean Health Sciences Literature (LILACS) 和 Web of Science。此外,还在 Google Scholar 和 Proquest 上对灰色文献进行了搜索。搜索时间为 2023 年 3 月 20 日。随机临床试验的偏倚风险采用 Cochrane 协作偏倚风险工具 (RoB 2) 进行评估。纳入标准为:在任何时期以葡萄牙语、英语和西班牙语发表的带有唾液皮质醇收集和性能评估的模拟研究:结果:纳入了 11 项使用唾液皮质醇测量压力的研究,并使用描述性综合分析和定性分析进行了分析:结论:一些研究表明,压力与成绩之间存在关系,这可能对参与者有利,也可能有害。然而,其他研究并没有显示出这种相关性,这可能不是因为方法问题。
{"title":"Association between cortisol levels and performance in clinical simulation: a systematic review.","authors":"Jackson Gois Teixeira, Lucas Tomaz Benigno Lima, Elaine Carvalho Cunha, Flavia Oliveira de Almeida Marques da Cruz, Karen Karoline Gouveia Carneiro, Laiane Medeiros Ribeiro, Guilherme da Costa Brasil","doi":"10.1590/1980-220X-REEUSP-2023-0279en","DOIUrl":"10.1590/1980-220X-REEUSP-2023-0279en","url":null,"abstract":"<p><strong>Objective: </strong>To identify how stress measured by salivary cortisol during clinical simulation-based education, or simulation and another teaching method, impacts performance.</p><p><strong>Method: </strong>Systematic review of the association between cortisol and performance in simulations. The following databases were used: PubMed, LIVIVO, Scopus, EMBASE, Latin American and Caribbean Health Sciences Literature (LILACS) and Web of Science. Additional searches of gray literature were carried out on Google Scholar and Proquest. The searches took place on March 20, 2023. The risk of bias of randomized clinical trials was assessed using the Cochrane Collaboration Risk of Bias Tool (RoB 2). Inclusion criteria were: simulation studies with salivary cortisol collection and performance evaluation, published in any period in Portuguese, English and Spanish.</p><p><strong>Results: </strong>11 studies were included which measured stress using salivary cortisol and were analyzed using descriptive synthesis and qualitative analysis.</p><p><strong>Conclusion: </strong>Some studies have shown a relationship between stress and performance, which may be beneficial or harmful to the participant. However, other studies did not show this correlation, which may not have been due to methodological issues.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11277686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141763638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical effect and prognostic factor of electric stimulation and biofeedback therapy on postpartum pelvic organ prolapse. 电刺激和生物反馈疗法对产后盆腔器官脱垂的临床效果和预后因素。
Pub Date : 2024-07-19 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2023-0421en
Hongjin Wu, Xiaoying Zhong, Linqian He, Xixi Li, Yan Zeng, Yuanli Jia

Objective: To explore the effects of electric stimulation and biofeedback therapy in patients with postpartum pelvic organ prolapse and to identify factors that can affect therapeutic efficacy outcomes.

Method: This retrospective study analysed clinical data about patients with postpartum pelvic organ prolapse. A total of 328 women with pelvic organ prolapse at 6 weeks postpartum were recruited from one tertiary hospitals in Sichuan province in China, between March 2019 and March 2022. The prognostic factors of therapeutic efficacy were analysed using logistic regression and decision tree model.

Results: Overall, 259 women showed clinical benefits from the treatment. The logistic regression model showed that parity, pelvic floor muscle training at home, and the pelvic organ prolapse quantitation stage before treatment were independent prognostic factors. The decision tree model showed that the pelvic organ prolapse quantitation stage before treatment was the main prognostic factor, followed by parity. There was no significant difference in the area under the receiver operating characteristic curve between the two models.

Conclusion: Parity, pelvic floor muscle training at home, and the pelvic organ prolapse quantitation stage before treatment were important prognostic factors of electric stimulation and biofeedback therapy on postpartum pelvic organ prolapse.

