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Egg white grafts weak-gels efficiently stabilize high internal phase emulsions and interfere with lipid hydrolysis: As delivery vehicles for hydrophobic actives 蛋白接枝弱凝胶能有效稳定高内相乳液并干扰脂质水解:作为疏水性活性物质的输送载体
Pub Date : 2024-07-27 DOI: 10.1002/fsh3.12057
Mingyue Yang, Nan Xiao, Shanguang Guo, Minmin Ai

This study investigated the performance of egg white grafts (EWG) weak-gel to stabilize high internal phase emulsions (HIPEs) loaded with curcumin and analyzed the lipids hydrolysis after digestion via proton nuclear magnetic resonance 1H NMR. The results showed that the EWG weak-gel formed after heating stabilized HIPEs exhibited small particle sizes, high values of storage and loss modulus, and a compact microstructure as well as better environmental stability. The stability of curcumin encapsulated in HIPEs stabilized by EWG weak-gel was increased by 1.80-fold. In in vitro simulation of digestion, the release of free fatty acids by HIPEs decreased from 89.59% to 31.85% with the increasing EWG weak-gel proportion. Based on the results of 1H NMR analysis, unsaturated lipids are less susceptible to hydrolysis and oxidation as they are protected by a thicker interfacial layer formed by the EWG weak-gel formed after heating. Hence, the EWG weak-gel can stabilize HIPEs and deliver hydrophobic bioactive compounds efficiently and interfere with lipids hydrolysis.

本研究考察了蛋白接枝(EWG)弱凝胶稳定负载姜黄素的高内相乳液(HIPE)的性能,并通过质子核磁共振 1H NMR 分析了消化后的脂质水解情况。结果表明,加热稳定 HIPE 后形成的 EWG 弱凝胶具有较小的粒径、较高的储存模量和损失模量值、紧凑的微观结构以及较好的环境稳定性。经 EWG 弱凝胶稳定化的 HIPE 中封装的姜黄素的稳定性提高了 1.80 倍。在体外模拟消化中,随着 EWG 弱凝胶比例的增加,HIPEs 释放的游离脂肪酸从 89.59% 降至 31.85%。根据 1H NMR 分析结果,不饱和脂质在加热后形成的 EWG 弱凝胶所形成的较厚界面层的保护下,不易水解和氧化。因此,EWG 弱凝胶可以稳定 HIPE,有效输送疏水性生物活性化合物,并干扰脂质水解。
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引用次数: 0
Salt reduction strategies and enhanced saltiness perception mechanisms for prepared dishes: A review 预制菜肴的减盐策略和增强咸味感知机制:综述
Pub Date : 2024-07-09 DOI: 10.1002/fsh3.12055
Haijing Lan, Lei Chen

Healthy prepared dishes are receiving increasing attention, with high salt content being their prominent feature, and a long-term high sodium diet may lead to various diseases. At present, replacing NaCl with non-sodium salts has become the main salt reduction method, but these substitutes will bring adverse flavors to the product, and excessive use of KCl will also affect health. Therefore, the study of flavor peptides combined with new green technologies is a potentially effective strategy to reduce salt without reducing saltiness. This article reviews the current salt reduction strategies, the effects of food matrix, basic amino acids, other tastes and odors on saltiness, and the relationship between saltiness and receptor structure and transduction mechanism. In addition, the saltiness assessment methods were introduced, and the current challenges faced by the strategy of reducing salt without reducing saltiness were discussed. The preparation of salty peptides and salty enhancing peptides from natural foods and the combination of them with new green technologies may be an effective method for salt reduction in the food industry. This review can provide theoretical reference for the prepared dishes industry to reduce salt without reducing saltiness.

健康烹饪菜肴越来越受到人们的关注,高盐是其突出特点,长期高钠饮食可能导致各种疾病。目前,用非钠盐替代氯化钠已成为主要的减盐方法,但这些替代品会给产品带来不良风味,过量使用氯化钾也会影响健康。因此,风味肽的研究与新型绿色技术相结合,是一种在不降低咸度的前提下减少食盐的潜在有效策略。本文综述了当前的减盐策略,食品基质、基础氨基酸、其他味道和气味对咸味的影响,以及咸味与受体结构和传导机制之间的关系。此外,还介绍了咸味评估方法,并讨论了当前减盐不减咸味策略所面临的挑战。从天然食品中制备咸味肽和增咸肽,并将其与新型绿色技术相结合,可能是食品工业减盐的有效方法。本综述可为预制菜肴行业在不降低咸度的情况下减少盐分提供理论参考。
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引用次数: 0
Comprehensive analysis of the metabolic nutritional components and exploration of health-promoting small molecules in japonica rice and indica rice seeds 全面分析粳稻和籼稻种子中的代谢营养成分并探索促进健康的小分子物质
Pub Date : 2024-06-03 DOI: 10.1002/fsh3.12054
Mengjun Tian, Shaoyan Lin, Wenwen Huang, Wei Zhao, Junjie Tan, Ming Wang

