Pub Date : 2026-02-07DOI: 10.1186/s40959-026-00451-9
Daniel Finke, Markus B Heckmann, Jessica M Schug, Lukas F Entenmann, Hauke Hund, Hugo A Katus, Norbert Frey, Lorenz H Lehmann
{"title":"The impact of acute coronary syndrome on long-term survival in cancer patients.","authors":"Daniel Finke, Markus B Heckmann, Jessica M Schug, Lukas F Entenmann, Hauke Hund, Hugo A Katus, Norbert Frey, Lorenz H Lehmann","doi":"10.1186/s40959-026-00451-9","DOIUrl":"https://doi.org/10.1186/s40959-026-00451-9","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-04DOI: 10.1186/s40959-026-00448-4
Shaghayegh Kamian, Payam Azadeh, Robab Anbiaee, Ahmad Mafi, Hasan Ashoori, Hamed Ghoshouni, Mohammad Javad Bahadori, Tannaz Malakouti
{"title":"Changes in circulating miR-199a, cardiac troponin I, NT-proBNP, and left ventricular ejection fraction during anthracycline therapy in breast cancer patients.","authors":"Shaghayegh Kamian, Payam Azadeh, Robab Anbiaee, Ahmad Mafi, Hasan Ashoori, Hamed Ghoshouni, Mohammad Javad Bahadori, Tannaz Malakouti","doi":"10.1186/s40959-026-00448-4","DOIUrl":"https://doi.org/10.1186/s40959-026-00448-4","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-27DOI: 10.1186/s40959-025-00430-6
Raúl Ramos-Polo, Santiago Jiménez-Marrero, Herminio Morillas, Alexandra Pons-Riverola, Alberto Garay, Itziar Carro, Laura Maria Gràcia, Núria Baixeras, Jesús Sánchez-Vega, Pedro Moliner
{"title":"Two types amyloid infiltration of the heart: diagnostic challenges and therapeutic strategies.","authors":"Raúl Ramos-Polo, Santiago Jiménez-Marrero, Herminio Morillas, Alexandra Pons-Riverola, Alberto Garay, Itziar Carro, Laura Maria Gràcia, Núria Baixeras, Jesús Sánchez-Vega, Pedro Moliner","doi":"10.1186/s40959-025-00430-6","DOIUrl":"https://doi.org/10.1186/s40959-025-00430-6","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146060624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1186/s40959-025-00417-3
Henrietta Afari, Congying Xia, Julius Mwita, Thato Moshomo, Anran Huang, Maliha Shaikh, Sebaga W Motlhwa, Tlotlo Ralefala, Peter Vuylsteke, Scott Dryden-Peterson, Priscilla Y Hsue, Robert Gross, Mosepele Mosepele, Bonnie Ky, Yehoda M Martei
Background: HIV, cancer, and their respective treatments are independently associated with cardiovascular risk, but limited data exist on the intersection of these conditions. The purpose of this study was to gain insights into the cardiovascular risk factor burden and cardiac function in people with HIV (PWH) treated for breast cancer.
Methods: In a cohort of PWH and breast cancer treated with anthracyclines and/or trastuzumab (2017-2022) in Botswana, we assessed pre-treatment (baseline) left ventricular ejection fraction (LVEF), and prospectively obtained an echocardiogram at least one year after cancer treatment initiation. Wilcoxon signed rank sum test was used to test the differences between baseline and follow-up LVEF.
Results: Thirty-three women were enrolled at a median of 2.1 years (Quartile (Q)1-Q3 1.8-3.1) from their cancer treatment initiation. The median age was 48.0 years (Q1-Q3 44.0-54.0). All but one patient was on antiretroviral therapy (ART); the median ART duration was 11.6 years (Q1-Q3 6.3-15 years) with a median viral load of 30 (Q1-Q3 0-30) and CD4 count of 874 (Q1-Q3 361-1131). At baseline, 70% were obese or overweight, and 24.2% reported hypertension; this increased to 30.3% at follow-up. The median LVEF at baseline was 65% (Q1-Q3 60-68%), and decreased to 62% (Q1-Q3 59-65%) at follow-up; an absolute difference of 2.9%, 95%CI: -5.3 to -0.2% (p = 0.038). There was no report of clinical heart failure.
Conclusions: Obesity and hypertension are highly prevalent amongst PWH and breast cancer. We also noted a statistically significant, but modest decline in LVEF after cancer therapy initiation. Further studies are needed to prospectively characterize the cardiovascular risk factor burden and changes in cardiac structure and function following cardiotoxic cancer treatment in this population.
