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Leitlinien beeinflussen wie kein anderes inhaltliches Instrument die tägliche Patientenversorgung. 指南对患者日常护理的影响是其他与内容相关的工具所无法比拟的。
Pub Date : 2024-10-01 Epub Date: 2024-09-25 DOI: 10.1055/a-2381-1391
Matthias Manych
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引用次数: 0
Medizinische Leitlinien – anerkannte praxisrelevante Orientierungshilfe mit Modernisierungsbedarf. 医疗指南--公认的实用指南,但需要现代化。
Pub Date : 2024-10-01 Epub Date: 2024-09-25 DOI: 10.1055/a-2381-1156
Matthias Manych
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引用次数: 0
Editorial. 社论
Pub Date : 2024-10-01 Epub Date: 2024-09-25 DOI: 10.1055/a-2356-2063
Andreas Seekamp, Markus Scheibel, Tobias Vogel
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引用次数: 0
Quality of Life with Respect to Surgically Treated Vertebral Osteomyelitis and Degenerative Spondylolisthesis. 外科治疗的脊椎骨髓炎和退行性脊柱炎患者的生活质量。
Pub Date : 2024-10-01 Epub Date: 2023-09-22 DOI: 10.1055/a-2151-5022
Frank Beyer, Ayla Yagdiran, Peer Eysel, Jan Bredow

Vertebral osteomyelitis (VO) and degenerative spondylolisthesis (SL) are 2 commonly treated spinal conditions. Therefore, in the presented work, the quality of life after surgical therapy of these 2 entities is compared using established scores.In a monocentric study, all patients with VO and SL were prospectively enrolled using the Spine Tango Registry. Surgical procedures included one- or two-stage fusion of the affected segments. Quality of life was assessed using the Core Outcome Measures Index (COMI) and the Oswestry Disability Index (ODI) at time points t0 (0 months), t1 (12 months), and t2 (24 months). Statistical analysis was performed using SPSS. The level of significance was set at 5%.52 patients with VO and 48 patients with SL were included in the analysis. There were no significant differences in age and gender distribution. The length of stay in the SL group was significantly shorter (p < 0.001). ODI at time t0 was significantly higher in the VO group (p < 0.001), whereas COMI scores did not differ significantly (p = 0.155). At time points t1 and t2, the differences between the VO and SL groups were not significantly different for either the ODI score (p = 0.176; p = 0.250) or the COMI score (p = 0.682; p = 0.640).Postoperative quality of life scores after lumbar fusion surgery in SL and VO are comparable despite different indications and medical conditions. In both groups, similar quality of life with in patient with chronic back pain was achieved. This should be considered for the preoperative assessment, as well as for the indication for surgery in SL.

脊椎骨髓炎(VO)和退行性脊椎滑脱(SL)是两种常见的脊柱疾病。因此,在所提出的工作中,使用已建立的评分来比较这两个实体的手术治疗后的生活质量。在一项单中心研究中,所有VO和SL患者都使用Spine Tango注册表进行了前瞻性入组。外科手术包括对受影响的节段进行一次或两次融合。在t0(0个月)、t1(12个月)和t2(24个月)时间点,使用核心结果测量指数(COMI)和奥斯韦斯特里残疾指数(ODI)评估生活质量。采用SPSS软件进行统计分析。显著性水平设定为5%。52名VO患者和48名SL患者被纳入分析。年龄和性别分布没有显著差异。SL组的住院时间明显缩短(p
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引用次数: 0
"Fall Risk Scoring" in Outpatient Gait Analysis: Validation of a New Fall Risk Assessment for Nursing Home Residents. 门诊步态分析中的“跌倒风险评分”:疗养院居民跌倒风险评估的新验证。
Pub Date : 2024-10-01 Epub Date: 2023-10-09 DOI: 10.1055/a-2151-4709
Eduard Witiko Unger, Tim Pohlemann, Marcel Orth, Mika F R Rollmann, Maximilian M Menger, Steven C Herath, Tina Histing, Benedikt J Braun

