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Myricetin attenuates the inflammatory bowel disease in prediabetic mice via inflammation inhibition and gut microbiota modulation 杨梅素通过抑制炎症和调节肠道微生物群减轻糖尿病前期小鼠的炎症性肠病
Pub Date : 2024-04-19 DOI: 10.1002/fsh3.12041
Li Yang, Yongchao Gao, Hui Wang, Weizhi Zhong, Jupeng Gong, Mohamed A. Farag, Yonghua Zhao, Jianbo Xiao

Myricetin shows great anti-inflammatory effect on colitis and supplementation with myricetin could improve gut microbiota dysbiosis. It is reported that the abnormal blood glucose condition of prediabetes could aggravate the progression of inflammation. However, there is no report on whether myricetin has the protective effect on inflammation comorbid prediabetes. This study aimed to explore the effect and potential mechanism of myricetin on dextran sulfate sodium (DSS)-induced colitis in prediabetic mice. Several indexes related to colitis were evaluated on DSS-induced prediabetic mice. Myricetin intervention improved body weight loss, disease activity index score in DSS-induced colitis in prediabetic mice. Myricetin alleviated inflammation by inhibiting proinflammatory cytokines and myeloperoxidase production in DSS-induced colitis in prediabetic mice. Furthermore, myricetin showed recovery of intestinal barrier integrity by increasing the expression of tight junction proteins (ZO-1, Occludin and Claudin-1). At the gut microbiota level, myricetin showed protective effects via modulating gut dysbiosis associated with DSS-induced colitis in prediabetic mice. In addition, myricetin could significantly increase the short chain fatty acids produced by gut microbiota. Myricetin may be serving as a novel therapeutic agent which could be used in the treatment of DSS-induced colitis in prediabetic patients in the future with its added value as well reported antidiabetic agent.

杨梅素对结肠炎有很好的抗炎作用,补充杨梅素可以改善肠道微生物群失调。据报道,糖尿病前期的血糖异常会加剧炎症的发展。然而,目前还没有关于麦角素对糖尿病前期合并的炎症是否有保护作用的报道。本研究旨在探讨麦角素对右旋糖酐硫酸钠(DSS)诱导的糖尿病前期小鼠结肠炎的影响及其潜在机制。该研究对右旋糖酐硫酸钠(DSS)诱导的糖尿病前期小鼠结肠炎的几项相关指标进行了评估。在DSS诱导的糖尿病前期小鼠结肠炎中,三尖杉酯素干预可改善体重减轻和疾病活动指数评分。在 DSS 诱导的糖尿病前期小鼠结肠炎中,杨梅素通过抑制促炎细胞因子和髓过氧化物酶的产生来缓解炎症。此外,米力西汀还能增加紧密连接蛋白(ZO-1、Occludin 和 Claudin-1)的表达,从而恢复肠道屏障的完整性。在肠道微生物群水平上,通过调节与 DSS 诱导的糖尿病前期小鼠结肠炎相关的肠道菌群失调,三叶草素显示出保护作用。此外,杨梅素还能显著增加肠道微生物群产生的短链脂肪酸。麦角黄素可作为一种新型治疗药物,未来可用于治疗糖尿病前期患者的 DSS 诱导的结肠炎,其附加价值是抗糖尿病药物。
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引用次数: 0
A descriptive review on exploiting the therapeutic significance of essential oils as a potential nutraceutical and food preservative 关于利用精油作为潜在营养保健品和食品防腐剂的治疗意义的描述性综述
Pub Date : 2024-04-11 DOI: 10.1002/fsh3.12042
Bisma Jan, Bharti Choudhary, Zoya Malik, Mohammad Imran Dar

For centuries, essential oils (EOs) have held a significant place in traditional medicinal practices worldwide and are commonly known for their aroma and taste. Among the 3000 recognized types, only 300 have commercial use in the food and pharmaceutical sectors. These potent natural extracts, derived from aromatic plants and herbs, have garnered attention not only in ancient healing traditions but also within modern health-care systems. Their rich history is marked by a diverse array of therapeutic properties that have made them indispensable tools for promoting health and well-being. Additionally, the utilization of EOs as food preservatives is an innovative and natural approach in extending the shelf life of various food products. In addition, EOs are beneficial in the treatment of cancer and other diseases. Because of their outstanding biological activities and health benefits, research on EOs has exploded in recent years. In present work, an intensive review was done on published data on therapeutic potential of some major EOs and their utilization as a preservative in food industries. Meanwhile, an investigation of the methods specifically used for the separation of EOs and regulatory considerations are also reported. The article concludes with comments on future trends.

