首页 > 最新文献

Singapore medical journal最新文献

英文 中文
Prevalence and risk factors of symptomatic venous thromboembolism in distal femur fractures. 股骨远端骨折患者无症状静脉血栓栓塞症的发病率和风险因素。
Pub Date : 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2023-265
Wei Mao, Joel Xue Yi Lim, Jiong Hao Tan, Shi-Min Chang, Choon Chiet Hong

Introduction: There is a paucity of published research on symptomatic venous thromboembolism (sVTE) after distal femur fractures (DFFs). This study aimed to explore the prevalence and risk factors of sVTE in DFFs.

Methods: We identified a total of 131 patients who underwent DFF surgeries without routine pharmacological thromboprophylaxis between October 2007 and November 2016. Cases of sVTE included symptomatic pulmonary embolism (sPE) and symptomatic deep vein thrombosis (sDVT). Patients with sVTE were compared to those without, and differences in demographics and fracture-related characteristics were explored. Multivariate logistic regression was used to eliminate confounding factors.

Results: Of the 131 patients, 20 (15.3%) had sVTE, of whom 16 (12.2%) had sDVT and six (4.6%) had sPE (two patients had both sPE and sDVT). Notably, 17 (85.0%) sVTE patients were aged ≥60 years, while only 62 (55.9%) non-sVTE patients were aged ≥60 years (P = 0.014). Fourteen (82.4%) patients with sVTE had body mass index (BMI) ≥25 kg/m2, while 49 (53.3%) patients without sVTE had BMI ≥25 kg/m2 (P = 0.032). Multivariate logistic regression demonstrated that age ≥60 years (adjusted odds ratio [OR] 5.05; P = 0.040) and BMI ≥25 kg/m2 (adjusted OR 3.92; P = 0.045) were independently associated with a higher risk of sVTE after DFF.

Conclusion: The prevalence of sVTE in DFFs is high at 15.3%. Advanced age (≥60 years) and being overweight (BMI ≥25 kg/m2) were two independent risk factors for sVTE in DFFs. The use of routine pharmacological thromboprophylaxis should be considered as a preventative measure.

