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Physicochemical, Sensory, Textural, Nutritional, and Antioxidant Properties of Bun From Wheat Flour Fortified With Galgal Peel Powder 加了藻皮粉的小麦粉馒头的理化、感官、质地、营养和抗氧化特性
Pub Date : 2025-07-24 DOI: 10.1002/fsh3.70032
Kalpana, Suhail Ahmad Bhat, Tanuja Srivastava

The present study investigated the incorporation of galgal (Citrus pseudolimon) peel powder (GPP) into wheat flour buns to improve their nutritional quality and antioxidant potential without compromising sensory acceptability. The objective was to determine whether GPP could enhance dietary fiber content and antioxidant capacity without adversely affecting product quality. Buns were formulated with 2%, 5%, 7%, and 10% GPP and evaluated for physicochemical, textural, sensory, nutritional, TPC, and antioxidant properties. Sensory evaluation by 12 semi-trained panelists indicated that buns containing up to 5% GPP were acceptable. Increasing GPP levels significantly increased hardness (N), chewiness (N·mm), and bulk density (g/cm3) while cohesiveness, springiness, and specific volume (cm3/g) decreased. Proximate analysis revealed an increase in dietary fiber and reductions in crude protein, crude fat, and water activity (aw). TPC (mg GAE/100 g) increased significantly, reflecting a higher polyphenol concentration. Antioxidant activity, assessed via DPPH (%) and FRAP (μM Fe2+/g) assays, also increased significantly with higher GPP levels. These findings highlight the potential of galgal peel as a sustainable health-promoting functional ingredient, supporting the development of value-added bakery products that address public health nutrition and food waste reduction, thereby contributing to broader societal goals of health improvement and sustainable food systems.

本文研究了在小麦粉馒头中添加假柠檬果皮粉(GPP),在不影响感官接受度的情况下,提高其营养品质和抗氧化能力。目的是确定GPP是否可以在不影响产品质量的情况下提高膳食纤维含量和抗氧化能力。分别以2%、5%、7%和10%的GPP配制面包,并对其理化、质地、感官、营养、TPC和抗氧化性能进行评价。12名半培训小组成员的感官评估表明,含有高达5% GPP的馒头是可以接受的。增加GPP水平显著提高了硬度(N)、咀嚼性(N·mm)和容重(g/cm3),而黏结性、弹性和比容(cm3/g)降低。近似分析显示,膳食纤维增加,粗蛋白质、粗脂肪和水活性(aw)降低。TPC (mg GAE/100 g)显著升高,多酚浓度升高。通过DPPH(%)和FRAP (μM Fe2+/g)测定,抗氧化活性也随着GPP水平的升高而显著增加。这些发现突出了藻皮作为可持续健康促进功能成分的潜力,支持开发解决公共卫生营养和减少食物浪费的增值烘焙产品,从而为改善健康和可持续粮食系统的更广泛社会目标做出贡献。
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引用次数: 0
Impact of Endocrine-Disrupting Chemicals (EDCs) Used in the Food Industry on Endocrine Abnormalities 食品工业中使用的内分泌干扰物(EDCs)对内分泌异常的影响
Pub Date : 2025-07-22 DOI: 10.1002/fsh3.70033
Perla D. Serrano-López, Frida B. Ocampo-Juárez, Alexandra Magaña-Rodríguez, José A. Téllez-Morales

The objective of this review was to examine the relationship between hormone disruption and other endocrine abnormalities in the context of the constant consumption of genetically modified foods and overexposure to chemicals used directly and indirectly in the agrifood industry. This review collates data pertinent to endocrine health and its correlation with dietary intake and the chemical substances that come into contact with food, including pesticides. We hypothesized that the changes caused by genetically modified organisms (GMOs) may have metabolic effects in the medium and long term, such as the proliferation of adipose tissue. Importantly, the scientific evidence on which we can rely has different slopes due to the types of studies and experiments necessary to verify them, as is the case for metabolic disorders, cancers of the gastrointestinal tract, and GMOs. Finally, it is imperative to acknowledge that the repercussions of disruptive compounds—which encompass, but are not limited to, pesticides and genetically modified organism derivatives—require additional investigation.

