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Canadian journal of ophthalmology. Journal canadien d'ophtalmologie最新文献

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Isolated case of noninfectious and nontraumatic panophthalmitis. 非感染性、非外伤性泛眼炎的孤立病例。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-05 DOI: 10.1016/j.jcjo.2024.07.011
Farnaz Javadian, Niveditha Pattathil, James Farmer, Robert J Campbell
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引用次数: 0
Advancing ocular oncology care through teleophthalmology: a patient-centric perspective. 通过远程眼科推进眼部肿瘤治疗:以患者为中心的视角。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.06.005
Paige Campbell, R Trafford Crump, Emily Laycock, Asher Khan, Ezekiel Weis

Objective: Assessing patient satisfaction is an important component of understanding a program's efficacy and quality. The purpose of this study is to evaluate patient satisfaction with a teleophthalmology program tailored for ocular oncology that provides screening, remote assessment, care planning, and follow-up.

Study design: Retrospective survey.

Methods: An adapted version of the Telehealth Satisfaction Scale, consisting of the 8 questions plus 5 additional questions specific to the teleophthalmology program, was used to survey patients. The teleophthalmology program involves diagnostic imaging, remote physician assessments, and follow-up phone calls from health care team members to deliver results to patients. For reporting, the Consensus-Based Checklist for Reporting of Survey Studies was used. T-tests explored satisfaction differences across demographics and teleophthalmology visits.

Results: Among the 95 patients contacted, 91 agreed to participate in the survey (96% response rate). Participants exhibited high overall satisfaction with the teleophthalmology program, reflected in a mean Telehealth Satisfaction Scale score of 28.88 (SD = 3.35 of 32). The median number of teleophthalmology visits completed was 4.0 (range of 1-8 appointments). No significant differences in satisfaction were found on the basis of age (P = 0.56), urban or rural residence (P = 0.17), or the number of telemedicine appointments (P = 0.51).

Conclusions: This analysis displays high satisfaction levels among patients within an ocular oncology clinic participating in the current telemedicine program, irrespective of age, geography, or number of teleophthalmology visits. Participants reported having their health care needs met with minimal clinical encounters due to remote consultations and telephone communications.

目的:评估患者满意度是了解项目疗效和质量的重要组成部分。本研究旨在评估患者对远程眼科项目的满意度,该项目为眼部肿瘤学量身定制,提供筛查、远程评估、护理计划和随访服务,并评估其在满足患者医疗保健需求方面的有效性:研究设计:回顾性调查:采用改编版远程医疗满意度量表对患者进行调查,该量表由 8 个问题和 5 个针对远程眼科项目的附加问题组成。远程眼科项目包括诊断成像、远程医生评估和医疗团队成员的后续电话,以便向患者提供结果。在报告方面,采用了基于共识的调查研究报告核对表:在所联系的 95 名患者中,有 91 人同意参与调查(回复率为 96%)。参与者对远程眼科项目的总体满意度很高,远程医疗满意度量表的平均值为 28.88(SD = 3.35,共 32 分)。远程眼科就诊次数的中位数为 4.0 次(1-8 次不等)。T 检验探讨了不同人口统计学特征和远程眼科就诊次数之间的满意度差异。在年龄(P = 0.56)、城乡居住地(P = 0.17)或远程医疗预约次数(P = 0.51)方面未发现明显差异:这项分析表明,无论年龄、地域或远程眼科就诊次数如何,参与当前远程医疗项目的眼部肿瘤诊所的患者对项目的满意度都很高。参加者表示,由于远程会诊和电话沟通,他们只需很少的临床接触就能满足自己的医疗保健需求。
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引用次数: 0
Prevalence and prediction of intraoperative floppy iris syndrome in patients with pseudoexfoliation syndrome. 假性虹膜脱落综合征患者术中虹膜松弛综合征的发生率和预测。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.06.006
Ron Eremenko, Eli Neimark, Daf Shalev, Gal Harel, Guy Kleinmann

Objective: To investigate the incidence of intraoperative floppy iris syndrome (IFIS) in patients with pseudoexfoliation syndrome (PXF) and analyze preoperative ocular predicting factors.

Design: A retrospective case-control study METHODS: The study included 224 eyes with PXF and 287 control eyes without PXF. One eye per patient, who underwent cataract surgery at the Wolfson Medical Center between January 2020 to December 2021, was included. Medical records of the patients were reviewed. Data collected included demographic characteristics, medical history, preoperative comprehensive ophthalmic examination, biometry, surgical procedure details, and IFIS occurrence. The association of IFIS with preoperative ocular parameters was analyzed through both univariant and multivariant analyses.

