Pub Date : 2019-06-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.06.006
Yan-qin Chen, Peng Peng, B. Hou
Objective To evaluate the curative effect and prognosis of endoscopic papillary large balloon dilatation (EPLBD) in the treatment of choledocholithiasis. Methods A total of 153 patients with choledocholithiasis (>1.0 cm in stone diameter) admitted and treated in Shanxi People′s Hospital from August 2016 to November 2017 were randomly divided into two groups according to the random number table: the EPLBD group (n=83) and the small endoscopic sphincterotomy plus large balloon dilatation (ESLBD) group (n=70) . The success rate of stone removal, the rate of lithotripsy, and the incidence of short-term and long-term complications were compared between the two groups. Results There were no statistical differences between the EPLBD group and the ESLBD group in total stone removal rate [95.2% (79/83) VS 97.1% (68/70) , χ2=0.388, P=0.533] and one-time stone removal rate [92.8% (77/83) VS 90.0% (63/70) , χ2=0.375, P=0.540]. The lithotripsy rate between the two groups had no statistical difference [25.3% (21/83) VS 35.7% (25/70) , χ2=1.958, P=0.162]. There was no statistical difference in the incidence of recent complications between the two groups [43.4% (36/83) VS 40.0% (28/70) , χ2=0.178, P=0.673]. No postoperative perforation was found in either group. The follow-up time was 22.7±4.3 months in the EPLBD group, and 20.8±6.3 months in the ESLBD group.The cumulative recurrent rate of choledocholithiasis in the two groups were 2.4% (2/83) and 15.7% (11/70) , respectively, and the difference was significant (P=0.003) . Conclusion Simple EPLBD in the treatment of choledocholithiasis is equivalent to ESLBD in the success rate of stone removal, utilization rate of lithotripsy, and incidence of recent complications, but the long-term stone recurrence rate of EPLBD is lower than that of ESLBD. EPLBD is effective and safe on the treatment of choledocholithiasis. Key words: Choledocholithiasis; Cholangiopancreatography, endoscopic retrograde; Endoscopic papillary large balloon dilatation; Small endoscopic sphincterotomy plus large balloon dilatation
{"title":"Curative effects and prognosis of endoscopic papillary large balloon dilatation on the treatment of choledocholithiasis","authors":"Yan-qin Chen, Peng Peng, B. Hou","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.06.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.06.006","url":null,"abstract":"Objective \u0000To evaluate the curative effect and prognosis of endoscopic papillary large balloon dilatation (EPLBD) in the treatment of choledocholithiasis. \u0000 \u0000 \u0000Methods \u0000A total of 153 patients with choledocholithiasis (>1.0 cm in stone diameter) admitted and treated in Shanxi People′s Hospital from August 2016 to November 2017 were randomly divided into two groups according to the random number table: the EPLBD group (n=83) and the small endoscopic sphincterotomy plus large balloon dilatation (ESLBD) group (n=70) . The success rate of stone removal, the rate of lithotripsy, and the incidence of short-term and long-term complications were compared between the two groups. \u0000 \u0000 \u0000Results \u0000There were no statistical differences between the EPLBD group and the ESLBD group in total stone removal rate [95.2% (79/83) VS 97.1% (68/70) , χ2=0.388, P=0.533] and one-time stone removal rate [92.8% (77/83) VS 90.0% (63/70) , χ2=0.375, P=0.540]. The lithotripsy rate between the two groups had no statistical difference [25.3% (21/83) VS 35.7% (25/70) , χ2=1.958, P=0.162]. There was no statistical difference in the incidence of recent complications between the two groups [43.4% (36/83) VS 40.0% (28/70) , χ2=0.178, P=0.673]. No postoperative perforation was found in either group. The follow-up time was 22.7±4.3 months in the EPLBD group, and 20.8±6.3 months in the ESLBD group.The cumulative recurrent rate of choledocholithiasis in the two groups were 2.4% (2/83) and 15.7% (11/70) , respectively, and the difference was significant (P=0.003) . \u0000 \u0000 \u0000Conclusion \u0000Simple EPLBD in the treatment of choledocholithiasis is equivalent to ESLBD in the success rate of stone removal, utilization rate of lithotripsy, and incidence of recent complications, but the long-term stone recurrence rate of EPLBD is lower than that of ESLBD. EPLBD is effective and safe on the treatment of choledocholithiasis. \u0000 \u0000 \u0000Key words: \u0000Choledocholithiasis; Cholangiopancreatography, endoscopic retrograde; Endoscopic papillary large balloon dilatation; Small endoscopic sphincterotomy plus large balloon dilatation","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"411-415"},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45519728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.06.008
Tian Yu, Shuodong Wu
