Pub Date : 2022-01-22DOI: 10.37895/2071-8004-2021-25-3-40-46
R. V. Gallyamutdinov, E. Golovneva, Zh. A. Revel-Muroz, I. V. Elovsky
Laser exposure stimulates cell proliferation and tissue repair. Branched-chain amino acids (BCAA) are widely used in sports medicine as a stimulator of anabolic processes. However, there is no evidence of the effect of combined laser and BCAA application on skeletal muscle morphometric characteristics during exercise in the training process.Purpose: to study the effect of infrared laser exposure in combination with amino acid at myosatellitocytes and skeletal muscle myocytes during swimming training.Material and methods. The experiment was conducted on 30 Wistar rats: Group 1 – intact, Group 2 – dynamic control (trainings with endurance swimming), Group 3 – trainings and BCAA, Group 4 – trainings and laser exposure at hip muscles (970 nm, 1 W, 60 s), Group 5 – combined exposure to laser and BCAA. Trainings were three times a week for 6 weeks; laser session was after each training. Samples of the bipedal thigh muscle were fixed with formalin; histological sections were stained with hematoxylin-eosin. The morphometric analysis of the digital image of objects with statistical processing by Mann – Whitney method was made.Results. Laser exposure combined with BCAA during trainings increased the nuclei area and the number of myosatellites and myocytes; it also enlarged the cross section of muscle fibers which was more pronounced if to compare with isolated laser irradiation of the muscle or BCAA.Conclusions. Infrared laser exposure in combination with branched-chain amino acids effectively stimulates regeneration due to hyperplasia and hypertrophy of skeletal muscular tissue, thus providing physiological adaptation in the training process.
{"title":"Infrared laser exposure in combination with branchedchain amino acid stimulates physiological adaptation of skeletal muscles","authors":"R. V. Gallyamutdinov, E. Golovneva, Zh. A. Revel-Muroz, I. V. Elovsky","doi":"10.37895/2071-8004-2021-25-3-40-46","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-40-46","url":null,"abstract":"Laser exposure stimulates cell proliferation and tissue repair. Branched-chain amino acids (BCAA) are widely used in sports medicine as a stimulator of anabolic processes. However, there is no evidence of the effect of combined laser and BCAA application on skeletal muscle morphometric characteristics during exercise in the training process.Purpose: to study the effect of infrared laser exposure in combination with amino acid at myosatellitocytes and skeletal muscle myocytes during swimming training.Material and methods. The experiment was conducted on 30 Wistar rats: Group 1 – intact, Group 2 – dynamic control (trainings with endurance swimming), Group 3 – trainings and BCAA, Group 4 – trainings and laser exposure at hip muscles (970 nm, 1 W, 60 s), Group 5 – combined exposure to laser and BCAA. Trainings were three times a week for 6 weeks; laser session was after each training. Samples of the bipedal thigh muscle were fixed with formalin; histological sections were stained with hematoxylin-eosin. The morphometric analysis of the digital image of objects with statistical processing by Mann – Whitney method was made.Results. Laser exposure combined with BCAA during trainings increased the nuclei area and the number of myosatellites and myocytes; it also enlarged the cross section of muscle fibers which was more pronounced if to compare with isolated laser irradiation of the muscle or BCAA.Conclusions. Infrared laser exposure in combination with branched-chain amino acids effectively stimulates regeneration due to hyperplasia and hypertrophy of skeletal muscular tissue, thus providing physiological adaptation in the training process.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"360 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86802995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-21DOI: 10.37895/2071-8004-2021-25-3-21-28
Y. Y. Gorchak, G. Guens, E. Prazdnikov, M. L. Stakhanov, D. Reshetov, D. Khlanta
Purpose: to evaluate the effectiveness of low-level laser radiation in the complex rehabilitation of patients with head and neck tumors after radical surgical treatment as well as to assess the influence of the discussed treatment on the quality of their life.Material and methods. 134 patients with head and neck cancer aged 23–78 years (mean age – 54.24 ± 12.7 years ) were taken into the study. There were 39 (29.1 %) men and 95 (70.9 %) women. All patients were divided into three groups. In Group 1 (n = 45), patients received traditional rehabilitation treatment (physical exercises, massage, medication); in Group 2 (n = 45), patients had a course of traditional rehabilitation plus low-level laser therapy (LLLT); in Group 3 (n = 44), patients had only several LLLT courses as rehabilitation therapy. For laser therapy, laser device “Azor 2K-02” (laser hazard of class II, GOST 12.1.040-83) was used.Results. During the treatment, most of the patients noted early disappearance or noticeable decrease in pain and numbness intensity at the site of the surgical; skin sensitivity and increase of the muscular tone in the shoulder girdle and upper limb at the site of the surgical were restored as well. The most pronounced regression of complaints after rehabilitation therapy was observed in patients who had LLLT in combination with other rehabilitative measures.Conclusion. Radical surgical or combined treatment of patients with malignant tumors of head and neck causes functional disorders of tissues and organs at the site of treatment. Rehabilitation therapy with LLLT in red and/or infrared spectrum range ensures adequate restoration of impaired functions what improves the quality of life of such patients.