目的探讨电刺激和生物反馈疗法对产后盆腔器官脱垂患者的影响,并找出影响疗效的因素:这项回顾性研究分析了产后盆腔器官脱垂患者的临床数据。在2019年3月至2022年3月期间,从中国四川省的一家三甲医院共招募了328名产后6周的盆腔器官脱垂妇女。采用逻辑回归和决策树模型分析疗效的预后因素:结果:总体而言,259 名妇女从治疗中获得了临床益处。逻辑回归模型显示,奇偶数、在家进行的盆底肌肉训练和治疗前的盆腔器官脱垂量化分期是独立的预后因素。决策树模型显示,治疗前的盆腔器官脱垂量化阶段是主要的预后因素,其次是奇偶性。两种模型的接收者操作特征曲线下面积无明显差异:结论:胎次、在家进行的盆底肌肉训练和治疗前的盆腔器官脱垂量化阶段是电刺激和生物反馈疗法治疗产后盆腔器官脱垂的重要预后因素。
{"title":"Clinical effect and prognostic factor of electric stimulation and biofeedback therapy on postpartum pelvic organ prolapse.","authors":"Hongjin Wu, Xiaoying Zhong, Linqian He, Xixi Li, Yan Zeng, Yuanli Jia","doi":"10.1590/1980-220X-REEUSP-2023-0421en","DOIUrl":"10.1590/1980-220X-REEUSP-2023-0421en","url":null,"abstract":"<p><strong>Objective: </strong>To explore the effects of electric stimulation and biofeedback therapy in patients with postpartum pelvic organ prolapse and to identify factors that can affect therapeutic efficacy outcomes.</p><p><strong>Method: </strong>This retrospective study analysed clinical data about patients with postpartum pelvic organ prolapse. A total of 328 women with pelvic organ prolapse at 6 weeks postpartum were recruited from one tertiary hospitals in Sichuan province in China, between March 2019 and March 2022. The prognostic factors of therapeutic efficacy were analysed using logistic regression and decision tree model.</p><p><strong>Results: </strong>Overall, 259 women showed clinical benefits from the treatment. The logistic regression model showed that parity, pelvic floor muscle training at home, and the pelvic organ prolapse quantitation stage before treatment were independent prognostic factors. The decision tree model showed that the pelvic organ prolapse quantitation stage before treatment was the main prognostic factor, followed by parity. There was no significant difference in the area under the receiver operating characteristic curve between the two models.</p><p><strong>Conclusion: </strong>Parity, pelvic floor muscle training at home, and the pelvic organ prolapse quantitation stage before treatment were important prognostic factors of electric stimulation and biofeedback therapy on postpartum pelvic organ prolapse.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11308478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141904072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological screening for congenital toxoplasmosis in newborns from Jataí, Goiás, Brazil: a cross-sectional study. 巴西戈亚斯州雅塔伊市新生儿先天性弓形虫生物筛查:一项横断面研究。
Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2023-0408en
Gabriela Katrinny Avelar Oliveira, Stéfanne Rodrigues Rezende Ferreira, Vanessa Oliveira Lopes de Moura, Victor da Silva Siqueira, Thaís Santos Anjo Reis, Vanessa Bridi, Ludimila Paula Vaz Cardoso, Hanstter Hallison Alves Rezende

Objective: To conduct a serological screening for toxoplasmosis in the heel prick test and to evaluate its epidemiological aspects in newborns and postpartum women in Jataí, Goiás.

Method: Cross-sectional epidemiological study for the biological screening of newborns in Jataí, Goiás.

Results: The study participants amounted to 228 newborns, whose samples were collected between the third and seventh day of life. IgG antibodies against Toxoplasma gondii were detected in 40.79% (93/228) of the samples; out of these, 23.6% (22/93) had high IgG antibody titers, leading to the collection of two other peripheral blood samples and the detection of a decrease in these titers.

Conclusion: The findings show the importance of strengthening actions in primary health care to prevent infection and training health professionals in this area to equip them with information regarding cases of reinfection and reactivation of infection in pregnant women, minimizing risks for babies.

目的通过足跟点刺试验对弓形虫进行血清学筛查,并对戈亚斯州雅塔伊市新生儿和产后妇女的弓形虫流行病学方面进行评估:方法:对戈亚斯州雅塔伊市的新生儿进行生物学筛查的横断面流行病学研究:参与研究的 228 名新生儿的样本是在出生后第三天至第七天采集的。在 40.79%(93/228)的样本中检测到了弓形虫 IgG 抗体;其中 23.6%(22/93)的样本 IgG 抗体滴度较高,因此采集了另外两个外周血样本,并检测到滴度有所下降:研究结果表明,必须加强初级卫生保健中预防感染的行动,并对该领域的卫生专业人员进行培训,使他们掌握有关孕妇再感染和感染再活化病例的信息,从而最大限度地降低婴儿面临的风险。
{"title":"Biological screening for congenital toxoplasmosis in newborns from Jataí, Goiás, Brazil: a cross-sectional study.","authors":"Gabriela Katrinny Avelar Oliveira, Stéfanne Rodrigues Rezende Ferreira, Vanessa Oliveira Lopes de Moura, Victor da Silva Siqueira, Thaís Santos Anjo Reis, Vanessa Bridi, Ludimila Paula Vaz Cardoso, Hanstter Hallison Alves Rezende","doi":"10.1590/1980-220X-REEUSP-2023-0408en","DOIUrl":"10.1590/1980-220X-REEUSP-2023-0408en","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a serological screening for toxoplasmosis in the heel prick test and to evaluate its epidemiological aspects in newborns and postpartum women in Jataí, Goiás.</p><p><strong>Method: </strong>Cross-sectional epidemiological study for the biological screening of newborns in Jataí, Goiás.</p><p><strong>Results: </strong>The study participants amounted to 228 newborns, whose samples were collected between the third and seventh day of life. IgG antibodies against Toxoplasma gondii were detected in 40.79% (93/228) of the samples; out of these, 23.6% (22/93) had high IgG antibody titers, leading to the collection of two other peripheral blood samples and the detection of a decrease in these titers.</p><p><strong>Conclusion: </strong>The findings show the importance of strengthening actions in primary health care to prevent infection and training health professionals in this area to equip them with information regarding cases of reinfection and reactivation of infection in pregnant women, minimizing risks for babies.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adherence to standard precautions in university hospitals during the COVID-19 pandemic: a mixed study. COVID-19 大流行期间大学医院对标准预防措施的遵守情况:一项混合研究。
Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2023-0289en
Quézia Boeira da Cunha, Etiane de Oliveira Freitas, Daiane Dal Pai, José Luís Guedes Dos Santos, Rosângela Marion da Silva, Silviamar Camponogara

