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Differential effects of heat-not-burn, electronic, and conventional cigarettes on endothelial glycocalyx. 加热不燃烧香烟、电子香烟和传统香烟对内皮糖萼的不同影响。
Pub Date : 2023-07-07 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad008
Ignatios Ikonomidis, Konstantinos Katogiannis, Kallirhoe Kourea, Gavriela Kostelli, George Pavlidis, John Thymis, Eleni Katsanaki, Eirini Maratou, Vaia Lambadiari
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引用次数: 0
Fully automatic estimation of global left ventricular systolic function using deep learning in transoesophageal echocardiography. 在经食道超声心动图中使用深度学习全自动估测左心室整体收缩功能
Pub Date : 2023-07-04 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad007
Erik Andreas Rye Berg, Anders Austlid Taskén, Trym Nordal, Bjørnar Grenne, Torvald Espeland, Idar Kirkeby-Garstad, Håvard Dalen, Espen Holte, Stian Stølen, Svend Aakhus, Gabriel Kiss

Aims: To improve monitoring of cardiac function during major surgery and intensive care, we have developed a method for fully automatic estimation of mitral annular plane systolic excursion (auto-MAPSE) using deep learning in transoesophageal echocardiography (TOE). The aim of this study was a clinical validation of auto-MAPSE in patients with heart disease.

Methods and results: TOE recordings were collected from 185 consecutive patients without selection on image quality. Deep-learning-based auto-MAPSE was trained and optimized from 105 patient recordings. We assessed auto-MAPSE feasibility, and agreement and inter-rater reliability with manual reference in 80 patients with and without electrocardiogram (ECG) tracings. Mean processing time for auto-MAPSE was 0.3 s per cardiac cycle/view. Overall feasibility was >90% for manual MAPSE and ECG-enabled auto-MAPSE and 82% for ECG-disabled auto-MAPSE. Feasibility in at least two walls was ≥95% for all methods. Compared with manual reference, bias [95% limits of agreement (LoA)] was -0.5 [-4.0, 3.1] mm for ECG-enabled auto-MAPSE and -0.2 [-4.2, 3.6] mm for ECG-disabled auto-MAPSE. Intra-class correlation coefficient (ICC) for consistency was 0.90 and 0.88, respectively. Manual inter-observer bias [95% LoA] was -0.9 [-4.7, 3.0] mm, and ICC was 0.86.

Conclusion: Auto-MAPSE was fast and highly feasible. Inter-rater reliability between auto-MAPSE and manual reference was good. Agreement between auto-MAPSE and manual reference did not differ from manual inter-observer agreement. As the principal advantages of deep-learning-based assessment are speed and reproducibility, auto-MAPSE has the potential to improve real-time monitoring of left ventricular function. This should be investigated in relevant clinical settings.

目的:为了改善大手术和重症监护期间的心脏功能监测,我们开发了一种在经食道超声心动图(TOE)中使用深度学习全自动估算二尖瓣环平面收缩期偏移(auto-MAPSE)的方法。本研究的目的是在心脏病患者中对自动 MAPSE 进行临床验证:收集了 185 名连续患者的 TOE 记录,未对图像质量进行选择。基于深度学习的自动 MAPSE 从 105 份患者记录中进行了训练和优化。我们评估了自动 MAPSE 的可行性,以及与 80 名有和没有心电图(ECG)记录的患者的人工参考的一致性和评分者之间的可靠性。自动 MAPSE 的平均处理时间为每个心动周期/视图 0.3 秒。手动 MAPSE 和支持心电图的自动 MAPSE 的总体可行性大于 90%,支持心电图的自动 MAPSE 的总体可行性大于 82%。所有方法在至少两壁的可行性均≥95%。与人工参考相比,启用心电图的自动 MAPSE 的偏差[95% 一致性限值 (LoA)] 为 -0.5 [-4.0, 3.1] 毫米,启用心电图的自动 MAPSE 为 -0.2 [-4.2, 3.6] 毫米。一致性的类内相关系数 (ICC) 分别为 0.90 和 0.88。人工观察者间偏差[95% LoA]为-0.9 [-4.7, 3.0]毫米,ICC 为 0.86:结论:Auto-MAPSE 快速且非常可行。自动 MAPSE 与人工参考之间的评分者间可靠性良好。自动 MAPSE 与人工参考之间的一致性与人工观察者之间的一致性没有差异。由于基于深度学习的评估的主要优势在于速度和可重复性,因此自动 MAPSE 有可能改善左心室功能的实时监测。这一点应在相关临床环境中加以研究。
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引用次数: 0
Prognostic impact of cardiac resynchronization therapy guided by phase analysis: a CZT study. 相位分析指导下的心脏再同步化疗法的预后影响:CZT 研究。
Pub Date : 2023-06-19 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad004
Riccardo Liga, Umberto Startari, Davide Spatafora, Erica Michelotti, Alessia Gimelli

