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Pancreatic Necrosectomy Through a Novel Double-flange Lumen-apposing Covered Metal Stent (Video) 新型双法兰腔旁置金属支架胰腺坏死切除术(视频)
Pub Date : 2014-12-01 DOI: 10.1016/j.vjgien.2014.10.001
Andres Sanchez-Yague, Angel Gonzalez-Canoniga, Cristina Lopez-Muñoz, Andres M. Sanchez-Cantos

Pancreatic fluid collections (PFCs) represent a complication of acute pancreatitis. Endoscopic management of PFCs is an alternative to surgery [1]. Classic strategies include access to the collection under endoscopic ultrasound (EUS)-guidance and placement of several double-pigtail stents. PFCs containing organized necrosis are classified as walled-off necrosis (WON). In those cases necrosis is hardly evacuated and will require necrosectomy in most cases. Every necrosectomy session needs prior removal of the stents, dilatation of the tract, debridement and placement of new stents adding up a considerable overall cost to the intervention. A novel double-flanged lumen-apposing fully-covered self-expandable metal stent (FC-SEMS) with a 15 mm diameter accelerates exit of the necrosis and facilitates multiple necrosectomy sessions.

We present a 60 year old patient admitted to the intensive care unit for severe acute pancreatitis that developed WON with superinfection. The intensivists and surgeons indicated endoscopic cystgastrostomy to evacuate the collection. Using the echoendoscope we found a large collection adherent to the gastric wall. The collection was accessed under EUS-guidance using the Hot AXIOS catheter that features a cautery tip, then a 15 mm AXIOS stent was deployed through the cystgastrostomy orifice to keep it patent. The patient required two necrosectomy sessions to clean the cavity. The WON resolved in 6 weeks and the stent was removed unevently. The patient was discharged.

A double flange lumen apposing FC-SEMS used as a port for necrosectomy significantly improves management of walled-off pancreatic necrosis. Placement of this stents should be considered when multiple necrosectomy sessions are anticipated. Procedure time can be significantly decreased using a catheter that combines a cautery tip and stent delivery system.

胰液收集(pfc)是急性胰腺炎的并发症。pfc的内镜治疗是手术治疗的另一种选择。经典的策略包括在超声内镜(EUS)引导下进入收集,并放置几个双尾状支架。含有组织性坏死的pfc被归类为壁闭塞性坏死(WON)。在这些情况下,坏死很难排出,大多数情况下需要进行坏死切除术。每次坏死切除术都需要事先取出支架、扩张导管、清创和放置新支架,这增加了干预的总成本。一种新型的直径为15mm的双法兰腔内全覆盖自膨胀金属支架(FC-SEMS)加速了坏死的排出,并促进了多次坏死切除术。我们提出一个60岁的病人入院重症监护病房严重急性胰腺炎,发展成WON与重复感染。重症监护医师和外科医生建议进行内窥镜膀胱胃造口术以排出收集物。在超声内镜下,我们发现附着在胃壁上的大量集合。在eus引导下,使用具有烧灼尖端的Hot AXIOS™导管访问收集,然后通过囊胃造口部署15 mm AXIOS™支架以保持其专利。患者需要两次坏死切除术来清理腔体。6周内WON消失,支架平稳取出。病人出院了。双法兰管腔毗邻FC-SEMS用作坏死切除术的端口,可显着改善对壁闭塞性胰腺坏死的管理。当预期进行多次坏死切除术时,应考虑放置这种支架。使用结合烧灼尖端和支架输送系统的导管可以显著缩短手术时间。
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引用次数: 2
Ampullary Pyloric Gland Adenoma with High-grade Dysplasia (Video) 壶腹幽门腺腺瘤伴高度不典型增生(视频)
Pub Date : 2014-12-01 DOI: 10.1016/j.vjgien.2015.03.001
Shou-jiang Tang , Ruonan Wu , William P. Daley

Background

Ampullary adenoma can be incidental or syndromic and is generally tubular, villous, or tubulovillous in histology. Pyloric gland adenoma (PGA) is uncommon, especially at extra-gastric locations.