Objective To study the relationship between juxtapapillary duodenal diverticulum (JPDD) and pancreaticobiliary diseases, and the effect of JPDD on the diagnosis and treatment of ERCP. Methods A retrospective analysis was performed on data of 1 230 patients who had received ERCP in general surgery departments of Shengjing Hospital of China Medical University from January 2012 to January 2017. The patients were divided into JPDD group (n=360) and non-JPDD group (n=870) according to whether JPDD was found. Patients with JPDD were divided into intradiverticular papilla group (n=41) and non-intradiverticular papilla group (n=319) according to whether the papilla located in diverticulum. The incidence of pancreaticobiliary diseases, success rate of cannulation, success rate of stones removal, and incidence of postoperative complications among each group were compared by using chi-square test or Fisher′s exact probability. P<0.05 was statistically significant. Results The incidence of choledocholithiasis, primary choledocholithiasis and recurrent choledocholithiasis were 87.78% (316/360) , 31.11% (112/360) , and 6.67% (24/360) , respectively, in the JPDD group, and 75.52% (657/870) , 19.08% (166/870) , and 4.02% (35/870) , respectively, in the non-JPDD group. There were significant differences between the two groups (χ2=23.158, P 0.05) . The incidence of recurrent choledocholithiasis in the intradiverticular papilla group and the non-intradiverticular papilla group were 14.63% (6/41) and 5.64% (18/319) , respectively, with significant difference (χ2=4.721, P=0.030) . There were no significant differences between the two groups in the incidence of choledocholithiasis and primary choledocholithiasis, the success rate of cannulation and complete stones removal during the first ERCP session, as well as the incidence of postoperative hemorrhage, pancreatitis and hyperamylasemia (all P>0.05) . Conclusion JPDD is associated with the occurrence of primary choledocholithiasis. JPDD patients, especially the patients with intradiverticular papilla, are more likely to have recurrent choledocholithiasis after ERCP treatment. Key words: Cholangiopancreatography, endoscopic retrograde; Juxtapapillary duodenal diverticulum; Intradiverticular papilla
{"title":"Association of juxtapapillary duodenal diverticulum with pancreaticobiliary diseases and with diagnosis and treatment of endoscopy","authors":"Tian Yu, Shuodong Wu","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.06.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.06.008","url":null,"abstract":"Objective \u0000To study the relationship between juxtapapillary duodenal diverticulum (JPDD) and pancreaticobiliary diseases, and the effect of JPDD on the diagnosis and treatment of ERCP. \u0000 \u0000 \u0000Methods \u0000A retrospective analysis was performed on data of 1 230 patients who had received ERCP in general surgery departments of Shengjing Hospital of China Medical University from January 2012 to January 2017. The patients were divided into JPDD group (n=360) and non-JPDD group (n=870) according to whether JPDD was found. Patients with JPDD were divided into intradiverticular papilla group (n=41) and non-intradiverticular papilla group (n=319) according to whether the papilla located in diverticulum. The incidence of pancreaticobiliary diseases, success rate of cannulation, success rate of stones removal, and incidence of postoperative complications among each group were compared by using chi-square test or Fisher′s exact probability. P<0.05 was statistically significant. \u0000 \u0000 \u0000Results \u0000The incidence of choledocholithiasis, primary choledocholithiasis and recurrent choledocholithiasis were 87.78% (316/360) , 31.11% (112/360) , and 6.67% (24/360) , respectively, in the JPDD group, and 75.52% (657/870) , 19.08% (166/870) , and 4.02% (35/870) , respectively, in the non-JPDD group. There were significant differences between the two groups (χ2=23.158, P 0.05) . The incidence of recurrent choledocholithiasis in the intradiverticular papilla group and the non-intradiverticular papilla group were 14.63% (6/41) and 5.64% (18/319) , respectively, with significant difference (χ2=4.721, P=0.030) . There were no significant differences between the two groups in the incidence of choledocholithiasis and primary choledocholithiasis, the success rate of cannulation and complete stones removal during the first ERCP session, as well as the incidence of postoperative hemorrhage, pancreatitis and hyperamylasemia (all P>0.05) . \u0000 \u0000 \u0000Conclusion \u0000JPDD is associated with the occurrence of primary choledocholithiasis. JPDD patients, especially the patients with intradiverticular papilla, are more likely to have recurrent choledocholithiasis after ERCP treatment. \u0000 \u0000 \u0000Key words: \u0000Cholangiopancreatography, endoscopic retrograde; Juxtapapillary duodenal diverticulum; Intradiverticular papilla","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"422-426"},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49600559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.06.005
Bo Liu, Wei Wang, Xin-Gang Shi, Zhendong Jin, Zhao-Shen Li
Objective To evaluate the clinical value of endoscopic retrograde pancreatic drainage (ERPD) in patients with pancreatic fistula. Methods Data of 42 patients with pancreatic fistula, who were treated with ERPD at Changhai Hospital and Henan Provincial People's Hospital from June 2013 to September 2018, were collected. The pancreatic fistula curative rate, healing duration of pancreatic fistula, and the incidence of complications were analyzed. Results Among 42 patients with pancreatic fistula, there were 30 males (71.4%) and 12 females (28.6%) with mean age of 41.5±12.8 years old. Pancreatic duct stents of 37 cases (88.1%) went across the fistula. The overall curative rate was 90.5% (38/42) . The median healing duration of pancreatic fistula was 32.0 d (8-183 d) . The healing time of pancreatic fistula after injury (19.0±9.9 d, t=3.50, P=0.002) and of pancreatic fistula after surgery (20.3±10.7 d, t=3.35, P=0.003) were shorter than that of pancreatic fistula after acute severe pancreatitis (60.0±48.6 d) . The healing time of pancreatic fistula with pancreatic pseudocysts was longer than that of pancreatic fistula without pancreatic pseudocysts (65.3±55.4 d VS 32.6±23.6 d, t=2.21, P=0.040) . There were no significant differences in pancreatic fistula curative rate, pancreatic healing duration and times of ERCP in pancreatic fistula at different position.Postoperative stent-related complications occurred in 2 patients (4.8%) , and 1 patient (2.4%) developed mild pancreatitis. Conclusion ERPD is an important treating method with good therapeutic effect and low complications for pancreatic fistula. Key words: Stent; Pancreatic fistula; Endoscopic retrograde pancreatic drainage
