首页 > 最新文献

European heart journal. Imaging methods and practice最新文献

英文 中文
A new protocol for a single-stage combined cardiopulmonary and echocardiography exercise test: a pilot study. 单阶段心肺和超声心动图联合运动测试的新方案:一项试验研究。
Pub Date : 2024-03-21 eCollection Date: 2024-01-01 DOI: 10.1093/ehjimp/qyae021
Dan M Dorobantu, Curtis A Wadey, Ben Berryman, Nurul H Amir, Lynsey Forsythe, A Graham Stuart, Guido E Pieles, Craig A Williams

Aims: The value of cardiopulmonary exercise testing (CPET) and exercise stress echocardiography (ESE) in managing cardiac disease is well known, but no standard CPET-ESE protocol is currently recommended. This pilot study aims to compare feasibility and cardiac function responses between a new high-intensity single-stage combined test (CPET-hiESE) and a standard maximal ESE (smESE).

Methods and results: After screening and maximal CPET, all volunteers (n = 21) underwent three ESE modalities: (i) based on the gas exchange threshold (hiESE-GET, 40% of peak-GET, 6 min), (ii) based on heart rate (HR) (hiESE-HR, 80% of peak HR, 6 min), and (iii) smESE (85% of predicted peak HR for age, 3 min). Speckle tracking echocardiography (STE) and tissue Doppler imaging (TDI) were measured at each step. There was superior image quality and data completeness for the right ventricle strain for both hiESE modalities compared with smESE (71.4 and 76.2 vs. 42.9%, P = 0.07). Left ventricular STE data completeness was similar for all three conditions. Despite systematically higher HR, work rate and levels of exertion in the smESE compared with hiESE, STE and TDI parameters were not systematically different. Concordance correlation coefficients ranged from 0.56 to 0.88, lowest for strain rate parameters and mean difference from -0.34 to 1.53, highest for TDI measurements.

Conclusion: The novel CPET-hiESE protocol allowed for better data completeness, at lower levels of exertion compared with smESE, without systematically different cardiac reserve measurements in healthy participants. This single-stage protocol can be individualized to clinical populations, which would provide practical advantages to standard testing.

