Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-8-15
A. Editorial
.
．
{"title":"To the centenary of the birth of Oleg Ksenofontovich Skobelkin","authors":"A. Editorial","doi":"10.37895/2071-8004-2023-27-1-8-15","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-8-15","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80441284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-39-45
V. B. Knyazkov, E. Prazdnikov, N. A. Daikhes
Purpose: to study anatomical and physiological features of the soft palate in patients with rhonchopathy and obstructive sleep apnea (OSA) syndrome so as to minimize damage to tissue structures during laser uvulopalatoplasty.Material and methods. Five hundred twenty-three patients with rhonchopathy and OSA syndrome were examined using the index technique for determining neck circumference-height ratio (NHR), pharyngoscopy and endoscopy of the oral and pharyngeal cavities.Results. Obstructive sleep apnea syndrome is more often met in patients having rhonchopathy and the brachymorphic and mesomorphic type of their neck. The researchers have found a clear dependence between the increase in the number of patients having rhonchopathy and moderate and severe obstructive sleep apnea syndrome and the increase of soft palate hypertrophy combined with ptosis. A cone-shaped depression on the anterior surface of the soft palate was noted in 80-90 % of patients with normal weight (body mass index < 25); in 40–60 % of patients with grade I obesity (body mass index – 30–34.9); in 10–15 % of patients with grade II obesity (body mass index – 35–39,9); in patients with grade IIIobesity (body mass index > 40) there were no any depression in the soft palate. Patients with uncomplicated snoring have a thick area in the forma pillow at the back of their soft palate sized 1 × 0.5 × 0.5 cm, while in patients with severe OSA syndrome this «pillow» is up to 2 × 1.5 × 1 cm.Conclusion. The effectiveness of laser uvulopalatoplasty depends not only on the adequate choice of main parameters for laser irradiation, but also on the careful consideration of anatomical and functional features of the soft palate in each operated patient with rhonchopathy and obstructive sleep apnea syndrome.
{"title":"Anatomical and physiological justification of laser sculptural uvulopalatoplasty in rhonchopathy and obstructive sleep apnea syndrome","authors":"V. B. Knyazkov, E. Prazdnikov, N. A. Daikhes","doi":"10.37895/2071-8004-2023-27-1-39-45","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-39-45","url":null,"abstract":"Purpose: to study anatomical and physiological features of the soft palate in patients with rhonchopathy and obstructive sleep apnea (OSA) syndrome so as to minimize damage to tissue structures during laser uvulopalatoplasty.Material and methods. Five hundred twenty-three patients with rhonchopathy and OSA syndrome were examined using the index technique for determining neck circumference-height ratio (NHR), pharyngoscopy and endoscopy of the oral and pharyngeal cavities.Results. Obstructive sleep apnea syndrome is more often met in patients having rhonchopathy and the brachymorphic and mesomorphic type of their neck. The researchers have found a clear dependence between the increase in the number of patients having rhonchopathy and moderate and severe obstructive sleep apnea syndrome and the increase of soft palate hypertrophy combined with ptosis. A cone-shaped depression on the anterior surface of the soft palate was noted in 80-90 % of patients with normal weight (body mass index < 25); in 40–60 % of patients with grade I obesity (body mass index – 30–34.9); in 10–15 % of patients with grade II obesity (body mass index – 35–39,9); in patients with grade IIIobesity (body mass index > 40) there were no any depression in the soft palate. Patients with uncomplicated snoring have a thick area in the forma pillow at the back of their soft palate sized 1 × 0.5 × 0.5 cm, while in patients with severe OSA syndrome this «pillow» is up to 2 × 1.5 × 1 cm.Conclusion. The effectiveness of laser uvulopalatoplasty depends not only on the adequate choice of main parameters for laser irradiation, but also on the careful consideration of anatomical and functional features of the soft palate in each operated patient with rhonchopathy and obstructive sleep apnea syndrome.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75687032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-16-22
Y. Alekseev, V. S. Shiriaev, A. Baranov, A. Khosrovyan, V. Babushkin
Purpose: to develop a technique for therapeutic application of photoactivated photosensitizer «Radachlorin» to be included into the complextherapy of nosocomial pneumonia.Material and methods. Twelve patients with nosocomial pneumonia were taken in the trial. They were treated with a device having a nebulizer witha ring-shaped irradiator and diodes λ ≈ 660 nm for photoactivation of photosensitizer «Radachlorin» (manufactured by OOO «RADA-PHARMA»,Moscow, registration number LS-001868). The photosensitizer was developed according to the technical tasks provided by OOO «New SurgicalTechnologies» (Moscow, Russia). Radachlorin solution photolysis products were inhaled by the patients twice a day for 3 days in combinationwith the standard therapy when they were in ICU. Patients in the control group (n = 12) did not have any inhalations.Results and discussion. On day 3, the