{"title":"Low-intensity laser irradiation in the rehabilitation of patients after radical surgical or combined treatment for head and neck tumors","authors":"Y. Y. Gorchak, G. Guens, E. Prazdnikov, M. L. Stakhanov, D. Reshetov, D. Khlanta","doi":"10.37895/2071-8004-2021-25-3-21-28","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-21-28","url":null,"abstract":"Purpose: to evaluate the effectiveness of low-level laser radiation in the complex rehabilitation of patients with head and neck tumors after radical surgical treatment as well as to assess the influence of the discussed treatment on the quality of their life.Material and methods. 134 patients with head and neck cancer aged 23–78 years (mean age – 54.24 ± 12.7 years ) were taken into the study. There were 39 (29.1 %) men and 95 (70.9 %) women. All patients were divided into three groups. In Group 1 (n = 45), patients received traditional rehabilitation treatment (physical exercises, massage, medication); in Group 2 (n = 45), patients had a course of traditional rehabilitation plus low-level laser therapy (LLLT); in Group 3 (n = 44), patients had only several LLLT courses as rehabilitation therapy. For laser therapy, laser device “Azor 2K-02” (laser hazard of class II, GOST 12.1.040-83) was used.Results. During the treatment, most of the patients noted early disappearance or noticeable decrease in pain and numbness intensity at the site of the surgical; skin sensitivity and increase of the muscular tone in the shoulder girdle and upper limb at the site of the surgical were restored as well. The most pronounced regression of complaints after rehabilitation therapy was observed in patients who had LLLT in combination with other rehabilitative measures.Conclusion. Radical surgical or combined treatment of patients with malignant tumors of head and neck causes functional disorders of tissues and organs at the site of treatment. Rehabilitation therapy with LLLT in red and/or infrared spectrum range ensures adequate restoration of impaired functions what improves the quality of life of such patients.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"72 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77179970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-21DOI: 10.37895/2071-8004-2021-25-3-15-20
V. Duvansky, M. M. Musaev, M. M. Gutop
Purpose. To assess the degree of disorders in regional microcirculation in patients with decompensated forms of chronic venous insufficiency of lower extremities and potentials for their correction with low-level laser therapy (LLLT).Material and methods. The authors analyzed results of examination and treatment of 66 patients with decompensated forms of chronic venous insufficiency in their lower extremities. 34 (51.5 %) patients, in addition to traditional therapy, had laser stimulation of microcirculation. For laser irradiation, infrared laser device “Mustang” (wavelength – 0.89 μm, frequency – 80 Hz, power – 10 W, exposure – 2 min per zone) was used. In laser course, there were 10 sessions. The state of microcirculation in tissues was examined with a computerized capillaroscope, a laser analyzer of capillary blood flow and a gas analyzer.Results. Microcirculation in patients with chronic venous insufficiency C6 has its specific features which, by findings of computerized capillaroscope, are manifested with deep suppression of tissue blood flow: namely, expressed polymorphism of capillary structures, violation of sizeratio of capillary sections, increased venous section, decreased density of the capillary network by 1.8 times, increased pericapillary zone by 1.47 times , decreased speed of capillary blood flow in the arterial section by 10.5 times and in the venous section by 11.5 times.Conclusion. Patients with decompensated forms of chronic venous insufficiency in lower extremities were observed to have significant morphological and functional changes in microcirculation, including structural changes in microvessels, decreased density of capillary network, increased prevascular zone, decreased speed of capillary blood flow. As a result, these changes cause disorders in tissue trophism, progressive decrease in TcpO2 and development of trophic ulcers. Low-level laser stimulation of microcirculation in the complex treatment of patients with decompensated forms of chronic venous insufficiency activates transcapillary metabolism, helps to restore structures and functions of microvasculature by increasing the myogenic activity of smooth muscle cells of arterioles and precapillaries as well as by normalizing arterio-venous relationships what accelerates tissue granulation and ulcer epithelialization.
