Pub Date : 2022-03-01DOI: 10.3390/chemproc2022007015
G. Petrișor, Ludmila Motelica, R. Trusca, V. Ene, D. Ficai, O. Oprea, G. Voicu, A. Ficai
In this work, we obtain mesoporous silica systems loaded with polyphenolic compounds (p-coumaric acid, trans-ferulic acid, epicatechin, and catechin). Polyphenolic compounds are used as biologically active agents for the treatment of various diseases. These compounds have high antioxidant activity. As a carrier, two types of mesoporous silica have been proposed and obtained according to the classical templating method with cetyltrimethylammonium bromide, CTAB, under alkaline conditions. Polyphenols (p-coumaric acid, trans-ferulic acid, epicatechin, and catechin) were loaded under vacuum into the mesoporous silica. The materials obtained were characterized by Scanning Electron Microscopy, X-ray Diffraction, the Brunauer–Emmett–Teller Method, Complex Thermal Analysis–DTA-TG and Fourier Transform Infrared Spectroscopy. In this study, mesoporous silica systems were obtained and further loaded with p-coumaric acid, trans-ferulic acid, epicatechin and catechin. The results highlight that the materials can be used as drug delivery systems, with the results being promising (simulated gastric fluid, SGF, and simulated intestinal fluid, SIF) for various environments. The proposed loading methodology is suitable for loading these natural agents, mostly, inside the pores.
{"title":"Mesoporous Silica Systems Loaded with Polyphenols","authors":"G. Petrișor, Ludmila Motelica, R. Trusca, V. Ene, D. Ficai, O. Oprea, G. Voicu, A. Ficai","doi":"10.3390/chemproc2022007015","DOIUrl":"https://doi.org/10.3390/chemproc2022007015","url":null,"abstract":"In this work, we obtain mesoporous silica systems loaded with polyphenolic compounds (p-coumaric acid, trans-ferulic acid, epicatechin, and catechin). Polyphenolic compounds are used as biologically active agents for the treatment of various diseases. These compounds have high antioxidant activity. As a carrier, two types of mesoporous silica have been proposed and obtained according to the classical templating method with cetyltrimethylammonium bromide, CTAB, under alkaline conditions. Polyphenols (p-coumaric acid, trans-ferulic acid, epicatechin, and catechin) were loaded under vacuum into the mesoporous silica. The materials obtained were characterized by Scanning Electron Microscopy, X-ray Diffraction, the Brunauer–Emmett–Teller Method, Complex Thermal Analysis–DTA-TG and Fourier Transform Infrared Spectroscopy. In this study, mesoporous silica systems were obtained and further loaded with p-coumaric acid, trans-ferulic acid, epicatechin and catechin. The results highlight that the materials can be used as drug delivery systems, with the results being promising (simulated gastric fluid, SGF, and simulated intestinal fluid, SIF) for various environments. The proposed loading methodology is suitable for loading these natural agents, mostly, inside the pores.","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77338469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007013
A. Vlaicu, Mihaela Cîlțea-Udrescu, A. Vintilă, Grigore Pșenovschi, Anca Paulenco, A. Galán
Nowadays, the interest for high-quality products of natural origin is increasing worldwide [...]
如今,世界范围内对高质量天然产品的兴趣日益浓厚[…]
{"title":"Stability of Bioactive Extracts from Porphyridium purpureum Microalgae Biomass under Various Stress Factors","authors":"A. Vlaicu, Mihaela Cîlțea-Udrescu, A. Vintilă, Grigore Pșenovschi, Anca Paulenco, A. Galán","doi":"10.3390/chemproc2022007013","DOIUrl":"https://doi.org/10.3390/chemproc2022007013","url":null,"abstract":"Nowadays, the interest for high-quality products of natural origin is increasing worldwide [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79073385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007009
A. Sorescu, A. Nuta, R. Ion, V. Rădițoiu, L. Marin
Introduction: Silver nanoparticles (AgNPs), widely recognized for their antimicrobial and antioxidant capacity, can be prepared following both conventional and unconventional routes and have a multitude of applications in numerous scientific domains, including the catalytic degradation of dyes that result from the textile industry [...]