Aims: To evaluate whether phase analysis imaging may predict treatment response and long-term prognosis after cardiac resynchronization therapy (CRT).

Methods and results: Sixty-nine patients underwent myocardial perfusion imaging followed by CRT. Patients with ischaemic heart disease and non-ischaemic cardiomyopathy (NICM) were identified. Left ventricular (LV) mechanical dyssynchrony (LVMD) was assessed at phase analysis and the region of the latest mechanical activation was identified. LV pacing lead position was considered 'concordant' when located in the region of the latest mechanical activation, and 'discordant' otherwise. The '6 months post-CRT'/'baseline' ratio of LV ejection fraction was computed as a measure of CRT response. LVMD was revealed in 47/69 patients, 27 of whom (57%) had a concordant LV lead implantation. Only concordant pacing was associated with LV functional improvement (ejection fraction ratio: 1.28 ± 0.25 vs. 1.11 ± 0.32 in discordant stimulation, P = 0.028). However, this relationship persisted only in patients with NICM (P < 0.001), while it disappeared in those with ischaemic heart disease (P = NS). Twenty-eight events occurred during 30 ± 21 months follow-up. While discordant LV lead location was the major predictor of unfavourable prognosis (hazard ratio 3.29, 95% confidence interval 1.25-8.72; P = 0.016), this relationship was confirmed only in patients with NICM.

Conclusions: Phase analysis of myocardial perfusion imaging may guide CRT implantation, identifying patients who would most likely benefit from this procedure.

目的:评估相位分析成像能否预测心脏再同步化治疗(CRT)后的治疗反应和长期预后:69名患者接受了心肌灌注成像,随后进行了CRT治疗。确定了缺血性心脏病和非缺血性心肌病(NICM)患者。相位分析评估了左心室机械不同步(LVMD),并确定了最新机械激活区域。如果左心室起搏导联位置位于最新机械激活区域,则视为 "一致",否则视为 "不一致"。计算 "CRT 术后 6 个月"/"基线 "左心室射血分数比值,作为衡量 CRT 反应的指标。47/69 例患者显示出 LVMD,其中 27 例(57%)植入了一致的左心室导联。只有一致起搏与左心室功能改善有关(射血分数比:1.28 ± 0.25 vs. 不一致刺激为 1.11 ± 0.32,P = 0.028)。然而,这种关系仅在 NICM 患者中持续存在(P < 0.001),而在缺血性心脏病患者中则消失了(P = NS)。在 30 ± 21 个月的随访期间,共发生了 28 起事件。虽然左心室导联位置不一致是预后不良的主要预测因素(危险比为3.29,95%置信区间为1.25-8.72;P = 0.016),但这种关系仅在NICM患者中得到证实:结论:心肌灌注成像的相位分析可为 CRT 植入术提供指导,识别出最有可能从该手术中获益的患者。
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引用次数: 0
Towards standardization of positron emission testing with computed tomography myocardial perfusion volumes and left ventricular ejection fraction: comparison with cardiac MRI. 正电子发射检测与计算机断层扫描心肌灌注容量和左心室射血分数的标准化:与心脏磁共振成像的比较。
Pub Date : 2023-06-16 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad006
Tiffany A Dong, Bryan Q Abadie, Erika Hutt Centeno, Christine L Jellis, Paul C Cremer, Wael A Jaber