The comprehensive detection of primary metabolites and secondary metabolites in japonica rice (Nipponbare) and indica rice seeds (93-11) were clarified by using a combination of targeted and untargeted metabolomics approaches we created. A total of 246 metabolites were identified, encompassing 4 primary metabolite classes (3 sugars, 6 organic acids, 21 amino acids, 5 lipids) and 3 secondary flavonoid metabolite classes (17 flavones, 2 flavonones, 4 flavonols), as well as various other secondary metabolites. We found that japonica rice contains higher levels of sugars (especially fructose), alanine, flavonols, and luteolin complexes, while indica rice contains higher levels of organic acids, amino acids (excluding alanine), flavanones, and apigenin and its complexes. Exploring and comparing the comprehensive nutritional composition of the two types of rice not only enabled individuals to choose their staple food according to their own physical condition but also provided new insights for the development of health-promoting rice.

利用我们创建的靶向和非靶向相结合的代谢组学方法,全面检测了粳稻(日本早稻)和籼稻(93-11)种子中的一级代谢物和二级代谢物。共鉴定出 246 种代谢物,包括 4 种一级代谢物(3 种糖类、6 种有机酸、21 种氨基酸、5 种脂类)和 3 种二级黄酮类代谢物(17 种黄酮、2 种黄酮、4 种黄酮醇),以及其他各种二级代谢物。我们发现,粳稻中糖类(尤其是果糖)、丙氨酸、黄酮醇和木犀草素复合物的含量较高,而籼稻中有机酸、氨基酸(不包括丙氨酸)、黄酮、芹菜素及其复合物的含量较高。探索和比较两种大米的综合营养成分,不仅能让人们根据自己的身体状况选择主食,也为开发有益健康的大米提供了新的思路。
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引用次数: 0
Guidelines for separation of natural extracellular vesicles 天然细胞外囊泡分离指南
Pub Date : 2024-05-30 DOI: 10.1002/fsh3.12049
Duo Liang, Yu Li, Jiaxuan Li, Shen Yang, Wentao Su

Extracellular vesicles (EVs) are found everywhere in different biofluids such as blood, saliva, urine, cerebrospinal fluid, and breast milk. They have sizes ranging from 20 to 400 nm and contain a wide range of cargo, including membrane proteins, periplasmic proteins, and nucleic acids. EVs possess the remarkable ability to diffuse, traverse the mucus layer, migrate directly to other tissues, and interact with various cells of the host immune system. Consequently, researchers have harnessed their potential as delivery carriers for novel immuno-drugs or bioactive components. The separation of EVs from food can be considered a safe and effective method for harnessing their beneficial effects. In this guide, we present isolation protocols for natural EVs derived from plants, dairy products, cells, and microbes. This includes steps for raw material processing or culture as well as conditions for separation and purification. Moreover, these protocols can serve as a foundation for preparing and isolating engineered EVs. In summary, the utilization of natural EVs presents a vast array of opportunities in the fields of biotechnology, biomedicine, and food nutrition.

细胞外囊泡(EVs)在血液、唾液、尿液、脑脊液和母乳等不同的生物流体中随处可见。它们的大小从 20 纳米到 400 纳米不等,含有多种货物,包括膜蛋白、周质蛋白和核酸。EVs具有卓越的扩散能力,可以穿过粘液层,直接迁移到其他组织,并与宿主免疫系统的各种细胞相互作用。因此,研究人员利用它们的潜力,将其作为新型免疫药物或生物活性成分的输送载体。从食物中分离 EVs 可以说是利用其有益作用的一种安全有效的方法。在本指南中,我们介绍了从植物、乳制品、细胞和微生物中提取天然 EVs 的分离方案。其中包括原材料加工或培养的步骤,以及分离和纯化的条件。此外,这些方案还可作为制备和分离工程 EVs 的基础。总之,天然 EVs 的利用为生物技术、生物医学和食品营养领域带来了大量机遇。
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引用次数: 0
Diabetic nephropathy: Ayur-nutri-pharmaco approach 糖尿病肾病:阿育王-营养素-药物疗法
Pub Date : 2024-05-21 DOI: 10.1002/fsh3.12048
Kounaina Khan, Subrahmanya Padyana