{"title":"Evaluation of the Catalytic Degradation Capacity of Green Synthesized Silver Nanoparticles on Bis-Azoic Dyes","authors":"A. Sorescu, A. Nuta, R. Ion, V. Rădițoiu, L. Marin","doi":"10.3390/chemproc2022007009","DOIUrl":"https://doi.org/10.3390/chemproc2022007009","url":null,"abstract":"Introduction: Silver nanoparticles (AgNPs), widely recognized for their antimicrobial and antioxidant capacity, can be prepared following both conventional and unconventional routes and have a multitude of applications in numerous scientific domains, including the catalytic degradation of dyes that result from the textile industry [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81530603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007011
A. Vintilă, A. Vlaicu, Mihaela Cîlțea-Udrescu, Luiza Mîrț, A. Galán, Anca Paulenco
The dairy industry is one of the main sources of agro-industrial wastewater [...]
乳业是农业工业废水的主要来源之一[…]
{"title":"Treatment of Dairy Wastewaters Using Nannochloris sp. Microalgae Strain","authors":"A. Vintilă, A. Vlaicu, Mihaela Cîlțea-Udrescu, Luiza Mîrț, A. Galán, Anca Paulenco","doi":"10.3390/chemproc2022007011","DOIUrl":"https://doi.org/10.3390/chemproc2022007011","url":null,"abstract":"The dairy industry is one of the main sources of agro-industrial wastewater [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78356244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007006
M. Constantin, I. Răut, A. Gurban, G. Vasilescu, M. Doni, N. Radu, E. Alexandrescu, L. Jecu
Introduction: For sustainable agriculture, an attempt has been made to reduce the use of fertilizers and agrochemicals, replacing them instead with biostimulants as viable alternatives [...]
{"title":"Exploring the Potential of Beneficial Paecilomyces to Improve Plant Growth","authors":"M. Constantin, I. Răut, A. Gurban, G. Vasilescu, M. Doni, N. Radu, E. Alexandrescu, L. Jecu","doi":"10.3390/chemproc2022007006","DOIUrl":"https://doi.org/10.3390/chemproc2022007006","url":null,"abstract":"Introduction: For sustainable agriculture, an attempt has been made to reduce the use of fertilizers and agrochemicals, replacing them instead with biostimulants as viable alternatives [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85263871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007002
I. Răut, M. Constantin, E. Alexandrescu, C. Ninciuleanu, M. Raduly, A. Gurban, M. Doni, I. Petre, C. Nicolae, N. Radu, G. Vasilescu, L. Jecu
Concrete is the most used construction material, but its industrial production from lime consumes 2–3% of the global energy demand, generating 0 [...]
混凝土是最常用的建筑材料,但其工业生产中的石灰消耗了全球能源需求的2-3%,产生的能源为零[…]
{"title":"Use of Bacterial Carbonatogenesis for Construction Materials","authors":"I. Răut, M. Constantin, E. Alexandrescu, C. Ninciuleanu, M. Raduly, A. Gurban, M. Doni, I. Petre, C. Nicolae, N. Radu, G. Vasilescu, L. Jecu","doi":"10.3390/chemproc2022007002","DOIUrl":"https://doi.org/10.3390/chemproc2022007002","url":null,"abstract":"Concrete is the most used construction material, but its industrial production from lime consumes 2–3% of the global energy demand, generating 0 [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85310022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007008
Georgica Pandelea (Voicu), D. Ștefan, M. Călinescu, I. Mazilu, Camelia Ungureanu
Introduction: This paper presents the preliminary results of a study that aims to emphasize the compost effect, when used as fertilizer, in Aronia melanocarpa crops [...]
