Child Psychiatry & Human Development最新文献

Lifetime social adversity predicts elevated depressive symptoms in adolescence. However, most adversity-exposed youth do not develop depression, highlighting the importance of examining risk and protective factors. The present study leveraged a multi-method approach, incorporating self-report, interview, and independent coding to examine whether appraisals of recent stressors moderate the effect of social adversity on depressive symptoms in 81 adolescent girls (M_age = 16.30 years, SD = .85). We utilized semi-structured interviews of lifetime adversity and recent stressors and semi-structured interviews and self-reports of depressive symptoms. Stress appraisals were calculated by regressing youths' subjective estimations of event stressfulness and dependence on estimations of independent coders. Lifetime social adversity predicted elevated depressive symptoms more strongly in girls who appraised interpersonal events as more stressful and dependent on their actions, providing insight into individual differences in depressive symptoms in adversity-exposed adolescents.

Attention deficit hyperactivity disorder (ADHD) is a frequently diagnosed neurodevelopmental disorder in children and adolescents. The objective of this review was to synthesize empirical studies that investigated the effects of physical activity (PA) on motor proficiency in this population. A systematic review and meta-analysis were conducted following the cochrane guidelines for systematic reviews. In May 2022, a systematic search of eight electronic databases retrieved 476 results, which were screened independently by two reviewers. Based on the inclusion and exclusion criteria, 12 studies were selected for systematic review, and 10 were included in the meta-analysis. A beneficial effect of PA on overall motor proficiency (SMD = 1.12; 95% CI [0.63 to 1.61]; p < 0.05) was observed. Similar positive effects were found for motor proficiency composites, including object control, fine manual control, and body coordination. These results indicate that PA improves the motor proficiency of children and adolescents with ADHD.

Transgender youth experience high rates of suicidal ideation and suicide attempts. This systematic review sought to examine interventions for suicide prevention in transgender children and adolescents. Literature related to suicide in the transgender population was systematically collected in accordance with PRISMA criteria. Searches identified studies with at least one suicide prevention method for participants ages 24 years or younger with gender identity and sex clearly defined. Primary outcomes include suicide-related thoughts and behaviors. A total of 1558 citations were identified with 17 articles meeting inclusion criteria. Interventions with potential effectiveness included a gender-affirming crisis hotline, medical care via interdisciplinary gender clinics, online media-based outreach, safety and connectedness in schools, and family system-based interventions. In the included studies, the overall quality of evidence was low and the risk of bias high. Further high-quality studies are needed.

This study examined a two-mediator model with both empathy and anger as mediators in the association between children's normative beliefs about aggression and forms (relational and physical) and functions (reactive and proactive) of aggressive behavior. Ninety-eight children (54% males, M_age=46.21months, SD = 8.84months) reported their approval of relationally and physically aggressive behaviors depicted in iconic (animation) and enactive (toy figurines) hypothetical scenarios. Children's aggression, empathy and anger were measured using teacher reports. No main effects of normative beliefs about aggression on the corresponding aggressive behavior were found. Normative beliefs about aggression were negatively associated with empathy and empathy was significantly associated with relational aggression, suggesting that developing social emotional processes mediate the relation between social cognitions and aggression. Anger was associated with aggression, but not normative beliefs about aggression. The findings provide support for the distinction between subtypes of aggressive behavior in young children and the developing social-cognitive and affective processes that influence these behaviors.

Health-threatening underweight and poor growth is a frequent consequence of Avoidant restrictive food intake disorder (ARFID) and should be a priority for treatment in children and adolescents (young people, YP). Coexisting autism is more prevalent in YP with ARFID than in YP with other eating disorders. Treatment studies are still sparse for ARFID, and it is not known whether treatment response is lower in those with coexisting autism, as it is documented in other eating disorders. In this study we examined if family-based treatment for ARFID (FBT-ARFID) was associated with weight gain in underweight young people (YP) with ARFID and if coexisting autism affected weight gain. A clinical naturalistic prospective case series of 33 YP aged 6.3-18 years with ARFID presentations and underweight were offered a manualized FBT-ARFID with weight monitoring. We examined changes in body weight between start and end of treatment in those with and without diagnosed coexisting autism. The majority of participants (N = 26, 79%) had a weight gain between 1 and 15 kg, whereas 7 YP (21%) had a stable body weight between start and end of treatment (differences between - 0.6 kg and + 0.9 kg). At the group level, weight gain was statistically significant between start and end (Median = 3.9 kg (4.0, -0.6 -15.1) z = 4.491, p <.001). There was no significant difference in weight gain between participants with (N = 14, 42%) and without (N = 19, 58%) coexisting autism. Participants had a significant weight gain at the group level, suggesting that FBT-ARFID is associated with weight gain in the majority of underweight ARFID patients, both with and without coexisting autism. However, a subgroup may need additional interventions in order to secure weight rehabilitation.

