The importance of sodium ions both to the synthesis and to the release of acetylcholine in nerve terminals is demonstrated.
证明了钠离子对神经末梢乙酰胆碱的合成和释放的重要性。
{"title":"THE ROLE OF SODIUM IONS IN THE METABOLISM OF ACETYLCHOLINE.","authors":"R. Birks","doi":"10.1139/O63-289","DOIUrl":"https://doi.org/10.1139/O63-289","url":null,"abstract":"The importance of sodium ions both to the synthesis and to the release of acetylcholine in nerve terminals is demonstrated.","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"243 1","pages":"2573-97"},"PeriodicalIF":0.0,"publicationDate":"1963-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72938752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Male rats weighing 207 ± 2.38 g were exposed to cold (2–3 °C) for a period of 7 days during which urine and faeces were collected daily and analyzed for phosphorus. As a consequence of cold exposure, urinary excretion of phosphorus is increased. With free access to food, the increased food (and hence phosphorus) intake of the animals compensates for the increased urinary excretion and a normal phosphorus balance results. Cold exposure was without significant effect upon blood concentrations of acid-soluble, inorganic, organic, or lipid phosphorus. Increased inorganic and decreased organic, non-lipid phosphorus levels were observed in livers of cold-exposed rats. These observations suggest the breakdown of organic phosphates (e.g. hexose and triose phosphates, adenosine phosphates, phosphocreatine) to inorganic phosphorus.
{"title":"PHOSPHORUS METABOLISM IN COLD-EXPOSED RATS.","authors":"J. R. Beaton","doi":"10.1139/O63-249","DOIUrl":"https://doi.org/10.1139/O63-249","url":null,"abstract":"Male rats weighing 207 ± 2.38 g were exposed to cold (2–3 °C) for a period of 7 days during which urine and faeces were collected daily and analyzed for phosphorus. As a consequence of cold exposure, urinary excretion of phosphorus is increased. With free access to food, the increased food (and hence phosphorus) intake of the animals compensates for the increased urinary excretion and a normal phosphorus balance results. Cold exposure was without significant effect upon blood concentrations of acid-soluble, inorganic, organic, or lipid phosphorus. Increased inorganic and decreased organic, non-lipid phosphorus levels were observed in livers of cold-exposed rats. These observations suggest the breakdown of organic phosphates (e.g. hexose and triose phosphates, adenosine phosphates, phosphocreatine) to inorganic phosphorus.","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"92 1","pages":"2209-14"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75654250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Rapoport, D. Wilson, G. Ranking, L. W. White, W. Rudd
The left main renal artery was constricted in 41 dogs for intervals of 7 to 30 days. Separate urine collections from each kidney were then made during water diuresis and, in 28 of the dogs, during hypertonic urea diuresis. 'The rnost sensitive criteria of renal artery obstruction were combinations of urine volume and creatinine concentration ratios or of sodium and creatinine concentration ratios. To demonstrate enhanced water reabsorption by t he tubules of a kidney, there is no diagnostic advantage in the use of any one over another of the ratios of urine creatinine, urea, or para-amino hippurate. 'The filtration fraction of the constricted kidney was the same as that of the control. Thus the simpler measurement of each kidney's endogenous creatinine clearance offers the same assessment of relative kidney function as the technically more difficult measurement of separate para-amino hippurate clearances. When, under water diuresis, the urine concentration ratios of sodium and creatinine, as well as the urine volume ratio, are diagnostic, then urea infusions tend to blunt them. Conversely, when these ratios are not diagnostic, urea infusions tend to enhance them. Thus, for the greatest efficiency in the diagnosis of renal artery obstruction, separate urine collections should be made under conditions of both water and hypertonic urea diuresis.