本综述的目的是研究在持续食用转基因食品和过度接触农业食品工业中直接或间接使用的化学品的情况下,激素紊乱与其他内分泌异常之间的关系。本综述整理了有关内分泌健康及其与饮食摄入和与食物接触的化学物质(包括农药)之间关系的数据。我们假设转基因生物(gmo)引起的变化可能在中长期内产生代谢影响,例如脂肪组织的增殖。重要的是,我们可以依赖的科学证据由于验证它们所需的研究和实验的类型而具有不同的倾斜度,就像代谢紊乱、胃肠道癌症和转基因生物的情况一样。最后,必须承认破坏性化合物——包括但不限于杀虫剂和转基因生物衍生物——的影响需要进一步的调查。
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引用次数: 0
Microplastic Contamination of Dairy and Bakery Products: Sources and Effects on Human Health—A Review 乳制品和烘焙食品的微塑料污染:来源及其对人体健康的影响
Pub Date : 2025-07-15 DOI: 10.1002/fsh3.70031
Anish Dangal, Sangam Dahal, Prekshya Timsina, Khan Irfan Khan, Annalisa Romano, Angelo Maria Giuffrè, Dev Raj Acharya, Kishor Rai, Elena Benedetta Baroncelli, Navin Gautam, Himalaya Ghimire

The widespread environmental presence of microplastics and their ability to enter the food chain are resulting in food contamination by these particles, which has been a serious health problem for the public. Products often consumed in the dairy and bakery industries are becoming more vulnerable to contamination by microplastics that come from packaging, processing, and the environment. The new findings of the studies on the long-term health impacts due to the ingestion of microplastics point to some serious health hazards. The findings of analyses on the availability of microplastics in dairy and bakery products are summarized in this review paper, along with the sources of contamination, classification of microplastics, and their health impact. This paper can present an overview for future studies on contamination of dairy and bakery products by microplastics, which is important for the strategies to reduce the contamination of the two top-growing food sectors.

微塑料在环境中的广泛存在及其进入食物链的能力导致这些颗粒污染食品,这已成为公众的严重健康问题。乳制品和烘焙行业经常消费的产品越来越容易受到来自包装、加工和环境的微塑料污染。关于摄入微塑料对健康的长期影响的研究的新发现指出了一些严重的健康危害。本文综述了对乳制品和烘焙产品中微塑料可用性的分析结果,以及微塑料的污染源、分类及其对健康的影响。本文概述了微塑料对乳制品和烘焙产品污染的未来研究,这对减少这两个主要食品部门污染的策略具有重要意义。
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引用次数: 0
Understanding the Concepts of Smart E-Nose Technology in Combination With Machine Learning for New Era of Food Safety: An Advanced Review 理解智能电子鼻技术与机器学习在食品安全新时代中的概念:进展综述
Pub Date : 2025-07-14 DOI: 10.1002/fsh3.70029
Poornima Singh, Umme Habiba, Zaryab Shafi, Aman Noor, Vinay Kumar Pandey, Rahul Singh

Electronic-nose (E-Nose) technology delivers fast and precise detection of volatile substances by utilizing sophisticated data processing techniques such as principal component analysis (PCA) and artificial neural networks (ANN). This makes E-Nose technology a useful substitute for conventional sensory evaluation methods. E-Nose systems are now even more capable because of the incorporation of artificial intelligence, which allows for complex pattern recognition and odor classification. Ongoing developments in sensor technology and data processing algorithms are anticipated to cement the position of E-Nose systems as crucial instruments in guaranteeing food safety, environmental health, and precise medical diagnostics, notwithstanding obstacles associated with sensor stability and environmental sensitivity. This technology's future depends on ongoing innovation and improvement in analytical techniques as well as sensor designs. E-Nose technology has shown great potential in some fields, including medical diagnostics, environmental monitoring, and food quality evaluation. This is especially true when combined with machine learning. The development of E-Nose systems from large power-hungry equipment to small, lightweight, and effective gadgets is examined in this research study.

