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Hydrogel-based surface-enhanced Raman spectroscopy for food contaminant detection: A review on classification, strategies, and applications 基于水凝胶的表面增强拉曼光谱用于食品污染物检测:分类、策略和应用综述
Pub Date : 2023-07-19 DOI: 10.1002/fsh3.12010
Yuzhu Li, Shixuan Yang, Cheng Qu, Zhongxiang Ding, Honglin Liu

Toward the challenge on reliable determination of food contaminants to ensure food safety and security, surface-enhanced Raman spectroscopy (SERS) technology with single-molecule sensitivity through their “fingerprint” Raman signal has been developed into a fundamental and important molecular toolkit for food industry. Currently, hydrogel is attracting great interests in SERS sensing as a functional and flexible material. In this perspective, we first introduce the classification of common hydrogel and strategies for the synthesis of SERS substrates. Next, we highlight the response characteristics of hydrogel, including temperature response and pH response. Finally, we summarize the applications of hydrogel-based substrates for food contaminant detection and discuss its developing trends and challenges. Compared to traditional solid SERS substrates, hydrogel-based substrates have encouraging characteristics, such as unique flexibility to adhere to food surfaces for direct target molecule collection, and the stable three-dimensional network scaffold that prevents the aggregation of SERS hot spots, etc. These advantages suggest that hydrogel-based substrates have great potential for food safety analysis and monitoring.

为了应对可靠测定食品污染物以确保食品安全的挑战,通过其“指纹”拉曼信号具有单分子灵敏度的表面增强拉曼光谱(SERS)技术已发展成为食品工业的一个基础和重要的分子工具包。目前,水凝胶作为一种功能性和柔性材料,在SERS传感中引起了极大的兴趣。从这个角度来看,我们首先介绍了常见水凝胶的分类和SERS底物的合成策略。接下来,我们重点介绍水凝胶的响应特性,包括温度响应和pH响应。最后,我们总结了水凝胶基质在食品污染物检测中的应用,并讨论了其发展趋势和挑战。与传统的固体SERS基质相比,基于水凝胶的基质具有令人鼓舞的特性,如粘附在食物表面用于直接靶分子收集的独特灵活性,以及防止SERS热点聚集的稳定三维网络支架等。这些优势表明,基于水凝胶的基质在食品安全分析和监测方面具有巨大潜力。
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引用次数: 0
Novel analytical method detects genotoxic compounds in edible oils 一种检测食用油中遗传毒性化合物的新分析方法
Pub Date : 2023-07-19 DOI: 10.1002/fsh3.12016
Danyue Zhao

Edible oils rich in unsaturated fatty acids are essential components of a healthy diet. However, food safety problems existing in these seemingly healthy oils can be overlooked. Recently, a new study by Prof. Gertrud Morlock, Chair of Food Sciences at Justus Liebig University Giessen and her Ph.D. student, Daniel Meyer, found that healthy oils recommended for daily consumption may contain a considerable amount of genotoxic compounds hazardous to human health. The study, published in the journal Food Chemistry, also demonstrates the application of newly developed non-target planar genotoxicity profiling method for detecting genotoxic compounds in edible oils.

Genotoxic compounds are substances that can induce DNA damage and are potential carcinogens. They are widely present in a variety of sources, including food, air, and water. While some well-known genotoxic compounds are easily detected and regulated, others may be overlooked due to the selective nature or lack of sensitivity of current analytical techniques. The researchers hypothesized that some less studied genotoxic compounds are present in healthy food materials that escape detection and exist as a source of hazards in the household products. Thus, the development of a more sensitive and untargeted bio-analytical method is much needed. To this end, they sampled 33 oil samples including 31 healthy oils from local households and studied them under different household storage conditions. Analysis using a planar genotoxicity bioassay that combines separation with effect detection on the same surface allows sensitive detection of genotoxins in the oils. This bioassay employs high-performance thin-layer chromatography coupled with a genetically modified Salmonella typhimurium strain equipped with the SOS-Umu-C repair mechanism. The genotoxic compound zones were then characterized by high-resolution mass spectrometry.