目的探讨内镜下逆行胰管引流术(ERPD)治疗胰瘘的临床价值。方法收集2013年6月至2018年9月在长海医院和河南省人民医院行ERPD治疗的42例胰瘘患者的资料。分析胰瘘治愈率、胰瘘愈合时间及并发症发生率。结果42例胰瘘患者中，男性30例(71.4%)，女性12例(28.6%)，平均年龄41.5±12.8岁。经胰瘘置入胰管支架37例(88.1%)。总治愈率为90.5%(38/42)。胰瘘平均愈合时间为32.0 d (8 ~ 183 d)。损伤后胰瘘愈合时间(19.0±9.9 d, t=3.50, P=0.002)和手术后胰瘘愈合时间(20.3±10.7 d, t=3.35, P=0.003)均短于急性重症胰腺炎后胰瘘愈合时间(60.0±48.6 d)。合并胰腺假性囊肿的胰瘘愈合时间较不合并胰腺假性囊肿的胰瘘愈合时间长(65.3±55.4 d VS 32.6±23.6 d, t=2.21, P=0.040)。胰瘘治愈率、胰腺愈合时间及不同部位胰瘘ERCP次数差异无统计学意义。术后支架相关并发症2例(4.8%)，1例(2.4%)发生轻度胰腺炎。结论ERPD治疗胰瘘疗效好，并发症少，是治疗胰瘘的重要方法。关键词:支架;胰瘘;内镜下逆行胰引流
{"title":"Clinical value of endoscopic retrograde pancreatic drainage for pancreatic fistula","authors":"Bo Liu, Wei Wang, Xin-Gang Shi, Zhendong Jin, Zhao-Shen Li","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.06.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.06.005","url":null,"abstract":"Objective \u0000To evaluate the clinical value of endoscopic retrograde pancreatic drainage (ERPD) in patients with pancreatic fistula. \u0000 \u0000 \u0000Methods \u0000Data of 42 patients with pancreatic fistula, who were treated with ERPD at Changhai Hospital and Henan Provincial People's Hospital from June 2013 to September 2018, were collected. The pancreatic fistula curative rate, healing duration of pancreatic fistula, and the incidence of complications were analyzed. \u0000 \u0000 \u0000Results \u0000Among 42 patients with pancreatic fistula, there were 30 males (71.4%) and 12 females (28.6%) with mean age of 41.5±12.8 years old. Pancreatic duct stents of 37 cases (88.1%) went across the fistula. The overall curative rate was 90.5% (38/42) . The median healing duration of pancreatic fistula was 32.0 d (8-183 d) . The healing time of pancreatic fistula after injury (19.0±9.9 d, t=3.50, P=0.002) and of pancreatic fistula after surgery (20.3±10.7 d, t=3.35, P=0.003) were shorter than that of pancreatic fistula after acute severe pancreatitis (60.0±48.6 d) . The healing time of pancreatic fistula with pancreatic pseudocysts was longer than that of pancreatic fistula without pancreatic pseudocysts (65.3±55.4 d VS 32.6±23.6 d, t=2.21, P=0.040) . There were no significant differences in pancreatic fistula curative rate, pancreatic healing duration and times of ERCP in pancreatic fistula at different position.Postoperative stent-related complications occurred in 2 patients (4.8%) , and 1 patient (2.4%) developed mild pancreatitis. \u0000 \u0000 \u0000Conclusion \u0000ERPD is an important treating method with good therapeutic effect and low complications for pancreatic fistula. \u0000 \u0000 \u0000Key words: \u0000Stent; Pancreatic fistula; Endoscopic retrograde pancreatic drainage","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"407-410"},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41568588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.06.009
Yu Bai, L. Jing, Q. Kang, Yushu Chen, Wang Meicong, P. Jin, Yiqun Mi, R. Gao, H. Qin, Zhaoshen Li, N. Qin, J. Sheng
Objective To explore the value of methylation of SDC2 and SFRP2 genes promoter in fecal DNA for colorectal cancer (CRC) screening. Methods All stool samples were enrolled from Changhai Hospital of Naval Medical University, the Tenth People′s Hospital of Tongji University and the Seventh Medical Center of Chinese People′s Liberation Army General Hospital. A total of 500 stool samples collected from March 2018 to December 2018 were allocated to CRC group (132 CRCs) , adenoma group (38 advanced adenomas) , healthy group (152 healthy individuals) , interferential group (178 cases of benign colorectal disease or other non-colorectal tumors) and negative group (330 cases composed of healthy group and interferential group) . The promoter methylation of fecal SDC2 and SFRP2 genes was detected by methylation-specific PCR (MSP) and compared with single gene methylation and the fecal immunochemical tests (FIT) to evaluate its sensitivity and specificity. Results The stool sample analysis showed that the sensitivity of combined detection of SDC2 and SFRP2 in CRC group was 97.73% (129/132) , which was significantly higher than those of the single gene SDC2 test [70.45% (93/132) , P=0.000], single SFRP2 test [81.82% (108/132) , P=0.000] and FIT [69.70% (92/132) , P=0.000]. In adenoma group, the sensitivity of combined detection of SDC2 and SFRP2 was 57.89% (22/38) , which was significantly higher than those of the single gene SDC2 test [15.79% (6/38) , P=0.000] and FIT [21.05% (8/38) , P=0.021], with no significant difference compared with that of SFRP2 test [47.37% (18/38) , P=0.358]. In healthy group, the specificity of combined detection of SDC2 and SFRP2 was 98.68% (150/152) , with no significant difference compared with those of single gene SDC2 test [100.00% (152/152) , P=0.156], single SFRP2 test [98.68% (150/152) , P=1.000] or FIT [95.39% (145/152) , P=0.091]. Specificities of combined detection of two genes in interferential and negative groups were 90.45% (161/178) and 94.24% (311/330) , which were significantly higher than 73.03% (130/178, P=0.000) and 83.33% (275/330, P=0.000) of FIT, respectively. Conclusion The combined detection test of methylation of SDC2 and SFRP2 is superior to single gene test, whose sensitivity of CRC and aggressive adenoma and specificity of distinguishing benign and malignant lesions are higher than FIT, which has potential application value. Key words: Gene components; DNA; Feces; Methylation; Colorectal neoplasms; SDC2/SFRP2