目的:心肺运动测试(CPET)和运动负荷超声心动图(ESE)在心脏病治疗中的价值众所周知,但目前尚未推荐标准的 CPET-ESE 方案。本试验研究旨在比较新的高强度单阶段联合测试(CPET-hiESE)和标准最大 ESE(smESE)的可行性和心功能反应:在筛查和最大 CPET 之后,所有志愿者(n = 21)接受了三种 ESE 模式:(i) 基于气体交换阈值(hiESE-GET,峰值-GET 的 40%,6 分钟);(ii) 基于心率(HR)(hiESE-HR,峰值 HR 的 80%,6 分钟);(iii) smESE(年龄预测峰值 HR 的 85%,3 分钟)。每个步骤都测量了斑点追踪超声心动图(STE)和组织多普勒成像(TDI)。与 smESE 相比,两种 hiESE 模式的右心室应变的图像质量和数据完整性都更好(71.4% 和 76.2% 对 42.9%,P = 0.07)。在所有三种情况下,左心室 STE 数据完整性相似。尽管与 hiESE 相比,smESE 的心率、工作率和用力程度明显更高,但 STE 和 TDI 参数并无明显差异。一致性相关系数从 0.56 到 0.88 不等,应变率参数最低,平均差异从 -0.34 到 1.53 不等,TDI 测量最高:结论:与 smESE 相比,新的 CPET-hiESE 方案能在较低的负荷水平下获得更完整的数据,但对健康参与者的心脏储备测量结果并无系统性差异。这种单阶段方案可根据临床人群进行个体化设计,这将为标准测试提供实用优势。
{"title":"A new protocol for a single-stage combined cardiopulmonary and echocardiography exercise test: a pilot study.","authors":"Dan M Dorobantu, Curtis A Wadey, Ben Berryman, Nurul H Amir, Lynsey Forsythe, A Graham Stuart, Guido E Pieles, Craig A Williams","doi":"10.1093/ehjimp/qyae021","DOIUrl":"10.1093/ehjimp/qyae021","url":null,"abstract":"<p><strong>Aims: </strong>The value of cardiopulmonary exercise testing (CPET) and exercise stress echocardiography (ESE) in managing cardiac disease is well known, but no standard CPET-ESE protocol is currently recommended. This pilot study aims to compare feasibility and cardiac function responses between a new high-intensity single-stage combined test (CPET-hiESE) and a standard maximal ESE (smESE).</p><p><strong>Methods and results: </strong>After screening and maximal CPET, all volunteers (<i>n</i> = 21) underwent three ESE modalities: (i) based on the gas exchange threshold (hiESE-GET, 40% of peak-GET, 6 min), (ii) based on heart rate (HR) (hiESE-HR, 80% of peak HR, 6 min), and (iii) smESE (85% of predicted peak HR for age, 3 min). Speckle tracking echocardiography (STE) and tissue Doppler imaging (TDI) were measured at each step. There was superior image quality and data completeness for the right ventricle strain for both hiESE modalities compared with smESE (71.4 and 76.2 vs. 42.9%, <i>P</i> = 0.07). Left ventricular STE data completeness was similar for all three conditions. Despite systematically higher HR, work rate and levels of exertion in the smESE compared with hiESE, STE and TDI parameters were not systematically different. Concordance correlation coefficients ranged from 0.56 to 0.88, lowest for strain rate parameters and mean difference from -0.34 to 1.53, highest for TDI measurements.</p><p><strong>Conclusion: </strong>The novel CPET-hiESE protocol allowed for better data completeness, at lower levels of exertion compared with smESE, without systematically different cardiac reserve measurements in healthy participants. This single-stage protocol can be individualized to clinical populations, which would provide practical advantages to standard testing.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing cardiovascular imaging department efficiency through robust quality systems and effective risk management. 通过健全的质量体系和有效的风险管理,提高心血管造影部门的效率。
Pub Date : 2024-02-16 eCollection Date: 2024-01-01 DOI: 10.1093/ehjimp/qyae012
Roberta Lo Giudice, Alessia Gimelli, Marianna Venditti
{"title":"Enhancing cardiovascular imaging department efficiency through robust quality systems and effective risk management.","authors":"Roberta Lo Giudice, Alessia Gimelli, Marianna Venditti","doi":"10.1093/ehjimp/qyae012","DOIUrl":"10.1093/ehjimp/qyae012","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ST-segment elevation myocardial infarction due to a giant coronary artery aneurysm caused by IgG4-related disease. IgG4相关疾病引起的巨大冠状动脉瘤导致ST段抬高型心肌梗死。
Pub Date : 2024-02-12 eCollection Date: 2024-01-01 DOI: 10.1093/ehjimp/qyae011
Yasuhiro Honda, Kensaku Nishihira, Mitsuhiro Yano, Atsuko Yokota, Yujiro Asada
{"title":"ST-segment elevation myocardial infarction due to a giant coronary artery aneurysm caused by IgG4-related disease.","authors":"Yasuhiro Honda, Kensaku Nishihira, Mitsuhiro Yano, Atsuko Yokota, Yujiro Asada","doi":"10.1093/ehjimp/qyae011","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae011","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning-based computed tomography quantification of left ventricular mass. 基于深度学习的计算机断层扫描左心室质量量化。
Pub Date : 2023-12-08 eCollection Date: 2023-09-01 DOI: 10.1093/ehjimp/qyad043
Amro Sehly, Albert He, Jacob Agris, John Konstantopoulos, Jack Joyner, Julien Flack, Simon Kwok, Benjamin J W Chow, Brian Ko, Michael Ridner, Abdul Rahman Ihdayhid, Girish Dwivedi
{"title":"Deep learning-based computed tomography quantification of left ventricular mass.","authors":"Amro Sehly, Albert He, Jacob Agris, John Konstantopoulos, Jack Joyner, Julien Flack, Simon Kwok, Benjamin J W Chow, Brian Ko, Michael Ridner, Abdul Rahman Ihdayhid, Girish Dwivedi","doi":"10.1093/ehjimp/qyad043","DOIUrl":"10.1093/ehjimp/qyad043","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A systematic review and meta-analysis of transthoracic echocardiogram vs. cardiac magnetic resonance imaging for the detection of left ventricular thrombus. 经胸超声心动图与心脏磁共振成像在检测左心室血栓方面的系统性回顾和荟萃分析。
Pub Date : 2023-12-07 eCollection Date: 2023-09-01 DOI: 10.1093/ehjimp/qyad041
YuZhi Phuah, Ying Xin Tan, Sheref Zaghloul, Sharmaine Sim, Joshua Wong, Saba Usmani, Lily Snell, Karish Thavabalan, Carmen Lucia García-Pérez, Niraj S Kumar, Hannah Glatzel, Reubeen Rashid Ahmad, Luciano Candilio, Jonathan J H Bray, Mahmood Ahmed, Rui Providencia