简介:关于股骨远端骨折(DFF)后无症状静脉血栓栓塞症(sVTE)的公开研究很少。本研究旨在探讨股骨远端骨折后症状性静脉血栓栓塞症的发病率和风险因素:我们确定了 2007 年 10 月至 2016 年 11 月间接受 DFF 手术且未进行常规药物血栓预防治疗的 131 例患者。sVTE病例包括症状性肺栓塞(sPE)和症状性深静脉血栓形成(sDVT)。将患有 sVTE 的患者与未患有 sVTE 的患者进行了比较,并探讨了人口统计学和骨折相关特征的差异。采用多变量逻辑回归消除混杂因素:在 131 名患者中,20 人(15.3%)患有 sVTE,其中 16 人(12.2%)患有 sDVT,6 人(4.6%)患有 sPE(两名患者同时患有 sPE 和 sDVT)。值得注意的是,17 名 sVTE 患者(85.0%)的年龄≥60 岁,而只有 62 名非 sVTE 患者(55.9%)的年龄≥60 岁(P = 0.014)。14名(82.4%)sVTE 患者的体重指数(BMI)≥25 kg/m2,而 49 名(53.3%)非 sVTE 患者的体重指数≥25 kg/m2(P = 0.032)。多变量逻辑回归显示,年龄≥60 岁(调整后的比值比 [OR] 5.05;P = 0.040)和体重指数≥25 kg/m2(调整后的比值比 3.92;P = 0.045)与 DFF 后较高的 sVTE 风险独立相关:结论:DFF术后sVTE的发生率高达15.3%。高龄(≥60 岁)和超重(体重指数≥25 kg/m2)是 DFF 中发生 sVTE 的两个独立风险因素。应考虑将常规药物血栓预防作为一种预防措施。
{"title":"Prevalence and risk factors of symptomatic venous thromboembolism in distal femur fractures.","authors":"Wei Mao, Joel Xue Yi Lim, Jiong Hao Tan, Shi-Min Chang, Choon Chiet Hong","doi":"10.4103/singaporemedj.SMJ-2023-265","DOIUrl":"https://doi.org/10.4103/singaporemedj.SMJ-2023-265","url":null,"abstract":"<p><strong>Introduction: </strong>There is a paucity of published research on symptomatic venous thromboembolism (sVTE) after distal femur fractures (DFFs). This study aimed to explore the prevalence and risk factors of sVTE in DFFs.</p><p><strong>Methods: </strong>We identified a total of 131 patients who underwent DFF surgeries without routine pharmacological thromboprophylaxis between October 2007 and November 2016. Cases of sVTE included symptomatic pulmonary embolism (sPE) and symptomatic deep vein thrombosis (sDVT). Patients with sVTE were compared to those without, and differences in demographics and fracture-related characteristics were explored. Multivariate logistic regression was used to eliminate confounding factors.</p><p><strong>Results: </strong>Of the 131 patients, 20 (15.3%) had sVTE, of whom 16 (12.2%) had sDVT and six (4.6%) had sPE (two patients had both sPE and sDVT). Notably, 17 (85.0%) sVTE patients were aged ≥60 years, while only 62 (55.9%) non-sVTE patients were aged ≥60 years (P = 0.014). Fourteen (82.4%) patients with sVTE had body mass index (BMI) ≥25 kg/m2, while 49 (53.3%) patients without sVTE had BMI ≥25 kg/m2 (P = 0.032). Multivariate logistic regression demonstrated that age ≥60 years (adjusted odds ratio [OR] 5.05; P = 0.040) and BMI ≥25 kg/m2 (adjusted OR 3.92; P = 0.045) were independently associated with a higher risk of sVTE after DFF.</p><p><strong>Conclusion: </strong>The prevalence of sVTE in DFFs is high at 15.3%. Advanced age (≥60 years) and being overweight (BMI ≥25 kg/m2) were two independent risk factors for sVTE in DFFs. The use of routine pharmacological thromboprophylaxis should be considered as a preventative measure.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between parental bonding and health-related quality of life in a clinical sample of youths aged 14-35 years in Singapore. 新加坡 14-35 岁青少年临床样本中父母亲情与健康相关生活质量之间的关系。
Pub Date : 2024-10-01 Epub Date: 2024-07-11 DOI: 10.4103/singaporemedj.SMJ-2023-223
Yoke Boon Tan, Eng Hong Tay, Shazana Shahwan, Yunjue Zhang, Rajeswari Sambasivam, Mythily Subramaniam

Introduction: Individuals with psychiatric disorders tend to report having poorer bonds with their parents during their early years. These individuals often experience lower quality of life as well. This study investigated the associations between aspects of parental bonding and health-related quality of life (HRQOL) in a clinical sample of youths. It was hypothesised that high parental care and low parental overprotectiveness would be associated with higher levels of HRQOL.

Methods: Data were obtained from a larger cross-sectional study. The sample consisted of 400 psychiatric outpatients: 191 patients aged 14-21 (mean ± standard deviation 18.1 ± 2.22) years and 209 patients aged 22-35 (28.0 ± 4.33) years. The Parental Bonding Instrument was used to measure parental care and overprotectiveness. Short Form-12 measured physical health (physical component summary [PCS]) and mental health (mental component summary [MCS]) components of HRQOL, and the 8-item Patient Health Questionnaire assessed depressive symptoms. These scales and a sociodemographic form were self-administered. Multivariable linear regression was used for analysis.

Results: About half of the sample reported affectionless control for mothers (46.6%) and fathers (45.9%). After controlling for sociodemographic variables, no significant relationship was found between aspects of parental bonding and PCS scores. Maternal care was associated with MCS scores (β = 0.32, P < 0.01) and PHQ-8 scores (β = -0.12, P < 0.05).

Conclusion: Our results suggest that youths who experienced quality care from their mothers exhibit better mental health functioning despite their clinical diagnoses, which suggests that early maternal care exerts an overall long-term protective effect. Early parental education that promotes positive parenting practices could improve the overall HRQOL of individuals in adulthood despite their clinical diagnoses.