Prameha, described in Ayurveda, shares similarities with non-communicable lifestyle disorder Diabetes Mellitus. It is associated with an array of complications, referred to as “Upadrava” which can manifest in various organ systems. Among the complications, diabetic nephropathy (DN) stands out as a critical concern due to its impact on kidney health. Ayurveda views the body as an interplay of Doshas, and diabetes-related nephropathy is understood through the lens of “Prameha upadrava” which involves an imbalance of Doshas affecting kidney function. Ayurvedic treatment emphasizes personalized dietary adjustments, herbal remedies, lifestyle modifications, and mind-body practices, wherein the Modern therapeutic approaches include receptor mediated targeting, stem cell therapies, and dietary management. The current review aims for better insights, amalgamating the ailments and divergence between Ayurvedic and pharmacological perspectives on pathophysiology and management of DN. A dedicated effort has been initiated to identify the specific edible botanical elements mentioned as Pramehaghna in the Ayurvedic compendium, Bhavaprakash nighantu. A comprehensive evaluation of botanical entities was performed for a deeper understanding of their enumerated properties. The data pave newer avenues toward multidimensional-holistic approach to address the intricate complexities of DN leading to integrated approaches in Ayurveda, nutrition and pharmacology leading to better health and hygiene.

阿育吠陀中描述的 Prameha 与非传染性生活方式疾病糖尿病有相似之处。它与一系列并发症有关,这些并发症被称为 "Upadrava",可表现在多个器官系统。在这些并发症中,糖尿病肾病(DN)因其对肾脏健康的影响而备受关注。阿育吠陀将人体看作是多色性(Doshas)的相互作用,通过 "Prameha upadrava"(多色性失衡影响肾功能)的视角来理解与糖尿病相关的肾病。阿育吠陀疗法强调个性化饮食调整、草药疗法、生活方式调整和身心实践,而现代治疗方法包括受体介导靶向疗法、干细胞疗法和饮食管理。目前的综述旨在更好地了解、综合阿育吠陀疗法和药理学对 DN 的病理生理学和管理方面的分歧。我们已开始致力于确定阿育吠陀药典《Bhavaprakash nighantu》中作为 Pramehaghna 提到的特定可食用植物成分。对植物实体进行了全面评估,以深入了解其列举的特性。这些数据为采用多维-整体方法解决 DN 的复杂问题铺平了新的道路,从而在阿育吠陀学、营养学和药理学中采用综合方法,改善健康和卫生状况。
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引用次数: 0
Understanding the natural medicine pharmacology: A profile of Kefeng Zhai 了解天然药物药理学:翟克峰简介
Pub Date : 2024-05-20 DOI: 10.1002/fsh3.12045
Kefeng Zhai

As a pharmacology professor in the university, Kefeng Zhai is determined to become an educator. He received his bachelor's, master's, and doctor's degrees from the Anhui University of Chinese Medicine, Shihezi University, and China Pharmaceutical University, respectively. Dr. Zhai was born into a scholarly family. His father encouraged him all the time and influenced him to become an excellent teacher. Therefore, he often said: “I train talents for the school, is to train talents for the country, so that I can send more talents to the society.” After receiving his doctorate, Dr. Zhai came to Jinling Hospital of Nanjing University to begin his postdoctoral career. Six years later, Dr. Zhai enthusiastically came to work at Suzhou University, adhering to the original intention of contribution to the cause of education. He hopes that his deep cultivation in the education industry can train talents for society, contribute to the country's development, and teach more outstanding talents with correct values and scientific and cultural literacy. Over the past 16 years of practice, Dr. Zhai has not changed his mind, always adhered to establishing morality and cultivating people, and worked conscientiously in front-line posts.

“I entered Dr. Zhai's project group in my sophomore year. After joining the group, I found that Dr. Zhai's appearance differed from being strict. He not only helped me solve my academic problems, but also gave me life guidance. Dr. Zhai is a harsh and kind teacher”; “I am fortunate to meet Dr. Zhai, and I feel sincere and modest in him.” Two of his students spoke highly of him.