Transthoracic echocardiography (TTE) is the most commonly used imaging modality to diagnose left ventricular thrombus (LVT), however, cardiac magnetic resonance (CMR) remains the gold standard investigation. A comparison of the diagnostic performance between two modalities is needed to inform guidelines on a diagnostic approach towards LVT. We performed a systematic review and meta-analysis to investigate the diagnostic performance of three methods of TTE (non-contrast, contrast, and apical wall motion scoring) for the detection of LVT compared to CMR as a reference test. Studies comprising 2113 patients investigated for LVT using both TTE and CMR were included in the meta-analysis. For non-contrast TTE, pooled sensitivity and specificity were 47% [95% confidence interval (CI): 32-62%], and 98% (95% CI: 96-99%), respectively. In contrast, TTE pooled sensitivity and specificity values were 58% (95% CI: 46-69%), and 98% (95% CI: 96-99%), respectively. Apical wall motion scoring on non-contrast TTE yielded a sensitivity of 100% [95% CI: 93-100%] and a specificity of 54% (95% CI: 42-65%). The area under the curve (AUC) values from our summary receiver operating characteristic curve (SROC) for non-contrast and contrast TTE were 0.87 and 0.86 respectively, with apical wall motion studies having the highest AUC of 0.93. Despite high specificity, routine contrast and non-contrast TTE are likely to miss a significant number of LVT, making it a suboptimal screening tool. The addition of apical wall motion scoring provides a promising method to reliably identify patients requiring further investigations for LVT, whilst excluding others from unnecessary testing.

经胸超声心动图(TTE)是诊断左心室血栓(LVT)最常用的成像方式,但心脏磁共振(CMR)仍是金标准检查。需要对两种模式的诊断性能进行比较,以便为左心室血栓的诊断方法提供指导。我们进行了一项系统性回顾和荟萃分析,研究了三种 TTE 方法(非对比、对比和心尖壁运动评分)与作为参考检查的 CMR 相比在检测 LVT 方面的诊断性能。荟萃分析纳入了 2113 例同时使用 TTE 和 CMR 检测左心室室间隔缺损的患者。对于非对比 TTE,汇总的敏感性和特异性分别为 47% [95% 置信区间 (CI):32-62%] 和 98% (95% CI:96-99%)。相比之下,TTE 的集合敏感性和特异性分别为 58%(95% 置信区间:46-69%)和 98%(95% 置信区间:96-99%)。非对比 TTE 心尖壁运动评分的敏感性为 100%[95%CI:93-100%],特异性为 54%(95%CI:42-65%)。非对比和对比 TTE 的受体操作特征曲线(SROC)的曲线下面积(AUC)值分别为 0.87 和 0.86,其中心尖壁运动研究的 AUC 值最高,为 0.93。尽管特异性很高,但常规造影剂和非造影剂 TTE 可能会漏诊大量 LVT,使其成为一种不理想的筛查工具。增加心尖壁运动评分提供了一种有前途的方法,既能可靠地识别需要进一步检查左心室造影的患者,又能将其他患者排除在不必要的检查之外。
{"title":"A systematic review and meta-analysis of transthoracic echocardiogram vs. cardiac magnetic resonance imaging for the detection of left ventricular thrombus.","authors":"YuZhi Phuah, Ying Xin Tan, Sheref Zaghloul, Sharmaine Sim, Joshua Wong, Saba Usmani, Lily Snell, Karish Thavabalan, Carmen Lucia García-Pérez, Niraj S Kumar, Hannah Glatzel, Reubeen Rashid Ahmad, Luciano Candilio, Jonathan J H Bray, Mahmood Ahmed, Rui Providencia","doi":"10.1093/ehjimp/qyad041","DOIUrl":"10.1093/ehjimp/qyad041","url":null,"abstract":"<p><p>Transthoracic echocardiography (TTE) is the most commonly used imaging modality to diagnose left ventricular thrombus (LVT), however, cardiac magnetic resonance (CMR) remains the gold standard investigation. A comparison of the diagnostic performance between two modalities is needed to inform guidelines on a diagnostic approach towards LVT. We performed a systematic review and meta-analysis to investigate the diagnostic performance of three methods of TTE (non-contrast, contrast, and apical wall motion scoring) for the detection of LVT compared to CMR as a reference test. Studies comprising 2113 patients investigated for LVT using both TTE and CMR were included in the meta-analysis. For non-contrast TTE, pooled sensitivity and specificity were 47% [95% confidence interval (CI): 32-62%], and 98% (95% CI: 96-99%), respectively. In contrast, TTE pooled sensitivity and specificity values were 58% (95% CI: 46-69%), and 98% (95% CI: 96-99%), respectively. Apical wall motion scoring on non-contrast TTE yielded a sensitivity of 100% [95% CI: 93-100%] and a specificity of 54% (95% CI: 42-65%). The area under the curve (AUC) values from our summary receiver operating characteristic curve (SROC) for non-contrast and contrast TTE were 0.87 and 0.86 respectively, with apical wall motion studies having the highest AUC of 0.93. Despite high specificity, routine contrast and non-contrast TTE are likely to miss a significant number of LVT, making it a suboptimal screening tool. The addition of apical wall motion scoring provides a promising method to reliably identify patients requiring further investigations for LVT, whilst excluding others from unnecessary testing.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11240154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-time guidance by deep learning of experienced operators to improve the standardization of echocardiographic acquisitions. 通过对经验丰富的操作员进行深度学习来提供实时指导,从而提高超声心动图采集的标准化程度。
Pub Date : 2023-11-27 eCollection Date: 2023-09-01 DOI: 10.1093/ehjimp/qyad040
Sigbjorn Sabo, David Pasdeloup, Hakon Neergaard Pettersen, Erik Smistad, Andreas Østvik, Sindre Hellum Olaisen, Stian Bergseng Stølen, Bjørnar Leangen Grenne, Espen Holte, Lasse Lovstakken, Havard Dalen