{"title":"SEPARATE RENAL FUNCTION STUDIES IN DOGS WITH CHRONIC UNILATERAL RENAL ARTERY OBSTRUCTION. THE EFFECT OF HYPERTONIC UREA INFUSIONS.","authors":"A. Rapoport, D. Wilson, G. Ranking, L. W. White, W. Rudd","doi":"10.1139/O63-257","DOIUrl":"https://doi.org/10.1139/O63-257","url":null,"abstract":"The left main renal artery was constricted in 41 dogs for intervals of 7 to 30 days. Separate urine collections from each kidney were then made during water diuresis and, in 28 of the dogs, during hypertonic urea diuresis. 'The rnost sensitive criteria of renal artery obstruction were combinations of urine volume and creatinine concentration ratios or of sodium and creatinine concentration ratios. To demonstrate enhanced water reabsorption by t he tubules of a kidney, there is no diagnostic advantage in the use of any one over another of the ratios of urine creatinine, urea, or para-amino hippurate. 'The filtration fraction of the constricted kidney was the same as that of the control. Thus the simpler measurement of each kidney's endogenous creatinine clearance offers the same assessment of relative kidney function as the technically more difficult measurement of separate para-amino hippurate clearances. When, under water diuresis, the urine concentration ratios of sodium and creatinine, as well as the urine volume ratio, are diagnostic, then urea infusions tend to blunt them. Conversely, when these ratios are not diagnostic, urea infusions tend to enhance them. Thus, for the greatest efficiency in the diagnosis of renal artery obstruction, separate urine collections should be made under conditions of both water and hypertonic urea diuresis.","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"1 1","pages":"2273-85"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79534924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The respiratory quotient (R.Q.) of the rat diaphragm has been separately obtained for the three component regions of the diaphragm (dorsal 0.753, ventral 0.941, and lateral 1.143). It is pointed out that the generally accepted value of 0.7 for the rat diaphragm therefore cannot be regarded as a true index indicating the nature of the fuel metabolized in the diaphragm.
{"title":"RESPIRATORY QUOTIENT OF THE RAT DIAPHRAGM.","authors":"A. Susheela, J. C. George","doi":"10.1139/O63-251","DOIUrl":"https://doi.org/10.1139/O63-251","url":null,"abstract":"The respiratory quotient (R.Q.) of the rat diaphragm has been separately obtained for the three component regions of the diaphragm (dorsal 0.753, ventral 0.941, and lateral 1.143). It is pointed out that the generally accepted value of 0.7 for the rat diaphragm therefore cannot be regarded as a true index indicating the nature of the fuel metabolized in the diaphragm.","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"51 1","pages":"2221-3"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82855536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CHARACTERISTICS OF ERYTHROCYTES OF DIFFERENT AGES. II. ENZYME ACTIVITY AND OSMOTIC FRAGILITY.","authors":"M D SASS, L M LEVY, H WALTER","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"41 ","pages":"2287-96"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23672569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE CHEMICAL ANATOMY OF RAT SKIN.","authors":"P R SWEENY, R H PEARCE, H G VANCE","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"41 ","pages":"2307-26"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23672571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CONVERSION OF DISACCHARIDES TO THE CORRESPONDING GLYCOSIDE-3-ULOSES BY INTACT CELLS OF AGROBACTERIUM TUMEFACIENS.","authors":"S FUKUI, R M HOCHSTER","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"41 ","pages":"2363-71"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23672575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE CONCENTRATION OF FIBRINOLYSIN SOLUTIONS CONTAINING GLYCEROL.","authors":"R H PAINTER, G A MCVICAR","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"41 ","pages":"2269-72"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23672567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A RAPOPORT, D R WILSON, G N RANKING, L W WHITE, W W RUDD
{"title":"SEPARATE RENAL FUNCTION STUDIES IN DOGS WITH CHRONIC UNILATERAL RENAL ARTERY OBSTRUCTION. THE EFFECT OF HYPERTONIC UREA INFUSIONS.","authors":"A RAPOPORT, D R WILSON, G N RANKING, L W WHITE, W W RUDD","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"41 ","pages":"2273-85"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23672568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FORMATION OF UREA IN LIVER HOMOGENATES FROM CITRULLINE AND VARIOUS N-ALKYL DERIVATIVES OF ASPARTIC ACID.","authors":"R CHARBONNEAU, L BERLINGUET","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9531,"journal":{"name":"Canadian journal of biochemistry and physiology","volume":"41 ","pages":"2297-305"},"PeriodicalIF":0.0,"publicationDate":"1963-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23672570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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