导言患有精神障碍的人往往表示,他们早年与父母的关系较差。这些人的生活质量通常也较低。本研究调查了临床青少年样本中父母亲情与健康相关生活质量(HRQOL)之间的关系。研究假设,父母的高度关爱和低度过度保护将与较高的 HRQOL 水平相关:数据来自一项大型横断面研究。样本由 400 名精神病门诊患者组成:191名患者的年龄为14-21岁(平均±标准差为18.1±2.22)岁,209名患者的年龄为22-35岁(28.0±4.33)岁。父母关系测量工具用于测量父母的关爱和过度保护。简表-12测量了HRQOL的身体健康(身体部分摘要[PCS])和心理健康(心理部分摘要[MCS])部分,8项患者健康问卷评估了抑郁症状。这些量表和一份社会人口调查表均为自填。分析采用多变量线性回归法:约有一半的样本报告称母亲(46.6%)和父亲(45.9%)缺乏亲情控制。在控制了社会人口学变量后,没有发现父母亲子关系的各个方面与 PCS 分数之间有明显的关系。母亲关怀与 MCS 分数(β = 0.32,P < 0.01)和 PHQ-8 分数(β = -0.12,P < 0.05)相关:我们的研究结果表明,经历过母亲优质照顾的青少年尽管有临床诊断,但他们的心理健康功能却更好,这表明母亲的早期照顾具有长期的整体保护作用。促进积极养育方式的早期父母教育可以改善成年后个人的整体 HRQOL,尽管他们有临床诊断。
{"title":"Associations between parental bonding and health-related quality of life in a clinical sample of youths aged 14-35 years in Singapore.","authors":"Yoke Boon Tan, Eng Hong Tay, Shazana Shahwan, Yunjue Zhang, Rajeswari Sambasivam, Mythily Subramaniam","doi":"10.4103/singaporemedj.SMJ-2023-223","DOIUrl":"10.4103/singaporemedj.SMJ-2023-223","url":null,"abstract":"<p><strong>Introduction: </strong>Individuals with psychiatric disorders tend to report having poorer bonds with their parents during their early years. These individuals often experience lower quality of life as well. This study investigated the associations between aspects of parental bonding and health-related quality of life (HRQOL) in a clinical sample of youths. It was hypothesised that high parental care and low parental overprotectiveness would be associated with higher levels of HRQOL.</p><p><strong>Methods: </strong>Data were obtained from a larger cross-sectional study. The sample consisted of 400 psychiatric outpatients: 191 patients aged 14-21 (mean ± standard deviation 18.1 ± 2.22) years and 209 patients aged 22-35 (28.0 ± 4.33) years. The Parental Bonding Instrument was used to measure parental care and overprotectiveness. Short Form-12 measured physical health (physical component summary [PCS]) and mental health (mental component summary [MCS]) components of HRQOL, and the 8-item Patient Health Questionnaire assessed depressive symptoms. These scales and a sociodemographic form were self-administered. Multivariable linear regression was used for analysis.</p><p><strong>Results: </strong>About half of the sample reported affectionless control for mothers (46.6%) and fathers (45.9%). After controlling for sociodemographic variables, no significant relationship was found between aspects of parental bonding and PCS scores. Maternal care was associated with MCS scores (β = 0.32, P < 0.01) and PHQ-8 scores (β = -0.12, P < 0.05).</p><p><strong>Conclusion: </strong>Our results suggest that youths who experienced quality care from their mothers exhibit better mental health functioning despite their clinical diagnoses, which suggests that early maternal care exerts an overall long-term protective effect. Early parental education that promotes positive parenting practices could improve the overall HRQOL of individuals in adulthood despite their clinical diagnoses.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of soft tissue emphysema in emergency head and neck imaging. 在急诊头颈部成像中检测软组织气肿。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2021-453
Michael Che Hao Seng, Elena Tangtra, Chi Long Ho
{"title":"Detection of soft tissue emphysema in emergency head and neck imaging.","authors":"Michael Che Hao Seng, Elena Tangtra, Chi Long Ho","doi":"10.4103/singaporemedj.SMJ-2021-453","DOIUrl":"10.4103/singaporemedj.SMJ-2021-453","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No health without mental health: united we stand. 没有心理健康就没有健康:我们团结一致。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2024-182
Kang Sim, Tiing Leong Ang
{"title":"No health without mental health: united we stand.","authors":"Kang Sim, Tiing Leong Ang","doi":"10.4103/singaporemedj.SMJ-2024-182","DOIUrl":"10.4103/singaporemedj.SMJ-2024-182","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigma and mental health: overcoming barriers. 耻辱与心理健康:克服障碍。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2024-166
Mythily Subramaniam
{"title":"Stigma and mental health: overcoming barriers.","authors":"Mythily Subramaniam","doi":"10.4103/singaporemedj.SMJ-2024-166","DOIUrl":"10.4103/singaporemedj.SMJ-2024-166","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between treatment resistance and cognitive function in schizophrenia. 精神分裂症患者的耐药性与认知功能之间的关系。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2024-143
Jiaqian Sun, Jie Yin Yee, Yuen Mei See, Charmaine Tang, Shushan Zheng, Boon Tat Ng, Jimmy Lee