Aims: Impaired standardization of echocardiograms may increase inter-operator variability. This study aimed to determine whether the real-time guidance of experienced sonographers by deep learning (DL) could improve the standardization of apical recordings.

Methods and results: Patients (n = 88) in sinus rhythm referred for echocardiography were included. All participants underwent three examinations, whereof two were performed by sonographers and the third by cardiologists. In the first study period (Period 1), the sonographers were instructed to provide echocardiograms for the analyses of the left ventricular function. Subsequently, after brief training, the DL guidance was used in Period 2 by the sonographer performing the second examination. View standardization was quantified retrospectively by a human expert as the primary endpoint and the DL algorithm as the secondary endpoint. All recordings were scored in rotation and tilt both separately and combined and were categorized as standardized or non-standardized. Sonographers using DL guidance had more standardized acquisitions for the combination of rotation and tilt than sonographers without guidance in both periods (all P ≤ 0.05) when evaluated by the human expert and DL [except for the apical two-chamber (A2C) view by DL evaluation]. When rotation and tilt were analysed individually, A2C and apical long-axis rotation and A2C tilt were significantly improved, and the others were numerically improved when evaluated by the echocardiography expert. Furthermore, all, except for A2C rotation, were significantly improved when evaluated by DL (P < 0.01).

Conclusion: Real-time guidance by DL improved the standardization of echocardiographic acquisitions by experienced sonographers. Future studies should evaluate the impact with respect to variability of measurements and when used by less-experienced operators.

Clinicaltrialsgov identifier: NCT04580095.