{"title":"Value of the methylation status of SDC2 and SFRP2 for colorectal cancer screening","authors":"Yu Bai, L. Jing, Q. Kang, Yushu Chen, Wang Meicong, P. Jin, Yiqun Mi, R. Gao, H. Qin, Zhaoshen Li, N. Qin, J. Sheng","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.06.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.06.009","url":null,"abstract":"Objective \u0000To explore the value of methylation of SDC2 and SFRP2 genes promoter in fecal DNA for colorectal cancer (CRC) screening. \u0000 \u0000 \u0000Methods \u0000All stool samples were enrolled from Changhai Hospital of Naval Medical University, the Tenth People′s Hospital of Tongji University and the Seventh Medical Center of Chinese People′s Liberation Army General Hospital. A total of 500 stool samples collected from March 2018 to December 2018 were allocated to CRC group (132 CRCs) , adenoma group (38 advanced adenomas) , healthy group (152 healthy individuals) , interferential group (178 cases of benign colorectal disease or other non-colorectal tumors) and negative group (330 cases composed of healthy group and interferential group) . The promoter methylation of fecal SDC2 and SFRP2 genes was detected by methylation-specific PCR (MSP) and compared with single gene methylation and the fecal immunochemical tests (FIT) to evaluate its sensitivity and specificity. \u0000 \u0000 \u0000Results \u0000The stool sample analysis showed that the sensitivity of combined detection of SDC2 and SFRP2 in CRC group was 97.73% (129/132) , which was significantly higher than those of the single gene SDC2 test [70.45% (93/132) , P=0.000], single SFRP2 test [81.82% (108/132) , P=0.000] and FIT [69.70% (92/132) , P=0.000]. In adenoma group, the sensitivity of combined detection of SDC2 and SFRP2 was 57.89% (22/38) , which was significantly higher than those of the single gene SDC2 test [15.79% (6/38) , P=0.000] and FIT [21.05% (8/38) , P=0.021], with no significant difference compared with that of SFRP2 test [47.37% (18/38) , P=0.358]. In healthy group, the specificity of combined detection of SDC2 and SFRP2 was 98.68% (150/152) , with no significant difference compared with those of single gene SDC2 test [100.00% (152/152) , P=0.156], single SFRP2 test [98.68% (150/152) , P=1.000] or FIT [95.39% (145/152) , P=0.091]. Specificities of combined detection of two genes in interferential and negative groups were 90.45% (161/178) and 94.24% (311/330) , which were significantly higher than 73.03% (130/178, P=0.000) and 83.33% (275/330, P=0.000) of FIT, respectively. \u0000 \u0000 \u0000Conclusion \u0000The combined detection test of methylation of SDC2 and SFRP2 is superior to single gene test, whose sensitivity of CRC and aggressive adenoma and specificity of distinguishing benign and malignant lesions are higher than FIT, which has potential application value. \u0000 \u0000 \u0000Key words: \u0000Gene components; DNA; Feces; Methylation; Colorectal neoplasms; SDC2/SFRP2","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"427-432"},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46147340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To study the diagnostic value of Japan narrow band imaging expert team (JNET) classification for differentiating pathological type of colorectal lesions. Methods A total of 418 colorectal lesions were retrospectively diagnosed by magnifying endoscopy with narrow band imaging (ME-NBI) using JNET classification by two inexperienced doctors after a short time of training in JNET classification. Then lesions were diagnosed with Sano classification by the two doctors. Diagnostic results were compared with histologic findings as a golden standard. Results The sensitivity, specificity, and accuracy of JNET classification and Sano classification for neoplastic lesion differentiation were 98.2% VS 98.5%, 77.8% VS 66.7%, and 96.9% VS 96.4%, respectively (all P>0.05). These indicators for diagnosing cancerous lesions, including high grade intraepithelial neoplasia, intramucosal carcinoma and submucosal carcinoma, were 66.7% VS 80.2% (P=0.023), 87.6% VS 79.5% (P=0.006), and 82.1% VS 79.7% (P=0.379), respectively, and those for predicting submucosal deep invasive cancers were 34.8% VS 39.1%, 100.0% VS 99.0%, and 96.4% VS 96.3%, respectively (all P>0.05). The diagnostic accuracy of JNET classification for differentiating neoplastic lesions were 95.2% in those with diameter <10 mm, 97.0% in 10~<20 mm, and 97.8% in ≥20 mm (P=0.483), this finding were 95.2%, 85.1% and 72.1% for cancer, respectively (P<0.000 1), and 100%, 96.3%, and 94.4% for submucosal deep invasive cancer, respectively (P=0.026). Shape and location of colorectal lesions showed no significant effect on the diagnostic efficacy of JNET classification. Conclusion JNET classification is valuable for doctors without experience of ME-NBI in diagnosing colorectal lesions and the efficiency is slightly superior to Sano classification. However, the accuracy of diagnosis for cancer with diameter ≥20 mm need to be improved. Key words: Intestinal polyp; Diagnostic techniques, digestive system; Diagnostic imaging; JNET classification