Introduction: Treatment-resistant schizophrenia (TRS) affects around 30% of individuals with schizophrenia. About half of the patients with TRS who are treated with clozapine do not show a meaningful clinical response, that is, clozapine resistance. To date, the relationship between cognitive function and treatment response categories is not entirely clear. This study evaluated the cognitive performance across subgroups stratified by treatment response, and we hypothesised that cognitive impairment increases with increased treatment resistance.

Methods: This study was conducted at the Institute of Mental Health, Singapore, and included healthy controls and people with schizophrenia categorised into these groups: antipsychotic-responsive schizophrenia (ARS), clozapine-responsive TRS (TRS-CR) and clozapine-resistant TRS (ultra-treatment-resistant schizophrenia [UTRS]). Cognitive function was assessed using the Brief Assessment of Cognition-Short Form. Symptoms were measured with the Positive and Negative Syndrome Scale (PANSS). The planned statistical analyses included adjustments for covariates such as age, sex, PANSS scores and antipsychotic dose, which might affect cognitive function.

Results: There were significant differences in overall cognitive performance between the groups: ARS had the least impairment, followed by TRS-CR and UTRS. Antipsychotic dose, and PANSS negative and disorganisation/cognitive factors were significant predictors of overall cognitive function in all patient groups.

Conclusions: Our study found differences in cognitive function that aligned with levels of treatment resistance: the greater the degree of treatment resistance, the poorer the cognitive function. Interventions to improve negative and disorganisation symptoms might be effective to enhance the cognitive function and treatment outcomes in schizophrenia.

