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Efficacy of soluble hyaluronic acid microneedle on removing suborbital wrinkles 可溶性透明质酸微针去除眶下皱纹的疗效观察
Pub Date : 2019-12-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.06.010
Yan Zhao, L. Xiang, Hui Xu, Jianzhong Zhang
Objective To investigate the clinical efficacy and safety of soluble hyaluronic acid microneedle eye patch on infraorbital wrinkles. Methods Seventy-five female subjects in Beijing and Shanghai were recruited and treated with soluble hyaluronic acid microneedle patch two days a week at the left lower eyelid (experimental side) and at least 30 minutes each time for 12 weeks. Investigator visual assessment, instrumentation measurement for skin moisture, elasticity, wrinkle area and depth were performed at week 0 (pre-treatment) and week 4 and week 12 and compared to the right (control side). The safety was assessed by documenting adverse reactions occurring during the study. Subject satisfaction was assessed at week 12. Results After 12 weeks of treatment, the visual assessment of skin wrinkles on experimental side (n=41, 54.67%) was significantly improved as comparied with that on control side (n=14, 18.67%). The skin hydration of treatment side skin increased with treatment time (t=-0.488 at week4, t=-3.054 at week 12, P<0.05). After 12 weeks of treatment, skin elasticity of the experimental side improved significantly. The improvement rate of the experimental side was more than that of the control side (t=2.724, P<0.05). The wrinkle area was significantly decreased in 4 and 12 weeks compared with pre-treatment (t=4.442 at week 4 and t=3.802 at week 12, P<0.001). The depth of wrinkles of the experimental side shallowed with the treatment (t=-2.435 at week 4 and t=-3.433 at week 12, P<0.05). Only 8% (n=6) of the subjects had temporary slight pruritus or acupuncture sensation on the treatment side, and no other adverse reactions occurred. The overall subject satisfaction rate was 88%(n=66). Conclusions Soluble hyaluronic acid microneedle eye patch is effective in improving wrinkles, skin elasticity and hydrating, and has no obvious adverse reaction. Key words: Hyaluronic acid; Solublemicroneedles; Suborbitalwrinkle; Skin elasticity; Skin hydration
目的探讨可溶性透明质酸微针眼罩治疗眶下皱纹的临床疗效和安全性。方法北京和上海的75名女性受试者,每周2天(实验侧)在左下眼睑使用可溶性透明质酸微针贴片,每次至少30分钟,持续12周。在第0周(预处理)、第4周和第12周进行研究者视觉评估,仪器测量皮肤水分、弹性、皱纹面积和深度,并与右侧(对照侧)进行比较。通过记录研究期间发生的不良反应来评估安全性。在第12周评估受试者满意度。结果治疗12周后,实验侧(n=41,54.67%)皮肤皱纹的视觉评估与对照侧(n=14,18.67%)相比有显著改善。治疗侧皮肤的水合作用随着治疗时间的延长而增加(t=-0.488,t=-3.054,P<0.05),实验侧皮肤弹性明显改善。实验侧的改善率高于对照侧(t=2.724,P<0.05)。与治疗前相比,第4周和第12周皱纹面积显著减少(第4周t=4.442,第12周t=3.802,P<0.001)。实验侧的皱纹深度随着治疗而变浅(第4周t=-2.435,第12周t=-3.433,P<0.05)受试者在治疗侧有短暂的轻微瘙痒或针刺感觉,没有发生其他不良反应。受试者的总体满意度为88%(n=66)。结论可溶性透明质酸微针眼罩对改善皱纹、皮肤弹性和补水效果显著,无明显不良反应。关键词:透明质酸;可溶性微针;眶下皱纹;皮肤弹性;皮肤水合作用
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引用次数: 1
Cognitive status of Chinese acne patients and its influencing factors 中国痤疮患者的认知状况及其影响因素
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.016
Shuyun Yang, Ying Tu, Jianting Yang, Rong Jin, Yanni Guo, Xinyu Lin, Ying Qiu, Hongxia Liu, Yao Xie, Yuzhen Li, L. Xiang, B. Yu, Xian-bin Zeng, Changchun Xu, Fengyan Lu, Xing Li, Hua Du, Xiangfei Lin, Y. Qiu, F. Zhu, Yufu Fang, M. Lyu, Ruina Zhang, Xin-Xin Hu, L. Jiao, Hongxia Feng, X. Bi, Min Zhang, Biwen Lin, Qiao-min Liu, Yong-hong Lu, Li He