number of colony-forming units (CFU) of various pathogens found in swabs from the throat decreasedby 39.45 ± 3.17 % on average; C-reactive protein decreased by 42.38 ± 4.26 %; procalcitonin decreased by 51.83 ± 3.45 %, if to compareto baseline limits. At the same period in the control group, CFU in swabs increased in average by 17.28 ± 4.21 %; C-reactive protein increasedby 27.76 ± 3.52 %; procalcitonin increased by 30.15 ± 2.24 %. On day 10 in the main group, the number of CFU pathogens decreasedby 35.45 ± 3.32 %; C-reactive protein decreased by 72.15 ± 2.56 %; procalcitonin decreased by 55.56 ± 4.23 %, if to compare to baseline limits. On day 10 in the control group, CFU concentration remained elevated by 31.15 ± 2.56 %; C-reactive protein – by 65.32 ± 4.27; procalcitonin – by 30.21 ± 3.45 %, if to compare to baseline values. These findings indicate that the inflammatory process acquired a progressive form which demands switching to other curative modalities and more careful selection of antibiotics. The probability of random origin in statistical processing is p < 0.05. There were no undesirable side effects during procedures.Conclusion. Justified application of the described technique – inhalations of photolysis products of E 6 chloride derivatives – has an effective therapeutic impact at the course of nosocomial pneumonia. It seems promising to continue investigations on the described technique, namely, to search for the most effective ways of its application, to find out an optimal number and frequency of procedures under the control of general clinical and special methods of examination of the studied patients, since the data which have been obtained by the authors us are preliminary and should be supplemented with new findings.
{"title":"Chlorin photosensitizer photolysis products for treating hospital-acquired pneumonia","authors":"Y. Alekseev, V. S. Shiriaev, A. Baranov, A. Khosrovyan, V. Babushkin","doi":"10.37895/2071-8004-2023-27-1-16-22","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-16-22","url":null,"abstract":"Purpose: to develop a technique for therapeutic application of photoactivated photosensitizer «Radachlorin» to be included into the complextherapy of nosocomial pneumonia.Material and methods. Twelve patients with nosocomial pneumonia were taken in the trial. They were treated with a device having a nebulizer witha ring-shaped irradiator and diodes λ ≈ 660 nm for photoactivation of photosensitizer «Radachlorin» (manufactured by OOO «RADA-PHARMA»,Moscow, registration number LS-001868). The photosensitizer was developed according to the technical tasks provided by OOO «New SurgicalTechnologies» (Moscow, Russia). Radachlorin solution photolysis products were inhaled by the patients twice a day for 3 days in combinationwith the standard therapy when they were in ICU. Patients in the control group (n = 12) did not have any inhalations.Results and discussion. On day 3, the number of colony-forming units (CFU) of various pathogens found in swabs from the throat decreasedby 39.45 ± 3.17 % on average; C-reactive protein decreased by 42.38 ± 4.26 %; procalcitonin decreased by 51.83 ± 3.45 %, if to compareto baseline limits. At the same period in the control group, CFU in swabs increased in average by 17.28 ± 4.21 %; C-reactive protein increasedby 27.76 ± 3.52 %; procalcitonin increased by 30.15 ± 2.24 %. On day 10 in the main group, the number of CFU pathogens decreasedby 35.45 ± 3.32 %; C-reactive protein decreased by 72.15 ± 2.56 %; procalcitonin decreased by 55.56 ± 4.23 %, if to compare to baseline limits. On day 10 in the control group, CFU concentration remained elevated by 31.15 ± 2.56 %; C-reactive protein – by 65.32 ± 4.27; procalcitonin – by 30.21 ± 3.45 %, if to compare to baseline values. These findings indicate that the inflammatory process acquired a progressive form which demands switching to other curative modalities and more careful selection of antibiotics. The probability of random origin in statistical processing is p < 0.05. There were no undesirable side effects during procedures.Conclusion. Justified application of the described technique – inhalations of photolysis products of E 6 chloride derivatives – has an effective therapeutic impact at the course of nosocomial pneumonia. It seems promising to continue investigations on the described technique, namely, to search for the most effective ways of its application, to find out an optimal number and frequency of procedures under the control of general clinical and special methods of examination of the studied patients, since the data which have been obtained by the authors us are preliminary and should be supplemented with new findings.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83876134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-46-52
E. N. Lazareva, V. Makashova, E. G. Osipova
The authors present a review of the studies of the effect of pulsed laser light in osteoarthritis depending on its wavelength. Laser radiation with wavelength 600 nm stimulates regeneration of bone tissues; laser light wavelength over 800 nm reduces weakness and atrophy of skeletal muscles with a simultaneous increase of extensor strength and joint mobility. Combination of pulsed laser light of various wavelengths has a marked analgesic effect in anti-inflammatory processes at the postoperative period after endoprosthetic surgery.