Gated positron emission testing with computed tomography (PET-CT) yields left ventricular (LV) volume analysis along with perfusion analysis. The correlation between PET-CT volumes and cardiac magnetic resonance imaging (CMR) volumes remains unknown. Understanding of the accuracy of these volumes and ejection fractions (EF) by PET is clinically relevant, particularly in the sarcoid population where patients receive initial diagnostic CMR and then are followed by PET for inflammation. 89 patients undergoing cardiac sarcoidosis evaluation with both rest PET-CT and CMR within approximately 1 year were identified at Cleveland Clinic from 2011 to 2021. LV volumes and EF were collected. Linear regression and Bland-Altman analyses were performed. Mean PET-CT derived left ventricular ejection fraction (LVEF) was 46 ± 16% with mean LV end diastolic volume (LVEDV) of 127 ± 60 mL and mean LV end systolic volume (LVESV) of 75 ± 54 mL. Mean CMR-derived LVEF was 47 ± 15% with mean LVEDV of 189 ± 61 mL and mean LVESV of 106 ± 60 mL. Pearson correlation coefficient with standard measurements was 0.85 for EF, 0.80 for LVEDV, and 0.86 for LVESV. In our cohort, there is an excellent correlation of LVEF between PET-CT and CMR with a mean difference of 1.1% and a good correlation of volumes between these two imaging modalities. This has potential clinical implications when judging LVEF qualifications for medical and device therapies although future larger validation cohorts are warranted.

计算机断层扫描选通正电子发射检测(PET-CT)可进行左心室(LV)容积分析和灌注分析。PET-CT 容量与心脏磁共振成像(CMR)容量之间的相关性仍然未知。通过 PET 了解这些容积和射血分数 (EF) 的准确性与临床息息相关,尤其是在肉样瘤人群中,患者在接受最初的 CMR 诊断后,还要接受 PET 的炎症随访。克利夫兰诊所在 2011 年至 2021 年期间确定了 89 名在约 1 年内接受静息 PET-CT 和 CMR 心脏肉瘤病评估的患者。收集了左心室容积和EF。进行了线性回归和 Bland-Altman 分析。PET-CT 得出的左心室射血分数(LVEF)平均为 46 ± 16%,左心室舒张末期容积(LVEDV)平均为 127 ± 60 mL,左心室收缩末期容积(LVESV)平均为 75 ± 54 mL。CMR 导出的平均 LVEF 为 47 ± 15%,平均 LVEDV 为 189 ± 61 mL,平均 LVESV 为 106 ± 60 mL。EF 与标准测量值的皮尔逊相关系数为 0.85,LVEDV 为 0.80,LVESV 为 0.86。在我们的队列中,PET-CT 和 CMR 之间 LVEF 的相关性非常好,平均差异为 1.1%,这两种成像模式之间的容积相关性也很好。这对于判断 LVEF 是否符合医疗和设备疗法的要求具有潜在的临床意义,但未来还需要更大规模的验证队列。
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引用次数: 0
Pericardial late gadolinium enhancement and time to recurrence: a substudy from RHAPSODY, a phase 3 clinical trial of rilonacept in recurrent pericarditis. 心包晚期钆增强与复发时间:RHAPSODY 的一项子研究,Rilonacept 治疗复发性心包炎的 3 期临床试验。
Pub Date : 2023-05-26 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad003
Paul C Cremer, David Lin, Sushil A Luis, John Petersen, Antonio Abbate, Christine L Jellis, Debbie Kwon, Antonio Brucato, Fang Fang, Antonella Insalaco, Martin LeWinter, Basil S Lewis, Liangxing Zou, Stephen J Nicholls, Allan L Klein, Massimo Imazio, John F Paolini

Aims: In this protocol-predefined substudy of the RHAPSODY trial, the primary aim was to assess whether pericardial late gadolinium enhancement (LGE) was associated with time to pericarditis recurrence.