Objective To indentify the cognitive status of Chinese patients to acne and the influencing factors to theirs' cognitive status, so as to provide solid evidences for the prevention and treatment of acne. Methods A self-designed questionnaire was made to conduct this survey of 16, 156 acne patients, who seeked to the treatment in the dermatological departments from 112 hospitals in China. The survey consisted of several parts, including the general status of patients, the patients' cognition of occurrence, development and risk factors of acne, whether the first choice was seeking treatment at the hospital when the patients had acne and the condition of selection of skin care products. The factors were analyzed, which could impact the cognition of the patients' behavior of treatment, how did the patients' cognition to influence their medical behavior and skin care as well as the consistency of assessment of the severity of acne by doctors and patients themselves. Results The acne patients studied had the best knowledge of " acne is a skin disease" , " it not only occurs in the period of adolescence" and " the disease can be prevented and cured" , which accordingly accounted for 80.65%, 69.16% and 65.49% of the total patients respectively. However, the awareness of acne patients to heredity, high sugar and dairy products as risk factors for acne was insufficient, which accounted for 48.72%, 42.40% and 18.25% of the total patients, respectively. Gender, age, educational level, occupation and health knowledge were the main factors affecting the cognitive level of patients; the survey also found that men, patient with educational level of junior high or even lower educational condition, occupation of labor workers or farmers and patients were lack of health education with poor knowledge of the genetics and dietary were risk factors for acne; patients with age over 36 years or with mild illness had poor knowledge of dietary risk factors for acne; the difference was statistically significant (P<0.05). The analysis of the influence of cognitive status on medical treatment behavior and skin care showed that the better the cognition, the higher the probability of patients would choose medical treatment as the first choice as well as choosing functional skin care products; the difference was statistically significant (P<0.05). The consistency of assessment of the severity of acne by doctors and patients was poor (Kappa value <0.4), and the assessment of severity of acne by patients was more serious than doctors' assessment. Conclusions Patient's cognitive status will affect their medical behavior and skin care, and there is also a phenomenon that patients have a more serious assessment of their acne condition. It is suggested that health education for acne patients should be strengthened in clinical medicine so as to improve their knowledge of acne as well as preventing from acne effectively. Key words: Acne vulgaris; Questionnaires;
目的了解我国痤疮患者的认知状况及影响其认知状况的因素,为痤疮的防治提供依据。方法采用自行设计的问卷,对全国112家医院皮肤科就诊的16156例痤疮患者进行调查。调查内容包括患者一般情况、患者对痤疮发生、发展及危险因素的认知情况、患者出现痤疮时是否首选到医院就诊、选择护肤品的情况等几个部分。分析影响患者治疗行为认知的因素,患者认知如何影响其医疗行为和皮肤护理,以及医生和患者对痤疮严重程度评估的一致性。结果受访痤疮患者对“痤疮是一种皮肤病”、“痤疮不仅发生在青春期”和“痤疮是可以预防和治愈的”的认知程度最高,分别占总人数的80.65%、69.16%和65.49%。然而,痤疮患者对遗传、高糖和乳制品作为痤疮危险因素的认识不足,分别占总患者的48.72%、42.40%和18.25%。性别、年龄、文化程度、职业、健康知识是影响患者认知水平的主要因素;男性、文化程度为初中及以下的患者、职业为劳动工人或农民、缺乏健康教育、遗传和饮食知识贫乏的患者是发生痤疮的危险因素;年龄在36岁以上或病情较轻的患者对痤疮的饮食危险因素认识不足;差异有统计学意义(P<0.05)。认知状况对就医行为和护肤的影响分析表明,认知状况越好,患者选择就医为第一选择的概率越高,选择功能性护肤品的概率越高;差异有统计学意义(P<0.05)。医患对痤疮严重程度的评价一致性较差(Kappa值<0.4),患者对痤疮严重程度的评价比医生的评价更严重。结论患者的认知状态会影响其就医行为和皮肤护理,患者对自身痤疮状况的评价也较为严重。建议在临床医学中加强对痤疮患者的健康教育,提高患者对痤疮的认识,有效预防痤疮。关键词:寻常痤疮;问卷调查;认知;流行病学;影响因素
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引用次数: 0
