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La compassion ne doit pas être une ressource limitée dans les soins de santé des personnes transgenres et de la diversité des genres. 在变性人和不同性别者的医疗保健中,同情心绝不能成为有限的资源。
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-30 DOI: 10.1503/cmaj.240878-f
Kirsten Patrick
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引用次数: 0
Mycoplasma pneumoniae. 肺炎支原体
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-30 DOI: 10.1503/cmaj.240085
Maude Paquette, Matthew Magyar, Christian Renaud
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引用次数: 0
Invasive ductal carcinoma of the nipple in a man. 一名男性的乳头浸润性导管癌。
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-30 DOI: 10.1503/cmaj.240625
Chia-Lun Li, Chen-Yi Wu
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引用次数: 0
Private insurance should have a role in the Pharmacare Act. 私人保险应该在《药管法》中发挥作用。
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-30 DOI: 10.1503/cmaj.151284-l
Chris G Bonnett
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引用次数: 0
Vaginose bactérienne. 细菌性阴道炎
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-22 DOI: 10.1503/cmaj.231688-f
Michal Braunstein, Amanda Selk
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引用次数: 0
Notes de la vie sous l’eau. 水下生活笔记
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-22 DOI: 10.1503/cmaj.240084-f
Neal Auch
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引用次数: 0
My hasty heart. 我匆忙的心
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-22 DOI: 10.1503/cmaj.240172
Kate Braid
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引用次数: 0
A 58-year-old man with subacute digital ischemia of all limbs. 一名 58 岁的男子患有四肢亚急性数字缺血。
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-22 DOI: 10.1503/cmaj.240399
Marc-Alexandre Lavoie, Alain Milot
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引用次数: 0
Alcalose métabolique et hypokaliémie chez une femme de 23 ans. 一名 23 岁女性的代谢性碱中毒和低钾血症。
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-22 DOI: 10.1503/cmaj.240163-f
Kamel S Kamel, Joshua Shapiro, Ziv Harel
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引用次数: 0
"Before medically advised" departure from hospital and subsequent drug overdose: a population-based cohort study. "医疗建议前 "离开医院与随后的吸毒过量:一项基于人群的队列研究。
IF 9.4 1区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-22 DOI: 10.1503/cmaj.240364
Mayesha Khan, Xiao Nicole, Alexis Crabtree, Jessica Moe, Trudy Nasmith, Daniel Daly-Grafstein, Jeffrey R Brubacher, Amanda K Slaunwhite, John A Staples

Background: A substantial number of hospital admissions end in patient-initiated departure before medical treatment is complete. Whether "before medically advised" (BMA) discharge increases the risk of subsequent drug overdose remains uncertain.

Methods: We performed a retrospective cohort study using administrative health data from a 20% random sample of residents of British Columbia, Canada. We focused on nonelective, nonobstetric hospital stays occurring between 2015 and 2019. We used survival analysis to compare the rate of fatal or nonfatal illicit drug overdose in the first 30 days after BMA discharge versus the rate after physician-advised discharge.

Results: Overall, 6440 of 189 808 (3.4%) hospital stays ended in BMA discharge. Among 820 overdoses occurring in the first 30 days after any hospital discharge, 755 (92%) involved patients with a history of substance use disorder. Unadjusted overdose rates were 10-fold higher after BMA discharge than after physician-advised discharge, and BMA discharge was associated with subsequent overdose even after adjustment for potential confounders (crude incidence, 2.8% v. 0.3%; adjusted hazard ratio [HR] 1.58; 95% confidence interval [CI] 1.31-1.89). Before medically advised discharge was associated with increases in subsequent emergency department visits (adjusted HR 1.92; 95% CI 1.83-2.02) and unplanned hospital readmissions (adjusted HR 2.07; 95% CI 1.96-2.19), but there was no significant association with the uncommon outcomes of fatal overdose and all-cause mortality.

Interpretation: Before medically advised departure is associated with an increased risk of drug overdose in the first 30 days after discharge. Improved treatment of substance use disorder, expanded access to overdose prevention services, and new means of postdeparture outreach should be explored to reduce this risk.

背景:大量入院患者在治疗结束前主动离院。至于 "医嘱前"(BMA)出院是否会增加后续药物过量的风险,目前仍不确定:我们利用加拿大不列颠哥伦比亚省 20% 随机抽样居民的健康管理数据进行了一项回顾性队列研究。我们重点研究了 2015 年至 2019 年期间发生的非选择性、非产科住院。我们使用生存分析法比较了 BMA 出院后前 30 天内致命或非致命非法药物过量率与医生建议出院后的比率:总体而言,189 808 次住院治疗中有 6440 次(3.4%)以 BMA 出院告终。在出院后 30 天内发生的 820 例用药过量中,有 755 例(92%)患者有药物使用障碍病史。在BMA出院后,未经调整的用药过量率是医生建议出院后的10倍,即使在调整了潜在的混杂因素后,BMA出院仍与随后的用药过量有关(粗略发生率为2.8%对0.3%;调整后的危险比[HR]为1.58;95%置信区间[CI]为1.31-1.89)。医疗建议出院前与后续急诊就诊率(调整后的危险比为 1.92;95% 置信区间为 1.83-2.02)和非计划再入院率(调整后的危险比为 2.07;95% 置信区间为 1.96-2.19)的增加有关,但与致命性药物过量和全因死亡率等非常见结果无显著关联:医学建议的出院前与出院后前 30 天药物过量风险的增加有关。为降低这一风险,应探索改进药物使用障碍的治疗、扩大预防用药过量服务的可及性以及出院后外联的新方法。
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引用次数: 0
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Canadian Medical Association journal
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