{"title":"Laser therapy in osteoarthritis (literature review)","authors":"E. N. Lazareva, V. Makashova, E. G. Osipova","doi":"10.37895/2071-8004-2023-27-1-46-52","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-46-52","url":null,"abstract":"The authors present a review of the studies of the effect of pulsed laser light in osteoarthritis depending on its wavelength. Laser radiation with wavelength 600 nm stimulates regeneration of bone tissues; laser light wavelength over 800 nm reduces weakness and atrophy of skeletal muscles with a simultaneous increase of extensor strength and joint mobility. Combination of pulsed laser light of various wavelengths has a marked analgesic effect in anti-inflammatory processes at the postoperative period after endoprosthetic surgery.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"2005 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78875681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-53-56
N. V. Drozdova, Y. Alekseev, A. A. Lukovkina
Purpose: to describe a clinical case of successful application of light-oxygen therapy (LOT) in a patient with plantar warts.Material and methods. The publication presents a clinical case of the successful outcome after light-oxygen therapy in the absorption spectrum of endogenous oxygen with its transfer to the singlet state in a patient with plantar warts. Russian-made diode laser «Super Seb», manufactured by LLC New Surgical Technologies (Moscow, Russia) with wavelength near 1265 nm, laser power 0–3 W was used as a source of laser light. Radiation power was from 2.1 to 2.7 W. Power density – from 0.86 to 1.86 W/cm2. Exposure dose – from 258 to 558 J/cm2. No anesthesia was required. The maximal surface heating temperature during the procedure was 41 °C. Temperature was controlled with non–contact infrared thermometer ELARI SmartCare model YC-E13 (manufactured by Zhengyang Yuncheng Medical Technology Co. Ltd., China) to eliminate thermal damage. Laser sessions were twice a week with 3–4 day intervals.Results. Complete clinical remission was achieved after 14 LOT sessions.Conclusions. Light-oxygen therapy is an effective and safe procedure for patients with plantar warts.
{"title":"Effectiveness of light-oxygen therapy in plantar warts (clinical observation)","authors":"N. V. Drozdova, Y. Alekseev, A. A. Lukovkina","doi":"10.37895/2071-8004-2023-27-1-53-56","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-53-56","url":null,"abstract":"Purpose: to describe a clinical case of successful application of light-oxygen therapy (LOT) in a patient with plantar warts.Material and methods. The publication presents a clinical case of the successful outcome after light-oxygen therapy in the absorption spectrum of endogenous oxygen with its transfer to the singlet state in a patient with plantar warts. Russian-made diode laser «Super Seb», manufactured by LLC New Surgical Technologies (Moscow, Russia) with wavelength near 1265 nm, laser power 0–3 W was used as a source of laser light. Radiation power was from 2.1 to 2.7 W. Power density – from 0.86 to 1.86 W/cm2. Exposure dose – from 258 to 558 J/cm2. No anesthesia was required. The maximal surface heating temperature during the procedure was 41 °C. Temperature was controlled with non–contact infrared thermometer ELARI SmartCare model YC-E13 (manufactured by Zhengyang Yuncheng Medical Technology Co. Ltd., China) to eliminate thermal damage. Laser sessions were twice a week with 3–4 day intervals.Results. Complete clinical remission was achieved after 14 LOT sessions.Conclusions. Light-oxygen therapy is an effective and safe procedure for patients with plantar warts.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86874553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-34-38
E. A. Leontiev, G. Struchko, V. A. Kozlov, A. L. Fedorov, T. Y. Leontyeva
Purpose: to study the quantitative intensity of optical density and light absorption of the electromagnetic radiation with tattoo pigment aqueous solution depending on its temperature.Material and methods. One hundred twenty-three of the most common commercial tattoo pigments were selected for the trial; 369 samples of aqueous solutions were made of them. Optical density of each pigment sample was determined at 14 and 77 °C. Then, each sample was exposed to optical radiation (IPL xenon lamp with pulsed light) at 14 and 77 °C.Results and discussion. Electromagnetic radiation with wavelengths 532 and 1064 nm increased tattoo pigment destruction from 78,27 to 84,37 % under temperature rise from 14 to 77 °C.Conclusion. Electromagnetic radiation of the optical range with wavelengths 532 and 1064 nm cannot destroy all tattoo pigments; however, optical density of solutions changes under temperature rise which promotes destruction of coloring agents.