As a professional who delves into advanced science and technology, Dr. Zhai knows very well that it is not enough to just impart knowledge to students. Therefore, he fully used his time and devoted abundant energy to scientific research. Over the years, he actively promoted cooperation between universities and enterprises, conducted R&D work with many pharmaceutical enterprises in the city, and achieved good results. Through continuous exploration and study, Dr. Zhai is well aware that educators should always have the ambition of “serving the country.” Over the years, he has regarded education, scientific research, and exploration as his goals. He has achieved double harvests in education, science, and technology through solid hard work and meticulous research.

Dr. Zhai chose to research conventional Chinese medicine because traditional Chinese medicine and its active components are essential sources of new drug research and preparation, and it plays an essential role in innovative drug development. At present, Dr. Zhai is mainly engaged in research on the efficacy and mechanism of active components of traditional Chinese medicine, target identification and function of cardiovascular disease, miRNA regulation, evaluation, transformation of traditional Chinese medicine compound prescription, and so on. In addition, he also focuse

作为一名大学药理学教授,翟克峰立志成为一名教育家。他分别在安徽中医药大学、石河子大学和中国药科大学获得学士、硕士和博士学位。翟博士出生在一个书香门第。他的父亲一直鼓励他,影响他成为一名优秀的教师。因此,他经常说"我为学校培养人才,就是为国家培养人才,这样才能为社会输送更多的人才"。获得博士学位后,翟博士来到南京大学金陵医院开始了他的博士后生涯。6年后,翟博士满怀热情来到苏州大学工作,秉承着为教育事业做贡献的初心。他希望通过自己在教育行业的深耕,为社会培养人才,为国家发展贡献力量,教出更多具有正确价值观和科学文化素养的优秀人才。从教16年来,翟博士初心不改,始终坚持立德树人,在一线岗位上兢兢业业。进入课题组后,我发现翟博士的外表与严厉不同。他不仅帮助我解决学习上的问题,还给予我生活上的指导。翟博士是一位严厉而和蔼的老师";"我有幸遇到了翟博士,在他身上我感受到了真诚和谦虚"。作为一名钻研先进科学技术的专业人士,翟博士深知仅仅向学生传授知识是远远不够的。因此,他充分利用自己的时间,将充沛的精力投入到科研工作中。多年来,他积极推动校企合作,与我市多家医药企业开展研发工作,取得了良好的效果。通过不断的探索和研究,翟博士深知教育工作者要始终怀有 "报国 "之志。多年来,他把教育、科研、探索作为自己的奋斗目标。翟博士选择研究传统中药,是因为传统中药及其有效成分是新药研究和制备的重要来源,在创新药物开发中起着至关重要的作用。目前,翟博士主要从事中药有效成分的功效与作用机理、心血管疾病的靶点识别与作用、miRNA调控、评价、中药复方转化等方面的研究。此外,他还专注于心脑血管疾病临床生物标志物和治疗靶点的发现和研究,以及自身免疫性疾病的攻关。翟博士已发表论文80余篇,其中SCI论文40余篇,高被引论文2篇。翟博士不仅担任苏州大学生物与食品工程学院副院长,还担任皖北道地药材开发与高值化利用工程技术研究中心主任、中国少数民族医药学会常务理事、安徽省药学会理事、中国生物工程学会终身会员等职务。曾获中国发明协会发明创新奖二等奖、安徽省科技进步奖三等奖、淮海科学技术奖、中国少数民族医药学会科学技术奖等多个奖项。翟博士很早就意识到中医药在治病救人方面的独特性,并在当时就埋下了科研的梦想。多年来,他付诸实践,努力提高自己的科学文化素养,投身于中医药科研事业。"我一直认为自己与中医药有着不解之缘,中医药是我一生的追求。因为热爱,我希望能振兴中医药事业,所以一直在科研和教学上努力着。"这就是翟博士的人生追求。
{"title":"Understanding the natural medicine pharmacology: A profile of Kefeng Zhai","authors":"Kefeng Zhai","doi":"10.1002/fsh3.12045","DOIUrl":"10.1002/fsh3.12045","url":null,"abstract":"<p></p><p>As a pharmacology professor in the university, Kefeng Zhai is determined to become an educator. He received his bachelor's, master's, and doctor's degrees from the Anhui University of Chinese Medicine, Shihezi University, and China Pharmaceutical University, respectively. Dr. Zhai was born into a scholarly family. His father encouraged him all the time and influenced him to become an excellent teacher. Therefore, he often said: “I train talents for the school, is to train talents for the country, so that I can send more talents to the society.” After receiving his doctorate, Dr. Zhai came to Jinling Hospital of Nanjing University to begin his postdoctoral career. Six years later, Dr. Zhai enthusiastically came to work at Suzhou University, adhering to the original intention of contribution to the cause of education. He hopes that his deep cultivation in the education industry can train talents for society, contribute to the country's development, and teach more outstanding talents with correct values and scientific and cultural literacy. Over the past 16 years of practice, Dr. Zhai has not changed his mind, always adhered to establishing morality and cultivating people, and worked conscientiously in front-line posts.</p><p>“I entered Dr. Zhai's project group in my sophomore year. After joining the group, I found that Dr. Zhai's appearance differed from being strict. He not only helped me solve my academic problems, but also gave me life guidance. Dr. Zhai is a harsh and kind teacher”; “I am fortunate to meet Dr. Zhai, and I feel sincere and modest in him.” Two of his students spoke highly of him.</p><p>As a professional who delves into advanced science and technology, Dr. Zhai knows very well that it is not enough to just impart knowledge to students. Therefore, he fully used his time and devoted abundant energy to scientific research. Over the years, he actively promoted cooperation between universities and enterprises, conducted R&amp;D work with many pharmaceutical enterprises in the city, and achieved good results. Through continuous exploration and study, Dr. Zhai is well aware that educators should always have the ambition of “serving the country.” Over the years, he has regarded education, scientific research, and exploration as his goals. He has achieved double harvests in education, science, and technology through solid hard work and meticulous research.</p><p>Dr. Zhai chose to research conventional Chinese medicine because traditional Chinese medicine and its active components are essential sources of new drug research and preparation, and it plays an essential role in innovative drug development. At present, Dr. Zhai is mainly engaged in research on the efficacy and mechanism of active components of traditional Chinese medicine, target identification and function of cardiovascular disease, miRNA regulation, evaluation, transformation of traditional Chinese medicine compound prescription, and so on. In addition, he also focuse","PeriodicalId":100546,"journal":{"name":"Food Safety and Health","volume":"2 3","pages":"404-405"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsh3.12045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141123277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Profile of Dr. Dongxiao Su 苏东晓博士简介
Pub Date : 2024-05-17 DOI: 10.1002/fsh3.12046
Dongxiao Su