导言:耐药精神分裂症(TRS)患者约占精神分裂症患者的 30%。在接受氯氮平治疗的TRS患者中,约有一半患者没有表现出有意义的临床反应,即氯氮平耐药。迄今为止,认知功能与治疗反应类别之间的关系尚不完全清楚。本研究评估了按治疗反应分层的亚组的认知表现,我们假设认知障碍会随着治疗耐药性的增加而增加:本研究在新加坡精神卫生研究所进行,研究对象包括健康对照组和精神分裂症患者,他们被分为以下几组:抗精神病药反应型精神分裂症(ARS)、氯氮平反应型TRS(TRS-CR)和氯氮平耐药型TRS(超耐药精神分裂症[UTRS])。认知功能采用认知简短评估短表进行评估。症状采用阳性与阴性综合征量表(PANSS)进行测量。计划进行的统计分析包括对年龄、性别、PANSS评分和抗精神病药物剂量等可能影响认知功能的协变量进行调整:结果:两组患者的整体认知能力存在明显差异:ARS受损程度最小,其次是TRS-CR和UTRS。抗精神病药物剂量、PANSS阴性和混乱/认知因素是所有患者组整体认知功能的重要预测因素:我们的研究发现,认知功能的差异与治疗耐受程度有关:治疗耐受程度越高,认知功能越差。对精神分裂症患者的认知功能和治疗效果进行干预,可能会有效改善患者的阴性症状和精神紊乱症状。
{"title":"Association between treatment resistance and cognitive function in schizophrenia.","authors":"Jiaqian Sun, Jie Yin Yee, Yuen Mei See, Charmaine Tang, Shushan Zheng, Boon Tat Ng, Jimmy Lee","doi":"10.4103/singaporemedj.SMJ-2024-143","DOIUrl":"10.4103/singaporemedj.SMJ-2024-143","url":null,"abstract":"<p><strong>Introduction: </strong>Treatment-resistant schizophrenia (TRS) affects around 30% of individuals with schizophrenia. About half of the patients with TRS who are treated with clozapine do not show a meaningful clinical response, that is, clozapine resistance. To date, the relationship between cognitive function and treatment response categories is not entirely clear. This study evaluated the cognitive performance across subgroups stratified by treatment response, and we hypothesised that cognitive impairment increases with increased treatment resistance.</p><p><strong>Methods: </strong>This study was conducted at the Institute of Mental Health, Singapore, and included healthy controls and people with schizophrenia categorised into these groups: antipsychotic-responsive schizophrenia (ARS), clozapine-responsive TRS (TRS-CR) and clozapine-resistant TRS (ultra-treatment-resistant schizophrenia [UTRS]). Cognitive function was assessed using the Brief Assessment of Cognition-Short Form. Symptoms were measured with the Positive and Negative Syndrome Scale (PANSS). The planned statistical analyses included adjustments for covariates such as age, sex, PANSS scores and antipsychotic dose, which might affect cognitive function.</p><p><strong>Results: </strong>There were significant differences in overall cognitive performance between the groups: ARS had the least impairment, followed by TRS-CR and UTRS. Antipsychotic dose, and PANSS negative and disorganisation/cognitive factors were significant predictors of overall cognitive function in all patient groups.</p><p><strong>Conclusions: </strong>Our study found differences in cognitive function that aligned with levels of treatment resistance: the greater the degree of treatment resistance, the poorer the cognitive function. Interventions to improve negative and disorganisation symptoms might be effective to enhance the cognitive function and treatment outcomes in schizophrenia.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary care approach to first-episode psychosis. 针对首发精神病的初级保健方法。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2022-124
Tabitha Jia Ling Mok, Choon How How, David Choon Liang Teo, Vanessa Wai Ling Mok
{"title":"Primary care approach to first-episode psychosis.","authors":"Tabitha Jia Ling Mok, Choon How How, David Choon Liang Teo, Vanessa Wai Ling Mok","doi":"10.4103/singaporemedj.SMJ-2022-124","DOIUrl":"10.4103/singaporemedj.SMJ-2022-124","url":null,"abstract":"","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive synthesis of mHealth interventions in psychiatry: insights from systematic, scoping, narrative reviews and content analysis. 精神病学中的移动保健干预措施综合综述:从系统、范围界定、叙事回顾和内容分析中获得的启示。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2024-165
Zaakira Shahul Hameed Mahreen, Noor Azziah Zainuldin, Melvyn Weibin Zhang

Introduction: Mobile health (mHealth) technologies, including smartphone apps and wearables, have improved health care by providing innovative solutions for monitoring, education and treatment, particularly in mental health.

Method: This review synthesises findings from a series of reviews on mHealth interventions in psychiatry. Publications were systematically searched in PubMed, MEDLINE, PsycINFO, ScienceDirect, Scopus, Web of Science and Cochrane Library.

Results: Out of 2147 records, 111 studies from 2014 to 2024 focusing on anxiety and depression were included. These studies highlight the effectiveness of mHealth interventions in reducing symptoms through cognitive-behavioural therapy, mindfulness and psychoeducation, benefitting adolescents, perinatal women and marginalised groups. Additionally, mHealth shows promise in managing substance use disorders and severe mental illnesses like schizophrenia, bipolar disorder and psychosis.

Conclusion: Despite positive outcomes, challenges such as data privacy, user engagement and healthcare integration persist. Further robust trials and evidence-based research are needed to validate the efficacy of mHealth technologies.