Objective: To analyze adherence to standard precautions by healthcare professionals and associated factors during the COVID-19 pandemic in Brazilian university hospitals.

Method: Multicenter study, with a mixed approach, with a concomitant incorporated strategy and a sample of 559 health professionals and 53 managers from five university hospitals in Southern Brazil. Data collected online from September 2020 to October 2021 with the Instrument of Variables Related to Standard Precautions and sociodemographic and pandemic-related variables. Descriptive and inferential statistical analysis (Mann-Whitney and Kruskal-Wallis test) and content analysis were performed.

Results: High level of adherence to standard precautions, with a significant association with having children (p = 0.014); COVID area (p < 0.001), biosafety training (p = 0.018), and social distancing (p < 0.001). The testimonies demonstrated a high risk perception and search for the use of protective equipment and biosafety knowledge.

Conclusion: High adherence to standard precautions, associated with having children, working in COVID-19 care units, receiving biosafety guidance/training at the institution and practicing social distancing.

目的分析巴西大学医院医护人员在 COVID-19 大流行期间遵守标准预防措施的情况及相关因素:多中心研究,采用混合方法,同时采用合并策略,样本包括巴西南部五所大学医院的 559 名医护人员和 53 名管理人员。从 2020 年 9 月至 2021 年 10 月,利用标准预防措施相关变量工具以及社会人口和大流行相关变量在线收集数据。进行了描述性和推论性统计分析(Mann-Whitney 和 Kruskal-Wallis 检验)以及内容分析:对标准预防措施的遵守程度较高,与有子女(p = 0.014)、COVID 地区(p < 0.001)、生物安全培训(p = 0.018)和社会距离(p < 0.001)有显著关联。这些证词表明,人们对风险的认知度很高,并希望使用防护设备和了解生物安全知识:结论:高度遵守标准预防措施与有子女、在 COVID-19 护理单位工作、在机构接受生物安全指导/培训以及保持社会距离有关。
{"title":"Adherence to standard precautions in university hospitals during the COVID-19 pandemic: a mixed study.","authors":"Quézia Boeira da Cunha, Etiane de Oliveira Freitas, Daiane Dal Pai, José Luís Guedes Dos Santos, Rosângela Marion da Silva, Silviamar Camponogara","doi":"10.1590/1980-220X-REEUSP-2023-0289en","DOIUrl":"10.1590/1980-220X-REEUSP-2023-0289en","url":null,"abstract":"<p><strong>Objective: </strong>To analyze adherence to standard precautions by healthcare professionals and associated factors during the COVID-19 pandemic in Brazilian university hospitals.</p><p><strong>Method: </strong>Multicenter study, with a mixed approach, with a concomitant incorporated strategy and a sample of 559 health professionals and 53 managers from five university hospitals in Southern Brazil. Data collected online from September 2020 to October 2021 with the Instrument of Variables Related to Standard Precautions and sociodemographic and pandemic-related variables. Descriptive and inferential statistical analysis (Mann-Whitney and Kruskal-Wallis test) and content analysis were performed.</p><p><strong>Results: </strong>High level of adherence to standard precautions, with a significant association with having children (p = 0.014); COVID area (p < 0.001), biosafety training (p = 0.018), and social distancing (p < 0.001). The testimonies demonstrated a high risk perception and search for the use of protective equipment and biosafety knowledge.</p><p><strong>Conclusion: </strong>High adherence to standard precautions, associated with having children, working in COVID-19 care units, receiving biosafety guidance/training at the institution and practicing social distancing.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gentiopicroside injection promotes the healing of pressure injury wounds by upregulating the expression of bFGFR1. 龙胆草甙注射液通过上调 bFGFR1 的表达促进压力损伤伤口的愈合。
Pub Date : 2024-07-08 eCollection Date: 2024-01-01 DOI: 10.1590/1980-220X-REEUSP-2023-0183en
Qiang Li, Xiaoshuan Liu, Min Zhang, Jungang Liu, Juan Lu

Objective: To observe the therapeutic effect of gentiopicroside, as the main component of Gentianaceae, on wounds in pressure injury (PI) model rats and explore its mechanism.