Dongxiao Su is a highly qualified food engineer with extensive knowledge in nutrition. He obtained his Bachelor's degree in Food Science and Engineering from the Huazhong Agricultural University in 2006, followed by a Master's degree and a PhD in Agricultural Product Processing and Storage Engineering from the same university in 2009 and 2014, respectively.

Since 2017, he has served as an associate professor and master's supervisor at the Guangzhou University. He has been recognized for his exceptional talent and selected as a high-level talent in Guangzhou City. Moreover, he is a distinguished member of the “Hundred Talents Plan” of Guangzhou University and the Youth Committee of the Guangdong Food Association. Furthermore, his expertise is highly valued as a member of the Expert Committee of the Guangdong Special Medical Purpose Formula Food Industry Technology Innovation Alliance.

His research focuses on fruit nutrition, gut microbiota, modern simplified food processing, and targeted sustained-release soft materials. The main objective is to evaluate the health effects and mechanisms of tropical to subtropical fruit resources and to develop related health products. Furthermore, his group is developing targeted sustained-release functional oleogel/emulsion with bioactive ingredients. He has successfully led projects for the National Natural Science Foundation General Project, National Natural Science Foundation Youth Project, Guangdong Provincial Natural Science Foundation, Hubei Provincial Natural Science Foundation, and others. With over 70 scientific research papers published, including in the Journal of Agriculture and Food Chemistry (which featured a cover article), Food Chemistry, Food & Function, and LWT. His expertise and competence are evident. Moreover, he has successfully applied for over 10 Chinese national invention patents, of which 6 have been granted. These achievements demonstrate his credibility and authority in the field.

