Pub Date : 2024-05-30eCollection Date: 2024-01-01DOI: 10.1099/acmi.0.000762.v3
Ömür Baysal, David J Studholme, Catherine Jimenez-Quiros, Mahmut Tör
Many Gram-positive spore-forming rhizobacteria of the genus Bacillus show potential as biocontrol biopesticides that promise improved sustainability and ecological safety in agriculture. Here, we present a draft-quality genome sequence for Bacillus velezensis EU07, which shows growth-promotion in tomato plants and biocontrol against Fusarium head blight. We found that the genome of EU07 is almost identical to that of the commercially used strain QST713, but identified 46 single-nucleotide differences that distinguish these strains from each other. The availability of this genome sequence will facilitate future efforts to unravel the genetic and molecular basis for EU07's beneficial properties.
{"title":"Genome sequence of the plant-growth-promoting bacterium Bacillus velezensis EU07.","authors":"Ömür Baysal, David J Studholme, Catherine Jimenez-Quiros, Mahmut Tör","doi":"10.1099/acmi.0.000762.v3","DOIUrl":"10.1099/acmi.0.000762.v3","url":null,"abstract":"<p><p>Many Gram-positive spore-forming rhizobacteria of the genus <i>Bacillus</i> show potential as biocontrol biopesticides that promise improved sustainability and ecological safety in agriculture. Here, we present a draft-quality genome sequence for <i>Bacillus velezensis</i> EU07, which shows growth-promotion in tomato plants and biocontrol against <i>Fusarium</i> head blight. We found that the genome of EU07 is almost identical to that of the commercially used strain QST713, but identified 46 single-nucleotide differences that distinguish these strains from each other. The availability of this genome sequence will facilitate future efforts to unravel the genetic and molecular basis for EU07's beneficial properties.</p>","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"6 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-28eCollection Date: 2024-01-01DOI: 10.1099/acmi.0.000794.v3
Fatima Zahra Adil, Elmostafa Benaissa, Yassine Ben Lahlou, Leila Laamara, Fatna Bssaibis, Adil Maleb, Mariama Chadli, Mostafa Elouennass
Appendicitis, typically caused by appendiceal lumen obstruction, is a prevalent abdominal surgical emergency worldwide. While most cases involve Enterobacterales, Haemophilus influenzae, primarily known for upper respiratory infections, is infrequently associated with gastrointestinal infections. This article presents an exceptional case of acute appendicitis caused by both Haemophilus influenza and Enterobacter cloacae in a 15-year-old child, highlighting the significance of recognizing uncommon pathogens in appendicitis and emphasizing the necessity for thorough microbiological investigations to refine diagnostic approaches.
{"title":"Exceptional association of two species of bacteria causing acute appendicitis: Haemophilus influenzae and Enterobacter cloacae.","authors":"Fatima Zahra Adil, Elmostafa Benaissa, Yassine Ben Lahlou, Leila Laamara, Fatna Bssaibis, Adil Maleb, Mariama Chadli, Mostafa Elouennass","doi":"10.1099/acmi.0.000794.v3","DOIUrl":"10.1099/acmi.0.000794.v3","url":null,"abstract":"<p><p>Appendicitis, typically caused by appendiceal lumen obstruction, is a prevalent abdominal surgical emergency worldwide. While most cases involve <i>Enterobacterales, Haemophilus influenzae</i>, primarily known for upper respiratory infections, is infrequently associated with gastrointestinal infections. This article presents an exceptional case of acute appendicitis caused by both <i>Haemophilus influenza</i> and <i>Enterobacter cloacae</i> in a 15-year-old child, highlighting the significance of recognizing uncommon pathogens in appendicitis and emphasizing the necessity for thorough microbiological investigations to refine diagnostic approaches.</p>","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"6 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-22eCollection Date: 2024-01-01DOI: 10.1099/acmi.0.000843
Wafaa Achache, Jean Louis Mege, Mustapha Fellag, Michel Drancourt
[This corrects the article DOI: 10.1099/acmi.0.000471.v3.].