几个世纪以来,精油(EOs)在世界各地的传统医药实践中一直占据着重要地位,并因其香气和味道而广为人知。在公认的 3000 种精油中,只有 300 种在食品和医药领域有商业用途。这些从芳香植物和草药中提取的强效天然提取物不仅在古老的治疗传统中备受关注,在现代医疗保健系统中也是如此。它们丰富的历史以其多种多样的治疗特性为标志,使其成为促进健康和福祉不可或缺的工具。此外,将环氧乙烷用作食品防腐剂也是延长各种食品保质期的一种创新而自然的方法。此外,环氧乙烷还有助于治疗癌症和其他疾病。由于环氧乙烷具有突出的生物活性和保健作用,近年来对环氧乙烷的研究呈爆炸式增长。本研究对一些主要环氧乙烷的治疗潜力及其在食品工业中用作防腐剂的已发表数据进行了深入综述。同时,还报告了专门用于分离环氧乙烷的方法和监管方面的考虑。文章最后对未来趋势进行了评论。
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引用次数: 0
Simultaneous detection of melamine and cyanuric acid using powder X-ray diffraction 利用粉末 X 射线衍射同时检测三聚氰胺和三聚氰酸
Pub Date : 2024-03-18 DOI: 10.1002/fsh3.12039
R. Paranthaman, J. A. Moses, R. Vidyalakshmi

A novel, non-destructive, powder X-ray diffraction (P-XRD) approach was developed and validated for the simultaneous detection of melamine (ME) and cyanuric acid (CA). Sample holders, and a range of P-XRD X-ray tube parameters (voltage: 25–45 kV; current: 25–45 mA), and scanning conditions (scan step size: 0.006–0.10°; step time: 50–150 s) were experimented at 2θ conditions. Based on the obtained diffraction patterns, the following conditions were optimized: sample holder: reflection-transmission spinner, tube voltage: 45 kV, tube current: 45 mA, scan step size: 0.006°, and scan step time: 150 s. The crystalline properties were assessed and phase quantification of both ME and CA was performed using Rietveld refinement, aligning to the International Center for Diffraction Data (ICDD) PDF4+ 2023 library. The approach was validated considering repeatability, precision, and linearity, and recovery and stability studies also support the findings. The limit of detection (LOD) was found to be 0.2 to 1 wt. % per phase of powder sample. Then, spiked and real food powder samples were screened for ME and CA. To date, there is no nondestructive technique available to simultaneously detect ME and CA in a single run. The developed P-XRD approach can find vast applications in quality testing facilities.

为同时检测三聚氰胺(ME)和三聚氰酸(CA),开发并验证了一种新型、无损的粉末 X 射线衍射(P-XRD)方法。在 2θ 条件下,对样品架、一系列 P-XRD X 射线管参数(电压:25-45 kV;电流:25-45 mA)和扫描条件(扫描步长:0.006-0.10°;步长时间:50-150 s)进行了实验。根据所获得的衍射图样,对以下条件进行了优化:样品架:反射-透射旋转器,试管电压:45 kV,试管电流:45 mA,扫描步长:0.006°,扫描步长:150 s。采用国际衍射数据中心(ICDD)PDF4+ 2023 库,利用里特维尔德细化法评估了晶体特性,并对 ME 和 CA 进行了相定量。该方法在重复性、精确性和线性方面都得到了验证,回收率和稳定性研究也支持这些结论。发现每相粉末样品的检测限(LOD)为 0.2 至 1 wt.%。然后,对添加了 ME 和 CA 的粉末样品和真正的粉末样品进行了筛查。迄今为止,还没有一种无损技术能在一次运行中同时检测出 ME 和 CA。所开发的 P-XRD 方法可广泛应用于质量检测机构。
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引用次数: 0
Guidelines for Raman spectroscopy and imaging techniques in food safety analysis 食品安全分析中的拉曼光谱和成像技术指南
Pub Date : 2024-03-18 DOI: 10.1002/fsh3.12040
Ning Li, Nisar Hussain, Zhongxiang Ding, Cheng Qu, Yuzhu Li, Leiming Chu, Honglin Liu