The study revealed that genotoxic substances, such as epoxides and hydroperoxides produced due to the oxidation of unsaturated fatty acids, were detected in multiple oil samples. Moreover, the amount of genotoxic compounds in the oils increased with prolonged storage and air exposure. This is the first method capable of detecting genotoxic compounds in edible oils, in a generic and sensitive manner.

Overall, the study has important implications for public health and food safety. It provides a potential solution to the problem of detecting a spectrum of genotoxic compounds in foods and other sources. It also highlights the need for more sensitive and accurate analytical techniques that can cover a wide range of toxic compounds in food analysis. On top of this, the study underscores the importance of continued research into the sources of genotoxicity in food, feed, dietary supplements, and cosmetics.

In the future, more studies are needed to redefine good manufacturing practices, safe product formulations, and proper storage conditions to ensure the

富含不饱和脂肪酸的食用油是健康饮食的重要组成部分。然而,这些看似健康的油脂中存在的食品安全问题却被忽视了。最近,吉森Justus Liebig大学食品科学系主任Gertrud Morlock教授和她的博士生Daniel Meyer的一项新研究发现,推荐日常食用的健康油脂可能含有大量危害人类健康的基因毒性化合物。这项发表在《食品化学》杂志上的研究还展示了新开发的非靶标平面遗传毒性分析方法在检测食用油中遗传毒性化合物方面的应用。基因毒性化合物是可引起DNA损伤的物质,是潜在的致癌物。它们广泛存在于各种来源中,包括食物、空气和水。虽然一些众所周知的基因毒性化合物很容易被检测和调节,但由于当前分析技术的选择性或缺乏敏感性,其他化合物可能会被忽视。研究人员假设,一些研究较少的基因毒性化合物存在于健康食品材料中,这些材料逃脱了检测,并作为家用产品中的危险源存在。因此,迫切需要开发一种更灵敏、无针对性的生物分析方法。为此,他们从当地家庭抽取了33份油样,其中包括31份健康油,并在不同的家庭储存条件下进行了研究。使用平面遗传毒性生物测定法进行分析,该法结合了在同一表面上的分离和效果检测,可以灵敏地检测油中的遗传毒素。该生物测定采用高效薄层色谱法与配备有SOS-Umu-C修复机制的转基因鼠伤寒沙门氏菌菌株相结合。然后通过高分辨率质谱法对基因毒性化合物区域进行表征。研究表明,在多个石油样本中检测到遗传毒性物质,如不饱和脂肪酸氧化产生的环氧化物和氢过氧化物。此外,油中基因毒性化合物的含量随着储存时间的延长和暴露在空气中而增加。这是第一种能够以通用和敏感的方式检测食用油中基因毒性化合物的方法。总的来说,这项研究对公众健康和食品安全具有重要意义。它为检测食品和其他来源中的一系列基因毒性化合物提供了一个潜在的解决方案。它还强调了对更灵敏和准确的分析技术的需求,这些技术可以涵盖食品分析中的各种有毒化合物。除此之外,这项研究强调了继续研究食品、饲料、膳食补充剂和化妆品中遗传毒性来源的重要性。未来,还需要更多的研究来重新定义良好的生产实践、安全的产品配方和适当的储存条件,以确保富含油脂的食品、饲料、膳食补充剂和化妆品在推荐的产品保质期内的稳定性。此外,作者建议,类似的非靶点筛选可用于进一步分析复杂样品中具有神经毒性、细胞毒性、抗菌性和内分泌作用的化合物。最后,作者主张,可以将分析范式转向基于非目标平面图像的遗传毒性筛查,用于复杂家庭样本的常规分析,以确保消费者安全。
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引用次数: 0
Tackling the safety and health effects of food colorants 处理食品着色剂的安全和健康影响
Pub Date : 2023-07-19 DOI: 10.1002/fsh3.12015
Valeria Weiss, Zoya Okun, Avi Shpigelman