[此处更正了文章 DOI：10.1099/acmi.0.000471.v3.]。
{"title":"Corrigendum: The Enterococcus secretome inhibits the growth of Mycobacterium tuberculosis complex mycobacteria.","authors":"Wafaa Achache, Jean Louis Mege, Mustapha Fellag, Michel Drancourt","doi":"10.1099/acmi.0.000843","DOIUrl":"10.1099/acmi.0.000843","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1099/acmi.0.000471.v3.].</p>","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"6 5","pages":"000843"},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11170129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141319423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Older adults are more severely affected by infections caused by drug-resistant bacteria including Methicillin-Resistant Staphylococcus aureus (MRSA). We aimed to identify the MRSA colonization rates and associated factors among older adults aged more than 65-years-old. Among the 309 recruited, 152 (49.2 %) were males. Self-collected nasal swabs were used to isolate Staphylococcus aureus and MRSA with routine microbiological methods. Staphylococcus aureus was isolated from 36 (11.7 %) participants while 11 (3.6 %) were colonized with MRSA. We identified a significant association between the male sex and MRSA colonization (P=0.028, Chi-square test). However, this needs careful interpretation given the smaller number of outcome events. Other factors studied had no statistically significant association with MRSA colonization.
{"title":"Brief Report: Nasal colonization with Staphylococcus aureus and methicillin resistant Staphylococcus aureus among community-dwelling older adults with comorbidities seeking follow-up medical care in Central Sri Lanka.","authors":"Ifaaz Iqbal, Zeenath Sabri, Adithya Illangasinghe, Ashini Isurindi, Rashmi Jayakodi, Wasana Jayasekara, Kaveesha Jayarathna, Nonduni Jayasinghe, Mekhala Ishani, Ishan Jayasekara, Nelum Handapangoda, Dilrukshi Menike, Rasadanie Dissanayake, Asela Ekanayake, Veranja Liyanapathirana","doi":"10.1099/acmi.0.000724.v3","DOIUrl":"10.1099/acmi.0.000724.v3","url":null,"abstract":"<p><p>Older adults are more severely affected by infections caused by drug-resistant bacteria including Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA). We aimed to identify the MRSA colonization rates and associated factors among older adults aged more than 65-years-old. Among the 309 recruited, 152 (49.2 %) were males. Self-collected nasal swabs were used to isolate <i>Staphylococcus aureus</i> and MRSA with routine microbiological methods. <i>Staphylococcus aureus</i> was isolated from 36 (11.7 %) participants while 11 (3.6 %) were colonized with MRSA. We identified a significant association between the male sex and MRSA colonization (<i>P</i>=0.028, Chi-square test). However, this needs careful interpretation given the smaller number of outcome events. Other factors studied had no statistically significant association with MRSA colonization.</p>","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"6 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-10DOI: 10.1099/acmi.0.000768.v3
Sadao Aoki, Hiroko Yahara, Ryoma Nakao, Osamu Tsuzukibashi, K. Yahara
To isolate specific bacteria from samples constituting the microbiota, it is essential to employ selective media that suppress the growth of resident bacteria other than specific target bacteria. Selective media for clinically important Actinomyces (including Schaalia, which was previously taxonomically classified as part of the genus Actinomyces) have been limited because they have been designed for a limited range of species within the genus and require ingredients which are difficult to prepare and handle. This study aimed to develop a selective medium [referred to as Actinomyces and Schaalia Selective Medium (ASSM)] for the isolation of a broad range of Actinomyces and Schaalia species from samples mixed with resident bacteria. The composition of ASSM includes yeast extract, agar, brain heart infusion (BHI), levofloxacin (LVFX), fosfomycin (FOM), colistin (CL) and metronidazole (MNZ). Evaluation of the medium using 24 swab samples serially collected from the roots of the teeth of a healthy individual for whom metagenome sequencing data of a saliva sample are publicly available revealed that ASSM adjusted to concentrations of LVFX 0.5 mg l−1, FOM 5 mg l−1, CL 1 mg l−1 and MNZ 2 mg l−1 and cultured anaerobically at 35 °C for 7 days enabled the isolation of Actinomyces species from 37.5 % of the samples. The inclusion of CL and MNZ in ASSM can also be useful for samples harbouring other bacterial species. The selective isolation medium is expected to contribute to studies investigating the relationship between these bacteria and their pathogenesis or disease.