Ensuring the highest standards of food quality and safety is crucial for maintaining human health. This requires the creation of sophisticated and highly sensitive techniques for detecting and identifying food pollutants. Raman spectroscopy, known for its rapidity, simplicity, sensitivity, and noninvasive characteristics, has become a prominent method in the field of food safety and quality analysis. This review discusses in detail the fundamental principles, instruments, methodology, and data processing techniques of Raman spectroscopy. It specifically emphasizes the practical applications of Raman spectroscopy in assessing foodborne pathogens, toxic gases in spoiled foods, and monitoring the translocation of pesticide in plants. Finally, we discussed the development trend and challenges of Raman spectroscopy in the field of food safety analysis, aiming to provide an accessible and practical guide. This review article equips readers with essential insights into conducting and understanding Raman spectroscopy experiments, thereby contributing to development in the field of food safety analysis.

确保最高标准的食品质量和安全对于维护人类健康至关重要。这就需要开发先进的高灵敏度技术来检测和识别食品污染物。拉曼光谱以其快速、简便、灵敏和无创的特点而著称,已成为食品安全和质量分析领域的一种重要方法。本综述详细讨论了拉曼光谱的基本原理、仪器、方法和数据处理技术。它特别强调了拉曼光谱在评估食源性病原体、变质食品中的有毒气体以及监测植物中农药转移方面的实际应用。最后,我们讨论了拉曼光谱在食品安全分析领域的发展趋势和挑战,旨在提供一本通俗易懂的实用指南。这篇综述文章为读者提供了进行和理解拉曼光谱实验的基本见解,从而为食品安全分析领域的发展做出了贡献。
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引用次数: 0
Chaihu Guizhi decoction ameliorates depression symptoms in chronic restraint stress-induced depressive rats by regulating gut microbiota and short-chain fatty acids 柴胡桂枝煎剂通过调节肠道微生物群和短链脂肪酸改善慢性束缚应激诱导的抑郁大鼠的抑郁症状
Pub Date : 2024-03-17 DOI: 10.1002/fsh3.12038
Dong Peng, Yuying Cheng, Yanlan Chen, Xin Cai, Hanxiao Bao, Xiangmin Pan, Wanyue Ding, Jianping Chen, Pan Li

Chaihu Guizhi decoction (CJY) is a classic formula with antidepressant effects; however, it remains unclear whether the antidepressant mechanism of CJY involves modulation of the gut microbiota and which specific bacterial genera are regulated. The present study investigated the effects of CJY on the gut microbiota in chronic restraint stress (CRS)-induced depressive rats. The results showed that CJY treatment attenuated depressive-like behavior, repaired hippocampal neuronal damage, and increased neurotransmitter levels in CRS-induced depressive rats. CJY reshaped the gut microbiota spectrum by increasing the level of the key bacterial genera that alleviate depression, such as Lactobacillus, while decreasing the level of the key bacterial genera that exacerbate depression, such as Bacteroides, Parabacteroides, and Lachnoclostridium. In addition, CJY restored the gut flora dysbiosis-derived changes in the production of short-chain fatty acids, such as acetic acid, propionic acid, and valeric acid. This study lays the foundation for identifying therapeutic targets for CJY and elucidating its underlying mechanisms from the perspective of the microbiota.

柴胡桂枝煎(CJY)是一种具有抗抑郁作用的经典方剂;然而,柴胡桂枝煎的抗抑郁机制是否涉及对肠道微生物群的调节,以及哪些特定细菌属受到了调节,目前仍不清楚。本研究调查了 CJY 对慢性束缚应激(CRS)诱导的抑郁大鼠肠道微生物群的影响。结果显示,CJY 治疗可减轻 CRS 诱导的抑郁大鼠的抑郁样行为,修复海马神经元损伤,并提高神经递质水平。CJY 重塑了肠道微生物群谱,提高了乳酸杆菌等缓解抑郁的关键细菌属的水平,同时降低了乳酸菌属、副乳酸菌属和拉赫诺梭菌属等加剧抑郁的关键细菌属的水平。此外,CJY 还能恢复肠道菌群失调引起的短链脂肪酸(如乙酸、丙酸和戊酸)生成的变化。这项研究为确定 CJY 的治疗靶点以及从微生物群的角度阐明其潜在机制奠定了基础。
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引用次数: 0
Genetic determinants of thermal resistance in foodborne bacterial pathogens 食源性细菌病原体耐热性的遗传决定因素
Pub Date : 2024-03-08 DOI: 10.1002/fsh3.12037
Aswathi Soni, Gale Brightwell