Patient & methods

In this video manuscript, we present a case of 2 cm ampullary PGA with high-grade dysplasia (HGD), its endoscopic features, and endoscopic ampullectomy for complete resection.

Results

Under endoscopy, this ampullary PGA displayed a smooth mucosal surface with minimal pit patterns, unlike those pit patterns observed in tubular and villous adenomas. Pathologically, there was complete excision of PGA with HGD. The MUC6 immunostaining performed was positive, confirming the diagnosis of PGA.

Conclusions

Endoscopists and pathologists should be aware of PGA. Endoscopic resection should be performed for complete removal.

背景:腹部腺瘤可以是偶发的,也可以是综合征性的,在组织学上通常为管状、绒毛状或管状绒毛状。幽门腺腺瘤(PGA)是罕见的,特别是在胃外位置。病人,方法在这篇视频手稿中,我们报告了一个2厘米壶腹PGA伴高度不典型增生(HGD)的病例,其内镜特征,以及内镜下壶腹切除术以完全切除。结果内镜下,与管状和绒毛状腺瘤不同,壶腹PGA粘膜表面光滑,有少量凹痕。病理上,PGA与HGD完全切除。MUC6免疫染色阳性,证实PGA的诊断。结论内镜医师和病理学家应注意PGA。为了完全切除,应进行内镜切除。
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引用次数: 0
Underwater Endoscopic Mucosal Resection of Large Duodenal Adenomas (Video) 水下内镜下十二指肠大腺瘤粘膜切除术(视频)
Pub Date : 2014-12-01 DOI: 10.1016/j.vjgien.2015.02.002
Mary M. Flynn, Andrew Y. Wang

Background and aims

Endoscopic mucosal resection (EMR) is a well-established method for the removal of neoplastic polyps throughout the GI tract. EMR typically involves insufflation of the lumen using air or CO2, followed by submucosal lifting of a polyp to minimize the risk of deep tissue injury and perforation, followed by hot-snare polypectomy. Underwater endoscopic mucosal resection (UEMR) is a new technique that uses water to enable lesion visualization in a lumen that is not distended by air or CO2, followed by piecemeal hot-snare resection of large mucosally-based neoplasms. UEMR does not require submucosal injection to create a fluid cushion. Very few published examples of UMER in the duodenum exist. This video case series describes the use of UEMR for the resection of several large duodenal adenomas.

Procedure

Underwater endoscopic mucosal resection was utilized for the removal of several large duodenal adenomas.

Results

Three duodenal lesions ranging from 1.8 cm to 5 cm were successfully resected by UEMR. The mean time for resection was 18 min. There were no adverse events.

Conclusions

UEMR is an efficacious technique for the resection of large mucosally-based neoplasms of the duodenum.

背景和目的内镜下粘膜切除术(EMR)是一种成熟的方法,用于切除整个胃肠道的肿瘤息肉。EMR通常包括使用空气或CO2向腔内充气,然后在粘膜下提起息肉以尽量减少深部组织损伤和穿孔的风险,然后进行热陷阱息肉切除术。水下内镜粘膜切除术(UEMR)是一项新技术,它利用水在不被空气或二氧化碳扩张的腔内显示病变,然后对大型粘膜肿瘤进行分段热阱切除术。UEMR不需要粘膜下注射来产生液体垫。很少有已发表的十二指肠UMER的例子存在。本视频病例系列描述了使用UEMR切除几个大的十二指肠腺瘤。手术方法:采用水下内镜粘膜切除术切除十二指肠大腺瘤。结果UEMR成功切除3个直径为1.8 cm ~ 5 cm的十二指肠病变。平均切除时间为18分钟,无不良事件发生。结论超声磁共振是一种有效的十二指肠粘膜肿瘤切除术方法。
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引用次数: 6
Esophageal Granular Cell (Abrikossow) Tumor: Macroscopic Appearance and Endoscopic Management (Video) 食管颗粒细胞(Abrikossow)肿瘤:宏观表现和内镜治疗(视频)
Pub Date : 2014-12-01 DOI: 10.1016/j.vjgien.2015.02.001
Volker Meves, Jürgen Pohl