{"title":"Laser technologies in the diagnostics and care of patients with decompensated forms of chronic venous insufficiency in the lower extremities","authors":"V. Duvansky, M. M. Musaev, M. M. Gutop","doi":"10.37895/2071-8004-2021-25-3-15-20","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-15-20","url":null,"abstract":"Purpose. To assess the degree of disorders in regional microcirculation in patients with decompensated forms of chronic venous insufficiency of lower extremities and potentials for their correction with low-level laser therapy (LLLT).Material and methods. The authors analyzed results of examination and treatment of 66 patients with decompensated forms of chronic venous insufficiency in their lower extremities. 34 (51.5 %) patients, in addition to traditional therapy, had laser stimulation of microcirculation. For laser irradiation, infrared laser device “Mustang” (wavelength – 0.89 μm, frequency – 80 Hz, power – 10 W, exposure – 2 min per zone) was used. In laser course, there were 10 sessions. The state of microcirculation in tissues was examined with a computerized capillaroscope, a laser analyzer of capillary blood flow and a gas analyzer.Results. Microcirculation in patients with chronic venous insufficiency C6 has its specific features which, by findings of computerized capillaroscope, are manifested with deep suppression of tissue blood flow: namely, expressed polymorphism of capillary structures, violation of sizeratio of capillary sections, increased venous section, decreased density of the capillary network by 1.8 times, increased pericapillary zone by 1.47 times , decreased speed of capillary blood flow in the arterial section by 10.5 times and in the venous section by 11.5 times.Conclusion. Patients with decompensated forms of chronic venous insufficiency in lower extremities were observed to have significant morphological and functional changes in microcirculation, including structural changes in microvessels, decreased density of capillary network, increased prevascular zone, decreased speed of capillary blood flow. As a result, these changes cause disorders in tissue trophism, progressive decrease in TcpO2 and development of trophic ulcers. Low-level laser stimulation of microcirculation in the complex treatment of patients with decompensated forms of chronic venous insufficiency activates transcapillary metabolism, helps to restore structures and functions of microvasculature by increasing the myogenic activity of smooth muscle cells of arterioles and precapillaries as well as by normalizing arterio-venous relationships what accelerates tissue granulation and ulcer epithelialization.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86565014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-21DOI: 10.37895/2071-8004-2021-25-3-8-14
V. Zhukov, A. Kozhin, V. Popova
Introduction. Increasing concentrations of xenobiotics in the biosphere have induced the growth of microelementoses. The pathology is frequent among children as a result of their adaptive insufficiency calling forth a decrease of nonspecific resistance. These tendencies make increasingly urgent the need for development of more efficient ways to correct environmentally determined conditions.Purpose: a comparative study of immunobiochemical and elemental status of sickly children from environmentally vulnerable population groups in order to expose the exact etiology for decreasing nonspecific resistance and to develop a combined therapy system for their rehabilitation.Materials and methods. Children from environmentally vulnerable population groups were the object of research. Enzyme immunoassay methods were used to examine the levels of hormones, blood chemistry values, and immunoglobulins. Atomic absorption was employed to determine the concentration of chemical elements in the urine. Nutrients and low-level laser radiation were used for rehabilitation of the children.Results and discussion. Children with sharply decreased nonspecific resistance were found to belong to sickly children category. They had microelementoses of technogenic origin. Rehabilitative therapy for sickly children was more efficient in case of combined application of nutrients and low-level laser radiation.Conclusion. The performed study demonstrates that rehabilitation of sickly children from environmentally vulnerable population groups would benefit from addition of laser therapy.