Thermal food processing stands as the conventional and prevalent intervention utilized by food industries to uphold food safety standards. Some bacteria are known to withstand thermal treatments up to definite extents. This ability primarily stems from genetically determined traits that can be influenced by environmental conditions. This review focuses on the genetic determinants of thermal resistance in foodborne pathogens including the locus of heat resistance (LHR). Genes contributing to the expression of proteins that might indirectly contribute to thermal resistance have also been covered. The emergence of thermal tolerance in these pathogens raises significant food safety concerns, given global worries about bacterial resistance. The review consolidates existing research on genetic components and loci of heat resistance and highlights potential areas of gaps that warrant further research. Furthermore, acquired cross-protection leading to resistance across multiple interventions has also been highlighted as an emerging concern. Acquiring insights into the environmental conditions that promote the selection of the LHR will empower the adoption of more efficient strategies to obstruct the pathways by which these pathogens persist within processing chains.

食品热处理是食品工业用来维护食品安全标准的传统和普遍的干预措施。众所周知,有些细菌能在一定程度上耐受热处理。这种能力主要源于基因决定的性状,而这些性状会受到环境条件的影响。本综述重点探讨食源性病原体耐热性的基因决定因素,包括耐热基因座(LHR)。此外,还介绍了有助于表达可能间接产生耐热性的蛋白质的基因。鉴于全球对细菌耐药性的担忧,这些病原体耐热性的出现引发了重大的食品安全问题。本综述整合了有关耐热性基因成分和基因位点的现有研究,并强调了需要进一步研究的潜在空白领域。此外,后天交叉保护导致多种干预措施产生抗药性也是一个新出现的问题。深入了解促进选择 LHR 的环境条件,将有助于采取更有效的策略,阻断这些病原体在加工链中持续存在的途径。
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引用次数: 0
Interactions of proteins and phenolics: A case for pulse proteins and onion flavonoids 蛋白质与酚类物质的相互作用:脉冲蛋白质和洋葱类黄酮的案例
Pub Date : 2024-02-16 DOI: 10.1002/fsh3.12035
Deniz Günal-Köroğlu, Esra Capanoglu

Researchers and the food industry are interested in the development of new plant-based products rich in proteins, considering the environmental, religious, and health concerns of consumers against animal-based proteins. Essentially, plant-based proteins have affordable prices, advantageous qualities, are renewable and biodegradable, and cause comparatively milder allergic reactions (X. Zhang, Wang, et al., 2022). Size, shape, amino acid composition and sequence, net charge and distribution, hydrophobicity/hydrophilicity ratio, secondary, tertiary, and quaternary structures, molecular flexibility/rigidity, and the ability to interact/react with other components are among the physical and chemical characteristics that control protein functionality (Damodaran, 2008). Functional properties of pulse proteins are significant topics for the food industry as alternative protein sources started to be used in different products such as gluten-free products or vegan mayonnaise (Du et al., 2014). Proteins in foods differ in (1) protein amount, (2) amino acid composition, (3) digestibility, (4) rate of protein digestion, and (5) capacity to transfer amino acids for protein synthesis. Animal proteins are efficiently utilized for protein synthesis, contain all of the essential amino acids, and are often well digested. Therefore, animal proteins are regarded as “high quality” (Gilbert et al., 2011). On the other hand, plant-based proteins cannot be widely used in foods as of animal proteins. The use of plant proteins including soy and other legume and oilseed proteins, is limited in conventional foods. These proteins do not function as effectively as animal proteins in most food products, even though they are similar combinations of proteins. There is a lack of knowledge on the precise molecular characteristics of proteins that give rise to several beneficial functions in foods (Damodaran, 2008), and still many research studies are being conducted to overcome these challenges in plant-based proteins and improve their nutritional and techno-functional qualities.

Proteins and phenolic compounds coexist naturally in many foods or food matrices; however, phenolics do not interact directly with proteins since they are found in vacuoles in plants (Rohn, 2014). For phenolics to interact with proteins, plant tissue must be broken down by the effects of food processing and gastrointestinal digestion. Thus, proteins and phenolic compounds in the same environment interact in different ways (Le Bourvellec & Renard, 2012). Protein–phenolic interaction is classified as reversible or irreversible. The protein–phenolic interactions are affected by covalent and non-covalent (hydrogen bonding, hydrophobic interactions, and Van der Waals forces) interactions (Ozdal et al., 2013).

