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Biocomputation: comparing genomes 生物计算:比较基因组
Pub Date : 2002-01-01 DOI: 10.1109/5992.976436
B. Mishra
The theory behind biocomputing is to look to biological structures and processes for new ways of solving difficult computational problems. But this need not be a one-way street: advances in computing can feed back into the study of biology, leading to better biotechnological tools.
生物计算背后的理论是寻找生物结构和过程的新方法来解决困难的计算问题。但这并不一定是一条单行道:计算的进步可以反馈到生物学的研究中,从而产生更好的生物技术工具。
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引用次数: 5
From the editors: what's new 来自编辑:有什么新消息
Pub Date : 2002-01-01 DOI: 10.1109/MCSE.2002.10000
F. Sullivan
Many of the startling results obtained in the 20th century about the foundations of physics actually appear in papers produced years before the official discovery. One nice example is the existence of antimatter, which was predicted from symmetries in Dirac's mathematical treatment of quantum field theory and later observed experimentally. However, according to at least some experts, one of Einstein's earliest attempts at a unified field theory actually predicted antimatter as a side effect. Einstein discarded the result, perhaps because he abandoned that attempt as he did all other attempts except the one he was working on a the time of his death.
许多在20世纪获得的关于物理学基础的惊人结果,实际上早在正式发现之前几年就已经出现在论文中了。一个很好的例子是反物质的存在,这是狄拉克在量子场论的数学处理中从对称性中预测出来的,后来通过实验观察到了。然而,至少根据一些专家的说法,爱因斯坦对统一场论的最早尝试之一实际上预测了反物质是一种副作用。爱因斯坦放弃了这个结果,也许是因为他在去世前放弃了这个尝试,就像他放弃了所有其他的尝试一样,除了他正在研究的那个。
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引用次数: 0
Willing Suspension of Disbelief 自愿停止怀疑
Pub Date : 2001-11-01 DOI: 10.1109/MCSE.2001.10011
F. Sullivan
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引用次数: 8
Elementary celestial mechanics using Matlab 基础天体力学Matlab
Pub Date : 2001-11-01 DOI: 10.1109/5992.963427
E. Onori
The Trojan asteroids, discovered almost a century ago, are direct evidence for stability in the pure three-body problem. Two groups of asteroids share Jupiter's orbit, preceding or trailing it by an angle of 60 degrees. Because the Sun and Jupiter are by far the heaviest bodies, the restricted three body model is perfectly adequate to describe the relevant dynamics, and the perturbations due to the attraction of other planets do not significantly modify the orbit. For a hypothetical Lagrangian satellite bound to Earth and the Moon, we cannot discard the Sun's influence a priori. The problem of stability in this case is very hard; no analytic result is known, up to now. However, numerical analysis can give us a plausible answer. In spring 1999, I made this problem a classroom activity for my physics undergraduate students at the University of Parma. These students had an elementary background in classical mechanics but no computational-physics training. The choice of Matlab as a working environment was rather natural. With a little sacrifice in speed compared to Fortran or C, Matlab let us build a working program in a few days, including visualization and a friendly user interface. We easily found clear numerical evidence that the equilateral orbits L/sub 4/ and L/sub 5/ in the Earth-Moon system are unstable. I describe the program's setup, its Matlab implementation and the results.
近一个世纪前发现的特洛伊小行星是纯三体问题稳定性的直接证据。两组小行星共享木星的轨道,在木星之前或之后以60度的角度运行。由于太阳和木星是迄今为止最重的天体,因此限制三体模型完全足以描述相关动力学,并且由于其他行星的吸引力而引起的扰动不会显著改变轨道。对于一个与地球和月球相连的假想拉格朗日卫星,我们不能先验地抛弃太阳的影响。在这种情况下稳定性的问题是非常困难的;到目前为止,还没有已知的分析结果。然而,数值分析可以给我们一个合理的答案。1999年春天,我把这个问题作为帕尔马大学物理系本科生的课堂活动。这些学生有基本的经典力学背景,但没有受过计算物理训练。选择Matlab作为工作环境是很自然的。与Fortran或C相比,Matlab在速度上做了一点牺牲,让我们在几天内构建一个工作程序,包括可视化和友好的用户界面。我们很容易找到明确的数值证据,证明地月系统的等边轨道L/sub 4/和L/sub 5/是不稳定的。我描述了程序的设置,它的Matlab实现和结果。
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引用次数: 1
Threads and Surprises 线索和惊喜
Pub Date : 2001-07-01 DOI: 10.1109/MCSE.2001.10008
Francis Sullivan
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引用次数: 0
Onward and Upward 向前和向上
Pub Date : 2001-06-19 DOI: 10.1109/MCSE.2001.10006
F. Sullivan
This issue of CISE contains several articles on the general topic of “Computational Challenges for the 21st Century.” We plan to have a number of articles and essays on this subject throughout the year. In part, we’re building on the themes set in last year’s list of the “Top 10 Algorithms,” but we’re attempting to address some broader issues too. Some of the more scientific of these include identifying the barriers to achieving even more results through computation and examining whether we’re missing any new opportunities or ideas offered by computation. We also want to look at some social and economic issues, such as how US government policies related to computation will continue to evolve and if high‐speed communication and computation offer pure benefits with no drawbacks?