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引用次数: 0
Novel technologies for improving quality of tofu products and their packaging: A critical overview 提高豆腐产品及其包装质量的新技术:综述
Pub Date : 2023-07-19 DOI: 10.1002/fsh3.12007
Jie Du, Min Zhang, Liqing Qiu, Arun S. Mujumdar, Yamei Ma

There are many kinds of tofu products, and they are mainly found in Asia. This paper mainly summarizes and classifies the tofu products of different countries through the analysis of the characteristics of different products and the differences between them. The storage conditions for most bean products are typically harsh, resulting in the shelf life of some fresh beans limited to 3–5 days. The new packaging technology avoids the shortcomings of traditional packaging, which makes it more effective to store. In this paper, biodegradable packaging materials, nanomaterials, active packaging, and intelligent packaging were reviewed. The significance of this review is to introduce various types of tofu products to gain a more comprehensive understanding of their advantages and disadvantages and to apply different packaging techniques to improve the preservation environment of tofu products. The purpose is to find suitable packaging technology, materials, and development route of tofu products.

豆腐制品种类繁多,主要分布在亚洲。本文主要通过分析不同国家豆腐产品的特点及其差异,对不同国家的豆腐产品进行总结和分类。大多数豆制品的储存条件通常很苛刻,导致一些新鲜豆的保质期限制在3-5天。新的包装技术避免了传统包装的缺点,使其更有效地储存。本文综述了生物降解包装材料、纳米材料、活性包装和智能包装。本综述的意义在于介绍各种类型的豆腐产品,以更全面地了解它们的优缺点,并应用不同的包装技术来改善豆腐产品的保存环境。目的是寻找合适的豆腐产品包装技术、材料和开发路线。
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引用次数: 0
Exploring the impacts of novel cold plasma technology on the volatile profile, flavor, and aroma properties of fruits and vegetables—A review 探索新型冷等离子体技术对果蔬挥发性、风味和香气特性的影响——综述
Pub Date : 2023-07-19 DOI: 10.1002/fsh3.12008
Doaa Abouelenein, Giovanni Caprioli, Ahmed M. Mustafa

Cold plasma is a novel nonthermal technology that has recently numerous applications in the food industry. It destroys microorganisms, preserves food, and maintains quality without employing chemical antimicrobial agents. However, food processing by cold plasma (CP) can be associated with food quality challenges, so research on the applications of this technology and its effects on food quality are increasing. This paper reviews the effect of CP on the volatile profile, flavor, and aroma properties of fruits and vegetables. CP induces some chemical modifications in volatile compounds, and these changes vary with the CP operating conditions such as voltage, frequency, and treatment duration parameters and subsequently induces changes in the aroma and flavor of foods. The operating conditions may be properly controlled to avoid any unfavorable effects and provide more accepted food by focusing on the development of favorable flavor and aroma characteristics and reducing the incidence of undesirable ones. Also, more sophisticated techniques for sensory evaluation of processed foods should be developed and commercialized to get standardized outcomes. In conclusion, the data presented in this work highlight the possibility of flavor and aroma modifications and improvement of sensory quality in food products by using CP technology.