目的:超声心动图的标准化程度不高可能会增加操作者之间的差异性。本研究旨在确定通过深度学习(DL)对经验丰富的超声技师进行实时指导是否能提高心尖记录的标准化程度:研究纳入了窦性心律患者(n = 88)进行超声心动图检查。所有参与者均接受了三次检查,其中两次由超声技师进行,第三次由心脏病专家进行。在第一个研究阶段(第一阶段),超声技师接受指导,为分析左心室功能提供超声心动图。随后,经过简单培训后,超声技师在第二阶段进行第二次检查时使用 DL 指导。视图标准化由人类专家进行回顾性量化,作为主要终点,DL 算法作为次要终点。所有记录均按旋转和倾斜度分别或合并评分,并分为标准化和非标准化两类。在由人类专家和 DL 进行评估时(除心尖两腔(A2C)视图由 DL 评估外),使用 DL 引导的超声技师在两个时期内获得的旋转和倾斜组合标准化程度均高于未使用引导的超声技师(所有 P 均小于 0.05)。在对旋转和倾斜进行单独分析时,A2C 和心尖长轴旋转以及 A2C 倾斜均有显著改善,而在由超声心动图专家进行评估时,其他均有数值上的改善。此外,除 A2C 旋转外,其他均在 DL 评估时有明显改善(P < 0.01):结论:DL 的实时指导提高了经验丰富的超声技师超声心动图采集的标准化程度。未来的研究应评估测量的可变性和经验不足的操作者使用时的影响:NCT04580095。
{"title":"Real-time guidance by deep learning of experienced operators to improve the standardization of echocardiographic acquisitions.","authors":"Sigbjorn Sabo, David Pasdeloup, Hakon Neergaard Pettersen, Erik Smistad, Andreas Østvik, Sindre Hellum Olaisen, Stian Bergseng Stølen, Bjørnar Leangen Grenne, Espen Holte, Lasse Lovstakken, Havard Dalen","doi":"10.1093/ehjimp/qyad040","DOIUrl":"10.1093/ehjimp/qyad040","url":null,"abstract":"<p><strong>Aims: </strong>Impaired standardization of echocardiograms may increase inter-operator variability. This study aimed to determine whether the real-time guidance of experienced sonographers by deep learning (DL) could improve the standardization of apical recordings.</p><p><strong>Methods and results: </strong>Patients (<i>n</i> = 88) in sinus rhythm referred for echocardiography were included. All participants underwent three examinations, whereof two were performed by sonographers and the third by cardiologists. In the first study period (Period 1), the sonographers were instructed to provide echocardiograms for the analyses of the left ventricular function. Subsequently, after brief training, the DL guidance was used in Period 2 by the sonographer performing the second examination. View standardization was quantified retrospectively by a human expert as the primary endpoint and the DL algorithm as the secondary endpoint. All recordings were scored in rotation and tilt both separately and combined and were categorized as standardized or non-standardized. Sonographers using DL guidance had more standardized acquisitions for the combination of rotation and tilt than sonographers without guidance in both periods (all <i>P</i> ≤ 0.05) when evaluated by the human expert and DL [except for the apical two-chamber (A2C) view by DL evaluation]. When rotation and tilt were analysed individually, A2C and apical long-axis rotation and A2C tilt were significantly improved, and the others were numerically improved when evaluated by the echocardiography expert. Furthermore, all, except for A2C rotation, were significantly improved when evaluated by DL (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Real-time guidance by DL improved the standardization of echocardiographic acquisitions by experienced sonographers. Future studies should evaluate the impact with respect to variability of measurements and when used by less-experienced operators.</p><p><strong>Clinicaltrialsgov identifier: </strong>NCT04580095.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual cause of reversible complete heart block: Right sinus of Valsalva rupture and compressive pseudo- aneurysm 可逆性完全性心脏传导阻滞的不寻常原因:右Valsalva窦破裂和压缩性假性动脉瘤
Pub Date : 2023-11-08 DOI: 10.1093/ehjimp/qyad038
Amélie Marang, Marc Bonnet, Thomas Rees, Jonathan Bentz, Sébastien Gerelli
{"title":"An unusual cause of reversible complete heart block: Right sinus of Valsalva rupture and compressive pseudo- aneurysm","authors":"Amélie Marang, Marc Bonnet, Thomas Rees, Jonathan Bentz, Sébastien Gerelli","doi":"10.1093/ehjimp/qyad038","DOIUrl":"https://doi.org/10.1093/ehjimp/qyad038","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135430058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epicardial adipose tissue in patients with systemic sclerosis 系统性硬化症患者的心外膜脂肪组织
Pub Date : 2023-11-03 DOI: 10.1093/ehjimp/qyad037
Xu Wang, Steele C Butcher, Rinchyenkhand Myagmardorj, Sophie IE Liem, Victoria Delgado, Jeroen J Bax, Jeska K De Vries-Bouwstra, Nina Ajmone Marsan