{"title":"Cardiovascular risk factors and cardiac dysfunction in people with HIV and breast cancer: an observational cohort study in Botswana.","authors":"Henrietta Afari, Congying Xia, Julius Mwita, Thato Moshomo, Anran Huang, Maliha Shaikh, Sebaga W Motlhwa, Tlotlo Ralefala, Peter Vuylsteke, Scott Dryden-Peterson, Priscilla Y Hsue, Robert Gross, Mosepele Mosepele, Bonnie Ky, Yehoda M Martei","doi":"10.1186/s40959-025-00417-3","DOIUrl":"10.1186/s40959-025-00417-3","url":null,"abstract":"<p><strong>Background: </strong>HIV, cancer, and their respective treatments are independently associated with cardiovascular risk, but limited data exist on the intersection of these conditions. The purpose of this study was to gain insights into the cardiovascular risk factor burden and cardiac function in people with HIV (PWH) treated for breast cancer.</p><p><strong>Methods: </strong>In a cohort of PWH and breast cancer treated with anthracyclines and/or trastuzumab (2017-2022) in Botswana, we assessed pre-treatment (baseline) left ventricular ejection fraction (LVEF), and prospectively obtained an echocardiogram at least one year after cancer treatment initiation. Wilcoxon signed rank sum test was used to test the differences between baseline and follow-up LVEF.</p><p><strong>Results: </strong>Thirty-three women were enrolled at a median of 2.1 years (Quartile (Q)1-Q3 1.8-3.1) from their cancer treatment initiation. The median age was 48.0 years (Q1-Q3 44.0-54.0). All but one patient was on antiretroviral therapy (ART); the median ART duration was 11.6 years (Q1-Q3 6.3-15 years) with a median viral load of 30 (Q1-Q3 0-30) and CD4 count of 874 (Q1-Q3 361-1131). At baseline, 70% were obese or overweight, and 24.2% reported hypertension; this increased to 30.3% at follow-up. The median LVEF at baseline was 65% (Q1-Q3 60-68%), and decreased to 62% (Q1-Q3 59-65%) at follow-up; an absolute difference of 2.9%, 95%CI: -5.3 to -0.2% (p = 0.038). There was no report of clinical heart failure.</p><p><strong>Conclusions: </strong>Obesity and hypertension are highly prevalent amongst PWH and breast cancer. We also noted a statistically significant, but modest decline in LVEF after cancer therapy initiation. Further studies are needed to prospectively characterize the cardiovascular risk factor burden and changes in cardiac structure and function following cardiotoxic cancer treatment in this population.</p>","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":"12 1","pages":"9"},"PeriodicalIF":3.2,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1186/s40959-026-00443-9
Swati D Sonkawade, Lee D Chavez, Shirley Xu, Xiaoyi Ma, Sarmila Nepali, Steven E Lipshultz, Saraswati Pokharel, Umesh C Sharma
{"title":"Macrophage surface protein Mac-2 mediates inflammatory and stromal stress pathways in doxorubicin-induced cardiac injury.","authors":"Swati D Sonkawade, Lee D Chavez, Shirley Xu, Xiaoyi Ma, Sarmila Nepali, Steven E Lipshultz, Saraswati Pokharel, Umesh C Sharma","doi":"10.1186/s40959-026-00443-9","DOIUrl":"https://doi.org/10.1186/s40959-026-00443-9","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-19DOI: 10.1186/s40959-025-00428-0
Cheng Hwee Soh, Shristy Shrestha, Kristyn Whitmore, Batsheva Greenbaum, Atro Azad, Melinda J Carrington, Joel Smith, Thomas H Marwick
{"title":"Statin initiation among cancer survivors with asymptomatic coronary atherosclerosis.","authors":"Cheng Hwee Soh, Shristy Shrestha, Kristyn Whitmore, Batsheva Greenbaum, Atro Azad, Melinda J Carrington, Joel Smith, Thomas H Marwick","doi":"10.1186/s40959-025-00428-0","DOIUrl":"https://doi.org/10.1186/s40959-025-00428-0","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-15DOI: 10.1186/s40959-025-00424-4
Abdelrahman El-Helbawy, Sara T Zaki, Fouad Hanna, Mohamed Bassiouni, Khaled O Yaseen, Amany H Ali, Oliver M Farid
{"title":"Cardioprotective effect of diabetic medication on cancer patients undergoing proven cardiotoxic chemotherapy: a systematic review and meta-analysis.","authors":"Abdelrahman El-Helbawy, Sara T Zaki, Fouad Hanna, Mohamed Bassiouni, Khaled O Yaseen, Amany H Ali, Oliver M Farid","doi":"10.1186/s40959-025-00424-4","DOIUrl":"10.1186/s40959-025-00424-4","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":"14"},"PeriodicalIF":3.2,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12853835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145988424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1186/s40959-025-00442-2
Alexander Jp Fulton, Mun Cheang, Maria Ta Wetscherek, Paul Cacciottolo, Jean E Abraham
{"title":"Abemaciclib-induced myocarditis in early breast cancer: a case report.","authors":"Alexander Jp Fulton, Mun Cheang, Maria Ta Wetscherek, Paul Cacciottolo, Jean E Abraham","doi":"10.1186/s40959-025-00442-2","DOIUrl":"https://doi.org/10.1186/s40959-025-00442-2","url":null,"abstract":"","PeriodicalId":9804,"journal":{"name":"Cardio-oncology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145970660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号