Falls in senior home residents are common. Individual preventive training can lower the fall risk. To detect the need for training, a systematic assessment of the individual fall risk is needed. The aim of this study was thus to assess whether a fall risk score based on free field insole measurements can distinguish between an at-risk group of senior home residents and a healthy young control group. A published fall risk score was used in senior home residents over the age of 75 and a young (< 40 years) control group to determine the individual fall risk. In addition, the fall events over 12 months were assessed. Statistical analysis including ROC analysis was performed to determine the ability of the score to detect participants at heightened fall risk. In total, 18 nursing home residents and 9 young control participants were included. Of the nursing home residents, 15 had at least one fall, with a total of 37 falls recorded over 12 months. In the control group, no falls were recorded. The fall risk score was significantly different between nursing home residents and the control group (9.2 + 3.2 vs. 5.7 ± 2.2). Furthermore, the score significantly differentiated fallers from non-fallers (10.3 ± 1.8 vs. 5.2 ± 2.5), with a cut-off > 7.5 (AUC: 0.95) and a sensitivity of 86.7% (specificity 83.3%). The fall risk score is able to detect the difference between senior nursing home residents and young, healthy controls, as well as between fallers and non-fallers. Its main proof of concept is demonstrated, as based on movement data outside special gait labs, and it can simplify the risk of fall determination in geriatric nursing home residents and can now be used in further, prospective studies.

老年家庭住户摔倒的情况很常见。个人预防性训练可以降低跌倒风险。为了发现训练的必要性,需要对个人跌倒风险进行系统评估。因此,本研究的目的是评估基于自由场地鞋垫测量的跌倒风险评分是否可以区分老年家庭居民的风险组和健康的年轻对照组。已公布的跌倒风险评分用于75岁以上的养老院居民和一名年轻人(7.5(AUC:0.95),敏感性为86.7%(特异性83.3%)。跌倒风险评分能够检测养老院老年居民和年轻健康对照之间以及跌倒者和非跌倒者之间的差异。它的主要概念验证是基于特殊步态实验室外的运动数据进行的,它可以简化老年疗养院居民跌倒风险的确定,现在可以用于进一步的前瞻性研究。
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引用次数: 0
XV. DGORh-Intensivmeeting in Kiel: Beitragsstrukturreform beschlossen. 在基尔举行的第 XV 届 DGORh 强化会议:就会费结构改革达成一致。
Pub Date : 2024-10-01 Epub Date: 2024-09-25 DOI: 10.1055/a-2352-8599
Ralph Gaulke, Babak Moradi
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引用次数: 0
[Double-Level De-Rotational Osteotomy of the Knee]. [膝关节双层去旋转截骨术]。
Pub Date : 2024-10-01 Epub Date: 2024-01-19 DOI: 10.1055/a-2232-3506
Felix Ferner, Christoph Lutter, Mario Perl, Jörg Harrer

Derotational osteotomies of the proximal tibia and distal femur are a common surgical treatment option in patients with a congenital or posttraumatic torsional deformity. Clinically, these patients present with isolated anterior knee pain alone or in in combination with patellofemoral instability. Since the combination of femoral and tibial deformity is common (quotation Cooke), a combined surgical treatment is needed for these cases. This includes high tibial derotational and a distal femoral osteotomy, stabilised by a plate respectively. The current video shows the technique of this combined osteotomy assisted by external fixateur and the tibial approach with tibialis anterior fasciectomy and neurolysis of the peroneal nerve.