Abstract Aims Epicardial adipose tissue (EAT) has emerged as a mediator between systemic inflammatory disorders and cardiovascular disease, and may therefore play a role in the pathophysiology of cardiac involvement in systemic sclerosis (SSc). The aim of this study was to assess the correlation between EAT and left ventricular (LV) function, and to determine the prognostic value of EAT in patients with SSc. Methods and results Consecutive patients with SSc who underwent non-contrast thorax computed tomography and echocardiography were included. EAT mass was quantified using dedicated software. The study endpoint was all-cause mortality. A total of 230 SSc patients [age 53±15 years, 14% male] were included. The median value of EAT mass was 67g (IQR: 45-101g). Patients with increased EAT mass (≥67g) showed more impaired LV diastolic function as compared to patients with less EAT mass (&lt;67g), and even after adjusting for age and comorbidities, EAT mass was independently associated with LV diastolic function parameters. During a median follow-up of 8 years, 42 deaths occurred. Kaplan-Meier analysis showed that patients with increased EAT mass had higher all-cause mortality rate as compared to patients with less EAT mass (29% vs 7 %; P&lt;0.001). In the multivariable analysis, EAT was independently associated with all-cause mortality after adjusting for important covariates (HR:1.006; 95%CI:1.001-1.010). Conclusion In patients with SSc, EAT is independently associated with LV diastolic dysfunction and higher mortality rate.
摘要目的心外膜脂肪组织(EAT)已成为全身性炎症性疾病和心血管疾病之间的中介,因此可能在系统性硬化症(SSc)中心脏受累的病理生理学中发挥作用。本研究的目的是评估EAT与左心室(LV)功能的相关性,并确定EAT在SSc患者中的预后价值。方法和结果对连续行胸部ct和超声心动图检查的SSc患者进行分析。使用专用软件定量EAT质量。研究终点为全因死亡率。共纳入230例SSc患者,年龄53±15岁,男性占14%。EAT质量中位数为67g (IQR: 45-101g)。与EAT质量较低(<67g)的患者相比,EAT质量增加(≥67g)的患者左室舒张功能受损更严重,即使在调整年龄和合共病后,EAT质量与左室舒张功能参数独立相关。在平均8年的随访期间,发生了42例死亡。Kaplan-Meier分析显示,与EAT体积较小的患者相比,EAT体积增大的患者具有更高的全因死亡率(29% vs 7%;P&肝移植;0.001)。在多变量分析中,在调整重要协变量后,EAT与全因死亡率独立相关(HR:1.006;95%置信区间:1.001—-1.010)。结论在SSc患者中,EAT与左室舒张功能障碍和较高的死亡率独立相关。
{"title":"Epicardial adipose tissue in patients with systemic sclerosis","authors":"Xu Wang, Steele C Butcher, Rinchyenkhand Myagmardorj, Sophie IE Liem, Victoria Delgado, Jeroen J Bax, Jeska K De Vries-Bouwstra, Nina Ajmone Marsan","doi":"10.1093/ehjimp/qyad037","DOIUrl":"https://doi.org/10.1093/ehjimp/qyad037","url":null,"abstract":"Abstract Aims Epicardial adipose tissue (EAT) has emerged as a mediator between systemic inflammatory disorders and cardiovascular disease, and may therefore play a role in the pathophysiology of cardiac involvement in systemic sclerosis (SSc). The aim of this study was to assess the correlation between EAT and left ventricular (LV) function, and to determine the prognostic value of EAT in patients with SSc. Methods and results Consecutive patients with SSc who underwent non-contrast thorax computed tomography and echocardiography were included. EAT mass was quantified using dedicated software. The study endpoint was all-cause mortality. A total of 230 SSc patients [age 53±15 years, 14% male] were included. The median value of EAT mass was 67g (IQR: 45-101g). Patients with increased EAT mass (≥67g) showed more impaired LV diastolic function as compared to patients with less EAT mass (&amp;lt;67g), and even after adjusting for age and comorbidities, EAT mass was independently associated with LV diastolic function parameters. During a median follow-up of 8 years, 42 deaths occurred. Kaplan-Meier analysis showed that patients with increased EAT mass had higher all-cause mortality rate as compared to patients with less EAT mass (29% vs 7 %; P&amp;lt;0.001). In the multivariable analysis, EAT was independently associated with all-cause mortality after adjusting for important covariates (HR:1.006; 95%CI:1.001-1.010). Conclusion In patients with SSc, EAT is independently associated with LV diastolic dysfunction and higher mortality rate.","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135874668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-invasive left ventricular pressure-volume loops from cardiovascular magnetic resonance imaging and brachial blood pressure: validation using pressure catheter measurements. 无创左心室压力-容积环心血管磁共振成像和肱血压:使用压力导管测量验证。
Pub Date : 2023-10-25 eCollection Date: 2023-09-01 DOI: 10.1093/ehjimp/qyad035
Per M Arvidsson, Peregrine G Green, William D Watson, Mayooran Shanmuganathan, Einar Heiberg, Giovanni Luigi De Maria, Håkan Arheden, Neil Herring, Oliver J Rider