Methods and results: RHAPSODY was a Phase 3 double-blind, placebo-controlled, randomized-withdrawal trial that demonstrated the efficacy of rilonacept in recurrent pericarditis (RP). Patients with a history of multiple RP and an active recurrence were enrolled and had the option to participate in a cardiac magnetic resonance (CMR) imaging substudy. CMRs were interpreted by a blinded independent core laboratory with prespecified criteria to define pericardial LGE. Compared to patients with trace or mild pericardial LGE (n = 9), patients with moderate or severe pericardial LGE (n = 16) generally had a higher number of recurrent episodes per year (5.3 vs. 3.9) and a higher mean CRP level (3.6 vs. 1.1 mg/dL). Overall, 10/14 (71.4%) who received a placebo had a recurrence compared to 0/11 (0%) who received rilonacept. In patients randomized to placebo who had moderate or severe pericardial LGE, the median time to recurrence was 4.2 weeks compared to 10.7 weeks in patients who had trace or mild pericardial LGE. At the conclusion of the event-driven randomized-withdrawal period, among patients receiving a placebo, 5/7 (71.4%) with trace or mild pericardial LGE and 5/7 (71.4%) with moderate or severe pericardial LGE had a recurrence.

Conclusions: Among patients with multiple RP, these preliminary findings support the concept of pericardial LGE as an imaging biomarker that may inform the duration of treatment and risk of recurrence with cessation of therapy and larger studies should be considered.

Clinicaltrialsgov identifier: NCT03737110.

目的:在这项RHAPSODY试验的方案预设子研究中,主要目的是评估心包晚期钆增强(LGE)是否与心包炎复发时间相关:RHAPSODY是一项3期双盲、安慰剂对照、随机撤销试验,该试验证明了利龙赛普对复发性心包炎(RP)的疗效。有多次 RP 病史和活动性复发的患者被纳入试验,并可选择参加心脏磁共振 (CMR) 成像子研究。CMR由盲法独立核心实验室根据预先规定的心包LGE定义标准进行解读。与微量或轻度心包LGE患者(9人)相比,中度或重度心包LGE患者(16人)每年的复发次数更高(5.3次对3.9次),平均CRP水平更高(3.6毫克/分升对1.1毫克/分升)。总体而言,10/14(71.4%)名接受安慰剂治疗的患者复发,而0/11(0%)名接受利龙赛普治疗的患者复发。在随机接受安慰剂治疗的中度或重度心包LGE患者中,复发的中位时间为4.2周,而微量或轻度心包LGE患者的复发时间为10.7周。在事件驱动的随机退出期结束时,接受安慰剂治疗的患者中,5/7(71.4%)有微量或轻度心包LGE,5/7(71.4%)有中度或重度心包LGE的患者复发:在多发性 RP 患者中,这些初步研究结果支持将心包 LGE 作为成像生物标志物的概念,该标志物可为治疗持续时间和停止治疗后的复发风险提供信息,应考虑进行更大规模的研究:NCT03737110。
{"title":"Pericardial late gadolinium enhancement and time to recurrence: a substudy from RHAPSODY, a phase 3 clinical trial of rilonacept in recurrent pericarditis.","authors":"Paul C Cremer, David Lin, Sushil A Luis, John Petersen, Antonio Abbate, Christine L Jellis, Debbie Kwon, Antonio Brucato, Fang Fang, Antonella Insalaco, Martin LeWinter, Basil S Lewis, Liangxing Zou, Stephen J Nicholls, Allan L Klein, Massimo Imazio, John F Paolini","doi":"10.1093/ehjimp/qyad003","DOIUrl":"10.1093/ehjimp/qyad003","url":null,"abstract":"<p><strong>Aims: </strong>In this protocol-predefined substudy of the RHAPSODY trial, the primary aim was to assess whether pericardial late gadolinium enhancement (LGE) was associated with time to pericarditis recurrence.</p><p><strong>Methods and results: </strong>RHAPSODY was a Phase 3 double-blind, placebo-controlled, randomized-withdrawal trial that demonstrated the efficacy of rilonacept in recurrent pericarditis (RP). Patients with a history of multiple RP and an active recurrence were enrolled and had the option to participate in a cardiac magnetic resonance (CMR) imaging substudy. CMRs were interpreted by a blinded independent core laboratory with prespecified criteria to define pericardial LGE. Compared to patients with trace or mild pericardial LGE (<i>n</i> = 9), patients with moderate or severe pericardial LGE (<i>n</i> = 16) generally had a higher number of recurrent episodes per year (5.3 vs. 3.9) and a higher mean CRP level (3.6 vs. 1.1 mg/dL). Overall, 10/14 (71.4%) who received a placebo had a recurrence compared to 0/11 (0%) who received rilonacept. In patients randomized to placebo who had moderate or severe pericardial LGE, the median time to recurrence was 4.2 weeks compared to 10.7 weeks in patients who had trace or mild pericardial LGE. At the conclusion of the event-driven randomized-withdrawal period, among patients receiving a placebo, 5/7 (71.4%) with trace or mild pericardial LGE and 5/7 (71.4%) with moderate or severe pericardial LGE had a recurrence.</p><p><strong>Conclusions: </strong>Among patients with multiple RP, these preliminary findings support the concept of pericardial LGE as an imaging biomarker that may inform the duration of treatment and risk of recurrence with cessation of therapy and larger studies should be considered.</p><p><strong>Clinicaltrialsgov identifier: </strong>NCT03737110.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11240150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84233887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of endosonography in cardiology: case series and literature review. 内窥镜在心脏病学中的作用:病例系列和文献综述。
Pub Date : 2023-05-17 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad002
Abdelrahman Elhakim, Kawther Karkour, Philip Sauter, Michael Rode, Mohamed Elhakim, Peter W Radke, Mohammed Saad

