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Julie Makani: leveraging innovation to tackle sickle cell disease. 朱莉-马卡尼:利用创新应对镰状细胞病。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 DOI: 10.2471/BLT.24.031024

Julie Makani talks to Gary Humphreys about the need for guidance and policy to reflect developments in treatment of sickle cell disease.

朱莉-马卡尼(Julie Makani)与加里-汉弗莱斯(Gary Humphreys)讨论了制定指南和政策以反映镰状细胞病治疗发展的必要性。
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引用次数: 0
The case for mandatory - not voluntary - front-of-package nutrition labels. 包装正面营养标签应为强制性而非自愿性。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 Epub Date: 2024-09-11 DOI: 10.2471/BLT.24.292537
Lindsey Smith Taillie, Ana Clara Duran
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引用次数: 0
A continuous improvement agenda for WHO's normative and standard-setting functions. 世卫组织准则和标准制定职能的持续改进议程。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 DOI: 10.2471/BLT.24.292540
Lisa Askie, Kidist Bartolomeos, Jeremy Farrar, Mubashar Sheikh
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引用次数: 0
Voluntary versus mandatory food labels, Australia. 自愿与强制食品标签,澳大利亚。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 Epub Date: 2024-08-27 DOI: 10.2471/BLT.24.291629
Alexandra Jones, Damian Maganja, Maria Shahid, Bruce Neal, Simone Pettigrew

Objective: To compare uptake of the voluntary Health Star Rating front-of-pack nutrition labelling system with uptake of a mostly mandatory country-of-origin label in Australia over a similar period.

Methods: We used data on numbers and proportions of products carrying health stars and country-of-origin labelling recorded annually between 2015 and 2023 through surveys of four large Australian food retailers. We determined the proportion of products with health stars and country-of-origin labels for each year by dividing the number of products carrying each label by the total number eligible to carry that label.

Findings: The uptake of the voluntary Health Star Rating increased steadily between 2014 and 2018, reaching a maximum of 42% (8587/20 286) of products in 2021 before decreasing to 39% (8572/22 147) in 2023. Mandatory country-of-origin labelling uptake rose rapidly and was found on 93% (17 567/18 923) of products in 2023. In categories where country-of-origin labelling was voluntary, uptake by 2023 was 48% (3313/6925). In our 2023 sample of 22 147 products, 11 055 (50%) carried country-of-origin labelling only, 7466 (35%) carried both health star and country-of-origin labelling, 1106 (5%) carried health star labels only and 2520 (11%) carried neither label.

Conclusion: The experience with country-of-origin labelling shows that widespread and rapid food labelling change can be achieved when required by law. The Australian government should mandate the Health Star Rating without delay. Australia's experience supports other jurisdictions in implementing mandatory front-of-pack nutrition labelling as well as updates to global guidance to recognize mandatory labelling as best-practice in delivering benefits to consumers.

目的比较自愿性健康星级包装前营养标签系统与澳大利亚在类似时期内大多为强制性的原产国标签的使用情况:我们使用了 2015 年至 2023 年期间通过对澳大利亚四家大型食品零售商的调查每年记录的带有健康之星和原产国标签的产品数量和比例的数据。我们用贴有健康之星和原产国标签的产品数量除以有资格贴有该标签的产品总数,得出了每年贴有健康之星和原产国标签的产品比例:2014年至2018年期间,自愿性健康之星评级的采用率稳步上升,2021年达到42%(8587/20 286)的最高值,2023年降至39%(8572/22 147)。强制性原产国标签的采用率迅速上升,2023 年有 93% 的产品(17 567/18 923)采用了强制性原产国标签。至 2023 年,原产国标签自愿使用率为 48%(3313/6925)。在 2023 年抽样的 22 147 种产品中,11 055 种(50%)只贴有原产国标签,7466 种(35%)同时贴有健康之星和原产国标签,1106 种(5%)只贴有健康之星标签,2520 种(11%)两种标签都没有:结论:原产国标签的经验表明,在法律要求的情况下,食品标签可以实现广泛而迅速的改变。澳大利亚政府应立即强制推行健康星级评定。澳大利亚的经验支持其他司法管辖区实施强制性包装前营养标签以及更新全球指南,以确认强制性标签是为消费者带来益处的最佳做法。
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引用次数: 0
A WHO remit to improve global standards for medical products of human origin. 世卫组织的一项任务是改进全球人源医疗产品标准。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 Epub Date: 2024-09-02 DOI: 10.2471/BLT.24.291569
Eoin McGrath, Marisa R Herson, Matthew J Kuehnert, Karen Moniz, Zbigniew M Szczepiorkowski, Timothy L Pruett

In recent decades, considerable advances have been made in assuring the safety of blood transfusion and organ transplantation. However, with the increasing movement of medical products of human origin across international boundaries, there is a need to enhance global norms and governance. These products, which include blood, organs, tissues, cells, human milk and faecal microbiota, are today crucial for health care but they also pose unique risks due to their human origin, such as disease transmission and graft failure. Moreover, the demand for medical products of human origin often exceeds supply, leading to dependence on international supply chains, and emerging technologies like cell and gene therapy present further challenges because of their unproven efficacy and long-term risks. Current regulatory mechanisms, especially in low- and middle-income countries, are insufficient. The World Health Organization (WHO) has both the mandate and experience to lead the development of international quality and safety standards, consistent product nomenclature, and robust traceability and biovigilance systems. An international, multistakeholder approach is critical for addressing the complexities of how medical products of human origin are used globally and for ensuring their safety. This approach will require promoting uniform product descriptions, enhancing digital communication systems and leveraging existing resources to support countries in establishing regulations for these products. As illustrated by World Health Assembly resolution WHA77.4 on transplantation in 2024, WHO's ongoing efforts to ensure the safe, efficient and ethical use of medical products of human origin worldwide provide the opportunity to galvanize international cooperation on establishing norms.