目的探讨日本窄带成像专家组(JNET)分级对结直肠病变病理类型的诊断价值。方法对418例结直肠病变进行回顾性诊断，由两名经验不足的医生在接受短时间的JNET分类培训后，采用窄带放大内镜(ME-NBI)进行JNET分类。然后由两位医生对病变进行Sano分型诊断。诊断结果比较组织学表现作为金标准。结果JNET分型和Sano分型对肿瘤病变鉴别的敏感性、特异性和准确性分别为98.2%比98.5%、77.8%比66.7%、96.9%比96.4%(均P < 0.05)。高级别上皮内瘤变、粘膜内癌、粘膜下癌的诊断指标分别为66.7% VS 80.2% (P=0.023)、87.6% VS 79.5% (P=0.006)、82.1% VS 79.7% (P=0.379)，预测粘膜下深部浸润性癌的诊断指标分别为34.8% VS 39.1%、100.0% VS 99.0%、96.4% VS 96.3% (P均为0.05)。JNET分类对直径<10 mm的诊断准确率为95.2%，10~<20 mm的诊断准确率为97.0%，≥20 mm的诊断准确率为97.8% (P=0.483)，对肿瘤的诊断准确率分别为95.2%、85.1%和72.1% (P<0.000 1)，对粘膜下深部浸润癌的诊断准确率分别为100%、96.3%和94.4% (P=0.026)。结直肠病变的形状和位置对JNET分级的诊断效果无显著影响。结论JNET分型对没有ME-NBI经验的医生诊断结直肠病变有一定的价值，其诊断效率略优于Sano分型。但对于直径≥20mm的肿瘤，其诊断准确率有待提高。关键词:肠息肉;诊断技术，消化系统;诊断成像;JNET分类
{"title":"Clinical value of JNET classification for non-real-time diagnosis of colorectal lesions","authors":"Jing Zhou, Qing-Wei Zhang, Jian Huang, La-Mei Teng, Zhenbo Qin, Xintian Zhang, Jin-Nan Chen","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.05.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.05.006","url":null,"abstract":"Objective \u0000To study the diagnostic value of Japan narrow band imaging expert team (JNET) classification for differentiating pathological type of colorectal lesions. \u0000 \u0000 \u0000Methods \u0000A total of 418 colorectal lesions were retrospectively diagnosed by magnifying endoscopy with narrow band imaging (ME-NBI) using JNET classification by two inexperienced doctors after a short time of training in JNET classification. Then lesions were diagnosed with Sano classification by the two doctors. Diagnostic results were compared with histologic findings as a golden standard. \u0000 \u0000 \u0000Results \u0000The sensitivity, specificity, and accuracy of JNET classification and Sano classification for neoplastic lesion differentiation were 98.2% VS 98.5%, 77.8% VS 66.7%, and 96.9% VS 96.4%, respectively (all P>0.05). These indicators for diagnosing cancerous lesions, including high grade intraepithelial neoplasia, intramucosal carcinoma and submucosal carcinoma, were 66.7% VS 80.2% (P=0.023), 87.6% VS 79.5% (P=0.006), and 82.1% VS 79.7% (P=0.379), respectively, and those for predicting submucosal deep invasive cancers were 34.8% VS 39.1%, 100.0% VS 99.0%, and 96.4% VS 96.3%, respectively (all P>0.05). The diagnostic accuracy of JNET classification for differentiating neoplastic lesions were 95.2% in those with diameter <10 mm, 97.0% in 10~<20 mm, and 97.8% in ≥20 mm (P=0.483), this finding were 95.2%, 85.1% and 72.1% for cancer, respectively (P<0.000 1), and 100%, 96.3%, and 94.4% for submucosal deep invasive cancer, respectively (P=0.026). Shape and location of colorectal lesions showed no significant effect on the diagnostic efficacy of JNET classification. \u0000 \u0000 \u0000Conclusion \u0000JNET classification is valuable for doctors without experience of ME-NBI in diagnosing colorectal lesions and the efficiency is slightly superior to Sano classification. However, the accuracy of diagnosis for cancer with diameter ≥20 mm need to be improved. \u0000 \u0000 \u0000Key words: \u0000Intestinal polyp; Diagnostic techniques, digestive system; Diagnostic imaging; JNET classification","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"328-333"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48186667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To explore the effectiveness of endoscopic ultrasound(EUS)-guided holmium laser ablation for primary pancreatic implantation tumor in nude mice. Methods Pancreatic cancer cell line SW1990 were implanted into 20 4-6-week-old male balb/c nude mice to establish primary pancreatic implantation tumor in situ models. Then the nude mice were randomly divided into two groups, the treatment group(n=10) and the control group(n=10). The treatment group underwent EUS-guided holmium laser ablation in the pancreatic tumor. And no interventions were given to the control group. The volume of tumors of the two groups were measured under EUS at time points of 7 d, 14 d and 28 d after ablation. The activities, appetites and psychosis of all nude mice were evaluated in the meantime. At 28 d after ablation, lesions of pancreas were dissected and sliced for H&E staining. Results There were no complications in the treatment group, and all nude mice could tolerate the procedure. The mental state, activities and appetites of nude mice in the experimental group were better than those in the control group. Tumors of the control group enlarged. There was significant difference in the tumor size between the two groups at 28 d after ablation. HE staining showed coagulation necrosis in the ablation area. Conclusion EUS-guided holmium laser, producing coagulative necrosis in the ablation area, is effective for primary pancreatic implantation carcinoma in nude mice for about 28 days. Key words: Ultrasonography; Laser therapy, Holmium; Disease modelsl; Rats, nude
{"title":"Therapeutic effects of endoscopic ultrasound-guided holmium laser ablation for pancreatic primary implantation carcinoma in nude mice","authors":"Ling Xing, Jianwei Zhu, Dong Wang, Hongyu Wu, Xiaolan Zhang, Zhendong Jin, Bing Hu","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.05.