Aims: Endosonography (EUS) is the diagnostic tool with the highest resolution for the local staging of gastrointestinal tumours and, due to the detailed visualization of the wall layers, is recommended in current guidelines for cancer management. In addition, an endoscope has an ultrasound tip design and balloon insufflation control design, and a 120° bending mechanism to deflect the endoscope tip. These advantages could be beneficial and valuable while investigating the cardiovascular structures during routine gastrointestinal procedures using this diagnostic tool.

Methods and results: We present six cases of incidentally diagnosed cardiac pathologies (pulmonary thromboembolism of the main pulmonary artery, patent foramen oval with right to left shunt under Valsalva, left atrial appendage thrombus, aortic dissection, moderate aortic valve stenosis, mitral and aortic valve endocarditis) during routine gastrointestinal endosonographic procedures. These diagnoses influenced changes in management strategies in four cases.

Conclusion: The introduction of EUS in cardiovascular medicine allows for a real-time high-resolution assessment of cardiovascular structures and allows early detection of silent cardiac pathologies during routine gastrointestinal procedures. It is the diagnostic tool with the highest resolution for accurate definition of variable gastrointestinal anatomy. Thus, help for accurate definitions of cardiovascular anatomy and pathology, which could influence optimal management strategies with improved safety, efficacy, and economic outcomes.