电子鼻(E-Nose)技术通过利用复杂的数据处理技术,如主成分分析(PCA)和人工神经网络(ANN),提供快速和精确的挥发性物质检测。这使得电子鼻技术成为传统感官评估方法的有用替代品。由于人工智能的结合,电子鼻系统现在更加强大,可以进行复杂的模式识别和气味分类。传感器技术和数据处理算法的持续发展预计将巩固电子鼻系统作为保证食品安全、环境健康和精确医疗诊断的关键工具的地位,尽管存在与传感器稳定性和环境敏感性相关的障碍。这项技术的未来取决于分析技术和传感器设计的持续创新和改进。电子鼻技术在医疗诊断、环境监测和食品质量评价等领域显示出巨大的潜力。当与机器学习相结合时尤其如此。电子鼻系统的发展,从大型耗电设备到小,轻,有效的小工具,在这个研究研究中进行了检查。
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引用次数: 0
Comparative Analysis of Differential Metabolites in Panax quinquefolius From China and the United States Using UPLC-Orbitrap-MS and LC-MS/MS UPLC-Orbitrap-MS和LC-MS/MS对中美西洋参代谢物差异的比较分析
Pub Date : 2025-07-14 DOI: 10.1002/fsh3.70030
Dan Li, Ling Xie, Fan Li, Haoran Li, Zhipeng Zhang, Yi Peng, Liang Gong

Currently, there is a relative paucity of comparative studies on the metabolites of American ginseng from different geographical sources. This study aims to employ untargeted and targeted metabolomics to compare the variations in metabolites among Panax quinquefolius from Northeast China, Shandong, and the United States. In untargeted metabolomics analysis, a total of 1276 metabolites were identified, with 31 shared biomarker metabolites found in the P. quinquefolius samples. Further KEGG annotation and pathway enrichment analysis revealed 81 chemical classifications, with 4-year-old (DB4) ginseng from Northeast China primarily enriched in fatty acyls, whereas 4-year-old (MG4) American ginseng from the United States was mainly enriched in glycerophospholipids and prenol lipids. Arginine biosynthesis, as well as pantothenate and CoA biosynthesis, was significantly involved in the distinction between DB4 and MG4. Quantitative analysis of 25 polyphenolic compounds in DB4, 4-year-old (SD4) American ginseng from Shandong Province in China, and MG4 through targeted metabolomics unveiled that trans-ferulic acid, sinapic acid, kaempferol-3-O-glucoside, and (+)-dihydrokaempferol can be used to distinguish American ginseng from Chinese ginseng. Furthermore, trans-ferulic acid, 3,4-dihydroxybenzoic acid, and octanoic acid can serve as markers to differentiate ginseng from Northeast China and Shandong. These findings reveal the distinctive metabolic characteristics and phenolic components of P. quinquefolius, providing valuable insights for determining its geographical origin and enhancing quality control.

目前,对不同产地西洋参代谢产物的比较研究相对较少。本研究旨在采用非靶向代谢组学和靶向代谢组学方法比较东北、山东和美国西洋参代谢物的差异。在非靶向代谢组学分析中,共鉴定出1276种代谢物,其中31种共同的生物标志物代谢物在西西北风样品中被发现。进一步的KEGG注释和途径富集分析揭示了81种化学分类,东北4年生(DB4)人参主要富集于脂肪酰基,而美国4年生(MG4)西参则主要富集于甘油磷脂和丙烯醇脂。精氨酸的生物合成以及泛酸和辅酶a的生物合成与DB4和MG4的区别有显著关系。利用靶向代谢组学方法对山东4年生西洋参DB4、SD4和MG4中的25种多酚类化合物进行定量分析,发现反式阿魏酸、辛酸、山奈酚-3- o -葡萄糖苷和(+)-二氢山奈酚可用于区分西洋参和人参。反式阿魏酸、3,4-二羟基苯甲酸和辛酸可以作为东北人参和山东人参的鉴别标志。这些发现揭示了西洋参独特的代谢特征和酚类成分,为确定西洋参的产地和加强西洋参的质量控制提供了有价值的见解。
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引用次数: 0
Antimicrobial Susceptibility Profile of Escherichia coli Isolates From Artisanal Colonial Cheese in Southern Brazil 巴西南部手工殖民奶酪中大肠埃希菌的耐药性分析
Pub Date : 2025-06-28 DOI: 10.1002/fsh3.70028
Luísa Aimée Schmitt Lobe, Vanessa Cortina Zanetti, Natália Regina Coldebella Ferreira, Matheus Viapiana Frutuoso, Isadora Caroline Marian, Emanueli Marchesan Maran, Manuela Maggiora Freitas Bastos, Julia Eduarda Munaretto, Gustavo Rocha, Mateus Rocha Ribas, Victor Felipe Wolleck, Francisco Lucas Amorim Nascimento, Jussara Kasuko Palmeiro, Marília Miotto-Lindner, Silvani Verruck