Results: Patients with PXF were older and had a higher prevalence of glaucoma (77.6 ± 6.4 years vs 74.2±7.6 years; p < 0.001, and 20.1 % vs 9.8 %, p < 0.001, respectively). Prevalence of α-blockers treatment was similar in both groups. IFIS rate among the PXF group was 12.5% (n = 28) compared to 7.3% (n = 21) in the control group (p < 0.05). When omitting patients exposed to α-blockers, the PXF group exhibited a significantly higher IFIS rate (9.9% vs 4.8%; p < 0.05). Pupil dilation diameter was significantly lower among PXF patients (5.8 ± 1.1 mm vs 6.9 ± 0.99 mm; p < 0.001). Biometric evaluation revealed significant differences in anterior segment depth (ACD) and lens thickness (LT). Multivariate analysis indicated that PXF and decreased mydriatic pupil size remained significant predictors of IFIS.

Conclusion: This study establishes an association between PXF and an increased risk of IFIS during cataract surgery, independent of α-blockers treatment.

目的调查假性虹膜外翻(PXF)患者术中虹膜松弛综合征(IFIS)的发生率,并分析术前眼部预测因素:设计:回顾性病例对照研究 方法:研究包括224只PXF患者眼和287只无PXF的对照眼。每位患者均有一只眼睛在 2020 年 1 月至 2021 年 12 月期间在沃尔夫森医疗中心接受了白内障手术。对患者的医疗记录进行了审查。收集的数据包括人口统计学特征、病史、术前眼科综合检查、生物测量、手术过程细节和 IFIS 发生情况。通过单变量和多变量分析,分析了 IFIS 与术前眼部参数的关系:结果:PXF 患者年龄更大,青光眼患病率更高(分别为 77.6 ± 6.4 岁 vs 74.2 ± 7.6 岁;P < 0.001;20.1% vs 9.8%,P < 0.001)。两组接受α-受体阻滞剂治疗的比例相似。PXF 组的 IFIS 率为 12.5%(28 人),而对照组为 7.3%(21 人)(P < 0.05)。如果剔除使用α-受体阻滞剂的患者,PXF 组的 IFIS 率明显更高(9.9% 对 4.8%;P < 0.05)。PXF 患者的瞳孔扩张直径明显较低(5.8 ± 1.1 mm vs 6.9 ± 0.99 mm;P < 0.001)。生物计量学评估显示,前节深度(ACD)和晶状体厚度(LT)存在明显差异。多变量分析表明,PXF 和瞳孔缩小仍是 IFIS 的重要预测因素:结论:本研究证实了 PXF 与白内障手术中 IFIS 风险增加之间存在关联,且与α-受体阻滞剂治疗无关。
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引用次数: 0
Reoperation for congenital ptosis: characteristics, success rates, and predicting factors. 先天性上睑下垂再手术:特点、成功率和预测因素。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.06.015
Ofri Vorobichik Berar, Eden Abergel, Guy Ben Simon, Mordechai Rosner, Ayelet Priel, Oded Sagiv, Daphna Landau Prat, Mattan Arazi, Ofira Zloto

Objective: Reoperation for congenital ptosis has added morbidity. The purpose of the current study was to examine the risk for redo ptosis surgery in patients with congenital ptosis, as well as to find predictive factors for reoperation.

Methods: This is a retrospective, cohort study. Analysis of all patients with congenital ptosis who underwent their first ptosis correction surgery between 2012 and 2021 at Sheba Medical Center was performed.

Results: Sixty patients (36 male and 24 female) underwent ptosis surgery for congenital ptosis Twenty nine patients (48.33%) underwent frontalis sling (FS), 13 patients (21.67%) underwent levator muscle (LM) surgeries, 9 patients received levator resection (LR), 4 patients received external levator advancement (LAA), and 18 patients (30%) underwent Müller's muscle-conjunctival resection (MMCR). Eighteen patients (30%) underwent a second ptosis surgery. The unadjusted risk of second ptosis surgery was almost four-fold among males with ptosis relative to females with ptosis (HR, 3.90; 95% CI, 3.67-547; p = 0.033) and higher among younger individuals (HR, 4.23; 95% CI, 3.33-5.62; p = 0.042). Older age was protective against the risk of second ptosis surgery (adjusted OR, 0.50; 95% CI, 0.21-0.60; p < 0.001), whereas male sex was associated with an increased likelihood of second ptosis surgery (adjusted OR, 3.33; 95% CI, 1.64-3.98; p < 0.001).