{"title":"Dependence of light absorption on temperature changes in tattoo pigments","authors":"E. A. Leontiev, G. Struchko, V. A. Kozlov, A. L. Fedorov, T. Y. Leontyeva","doi":"10.37895/2071-8004-2023-27-1-34-38","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-34-38","url":null,"abstract":"Purpose: to study the quantitative intensity of optical density and light absorption of the electromagnetic radiation with tattoo pigment aqueous solution depending on its temperature.Material and methods. One hundred twenty-three of the most common commercial tattoo pigments were selected for the trial; 369 samples of aqueous solutions were made of them. Optical density of each pigment sample was determined at 14 and 77 °C. Then, each sample was exposed to optical radiation (IPL xenon lamp with pulsed light) at 14 and 77 °C.Results and discussion. Electromagnetic radiation with wavelengths 532 and 1064 nm increased tattoo pigment destruction from 78,27 to 84,37 % under temperature rise from 14 to 77 °C.Conclusion. Electromagnetic radiation of the optical range with wavelengths 532 and 1064 nm cannot destroy all tattoo pigments; however, optical density of solutions changes under temperature rise which promotes destruction of coloring agents.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76242851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-24DOI: 10.37895/2071-8004-2023-27-1-23-33
A. Vasiljev, N. Streltsova, I. Bessonov, G. Kolunin
Purpose: to assess possibility to extrapolate findings of skin microvascular bed examination in lower extremities with laser Doppler flowmetry in patients with obliterating atherosclerosis as a model of their myocardial microcirculation in coronary heart disease.Material and methods. Males with angiographically confirmed coronary heart disease (n = 70) and obliterating atherosclerosis in lower limbarteries (n = 74) were taken in the study. Microcirculation of the skin in the left forearm in the Zakharyin – Head zone in patients with coronaryheart disease and skin microcirculation in the foot of affected limb in patients with obliterating atherosclerosis of arteries of lower extremities were examined with laser Doppler flowmetry. The basal blood flow, amplitude-frequency spectrum of its oscillations, myogenic, neurogenic vascular tone and occlusion parameters were assessed as well. Comparison groups included 50 practically healthy males for the patients with coronary heart disease and 20 males – for the patients with obliterating atherosclerosis of arteries of lower extremities. Patients were examinedat the initial stage and in 2–3 weeks after endovascular restoration of blood flow in the myocardium and lower limbs.Results and discussion. At the initial research stage, the microcirculation picture in patients with coronary heart disease and obliterating ath-erosclerosis in lower extremities differed from that of healthy individuals by shifts covering all links of the microvascular bed and characterizedby constriction of the precapillary segment, a statistically significant decrease in median values of capillary blood flow by 17.5 and 43.1 %,microvascular blood flow reserve – by 11.2 and 31.0 %, as well as by the increase in arteriolovenular blood bypass – by 10.3 and 70.8 %,respectively. After the restoration of blood flow in lower extremities in patients with obliterating atherosclerosis, muscular pain disappeared,and the ankle-shoulder index got normalized. At the same time, one could observe a statistically significant increase in the capillary blood flow(+13.6 %), the increase of reserve potential in microvascular bed (+20.6 %) with the simultaneous decrease of vascular tone in the precapillarysegment (–15.1 %) and of the blood bypass index (–25.0 %). Better clinical picture after coronary angioplasty in patients with coronary heart disease was accompanied with a similar and unidirectional tendency to positive changes in the microvascular bed.Conclusion. As far as etiopathogenetic mechanisms and clinical manifestations of coronary heart disease and obliterating atherosclerosis in arteries of lower extremities have much in common and microcirculatory shifts in forearm and foot skin in these patients before and after angioplasty are unidirectional, all these allow to suggest that one can see similar changes in the myocardium microcirculatory system in patients with coronary heart disease. Thus, it opens possibilities to have a targeted medicamen