{"title":"Laser therapy in rehabilitation of children from environmentally vulnerable population groups","authors":"V. Zhukov, A. Kozhin, V. Popova","doi":"10.37895/2071-8004-2021-25-3-8-14","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-3-8-14","url":null,"abstract":"Introduction. Increasing concentrations of xenobiotics in the biosphere have induced the growth of microelementoses. The pathology is frequent among children as a result of their adaptive insufficiency calling forth a decrease of nonspecific resistance. These tendencies make increasingly urgent the need for development of more efficient ways to correct environmentally determined conditions.Purpose: a comparative study of immunobiochemical and elemental status of sickly children from environmentally vulnerable population groups in order to expose the exact etiology for decreasing nonspecific resistance and to develop a combined therapy system for their rehabilitation.Materials and methods. Children from environmentally vulnerable population groups were the object of research. Enzyme immunoassay methods were used to examine the levels of hormones, blood chemistry values, and immunoglobulins. Atomic absorption was employed to determine the concentration of chemical elements in the urine. Nutrients and low-level laser radiation were used for rehabilitation of the children.Results and discussion. Children with sharply decreased nonspecific resistance were found to belong to sickly children category. They had microelementoses of technogenic origin. Rehabilitative therapy for sickly children was more efficient in case of combined application of nutrients and low-level laser radiation.Conclusion. The performed study demonstrates that rehabilitation of sickly children from environmentally vulnerable population groups would benefit from addition of laser therapy.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81648682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-27DOI: 10.37895/2071-8004-2021-25-2-75-76
A. Editorial
.
．
{"title":"Congratulations on the anniversary of G.E. Brill","authors":"A. Editorial","doi":"10.37895/2071-8004-2021-25-2-75-76","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-2-75-76","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75953703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-27DOI: 10.37895/2071-8004-2021-25-2-9-15
N. Streltsova, A. P. Vasiliev
Purpose: to estimate the anti-anginal effect and to assess changes in hemodynamic parameters in patients with angina pectoris (AP) under low-intensive laser irradiation and to compare them with those under Obsidan preparation administration.Materials and methods. 70 males with AP of functional class I–IV were enrolled in the study and randomized into 2 equivalent groups: Group 1 – patients who took Obsidan; Group 2 — patients who were treated with infrared laser light. Patients were examined at the initial stage-one hour after 40 mg Obsidan take (Group 1), and one month after 10-day course of laser therapy (LT) (Group 2). All patients had echocardiography and cycle ergometric test.Results. The performed examinations showed a statistically significant increase in exercise tolerance in patients of LT group and Obsidan group by 35.0% and 34.1%, respectively. It should be noted that echocardiographic indicators had unidirectional, statistically significant shifts characterized by improvements in the myocardial inotropic function: decrease in the end-systolic volume by 17.9% and 18.8%, increase in the left ventricular ejection fraction from 50.3 ± 6.2 to 55.7 ± 5.8% and from 46.3 ± 4.3 to 50.1 ± 6.1 after LT and Obsidan , respectively. The optimal diastolic cardiac function was confirmed by the reduced time of myocardium isometric relaxation from 112.9 ± 24.3 to 94.3 ± 25.3 ms (p=0.012) under LT and from 110.3 ± 22.7 to 97.3 ± 19.3 ms under Obsidan (p=0.012). Results of the exercise tolerance test indicated the activation of cardiac economy mechanisms in both groups.Conclusion. Low-intensive LT had an impact at the cardiac activity similar to that of Obsidan. Moreover, it also has the equal anti-ischemic effect what may be explained by the decrease of energy expenditure during physical activity in patients with AP.