Aims: Left ventricular (LV) pressure-volume (PV) loops provide gold-standard physiological information but require invasive measurements of ventricular intracavity pressure, limiting clinical and research applications. A non-invasive method for the computation of PV loops from magnetic resonance imaging and brachial cuff blood pressure has recently been proposed. Here we evaluated the fidelity of the non-invasive PV algorithm against invasive LV pressures in humans.

Methods and results: Four heart failure patients with EF < 35% and LV dyssynchrony underwent cardiovascular magnetic resonance (CMR) imaging and subsequent LV catheterization with sequential administration of two different intravenous metabolic substrate infusions (insulin/dextrose and lipid emulsion), producing eight datasets at different haemodynamic states. Pressure-volume loops were computed from CMR volumes combined with (i) a time-varying elastance function scaled to brachial blood pressure and temporally stretched to match volume data, or (ii) invasive pressures averaged from 19 to 30 sampled beats. Method comparison was conducted using linear regression and Bland-Altman analysis. Non-invasively derived PV loop parameters demonstrated high correlation and low bias when compared to invasive data for stroke work (R2 = 0.96, P < 0.0001, bias 4.6%), potential energy (R2 = 0.83, P = 0.001, bias 1.5%), end-systolic pressure-volume relationship (R2 = 0.89, P = 0.0004, bias 5.8%), ventricular efficiency (R2 = 0.98, P < 0.0001, bias 0.8%), arterial elastance (R2 = 0.88, P = 0.0006, bias -8.0%), mean external power (R2 = 0.92, P = 0.0002, bias 4.4%), and energy per ejected volume (R2 = 0.89, P = 0.0001, bias 3.7%). Variations in estimated end-diastolic pressure did not significantly affect results (P > 0.05 for all). Intraobserver analysis after one year demonstrated 0.9-3.4% bias for LV volumetry and 0.2-5.4% for PV loop-derived parameters.

Conclusion: Pressure-volume loops can be precisely and accurately computed from CMR imaging and brachial cuff blood pressure in humans.