摘要:本文介绍了一项研究的初步结果,该研究旨在强调作为肥料使用在黑果野樱草作物中的堆肥效应[…]
{"title":"The Benefits of Applying Compost in Agriculture as Aronia Crops Fertilizer","authors":"Georgica Pandelea (Voicu), D. Ștefan, M. Călinescu, I. Mazilu, Camelia Ungureanu","doi":"10.3390/chemproc2022007008","DOIUrl":"https://doi.org/10.3390/chemproc2022007008","url":null,"abstract":"Introduction: This paper presents the preliminary results of a study that aims to emphasize the compost effect, when used as fertilizer, in Aronia melanocarpa crops [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83270403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007005
Ioana Tabrea, A. Stefaniu, L. Pirvu, G. Sãvoiu
In the last few years, a new concept of functional foods has been developed, leading to the diversification of food production [...]
在过去的几年里,功能性食品的新概念已经发展起来,导致食品生产的多样化[…]
{"title":"Molecular Design of Functional Ingredients Starting from Natural Bioactive Compounds","authors":"Ioana Tabrea, A. Stefaniu, L. Pirvu, G. Sãvoiu","doi":"10.3390/chemproc2022007005","DOIUrl":"https://doi.org/10.3390/chemproc2022007005","url":null,"abstract":"In the last few years, a new concept of functional foods has been developed, leading to the diversification of food production [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85113767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-28DOI: 10.3390/chemproc2022007001
D. Pasarin, Camelia Rovinaru, C. Matei
The germination process of whole seeds activates and multiplies the composition of amino acids, antioxidants, vitamins, proteins, enzymes, and sugars, and decreases phytate and protease inhibitors concentrations. Furthermore, germination contributes to the improved digestibility of plant proteins; conversion of carbohydrates to simpler forms for easy assimilation; bioavailability of minerals; freeing up of minerals for absorption; and an increase of beneficial enzymes. The aim of this paper was to perform the extraction of alfalfa germinated seeds using conventional and modern methods for the purpose of physical-chemical characterization. The extraction of germinated seeds was carried out by several methods, namely conventional (hydro-alcoholic and autoclave extraction) and modern (ultrasound-assisted extraction) methods. For each method, the following parameters have been set: solvent/substrate ratio, temperature, and reaction time. Hydro-alcoholic extraction was performed according to the method described by Piantino et al. (2008) with minor modifications [1]. The parameters were as follows: ethanol:water ratio 70:30 v/v, reaction time 24 h, at room temperature, and stirred at 150 rpm. Autoclave extraction was performed according to the method described by Maurizio D’Auria (2021) using parameters temperature (121 °C), pressure (1 bar), and reaction time (15 min) [2]. Ultrasound-assisted extraction carried out according to the method described by Ahmad and Shehta (2020) with modifications [3]. The parameters were as follows: 70% ethanol, substrat:solvent ratio 1:10, reaction time 10, 20, 30 min, at room temperature in an ultrasonic bath. The proximate chemical composition analysis for each extract was performed, which refers to water content, total nitrogen, crude protein, carbohydrates, ash, and both macro and micro elements using standard methods. Following the comparative analysis of the preliminary results obtained for the four extracts, the modern method ultrasound-assisted extraction was selected. The mean percentage of chemical compounds was: moisture (at 105 °C) 78.2 ± 0.48%, crude protein 23 ± 1%, and ash (at 550 °C) 3.09 ± 0.004%. The preliminary chemical analysis of the extracts served as the basis for the selection of the extraction method. Conventional methods require a long time for extraction and use solvents at high costs. The interest in using modern methods for the extraction of germinated seeds is growing due to reduced reaction time and solvent volume involved and the accuracy of results obtained.