Application of serratus anterior muscle flap transfer in lateral part deformity of expander to implant breast reconstruction 前锯肌皮瓣移植在扩张器外侧畸形中的应用
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.013
Hehuan Li, Jiani He, Xiaoying Liu, Nudel'man Li, F. Jin, Siyuan Han
Objective To explore the application and clinical significance of serratus anterior muscle flap transfer in correction of lateral part deformity of expander to implant breast reconstruction. Methods Six patients who received expander-to-implant breast reconstruction were enrolled. After silicone implant replacing the tissue expander, all 6 cases represented lateral part deformity of the reconstructed breast. The turn-over serratus anterior muscle flap was used as lateral coverage of the deformed breast. Results Of all patients (6 cases), breast aesthetics were improved with incisions well-healed. There were no complications such as capsular contracture, hematoma, infection or insicional dehiscence. Conclusions Serratus anterior muscle flap can provide sufficient lateral coverage for expander-to-implant breast reconstruction. It is safe, simple and cheap to apply in improving the aesthetics of breast reconstruction. Key words: Mammaplasty; Reconstructive surgical procedures; Breast reconstruction; Deformity; Serratus anterior muscle flap
目的探讨前锯肌皮瓣移植在矫正扩张器外侧畸形中的应用及临床意义。方法选取6例行扩张器植入乳房重建术的患者。硅胶假体置换组织扩张器后,6例均为重建乳房外侧畸形。翻转前锯肌瓣用于畸形乳房的外侧覆盖。结果所有患者(6例)的乳房美观得到改善,切口愈合良好。无包膜挛缩、血肿、感染、切口开裂等并发症。结论前锯肌皮瓣可为扩张体-假体乳房再造术提供足够的外侧覆盖。该方法安全、简便、经济,可提高乳房再造的美观性。关键词:乳房成形术;重建外科手术;乳房重建;畸形;前锯肌瓣
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引用次数: 0
Effect of 595 nm pulsed dye laser combined with glycolic acid in treatment of acne vulgaris 595nm脉冲染料激光联合乙醇酸治疗寻常痤疮疗效观察
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.007
Yu Liu, Yangmei Chen, Qing Zhao, D. Zou
Objective To observe the clinical efficacy of 595 nm pulsed dye laser and 595 nm pulsed dye laser combined with glycolic acid on patients with acne vulgaris. Methods From October 2017 to October 2018, 60 patients with acne vulgaris (28 men, 32 women, average age of 24.25 years) were divided randomly into two groups: one group was treated by 595 nm pulsed dye laser only, and other group used 595 nm pulsed dye laser combined with glycolic acid. Results The total effective rates of two groups were 50.00% (15/30 cases) and 77.00% (23/30 cases), respectively, and there was a significant statistic difference between the two groups (χ2=4.59, P<0.05). Conclusions Patients with acne vulgaris have more significant benefits from 595 nm pulsed dye laser combind with glycolic acid than the laser alone. Key words: Acne vulgaris; Laser therapy; Effectiveness; 595 nm pulsed dye laser; Glycolic acid
目的观察595nm脉冲染料激光和595nm脉冲激光联合乙醇酸治疗寻常痤疮的临床疗效。方法2017年10月至2018年10月,60例寻常痤疮患者(男28例,女32例,平均年龄24.25岁)随机分为两组:一组仅用595nm脉冲染料激光治疗,另一组用595nm激光脉冲染料激光联合乙醇酸治疗。结果两组总有效率分别为50.00%(15/30例)和77.00%(23/30例),差异有统计学意义(χ2=4.59,P<0.05)。关键词:寻常痤疮;激光治疗;有效性;595nm脉冲染料激光器;乙醇酸
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引用次数: 0
Clinical effectiveness of small needle knife in autologous fat grafting for treatment of atrophic scar 小针刀自体脂肪移植术治疗萎缩性瘢痕的临床疗效
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.006
F-Z Zhu, Songjia Tang, Haiyan Shen, Jinsheng Li, Chun-lin Du