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.05.010","url":null,"abstract":"Objective \u0000To explore the effectiveness of endoscopic ultrasound(EUS)-guided holmium laser ablation for primary pancreatic implantation tumor in nude mice. \u0000 \u0000 \u0000Methods \u0000Pancreatic cancer cell line SW1990 were implanted into 20 4-6-week-old male balb/c nude mice to establish primary pancreatic implantation tumor in situ models. Then the nude mice were randomly divided into two groups, the treatment group(n=10) and the control group(n=10). The treatment group underwent EUS-guided holmium laser ablation in the pancreatic tumor. And no interventions were given to the control group. The volume of tumors of the two groups were measured under EUS at time points of 7 d, 14 d and 28 d after ablation. The activities, appetites and psychosis of all nude mice were evaluated in the meantime. At 28 d after ablation, lesions of pancreas were dissected and sliced for H&E staining. \u0000 \u0000 \u0000Results \u0000There were no complications in the treatment group, and all nude mice could tolerate the procedure. The mental state, activities and appetites of nude mice in the experimental group were better than those in the control group. Tumors of the control group enlarged. There was significant difference in the tumor size between the two groups at 28 d after ablation. HE staining showed coagulation necrosis in the ablation area. \u0000 \u0000 \u0000Conclusion \u0000EUS-guided holmium laser, producing coagulative necrosis in the ablation area, is effective for primary pancreatic implantation carcinoma in nude mice for about 28 days. \u0000 \u0000 \u0000Key words: \u0000Ultrasonography; Laser therapy, Holmium; Disease modelsl; Rats, nude","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"350-354"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49337522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.05.009
C. Peng, Hongzhen Li, Chengfei Jiang, D. Tang, Shanshan Shen, Song Zhang, B. Kong, Lei Wang, X. Zou
Objective To determine the diagnostic value of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for gastrointestinal lesions with inconclusive endoscopic biopsies. Methods A retrospective analysis was performed in 65 patients who were found to have gastrointestinal lesions with inconclusive endoscopic biopsies and underwent EUS-FNA in Drum Tower Hospital. Diagnostic value of EUS-FNA was determined by comparing with surgical histopathology and follow-up results. Results This study included 41 males (63%) and 24 females (37%) with median age of 60 years. The most common lesion was diffuse infiltrative lesions (37, 56.9%), followed by submucosal protrusion types (17, 26.2%). Fifty-four cases (83.1%) were malignant lesions, and 11 cases (16.9%) were benign. The overall sensitivity, specificity, and accuracy of EUS-FNA for gastrointestinal lesions with inconclusive biopsies were 76.8% (95%CI: 65.7%-87.8%), 100.0% (95%CI: 66.4%-100.0%), and 80.0% (95%CI: 70.3%-89.7%), respectively. Sub-group analysis showed the sensitivity, specificity, and accuracy of EUS-FNA for diffuse infiltrative lesions were 70.6% (95%CI: 55.3%-85.9%, 100.0% (95%CI: 29.2%-100.0%), and 73.0% (95%CI: 58.7%-87.3%), respectively. For submucosal protrusions, the sensitivity, specificity, and accuracy of EUS-FNA were 68.8% (95%CI: 46.0%-91.5%), 100.0% (95%CI: 2.5%-100.0%), and 70.6% (95%CI: 44.0%-89.7%), respectively. Conclusion EUS-FNA has moderate diagnostic value for endoscopic biopsy-inconclusive gastrointestinal lesions. It can be an alternative option when standard methods, such as endoscopic mucosal forceps biopsy, fail to provide a definitive diagnosis. Key words: Biopsy, fine-needle; Ultrasonography; Endoscopy, gastrointestinal; Diagnosis
{"title":"Endoscopic ultrasound-guided fine needle aspiration for gastrointestinal lesions with inconclusive endoscopic biopsies","authors":"C. Peng, Hongzhen Li, Chengfei Jiang, D. Tang, Shanshan Shen, Song Zhang, B. Kong, Lei Wang, X. Zou","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.05.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.05.009","url":null,"abstract":"Objective \u0000To determine the diagnostic value of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for gastrointestinal lesions with inconclusive endoscopic biopsies. \u0000 \u0000 \u0000Methods \u0000A retrospective analysis was performed in 65 patients who were found to have gastrointestinal lesions with inconclusive endoscopic biopsies and underwent EUS-FNA in Drum Tower Hospital. Diagnostic value of EUS-FNA was determined by comparing with surgical histopathology and follow-up results. \u0000 \u0000 \u0000Results \u0000This study included 41 males (63%) and 24 females (37%) with median age of 60 years. The most common lesion was diffuse infiltrative lesions (37, 56.9%), followed by submucosal protrusion types (17, 26.2%). Fifty-four cases (83.1%) were malignant lesions, and 11 cases (16.9%) were benign. The overall sensitivity, specificity, and accuracy of EUS-FNA for gastrointestinal lesions with inconclusive biopsies were 76.8% (95%CI: 65.7%-87.8%), 100.0% (95%CI: 66.4%-100.0%), and 80.0% (95%CI: 70.3%-89.7%), respectively. Sub-group analysis showed the sensitivity, specificity, and accuracy of EUS-FNA for diffuse infiltrative lesions were 70.6% (95%CI: 55.3%-85.9%, 100.0% (95%CI: 29.2%-100.0%), and 73.0% (95%CI: 58.7%-87.3%), respectively. For submucosal protrusions, the sensitivity, specificity, and accuracy of EUS-FNA were 68.8% (95%CI: 46.0%-91.5%), 100.0% (95%CI: 2.5%-100.0%), and 70.6% (95%CI: 44.0%-89.7%), respectively. \u0000 \u0000 \u0000Conclusion \u0000EUS-FNA has moderate diagnostic value for endoscopic biopsy-inconclusive gastrointestinal lesions. It can be an alternative option when standard methods, such as endoscopic mucosal forceps biopsy, fail to provide a definitive diagnosis. \u0000 \u0000 \u0000Key words: \u0000Biopsy, fine-needle; Ultrasonography; Endoscopy, gastrointestinal; Diagnosis","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"344-349"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45347334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.05.003
J. Zou, N. Chai, E. Linghu, M. Chai, Zantao Wang, Longsong Li, Xiangyao Wang, Wengang Zhang, J. Xiang, Jing Zhu, Ping Tang