{"title":"The microvascular bed of the skin of lower limbs in patients with intermittent lameness and coronary heart disease as a possible model of their myocardial microcirculation","authors":"A. Vasiljev, N. Streltsova, I. Bessonov, G. Kolunin","doi":"10.37895/2071-8004-2023-27-1-23-33","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-1-23-33","url":null,"abstract":"Purpose: to assess possibility to extrapolate findings of skin microvascular bed examination in lower extremities with laser Doppler flowmetry in patients with obliterating atherosclerosis as a model of their myocardial microcirculation in coronary heart disease.Material and methods. Males with angiographically confirmed coronary heart disease (n = 70) and obliterating atherosclerosis in lower limbarteries (n = 74) were taken in the study. Microcirculation of the skin in the left forearm in the Zakharyin – Head zone in patients with coronaryheart disease and skin microcirculation in the foot of affected limb in patients with obliterating atherosclerosis of arteries of lower extremities were examined with laser Doppler flowmetry. The basal blood flow, amplitude-frequency spectrum of its oscillations, myogenic, neurogenic vascular tone and occlusion parameters were assessed as well. Comparison groups included 50 practically healthy males for the patients with coronary heart disease and 20 males – for the patients with obliterating atherosclerosis of arteries of lower extremities. Patients were examinedat the initial stage and in 2–3 weeks after endovascular restoration of blood flow in the myocardium and lower limbs.Results and discussion. At the initial research stage, the microcirculation picture in patients with coronary heart disease and obliterating ath-erosclerosis in lower extremities differed from that of healthy individuals by shifts covering all links of the microvascular bed and characterizedby constriction of the precapillary segment, a statistically significant decrease in median values of capillary blood flow by 17.5 and 43.1 %,microvascular blood flow reserve – by 11.2 and 31.0 %, as well as by the increase in arteriolovenular blood bypass – by 10.3 and 70.8 %,respectively. After the restoration of blood flow in lower extremities in patients with obliterating atherosclerosis, muscular pain disappeared,and the ankle-shoulder index got normalized. At the same time, one could observe a statistically significant increase in the capillary blood flow(+13.6 %), the increase of reserve potential in microvascular bed (+20.6 %) with the simultaneous decrease of vascular tone in the precapillarysegment (–15.1 %) and of the blood bypass index (–25.0 %). Better clinical picture after coronary angioplasty in patients with coronary heart disease was accompanied with a similar and unidirectional tendency to positive changes in the microvascular bed.Conclusion. As far as etiopathogenetic mechanisms and clinical manifestations of coronary heart disease and obliterating atherosclerosis in arteries of lower extremities have much in common and microcirculatory shifts in forearm and foot skin in these patients before and after angioplasty are unidirectional, all these allow to suggest that one can see similar changes in the myocardium microcirculatory system in patients with coronary heart disease. Thus, it opens possibilities to have a targeted medicamen","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75250822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-26DOI: 10.37895/2071-8004-2022-26-3-4-38-46
Purpose. To study specific approaches for selecting patients with rhonchopathy and obstructive sleep apnea syndrome for surgical treatment and to study laser surgical techniques applied on the soft palate so as to identify basic reasons of postoperative complications, soft palate function disorders and relapses of the disease with an even more aggressive course than before the surgery.Material and methods. In 2011–2020, 523 patients with rhonchopathy and obstructive sleep apnea syndrome, aged 23–78, were selected for surgical treatment. The authors discuss the obtained data after analyzing the effectiveness of used criteria for selecting patients for laser-assisted surgery on the soft palate, as well as after analyzing outcomes after laser sculptural uvulopalatoplasty performed in 309 patients. Reasons for insufficient effectiveness of surgery in some patients have been analyzed too.Results. After analyzing selection criteria, it has been found out that only 309 patients out of 523 (59.1 %) had no contraindications to laser sculptural uvulopalatoplasty, while 214 patients (40.9 %) had them. The discussed surgery was effective in 304 out of 309 operated patients (98.4 %) which has been confirmed with a complete and stable relief from night snoring and its complications for five or more years after the surgery. No effect was registered in 5 (1.6 %) patients because they absolutely ignored strict following the prescribed regimen, diet and other recommendations aimed to promote physiological healing of surgical wounds.Conclusion. The effectiveness of laser sculptural uvulopalatoplasty depends on a careful and adequate selection of patients for this surgery as well as on rational choice of laser light parameters; failures are due to inadequate selection of patients and their unwillingness to strictly follow recommendations in the postoperative period.