Objective To explore the clinical effect of using small needle knife in autologous fat grafting for the treatment of atrophic scar. Methods Twelve patients with atrophic scar were included in this study during March 2014 and December 2016 in the Hangzhou First People's Hospital, Zhejiang University School of Medicine. We used small needle knife during fat grafting to treat the atrophic scar. Observer Scar Assessment Scale (POSAS) was used to assess the clinical effect of the patients. Results Aesthetic and functional improvements were observed. Resolution of pain and increases in scar elasticity were objectively assessable. Improvement of both clinical evaluation and patient perception was obtained. Conclusions Use of small needle knife during fat grafting is a good alternative for the treatment of atrophic scars. Key words: Cicatrix; Atrophy; Acupotomy therapy; Transplantation, autologous; Adipose tissue
目的探讨小针刀自体脂肪移植术治疗萎缩性瘢痕的临床效果。方法选取2014年3月至2016年12月浙江大学医学院附属杭州第一人民医院收治的萎缩性瘢痕患者12例。我们在脂肪移植术中使用小针刀治疗萎缩性瘢痕。采用观察瘢痕评定量表(POSAS)评价患者的临床疗效。结果观察到美观和功能的改善。疼痛的缓解和疤痕弹性的增加是可以客观评估的。临床评价和患者感知均有改善。结论小针刀脂肪移植术是治疗萎缩性瘢痕的一种较好的方法。关键词:瘢痕;萎缩;Acupotomy疗法;自体移植;脂肪组织
{"title":"Clinical effectiveness of small needle knife in autologous fat grafting for treatment of atrophic scar","authors":"F-Z Zhu, Songjia Tang, Haiyan Shen, Jinsheng Li, Chun-lin Du","doi":"10.3760/CMA.J.ISSN.1671-0290.2019.05.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-0290.2019.05.006","url":null,"abstract":"Objective \u0000To explore the clinical effect of using small needle knife in autologous fat grafting for the treatment of atrophic scar. \u0000 \u0000 \u0000Methods \u0000Twelve patients with atrophic scar were included in this study during March 2014 and December 2016 in the Hangzhou First People's Hospital, Zhejiang University School of Medicine. We used small needle knife during fat grafting to treat the atrophic scar. Observer Scar Assessment Scale (POSAS) was used to assess the clinical effect of the patients. \u0000 \u0000 \u0000Results \u0000Aesthetic and functional improvements were observed. Resolution of pain and increases in scar elasticity were objectively assessable. Improvement of both clinical evaluation and patient perception was obtained. \u0000 \u0000 \u0000Conclusions \u0000Use of small needle knife during fat grafting is a good alternative for the treatment of atrophic scars. \u0000 \u0000 \u0000Key words: \u0000Cicatrix; Atrophy; Acupotomy therapy; Transplantation, autologous; Adipose tissue","PeriodicalId":10094,"journal":{"name":"Chinese Journal of Medical Aesthetics and Cosmetology","volume":"25 1","pages":"372-374"},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46734609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Status of anxiety and depression in male patients with gonococcal infection in paraurethral ducts before and after paraurethral duct dilatation 男性尿道旁管淋球菌感染患者扩张前后的焦虑和抑郁状况
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.020
Wenge Fan, Jing Zhang, Chao Gu, Qinsong Zhang, Min Mao, X. Ye, Zhijiang Fan, Zhong Yang, Ling-ling Wang, Q. Xue, Xiaoyu Tao, Hao Ding, M. Wei, Jun Zhao
Objective To verify the change of the anxiety and depression of patients anterior-posterior treatment at paraurethral duct dilitation after gonococcal infection of paraurethral duct. Methods Twenty-eight patients of paraurethral duct dilatation after male gonococcal infection of paraurethral duct were enrolled, and the patients were treated in the Department of Dermatology and Venerology, the First People's Hospital of Changshu City. The anxiety and depression of patients anterior-posterior treatment were assessed and compared with Hamilton depression scale and Hamilton anxiety scale. Results The total scores of Hamilton depression scale and Hamilton anxiety scale before