目的:评价低强度激光照射下心绞痛(AP)患者的抗心绞痛效果和血流动力学参数的变化，并与奥比sidan制剂组进行比较。材料和方法。70例功能性I-IV级AP男性患者纳入研究，随机分为2个等效组:1组-服用奥比司丹的患者;第二组:采用红外激光治疗。患者在初始阶段-服用40mg奥比司丹后1小时(第一组)和10天激光治疗(LT)后1个月(第二组)进行检查。所有患者均进行超声心动图和周期几何测试。经检查显示，LT组和奥比丹组患者运动耐量分别提高了35.0%和34.1%，具有统计学意义。值得注意的是，超声心动图指标有单向的、有统计学意义的变化，其特征是心肌肌力功能的改善:LT和Obsidan后，收缩末期容积下降17.9%和18.8%，左室射血分数分别从50.3±6.2增加到55.7±5.8%，从46.3±4.3增加到50.1±6.1。心肌等长舒张时间由LT组的112.9±24.3 ms缩短至94.3±25.3 ms (p=0.012)，奥比司丹组的110.3±22.7 ms缩短至97.3±19.3 ms (p=0.012)。运动耐量试验结果表明，两组大鼠心脏经济机制均被激活。低强度肝移植对心脏活动的影响与奥比旦相似。此外，它还具有同样的抗缺血作用，这可能是由于AP患者在体力活动期间能量消耗减少所致。
{"title":"Anti-ischemic effect and cardiodynamic changes under low-intensive laser irradiation compared to the obsidan effect in patients with angina pectoris","authors":"N. Streltsova, A. P. Vasiliev","doi":"10.37895/2071-8004-2021-25-2-9-15","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-2-9-15","url":null,"abstract":"Purpose: to estimate the anti-anginal effect and to assess changes in hemodynamic parameters in patients with angina pectoris (AP) under low-intensive laser irradiation and to compare them with those under Obsidan preparation administration.Materials and methods. 70 males with AP of functional class I–IV were enrolled in the study and randomized into 2 equivalent groups: Group 1 – patients who took Obsidan; Group 2 — patients who were treated with infrared laser light. Patients were examined at the initial stage-one hour after 40 mg Obsidan take (Group 1), and one month after 10-day course of laser therapy (LT) (Group 2). All patients had echocardiography and cycle ergometric test.Results. The performed examinations showed a statistically significant increase in exercise tolerance in patients of LT group and Obsidan group by 35.0% and 34.1%, respectively. It should be noted that echocardiographic indicators had unidirectional, statistically significant shifts characterized by improvements in the myocardial inotropic function: decrease in the end-systolic volume by 17.9% and 18.8%, increase in the left ventricular ejection fraction from 50.3 ± 6.2 to 55.7 ± 5.8% and from 46.3 ± 4.3 to 50.1 ± 6.1 after LT and Obsidan , respectively. The optimal diastolic cardiac function was confirmed by the reduced time of myocardium isometric relaxation from 112.9 ± 24.3 to 94.3 ± 25.3 ms (p=0.012) under LT and from 110.3 ± 22.7 to 97.3 ± 19.3 ms under Obsidan (p=0.012). Results of the exercise tolerance test indicated the activation of cardiac economy mechanisms in both groups.Conclusion. Low-intensive LT had an impact at the cardiac activity similar to that of Obsidan. Moreover, it also has the equal anti-ischemic effect what may be explained by the decrease of energy expenditure during physical activity in patients with AP.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85913333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-27DOI: 10.37895/2071-8004-2021-25-2-28-40
Y. Chepurnaya, G. Melkonyan, N. T. Gulmuradova, A. A. Sorokin
Despite the evolution in modern surgery and in pharmaceutical industry, purulent pathology of the hand is occupying a leading position for many years among all diseases with which patients are admitted to hospitals. Over the years, medical care for such patients has been improving. A high social and economic significance of this problem makes surgeons to continue searches of new directions not only in surgical techniques, but also in postoperative wound management to improve outcomes in patients with purulent diseases of the hand.The purpose of this work is to assess results of care of patients with purulent finger and hand diseases treated with laser light necrectomy and photodynamic therapy. A comparative analysis of wound process dynamics and treatment outcomes in 198 patients with hand purulent diseases who had been admitted to Moscow City Hospital No. 4 was made by the authors. All patients were divided into four groups depending on the curative modality. In Group 1 (n = 53), a wound was sutured after surgery, and a drainage-lavage system (DLS) was installed; in Group 2 (n = 50), a wound was not sutured because of contraindications to suturing; in Group 3 (n = 46), patients had laser necrectomy after which a wound was sutured and DLS was installed; in Group 4 (n = 49), a wound was not sutured because of contraindications like in Group 2, but it was treated with antiseptic dressings and photodynamic therapy at an early postoperative period. Various aspects of the effectiveness of laser techniques have been analyzed: dynamics of wound healing, changes in wound defect size, level of pain syndrome assessed by VAS, changes in clinical blood tests, changes in wound exudate cytological picture as well as changes in wound microflora. Acceleration of wound healing was noted in all patients who were treated with laser light what, consequently, shortened their inpatient stay. Laser light also changed cytological and microbiological patterns of wound exudate, as evidenced by the decrease of wound detritus and by the decrease of microbial content in the wound. In patients, who were treated with laser light, less pain syndrome was registered immediately after laser technique application.The obtained findings demonstrate a positive effect of laser necrectomy with DLS at wound process as well. Photodynamic therapy significantly improved results in patients with open wound management on the hand and fingers. Laser techniques have good perspectives in purulent surgery of the hand.