Little data exist to guide suicide assessment protocols in preadolescent youth. Using the Adolescent Brain Cognitive Development (ABCD) data (N = 10,010) at baseline (ages 9-10) and 24-month follow-up (ages 11-12), this report investigates informant agreement/disagreement in caregiver- and youth- reports of suicidal ideation and their associations with youth sex assigned at birth and symptomatology across preadolescence. Using the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) at both timepoints, four informant discrepancy groups were created from caregiver- and youth- reported suicidal ideation: (1) Concordant No; (2) Concordant Yes; (3) Discordant Caregiver Yes, Youth No; (4) Discordant Caregiver No, Youth Yes. Internalizing and externalizing symptoms were measured at the 24-month follow-up using the caregiver-report Child Behavior Checklist and the youth-report ABCD Brief Problem Monitor. Results indicated low-to-fair caregiver-youth agreement for youth suicidal ideation across preadolescence. Suicidal ideation reported by youth, but not caregivers, demonstrated a shift in prevalence at the follow-up, with females surpassing males in self-reported endorsements. Finally, informant groups at both time points were associated with caregiver- and youth-reported youth symptomatology at the 24-month follow-up, and associations varied by reporter. Findings demonstrate the importance of leveraging both caregiver and youth reports to assess preadolescent suicidal ideation and highlight the clinical utility of informant discrepancies in assessing suicide risk. The accurate assessment of suicidal ideation in preadolescents is essential to curb the increasing rates of preadolescent suicide and identify at-risk youth for interventions prior to even larger uptick of suicide in adolescence.

Among a large sample of youth (9-10 years old at baseline) from the Adolescent Brain Cognitive Development (ABCD) Study® (n = 11,661) we modeled trajectories of psychopathology over three years and associated risk and protective factors. Growth mixture modeling characterized latent classes with distinct psychopathology trajectories. Results indicated four different internalizing trajectories: a high-decreasing class, a moderate-decreasing class, a moderate-increasing class, and a low-stable class. There were also four externalizing trajectories: a moderate-decreasing class, a high-decreasing class, a moderate-increasing class, and a low-decreasing class. We used parallel process growth analysis to examine the co-development of internalizing and externalizing symptoms and characterized five trajectory classes with distinct patterns of co-development. These classes were differentially associated with negative life events, neighborhood safety, and parental acceptance. Together, the findings characterize general developmental patterns of psychopathology, quantify the proportion of youth that follow each pattern, and identify key predictors that discriminate these patterns.

The diagnosis of bipolar disorder (BD) in young children has been a topic of debate, in part owing to varied interpretation of manic-like symptoms. We examined how expert academic clinicians participating in the pediatric bipolar biobank varied in their interpretation and application of Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria and diagnoses. Study co-investigators reviewed 12 standardized narratives and for each marked a visual analog scale with their confidence in the presence of manic episodes and criteria. We analyzed raters' confidence and inter-rater agreement using interclass correlation (ICC). Symptoms with good ICC ranging from 0.60 to 0.74 included inflated self-esteem/grandiosity and decreased need for sleep. Diagnoses and episodes with poor ICCs (< 0.4) included Hypomania and Bipolar Not Elsewhere Classified/Not Otherwise Specified. Despite efforts made to refine BD criteria with DSM-5, there was substantive variation in diagnostic interpretation among investigators working with children presenting with manic-like symptoms.

Positive Childhood Experiences (PCEs) may mitigate the negative outcomes resulting from Adverse Childhood Experiences (ACEs). To date, most PCE research has used cross-sectional or retrospective designs. PubMed, EMBASE, Cochrane, PsychINFO, CINAHL, and Scopus were searched in May 2024 for longitudinal studies that examined the impact of cumulative PCEs. Eight publications from five longitudinal studies with a total of 16,451 participants were included. Three studies focused only on adolescent outcomes. PCEs were associated with reduced rates of depression, substance use, delinquent behavior, risky sexual behavior, persistent insomnia, and lower inflammatory markers. Cumulative PCEs in childhood may moderate the impact of ACEs, potentially playing an important role in reducing the risk for mental disorders and other adverse outcomes later in life.PROSPERO (ID: CRD42022384775).