treatment were positively correlated with course of disease (r=0.481, P=0.0095; r=0.549, P=0.0025). The total scores of Hamilton depression and anxiety before treatment were from 1 to 31 (18.9±7.5) and from 4 to 30 (14.9±6.8). The symptoms of depression and anxiety appeared in 11 patients and 15 patients respectively. The total scores of Hamilton depression andanxiety after treatment were from 0 to 8 (4.3±1.7) and from 0 to 8 (3.3±1.7). There was no symptom of depression and anxiety. The difference of the total score of Hamilton depression and anxiety before and after treatment had statistical significance (t=12.270, P<0.001, t=10.626, P<0.001). The difference of positive rate of depressive and anxious symptom before and after treatment had statistical significance too (χ2=9.05, P=0.003; χ2=13.06, P=0.000). Conclusions The sequelae of gonococcal paraurethral duct infection in male paraurethral duct dilatation can result in the anxiety and depression of patients, which should be treated. Effective therapy can relieve or cure the anxiety and depression of patients without the assistance of psychotropic drugs. Key words: Neisseria gonorrhoeae; Infection; Men; Paraurethral duct dilitation; Anxiety; Depression; Hamilton
目的探讨淋菌性尿道旁管感染后尿道旁管切开术前后患者焦虑、抑郁情绪的变化。方法选择常熟市第一人民医院皮肤性病科男性淋球菌性尿道旁管感染并发尿道旁管扩张患者28例。采用汉密尔顿抑郁量表和汉密尔顿焦虑量表对前后治疗患者的焦虑和抑郁进行评估和比较。结果治疗前汉密尔顿抑郁量表和汉密尔顿焦虑量表总分与病程呈正相关(r=0.481,P=0.0095;r=0.549,P=0.0025),治疗前汉密尔顿焦虑抑郁总分分别为1-31(18.9±7.5)和4-30(14.9±6.8)分别地治疗后汉密尔顿抑郁和焦虑总分分别为0~8分(4.3±1.7)和0~8(3.3±1.7),无抑郁和焦虑症状。汉密尔顿抑郁、焦虑总分治疗前后差异有统计学意义(t=12.270,P<0.001,t=10.626,P<0.001),抑郁、焦虑症状阳性率治疗前后差异也有统计学意义,χ2=9.05,P=0.003;χ2=13.06,P=0.000)男性尿道旁管扩张感染可引起患者的焦虑和抑郁,应予以治疗。有效的治疗可以在没有精神药物帮助的情况下缓解或治愈患者的焦虑和抑郁。关键词:淋球菌;感染;男性;尿道旁导管切开术;焦虑;抑郁症;汉密尔顿
{"title":"Status of anxiety and depression in male patients with gonococcal infection in paraurethral ducts before and after paraurethral duct dilatation","authors":"Wenge Fan, Jing Zhang, Chao Gu, Qinsong Zhang, Min Mao, X. Ye, Zhijiang Fan, Zhong Yang, Ling-ling Wang, Q. Xue, Xiaoyu Tao, Hao Ding, M. Wei, Jun Zhao","doi":"10.3760/CMA.J.ISSN.1671-0290.2019.05.020","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1671-0290.2019.05.020","url":null,"abstract":"Objective \u0000To verify the change of the anxiety and depression of patients anterior-posterior treatment at paraurethral duct dilitation after gonococcal infection of paraurethral duct. \u0000 \u0000 \u0000Methods \u0000Twenty-eight patients of paraurethral duct dilatation after male gonococcal infection of paraurethral duct were enrolled, and the patients were treated in the Department of Dermatology and Venerology, the First People's Hospital of Changshu City. The anxiety and depression of patients anterior-posterior treatment were assessed and compared with Hamilton depression scale and Hamilton anxiety scale. \u0000 \u0000 \u0000Results \u0000The total scores of Hamilton depression scale and Hamilton anxiety scale before treatment were positively correlated with course of disease (r=0.481, P=0.0095; r=0.549, P=0.0025). The total scores of Hamilton depression and anxiety before treatment were from 1 to 31 (18.9±7.5) and from 4 to 30 (14.9±6.8). The symptoms of depression and anxiety appeared in 11 patients and 15 patients respectively. The total scores of Hamilton depression andanxiety after treatment were from 0 to 8 (4.3±1.7) and from 0 to 8 (3.3±1.7). There was no symptom of depression and anxiety. The difference of the total score of Hamilton depression and anxiety before and after treatment had statistical significance (t=12.270, P<0.001, t=10.626, P<0.001). The difference of positive rate of depressive and anxious symptom before and after treatment had statistical significance too (χ2=9.05, P=0.003; χ2=13.06, P=0.000). \u0000 \u0000 \u0000Conclusions \u0000The sequelae of gonococcal paraurethral duct infection in male paraurethral duct dilatation can result in the anxiety and depression of patients, which should be treated. Effective therapy can relieve or cure the anxiety and depression of patients without the assistance of psychotropic drugs. \u0000 \u0000 \u0000Key words: \u0000Neisseria gonorrhoeae; Infection; Men; Paraurethral duct dilitation; Anxiety; Depression; Hamilton","PeriodicalId":10094,"journal":{"name":"Chinese Journal of Medical Aesthetics and Cosmetology","volume":"25 1","pages":"422-426"},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45797159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence factors of facial melanin situation in male construction workers in Beijing 北京市男性建筑工人面部黑色素状况的影响因素
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.017
Chun-ting Li, Yao Qin, Xiaodan Chang, S. Dai
Objective To investigate the present situation of facial melanin of construction workers in Beijing area, to discuss the relative affecting factors, and to provide theoretical basis for theoretical research on photoaging and occupational protection for construction workers. Methods A total of 157 healthy male construction workers and 61 non-construction workers in Beijing were selected to conduct a questionnaire survey on their exposure to dust, sunlight, noise and high temperature in their working environment. The occurrence of melanin in their face skin was measured by melanin index (melanin index, MI) probe. T test, Spearman rank correlation analysis and multiple logistic regression were used for statistical analysis on two independent samples. Results The exposure of construction workers to dust, sunlight, noise and high temperature was significantly higher than that of non-construction workers (P<0.05); the melanin score of construction workers over 40 years old was significantly higher than that of non-construction workers (P<0.05) and positively correlated with age (P<0.05); the melanin of construction workers was affected by age, sunlight and noise (P<0.05). Conclusions The melanin level of the construction workers aged over 40 is significantly higher than that of the non-construction workers in Beijing. Age, sunlight and noise are the main factors affecting the melanin level. Key words: Construction industry; Melanins; Questionnaires; Age factors; Noise; Sunlight
目的了解北京地区建筑工人面部黑色素的现状,探讨相关影响因素,为建筑工人光老化及职业防护的理论研究提供理论依据。方法选择北京市157名健康男性建筑工人和61名非建筑工人,对他们在工作环境中暴露于灰尘、阳光、噪音和高温的情况进行问卷调查。通过黑色素指数(黑色素指数,MI)探针测量他们面部皮肤中黑色素的出现。采用T检验、Spearman秩相关分析和多元逻辑回归对两个独立样本进行统计分析。结果建筑工人暴露于粉尘、阳光、噪声和高温的程度明显高于非建筑工人(P<0.05);40岁以上建筑工人的黑色素得分显著高于非建筑工人(P<0.05),且与年龄呈正相关(P<0.05);结论北京市40岁以上建筑工人黑色素水平明显高于非建筑工人。年龄、阳光和噪音是影响黑色素水平的主要因素。关键词:建筑业;黑色素;调查表;年龄因素;噪声;阳光
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引用次数: 0
Survival rate of cryopreserved rat fat granuales after autologous transplantation 冷冻保存大鼠脂肪颗粒自体移植后的存活率
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.021
Shaohua Wang