{"title":"Improving the results of treatment of patients with purulent diseases of fingers and hands using laser irradiation and photodynamic therapy","authors":"Y. Chepurnaya, G. Melkonyan, N. T. Gulmuradova, A. A. Sorokin","doi":"10.37895/2071-8004-2021-25-2-28-40","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-2-28-40","url":null,"abstract":"Despite the evolution in modern surgery and in pharmaceutical industry, purulent pathology of the hand is occupying a leading position for many years among all diseases with which patients are admitted to hospitals. Over the years, medical care for such patients has been improving. A high social and economic significance of this problem makes surgeons to continue searches of new directions not only in surgical techniques, but also in postoperative wound management to improve outcomes in patients with purulent diseases of the hand.The purpose of this work is to assess results of care of patients with purulent finger and hand diseases treated with laser light necrectomy and photodynamic therapy. A comparative analysis of wound process dynamics and treatment outcomes in 198 patients with hand purulent diseases who had been admitted to Moscow City Hospital No. 4 was made by the authors. All patients were divided into four groups depending on the curative modality. In Group 1 (n = 53), a wound was sutured after surgery, and a drainage-lavage system (DLS) was installed; in Group 2 (n = 50), a wound was not sutured because of contraindications to suturing; in Group 3 (n = 46), patients had laser necrectomy after which a wound was sutured and DLS was installed; in Group 4 (n = 49), a wound was not sutured because of contraindications like in Group 2, but it was treated with antiseptic dressings and photodynamic therapy at an early postoperative period. Various aspects of the effectiveness of laser techniques have been analyzed: dynamics of wound healing, changes in wound defect size, level of pain syndrome assessed by VAS, changes in clinical blood tests, changes in wound exudate cytological picture as well as changes in wound microflora. Acceleration of wound healing was noted in all patients who were treated with laser light what, consequently, shortened their inpatient stay. Laser light also changed cytological and microbiological patterns of wound exudate, as evidenced by the decrease of wound detritus and by the decrease of microbial content in the wound. In patients, who were treated with laser light, less pain syndrome was registered immediately after laser technique application.The obtained findings demonstrate a positive effect of laser necrectomy with DLS at wound process as well. Photodynamic therapy significantly improved results in patients with open wound management on the hand and fingers. Laser techniques have good perspectives in purulent surgery of the hand.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86155765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-27DOI: 10.37895/2071-8004-2021-25-2-16-21
Yu. G. Pak, N. Kalyagina, D. M. Yagudaev
Introduction. This work analyzes efficacy, convenience, and safety of a high-energy laser light technique for destructing large kidney stones in patients with nephrolithiasis in comparison to other contact methods of nephrolithotripsy.Material and methods. The effectiveness of contact laser nephrolithotripsy is compared to that of hydropneumatic and ultrasonic lithotripsy. Holmium green laser light was used in this laser procedure. For other techniques, Swiss LithoClast Master devices were used. The authors have analyzed outcomes obtained after operating on 73 patients with large and complex kidney stones.Results. To evaluate the effectiveness, basic parameters were taken (degree of kidney cleaning of stones and their fragments, probability of migration of stone fragments, blood loss, duration of surgery, complications, etc.). In addition, the correlation between basic parameters was obtained and analyzed.Conclusion. The present trial has shown that laser contact lithotripsy is the most optimal technique for destructing large and complex kidney stones in comparison to traditional modalities such as contact hydropneumatic and ultrasonic lithotripsy. It takes more time but provides more effective cleaning from calculi.