本期CISE包含了几篇关于“21世纪计算挑战”的文章。我们计划全年发表一些关于这个主题的文章和论文。在某种程度上,我们正在建立在去年“十大算法”列表中设定的主题上,但我们也在试图解决一些更广泛的问题。其中一些更科学的方法包括识别通过计算获得更多结果的障碍,以及检查我们是否错过了计算提供的任何新机会或想法。我们也想看看一些社会和经济问题,比如美国政府与计算相关的政策将如何继续发展,高速通信和计算是否提供了纯粹的好处而没有缺点?
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引用次数: 0
Guest Editors’ Introduction: Tomorrow’s Hardest Problems 客座编辑介绍:明天最难的问题
Pub Date : 2001-06-19 DOI: 10.1109/MCSE.2001.10007
G. Cybenko, F. Sullivan
In 1900, David Hilbert presented 23 problems at the International Congress of Mathematicians held in Paris. Hilbert’s problems spanned the spectrum from rather trivial (Problem 3 on the equality of the volumes of two tetrahedra) to the probably impossible (Problem 6 on the axiomatization of physics). Nonetheless, they challenged many of the leading scientists and mathematicians of the 20th century and set the tone for mathematical research, especially in the early part of the century.
1900年,大卫·希尔伯特在巴黎举行的国际数学家大会上提出了23个问题。希尔伯特的问题涵盖了从相当琐碎的问题(问题3关于两个四面体的体积相等)到可能不可能的问题(问题6关于物理的公理化)。尽管如此,他们挑战了20世纪许多顶尖的科学家和数学家,并为数学研究奠定了基调,特别是在20世纪初。
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引用次数: 1
The Crucial 0.1 Percent Difference 关键的0.1%的差别
Pub Date : 2001-06-19 DOI: 10.1109/MCSE.2001.10005
N. Smith
Human beings, equipped with more genes than lesser creatures, are consequently smarter than other beasts. Right? Wrong. A frantic competition between two philosophies for deciphering the entire human genome has, in one of its important accomplishments, deflated this long‐standing presumption. Both competitors agree on an estimate that humans have about 30,000 genes, which is roughly the same as a mouse’s inventory of genes and well below earlier estimates of as much as 100,000 human genes. Furthermore, humans possess only 300 genes not found in mice.
人类比低等生物拥有更多的基因,因此比其他动物更聪明。对吧?错了。破译整个人类基因组的两种哲学之间的疯狂竞争,在其重要成就之一中,粉碎了这种长期存在的假设。两家竞争对手都认为人类大约有3万个基因,这与老鼠的基因数量大致相同,远低于此前估计的10万个基因。此外,人类只有300个老鼠没有的基因。
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引用次数: 0
Scientific programming in field theory, part 1 场理论中的科学规划,第1部分
Pub Date : 2001-05-01 DOI: 10.5555/377269.377287
HannemannRegina, HannemannJens, ZellerhoffMichael, KlinkenbuschLudger
Today, field-theory scientists tackle most contemporary research problems numerically, not analytically. For this purpose, the field-theory community has developed, combined, and described numerous...
今天,场论科学家用数值方法解决大多数当代研究问题,而不是用分析方法。为此目的,场论团体已经发展、结合并描述了许多…
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引用次数: 2
Do the Math 计算一下
Pub Date : 2001-03-01 DOI: 10.1109/MCSE.2001.10002
F. Sullivan
Relativity and quantum theory, the two dramatic advances in physics of the 20th century, are subtle, highly counterintuitive, and mathematical in a fundamental way. In fact, relativity and quantum theory can force one to rethink one's view of the nature of physical reality and ask questions such as "What does 'simultaneous' mean?" "Can one know the precise coordinates of a physical object?" and even "Is that cat alive or dead?" These are good questions which are well worth asking and which might lead to deeper understanding. On the other hand, asking the questions blindly can result in confusion and fuzzy pictures of what's actually happening. The confusion can be entertaining and might even result in popularizations with great titles, such as "Entering the quantum world of self-realization by way of the hidden door" or "Relativity: the story of mass and how to control it (a weight-management method for the postmodern epoch!)" But there's a downside, too.
相对论和量子论是20世纪物理学的两大重大进步,它们非常微妙,非常违反直觉,从根本上讲是数学的。事实上,相对论和量子理论可以迫使人们重新思考自己对物理现实本质的看法,并提出诸如“‘同时’是什么意思?”"人能知道物体的精确坐标吗"甚至"那只猫是死是活"这些都是很值得问的好问题,可能会导致更深层次的理解。另一方面,盲目地问问题可能会导致混乱和对实际发生的事情的模糊印象。这种困惑可以很有趣,甚至可能会带来一些很好的标题,比如“通过隐藏的门进入自我实现的量子世界”或“相对论:质量的故事以及如何控制它(后现代时代的体重管理方法!)”。但这也有不利的一面。
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引用次数: 0
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