冷等离子体是一种新型的非热技术,最近在食品工业中有许多应用。它可以在不使用化学抗菌剂的情况下破坏微生物、保存食物并保持质量。然而,冷等离子体(CP)食品加工可能与食品质量挑战有关,因此对该技术的应用及其对食品质量的影响的研究正在增加。本文综述了CP对水果和蔬菜的挥发性、风味和香气特性的影响。CP引起挥发性化合物的一些化学修饰,这些变化随着CP操作条件(如电压、频率和处理持续时间参数)的变化而变化,随后引起食物香气和风味的变化。可以适当控制操作条件,以避免任何不利影响,并通过关注有利风味和香气特征的发展和减少不期望的风味和香气特性的发生来提供更可接受的食物。此外,应该开发和商业化更复杂的加工食品感官评估技术,以获得标准化的结果。总之,这项工作中提供的数据突出了利用CP技术改变食品风味和香气以及改善感官质量的可能性。
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引用次数: 0
Cell-based food needs collaborative efforts for safe production and suitable consumption 基于细胞的食品需要合作,以确保安全生产和适当消费
Pub Date : 2023-07-15 DOI: 10.1002/fsh3.12009
Muhammad Waseem, Yaqoob Majeed

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引用次数: 1
Advancements in precision nutrition: Steady-state targeted delivery of food functional factors for nutrition intervention of chronic diseases 精准营养的进展:用于慢性病营养干预的食物功能因子的稳态靶向递送
Pub Date : 2023-07-11 DOI: 10.1002/fsh3.12006
Xiaoting Yu, A. M. Abd El-Aty, Wentao Su, Mingqian Tan

Nutritional intervention plays a significant role in controlling the progression of chronic diseases and improving therapeutic outcomes. Food functional factors are bioactive compounds found in foods that can regulate body's physiological functions and support health by regulating enzyme activity and metabolic pathways. However, many food functional factors face significant challenges in terms of their bioavailability, stability, and solubility. Furthermore, individual differences in genetics, metabolism, lifestyle, and environmental factors can significantly influence nutrient requirements and intake. Therefore, personalized nutritional intervention and precise delivery based on individual characteristics are necessary to achieve precision nutrition. Steady-state targeted delivery systems have emerged as a promising approach to improving the precise nutritional interventions for chronic diseases. In this review, we explore the latest progress in the steady-state targeted delivery of food functional components for precision nutrition. We discuss the challenges and opportunities associated with these systems as well as their potential applications in managing chronic diseases and improving health outcomes. The review highlights the significant role that steady-state targeted delivery systems can play in advancing precision nutrition and thus promoting better health for individuals.