近几十年来,在确保输血和器官移植安全方面取得了长足的进步。然而,随着源于人类的医疗产品越来越多地跨国流动,有必要加强全球规范和管理。这些产品包括血液、器官、组织、细胞、人乳和粪便微生物群,是当今医疗保健的关键,但也因其来源于人类而带来独特的风险,如疾病传播和移植失败。此外,人类来源的医疗产品往往供不应求,导致对国际供应链的依赖,而细胞和基因治疗等新兴技术因其未经证实的疗效和长期风险而带来更多挑战。目前的监管机制,尤其是中低收入国家的监管机制还不够完善。世界卫生组织(WHO)拥有领导制定国际质量和安全标准、统一产品命名以及健全的可追溯性和生物警戒系统的授权和经验。一个国际性的、多方利益相关者参与的方法对于解决全球范围内如何使用源自人类的医疗产品的复杂性以及确保其安全性至关重要。这种方法需要推广统一的产品说明,加强数字通信系统,并利用现有资源支持各国制定这些产品的法规。正如世界卫生大会关于 2024 年移植问题的第 WHA77.4 号决议所示,世卫组织正在努力确保在全球范围内安全、高效和合乎道德地使用源自人类的医疗产品,这为激发国际合作制定规范提供了机会。
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引用次数: 0
Community engagement in WHO guideline development. 社区参与世卫组织指南的制定。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 Epub Date: 2024-09-10 DOI: 10.2471/BLT.24.291579
Manjulaa Narasimhan, Patricia Mahecha Gutiérrez, Zoë Osborne, Muluba Habanyama, Karrie Worster, Carrie Martin, Angela Kaida
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引用次数: 0
Policy dimensions of global wastewater surveillance. 全球废水监控的政策层面。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.2471/BLT.24.292245
Megan B Diamond, Toni Whistler, Karina Rando, Chioma Nwachukwu, Mukhlid Yousif
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引用次数: 0
Public health round-up. 公共卫生综述。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.2471/BLT.24.010924
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引用次数: 0
District-level monitoring of universal health coverage, India. 印度县级全民医保监测。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 Epub Date: 2024-06-25 DOI: 10.2471/BLT.23.290854
Arnab Mukherji, Megha Rao, Sapna Desai, S V Subramanian, Gagandeep Kang, Vikram Patel

Objective: To develop a framework and index for measuring universal health coverage (UHC) at the district level in India and to assess progress towards UHC in the districts.

Methods: We adapted the framework of the World Health Organization and World Bank to develop a district-level UHC index (UHC d ). We used routinely collected health survey and programme data in India to calculate UHC d for 687 districts from geometric means of 24 tracer indicators in five tracer domains: reproductive, maternal, newborn and child health; infectious diseases; noncommunicable diseases; service capacity and access; and financial risk protection. UHC d is on a scale of 0% to 100%, with higher scores indicating better performance. We also assessed the degree of inequality within districts using a subset of 14 tracer indicators. The disadvantaged subgroups were based on four inequality dimensions: wealth quintile, urban-rural location, religion and social group.

Findings: The median UHC d was 43.9% (range: 26.4 to 69.4). Substantial geographical differences existed, with districts in southern states having higher UHC d than elsewhere in India. Service coverage indicator levels were greater than 60%, except for noncommunicable diseases and for service capacity and access. Health insurance coverage was limited, with about 10% of the population facing catastrophic and impoverishing health expenditure. Substantial wealth-based disparities in UHC were seen within districts.

Conclusion: Our study shows that UHC can be measured at the local level and can help national and subnational government develop prioritization frameworks by identifying health-care delivery and geographic hotspots where limited progress towards UHC is being made.

目标:制定衡量印度县级全民健康保险(UHC)的框架和指数,并评估各县在实现全民健康保险方面取得的进展:制定衡量印度县级全民健康覆盖率(UHC)的框架和指数,并评估各县在实现全民健康覆盖率方面取得的进展:我们对世界卫生组织和世界银行的框架进行了调整,以制定地区级全民健康覆盖指数(UHC d)。我们利用在印度例行收集的健康调查和计划数据,从生殖、孕产妇、新生儿和儿童健康、传染病、非传染性疾病、服务能力和获取途径以及金融风险保护这五个示踪领域的 24 个示踪指标的几何平均数中,计算出 687 个县的全民健康覆盖指数 d。全民健康覆盖率 d 采用 0% 到 100% 的评分标准,分数越高,表示表现越好。我们还使用 14 个跟踪指标子集评估了地区内的不平等程度。弱势分组基于四个不平等维度:财富五分位数、城乡位置、宗教和社会群体:全民保健覆盖率的中位数为 43.9%(范围:26.4 至 69.4)。存在很大的地域差异,南部各邦地区的全民健康覆盖率 d 值高于印度其他地区。除非传染性疾病以及服务能力和获取途径外,服务覆盖率指标水平均超过 60%。医疗保险覆盖面有限,约 10%的人口面临灾难性和贫困化的医疗支出。各地区在全民健康保险方面存在巨大的贫富差距:我们的研究表明,全民健康计划可以在地方层面进行衡量,并通过确定医疗服务提供情况以及全民健康计划进展有限的地理热点地区,帮助国家和国家以下各级政府制定优先事项框架。
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引用次数: 0
Wastewater surveillance to track influenza viruses. 跟踪流感病毒的废水监测。
IF 8.4 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.2471/BLT.24.292285
Leshan Xiu, Kun Yin
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引用次数: 0
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Bulletin of the World Health Organization
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