Artisan colonial cheese (ACC), a key part of Brazilian culture, is made using traditional methods without pasteurization, which increases the risk of contamination by harmful bacteria such as some strains of Escherichia coli (E. coli). The widespread use of antimicrobials in recent decades has led to the emergence of E. coli strains resistant to multiple drugs. This resistance is concerning, especially in food products made using nonindustrial methods. To address this, phenotypic and genotypic methods are needed to identify resistant strains. This study aimed to address the antimicrobial resistance of E. coli strains from ACC in western Santa Catarina to 16 antimicrobials of clinical importance using the Kirby–Bauer method. Of the 116 isolates, 60% were multiresistant. Resistance was found in 93% of the tested antibiotics, with amikacin showing the highest resistance rate (38%). Imipenem was the only antibiotic effective against all isolates. Four isolates (3.4%) tested positive for the blaTEM and tetB resistance genes, but no carbapenemase-producing strains were found. This study emphasizes the importance of controlling antimicrobial use and developing new technologies to address resistant bacteria in food, as these strains pose risks to both human and animal health.

手工殖民奶酪(ACC)是巴西文化的重要组成部分,它使用传统方法制作,没有经过巴氏消毒,这增加了被某些大肠杆菌(E. coli)菌株等有害细菌污染的风险。近几十年来,抗菌素的广泛使用导致了对多种药物具有耐药性的大肠杆菌菌株的出现。这种耐药性令人担忧,特别是在使用非工业方法生产的食品中。为了解决这一问题,需要采用表型和基因型方法来鉴定耐药菌株。本研究旨在利用Kirby-Bauer方法研究圣卡塔琳娜州西部地区ACC大肠杆菌菌株对16种临床重要抗菌素的耐药性。在116株菌株中,60%具有多重耐药。在93%的测试抗生素中发现耐药性,阿米卡星的耐药率最高(38%)。亚胺培南是唯一对所有菌株有效的抗生素。4株(3.4%)检测到blaTEM和tetB耐药基因阳性,未发现产碳青霉烯酶菌株。这项研究强调了控制抗菌素使用和开发新技术以解决食品中耐药细菌的重要性,因为这些菌株对人类和动物健康都构成风险。
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引用次数: 0
Study on the Preparation of Citrus Essential Oil Microemulsion and Its Effect on the Preservation of Fresh-Cut Apples 柑桔精油微乳的制备及其对鲜切苹果保鲜效果的研究
Pub Date : 2025-06-17 DOI: 10.1002/fsh3.70026
Xinyu Feng, Meng Qi, Xiaoshuang Zheng, Jun Guo

Citrus essential oil was used as the primary material in this investigation, with Tween 80 as the surfactant and ethanol serving as a cosurfactant. Using the low-energy emulsification method to prepare citrus essential oil microemulsions (CEO-M) with high water solubility and stability. The optimal formulation was identified as citrus essential oil: mixed surfactant = 2:8, with a mixed surfactant ratio of Tween 80 to ethanol of 3:1 after examining the particle size, PDI, and zeta potential of the microemulsion. When the essential oil concentration reached 60 mg/mL, the ABTS+ and DPPH radical scavenging abilities of the CEO-M were 1.34 times and 1.22 times than that of the CEO-C, respectively. After 8 days of storage, CEO-M-treated fresh-cut apples lost much less weight, softness, titratable acid content, and soluble solids than controls. Browning index (BI) in CEO-M-treated apples (44.42%) was significantly attenuated relative to controls (69.28%) and the CEO-C treated group (54.01%) (p < 0.05). The CEO-M treatment greatly lowered the activities of polyphenol oxidase (PPO), peroxidase (POD), and the consumption of total phenolic content in fresh-cut apples. It inhibited the browning of the fruit. At the end of storage, the sensory scores of CEO-M were significantly higher than those of the control and CEO-C treatment groups.