Conclusions: An increased risk of failure of the first surgery was found among male patients, younger patients, and patients with more severe ptosis before the first surgery. Awareness of those factors is beneficial for clinicians and parents.

背景:先天性上睑下垂再次手术会增加发病率。本研究旨在探讨先天性上睑下垂患者再次进行上睑下垂手术的风险,并找出再次手术的预测因素:这是一项回顾性队列研究。方法:这是一项回顾性队列研究,分析了2012年至2021年间在舍巴医疗中心接受首次上睑下垂矫正手术的所有先天性上睑下垂患者:60 名患者(36 名男性和 24 名女性)接受了先天性上睑下垂手术 29 名患者(48.33%)接受了额肌吊带术(FS),13 名患者(21.67%)接受了提上睑肌手术(LM),9 名患者接受了提上睑肌切除术(LR),4 名患者接受了提上睑肌外提术(LAA),18 名患者(30%)接受了缪勒肌-结膜切除术(MMCR)。18名患者(30%)接受了第二次上睑下垂手术。未经调整的二次上睑下垂手术风险在男性上睑下垂患者中几乎是女性上睑下垂患者的四倍(HR,3.90;95% CI,3.67-547;p = 0.033),在年轻人中则更高(HR,4.23;95% CI,3.33-5.62;p = 0.042)。年龄越大,第二次眼睑下垂手术的风险越低(调整后OR值为0.50;95% CI为0.21-0.60;p < 0.001),而男性与第二次眼睑下垂手术的可能性增加有关(调整后OR值为3.33;95% CI为1.64-3.98;p < 0.001):男性患者、年轻患者和第一次手术前上睑下垂较严重的患者第一次手术失败的风险增加。认识到这些因素对临床医生和家长都有好处。
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引用次数: 0
Inferior vitreous pathology imaged with ultra-wide-field OCT following pneumatic retinopexy. 气动视网膜整形术后的超宽视场 OCT 下玻璃体病理成像。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.07.010
Isabela Martins Melo, David T Wong, Rajeev H Muni
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引用次数: 0
Can high-resolution optical coherence tomography provide an optical biopsy for ocular surface lesions? 高分辨率光学相干断层扫描能否为眼表病变提供光学活检?
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.07.001
William R Herskowitz, Sofia De Arrigunaga, Jason A Greenfield, Noah K Cohen, Anat Galor, Carol L Karp

High-resolution optical coherence tomography (HR-OCT) has transformed the diagnosis and management of ocular surface lesions. Providing a detailed cross-sectional view of the cornea and conjunctiva, HR-OCT can be used to identify characteristic features of various benign and malignant ocular surface lesions, aiding in their diagnosis and guiding treatment. When incorporated into an ophthalmology clinic, HR-OCT provides morphological images of lesions in a noninvasive means, akin to an "optical biopsy". The characteristic HR-OCT features of several lesions have been well described in the literature, including for ocular surface squamous neoplasia, papilloma, melanoma, primary acquired melanosis, complexion associated melanosis, nevus, pterygium, pinguecula, lymphoma, and amyloidosis. HR-OCT can be used to differentiate between lesions with similar clinical features, lesions that co-exist on the same ocular surface, and atypically presenting lesions, such as pigmented ocular surface squamous neoplasia or amelanotic melanoma. The management of ocular surface lesions has been transformed by the implementation of HR-OCT, providing clinicians with the ability to monitor tumor response to topical chemotherapies, follow previously excised lesions for recurrence, and map out tumor borders intraoperatively. While there are some limitations to HR-OCT, including imaging of thick or deep lesions, it has become an essential tool for ocular oncologists in the management of ocular surface lesions.