{"title":"Development of selective isolation media for detecting the genera Actinomyces and Schaalia from oral specimens containing indigenous bacteria","authors":"Sadao Aoki, Hiroko Yahara, Ryoma Nakao, Osamu Tsuzukibashi, K. Yahara","doi":"10.1099/acmi.0.000768.v3","DOIUrl":"https://doi.org/10.1099/acmi.0.000768.v3","url":null,"abstract":"To isolate specific bacteria from samples constituting the microbiota, it is essential to employ selective media that suppress the growth of resident bacteria other than specific target bacteria. Selective media for clinically important Actinomyces (including Schaalia, which was previously taxonomically classified as part of the genus Actinomyces) have been limited because they have been designed for a limited range of species within the genus and require ingredients which are difficult to prepare and handle. This study aimed to develop a selective medium [referred to as Actinomyces and Schaalia Selective Medium (ASSM)] for the isolation of a broad range of Actinomyces and Schaalia species from samples mixed with resident bacteria. The composition of ASSM includes yeast extract, agar, brain heart infusion (BHI), levofloxacin (LVFX), fosfomycin (FOM), colistin (CL) and metronidazole (MNZ). Evaluation of the medium using 24 swab samples serially collected from the roots of the teeth of a healthy individual for whom metagenome sequencing data of a saliva sample are publicly available revealed that ASSM adjusted to concentrations of LVFX 0.5 mg l−1, FOM 5 mg l−1, CL 1 mg l−1 and MNZ 2 mg l−1 and cultured anaerobically at 35 °C for 7 days enabled the isolation of Actinomyces species from 37.5 % of the samples. The inclusion of CL and MNZ in ASSM can also be useful for samples harbouring other bacterial species. The selective isolation medium is expected to contribute to studies investigating the relationship between these bacteria and their pathogenesis or disease.","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140993469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-09DOI: 10.1099/acmi.0.000625.v4
Kevin Herold, Ayana Ruffin, Jennifer C. Chmura, Anna J Dellomo, Elana S. Ehrlich
KSHV viral FLICE inhibitory protein (vFLIP) is a potent activator of NF-κB signalling and an inhibitor of apoptosis and autophagy. Inhibition of vFLIP function and NF-κB signalling promotes lytic reactivation. Here we provide evidence for a novel function of vFLIP through inhibition of the deubiquitinating (DUB) activity of the negative regulator, A20. We demonstrate direct interaction of vFLIP with Itch and A20 and provide evidence for subsequent loss of A20 DUB activity. Our results provide further insight into the function of vFLIP in the regulation of NF-κB signalling.
{"title":"Kaposi’s sarcoma herpesvirus viral FLICE inhibitory protein modulates A20 deubiquitinase activity","authors":"Kevin Herold, Ayana Ruffin, Jennifer C. Chmura, Anna J Dellomo, Elana S. Ehrlich","doi":"10.1099/acmi.0.000625.v4","DOIUrl":"https://doi.org/10.1099/acmi.0.000625.v4","url":null,"abstract":"KSHV viral FLICE inhibitory protein (vFLIP) is a potent activator of NF-κB signalling and an inhibitor of apoptosis and autophagy. Inhibition of vFLIP function and NF-κB signalling promotes lytic reactivation. Here we provide evidence for a novel function of vFLIP through inhibition of the deubiquitinating (DUB) activity of the negative regulator, A20. We demonstrate direct interaction of vFLIP with Itch and A20 and provide evidence for subsequent loss of A20 DUB activity. Our results provide further insight into the function of vFLIP in the regulation of NF-κB signalling.","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1099/acmi.0.000719.v3
Seemal Aslam, Salma Abbas, S. Nizamuddin, Muhammad Shehbaz, Azra Parveen, Faisal Sultan, Aun Raza
Introduction. Enteric fever is a significant health concern in endemic countries. While extensive research has been conducted to understand its presentation and outcomes in non-cancer patients, limited data exist on its impact on cancer patients. This descriptive study aims to investigate the clinical presentation and outcome in cancer patients. Methodology. This retrospective observational study analysed 90 adult cancer patients from a single centre in Pakistan from January 2017 to December 2022. Inclusion criteria involved documented blood culture infections with Salmonella typhi or paratyphi A, B, or C. We examined clinical presentation, laboratory parameters, antimicrobial resistance, complications, and outcomes. Additionally, we explored the effects of chemotherapy, comorbidities, type of malignancy, and patient age on complications and mortality. Results. Salmonella typhi was the most prevalent organism (72.2 %), followed by Salmonella paratyphi A (22.2 %) and B (5.5 %). Variably-resistant isolates constituted 51.5 %, multi-drug resistant (MDR) isolates accounted for 20 %, extensively drug-resistant (XDR) for 14.4 % and ESBL-producers for 15.5 %, of all enteric fever infections. Enteric fever-associated complications were observed in 21.1 % of cases. Chemotherapy in the preceding month did not affect mortality, nor did age, gender, or malignancy type. However, comorbidities were statistically significant for mortality (p-value 0.03). A total of 8.8 % of patients required ICU care, and the all-cause 30 day mortality rate was 13.3 % Conclusion. Enteric fever remains prevalent in our geographical region. Unlike non-typhoidal Salmonella (NTS), enteric fever does not behave differently in an immunocompromised population, including cancer patients.