胫骨近端和股骨远端截骨术是先天性或创伤后扭转畸形患者常见的手术治疗方法。在临床上,这些患者表现为单独的膝关节前部疼痛或合并髌骨股骨不稳定。由于股骨畸形和胫骨畸形并存的情况很常见(引用库克的话),因此需要对这些病例进行联合手术治疗。这包括胫骨高位脱位和股骨远端截骨,并分别用钢板加以稳定。当前的视频展示了这种由外固定器辅助的联合截骨术,以及胫骨入路与胫骨前筋膜切除术和腓总神经神经溶解术。
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引用次数: 0
Comparison of Pre- and Postoperative Motor-proprioceptive Abilities in Patients with Gonarthrosis. 膝关节病患者术前和术后运动本体感受能力的比较。
Pub Date : 2024-10-01 Epub Date: 2023-10-05 DOI: 10.1055/a-2151-4849
Viktoria Schröter, Clemens Könczöl, Jens O Anders

Both surgeons and patients want to achieve a high level of satisfaction and the best possible functional results within a short time after knee TEP surgery. By using a tool that digitally records various measurement parameters of balance and motor function preoperatively and postoperatively on a mobile basis and with little time expenditure, progressive results can be compared. Individual factors can thus be determined and these can influence the progress in regeneration and training progress perioperatively.In a prospective study, 100 patients before and 66 patients after installation of a cement-retained knee TEP were evaluated for the following parameters: balance, maximum strength, and power. All measurements were performed with the KMP measurement platform from MotoSana. The second measurements were performed in each case after a standardised follow-up treatment.It was shown that there are significant relationships between personal factors such as age, height, body weight and with baseline values and performance measures: maximum strength and power. Furthermore, it was shown that postoperative improvement could be achieved for the most part around balance support. All patients who previously had to hold on with one hand or both hands no longer needed support after surgery to maintain the single-leg stance for the specified time of 15 s. For a more detailed analysis of the balance parameters, the samples were adjusted and only the patients who did not hold on for support pre- and postoperatively were counted. In patients with low and medium initial stance, the sway area increased at the second measurement session, and in patients with large sway areas, it decreased, and the stance became more stable. In the area of maximum strength and power, patients with high baseline values still had higher values after AHB compared with the other patients, but lower values compared with their own baseline values.Patients who already had very good motor skills before surgery were able to achieve a greater increase in motor skills compared to the weaker group. However, all patients failed to reach their preoperative baseline values after completion of the AHB. Deficits in balance were still detectable in all groups. By using the presented force plate, measurement-based coordinated rehabilitation procedures are possible during and after completion of the AHB. Rehabilitation with individualised improvement of balance and motor function could be expected to prevent dissatisfaction after knee arthroplasty, e.g. due to muscular imbalance in femoropatellar pain syndromes.

外科医生和患者都希望在膝关节TEP手术后的短时间内获得高水平的满意度和尽可能好的功能结果。通过使用一种工具,在移动的基础上,以数字方式记录术前和术后平衡和运动功能的各种测量参数,并且只需很少的时间,就可以比较渐进的结果。因此,可以确定个体因素,这些因素可以影响再生和训练的进展。在一项前瞻性研究中,对100名患者在安装水泥保留膝关节TEP之前和66名患者进行了以下参数的评估:平衡、最大强度和力量。所有测量均使用MotoSana的KMP测量平台进行。在标准化的随访治疗后,对每个病例进行第二次测量。研究表明,年龄、身高、体重等个人因素与基线值和表现指标(最大力量和力量)之间存在显著关系。此外,研究表明,术后的改善在很大程度上可以通过平衡支撑来实现。所有以前必须用一只手或两只手坚持的患者在手术后不再需要支撑,以在15 s的指定时间内保持单腿姿势。为了对平衡参数进行更详细的分析,对样本进行了调整,只对术前和术后没有坚持支持的患者进行了计数。在初始姿势较低和中等的患者中,摇摆区域在第二次测量时增加,在摇摆区域较大的患者中减少,姿势变得更加稳定。在最大力量和力量方面,与其他患者相比,基线值较高的患者在AHB后仍然具有较高的值,但与他们自己的基线值相比具有较低的值。与较弱的组相比,在手术前已经有很好运动技能的患者能够在运动技能方面获得更大的提高。然而,所有患者在完成AHB后均未能达到术前基线值。在所有组中仍然可以检测到平衡缺陷。通过使用所提出的力板,可以在AHB期间和之后进行基于测量的协调康复程序。通过个性化改善平衡和运动功能的康复有望防止膝关节置换术后的不满,例如由于股髌疼痛综合征中的肌肉失衡。
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引用次数: 0
[Blood Products and Stem Cells in Osteoarthritis Therapy]. [骨关节炎治疗中的血液制品和干细胞]。
Pub Date : 2024-10-01 Epub Date: 2024-09-25 DOI: 10.1055/a-2192-8330
Alexander Otahal, Markus Neubauer, Stefan Nehrer