高分辨率光学相干断层扫描(HR-OCT)改变了眼表病变的诊断和管理。HR-OCT 提供角膜和结膜的详细横截面图像,可用于识别各种良性和恶性眼表病变的特征,帮助诊断和指导治疗。在眼科临床中,HR-OCT 以类似 "光学活检 "的无创方式提供病变的形态学图像。一些病变的 HR-OCT 特征在文献中已有详细描述,包括眼表面鳞状细胞瘤、乳头状瘤、黑色素瘤、原发性获得性黑变病、肤色相关性黑变病、痣、翼状胬肉、胬肉、淋巴瘤和淀粉样变性。HR-OCT 可用于区分具有相似临床特征的病变、在同一眼表同时存在的病变以及表现不典型的病变,如色素性眼表鳞状上皮瘤或黑色素瘤。HR-OCT 的应用改变了眼表病变的治疗方法,使临床医生有能力监测肿瘤对局部化疗的反应,跟踪以前切除的病变是否复发,以及在术中绘制肿瘤边界。虽然 HR-OCT 还存在一些局限性,包括对较厚或较深病灶的成像,但它已成为眼部肿瘤专家治疗眼表病变的重要工具。
{"title":"Can high-resolution optical coherence tomography provide an optical biopsy for ocular surface lesions?","authors":"William R Herskowitz, Sofia De Arrigunaga, Jason A Greenfield, Noah K Cohen, Anat Galor, Carol L Karp","doi":"10.1016/j.jcjo.2024.07.001","DOIUrl":"10.1016/j.jcjo.2024.07.001","url":null,"abstract":"<p><p>High-resolution optical coherence tomography (HR-OCT) has transformed the diagnosis and management of ocular surface lesions. Providing a detailed cross-sectional view of the cornea and conjunctiva, HR-OCT can be used to identify characteristic features of various benign and malignant ocular surface lesions, aiding in their diagnosis and guiding treatment. When incorporated into an ophthalmology clinic, HR-OCT provides morphological images of lesions in a noninvasive means, akin to an \"optical biopsy\". The characteristic HR-OCT features of several lesions have been well described in the literature, including for ocular surface squamous neoplasia, papilloma, melanoma, primary acquired melanosis, complexion associated melanosis, nevus, pterygium, pinguecula, lymphoma, and amyloidosis. HR-OCT can be used to differentiate between lesions with similar clinical features, lesions that co-exist on the same ocular surface, and atypically presenting lesions, such as pigmented ocular surface squamous neoplasia or amelanotic melanoma. The management of ocular surface lesions has been transformed by the implementation of HR-OCT, providing clinicians with the ability to monitor tumor response to topical chemotherapies, follow previously excised lesions for recurrence, and map out tumor borders intraoperatively. While there are some limitations to HR-OCT, including imaging of thick or deep lesions, it has become an essential tool for ocular oncologists in the management of ocular surface lesions.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141892927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of binocular reading speed in patients with strabismus without amblyopia versus controls. 无弱视的斜视患者与对照组的双眼阅读速度比较。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.06.017
Daniel Lamoureux, Sarah Yeo, Vishaal Bhambhwani

Objective: Amblyopia has been shown to slow reading speed. Limited literature exists on reading speed in strabismus without amblyopia. Our study compares binocular reading speed in patients with strabismus without amblyopia versus normal controls.

Methods: We conducted a prospective study with 48 participants: 12 childhood-onset (onset <8 years of age) strabismus without amblyopia and 36 age- and education level-matched controls. Inclusion criteria were age 14-50 years, education >9 years, primary language English, best-corrected visual acuity >20/30 distance, and >N8 near either eye. Exclusion criteria were presence of other eye pathology or neurologic/cognitive conditions that may affect reading and previous treatment for strabismus/amblyopia. International Reading Speed Texts were used for binocular reading speed assessment. Each participant read 2 passages (passage 1 and 8), following all International Reading Speed Texts instructions. Reading time was measured using a stopwatch. Reading speed was calculated in words per minute (WPM).

Results: Mean age for the strabismus group was 28.3 ± 11.1 and for the control group was 28.2 ± 11.0 years (P = 0.96). Mean education level for strabismus group was 14.2 ± 2.4 and control group was 13.8 ± 2.5 years (P = 0.62). Mean binocular reading speed for passage 1 for strabismus group was 192.0 and for control group was 220.0 WPM (P = 0.01). Mean binocular reading speed for passage 8 for strabismus group was 201.3 and for control group was 226.2 WPM (P = 0.04).

Conclusions: Patients with strabismus (without amblyopia) had slower binocular reading speed compared with controls. Further studies with eye tracking may provide more information. Strabismus, even without amblyopia, may affect reading performance and consequently vision-related quality of life.