Objective To assess the efficacy and safety of autologous skin-grafting surgery (ASGS) in the prevention of esophageal stenosis after complete circular endoscopic submucosal tunnel dissection (ESTD) for early esophageal cancer. Methods Between January 2018 and March 2018, five patients with early esophageal cancer underwent complete circular ESTD and ASGS in Chinese PLA General Hospital. The skin-graft survival situation, and occurrence of esophageal stenosis and complications were observed by endoscopy follow-up. Results Complete circular ESTD and ASGS were successfully performed in all 5 patients, and no complications including perforation, bleeding, wound infection or stent migration occurred. The mean skin-graft survival rate was 86.0%. Four patients did not experience esophageal stenosis over the mean follow-up of 9.5 months. One patient experienced esophageal stenosis after operation, and underwent endoscopic balloon dilatation.No stenosis occurred in 8 months of follow-up. Conclusion ASGS is a safe and effective method to prevent esophageal stenosis after complete circular ESTD Key words: Esophageal stenosis; Transplantation, autologous; Efficacy; Safety; Early esophageal cancer; Endoscopic submucosal tunnel dissection
{"title":"Clinical value of autologous skin-grafting surgery to prevent esophageal stenosis after complete circular endoscopic submucosal tunnel dissection for early esophageal cancer","authors":"J. Zou, N. Chai, E. Linghu, M. Chai, Zantao Wang, Longsong Li, Xiangyao Wang, Wengang Zhang, J. Xiang, Jing Zhu, Ping Tang","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.05.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.05.003","url":null,"abstract":"Objective \u0000To assess the efficacy and safety of autologous skin-grafting surgery (ASGS) in the prevention of esophageal stenosis after complete circular endoscopic submucosal tunnel dissection (ESTD) for early esophageal cancer. \u0000 \u0000 \u0000Methods \u0000Between January 2018 and March 2018, five patients with early esophageal cancer underwent complete circular ESTD and ASGS in Chinese PLA General Hospital. The skin-graft survival situation, and occurrence of esophageal stenosis and complications were observed by endoscopy follow-up. \u0000 \u0000 \u0000Results \u0000Complete circular ESTD and ASGS were successfully performed in all 5 patients, and no complications including perforation, bleeding, wound infection or stent migration occurred. The mean skin-graft survival rate was 86.0%. Four patients did not experience esophageal stenosis over the mean follow-up of 9.5 months. One patient experienced esophageal stenosis after operation, and underwent endoscopic balloon dilatation.No stenosis occurred in 8 months of follow-up. \u0000 \u0000 \u0000Conclusion \u0000ASGS is a safe and effective method to prevent esophageal stenosis after complete circular ESTD \u0000 \u0000 \u0000Key words: \u0000Esophageal stenosis; Transplantation, autologous; Efficacy; Safety; Early esophageal cancer; Endoscopic submucosal tunnel dissection","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"312-316"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47481131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-20DOI: 10.3760/CMA.J.ISSN.1007-5232.2019.05.008
H. Su, Hai‐hong Wang, Lili Liu, Tao Cheng, Yuqi He, P. Jin, Lang Yang, J. Sheng
Objective To study the differences of endoscopic submucosal dissection (ESD) for colorectal tumors of different diameters. Methods Data of 210 cases which were treated with ESD for colorectal tumors at the Endoscopy Center, the Seventh Medical Center of PLA General Hospital from October 2012 to December 2015 were retrospectively analyzed. The lesions were divided into two groups according to different diameters (≥4.0 cm group and <4.0 cm group) for comparative analysis of related factors. Results The mean procedure time of ESD for 210 colorectal tumor cases was 50.3±42.7 min and the mean size of lesions was 7.98±10.84 cm2 . En bloc resection rate was 91.4%, R0 resection rate was 90.5%, and the curative resection rate was 88.6%. Perforation rate was 5.2% (11/210), and the late hemorrhage rate was 0.5% (1/210). Compared with lesions < 4.0 cm, those ≥ 4.0 cm required longer resection time (79.63±53.91 min VS 35.28±24.99 min, P<0.001); and the lesions were mainly located in the rectum (61.97%). LSTs were mainly mixed granular/nongranular type (54.93%); en bloc resection rate, complete resection rate and curative resection rate of the tumors ≥ 4.0 cm were all lower than those of tumors < 4.0 cm. The difference in complete resection rate was statistically significant (85.92% VS 94.24%; P=0.041). The perforation rate (7.04%) was higher in ≥ 4.0 cm group, but the difference was not statistically significant. Conclusions ESD of colorectal tumors of diameters ≥ 4.0 cm requires longer time with higher operation risk. Additionally, physicians should be more careful with non-rectal lesions. Key words: Colorectal cancer; Endoscopic submucosal dissection; Tumor diameter; Difference
目的探讨内镜下粘膜下剥离术(ESD)在不同直径结直肠肿瘤中的应用差异。方法回顾性分析2012年10月至2015年12月解放军总医院第七医学中心内镜中心210例结肠肿瘤行ESD治疗的资料。根据病变直径不同分为≥4.0 cm组和<4.0 cm组，对比分析相关因素。结果210例结直肠肿瘤的平均手术时间为50.3±42.7 min，平均病灶大小为7.98±10.84 cm2。整体切除率为91.4%，R0切除率为90.5%，治愈率为88.6%。穿孔率5.2%(11/210)，晚期出血率0.5%(1/210)。与< 4.0 cm的病变相比，≥4.0 cm的病变需要更长的切除时间(79.63±53.91 min VS 35.28±24.99 min, P<0.001);病变主要位于直肠(61.97%)。lst以颗粒/非颗粒混合型为主(54.93%);≥4.0 cm的肿瘤整体切除率、完全切除率和治愈率均低于< 4.0 cm的肿瘤。两组全切除率差异有统计学意义(85.92% VS 94.24%;P = 0.041)。≥4.0 cm组穿孔率(7.04%)较高，但差异无统计学意义。结论直径≥4.0 cm的结直肠肿瘤ESD手术时间较长，手术风险较高。此外，医生应该更加小心非直肠病变。关键词:结直肠癌;内镜下粘膜下剥离;肿瘤直径;区别