本研究以柑橘精油为主要原料,以吐温80为表面活性剂,乙醇为助表面活性剂。采用低能乳化法制备高水溶性、高稳定性的柑桔精油微乳(CEO-M)。通过考察微乳液的粒径、PDI和zeta电位,确定最佳配方为柑橘精油:混合表面活性剂= 2:8,Tween 80与乙醇的混合比例为3:1。当精油浓度达到60 mg/mL时,CEO-M对ABTS+和DPPH自由基的清除能力分别是CEO-C的1.34倍和1.22倍。经过8天的储藏,经ceo - m处理的鲜切苹果的重量、柔软度、可滴定酸含量和可溶性固形物的损失都比对照组小得多。ceo - m处理的苹果褐变指数(BI)(44.42%)较对照组(69.28%)和CEO-C处理组(54.01%)显著降低(p < 0.05)。CEO-M处理显著降低了鲜切苹果多酚氧化酶(PPO)、过氧化物酶(POD)活性和总酚含量的消耗。它抑制了水果的褐变。贮藏结束时,CEO-M组的感官评分显著高于对照组和CEO-C处理组。
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引用次数: 0
Exploring the Antidiabetic and Lipid-Lowering Properties of Nepali Wild Turmeric (Curcuma aromatica): A Potential Natural Remedy 探索尼泊尔野生姜黄(Curcuma aromatica)的抗糖尿病和降脂特性:一种潜在的自然疗法
Pub Date : 2025-06-15 DOI: 10.1002/fsh3.70027
Salma Khadka, Tshoisang Vaal, Sanjit Gurung, Keshav Dhakal, Ramesh Raj Padhaya, Sailendra Chaudhary, Bipindra Pandey

In 2019, diabetes mellitus resulted in significant suffering in 9.3% of the global population, accounting for one in nine adult fatalities. The objective of this study was to use aqueous and ethanolic extracts of wild turmeric (Curcuma aromatica) rhizomes for phytochemical screening and to evaluate in vivo oral hypolipidemic and antidiabetic activities in both normal and alloxan-induced diabetic rats. Diabetes was induced using alloxan monohydrate to examine the effects on blood glucose and lipids. Diabetic and nondiabetic rats received ethanolic and aqueous (200 and 400 mg/kg) extracts for 21 days. The group of untreated diabetic individuals exhibited a significant increase (p < 0.001) in blood glucose, total cholesterol, and triglyceride levels, alongside a reduction (p < 0.05) in high-density lipoprotein (HDL) levels and body weight. After a 21-day treatment period, ethanolic extracts from Curcuma aromatica rhizomes at a dose of 400 mg/kg showed significantly (p < 0.001) decreased blood glucose levels and improved lipid profiles, thereby normalizing these parameters and preventing weight loss in diabetic rats as compared to the other group. Curcuma aromatica rhizome ethanolic extract shows significant antidiabetic properties, supporting its traditional use and potential for diabetes treatments. Further studies on active constituents and their antidiabetic mechanisms are needed.

2019年,糖尿病导致全球9.3%的人口遭受严重痛苦,占成人死亡人数的九分之一。本研究的目的是利用野生姜黄根茎的水提取物和乙醇提取物进行植物化学筛选,并评估正常和四氧嗪诱导的糖尿病大鼠的体内口服降血脂和抗糖尿病活性。用一水四氧嘧啶诱导糖尿病,观察其对血糖和血脂的影响。糖尿病大鼠和非糖尿病大鼠分别给予乙醇和水(200和400 mg/kg)提取物21天。未经治疗的糖尿病患者组血糖、总胆固醇和甘油三酯水平显著升高(p < 0.001),高密度脂蛋白(HDL)水平和体重显著降低(p < 0.05)。经过21天的治疗期,与另一组相比,400 mg/kg剂量的姜黄根茎乙醇提取物显著(p < 0.001)降低了糖尿病大鼠的血糖水平,改善了血脂,从而使这些参数正常化,并防止了体重减轻。姜黄乙醇提取物显示出显著的抗糖尿病特性,支持其传统用途和治疗糖尿病的潜力。有效成分及其抗糖尿病机制有待进一步研究。
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引用次数: 0
Using Probiotic Consortium to Poultry Feed as a Substitute for Antibiotic Growth Promoters 益生菌联合体在家禽饲料中替代抗生素生长促进剂的研究
Pub Date : 2025-06-06 DOI: 10.1002/fsh3.70025
Md. Nur Hossain, Saifa Sharmin, Md. Mizanur Rahaman, Md. Masud Rana, Md. Fakruddin, Monzur Morshed Ahmed