Granular cell tumors are rare but benign submucosal tumors of the esophagus. Usually tumors are rather small and do not cause symptoms. We demonstrate a case with typical macroscopic appearance at endoscopy and endosonography. Important differential diagnoses are leiomyoma, and gastrointestinal stroma tumors. Although the patient had no symptoms, he insisted on a complete removal of this tumor. After careful inspection of the submucosal tumor with high-definition white light endoscopy and endosonography we performed endoscopic resection. No post-procedural complications were observed.

颗粒细胞瘤是一种少见的良性食管粘膜下肿瘤。通常肿瘤很小,不会引起症状。我们报告一个在内窥镜和超声检查下具有典型宏观外观的病例。重要的鉴别诊断是平滑肌瘤和胃肠道间质瘤。虽然病人没有任何症状,但他坚持要完全切除这个肿瘤。在高清晰度白光内镜和超声检查仔细检查粘膜下肿瘤后,我们进行了内镜切除。无术后并发症。
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引用次数: 0
Gastrointestinal Sarcoidosis and Gastric Melanosis (Video) 胃肠道结节病和胃黑素病(视频)
Pub Date : 2014-12-01 DOI: 10.1016/j.vjgien.2014.11.001
Shou-jiang Tang , Ruonan Wu , Feriyl Bhaijee

Background

Sarcoidosis is a multisystem non-caseating granulomatous disease, which commonly affects the skin, joints, heart, and nervous system. Gastrointestinal sarcoidosis is rare. Likewise, only a few cases of gastric melanosis and pseudomelanosis have been reported.

Patient and methods

In this video manuscript, the authors demonstrate endoscopic and pathological findings of gastrointestinal sarcoidosis and gastric melanosis in a 53-year-old African American woman with known systemic sarcoidosis who presented with recurrent gastrointestinal bleeding.

Conclusions

Internists and gastroenterologists need to be aware of potential gastrointestinal involvement in patients with sarcoidosis. Gastric melanosis is very rare and has unknown clinical significance or implications.

结节病是一种多系统非干酪化肉芽肿性疾病,通常影响皮肤、关节、心脏和神经系统。胃肠结节病是罕见的。同样,只有少数病例的胃黑素病和假黑素病已被报道。患者和方法在这篇视频手稿中,作者展示了一名53岁非洲裔美国女性的胃肠道结节病和胃黑素病的内镜和病理结果,她患有系统性结节病,并表现为复发性胃肠道出血。结论内科医生和胃肠病学家应注意结节病患者可能累及胃肠道。胃黑素病是一种非常罕见的疾病,其临床意义和意义尚不清楚。
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引用次数: 2
Percutaneous Endoscopic Gastrostomy Tube Replacement 经皮内镜胃造口管置换术
Pub Date : 2014-09-01 DOI: 10.1016/j.vjgien.2014.01.002
Shou-jiang Tang

Background

Enteral feeding should be considered for patients with an intact and functional gastrointestinal tract. Percutaneous endoscopic gastrostomy (PEG) tube placement is indicated in patients requiring medium to long term enteral feeding (>30 days) and with impaired swallowing. Previously placed PEG tube can dislodge or be inadvertently removed, blocked, or damaged. Gastrostomy tube replacement is not infrequently performed.

Patients and methods

In this video manuscript, the author demonstrates step-by-step PEG tube replacement in several clinical scenarios: standard gastrostomy feeding tube (with internal retention balloon or with internal collapsible bumper) removal and replacement; low-profile feeding tube replacement; and feeding tube replacement over a wire guide.

Conclusions

PEG tube replacement can be easily replaced at bed-side in most cases. Occasionally, in difficult cases gastrostomy feeding tube replacement needs endoscopic guidance and assistance.