简介移动医疗(mHealth)技术,包括智能手机应用程序和可穿戴设备,通过提供监测、教育和治疗的创新解决方案改善了医疗保健,尤其是在精神健康方面:本综述综合了一系列有关精神科移动医疗干预措施的综述结果。在 PubMed、MEDLINE、PsycINFO、ScienceDirect、Scopus、Web of Science 和 Cochrane Library 中系统检索了相关文献:结果:在 2147 条记录中,共纳入了 111 项从 2014 年到 2024 年关于焦虑症和抑郁症的研究。这些研究强调了移动医疗干预措施在通过认知行为疗法、正念和心理教育减少症状方面的有效性,青少年、围产期妇女和边缘化群体从中受益。此外,移动保健在控制药物使用障碍和严重精神疾病(如精神分裂症、躁郁症和精神病)方面也大有可为:尽管取得了积极成果,但数据隐私、用户参与和医疗保健整合等挑战依然存在。要验证移动医疗技术的功效,还需要进一步开展强有力的试验和循证研究。
{"title":"Comprehensive synthesis of mHealth interventions in psychiatry: insights from systematic, scoping, narrative reviews and content analysis.","authors":"Zaakira Shahul Hameed Mahreen, Noor Azziah Zainuldin, Melvyn Weibin Zhang","doi":"10.4103/singaporemedj.SMJ-2024-165","DOIUrl":"10.4103/singaporemedj.SMJ-2024-165","url":null,"abstract":"<p><strong>Introduction: </strong>Mobile health (mHealth) technologies, including smartphone apps and wearables, have improved health care by providing innovative solutions for monitoring, education and treatment, particularly in mental health.</p><p><strong>Method: </strong>This review synthesises findings from a series of reviews on mHealth interventions in psychiatry. Publications were systematically searched in PubMed, MEDLINE, PsycINFO, ScienceDirect, Scopus, Web of Science and Cochrane Library.</p><p><strong>Results: </strong>Out of 2147 records, 111 studies from 2014 to 2024 focusing on anxiety and depression were included. These studies highlight the effectiveness of mHealth interventions in reducing symptoms through cognitive-behavioural therapy, mindfulness and psychoeducation, benefitting adolescents, perinatal women and marginalised groups. Additionally, mHealth shows promise in managing substance use disorders and severe mental illnesses like schizophrenia, bipolar disorder and psychosis.</p><p><strong>Conclusion: </strong>Despite positive outcomes, challenges such as data privacy, user engagement and healthcare integration persist. Further robust trials and evidence-based research are needed to validate the efficacy of mHealth technologies.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review. 个性化经颅磁刺激治疗耐药抑郁症、合并焦虑的抑郁症和精神分裂症阴性症状:综述。
Pub Date : 2024-10-01 Epub Date: 2024-10-04 DOI: 10.4103/singaporemedj.SMJ-2024-133
Xiao Wei Tan, Hasvinjit Kaur Gulwant Singh, Jovi Zheng Jie Koh, Rachel Si Yun Tan, Phern Chern Tor

Abstract: Transcranial magnetic stimulation (TMS) is a promising intervention for treatment-resistant psychiatric disorders. However, conventional TMS typically utilises a one-size-fits-all approach when determining stimulation targets. Recent retrospective brain circuit-based analyses using lesion network mapping have suggested that a left dorsal lateral prefrontal cortex target has a higher efficacy for alleviating depression symptoms, a dorsomedial prefrontal cortex target is more effective for anxiety symptoms, and a rostromedial prefrontal cortex target is effective for schizophrenia-associated psychiatric symptoms. Nonetheless, symptom-specific brain circuit targeting has not been tested prospectively. We conducted a narrative review of selected literature to investigate individualised targeting for TMS and discuss potential future directions to elucidate the efficacy of this approach.

摘要:经颅磁刺激(TMS)是一种很有前景的治疗耐药性精神障碍的干预方法。然而,传统的经颅磁刺激在确定刺激目标时通常采用一刀切的方法。最近利用病变网络图进行的基于脑回路的回顾性分析表明,左侧背外侧前额叶皮层靶点对缓解抑郁症状更有效,背内侧前额叶皮层靶点对焦虑症状更有效,而喙内侧前额叶皮层靶点对精神分裂症相关精神症状有效。然而,针对特定症状的脑回路靶向治疗尚未经过前瞻性测试。我们对部分文献进行了叙述性综述,研究了TMS的个体化靶向治疗,并讨论了阐明这种方法疗效的潜在未来方向。
{"title":"Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review.","authors":"Xiao Wei Tan, Hasvinjit Kaur Gulwant Singh, Jovi Zheng Jie Koh, Rachel Si Yun Tan, Phern Chern Tor","doi":"10.4103/singaporemedj.SMJ-2024-133","DOIUrl":"10.4103/singaporemedj.SMJ-2024-133","url":null,"abstract":"<p><strong>Abstract: </strong>Transcranial magnetic stimulation (TMS) is a promising intervention for treatment-resistant psychiatric disorders. However, conventional TMS typically utilises a one-size-fits-all approach when determining stimulation targets. Recent retrospective brain circuit-based analyses using lesion network mapping have suggested that a left dorsal lateral prefrontal cortex target has a higher efficacy for alleviating depression symptoms, a dorsomedial prefrontal cortex target is more effective for anxiety symptoms, and a rostromedial prefrontal cortex target is effective for schizophrenia-associated psychiatric symptoms. Nonetheless, symptom-specific brain circuit targeting has not been tested prospectively. We conducted a narrative review of selected literature to investigate individualised targeting for TMS and discuss potential future directions to elucidate the efficacy of this approach.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding adolescent depression in Singapore: a qualitative study. 了解新加坡的青少年抑郁症:一项定性研究。
Pub Date : 2024-10-01 Epub Date: 2024-01-23 DOI: 10.4103/singaporemedj.SMJ-2022-064
Ngar Yee Poon, Cheryl Bee-Lock Loh