Onion and onion skin contain high levels of antioxidant flavonoids. The most domi

有研究指出,在槲皮素的作用下,脉冲蛋白质的乳化性能会得到改善(Fu 等人,2023 年;L. Han, Lu 等人,2021 年;Y. Zhang, Wang 等人,2022 年)。部分展开和更柔韧的蛋白质可提高乳化和发泡能力,因为它们很容易扩散到空气-水或油-水界面,降低气泡或油滴的表面张力(Y. Zhang, Wang, et al.)在达到一定浓度时,酚类化合物能够改善蛋白质衍生乳液的特性。由于环境中存在的酚类化合物越多,相互作用就越饱和(酚类化合物过量),乳液特性就会受到不利影响。文献中研究的乳液大多是水包油型乳液,含油量分别为 5%(J. Han、Du 等,2021 年)、20%(Fu 等,2023 年)和 25%(Y. Zhang、Wang 等,2022 年)。然而,Günal-Köroğlu、Turan 和 Capanoglu(2022 年)发现黄洋葱皮酚类提取物对乳液(50% 油)和发泡特性有明显影响。乳液中酚类化合物含量越高,油的比例越高,其影响可能就越明显。研究发现,酚类化合物对扁豆蛋白的乳化/发泡特性有很大影响,具体取决于浓度。在蛋白质浓度较低或酚类浓度较高的情况下,由于界面上游离酚类的增加(非相互作用)、蛋白质表面疏水性的降低以及蛋白质的解折,发泡或乳化性能受到不利影响(Günal-Köroğlu, Turan, &amp; Capanoglu, 2022)。在超声或高温应用下,观察到槲皮素的溶解度增加(Chen et al、由于在溶液中形成了胶体复合物,槲皮素的溶解度得以提高(Chen 等人,2018;Liao 等人,2022;Lin 等人,2023)。蛋白质构象的改变为其表面提供了更多的疏水基团,从而增加了槲皮素的可用结合位点数量(Liao 等人,2022 年)。脉冲蛋白质溶液中的游离槲皮素和结合槲皮素通常描述了槲皮素的总量。结合型槲皮素以蛋白质-槲皮素复合物的形式溶解,但游离型槲皮素可立即溶于水(Liao 等人,2022 年)。此外,Chen 等人(2018 年)和 Liao 等人(2022 年)暗示,所有蛋白质(大豆、乳清和酪蛋白酸钠)都可以用来增加槲皮素的溶解度,但每种蛋白质的效率各不相同。由于槲皮素的水溶性较弱,且在生理条件下会发生化学变化,因此主要在水基食品(如饮料)中,槲皮素的生物可及性相对较低(陈等人,2018;廖等人,2022)。水包油乳剂尤其适合用作辅料食品(Chen 等,2018 年)。槲皮素的水溶性较差,降低了其在肠细胞中的转运和随后的吸收,这是其生物可及性有限的主要原因。在消化过程中,槲皮素必须在肠道阶段被分化成胆盐混合胶束,才能被吸收。胃的极度酸性会导致槲皮素骨架结构的分解。槲皮素在胃部阶段应被纳米复合物屏蔽,这样才能在肠道中释放出来(L. Han, Lu, et al.,2021)。槲皮素从食物基质中释放到水性胶束部分并容易被肠道粘膜吸收的部分被称为槲皮素生物可接受性(Lin 等人,2023 年)。此外,蛋白质分解产生的肽可能会相互作用,促进胶束化,增加槲皮素的溶解度(Chen 等,2018;Günal-Köroğlu、Yılmaz 等,2022;L. Han、Lu 等,2021;Liao 等,2022;Lin 等,2023)。乳剂中的槲皮素具有更高的溶解度和生物可及性。由于蛋白质相互作用增加了槲皮素在混合胶束疏水内部的溶解度,蛋白质分解也可能导致胶束化,从而促进了槲皮素的溶解(Chen 等,2018 年)。Günal-Köroğlu、Turan 和 Capanoglu(2022 年)报道,黄洋葱皮酚提取物中最主要的酚类化合物是槲皮素 7,4-二葡萄糖苷和槲皮素。然而,在所有溶液体系(酚溶液、扁豆蛋白-酚溶液和扁豆蛋白-酚乳液)中,黄洋葱皮酚提取物中的槲皮素在进入肠道阶段后都无法检测到,而且槲皮素 7,4-二葡萄糖苷的含量显著下降。
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引用次数: 0
Wine is more than just a beverage: Chemical diversity, health benefits, and immunomodulating potential of wine polyphenols 葡萄酒不仅仅是一种饮料:葡萄酒多酚的化学多样性、健康益处和免疫调节潜力
Pub Date : 2024-02-15 DOI: 10.1002/fsh3.12036
Danka Mitrović, Ivana Sredović Ignjatović, Maja Kozarski, Jelena Popović- Đorđević