背景:对于胃肠道功能完好的患者,应考虑肠内喂养。经皮内镜胃造口术(PEG)插管适用于需要中长期肠内喂养(30天)和吞咽障碍的患者。先前放置的PEG管可能会移位或被无意中移除,阻塞或损坏。胃造口管置换并不罕见。患者和方法在这篇视频手稿中,作者演示了在几种临床情况下逐步更换PEG管:标准胃造口喂养管(带有内部保留球囊或内部可折叠缓冲器)的取出和更换;低档进料管更换;用导丝器替换饲管。结论绝大多数病例均可方便地在床边更换speg管。偶尔,在困难的情况下,胃造口喂养管更换需要内镜指导和协助。
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引用次数: 0
Features of Chronic Pancreatitis – A Focus on ERP 慢性胰腺炎的特征——以ERP为重点
Pub Date : 2014-09-01 DOI: 10.1016/j.vjgien.2014.05.001
Jörg Albert

Endoscopic retrograde cholangiopancreatography (ERCP) offers an effective interventional option for treating symptomatic chronic pancreatitis. Endoscopic pancreatic sphincterotomy is performed to facilitated endoscopic treatment. Pancreatic duct strictures can be treated by inserting plastic stents, and a 10 Fr endoprosthesis is adequate in many cases. Before stent insertion, hydrostatic balloon dilation is needed in some cases. Pancreatic stones can be removed with a dormia basket, but combining ERCP and extracorporeal shockwave lithotripsy (ESWL) is often most effective.

Standard and advanced endoscopic treatment approaches are delineated in this article and include stricture dilation with a Soehendra retriever, cSEMS placement and multi-stenting.

内镜逆行胰胆管造影(ERCP)为治疗症状性慢性胰腺炎提供了一种有效的介入选择。内镜胰括约肌切开术以方便内镜治疗。胰管狭窄可以通过植入塑料支架来治疗,在许多情况下,10fr内假体就足够了。在某些情况下,在支架置入之前,需要进行静压球囊扩张。胰脏结石可以用睡眠篮去除,但ERCP和体外冲击波碎石术(ESWL)相结合通常是最有效的。本文描述了标准和先进的内镜治疗方法,包括使用Soehendra检索器进行狭窄扩张,cems放置和多支架置入。
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引用次数: 0
Safe Endoscopic Removal of a Migrated Esophageal Stent Using a Protection Hood 内镜下使用保护罩安全移除移位的食管支架
Pub Date : 2014-09-01 DOI: 10.1016/j.vjgien.2014.06.001
Marta Serrani, Liza Ceroni, Pietro Fusaroli, M. Cristina D’Ercole, Giancarlo Caletti

Delayed esophageal metallic stent migration after a neo-adjuvant therapy of advanced esophageal cancer is a relatively frequent event, which is sometimes due to tumor response to chemotherapy.

Stent migration in the stomach is usually asymptomatic but it can cause potentially life-threatening complications as bowel obstruction or perforation.

Most gastric migrations can be managed endoscopically; however endoscopic stent removal could also be a risky procedure due to hemorrhage or esophageal perforation.

This case report describes a safe and quick endoscopic method to remove a migrated esophageal metallic stent from the stomach using a protection hood mounted on the tip of the endoscope.

晚期食管癌新辅助治疗后食管金属支架延迟移位是一个相对常见的事件,有时是由于肿瘤对化疗的反应。胃内支架移动通常是无症状的,但它可能导致潜在的危及生命的并发症,如肠梗阻或穿孔。大多数胃迁移可以在内镜下处理;然而,由于出血或食管穿孔,内镜下支架移除也可能是一个危险的过程。本病例报告描述了一种安全快速的内窥镜方法,使用安装在内窥镜尖端的保护罩从胃中取出移位的食管金属支架。
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引用次数: 0
Features of Chronic Pancreatitis and Associated Masses: A Focus on Endosonography 慢性胰腺炎及相关肿块的特征:超声检查的重点
Pub Date : 2014-09-01 DOI: 10.1016/j.vjgien.2014.07.001
Bronte A. Holt, Shyam Varadarajulu