{"title":"Reasons for failure in surgical treatment of patients with rhonchopathy and obstructive sleep apnea syndrome","authors":"","doi":"10.37895/2071-8004-2022-26-3-4-38-46","DOIUrl":"https://doi.org/10.37895/2071-8004-2022-26-3-4-38-46","url":null,"abstract":"Purpose. To study specific approaches for selecting patients with rhonchopathy and obstructive sleep apnea syndrome for surgical treatment and to study laser surgical techniques applied on the soft palate so as to identify basic reasons of postoperative complications, soft palate function disorders and relapses of the disease with an even more aggressive course than before the surgery.Material and methods. In 2011–2020, 523 patients with rhonchopathy and obstructive sleep apnea syndrome, aged 23–78, were selected for surgical treatment. The authors discuss the obtained data after analyzing the effectiveness of used criteria for selecting patients for laser-assisted surgery on the soft palate, as well as after analyzing outcomes after laser sculptural uvulopalatoplasty performed in 309 patients. Reasons for insufficient effectiveness of surgery in some patients have been analyzed too.Results. After analyzing selection criteria, it has been found out that only 309 patients out of 523 (59.1 %) had no contraindications to laser sculptural uvulopalatoplasty, while 214 patients (40.9 %) had them. The discussed surgery was effective in 304 out of 309 operated patients (98.4 %) which has been confirmed with a complete and stable relief from night snoring and its complications for five or more years after the surgery. No effect was registered in 5 (1.6 %) patients because they absolutely ignored strict following the prescribed regimen, diet and other recommendations aimed to promote physiological healing of surgical wounds.Conclusion. The effectiveness of laser sculptural uvulopalatoplasty depends on a careful and adequate selection of patients for this surgery as well as on rational choice of laser light parameters; failures are due to inadequate selection of patients and their unwillingness to strictly follow recommendations in the postoperative period.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"20 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90767045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-26DOI: 10.37895/2071-8004-2022-26-3-4-75-78
L. V. Mikhaleva, Y. Alekseev
A clinical case of the successful use of light-oxygen therapy is presented irradiation in the absorption spectrum of endogenous oxygen with its transfer to a singlet state in a patient with vulvar leukoplakia and lichen sclerosus. As a source of laser radiation, we used the domestic Super Sab diode laser with a wavelength close to 1265 nm (OOO New Surgical Technologies, Moscow), radiation power – from 0.9 to 1.2 W, power density – from 0.8 to 1.06 W/cm2, exposure dose – 200–250 J/cm2. The procedures were carried out 2 times a week with an interval of 3–4 days.As a result of the treatment (8 procedures), complete clinical remission was achieved.