目的:内窥镜成像(EUS)是对胃肠道肿瘤进行局部分期的分辨率最高的诊断工具,由于能详细观察肿瘤壁层,因此被推荐用于目前的癌症治疗指南中。此外,内窥镜还具有超声波尖端设计和球囊充气控制设计,以及可使内窥镜尖端偏转 120° 的弯曲机制。在使用这种诊断工具进行常规胃肠道手术时,这些优势在检查心血管结构时可能是有益和有价值的:我们介绍了六例在常规胃肠道内窥镜检查过程中意外诊断出的心脏病变(主肺动脉肺血栓栓塞、卵圆孔伴Valsalva下右向左分流、左心房阑尾血栓、主动脉夹层、主动脉瓣中度狭窄、二尖瓣和主动脉瓣心内膜炎)。这些诊断改变了四例病例的治疗策略:结论:将 EUS 引入心血管内科可对心血管结构进行实时高分辨率评估,并可在常规胃肠道手术中及早发现无声的心脏病变。它是分辨率最高的诊断工具,可准确定义可变的胃肠道解剖结构。因此,有助于准确定义心血管解剖和病理,从而影响最佳管理策略,提高安全性、有效性和经济效益。
{"title":"The role of endosonography in cardiology: case series and literature review.","authors":"Abdelrahman Elhakim, Kawther Karkour, Philip Sauter, Michael Rode, Mohamed Elhakim, Peter W Radke, Mohammed Saad","doi":"10.1093/ehjimp/qyad002","DOIUrl":"10.1093/ehjimp/qyad002","url":null,"abstract":"<p><strong>Aims: </strong>Endosonography (EUS) is the diagnostic tool with the highest resolution for the local staging of gastrointestinal tumours and, due to the detailed visualization of the wall layers, is recommended in current guidelines for cancer management. In addition, an endoscope has an ultrasound tip design and balloon insufflation control design, and a 120° bending mechanism to deflect the endoscope tip. These advantages could be beneficial and valuable while investigating the cardiovascular structures during routine gastrointestinal procedures using this diagnostic tool.</p><p><strong>Methods and results: </strong>We present six cases of incidentally diagnosed cardiac pathologies (pulmonary thromboembolism of the main pulmonary artery, patent foramen oval with right to left shunt under Valsalva, left atrial appendage thrombus, aortic dissection, moderate aortic valve stenosis, mitral and aortic valve endocarditis) during routine gastrointestinal endosonographic procedures. These diagnoses influenced changes in management strategies in four cases.</p><p><strong>Conclusion: </strong>The introduction of EUS in cardiovascular medicine allows for a real-time high-resolution assessment of cardiovascular structures and allows early detection of silent cardiac pathologies during routine gastrointestinal procedures. It is the diagnostic tool with the highest resolution for accurate definition of variable gastrointestinal anatomy. Thus, help for accurate definitions of cardiovascular anatomy and pathology, which could influence optimal management strategies with improved safety, efficacy, and economic outcomes.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11249961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89941219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
European Heart Journal-Imaging Methods and Practice (EHJ-IMP): new perspectives, new partnerships, more IMPact. 欧洲心脏杂志-成像方法与实践(EHJ-IMP):新视角、新合作、更多 IMPact。
Pub Date : 2023-05-04 eCollection Date: 2023-05-01 DOI: 10.1093/ehjimp/qyad001
Alessia Gimelli
{"title":"European Heart Journal-Imaging Methods and Practice (EHJ-IMP): new perspectives, new partnerships, more IMPact.","authors":"Alessia Gimelli","doi":"10.1093/ehjimp/qyad001","DOIUrl":"10.1093/ehjimp/qyad001","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11195686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89753956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical appraisal of a non-invasive model to derive pulmonary capillary wedge pressure from cardiac magnetic resonance in heart failure patients: insights from a large Portuguese Observational Study 对心衰患者通过心脏磁共振获得肺毛细血管楔压的无创模型进行批判性评价:来自葡萄牙大型观察性研究的见解
Pub Date : 2023-05-01 DOI: 10.1093/ehjimp/qyad017
Sérgio Maltês, Mariana Sousa Paiva, Rita Reis Santos, Bruno M L Rocha, Gonçalo J L Cunha, Cláudia Silva, Sara Guerreiro, Pedro Freitas, João Abecasis, António M Ferreira
{"title":"Critical appraisal of a non-invasive model to derive pulmonary capillary wedge pressure from cardiac magnetic resonance in heart failure patients: insights from a large Portuguese Observational Study","authors":"Sérgio Maltês, Mariana Sousa Paiva, Rita Reis Santos, Bruno M L Rocha, Gonçalo J L Cunha, Cláudia Silva, Sara Guerreiro, Pedro Freitas, João Abecasis, António M Ferreira","doi":"10.1093/ehjimp/qyad017","DOIUrl":"https://doi.org/10.1093/ehjimp/qyad017","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135517228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of temporary mechanical circulatory support devices in cath-lab and cardiac intensive care unit 导管室和心脏重症监护病房临时机械循环支持装置的管理
Pub Date : 2023-05-01 DOI: 10.1093/ehjimp/qyad011