Objective To observe the fat particles survival situations in autologous transplantation under different conditions of low temperature. Methods Three sample groups of adult Wistar rats were injected with fresh autologous fat particles, which were stored under 80 ℃ for two months and under 196 ℃ for two months respectively, and the volume, parallel histological detection, glucose transport measurement, MTT experiments and other data were compared and analyzed one month and two months after the transplantation. Results One month after transplantation, graft survival rate was higher in Group injected fresh autologous fat particles than that of Group injected autologous fat particles stored under 80 ℃ and Group injected autologous fat particles stored under 196 ℃ (P<0.05); Two months after transplantation, the differences among three groups had no statistical significance. Before the transplantation, the activity of autologous fat particles stored in 80 ℃ and 196 ℃ were 68.7% and 62.5% of fresh autologous fat particles, respectively, two months after cryopreservation. One month after the transplantation, we found that the activities of autologous fat particles were higher in fresh group than that of 196 ℃ and 80 ℃, There was no significant difference between the groups stored in 196 ℃ and 80 ℃. Two months after the transplantation, the activities of autologous fat particles were higher in fresh group than that of 196 ℃ and 80 ℃. Before transplantation, the particles of fat histology showed no significant difference among three groups. One month after transplantation, fat vacuoles and distinct inflammatory infiltration were observed in all three groups, with the group stored in 80 ℃ as the most serious affected. Two months after transplantation, fresh fat particles and Group stored in 196 ℃ showed large quantity of tightly packed intact fat cells, scattered around the central area in fat vacuoles, while Group stored in 80 ℃ still had a large quantity of fat vacuoles, but the fat vacuoles were obviously fused. Conclusions The fat stored at80 ℃ and196 ℃ could meet the needs of clinical use in the short time. The fat stored at 196 ℃ shows the best activity. The fat particles stored at196 ℃ could be used to establish better blood circulation. The heaviest inflammatory reaction occurs in the graft zone one month after fat transplantation and the decrease of transplanted particle activity is the most obvious. Key words: Rats; Cryopreservation; Cryoprotective agents; Fat granule; Cell activity
目的观察不同低温条件下脂肪颗粒在自体移植中的存活情况。方法3组成年Wistar大鼠分别注射新鲜的自体脂肪颗粒,分别在80℃和196℃下保存2个月,在移植后1个月和2个月对其体积、平行组织学检测、葡萄糖转运测量、MTT实验等数据进行比较分析。结果移植1个月后,注射新鲜自体脂肪颗粒组移植体存活率高于注射80℃保存的自体脂肪颗粒组和注射196℃保存的自体脂肪颗粒组(P<0.05);移植后2个月,三组间差异无统计学意义。移植前,80℃和196℃保存2个月后的自体脂肪颗粒活性分别为新鲜自体脂肪颗粒的68.7%和62.5%。移植1个月后,我们发现新鲜组的自体脂肪颗粒活性高于196℃和80℃,而196℃和80℃贮藏组之间无显著差异。移植2个月后,新鲜组的自体脂肪颗粒活性高于196℃和80℃组。移植前,三组间脂肪组织学颗粒无显著差异。移植后1个月,三组均可见脂肪空泡及明显的炎症浸润,其中80℃保存组影响最严重。移植2个月后,196℃保存的新鲜脂肪颗粒和组中有大量致密的完整脂肪细胞,分散在脂肪液泡中心周围,而80℃保存的组中仍有大量脂肪液泡,但脂肪液泡明显融合。结论在80℃和196℃条件下储存的脂肪能在短时间内满足临床使用的需要。196℃贮藏的脂肪活性最好。在196℃下储存的脂肪颗粒可用于建立良好的血液循环。脂肪移植后1个月移植区炎症反应最重,移植颗粒活性下降最明显。关键词:大鼠;低温贮藏;防冷冻的代理;脂肪粒;细胞活性
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引用次数: 0
Influence of varying intensities of water-jet force on autologous fat draft viability: an in-vitro study 不同强度水射流力对自体脂肪吸出活力的影响:体外研究
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.010
Rongrong Wang, Jiaming Sun, Jie Yang, Ke Guo