整个种子的萌发过程激活并增加了氨基酸、抗氧化剂、维生素、蛋白质、酶和糖的组成,并降低了植酸盐和蛋白酶抑制剂的浓度。此外,发芽有助于提高植物蛋白的消化率;将碳水化合物转化为易于吸收的简单形式;矿物质的生物利用度;释放矿物质以供吸收的;以及有益酶的增加。本文采用传统方法和现代方法对紫花苜蓿发芽种子进行提取,并对其进行理化性质表征。发芽种子的提取有几种方法,即传统的(水酒精和高压灭菌法)和现代的(超声辅助提取)方法。对于每种方法,设置了以下参数:溶剂/底物比,温度和反应时间。根据Piantino et al.(2008)描述的方法进行氢醇提取,并进行了少量修改[1]。参数为:乙醇:水比70:30 v/v,反应时间24 h,室温,搅拌转速150 rpm。根据Maurizio D 'Auria(2021)描述的方法,使用温度(121°C)、压力(1 bar)和反应时间(15 min)参数进行蒸压罐提取[2]。超声辅助提取按照Ahmad and Shehta(2020)的方法进行,并进行了修改[3]。实验参数为:70%乙醇,底物与溶剂比1:10,反应时间10、20、30 min,室温超声浴。对每种提取物进行近似化学成分分析,即采用标准方法测定含水量、总氮、粗蛋白质、碳水化合物、灰分以及宏量元素和微量元素。通过对四种提取物初步提取结果的对比分析,选择超声辅助提取的现代方法。化学成分的平均百分比为:水分(105℃)78.2±0.48%,粗蛋白23±1%,灰分(550℃)3.09±0.004%。对提取液进行初步化学分析,为提取方法的选择提供依据。传统的方法需要较长的提取时间和较高的溶剂成本。使用现代方法提取发芽种子的兴趣正在增长,因为减少了反应时间和所涉及的溶剂体积以及所获得的结果的准确性。
{"title":"Extraction of Germinated Seeds by Conventional and Modern Methods","authors":"D. Pasarin, Camelia Rovinaru, C. Matei","doi":"10.3390/chemproc2022007001","DOIUrl":"https://doi.org/10.3390/chemproc2022007001","url":null,"abstract":"The germination process of whole seeds activates and multiplies the composition of amino acids, antioxidants, vitamins, proteins, enzymes, and sugars, and decreases phytate and protease inhibitors concentrations. Furthermore, germination contributes to the improved digestibility of plant proteins; conversion of carbohydrates to simpler forms for easy assimilation; bioavailability of minerals; freeing up of minerals for absorption; and an increase of beneficial enzymes. The aim of this paper was to perform the extraction of alfalfa germinated seeds using conventional and modern methods for the purpose of physical-chemical characterization. The extraction of germinated seeds was carried out by several methods, namely conventional (hydro-alcoholic and autoclave extraction) and modern (ultrasound-assisted extraction) methods. For each method, the following parameters have been set: solvent/substrate ratio, temperature, and reaction time. Hydro-alcoholic extraction was performed according to the method described by Piantino et al. (2008) with minor modifications [1]. The parameters were as follows: ethanol:water ratio 70:30 v/v, reaction time 24 h, at room temperature, and stirred at 150 rpm. Autoclave extraction was performed according to the method described by Maurizio D’Auria (2021) using parameters temperature (121 °C), pressure (1 bar), and reaction time (15 min) [2]. Ultrasound-assisted extraction carried out according to the method described by Ahmad and Shehta (2020) with modifications [3]. The parameters were as follows: 70% ethanol, substrat:solvent ratio 1:10, reaction time 10, 20, 30 min, at room temperature in an ultrasonic bath. The proximate chemical composition analysis for each extract was performed, which refers to water content, total nitrogen, crude protein, carbohydrates, ash, and both macro and micro elements using standard methods. Following the comparative analysis of the preliminary results obtained for the four extracts, the modern method ultrasound-assisted extraction was selected. The mean percentage of chemical compounds was: moisture (at 105 °C) 78.2 ± 0.48%, crude protein 23 ± 1%, and ash (at 550 °C) 3.09 ± 0.004%. The preliminary chemical analysis of the extracts served as the basis for the selection of the extraction method. Conventional methods require a long time for extraction and use solvents at high costs. The interest in using modern methods for the extraction of germinated seeds is growing due to reduced reaction time and solvent volume involved and the accuracy of results obtained.","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73961617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Computational Study to Identify Some Potential Inhibitors of SARS-CoV-2 Main Protease from Biological Active Quinolones","authors":"L. Pintilie","doi":"10.3390/chemproc2022007010","DOIUrl":"https://doi.org/10.3390/chemproc2022007010","url":null,"abstract":"The coronavirus pandemic, known as COVID-19, is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [...]","PeriodicalId":9815,"journal":{"name":"Chemistry Proceedings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74219605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}