{"title":"Effectiveness of high-intensity laser light for treating large kidney stones","authors":"Yu. G. Pak, N. Kalyagina, D. M. Yagudaev","doi":"10.37895/2071-8004-2021-25-2-16-21","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-2-16-21","url":null,"abstract":"Introduction. This work analyzes efficacy, convenience, and safety of a high-energy laser light technique for destructing large kidney stones in patients with nephrolithiasis in comparison to other contact methods of nephrolithotripsy.Material and methods. The effectiveness of contact laser nephrolithotripsy is compared to that of hydropneumatic and ultrasonic lithotripsy. Holmium green laser light was used in this laser procedure. For other techniques, Swiss LithoClast Master devices were used. The authors have analyzed outcomes obtained after operating on 73 patients with large and complex kidney stones.Results. To evaluate the effectiveness, basic parameters were taken (degree of kidney cleaning of stones and their fragments, probability of migration of stone fragments, blood loss, duration of surgery, complications, etc.). In addition, the correlation between basic parameters was obtained and analyzed.Conclusion. The present trial has shown that laser contact lithotripsy is the most optimal technique for destructing large and complex kidney stones in comparison to traditional modalities such as contact hydropneumatic and ultrasonic lithotripsy. It takes more time but provides more effective cleaning from calculi.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78371094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-27DOI: 10.37895/2071-8004-2021-25-2-63-74
V. P. Minaev
The article presents a review on laser medical equipment and laser medical technologies developed for this equipment which have appeared for the last ten years.
本文综述了近十年来出现的激光医疗设备及其相关的激光医疗技术。
{"title":"2011-2021 – Ten more years of development of laser medical equipment and technologies","authors":"V. P. Minaev","doi":"10.37895/2071-8004-2021-25-2-63-74","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-2-63-74","url":null,"abstract":"The article presents a review on laser medical equipment and laser medical technologies developed for this equipment which have appeared for the last ten years.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76707465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-27DOI: 10.37895/2071-8004-2021-25-2-48-54
V. Lazarenko, Y. V. Kanishchev, P. M. Nazarenko, D. P. Nazarenko, T. A. Samgina, A. Loktionov, S. M. Gorbunov
Objective. The radical elimination of extrahepatic biliary tract pathology in choledocholithiasis and acute biliary pancreatitis (ABP) reduces the risk of infection and eliminates the source of endogenous intoxication; so, the search of safe and effective techniques for endoscopic papillosphincterotomy (EPT) is important.Purpose: to assess outcomes of laser-assisted endoscopic papillosphincterotomy.Material and methods. 288 patients with “wedged” (n = 111) and “valve” (n = 177) choledocholithiasis and acute biliary pancreatitis were divided into two groups depending on EPT technique: in the control group, a papillotome with electrocoagulation cord was used (n = 195); in the main group, laser scalpel was used (n = 93).Results. 87 patients with “wedged” choledocholithiasis were treated with EPT and an end electrode on the wedged stone. 