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The Journal of investigative dermatology最新文献

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Anti-Laminin γ1 and β4 Antibodies in Anti-p200 Pemphigoid. 抗 p200 丘疹性荨麻疹中的抗层粘蛋白 γ1 和 β4 抗体
Pub Date : 2024-11-02 DOI: 10.1016/j.jid.2024.08.033
Hiroshi Koga, Teruki Dainichi, Takashi Hashimoto
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引用次数: 0
Blue Light-Induced Pigmentation. 蓝光诱导的色素沉着。
Pub Date : 2024-11-02 DOI: 10.1016/j.jid.2024.09.015
Indermeet Kohli, Henry W Lim
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引用次数: 0
MicroRNA Quantification as an Accurate and Cost-Effective Method to Diagnose Acral Melanoma. MicroRNA 定量是诊断口腔黑色素瘤的一种准确而经济的方法。
Pub Date : 2024-11-01 DOI: 10.1016/j.jid.2024.09.002
Claudia Gutiérrez-García, Carla Daniela Robles-Espinoza
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引用次数: 0
Utilization of Computable Phenotypes in Electronic Health Record Research: A Review and Case Study in Atopic Dermatitis. 在电子健康记录研究中利用可计算表型:特应性皮炎回顾与病例研究。
Pub Date : 2024-11-01 DOI: 10.1016/j.jid.2024.08.025
Joseph Masison, Harold P Lehmann, Joy Wan

Querying electronic health records databases to accurately identify specific cohorts of patients has countless observational and interventional research applications. Computable phenotypes are computationally executable, explicit sets of selection criteria composed of data elements, logical expressions, and a combination of natural language processing and machine learning techniques enabling expedited patient cohort identification. Phenotyping encompasses a range of implementations, each with advantages and use cases. In this paper, the dermatologic computable phenotype literature is reviewed. We identify and evaluate approaches and community supports for computable phenotyping that have been used both generally and within dermatology and, as a case study, focus on studied phenotypes for atopic dermatitis.

查询电子健康记录数据库以准确识别特定的患者群,在观察和干预研究中有着无数的应用。可计算表型是可计算执行的、明确的选择标准集,由数据元素、逻辑表达式以及自然语言处理和机器学习技术组合而成,可加快患者队列的识别。表型包括一系列实现方法,每种方法都有其优势和用例。本文回顾了皮肤科可计算表型文献。我们确定并评估了在皮肤病学领域普遍使用的可计算表型方法和社区支持,并以特应性皮炎的表型研究为案例进行了重点分析。
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引用次数: 0
A Geospatial Analysis of the Association between Access to Tanning Bed Facilities and Melanoma in the United States New England Region. 美国新英格兰地区使用日光浴浴床设施与黑色素瘤之间关系的地理空间分析》(A Geospatial Analysis of the Association between Access to Tanning Bed Facilities and Melanoma in the United States New England Region)。
Pub Date : 2024-11-01 DOI: 10.1016/j.jid.2024.04.038
Guixing Wei, Megan M Tran, Lauryn Orsillo, Fatima N Mirza, Sara Yumeen, Eric Yang, Allison Robbins, Aakash Mehta, Zhijun Liu, Terrence Vance, John Kawaoka, Abrar A Qureshi, Oliver J Wisco

Substantial geographic disparities in melanoma incidence and access to tanning bed facilities exist. In this spatial ecological study, we evaluate the relationship between access to tanning bed facilities and melanoma incidence. New England county-level melanoma incidence rates (2014-2018), tanning bed facilities location, demographic data, socioeconomic data, and geographic data were obtained from the National Cancer Institute State Cancer Profiles, Data Axle, American Community Survey, and United States Geological Survey. Spatial regression models were utilized to determine the association between melanoma incidence and access to tanning beds, adjusting for confounding factors. Adjusted spatial regression identified that for every 1-minute increase in average travel time to tanning facilities within 30 minutes travel time threshold, the melanoma incidence rate decreased by 3.46% in the same county and by 1.92% across New England. We found a negative association between average travel time to tanning facilities and county-level melanoma incidence rate, suggesting that policy aimed at decreasing access to indoor tanning facilities has the potential to reduce melanoma rates. High-risk clusters, with respect to county-level melanoma rate, were also identified. Targeting of interventions and resources to high-risk clusters may reduce geographic melanoma rates disparities.