苏东晓是一名高素质的食品工程师,拥有丰富的营养学知识。他于 2006 年获得华中农业大学食品科学与工程专业学士学位,随后分别于 2009 年和 2014 年获得该校农产品加工及贮藏工程专业硕士学位和博士学位。2017 年至今,他担任广州大学副教授、硕士生导师。他因才华出众,入选广州市高层次人才。此外,他还是广州大学 "百人计划 "和广东省食品协会青年委员会的杰出成员。他的研究重点是水果营养、肠道微生物群、现代简化食品加工和靶向缓释软性材料。他的研究重点是水果营养、肠道微生物群、现代简化食品加工和定向缓释软性材料,主要目标是评估热带和亚热带水果资源的保健作用和机理,并开发相关保健产品。此外,他的研究小组正在开发含有生物活性成分的定向缓释功能性油凝胶/乳液。他成功主持了国家自然科学基金一般项目、国家自然科学基金青年项目、广东省自然科学基金、湖北省自然科学基金等项目。在《农业与食品化学学报》(封面文章)、《食品化学》、《Food & Function》、《LWT》等刊物上发表科研论文 70 多篇。他的专业知识和能力有目共睹。此外,他还成功申请了 10 多项中国国家发明专利,其中 6 项已获授权。这些成就证明了他在该领域的可信度和权威性。
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引用次数: 0
Bold innovation driven by interdisciplinary collaboration: A profile of Jingjing Tian 跨学科合作推动大胆创新:田晶晶简介
Pub Date : 2024-05-07 DOI: 10.1002/fsh3.12047
Jingjing Tian

Dr. Jingjing Tian currently holds the position of lecturer at Nanjing Agricultural University. She also serves as a Secretary of the International Association of Dietetic Nutrition and Safety (http://www.iadns.cn/), and acts as Deputy Editor for eFood (https://onlinelibrary.wiley.com/journal/26663066). Her research is primarily focused on intelligent food processing and precision nutrition. As the lead author, Dr. Jingjing Tian has published papers in renowned journals, including Small, ACS Applied Materials & Interfaces, and Food Chemistry.

Beyond her scholarly pursuits of becoming a food chemist, Dr. Jingjing Tian aspires to excel as an academic editor. Her academic journey includes a bachelor's degree in Pharmaceutical Engineering from Hebei Agricultural University, a master's degree in Agricultural Products Processing and Storage Engineering from Beijing University of Agriculture, and a doctoral degree in Food Nutrition and Safety from China Agricultural University. Her interdisciplinary background fosters a holistic approach to research, and she expresses her keen interest in the dynamic nature of scientific inquiry: “My interdisciplinary education fuels my passion for staying abreast of the latest advancements in scientific research,” she notes.

During her undergraduate studies, she demonstrated exceptional proficiency in molecular biology and genetic engineering, achieving nearly perfect scores in her courses. In her master's program, she adeptly applied her knowledge to the expression of acetylcholinesterase in yeast cells, facilitating rapid detection of organophosphorus pesticides and gaining insight into the interdisciplinary allure of biotechnology in the realm of food science. Embarking on her doctoral journey, she delved into the realm of Functional Nucleic Acids, a core focus of her research. Expanding on her expertise, she explored rapid detection methods for food safety risk factors, integrating principles from chemistry, materials science, and nanotechnology into her investigations. Her interdisciplinary approach not only broadened the scope of food safety research but also cultivated a robust scientific mindset, characterized by resilience and a relentless pursuit of innovation. In the final years of her doctoral studies, she welcomed motherhood, a role that inspired her to push the boundaries of her research once again. Leveraging the concept of DNA Nanoflowers, she innovatively applied these functional nucleic acid elements to the field of nutrition and health (https://doi.org/10.1002/smll.202205933), devising targeted strategies for obesity prevention through the precise delivery of functional factors in food.

Upon assuming the role of lecturer in Nanjing Agricultural University, she seamlessly blended her academic expertise with interdisciplinary perspectives, driving forward scientific inquiry in intelligent food processing and precision nutri

田晶晶博士现任南京农业大学讲师。她还担任国际饮食营养与安全协会 (http://www.iadns.cn/) 的秘书,并担任 eFood (https://onlinelibrary.wiley.com/journal/26663066) 的副主编。她的研究主要集中在智能食品加工和精准营养方面。作为第一作者,田晶晶博士曾在《Small》、《ACS Applied Materials & Interfaces》和《Food Chemistry》等知名期刊上发表论文。她的学术历程包括获得河北农业大学制药工程学士学位、北京农业大学农产品加工与贮藏工程硕士学位以及中国农业大学食品营养与安全博士学位。她的跨学科背景培养了她全面的研究方法,她对科学探索的动态性质表现出浓厚的兴趣:她说:"跨学科教育激发了我的热情,使我能够紧跟科学研究的最新进展。"在本科学习期间,她在分子生物学和基因工程方面表现出了非凡的能力,她的课程几乎都是满分。在硕士课程中,她熟练地将所学知识应用于乙酰胆碱酯酶在酵母细胞中的表达,促进了有机磷农药的快速检测,并深入了解了生物技术在食品科学领域的跨学科魅力。在攻读博士学位的过程中,她深入研究了功能核酸领域,这是她研究的核心重点。她拓展专业知识,探索食品安全风险因素的快速检测方法,并将化学、材料科学和纳米技术的原理融入她的研究中。她的跨学科研究方法不仅拓宽了食品安全研究的范围,还培养了坚韧不拔、不懈追求创新的科学思维。在攻读博士学位的最后几年,她迎来了自己的母亲,这一角色再次激发了她的研究热情。她利用DNA纳米花的概念,创新性地将这些功能性核酸元素应用于营养与健康领域(https://doi.org/10.1002/smll.202205933),通过精确传递食品中的功能因子,设计出预防肥胖的针对性策略。在担任南京农业大学讲师后,她将自己的学术专长与跨学科视角完美融合,推动了智能食品加工和精准营养方面的科学探索。回顾自己的研究历程,她认为跨学科研究具有不可估量的价值,不仅促进了她的学术成就,还使她具备了担任学术期刊编辑所必需的批判性思维能力。祝愿她在学术追求和编辑工作中不断进步。
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引用次数: 0
The profile of Lingjun Ma 马灵骏简介
Pub Date : 2024-05-01 DOI: 10.1002/fsh3.12044
Lingjun Ma