{"title":"Application of light-oxygen effect in gynecological practice (a case report)","authors":"L. V. Mikhaleva, Y. Alekseev","doi":"10.37895/2071-8004-2022-26-3-4-75-78","DOIUrl":"https://doi.org/10.37895/2071-8004-2022-26-3-4-75-78","url":null,"abstract":"A clinical case of the successful use of light-oxygen therapy is presented irradiation in the absorption spectrum of endogenous oxygen with its transfer to a singlet state in a patient with vulvar leukoplakia and lichen sclerosus. As a source of laser radiation, we used the domestic Super Sab diode laser with a wavelength close to 1265 nm (OOO New Surgical Technologies, Moscow), radiation power – from 0.9 to 1.2 W, power density – from 0.8 to 1.06 W/cm2, exposure dose – 200–250 J/cm2. The procedures were carried out 2 times a week with an interval of 3–4 days.As a result of the treatment (8 procedures), complete clinical remission was achieved.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83947946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-26DOI: 10.37895/2071-8004-2022-26-3-4-47-55
E. V. Ivanova, P. L. Volodin
Purpose: to construct a physical model based on the theory of activated complex (TAC) with indicators ΔH and ΔS mentioned in works of G.I. Zheltov and his colleagues so as to assess the impact of laser radiation micropulse modes at the chorioretinal complex (CRC), as well as to compare it with models based on the Arrhenius integral and with results of micropulse mode testing using autofluorescence method.Material and methods. Modeling of the degree of damage to CRC and adjacent structures was carried out using Eyring equation. Values of ΔH = 360 000 J/mol and ΔS = 890 J/mol·deg for complex of proteins and other RPE organic structures were determined by G.I. Zheltov and co-authors in vivo in a series of laser experiments on primates. For modeling, absorption coefficient of 460 cm–1 was used, for wavelength 577 nm – 10-micron-thick RPE layer and transmission 37 %. Micropulse mode testing (50 μs, 2.4 %, 10 ms, 100 mkm, 0.4–1.9 W) was performed using Navilas 577s navigation laser in patients aged 35–46 with appearance of types 2–3 by the Fitzpatrick scale; results of this testing were assessed using short-wave autofluorescence (488 nm) method.Results. A physical model based on TAC and Eyring integral was constructed. Results of modeling of the degree of RPE injury depending on power coincide with the results of testing of micropulse mode in patients according to autofluorescence method. The average RPE absorption coefficient equal to 440 cm–1 for patients aged 35–46 years and with appearance of type 2–3 by the Fitzpatrick scale was clarified.Conclusion. The computer modeling based on TAC using the Eyring equation with ΔH and ΔS for a complex of proteins and other RPE organic structures, which are described in works of G.I. Zheltov and his co-authors, has shown a high degree of compliance with the results of micro-pulse mode testing in real patients. Modeling does not require adjustment of any free parameters unlike approaches based on the Arrhenius equation; it also allows to find absorption coefficients for a small sample of patients and to assess the level of laser radiation damage to RPE and adjacent structures.
{"title":"Physical modelling to assess the effect of micropulse modes of laser radiation at the chorioretinal complex of the human eye based on the theory of activated complex","authors":"E. V. Ivanova, P. L. Volodin","doi":"10.37895/2071-8004-2022-26-3-4-47-55","DOIUrl":"https://doi.org/10.37895/2071-8004-2022-26-3-4-47-55","url":null,"abstract":"Purpose: to construct a physical model based on the theory of activated complex (TAC) with indicators ΔH and ΔS mentioned in works of G.I. Zheltov and his colleagues so as to assess the impact of laser radiation micropulse modes at the chorioretinal complex (CRC), as well as to compare it with models based on the Arrhenius integral and with results of micropulse mode testing using autofluorescence method.Material and methods. Modeling of the degree of damage to CRC and adjacent structures was carried out using Eyring equation. Values of ΔH = 360 000 J/mol and ΔS = 890 J/mol·deg for complex of proteins and other RPE organic structures were determined by G.I. Zheltov and co-authors in vivo in a series of laser experiments on primates. For modeling, absorption coefficient of 460 cm–1 was used, for wavelength 577 nm – 10-micron-thick RPE layer and transmission 37 %. Micropulse mode testing (50 μs, 2.4 %, 10 ms, 100 mkm, 0.4–1.9 W) was performed using Navilas 577s navigation laser in patients aged 35–46 with appearance of types 2–3 by the Fitzpatrick scale; results of this testing were assessed using short-wave autofluorescence (488 nm) method.Results. A physical model based on TAC and Eyring integral was constructed. Results of modeling of the degree of RPE injury depending on power coincide with the results of testing of micropulse mode in patients according to autofluorescence method. The average RPE absorption coefficient equal to 440 cm–1 for patients aged 35–46 years and with appearance of type 2–3 by the Fitzpatrick scale was clarified.Conclusion. The computer modeling based on TAC using the Eyring equation with ΔH and ΔS for a complex of proteins and other RPE organic structures, which are described in works of G.I. Zheltov and his co-authors, has shown a high degree of compliance with the results of micro-pulse mode testing in real patients. Modeling does not require adjustment of any free parameters unlike approaches based on the Arrhenius equation; it also allows to find absorption coefficients for a small sample of patients and to assess the level of laser radiation damage to RPE and adjacent structures.","PeriodicalId":10008,"journal":{"name":"Chinese Journal of Laser Medicine & Surgery","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86775460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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