黑色素瘤的发病率与日光浴床设施的使用存在巨大的地域差异。在这项空间生态研究中,我们评估了使用日光浴床设施与黑色素瘤发病率之间的关系。新英格兰郡级黑色素瘤发病率(2014-2018 年)、日光浴床设施位置、人口数据、社会经济数据和地理数据均来自美国国家癌症研究所州癌症概况、数据轴、美国社区调查和美国地质调查局。在对混杂因素进行调整后,利用空间回归模型确定黑色素瘤发病率与使用日光浴床之间的关系。调整后的空间回归结果表明,在 30 分钟旅行时间临界值内,前往日光浴设施的平均旅行时间每增加 1 分钟,同一郡的黑色素瘤发病率就会下降 3.46%,整个新英格兰地区的发病率则会下降 1.92%。我们发现,前往日晒设施的平均交通时间与县级黑色素瘤发病率之间存在负相关,这表明旨在减少室内日晒设施使用的政策有可能降低黑色素瘤发病率。此外,还确定了与县级黑色素瘤发病率有关的高风险集群。针对高风险集群采取干预措施并提供资源,可能会减少黑色素瘤发病率的地域差异。
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引用次数: 0
Intrinsic regulatory mechanisms protect human skin mast cells from excessive MRGPRX2 activation - paucity in LAD2 cells contributes to hyperresponsiveness of the mast cell line. 内在调控机制保护人类皮肤肥大细胞免受 MRGPRX2 的过度激活--LAD2 细胞中 MRGPRX2 的缺乏导致了肥大细胞系的高反应性。
Pub Date : 2024-10-29 DOI: 10.1016/j.jid.2024.10.593
Zhuoran Li, Jean Schneikert, Gürkan Bal, Manqiu Jin, Kristin Franke, Torsten Zuberbier, Magda Babina
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引用次数: 0
Topical ivermectin treatment of rosacea changes the bacterial microbiome of the skin. 酒糟鼻的局部伊维菌素治疗会改变皮肤的细菌微生物群。
Pub Date : 2024-10-29 DOI: 10.1016/j.jid.2024.10.592
Teruaki Nakatsuji, Joyce Y Cheng, Anna Butcher, Faiza Shafiq, Olive Osuoji, Richard L Gallo, Tissa R Hata
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引用次数: 0
Links between Plastics Use, Processed Food, Sweating, and Hidradenitis Suppurativa. 使用塑料、加工食品、出汗与扁平苔癣之间的联系
Pub Date : 2024-10-29 DOI: 10.1016/j.jid.2024.09.019
Nina Rossa Haddad, Beita Badiei, S Leigh Curvin-Aquilla, Arieana Y Johnson, Aiden Willis, Hana B Minsky, Kaitlin L Williams, Luis A Garza
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引用次数: 0
DDI-2: A Diverse Skin Condition Image Dataset Representing Self-Identified Asian Patients. DDI-2:代表自我认定的亚洲患者的多种皮肤状况图像数据集。
Pub Date : 2024-10-29 DOI: 10.1016/j.jid.2024.09.018
Crystal T Chang, Pirunthan Pathmarajah, Johan Allerup, Sheharbano Jafry, Kiana Yekrang, Dominique C Mitchell, Niki Ai See, Lila A Perrone, Bradley Fong, Miah D Cisneros, Roxana Daneshjou, Justin Ko, Albert S Chiou
{"title":"DDI-2: A Diverse Skin Condition Image Dataset Representing Self-Identified Asian Patients.","authors":"Crystal T Chang, Pirunthan Pathmarajah, Johan Allerup, Sheharbano Jafry, Kiana Yekrang, Dominique C Mitchell, Niki Ai See, Lila A Perrone, Bradley Fong, Miah D Cisneros, Roxana Daneshjou, Justin Ko, Albert S Chiou","doi":"10.1016/j.jid.2024.09.018","DOIUrl":"https://doi.org/10.1016/j.jid.2024.09.018","url":null,"abstract":"","PeriodicalId":94239,"journal":{"name":"The Journal of investigative dermatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ACKR3 in Skin Homeostasis, an Overlooked Player in the CXCR4/CXCL12 Axis. 皮肤稳态中的 ACKR3--CXCR4/CXCL12 轴中被忽视的角色
Pub Date : 2024-10-28 DOI: 10.1016/j.jid.2024.08.022
Gabriela Cuesta-Margolles, Géraldine Schlecht-Louf, Françoise Bachelerie

CXCL12 and its receptor CXCR4 emerge as critical regulators within the intricate network of processes ensuring skin homeostasis. In this review, we discuss their spatial distribution and function in steady-state skin; delve into their role in acute wound healing, with emphasis on fibrotic and regenerative responses; and explore their relevance in skin responses to commensals and pathogens. Given the lack of knowledge surrounding ACKR3, the atypical receptor of CXCL12, we speculate whether and how it might be involved in the processes mentioned earlier. Is ACKR3 the (a)typical friend who enjoys missing the party, or do we need to take a closer look?

CXCL12 及其受体 CXCR4 是确保皮肤稳态的复杂过程网络中的关键调节因子。在这篇综述中,我们将讨论它们在稳态皮肤中的空间分布和功能;深入探讨它们在急性伤口愈合中的作用,重点是纤维化和再生反应;并探讨它们在皮肤对寄生虫和病原体的反应中的相关性。鉴于对 CXCL12 的非典型受体 ACKR3 缺乏了解,我们推测它是否以及如何参与上述过程。ACKR3 是喜欢错过聚会的(典型)朋友,还是我们需要仔细观察一下?
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引用次数: 0
期刊
The Journal of investigative dermatology
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