Introduction: This qualitative study aimed to understand the lived experiences of adolescents with depression seeking help in our healthcare system, with the focus on initial symptoms, experience of care and reflection after recovery.

Methods: Semi-structured interviews were conducted with 14 adolescents, aged between 13 and 19 years, who were diagnosed and treated for diagnostic and statistical manual of mental disorders, 5 th edition major depressive disorder and clinically judged to have recovered at the time of recruitment. Data were analysed qualitatively using thematic analysis, with a focus on how the adolescents spoke about their experience of depression.

Results: The findings suggested that our adolescent participants had initially tried managing depression within their own circle, and that thoughts of suicide and self-harm, as well as anhedonia-avolition symptoms were the most challenging to deal with. Recovered participants were observed to express a high degree of empathy towards others going through depression.

Conclusion: This study is the first to have surveyed adolescents in our Asian city-state on multiple aspects of their experience of depression. It allows a wide-ranging description of this condition and has the potential to improve understanding and inform care delivery.

简介:这项定性研究旨在了解患有抑郁症的青少年在医疗系统中寻求帮助时的生活经历,重点是最初的症状、护理经历和康复后的反思:这项定性研究旨在了解患有抑郁症的青少年在医疗系统中寻求帮助的生活经历,重点是初期症状、护理经历和康复后的反思:我们对 14 名青少年进行了半结构化访谈,他们的年龄在 13 至 19 岁之间,在招募时被诊断出患有《精神障碍诊断与统计手册》第 5 版重度抑郁障碍并接受了治疗,而且临床判断他们已经康复。我们采用主题分析法对数据进行了定性分析,重点关注青少年如何讲述他们的抑郁经历:结果:研究结果表明,青少年参与者最初尝试在自己的生活圈子里处理抑郁症,而自杀和自残的想法以及失神-遗忘症状是最难处理的问题。据观察,康复后的参与者对其他抑郁症患者表达了高度的同情:本研究首次对亚洲城市州青少年的抑郁经历进行了多方面的调查。这项研究对抑郁症进行了广泛的描述,有可能加深人们对抑郁症的理解,并为提供护理提供依据。
{"title":"Understanding adolescent depression in Singapore: a qualitative study.","authors":"Ngar Yee Poon, Cheryl Bee-Lock Loh","doi":"10.4103/singaporemedj.SMJ-2022-064","DOIUrl":"10.4103/singaporemedj.SMJ-2022-064","url":null,"abstract":"<p><strong>Introduction: </strong>This qualitative study aimed to understand the lived experiences of adolescents with depression seeking help in our healthcare system, with the focus on initial symptoms, experience of care and reflection after recovery.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 14 adolescents, aged between 13 and 19 years, who were diagnosed and treated for diagnostic and statistical manual of mental disorders, 5 th edition major depressive disorder and clinically judged to have recovered at the time of recruitment. Data were analysed qualitatively using thematic analysis, with a focus on how the adolescents spoke about their experience of depression.</p><p><strong>Results: </strong>The findings suggested that our adolescent participants had initially tried managing depression within their own circle, and that thoughts of suicide and self-harm, as well as anhedonia-avolition symptoms were the most challenging to deal with. Recovered participants were observed to express a high degree of empathy towards others going through depression.</p><p><strong>Conclusion: </strong>This study is the first to have surveyed adolescents in our Asian city-state on multiple aspects of their experience of depression. It allows a wide-ranging description of this condition and has the potential to improve understanding and inform care delivery.</p>","PeriodicalId":94289,"journal":{"name":"Singapore medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Singapore medical journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1