The principle of regenerative medicine in the treatment of osteoarthritis pursues a functional restoration of cartilage tissue instead of just repairing cartilage defects. The use of blood products is intended to inhibit chronic inflammatory processes and promote tissue regeneration. Intraarticular injection of autologous platelet-rich plasma (PRP) is a prominent procedure. Clinical evidence supports PRP injection over hyaluronic acid or glucocorticoid injection. Comparability of studies is difficult due to missing standardisation of production procedures, dosing and donor variability. In particular, whether presence of residual leukocytes is required or should be avoided is an open debate. In contrast, stem cell therapies in osteoarthritis therapy are often based on mesenchymal stem cells (MSC) from adipose tissue or bone marrow aspirate. Different sources of MSC might render the cells more suitable for application in a given context. Nevertheless, it became evident that their secretome rather than the cells themselves are responsible for observed regenerative processes. Research on the mechanisms of action have focused on growth factors. However, an overlooked component of blood products called extracellular vesicles (EV) came to the center of attention, which are also released by MSC as intercellular signal carriers. EV cargo molecules such as miRNAs open up new dimensions in the investigation and explanation of clinically observed anti-inflammatory and regenerative effects.

再生医学治疗骨关节炎的原则是追求软骨组织的功能恢复,而不仅仅是修复软骨缺损。使用血液制品的目的是抑制慢性炎症过程,促进组织再生。关节内注射自体富血小板血浆(PRP)是一种重要的治疗方法。临床证据表明,PRP 注射优于透明质酸或糖皮质激素注射。由于缺乏标准化的生产程序、剂量和供体的差异性,研究的可比性很难保证。特别是,是否需要或应避免残留白细胞的存在是一个公开辩论的问题。相比之下,骨关节炎治疗中的干细胞疗法通常以脂肪组织或骨髓抽吸物中的间充质干细胞(MSC)为基础。间充质干细胞的不同来源可能会使细胞更适合在特定情况下应用。尽管如此,在观察到的再生过程中,显然是细胞的分泌物而不是细胞本身在起作用。对作用机制的研究主要集中在生长因子上。然而,血液制品中一种被忽视的成分--细胞外囊泡(EV)成为了关注的焦点,它也是间充质干细胞释放的细胞间信号载体。EV载货分子(如 miRNAs)为研究和解释临床观察到的抗炎和再生效应开辟了新的领域。
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引用次数: 0
The S2e Guideline on Shoulder Stiffness. S2e肩部硬度指南。
Pub Date : 2024-10-01 Epub Date: 2023-10-05 DOI: 10.1055/a-2123-4952
Friedrich Dehlinger, Ulf Bökeler, Hanna Brandt, Lars Brunnader, Lars Eden, Andrea Pfingsten, Robert Prill

The clinical picture of "frozen shoulder" is still poorly understood. In order to present the current state of knowledge on aetiology, diagnosis, and treatment, and to provide recommendations for the professional groups involved, a working group was formed by the DGOU and the DVSE to create a German language, evidence-based guideline, which was published in 2022 by the AWMF. The following summarises the development and the most important results.

对“冻肩”的临床表现仍知之甚少。为了介绍病因、诊断和治疗方面的知识现状,并为相关专业团体提供建议,DGOU和DVSE成立了一个工作组,以创建一份德语循证指南,该指南由AWMF于2022年发布。以下总结了发展和最重要的结果。
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引用次数: 0
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Zeitschrift fur Orthopadie und Unfallchirurgie
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