Wine, the fermented juice of the grape (Vitis vinifera), is a complex beverage composed primarily of water and ethanol. On the other hand, phenolic compounds are less abundant components that participate in taste and color formation. In addition to their major role in the sensory profile of wine, phenolic compounds (also referred as polyphenols) function through various mechanisms, exerting positive influence on health. According to recent research, consuming just one glass of red wine positively contributes to health protection, and it is connected to the maintenance of the redox endothelial balance, potential for reducing diabetes occurrence, preventing atherosclerosis, and reducing the risk of cardiovascular diseases. What is more, a lower incidence of certain types of cancers has also been observed. The health promoting benefits of wine are explained by its wide spectrum of structurally diverse phenolic compounds whose content may depend on numerous factors. The most abundant compounds are anthocyanins with up to 400 mg/L, followed by phenolic acids, flavanols, flavonols, hydrolyzable tannins, flavanones, and stilbenes (up to 200, 120, 60, 50, 25, and 5 mg/L, respectively). This review paper outlines the structural variety, health advantages, and immunomodulatory capacity of wine polyphenols, drawing upon the latest and most pertinent scientific literature available in this domain.

葡萄酒是葡萄(葡萄属)的发酵汁,是一种主要由水和乙醇组成的复杂饮料。另一方面,酚类化合物是参与口感和颜色形成的含量较少的成分。酚类化合物(又称多酚)除了在葡萄酒的感官特征中发挥重要作用外,还通过各种机制发挥作用,对健康产生积极影响。根据最近的研究,只需饮用一杯红葡萄酒就能对健康起到积极的保护作用,它与维持氧化还原内皮平衡、减少糖尿病发生、预防动脉粥样硬化和降低心血管疾病风险有关。此外,还观察到某些类型癌症的发病率较低。葡萄酒对健康的促进作用是由其广泛的结构多样的酚类化合物造成的,其含量可能取决于多种因素。含量最高的化合物是花青素,高达 400 毫克/升,其次是酚酸、黄烷醇、黄酮醇、可水解单宁、黄烷酮和二苯乙烯类化合物(分别高达 200、120、60、50、25 和 5 毫克/升)。这篇综述文章概述了葡萄酒多酚的结构多样性、健康优势和免疫调节能力,并参考了该领域最新和最相关的科学文献。
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引用次数: 0
Prevalence and characterization of Staphylococcus aureus from different processing points in beef processing plants in Shandong, China 中国山东牛肉加工厂不同加工点金黄色葡萄球菌的感染率和特征描述
Pub Date : 2024-01-22 DOI: 10.1002/fsh3.12033
Tianning Zhang, Yunge Liu, Xiaoyin Yang, Benzhi Gong, Rongrong Liang, Yanwei Mao, Yimin Zhang, Pengcheng Dong, Lixian Zhu

Staphylococcus aureus (S. aureus) is a common zoonotic foodborne pathogen that poses a serious threat to the microbial control of meat processing, especially the multidrug resistant (MDR) strain. This study aimed to investigate the prevalence, antimicrobial susceptibility, virulence genes, biofilm formation ability (BFA), and molecular types of S. aureus isolated from two beef-processing plants in China. The results revealed that the prevalence of S. aureus was 17.1% (60/350), including one methicillin-resistant strain. The chilled carcass showed the highest detection rate among the seven sampling points. The isolates exhibited high resistance to penicillin (88.3%) and lincomycin (80.0%), and 75.0% of the isolates showed multidrug resistance (MDR). All isolates carried hla and clfa and critical toxin genes (seb, pvl, and tst) were also detected. Additionally, 96.7% of isolates exhibited strong and moderate BFA. The isolates were typed by Multilocus Sequence Typing (MLST) and Staphylococcus Protein A (spa) typing methods, resulting in nine different types for each method. The predominant type was ST7-t091, accounting for 68.3% of the isolates. Our research suggests that there may be a critical control point in the chilling room, and the high MDR rate and strong BFA increase the difficulty of control and the risk of transmission.