Method: Male Sprague Dawley rats were randomly divided into control group, model group and gentiopicroside groups (50, 100 and 200 mg·kg-1·d-1 for 9 consecutive days). The mice's skeletal muscle fibroblast line NOR-10 cells were collected after being treated with gentiopicroside (0.2~5.0 M) and basic fibroblast growth factor receptor 1 (bFGFR1) inhibitor (5.0 M SU5402) for 7 days.

Results: Compared to the model group, the gentiopicroside groups showed significantly increased wound healing rates, reduced inflammatory cells in the wound tissues, and significantly increased expression levels of proliferating cell nuclear antigen (PCNA) and bFGFR1, accompanied by increased proliferation of new myofibroblasts. Gentiopicroside upregulated the mRNA expression of bFGFR1 and PCNA in NOR-10 cells in a dose-dependent manner; however, SU5402 reversed the effect of gentiopicroside.

Conclusion: Gentiopicroside may promote myofibroblast proliferation by upregulating the expression of bFGFR1 and PCNA and ultimately accelerating the healing of PI wounds.

目的观察龙胆草甙(龙胆草科植物龙胆草的主要成分)对压伤(PI)模型大鼠伤口的治疗作用,并探讨其作用机制:将雄性 Sprague Dawley 大鼠随机分为对照组、模型组和龙胆草甙组(50、100 和 200 mg-kg-1-d-1,连续 9 天)。用龙胆草甙(0.2~5.0 M)和碱性成纤维细胞生长因子受体 1(bFGFR1)抑制剂(5.0 M SU5402)处理小鼠骨骼肌成纤维细胞系 NOR-10 细胞 7 天后收集细胞:结果:与模型组相比,龙胆草甙组的伤口愈合率明显提高,伤口组织中的炎症细胞减少,增殖细胞核抗原(PCNA)和碱性成纤维细胞生长因子受体1(bFGFR1)的表达水平明显提高,同时新生肌成纤维细胞的增殖增加。龙胆草甙能以剂量依赖的方式上调 NOR-10 细胞中 bFGFR1 和 PCNA 的 mRNA 表达,但 SU5402 能逆转龙胆草甙的作用:结论:龙胆草甙可通过上调表皮生长因子受体1(bFGFR1)和PCNA的表达促进肌成纤维细胞的增殖,并最终加速PI伤口的愈合。
{"title":"Gentiopicroside injection promotes the healing of pressure injury wounds by upregulating the expression of bFGFR1.","authors":"Qiang Li, Xiaoshuan Liu, Min Zhang, Jungang Liu, Juan Lu","doi":"10.1590/1980-220X-REEUSP-2023-0183en","DOIUrl":"10.1590/1980-220X-REEUSP-2023-0183en","url":null,"abstract":"<p><strong>Objective: </strong>To observe the therapeutic effect of gentiopicroside, as the main component of Gentianaceae, on wounds in pressure injury (PI) model rats and explore its mechanism.</p><p><strong>Method: </strong>Male Sprague Dawley rats were randomly divided into control group, model group and gentiopicroside groups (50, 100 and 200 mg·kg-1·d-1 for 9 consecutive days). The mice's skeletal muscle fibroblast line NOR-10 cells were collected after being treated with gentiopicroside (0.2~5.0 M) and basic fibroblast growth factor receptor 1 (bFGFR1) inhibitor (5.0 M SU5402) for 7 days.</p><p><strong>Results: </strong>Compared to the model group, the gentiopicroside groups showed significantly increased wound healing rates, reduced inflammatory cells in the wound tissues, and significantly increased expression levels of proliferating cell nuclear antigen (PCNA) and bFGFR1, accompanied by increased proliferation of new myofibroblasts. Gentiopicroside upregulated the mRNA expression of bFGFR1 and PCNA in NOR-10 cells in a dose-dependent manner; however, SU5402 reversed the effect of gentiopicroside.</p><p><strong>Conclusion: </strong>Gentiopicroside may promote myofibroblast proliferation by upregulating the expression of bFGFR1 and PCNA and ultimately accelerating the healing of PI wounds.</p>","PeriodicalId":94195,"journal":{"name":"Revista da Escola de Enfermagem da U S P","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Revista da Escola de Enfermagem da U S P
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