{"title":"Clinical presentation and outcome of enteric fever in adult patients with cancer: a perspective from Pakistan","authors":"Seemal Aslam, Salma Abbas, S. Nizamuddin, Muhammad Shehbaz, Azra Parveen, Faisal Sultan, Aun Raza","doi":"10.1099/acmi.0.000719.v3","DOIUrl":"https://doi.org/10.1099/acmi.0.000719.v3","url":null,"abstract":"\u0000 Introduction. Enteric fever is a significant health concern in endemic countries. While extensive research has been conducted to understand its presentation and outcomes in non-cancer patients, limited data exist on its impact on cancer patients. This descriptive study aims to investigate the clinical presentation and outcome in cancer patients.\u0000 \u0000 Methodology. This retrospective observational study analysed 90 adult cancer patients from a single centre in Pakistan from January 2017 to December 2022. Inclusion criteria involved documented blood culture infections with Salmonella typhi or paratyphi A, B, or C. We examined clinical presentation, laboratory parameters, antimicrobial resistance, complications, and outcomes. Additionally, we explored the effects of chemotherapy, comorbidities, type of malignancy, and patient age on complications and mortality.\u0000 \u0000 Results.\u0000 Salmonella typhi was the most prevalent organism (72.2 %), followed by Salmonella paratyphi A (22.2 %) and B (5.5 %). Variably-resistant isolates constituted 51.5 %, multi-drug resistant (MDR) isolates accounted for 20 %, extensively drug-resistant (XDR) for 14.4 % and ESBL-producers for 15.5 %, of all enteric fever infections. Enteric fever-associated complications were observed in 21.1 % of cases. Chemotherapy in the preceding month did not affect mortality, nor did age, gender, or malignancy type. However, comorbidities were statistically significant for mortality (p-value 0.03). A total of 8.8 % of patients required ICU care, and the all-cause 30 day mortality rate was 13.3 %\u0000 \u0000 Conclusion. Enteric fever remains prevalent in our geographical region. Unlike non-typhoidal Salmonella (NTS), enteric fever does not behave differently in an immunocompromised population, including cancer patients.","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"54 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1099/acmi.0.000755.v3
Inmaculada García-Romero, Rubén de Dios, Francisca Reyes-Ramírez
The sphingomonads encompass a diverse group of bacteria within the family Sphingomonadaceae, with the presence of sphingolipids on their cell surface instead of lipopolysaccharide as their main common feature. They are particularly interesting for bioremediation purposes due to their ability to degrade or metabolise a variety of recalcitrant organic pollutants. However, research and development on their full bioremediation potential has been hampered because of the limited number of tools available to investigate and modify their genome. Here, we present a markerless genome editing method for Sphingopyxis granuli TFA, which can be further optimised for other sphingomonads. This procedure is based on a double recombination triggered by a DNA double-strand break in the chromosome. The strength of this protocol lies in forcing the second recombination rather than favouring it by pressing a counterselection marker, thus avoiding laborious restreaking or passaging screenings. Additionally, we introduce a modification with respect to the original protocol to increase the efficiency of the screening after the first recombination event. We show this procedure step by step and compare our modified method with respect to the original one by deleting ecfG2, the master regulator of the general stress response in S. granuli TFA. This adds to the genetic tool repertoire that can be applied to sphingomonads and stands as an efficient option for fast genome editing of this bacterial group.