金黄色葡萄球菌(S. aureus)是一种常见的人畜共患食源性病原体,对肉类加工过程中的微生物控制构成严重威胁,尤其是耐多药(MDR)菌株。本研究旨在调查从中国两家牛肉加工厂分离的金黄色葡萄球菌的感染率、抗菌药敏感性、毒力基因、生物膜形成能力(BFA)和分子类型。结果显示,金黄色葡萄球菌的感染率为 17.1%(60/350),其中包括一株耐甲氧西林菌株。在七个采样点中,冷藏胴体的检出率最高。分离菌株对青霉素(88.3%)和林可霉素(80.0%)具有高度耐药性,75.0%的分离菌株对多种药物(MDR)具有耐药性。所有分离株都携带 hla 和 clfa 基因,还检测到关键毒素基因(seb、pvl 和 tst)。此外,96.7%的分离物表现出强和中度BFA。分离物采用多焦点序列分型法(MLST)和葡萄球菌蛋白 A(spa)分型法进行分型,每种方法可分出九种不同类型。最主要的类型是 ST7-t091,占分离株的 68.3%。我们的研究表明,冷藏室可能存在一个关键控制点,高 MDR 率和强 BFA 增加了控制难度和传播风险。
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引用次数: 0
Recent insight on nutritional value, active phytochemicals, and health-enhancing characteristics of fig (Ficus craica) 对无花果营养价值、活性植物化学物质和增强健康特性的最新认识
Pub Date : 2024-01-17 DOI: 10.1002/fsh3.12034
Manar Yahya Alzahrani, Asmaa Ibrahim Alshaikhi, Jumanah Samir Hazzazi, Jumanah Reda Kurdi, Mohamed Fawzy Ramadan

The current review highlights the nutritional values, phytochemical profile, and health-enhancing characteristics of figs (Ficus carica L., family Moraceae). Ficus carica is one of the oldest fruit trees. The fruit has been appreciated as food and for its biomedical properties since ancient times. Ficus carica contains essential bioactive compounds that enhance health. The plant is characterized by unique compounds in all parts (peel, pulp, leaves, seed, and latex) besides primary nutrients (fatty acids, carbohydrates, vitamins, and minerals). Ficus carica is rich in bioactive secondary products such as flavonoids, furanocoumarin, anthocyanin, pectin, and phytosterols, contributing to many health benefits. Bioactive phytonutrients found in fig are used as antioxidant and antidiabetic agents due to the presence of specific functional groups that control diabetes. The health-enhancing effects of fig, including anti-tumor, anti-inflammatory, and anti-osteoporosis, are related to high levels of minerals essential to bone health and their benefits on Alzheimer's disease. All parts of Ficus carica have been used in cosmetics and pharmaceutical products, especially wound healing. In addition, Ficus carica has many uses in food items as a colorant and a preservative. To the best of knowledge, there is a lack of reports discussing the biochemistry, bioactivity, and medicinal traits of Ficus carica and the plant parts. This review gathered scientific information regarding the chemical profile, biological traits, and different uses of Ficus carica.

本综述重点介绍了无花果(桑科榕属植物)的营养价值、植物化学成分和增强健康的特性。无花果是最古老的果树之一。自古以来,无花果就被人们作为食物和生物医药而受到青睐。榕树含有重要的生物活性化合物,能增强人体健康。除主要营养成分(脂肪酸、碳水化合物、维生素和矿物质)外,榕树各部分(果皮、果肉、叶子、种子和乳汁)都含有独特的化合物。榕树富含生物活性次生产品,如黄酮类、呋喃香豆素、花青素、果胶和植物甾醇,对健康有许多益处。无花果中的生物活性植物营养素可用作抗氧化剂和抗糖尿病剂,因为其中含有控制糖尿病的特定功能基团。无花果的保健作用包括抗肿瘤、抗炎和抗骨质疏松症,这与无花果含有大量对骨骼健康至关重要的矿物质以及对老年痴呆症的益处有关。榕树的所有部分都被用于化妆品和医药产品,特别是伤口愈合。此外,榕树还在食品中用作着色剂和防腐剂。据我所知,目前还缺乏有关榕树及其植物部分的生物化学、生物活性和药用特性的报道。本综述收集了有关榕树的化学成分、生物特性和不同用途的科学信息。
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Food Safety and Health
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