Federico Fortuni, Filippo Zilio, Gianmarco Iannopollo, Giuseppe Ciliberti, Paolo Trambaiolo, Laura Ceriello, Francesca Musella, Pietro Scicchitano, Stefano Albani, Stefania Angela Di Fusco, Michele Massimo Gulizia, Domenico Gabrielli, Fabrizio Oliva, Furio Colivicchi
Abstract Different temporary mechanical circulatory support (tMCS) devices are available and can be used to maintain end-organ perfusion while reducing cardiac work and myocardial oxygen demand. tMCS can provide support to the right ventricle, left ventricle, or both, and its use can be considered in emergency situations such as cardiogenic shock or in elective procedures such as high-risk percutaneous coronary intervention to prevent haemodynamic deterioration. Invasive and, most importantly, non-invasive haemodynamic parameters should be taken into account when choosing the type of tMCS device and its initiation and weaning timing, determining the need for a device upgrade, and screening for complications. In this context, ultrasound tools, specifically echocardiography, can provide important data. This review aims to provide a description of the different tMCS devices, the invasive and non-invasive tools and parameters to guide their management, and their advantages and drawbacks.
临时机械循环支持(tMCS)装置可用于维持终末器官灌注,同时减少心脏功和心肌需氧量。tMCS可以为右心室、左心室或两者提供支持,可以考虑在紧急情况下(如心源性休克)或选择性手术(如高风险经皮冠状动脉介入治疗)中使用,以防止血流动力学恶化。在选择tMCS设备的类型及其启动和脱机时间、确定设备升级的需要以及筛查并发症时,应考虑有创性和最重要的非创性血流动力学参数。在这种情况下,超声工具,特别是超声心动图,可以提供重要的数据。本文旨在介绍不同的tMCS设备,侵入性和非侵入性的工具和参数来指导其管理,以及它们的优缺点。
{"title":"Management of temporary mechanical circulatory support devices in cath-lab and cardiac intensive care unit","authors":"Federico Fortuni, Filippo Zilio, Gianmarco Iannopollo, Giuseppe Ciliberti, Paolo Trambaiolo, Laura Ceriello, Francesca Musella, Pietro Scicchitano, Stefano Albani, Stefania Angela Di Fusco, Michele Massimo Gulizia, Domenico Gabrielli, Fabrizio Oliva, Furio Colivicchi","doi":"10.1093/ehjimp/qyad011","DOIUrl":"https://doi.org/10.1093/ehjimp/qyad011","url":null,"abstract":"Abstract Different temporary mechanical circulatory support (tMCS) devices are available and can be used to maintain end-organ perfusion while reducing cardiac work and myocardial oxygen demand. tMCS can provide support to the right ventricle, left ventricle, or both, and its use can be considered in emergency situations such as cardiogenic shock or in elective procedures such as high-risk percutaneous coronary intervention to prevent haemodynamic deterioration. Invasive and, most importantly, non-invasive haemodynamic parameters should be taken into account when choosing the type of tMCS device and its initiation and weaning timing, determining the need for a device upgrade, and screening for complications. In this context, ultrasound tools, specifically echocardiography, can provide important data. This review aims to provide a description of the different tMCS devices, the invasive and non-invasive tools and parameters to guide their management, and their advantages and drawbacks.","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135466111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to: a practical guide to cardiac conduction devices on chest radiograph 如何:胸片上心脏传导装置的实用指南
Pub Date : 2023-05-01 DOI: 10.1093/ehjimp/qyad009
Kyaw Soe Tun, Donnchadh Reidy, Una Buckley
Abstract With the increasing number of cardiac conduction devices (CCDs) insertions with various complexities in recent decades, it is crucial for clinicians (especially internal medicine residents and cardiologists) to have an up-to-date review of the current devices on chest radiograph. Chest X-ray remains the most cost-effective and accessible imaging modality to assess the device position and its associated complications, not only immediately after insertion but also during the follow-up visit as outpatient. Various types of CCDs such as permanent pacemaker, implantable cardioverter defibrillator, and cardiac resynchronization therapy (CRT, CRT with defibrillation or pacing) with their appearances on chest radiograph and possible complications with a step-by-step guide to how to assess are discussed in this article.
近几十年来,随着各种复杂的心脏传导装置(CCDs)插入数量的增加,对临床医生(特别是内科住院医生和心脏病专家)来说,对当前胸片上的心脏传导装置进行最新的回顾是至关重要的。胸部x线仍然是评估装置位置及其相关并发症的最具成本效益和最容易获得的成像方式,不仅在插入后立即进行,而且在门诊随访期间进行。本文讨论了各种类型的ccd,如永久性起搏器、植入式心律转复除颤器和心脏再同步治疗(CRT, CRT与除颤或起搏),以及它们在胸片上的表现和可能的并发症,并给出了如何评估的逐步指南。
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引用次数: 0
期刊
European heart journal. Imaging methods and practice
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