鞘氨醇单胞菌是鞘氨醇单胞菌科（Sphingomonadaceae）中的一个多样化细菌群，其主要共同特征是细胞表面存在鞘氨醇脂而不是脂多糖。由于它们能够降解或代谢各种难降解的有机污染物，因此在生物修复方面特别有意义。然而，由于可用于研究和修改其基因组的工具数量有限，对其全部生物修复潜力的研究和开发一直受到阻碍。在这里，我们介绍了一种针对颗粒鞘氨醇 TFA 的无标记基因组编辑方法，该方法可进一步优化用于其他鞘氨醇单胞菌。该方法基于染色体中 DNA 双链断裂引发的双重组。该方案的优势在于通过按下反选标记来强制进行第二次重组，而不是偏向于第二次重组，从而避免了费力的重组或传代筛选。此外，我们还对原始方案进行了修改，以提高第一次重组后的筛选效率。我们逐步展示了这一过程，并比较了我们与原始方法的不同之处，即删除了ecfG2，它是颗粒细胞TFA中一般应激反应的主调控因子。这增加了可应用于鞘氨醇单胞菌的遗传工具库，是对该细菌群进行快速基因组编辑的有效选择。
{"title":"An improved genome editing system for Sphingomonadaceae","authors":"Inmaculada García-Romero, Rubén de Dios, Francisca Reyes-Ramírez","doi":"10.1099/acmi.0.000755.v3","DOIUrl":"https://doi.org/10.1099/acmi.0.000755.v3","url":null,"abstract":"The sphingomonads encompass a diverse group of bacteria within the family Sphingomonadaceae, with the presence of sphingolipids on their cell surface instead of lipopolysaccharide as their main common feature. They are particularly interesting for bioremediation purposes due to their ability to degrade or metabolise a variety of recalcitrant organic pollutants. However, research and development on their full bioremediation potential has been hampered because of the limited number of tools available to investigate and modify their genome. Here, we present a markerless genome editing method for Sphingopyxis granuli TFA, which can be further optimised for other sphingomonads. This procedure is based on a double recombination triggered by a DNA double-strand break in the chromosome. The strength of this protocol lies in forcing the second recombination rather than favouring it by pressing a counterselection marker, thus avoiding laborious restreaking or passaging screenings. Additionally, we introduce a modification with respect to the original protocol to increase the efficiency of the screening after the first recombination event. We show this procedure step by step and compare our modified method with respect to the original one by deleting ecfG2, the master regulator of the general stress response in S. granuli TFA. This adds to the genetic tool repertoire that can be applied to sphingomonads and stands as an efficient option for fast genome editing of this bacterial group.","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1099/acmi.0.000753.v3
Leila Laamara, E. Benaissa, Amine Achemlal, Amal Bounakhla, F. Bssaibis, Y. Benlahlou, Adil Maleb, Mariama Chadli, Mostafa Elouennass
Tuberculosis is an infectious disease that most often affects the lungs, caused by human-to-human transmission of Mycobacterium tuberculosis. Peritoneal tuberculosis is an extra-pulmonary form of the disease that usually manifests as an ascitic syndrome, with or without fever, in a context of altered general condition, often in endemic areas. The diagnosis of peritoneal tuberculosis is not always easy, as the clinical signs are often insidious and unspecific. We report a case of peritoneal tuberculosis in an 18-year-old female, who had presented for 10 days with a progressive increase in abdominal volume associated with vomiting and diarrhoea.
{"title":"Peritoneal tuberculosis, an underestimated diagnosis: a case report","authors":"Leila Laamara, E. Benaissa, Amine Achemlal, Amal Bounakhla, F. Bssaibis, Y. Benlahlou, Adil Maleb, Mariama Chadli, Mostafa Elouennass","doi":"10.1099/acmi.0.000753.v3","DOIUrl":"https://doi.org/10.1099/acmi.0.000753.v3","url":null,"abstract":"Tuberculosis is an infectious disease that most often affects the lungs, caused by human-to-human transmission of Mycobacterium tuberculosis. Peritoneal tuberculosis is an extra-pulmonary form of the disease that usually manifests as an ascitic syndrome, with or without fever, in a context of altered general condition, often in endemic areas. The diagnosis of peritoneal tuberculosis is not always easy, as the clinical signs are often insidious and unspecific. We report a case of peritoneal tuberculosis in an 18-year-old female, who had presented for 10 days with a progressive increase in abdominal volume associated with vomiting and diarrhoea.","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"1 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141138533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01DOI: 10.1099/acmi.0.000774.v4
S. Salavati Schmitz, Jorge Perez-Accino Salgado, Laura Glendinning
Microbiota of healthy dogs demonstrate significant changes in specific bacterial groups in response to supplementation with resistant starch (but not psyllium or methylcellulose) in this randomized cross-over trial.
{"title":"Microbiota of healthy dogs demonstrate a significant decrease in richness and changes in specific bacterial groups in response to supplementation with resistant starch, but not psyllium or methylcellulose, in a randomized cross-over trial","authors":"S. Salavati Schmitz, Jorge Perez-Accino Salgado, Laura Glendinning","doi":"10.1099/acmi.0.000774.v4","DOIUrl":"https://doi.org/10.1099/acmi.0.000774.v4","url":null,"abstract":"\u0000 Microbiota of healthy dogs demonstrate significant changes in specific bacterial groups in response to supplementation with resistant starch (but not psyllium or methylcellulose) in this randomized cross-over trial.\u0000 \u0000 \u0000","PeriodicalId":94366,"journal":{"name":"Access microbiology","volume":"47 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141030326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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