Antibiotic growth promoters (AGPs), once integral to poultry feed formulations for their growth-enhancing properties, are increasingly associated with the emergence of antibiotic-resistant strains, posing a significant threat to animal and human health. In response to this critical challenge, this research article explores the transformative potential of probiotic-enriched feed as a sustainable alternative to AGPs in promoting growth in poultry. Three potential probiotic strains (Saccharomyces cerevisiae IFST062013, Lactiplantibacillus pentosus BDIFST24010, and Lactiplantibacillus plantarum BDIFST24009) were included in this study and their probiotic attributes were determined. Probiotic-enriched feed was formulated, and the field trial was conducted on broiler chicken. The isolates showed a good tolerance to acidic pH, bile salts, gastric juice, and showed good antimicrobial activities against pathogens. The isolates were more heat stable to make starter fed and sufficient cell counts was observed after 10 months of storage at 4°C. No significant difference was found between antibiotic and probiotics supplementation, but fat deposition in abdominal area was found in an antibiotic group compared to the probiotic group. In conclusion, the probiotic supplement developed is quite promising, but further field studies are required to more conclusive results before replacing antibiotic growth promoters aligning with contemporary imperatives for responsible agriculture and global health.

抗生素生长促进剂(AGPs)曾因其促进生长的特性而成为家禽饲料配方中不可或缺的一部分,但现在却日益与耐抗生素菌株的出现联系在一起,对动物和人类健康构成重大威胁。为了应对这一关键挑战,本研究探讨了益生菌强化饲料作为agp的可持续替代品在促进家禽生长方面的变革潜力。本研究选取了3株潜在益生菌(酿酒酵母菌IFST062013、乳酸菌BDIFST24010和植物乳酸菌BDIFST24009)作为研究对象,并对其益生菌特性进行了测定。配制了益生菌强化饲料,并在肉鸡上进行了田间试验。菌株对酸性pH、胆盐、胃液具有良好的耐受性,对病原菌具有良好的抑菌活性。分离株的热稳定性较好,可以作为起始饲料,在4℃下储存10个月后观察到足够的细胞计数。抗生素组和益生菌组之间没有发现显著差异,但与益生菌组相比,抗生素组腹部脂肪沉积明显。总之,开发的益生菌补充剂很有前景,但在取代抗生素生长促进剂之前,还需要进一步的实地研究来获得更确切的结果,以符合当代负责任的农业和全球健康的要求。
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引用次数: 0
Metabolomics Assessment of the Mitigation of Lead-Induced Inflammation in Adult Zebrafish (Danio rerio) by a Fermented Soybean Extract 发酵大豆提取物缓解成年斑马鱼(Danio rerio)铅诱导炎症的代谢组学评估
Pub Date : 2025-06-04 DOI: 10.1002/fsh3.70024
Siok-Geok Chong, Intan Safinar Ismail

This study investigated the potential of fermented soybean extract (FSE) as an alternative therapy for lead (Pb) toxicity, without chelation side effects. This study is crucial for developing safe and effective treatments for patients with low Pb toxicity. Preliminary experiments were conducted using FSE concentrations ranging from 0 to 300 mg/L before evaluating their therapeutic effect against Pb-induced inflammation in the zebrafish model. Multivariate data analysis was employed, along with transmission electron microscopy (TEM) for the 300 mg/L treatment group. The 50 mg/L group significantly altered four metabolites, namely, sn-glycerol-3-phosphocholine, glucose, isoleucine, and glutamine, without necrosis-like cell death in TEM results such as observed in the 300 mg/L group. Citrulline increased in the untreated Pb group, but not in the FSE and DMSA treatment groups, suggesting retrieval of toxicity. This study highlights the potential of FSE as a therapeutic option for mitigating Pb toxicity, offering insight into food interventions in toxicology.

本研究探讨了发酵大豆提取物(FSE)作为无螯合副作用的铅(Pb)毒性替代疗法的潜力。本研究对开发安全有效的低铅中毒治疗方法具有重要意义。在斑马鱼模型中,使用浓度为0 ~ 300 mg/L的FSE进行初步实验,然后评估其对pb诱导炎症的治疗效果。300 mg/L处理组采用多变量数据分析及透射电镜(TEM)观察。50 mg/L组显著改变了4种代谢物,即-甘油-3-磷酸胆碱、葡萄糖、异亮氨酸和谷氨酰胺,TEM结果未见300 mg/L组观察到的坏死样细胞死亡。瓜氨酸在未处理的Pb组中升高,但在FSE和DMSA处理组中没有升高,提示毒性恢复。本研究强调了FSE作为减轻铅毒性的治疗选择的潜力,为毒理学中的食物干预提供了见解。
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引用次数: 0
期刊
Food Safety and Health
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