目的:弱视已被证明会降低阅读速度。有关无弱视斜视患者阅读速度的文献有限。我们的研究比较了无弱视斜视患者与正常对照组患者的双眼阅读速度:我们对 48 名参与者进行了前瞻性研究:12名儿童期患者(发病年龄为9岁,主要语言为英语,最佳矫正视力>20/30,近距离视力>N8。排除标准为存在可能影响阅读的其他眼部病变或神经/认知疾病,以及曾接受过斜视/弱视治疗。双目阅读速度评估采用国际阅读速度文本。每位受试者阅读 2 个段落(段落 1 和段落 8),并按照国际阅读速度文本的所有说明进行阅读。阅读时间用秒表测量。阅读速度以每分钟字数(WPM)计算:斜视组的平均年龄为(28.3 ± 11.1)岁,对照组的平均年龄为(28.2 ± 11.0)岁(P = 0.96)。斜视组的平均受教育程度为(14.2 ± 2.4)年,对照组为(13.8 ± 2.5)年(P = 0.62)。斜视组第一段的平均双眼阅读速度为 192.0 WPM,对照组为 220.0 WPM(P = 0.01)。斜视组阅读第 8 段的平均双眼阅读速度为 201.3,对照组为 226.2 WPM(P = 0.04):斜视患者(无弱视)的双眼阅读速度低于对照组患者。使用眼动仪进行的进一步研究可能会提供更多信息。斜视,即使没有弱视,也可能影响阅读能力,进而影响与视力相关的生活质量。
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引用次数: 0
Treatment of conjunctival palpebral lesions using ruthenium plaque brachytherapy "Sandwich Technique". 使用钌斑块近距离放射疗法 "三明治技术 "治疗结膜睑缘病变。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.07.003
Shahar Frenkel, Jacob Pe'er, Yael Deckel, Zvi Gur, Shay Ofir, Maya Eiger-Moscovich

Objective: Treatment of palpebral conjunctival lesions is problematic due to late diagnosis, difficult surgical approach, and the need to preserve eyelid integrity. We describe our treatment experience using plaque brachytherapy in the "sandwich technique."

Design: A retrospective study.

Participants: We reviewed the medical records of patients treated by plaque brachytherapy for conjunctival lesions at the Hadassah Medical Center between January 1, 2013, and January 1, 2024, and included in the analysis patients treated for palpebral conjunctival lesions.

Methods: Ruthenium plaque was sutured to the palpebral conjunctiva. The matching nonradioactive "dummy" plaque was sutured to the external eyelid to flip the tarsal's curvature.

Results: The study cohort included 5 patients, 2 men (40%) and 3 women (60%) at a median age of 68.11 years (range: 47-79.7 years). Three patients had conjunctival melanoma (60%), 1 had sebaceous carcinoma (20%), and 1 had extensive carcinoma in situ (20%). All lesions were in the left upper eyelid. Median follow-up was 37.6 months (range: 18.7-110.6 months). Four patients demonstrated a complete response (80%), while one had a partial response (20%). There was local recurrence in 1 patient (20%), and 1 patient had new foci elsewhere (20%). All patients had full local control after adding local treatments. One patient developed metastatic disease and died (20%). All patients had manageable madarosis and conjunctival scars.

Conclusions: Treatment of palpebral conjunctival lesions using "sandwich" plaque brachytherapy is safe and effective. To the best of our knowledge, this treatment was never described before, and we believe it should be added to our armamentarium.

目的:睑结膜病变的治疗由于诊断较晚、手术方法困难以及需要保持眼睑的完整性而成为难题。设计:一项回顾性研究:回顾性研究:我们回顾了哈大沙医疗中心在 2013 年 1 月 1 日至 2024 年 1 月 1 日期间采用斑块近距离放射治疗结膜病变患者的病历,并将睑结膜病变患者纳入分析范围:将钌斑块缝合到睑结膜上。方法:将钌斑块缝合在睑结膜上,并将匹配的非放射性 "假 "斑块缝合在外侧眼睑上,以翻转跗骨弧度:研究对象包括 5 名患者,其中男性 2 名(占 40%),女性 3 名(占 60%),中位年龄为 68.11 岁(范围:47-79.7 岁)。3名患者患有结膜黑色素瘤(60%),1名患者患有皮脂腺癌(20%),1名患者患有广泛原位癌(20%)。所有病变均位于左上眼睑。中位随访时间为 37.6 个月(18.7-110.6 个月)。四名患者完全康复(80%),一名患者部分康复(20%)。1名患者出现局部复发(20%),1名患者在其他部位出现新病灶(20%)。所有患者在接受局部治疗后都完全控制了病情。一名患者出现转移性疾病并死亡(20%)。所有患者的睑结膜病变和结膜疤痕均可控制:结论:使用 "三明治 "斑块近距离放射治疗睑结膜病变是安全有效的。据我们所知,这种治疗方法以前从未被描述过,我们认为应该将其添加到我们的武器库中。
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引用次数: 0
Clinicopathologic features and new factors affecting constitution of eyelid neoplasms: a 10-year multicentre experience in southern coastal China. 影响眼睑肿瘤构成的临床病理特征和新因素:中国南部沿海地区多中心 10 年的经验。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.06.014
Yu Wu, Hongliang Zhong, Zhenyang Xiang, Pin Zhou, Hui Wang, Xin Song, Yimin Li

Objective: This study aims to delineate the key characteristics of eyelid neoplasms in central and southern coastal China and to explore potential factors affecting tumour development.