Objective To observe the effect of varying intensities of water-jet force on autologous fat graft viability. Methods Lipoaspirate was taken from 12 female patients undergoing water-jet assisted abdominal liposuction at our department. According to the intensity of water-jet force, the experimental group was divided into four subgroups: R1 (pressure, 30 bar), R2 (pressure, 50 bar), R3 (pressure, 70 bar) and R4 (pressure, 90 bar). Hand-held suction was taken as the control group C. Adipose tissue was filtered with cotton cushion and centrifuged at low speed, and the composition ratio of water and fat tissue from each group was observed. Calcein-AM/Hoechst 33342 staining was used to detect the viability of adipocytes. Results Fat aspirates was divided into four layers: oil layer, pure fat tissue, liquid and bottom sediment. Oil ratios of R1, R2, R3, R4 and C were (8.9±2.3)%, (9.6±2.1)%, (10.3±1.3)%, (14.2±1.6)% and (9.5±1.8)%, respectively. There was no statistically significant difference between R1, R2, R3 and C (P>0. 05). Statistically significant difference was found between R4 and other groups (P 0.05). Statistically significant difference was found between R3, R4 and C (P<0.05). Conclusions Viability of fat graft harvested under lower intensity of water-jet force (R1, R2) is higher than that harvested under higher intensity of water-jet force (R3, R4). Key words: Breast Beauty; Transplantation; Abdominal fat; Water-jet system; Calcein-AM/Hoechst 33342 staining; Intensity of water-jet force
目的观察不同强度的水射流力对自体脂肪移植物存活率的影响。方法对12例在我科行水射流辅助腹部抽脂术的女性患者进行抽脂。根据水射流力的强弱将实验组分为4个亚组:R1(压力,30 bar)、R2(压力,50 bar)、R3(压力,70 bar)和R4(压力,90 bar)。c组采用手持抽吸作为对照组,棉垫过滤脂肪组织,低速离心,观察各组水脂肪组织组成比。Calcein-AM/Hoechst 33342染色检测脂肪细胞活力。结果抽吸脂肪分为油层、纯脂肪组织、液体和底泥四层。石油的比率R1、R2、R3、R4和C(8.9±2.3)%,(9.6±2.1)%,(10.3±1.3)%,(14.2±1.6)%和(9.5±1.8)%,分别。R1、R2、R3与C (P < 0.05)之间差异无统计学意义。05)。R4组与其他组比较,差异有统计学意义(p0.05)。R3、R4、C之间差异有统计学意义(P<0.05)。结论低强度水射流(R1, R2)下脂肪移植体存活率高于高强度水射流(R3, R4)下脂肪移植体存活率。关键词:乳房美容;移植;腹部脂肪;喷水系统;Calcein-AM/Hoechst 33342染色;水射流力强度
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引用次数: 0
Clinical application of irradiated homograft costal cartilage granule transplantation for the pyriform aperture sunken and deformity in the facial contour 放射性同种异体肋软骨颗粒移植治疗面部梨状孔凹陷畸形的临床应用
Pub Date : 2019-10-15 DOI: 10.3760/CMA.J.ISSN.1671-0290.2019.05.019
Y. Ran, C. Jin, Xie Yang-chun, Lin Youbiao
Objective To explore the clinical application of irradiated homograft costal cartilage (IHCC) granule transplantation for the pyriform aperture sunken and deformity in the facial contour. Methods From August 2016 to November 2017, a total of 29 female patients were received IHCC transplantation to the face contour. The standardized photos were taken before and after the operation and then survey of patient satisfaction was conducted. Results In a total of 29 patients, the postoperative 21 patients were satisfied with the IHCC transplantation. After the operation, 5 cases were slightly highlighted and obvious bundles could be touched in the deep. At the early stage of operation, the cartilage particles were smoothed by means of manipulation. 3 cases were not satisfied with full effect postoperatively and satisfied after secondary transplantation. Conclusions The IHCC granule transplantation for pyriform aperture sunken and deformity can increase the overall sense of facial coordination and anti-aging, and is a safe and effective treatment. Key words: Costal cartilage; Allografts; Irradiated homograft costal cartilage; Face contour; Pyriform aperturesunken deformity
目的探讨辐照同种异体肋软骨颗粒移植治疗面部梨状孔凹陷畸形的临床应用。方法自2016年8月至2017年11月,共有29名女性患者接受了面部轮廓IHCC移植。在手术前后拍摄标准化照片,然后进行患者满意度调查。结果29例患者中,术后21例患者对IHCC移植满意。术后5例轻微突出,深部可触及明显束。在手术的早期阶段,通过手法将软骨颗粒弄平。3例术后效果不满意,二次移植后效果满意。结论IHCC颗粒移植治疗梨状孔凹陷畸形,可提高面部整体协调感和抗衰老能力,是一种安全有效的治疗方法。关键词:肋软骨;同种异体移植物;辐照同种异体移植物肋软骨;面部轮廓;梨形孔凹陷畸形
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引用次数: 0
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中华医学美学美容杂志
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