Lingjun Ma, born in 1991, is an associate professor and doctoral supervisor at College of Food Science and Nutrition Engineering, China Agricultural University. She obtained Ph.D. degree from University of California, Davis, under the guidance of Prof. Andrew Waterhouse in 2017. She worked as a postdoctoral fellow in Prof. Richard Kibbey's lab at Yale University (2018–2019). She was invited to join China Agricultural University as an outstanding talent and associate professor in 2019. Since then, she devoted her research on polyphenol oxidation mediated reaction in foods, focusing on the quinone effects on color, flavor, safety, health effects, etc.

Dr. Ma has won the Young Elite Scientists Sponsorship Program by Chinese Association for Science and Technology, who is the only female scientist to get this honor in the area of food science and technology in China (2021); she also won the award in China Agricultural Science and Technology Services (2023); Outstanding Service Award on the International Symposium on Phytochemicals in Medicine and Food (ISPMF, 2023); Wiley Open Science Excellent Author (2021); The David E. Gallo Award (2015); and the best poster presentation in American Society for Enology and Viticulture (2017). She is the outstanding talent of China Agricultural University (2019–now); the Vice Secretary-General of International Association of Dietary Nutrition and Safety (2021–now); the expert on green food development in China (2021); a member of National Fruit and Vegetable Processing Engineering Technology Research Center (2019–now); a young editorial board member of Food Frontier (IF=9.9), e-Food (IF=7.425), Journal of Future Foods, and Chinese Journal of Food; and a guest editor of Food Chemistry: X (IF=6.1) and Frontiers in Immunology (IF=7.3).

Dr. Ma has published 54 articles in top-tier journals within the field, including Cell Metabolism, Seminars in Cancer Biology, Comprehensive Reviews in Food Science and Safety, Critical Reviews in Food Science and Nutrition, Analytica Chimica Acta, Food Chemistry, Food Hydrocolloids, etc. Among them, 32 papers were published with Dr. Ma as the first or corresponding author; the H-Index is 15; the cumulative impact factor is 378.4; the highest impact factor is 31.373; one paper was highly cited; two papers were selected as the journal cover page; two chapters were published in a handbook of Dietary Flavonoids and Plants and Phytomolecules for Immunomodulation, respectively (Springer Nature, 2022; Springer Nature, 2023). She applied for 16 Chinese patents, among which 3 patents has been authorized. She published a China Industry Standard (NY/T 3910-2021). She presided over 9 projects with the total funding over 5 million RMB, including the National Natural Science Foundation of China (32001716) and the National Key R&D Program of China (2023YFF1104002). She assisted organizing 4 ti