目的:左心室(LV)压力-容积(PV)环路提供了金标准的生理信息,但需要侵入性测量心室腔内压力,限制了临床和研究应用。最近提出了一种从磁共振成像和臂袖血压计算PV环的无创方法。在这里,我们评估了非侵入性PV算法对人类侵入性左室压力的保真度。方法和结果:4例EF < 35%且左室不同步的心力衰竭患者行心血管磁共振(CMR)成像,随后行左室导管置管,并顺序给予两种不同的静脉代谢底物输注(胰岛素/葡萄糖和脂质乳),产生不同血流动力学状态的8个数据集。根据CMR容积计算压力-容积循环,并结合(i)按肱血压缩放的时变弹性函数,并暂时拉伸以匹配容积数据,或(ii) 19至30次采样心跳的平均侵入性压力。方法采用线性回归和Bland-Altman分析进行比较。方法推导出光伏循环参数表现出高度的相关性和低偏差相比,中风的入侵数据工作(R2 = 0.96, P < 0.0001,偏差4.6%),势能(R2 = 0.83, P = 0.001,偏差1.5%),收缩末期压力-容积关系(R2 = 0.89, P = 0.0004,偏差5.8%)、心室效率(R2 = 0.98, P < 0.0001,偏差0.8%),动脉倒电容(R2 = 0.88, P = 0.0006,偏差-8.0%),意思是外部力量(R2 = 0.92, P = 0.0002,偏差4.4%),和每喷射体积能量(R2 = 0.89, P = 0.0001,偏差3.7%)。估计舒张末期压的变化对结果没有显著影响(P < 0.05)。一年后的观察者内部分析显示,左室容积法的偏差为0.9-3.4%,PV环路衍生参数的偏差为0.2-5.4%。结论:通过CMR成像和肱袖带血压可以精确计算出压力-容积环。
{"title":"Non-invasive left ventricular pressure-volume loops from cardiovascular magnetic resonance imaging and brachial blood pressure: validation using pressure catheter measurements.","authors":"Per M Arvidsson, Peregrine G Green, William D Watson, Mayooran Shanmuganathan, Einar Heiberg, Giovanni Luigi De Maria, Håkan Arheden, Neil Herring, Oliver J Rider","doi":"10.1093/ehjimp/qyad035","DOIUrl":"10.1093/ehjimp/qyad035","url":null,"abstract":"<p><strong>Aims: </strong>Left ventricular (LV) pressure-volume (PV) loops provide gold-standard physiological information but require invasive measurements of ventricular intracavity pressure, limiting clinical and research applications. A non-invasive method for the computation of PV loops from magnetic resonance imaging and brachial cuff blood pressure has recently been proposed. Here we evaluated the fidelity of the non-invasive PV algorithm against invasive LV pressures in humans.</p><p><strong>Methods and results: </strong>Four heart failure patients with EF < 35% and LV dyssynchrony underwent cardiovascular magnetic resonance (CMR) imaging and subsequent LV catheterization with sequential administration of two different intravenous metabolic substrate infusions (insulin/dextrose and lipid emulsion), producing eight datasets at different haemodynamic states. Pressure-volume loops were computed from CMR volumes combined with (i) a time-varying elastance function scaled to brachial blood pressure and temporally stretched to match volume data, or (ii) invasive pressures averaged from 19 to 30 sampled beats. Method comparison was conducted using linear regression and Bland-Altman analysis. Non-invasively derived PV loop parameters demonstrated high correlation and low bias when compared to invasive data for stroke work (R<sup>2</sup> = 0.96, <i>P</i> < 0.0001, bias 4.6%), potential energy (R<sup>2</sup> = 0.83, <i>P</i> = 0.001, bias 1.5%), end-systolic pressure-volume relationship (R<sup>2</sup> = 0.89, <i>P</i> = 0.0004, bias 5.8%), ventricular efficiency (R<sup>2</sup> = 0.98, <i>P</i> < 0.0001, bias 0.8%), arterial elastance (R<sup>2</sup> = 0.88, <i>P</i> = 0.0006, bias -8.0%), mean external power (R<sup>2</sup> = 0.92, <i>P</i> = 0.0002, bias 4.4%), and energy per ejected volume (R<sup>2</sup> = 0.89, <i>P</i> = 0.0001, bias 3.7%). Variations in estimated end-diastolic pressure did not significantly affect results (<i>P</i> > 0.05 for all). Intraobserver analysis after one year demonstrated 0.9-3.4% bias for LV volumetry and 0.2-5.4% for PV loop-derived parameters.</p><p><strong>Conclusion: </strong>Pressure-volume loops can be precisely and accurately computed from CMR imaging and brachial cuff blood pressure in humans.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter aortic valve replacement in quadricuspid aortic valve: the crucial role of three-dimensional simulation in risk assessment 经导管四尖瓣主动脉瓣置换术:三维模拟在风险评估中的关键作用
Pub Date : 2023-10-12 DOI: 10.1093/ehjimp/qyad032
Yusuke Oba, Hiroshi Funayama, Masafumi Sato, Hisaya Kobayashi, Kenji Harada, Mamoru Arakawa, Koji Kawahito, Kazuomi Kario
{"title":"Transcatheter aortic valve replacement in quadricuspid aortic valve: the crucial role of three-dimensional simulation in risk assessment","authors":"Yusuke Oba, Hiroshi Funayama, Masafumi Sato, Hisaya Kobayashi, Kenji Harada, Mamoru Arakawa, Koji Kawahito, Kazuomi Kario","doi":"10.1093/ehjimp/qyad032","DOIUrl":"https://doi.org/10.1093/ehjimp/qyad032","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136015714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European heart journal. Imaging methods and practice
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1