Methods: This was a retrospective, multicentre observational study. In total, 1302 cases of eyelid neoplasms diagnosed in 2 tertiary hospitals were reviewed from January 2013 to May 2023. Histogenesis, pathologic diagnosis, and potential risk factors were investigated, and the findings were compared with data from various regions and countries. Age- and sex-specific incidence rates, time trends, distributions across age groups, and the relationship with the Sociodemographic Index, latitude, and altitude were calculated.

Results: There were 1162 benign (89.2%) and 140 malignant (10.8%) cases, representing 63 pathologic types. The median age of benign cases (50 years) was significantly lower than that of malignant cases (72 years) (P < 0.05). The most common benign and malignant lesions were intradermal nevus (28.83%) and basal cell carcinoma (BCC) (74.29%). A relatively younger median age (68 years) for sebaceous gland carcinoma (SGC) was observed, with a male preponderance (sex ratio 2:1). Analyses of the proportions of BCC, SGC, and squamous cell carcinoma in eyelid malignancies revealed significant regression equations (P < 0.05).

Conclusions: Most eyelid neoplasms are of epithelial and melanocytic origin, with benign tumours being predominant. The regions with greater Sociodemographic Index exhibit a greater incidence of BCC and a lower incidence of squamous cell carcinoma and SGC. BCC appears to have a greater incidence in regions located at higher latitudes.

背景:本研究旨在描述中国中部和南部沿海地区眼睑肿瘤的主要特征,并探讨影响肿瘤发展的潜在因素:本研究旨在描述中国中部和南部沿海地区眼睑肿瘤的主要特征,并探讨影响肿瘤发生的潜在因素:方法:这是一项多中心回顾性观察研究。方法:这是一项回顾性多中心观察研究。研究回顾了 2013 年 1 月至 2023 年 5 月期间在两家三甲医院确诊的 1302 例眼睑肿瘤病例。研究对组织发生、病理诊断和潜在风险因素进行了调查,并将调查结果与不同地区和国家的数据进行了比较。计算了特定年龄和性别的发病率、时间趋势、各年龄组的分布以及与社会人口指数、纬度和海拔的关系:共有 1162 例良性病例(占 89.2%)和 140 例恶性病例(占 10.8%),代表 63 种病理类型。良性病例的中位年龄(50 岁)明显低于恶性病例(72 岁)(P < 0.05)。最常见的良性和恶性病变是皮内痣(28.83%)和基底细胞癌(74.29%)。皮脂腺癌(SGC)的中位年龄相对较小(68 岁),男性居多(性别比为 2:1)。对眼睑恶性肿瘤中 BCC、SGC 和鳞状细胞癌的比例进行分析,发现了显著的回归方程(P < 0.05):结论:大多数眼睑肿瘤为上皮性和黑色素细胞性肿瘤,以良性肿瘤为主。社会人口指数较高的地区 BCC 发病率较高,鳞状细胞癌和 SGC 发病率较低。纬度较高地区的 BCC 发病率似乎更高。
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引用次数: 0
Switching from intravenous to subcutaneous tocilizumab for uveitis during the COVID-19 pandemic: a case series. 在 COVID-19 大流行期间从静脉注射转为皮下注射托珠单抗治疗葡萄膜炎:病例系列。
IF 3.3 4区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-03 DOI: 10.1016/j.jcjo.2024.06.016
Nitesh Mohan, Sunil K Srivastava, Kimberly Baynes, Careen Y Lowder, Sumit Sharma
{"title":"Switching from intravenous to subcutaneous tocilizumab for uveitis during the COVID-19 pandemic: a case series.","authors":"Nitesh Mohan, Sunil K Srivastava, Kimberly Baynes, Careen Y Lowder, Sumit Sharma","doi":"10.1016/j.jcjo.2024.06.016","DOIUrl":"10.1016/j.jcjo.2024.06.016","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
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