Pub Date : 2024-10-29DOI: 10.1016/j.jid.2024.09.019
Nina Rossa Haddad, Beita Badiei, S Leigh Curvin-Aquilla, Arieana Y Johnson, Aiden Willis, Hana B Minsky, Kaitlin L Williams, Luis A Garza
{"title":"Links Between Plastics Use, Processed Food, Sweating, and Hidradenitis Suppurativa.","authors":"Nina Rossa Haddad, Beita Badiei, S Leigh Curvin-Aquilla, Arieana Y Johnson, Aiden Willis, Hana B Minsky, Kaitlin L Williams, Luis A Garza","doi":"10.1016/j.jid.2024.09.019","DOIUrl":"https://doi.org/10.1016/j.jid.2024.09.019","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-29DOI: 10.1016/j.jid.2024.09.018
Crystal T Chang, Pirunthan Pathmarajah, Johan Allerup, Sheharbano Jafry, Kiana Yekrang, Dominique C Mitchell, Niki Ai See, Lila A Perrone, Bradley Fong, Miah D Cisneros, Roxana Daneshjou, Justin Ko, Albert S Chiou
{"title":"DDI-2: A Diverse Skin Condition Image Dataset Representing Self-Identified Asian Patients.","authors":"Crystal T Chang, Pirunthan Pathmarajah, Johan Allerup, Sheharbano Jafry, Kiana Yekrang, Dominique C Mitchell, Niki Ai See, Lila A Perrone, Bradley Fong, Miah D Cisneros, Roxana Daneshjou, Justin Ko, Albert S Chiou","doi":"10.1016/j.jid.2024.09.018","DOIUrl":"https://doi.org/10.1016/j.jid.2024.09.018","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CXCL12 and its receptor CXCR4 emerge as critical regulators within the intricate network of processes ensuring skin homeostasis. In this review, we discuss their spatial distribution and function in steady-state skin; delve into their role in acute wound healing, with emphasis on fibrotic and regenerative responses; and explore their relevance in skin responses to commensals and pathogens. Given the lack of knowledge surrounding ACKR3, the atypical receptor of CXCL12, we speculate whether and how it might be involved in the processes mentioned earlier. Is ACKR3 the (a)typical friend who enjoys missing the party, or do we need to take a closer look?
{"title":"ACKR3 in Skin Homeostasis, an Overlooked Player in the CXCR4/CXCL12 Axis.","authors":"Gabriela Cuesta-Margolles, Géraldine Schlecht-Louf, Françoise Bachelerie","doi":"10.1016/j.jid.2024.08.022","DOIUrl":"https://doi.org/10.1016/j.jid.2024.08.022","url":null,"abstract":"<p><p>CXCL12 and its receptor CXCR4 emerge as critical regulators within the intricate network of processes ensuring skin homeostasis. In this review, we discuss their spatial distribution and function in steady-state skin; delve into their role in acute wound healing, with emphasis on fibrotic and regenerative responses; and explore their relevance in skin responses to commensals and pathogens. Given the lack of knowledge surrounding ACKR3, the atypical receptor of CXCL12, we speculate whether and how it might be involved in the processes mentioned earlier. Is ACKR3 the (a)typical friend who enjoys missing the party, or do we need to take a closer look?</p>","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-26DOI: 10.1016/j.jid.2024.05.036
Elizabeth A Grice, Donna Brennan-Crispi, Natalia Rodriguez, David J Margolis, John T Seykora, George Cotsarelis, Susan C Taylor, Jamie Shuda
{"title":"Penn Academy for Skin Health (PASH): An Experiential Pipeline Program in Skin Biology and Dermatology for High-School Students.","authors":"Elizabeth A Grice, Donna Brennan-Crispi, Natalia Rodriguez, David J Margolis, John T Seykora, George Cotsarelis, Susan C Taylor, Jamie Shuda","doi":"10.1016/j.jid.2024.05.036","DOIUrl":"https://doi.org/10.1016/j.jid.2024.05.036","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-25DOI: 10.1016/j.jid.2024.07.033
Pierre A Coulombe, David Hansen, Robyn Hickerson, Alain Hovnanian, Edel A O'Toole, David P Kelsell, Holly Evans, Janice Schwartz, Eli Sprecher
{"title":"Celebrating 20 Years of the International Pachyonychia Congenita Consortium.","authors":"Pierre A Coulombe, David Hansen, Robyn Hickerson, Alain Hovnanian, Edel A O'Toole, David P Kelsell, Holly Evans, Janice Schwartz, Eli Sprecher","doi":"10.1016/j.jid.2024.07.033","DOIUrl":"https://doi.org/10.1016/j.jid.2024.07.033","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-22DOI: 10.1016/j.jid.2024.09.012
Su M Lwin, Shir Azrielant, Juan He, Christopher E M Griffiths
As medicine advances, cures are being found for diseases that were previously considered incurable, as is the case for some types of cancer. Traditionally, the term cure is reserved for resolution of disease, both at a clinical and a molecular level, which continues after cessation of treatment. Biologic therapies have revolutionized the definition of remission in severe psoriasis, with some patients achieving long-lasting disease suppression, but the disease nearly always relapses on withdrawal of the drug. Our improved understanding of the pathomechanisms of psoriasis, coupled with anecdotal reports of long-term clearance of the disease after cell-based therapies, leads us to the hypothesis that psoriasis is curable. We propose that cure of psoriasis can be achieved by restoring immune homeostasis through a combinatorial, personalized medicine approach encompassing early intervention to include biologics, advanced therapeutics, and lifestyle modification.
{"title":"Curing Psoriasis.","authors":"Su M Lwin, Shir Azrielant, Juan He, Christopher E M Griffiths","doi":"10.1016/j.jid.2024.09.012","DOIUrl":"https://doi.org/10.1016/j.jid.2024.09.012","url":null,"abstract":"<p><p>As medicine advances, cures are being found for diseases that were previously considered incurable, as is the case for some types of cancer. Traditionally, the term cure is reserved for resolution of disease, both at a clinical and a molecular level, which continues after cessation of treatment. Biologic therapies have revolutionized the definition of remission in severe psoriasis, with some patients achieving long-lasting disease suppression, but the disease nearly always relapses on withdrawal of the drug. Our improved understanding of the pathomechanisms of psoriasis, coupled with anecdotal reports of long-term clearance of the disease after cell-based therapies, leads us to the hypothesis that psoriasis is curable. We propose that cure of psoriasis can be achieved by restoring immune homeostasis through a combinatorial, personalized medicine approach encompassing early intervention to include biologics, advanced therapeutics, and lifestyle modification.</p>","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-21DOI: 10.1016/j.jid.2024.09.004
Aditya K Gupta, Mesbah Talukder, Vincent Piguet
{"title":"Mpox: A Rising Threat-2 Public Health Emergencies in 2 Years.","authors":"Aditya K Gupta, Mesbah Talukder, Vincent Piguet","doi":"10.1016/j.jid.2024.09.004","DOIUrl":"https://doi.org/10.1016/j.jid.2024.09.004","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-18DOI: 10.1016/j.jid.2024.08.001
Gerald S Lazarus, Luis A Diaz
{"title":"Lowell A. Goldsmith: Physician, Scientist, Educator, Mentor, Friend (March 29, 1938-July 10, 2024).","authors":"Gerald S Lazarus, Luis A Diaz","doi":"10.1016/j.jid.2024.08.001","DOIUrl":"https://doi.org/10.1016/j.jid.2024.08.001","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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