营养干预在控制慢性病进展和改善治疗效果方面发挥着重要作用。食物功能因子是在食物中发现的生物活性化合物,可以通过调节酶活性和代谢途径来调节身体的生理功能并支持健康。然而,许多食品功能因子在生物利用度、稳定性和溶解度方面面临着重大挑战。此外,遗传、代谢、生活方式和环境因素的个体差异会显著影响营养需求和摄入量。因此,个性化的营养干预和基于个体特征的精准投放是实现精准营养的必要条件。稳态靶向给药系统已成为改善慢性病精确营养干预的一种很有前途的方法。在这篇综述中,我们探讨了用于精确营养的食品功能成分稳态靶向递送的最新进展。我们讨论了与这些系统相关的挑战和机遇,以及它们在管理慢性病和改善健康结果方面的潜在应用。该综述强调了稳态靶向给药系统在推进精准营养从而促进个人更好健康方面可以发挥的重要作用。
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引用次数: 4
Determination of seroprevalence and associated factors of Helicobacter pylori infection among Bangladeshi and Somalian students residing in Dhaka city. 居住在达卡市的孟加拉国和索马里学生幽门螺杆菌感染血清阳性率及相关因素的测定
Pub Date : 2021-01-01 DOI: 10.5455/fsh.2021.27
Rabneya Ferdous, B. Mohamud, S. M. Asna, Mohammad Mushfequr Rahman
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引用次数: 0
Knowledge, attitude and practices (KAP) towards COVID-19 and assessment of risks of infection (RI) by SARS-CoV-2 among the Bangladeshi population: An online cross sectional survey 孟加拉国人口对COVID-19的知识、态度和做法(KAP)以及SARS-CoV-2感染风险评估:一项在线横断面调查
Pub Date : 2020-04-28 DOI: 10.21203/rs.3.rs-24562/v1
Tasnima Haque, K. Hossain, M. R. Bhuiyan, S. Ananna, Md. Anower Hussain, M. Islam, Asif Ahmed, M. M. Rahman
The COVID19 pandemic has been transmitted worldwide rapidly. The best ways of preventing this virus are to know about and act accordingly. An online cross sectional survey was conducted to know the knowledge, attitude and practices towards COVID19 and to assess the risks of infections among Bangladeshi population. Among 2045 respondents, 54·87% respondents kept good knowledge. Knowledge was significantly diverged across age, gender, education levels, residences, income groups, and marital status. Despite the knowledge, the attitude and practices of Bangladeshi people are not impressive. Among population, 32·08%, and 44·30% people were in high, and in medium risk of infection respectively. Everybody is in risk. Reasons for the mediocre attitude and practices could be the poor knowledge, nonscientific and orthodox religious believe. Government and policy makers must consider these knowledge levels, attitude & practices and the risk of infection assessment to implement productive interventions for preventing the COVID19.
2019冠状病毒病大流行在全球范围内迅速传播。预防这种病毒的最佳方法是了解并采取相应的行动。开展了一项在线横断面调查,以了解孟加拉国人口对covid - 19的知识、态度和做法,并评估其感染风险。在2045名受访者中,54.87%的受访者保持良好的知识。知识在年龄、性别、教育程度、居住地、收入群体和婚姻状况之间存在显著差异。尽管知道这些,但孟加拉国人的态度和做法并不令人印象深刻。高危人群占32.08%,中危人群占44.30%。每个人都有风险。这种平庸的态度和行为的原因可能是知识贫乏,不科学和正统的宗教信仰。政府和决策者必须考虑这些知识水平、态度和做法以及感染风险评估,以实施有效的干预措施,预防covid - 19。
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引用次数: 81
Impact of control strategies on COVID-19 pandemic and the SIR model based forecasting in Bangladesh. 控制策略对COVID-19大流行的影响以及孟加拉国基于SIR模型的预测。
Pub Date : 2020-04-23 DOI: 10.1101/2020.04.19.20071415
M. M. Rahman, Asif Ahmed, K. Hossain, Tasnima Haque, Md. Anwar Hossain
COVID-19 is transmitting worldwide drastically and infected nearly two and half million of people sofar. Till date 2144 cases of COVID-19 is confirmed in Bangladesh till 18th April though the stage-3/4 transmission is not validated yet. To project the final infection numbers in Bangladesh we used the SIR mathematical model. We also tried to demonstrate the impact of control strategies like social distancing on the COVID-19 transmission. Due to large population and socio-economic characteristics, we assumed 60% social distancing and lockdown can be possible. Assuming that, the predicated final size of infections will be 3782558 on the 92th day from the first infections. To estimate the impact of social distancing we assumed eight different scenarios, the predicted results confirmed the positive impact of this type of control strategies suggesting that by strict social distancing and lockdown, COVID-19 infection can be under control and then the infection cases will steadily decrease down to zero.
COVID-19正在全球范围内迅速传播,迄今已感染近250万人。截至4月18日,孟加拉国已确诊2144例COVID-19病例,但尚未证实3/4阶段传播。为了预测孟加拉国的最终感染人数,我们使用了SIR数学模型。我们还试图证明社交距离等控制策略对COVID-19传播的影响。由于人口众多和社会经济特点,我们假设60%的社交距离和封锁是可能的。假设,在第一次感染后的第92天,预测的最终感染规模为3782558。为了估计保持社交距离的影响,我们假设了8种不同的情景,预测结果证实了这种控制策略的积极影响,表明通过严格的社交距离和封锁,COVID-19感染可以得到控制,然后感染病例将稳步减少到零。
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引用次数: 15
期刊
Food Safety and Health
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