马灵君,1991年生,中国农业大学食品科学与营养工程学院副教授、博士生导师。2017年获美国加州大学戴维斯分校博士学位,师从Andrew Waterhouse教授。2018-2019年在耶鲁大学Richard Kibbey教授实验室从事博士后研究工作。2019年,她作为优秀人才、副教授应邀加盟中国农业大学。此后,她致力于食品中多酚氧化介导反应的研究,重点关注醌对色泽、风味、安全性、健康影响等方面的影响。马博士曾获中国科协青年精英科学家资助计划(2021年),是中国食品科技领域唯一获此殊荣的女科学家;她还曾获中国农业科技服务奖(2023年);国际医药与食品中植物化学物质研讨会(ISPMF,2023年)杰出服务奖;Wiley Open Science优秀作者奖(2021年);The David E. Gallo奖(2015年);美国酿酒与葡萄栽培学会最佳海报展示奖(2017年)。她是中国农业大学优秀人才(2019-至今);国际膳食营养与安全协会副秘书长(2021-至今);中国绿色食品发展专家(2021);国家果蔬加工工程技术研究中心委员(2019-至今);《食品前沿》(IF=9.9)、《e-Food》(IF=7.425)、《未来食品》杂志、《中国食品学报》青年编委;《Food Chemistry:马博士在《细胞代谢》、《癌症生物学研讨会》、《食品科学与安全综合评论》、《食品科学与营养关键评论》、《分析化学报》、《食品化学》、《食品亲水胶体》等领域顶级期刊上发表论文54篇。其中,以马博士为第一作者或通讯作者发表论文32篇,H-Index为15,累计影响因子378.4,最高影响因子31.373,高被引1篇,2篇论文入选期刊封面,2章分别发表在《Dietary Flavonoids and Plants and Phytomolecules for Immunomodulation》手册(Springer Nature,2022;Springer Nature,2023)。她申请了 16 项中国专利,其中 3 项已获授权。出版了中国行业标准(NY/T 3910-2021)。主持国家自然科学基金(32001716)、国家重点研发计划(2023YFF1104002)等项目9项,总经费超过500万元。她协助组织了 4 次 ISPMF(2020-2023 年)和 2 次中国果蔬大会(2022-2023 年)。在美国化学会(2017)、美国酿酒与葡萄栽培学会(2017)、ISPMF(2020-2023)等国际学术会议上做全会或主题报告16次。
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引用次数: 0
Unlocking the food treasures: Trachyspermum ammi–A comprehensive exploration from field to pharmacology 揭开食物宝藏的神秘面纱从田野到药理的全面探索
Pub Date : 2024-04-22 DOI: 10.1002/fsh3.12043
Fatima Siddiquie, Farogh Ahsan, Tarique Mahmood, Md. Afroz Ahmad, Aditya Singh, Shahzadi Bano

Recent pharmacological research on Tracyspermum ammi has unveiled its diverse medicinal properties, bolstering its status as a notable herbaceous plant. Cultivated extensively in regions like Egypt, Iran, Afghanistan, Pakistan, and India, T. ammi has drawn attention due to its rich essential oil content, prominently thymol. Commonly used in food processing, such as in pickles, this plant exhibits a wide array of pharmacological effects, from diuretic and antibacterial properties to potential as an antitussive, antiplatelet, antihypertensive, bronchodilator, and antihyperlipidemic agent. While the medicinal potential of T. ammi is acknowledged, challenges persist in optimizing its efficacy. The preclinical and clinical trials of T. ammi have been performed and data are compiled to assess its efficacy in humans. Novel drug delivery systems, including nanoparticles, microemulsions, niosomes, and liposomes, among others, offer a means to overcome the constraints associated with conventional formulations. In conclusion, the comprehensive overview presented here highlights the morphological characteristics, food processing, chemical constituents, pharmacological significance, preclinical and clinical trials along with traditional use and novel dosage forms of T. ammi which underscores the need for modernization in drug delivery systems to maximize its therapeutic potential thereby advancing the addition of herbal medicines into contemporary healthcare practices.

最近对百里香(Tracyspermum ammi)的药理学研究揭示了它的多种药用特性,巩固了它作为一种著名草本植物的地位。安米在埃及、伊朗、阿富汗、巴基斯坦和印度等地区广泛种植,因其富含精油(主要是百里酚)而备受关注。这种植物常用于食品加工,如腌制咸菜,具有广泛的药理作用,从利尿和抗菌特性到潜在的止咳、抗血小板、抗高血压、支气管扩张和降血脂作用。虽然安米蒿的药用潜力已得到认可,但在优化其药效方面仍存在挑战。目前已对天麻进行了临床前和临床试验,并汇编了数据以评估其对人体的疗效。新型给药系统,包括纳米颗粒、微乳剂、niosomes 和脂质体等,为克服与传统制剂相关的制约因素提供了一种方法。总之,本文的综合概述重点介绍了安米的形态特征、食品加工、化学成分、药理学意义、临床前和临床试验以及传统用法和新型剂型,强调了现代化给药系统的必要性,以最大限度地发挥其治疗潜力,从而推动将草药纳入当代医疗保健实践。
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引用次数: 0
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Food Safety and Health
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