16 patients out of them had mild bleeding which was stopped by irrigation with epinephrine solution (1 : 10 000) followed by the targeted coagulation. The average surgical time was 38 ± 16 min. In 24 patients with rigid and edematous medial wall of the duodenum due to acute biliary pancreatitis, the proposed device plus laser technique for papillosphincterotomy were used (patent of the Russian Federation No. 2614891). There was no bleeding, the average surgical time was 24 ± 12 min. In “valve” choledocholithiasis, laparoscopic cholecystectomy (LCE) was performed; calculi from the common bile duct were removed. In 108 patients during LCE, EPT was made via an antegrade catheter. In 69 patients with anatomical and physiological obstacles caused by the major duodenal papilla, we performed LCE and EPT with laser light via an antegrade guide light made of fluoroplastics (patent of the Russian Federation No. 41594). Concrements from the common bile duct were removed with the Dormia basket.Conclusions. Laser light causes less damage, reliably provides hemostasis along the incision line on the anterior wall of the major duodenal papilla; in addition, a wedged calculus in “wedged” choledocholithiasis and a fluoroplastic light guide in “valve” choledocholithiasis reliably protect the posterior wall of the major duodenal papilla from laser light damage. Laser techniques used in EPT make the treatment of choledocholithiasis in patients with ABP having anatomical and physiological problems due to the major duodenal papilla safe and effective.
{"title":"Laser papillosphincterotomy in choledocholithiasis and acute biliary pancreatitis","authors":"V. Lazarenko, Y. V. Kanishchev, P. M. Nazarenko, D. P. Nazarenko, T. A. Samgina, A. Loktionov, S. M. Gorbunov","doi":"10.37895/2071-8004-2021-25-2-48-54","DOIUrl":"https://doi.org/10.37895/2071-8004-2021-25-2-48-54","url":null,"abstract":"Objective. The radical elimination of extrahepatic biliary tract pathology in choledocholithiasis and acute biliary pancreatitis (ABP) reduces the risk of infection and eliminates the source of endogenous intoxication; so, the search of safe and effective techniques for endoscopic papillosphincterotomy (EPT) is important.Purpose: to assess outcomes of laser-assisted endoscopic papillosphincterotomy.Material and methods. 288 patients with “wedged” (n = 111) and “valve” (n = 177) choledocholithiasis and acute biliary pancreatitis were divided into two groups depending on EPT technique: in the control group, a papillotome with electrocoagulation cord was used (n = 195); in the main group, laser scalpel was used (n = 93).Results. 87 patients with “wedged” choledocholithiasis were treated with EPT and an end electrode on the wedged stone. 16 patients out of them had mild bleeding which was stopped by irrigation with epinephrine solution (1 : 10 000) followed by the targeted coagulation. The average surgical time was 38 ± 16 min. In 24 patients with rigid and edematous medial wall of the duodenum due to acute biliary pancreatitis, the proposed device plus laser technique for papillosphincterotomy were used (patent of the Russian Federation No. 2614891). There was no bleeding, the average surgical time was 24 ± 12 min. In “valve” choledocholithiasis, laparoscopic cholecystectomy (LCE) was performed; calculi from the common bile duct were removed. In 108 patients during LCE, EPT was made via an antegrade catheter. In 69 patients with anatomical and physiological obstacles caused by the major duodenal papilla, we performed LCE and EPT with laser light via an antegrade guide light made of fluoroplastics (patent of the Russian Federation No. 41594). Concrements from the common bile duct were removed with the Dormia basket.Conclusions. Laser light causes less damage, reliably provides hemostasis along the incision line on the anterior wall of the major duodenal papilla; in addition, a wedged calculus in “wedged” choledocholithiasis and a fluoroplastic light guide in “valve” choledocholithiasis reliably protect the posterior wall of the major duodenal papilla from laser light damage. Laser techniques used in EPT make the treatment of choledocholithiasis in patients with ABP having anatomical and physiological problems due to the major duodenal papilla safe and effective.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80863275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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