EUS is highly accurate in the diagnosis of chronic pancreatitis. Pancreatic calcifications or five or more endosonographic criteria are consistent with chronic pancreatitis. Less than three criteria essentially rules out chronic pancreatitis. Three or four criteria are the best overall cutoffs. The number of criteria is used to estimate the likelihood of pancreatitis (i.e. low/medium/high), and is not recommended to stage the severity (i.e. mild/moderate/severe) of disease. Obtaining histology by FNA is not recommended in all patients with chronic pancreatitis changes. EUS is useful in distinguishing inflammatory from malignant masses in the pancreas. FNA is often not required as the EUS appearance of inflammatory changes alone or bulkiness without any perceptible mass has good negative predictive value. In indeterminate masses, FNA for cytology is recommended. Follow-up imaging after one to two months can be performed to catch the rare EUS false-negatives, and confirm resolution or stability of inflammatory masses.

EUS对慢性胰腺炎的诊断具有很高的准确性。胰腺钙化或5项及以上超声检查标准符合慢性胰腺炎。少于三个标准基本上可以排除慢性胰腺炎。三到四个标准是最好的总体分界点。标准的数量用于估计胰腺炎的可能性(即低/中/高),不建议对疾病的严重程度(即轻度/中度/严重)进行分级。不推荐所有有慢性胰腺炎改变的患者通过FNA获取组织学。EUS有助于区分胰腺的炎性肿块和恶性肿块。通常不需要FNA,因为EUS表现仅为炎症改变或未见肿块的肿大具有良好的阴性预测价值。对于不确定的肿块,建议采用FNA细胞学检查。随访1 ~ 2个月后可进行影像学检查,以发现罕见的EUS假阴性,并确认炎性肿块的消退或稳定性。
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引用次数: 4
Endoscopic Removal of an Impacted Needle with Syringe from the Esophagus 内镜下用注射器从食道取出阻生针
Pub Date : 2014-09-01 DOI: 10.1016/j.vjgien.2014.08.001
Shou-jiang Tang , Indu Srinivasan , Jason H. Williams , Anson L. Thaggard

Background

In adults, non-food foreign body ingestions occur more in denture users, incarcerated individuals, and in patients with psychiatric disorders or alcohol intoxication. The majority of the ingested foreign body will pass spontaneously. Sharp or pointed foreign body, animal or fish bones, and magnets increase the risk of perforation.

Patient

An incarcerated patient with bipolar disorder swallowed a 14 cm in length needle attached with a syringe three months prior to presentation. The needle penetrated the distal esophagus leading to mediastinitis.

Methods

In this video manuscript, we demonstrated endoscopic techniques on how to remove this 14 cm long sharp object.

Results

The foreign body was removed uneventfully and mediastinitis resolved with antibiotic treatment.

Conclusions

Emergent endoscopy is indicated in (1) esophageal obstruction and the patient are unable to swallow secretions and (2) disk batteries and sharp-pointed foreign body in the esophagus.

在成年人中,非食物异物摄入更多发生在假牙使用者、监禁者、精神障碍或酒精中毒患者中。大部分被摄入的异物会自行排出。尖锐的异物、动物或鱼骨、磁铁会增加穿孔的风险。患者:一位被监禁的双相情感障碍患者在就诊前三个月吞下了一根长14厘米的针,针上附有注射器。针穿入食管远端导致纵隔炎。方法在本视频手稿中,我们演示了内窥镜技术如何去除这个14厘米长的尖锐物体。结果异物顺利取出,纵隔炎经抗生素治疗痊愈。结论:(1)食管梗阻,患者不能吞咽分泌物;(2)食管内有盘状电池及尖锐异物,需急诊内镜检查。
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引用次数: 0
期刊
Video Journal and Encyclopedia of GI Endoscopy
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