{"title":"Therapeutic value of endoscopic submucosal dissection for early colorectal cancers and precancerous colorectal lesions of different diameters","authors":"H. Su, Hai‐hong Wang, Lili Liu, Tao Cheng, Yuqi He, P. Jin, Lang Yang, J. Sheng","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.05.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.05.008","url":null,"abstract":"Objective \u0000To study the differences of endoscopic submucosal dissection (ESD) for colorectal tumors of different diameters. \u0000 \u0000 \u0000Methods \u0000Data of 210 cases which were treated with ESD for colorectal tumors at the Endoscopy Center, the Seventh Medical Center of PLA General Hospital from October 2012 to December 2015 were retrospectively analyzed. The lesions were divided into two groups according to different diameters (≥4.0 cm group and <4.0 cm group) for comparative analysis of related factors. \u0000 \u0000 \u0000Results \u0000The mean procedure time of ESD for 210 colorectal tumor cases was 50.3±42.7 min and the mean size of lesions was 7.98±10.84 cm2 . En bloc resection rate was 91.4%, R0 resection rate was 90.5%, and the curative resection rate was 88.6%. Perforation rate was 5.2% (11/210), and the late hemorrhage rate was 0.5% (1/210). Compared with lesions < 4.0 cm, those ≥ 4.0 cm required longer resection time (79.63±53.91 min VS 35.28±24.99 min, P<0.001); and the lesions were mainly located in the rectum (61.97%). LSTs were mainly mixed granular/nongranular type (54.93%); en bloc resection rate, complete resection rate and curative resection rate of the tumors ≥ 4.0 cm were all lower than those of tumors < 4.0 cm. The difference in complete resection rate was statistically significant (85.92% VS 94.24%; P=0.041). The perforation rate (7.04%) was higher in ≥ 4.0 cm group, but the difference was not statistically significant. \u0000 \u0000 \u0000Conclusions \u0000ESD of colorectal tumors of diameters ≥ 4.0 cm requires longer time with higher operation risk. Additionally, physicians should be more careful with non-rectal lesions. \u0000 \u0000 \u0000Key words: \u0000Colorectal cancer; Endoscopic submucosal dissection; Tumor diameter; Difference","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"339-343"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42136743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To investigate feasibility of bowel preparation for colonoscopy in endoscopic ambulatory surgery ward. Methods A total of 352 patients at endoscopic ambulatory surgery ward receiving colonoscopy at Zhongshan Hospital, Fudan University from May 25, 2018 to July 13, 2018 were surveyed by questionnaires. Data of 344 patients, including patient demographics, bowel preparation information and Boston bowel preparation scores and subjective perception of patients were analyzed. Data of 8 others were excluded because they did not complete colonoscopy for the first time due to failure of bowel preparation. Chi-square test and logistic regression analysis were conducted to analyze the quality of bowel preparation and its influencing factors. Results A total of 18.0%(62/344) of bowel preparations were inadequate. Morning colonoscopy (P=0.005, OR=2.505, 95%CI: 1.312-4.781) and yellow residual last stool before colonoscopy (P=0.045, OR=0.475, 95%CI: 0.230-0.982) were independent risk factors for inadequate bowel preparation. Patients' tolerance was 88.1%(303/344), satisfaction was 77.9%(268/344), and 54.9%(189/344) were willing to be hospitalized in ambulatory surgery ward again if necessary. Conclusion Bowel preparation before colonoscopy in endoscopic ambulatory surgery ward is feasible but not optimal. Key words: Colonoscopy; Ambulatory surgery ward; Bowel Preparation
{"title":"Feasibility of bowel preparation before colonoscopy in endoscopic ambulatory surgery ward","authors":"Xian-li Cai, Yuehong Shen, Quan-Lin Li, Pin Wang, P. Zhou, Wei-feng Chen","doi":"10.3760/CMA.J.ISSN.1007-5232.2019.05.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-5232.2019.05.007","url":null,"abstract":"Objective \u0000To investigate feasibility of bowel preparation for colonoscopy in endoscopic ambulatory surgery ward. \u0000 \u0000 \u0000Methods \u0000A total of 352 patients at endoscopic ambulatory surgery ward receiving colonoscopy at Zhongshan Hospital, Fudan University from May 25, 2018 to July 13, 2018 were surveyed by questionnaires. Data of 344 patients, including patient demographics, bowel preparation information and Boston bowel preparation scores and subjective perception of patients were analyzed. Data of 8 others were excluded because they did not complete colonoscopy for the first time due to failure of bowel preparation. Chi-square test and logistic regression analysis were conducted to analyze the quality of bowel preparation and its influencing factors. \u0000 \u0000 \u0000Results \u0000A total of 18.0%(62/344) of bowel preparations were inadequate. Morning colonoscopy (P=0.005, OR=2.505, 95%CI: 1.312-4.781) and yellow residual last stool before colonoscopy (P=0.045, OR=0.475, 95%CI: 0.230-0.982) were independent risk factors for inadequate bowel preparation. Patients' tolerance was 88.1%(303/344), satisfaction was 77.9%(268/344), and 54.9%(189/344) were willing to be hospitalized in ambulatory surgery ward again if necessary. \u0000 \u0000 \u0000Conclusion \u0000Bowel preparation before colonoscopy in endoscopic ambulatory surgery ward is feasible but not optimal. \u0000 \u0000 \u0000Key words: \u0000Colonoscopy; Ambulatory surgery ward; Bowel Preparation","PeriodicalId":10072,"journal":{"name":"Chinese Journal of Digestive Endoscopy","volume":"36 1","pages":"334-338"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47742570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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