首页 > 最新文献

Harefuah最新文献

英文 中文
[LACERTUS SYNDROME].
Pub Date : 2025-02-01
Ruth Fann Marko, Gershon Zinger, Ayman Khoury

Introduction: Lacertus syndrome is a relatively rare condition that occurs because of median nerve compression at the elbow. Despite its low prevalence, it is important for healthcare professionals to be aware of this condition and its potential symptoms to provide timely and accurate diagnosis and treatment. This review provides a comprehensive overview of lacertus syndrome, including its anatomy and physiology, symptoms, and challenges of diagnosis. In particular, the article highlights the potential for misdiagnosis as carpal tunnel syndrome or other conditions that affect the median nerve and provides guidance on the physical exam and other diagnostic tests that can be used to confirm the diagnosis. The available treatment options for lacertus syndrome are also discussed, including conservative measures such as rest, activity modification and physical therapy, as well as more invasive options such as surgery. Finally, the article concludes with recommendations for future research and practice in the area of lacertus syndrome, highlighting the need for continued education and awareness among healthcare professionals.

简介拉塞尔特斯综合征是一种相对罕见的疾病,是由于肘部正中神经受压而引起的。尽管发病率较低,但医护人员必须了解这种疾病及其潜在症状,以便提供及时、准确的诊断和治疗。本综述全面概述了拉克氏综合征,包括其解剖和生理学、症状和诊断难题。文章特别强调了将其误诊为腕管综合征或其他影响正中神经的疾病的可能性,并就体格检查和其他可用于确诊的诊断测试提供了指导。文章还讨论了裂隙综合征的现有治疗方案,包括休息、调整活动量和物理治疗等保守措施,以及手术等更具侵入性的治疗方案。最后,文章对腔隙综合征领域未来的研究和实践提出了建议,强调了继续教育和提高医护人员认识的必要性。
{"title":"[LACERTUS SYNDROME].","authors":"Ruth Fann Marko, Gershon Zinger, Ayman Khoury","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Lacertus syndrome is a relatively rare condition that occurs because of median nerve compression at the elbow. Despite its low prevalence, it is important for healthcare professionals to be aware of this condition and its potential symptoms to provide timely and accurate diagnosis and treatment. This review provides a comprehensive overview of lacertus syndrome, including its anatomy and physiology, symptoms, and challenges of diagnosis. In particular, the article highlights the potential for misdiagnosis as carpal tunnel syndrome or other conditions that affect the median nerve and provides guidance on the physical exam and other diagnostic tests that can be used to confirm the diagnosis. The available treatment options for lacertus syndrome are also discussed, including conservative measures such as rest, activity modification and physical therapy, as well as more invasive options such as surgery. Finally, the article concludes with recommendations for future research and practice in the area of lacertus syndrome, highlighting the need for continued education and awareness among healthcare professionals.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"96-99"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A 72 YEARS OLD WOMAN WITH A BEADED NECKLACE ON HER NECK]. [一位 72 岁的老妇人,脖子上戴着一条串珠项链]。
Pub Date : 2025-02-01
Gil Bachar

Introduction: A 72 YEARS OLD WOMAN WITH A BEADED NECKLACE ON HER NECK.

{"title":"[A 72 YEARS OLD WOMAN WITH A BEADED NECKLACE ON HER NECK].","authors":"Gil Bachar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>A 72 YEARS OLD WOMAN WITH A BEADED NECKLACE ON HER NECK.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"126-127"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[COMBINED TREATMENT OF RAPIDLY INCREASING MYOPIA: A CASE SERIES].
Pub Date : 2025-02-01
Nir Erdinest, Maya Atar Vardi, Yair Morad

Introduction: This case series demonstrates the combination of topical 0.05% atropine, wearing a peripheral defocus (MF60) contact lens, and increased outdoor activity during daylight hours to treat myopia's rapid progression in three children. It includes two boys and one girl with an average age of 12.5±0.5 years with spherical equivalent (SE) of -4.06±0.35 diopters (D) and an average axial length (AL) of 25.11±0.49 mm at the beginning of treatment. All children exhibited myopia progression the year before treatment, averaging 1.29±0.13- D SE. The children had not previously undergone myopia management treatment. Due to this rapid progression, a combination of daily instillation of 0.05% atropine and wearing a daily disposable soft contact lens of a unique design was initiated. Cycloplegic refraction was checked, and a slit-lamp examination was conducted every six months. The children's 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) score was 19.33±2.52. Over a year, the average myopia progression decreased to -0.34±0.12 diopters, and the average AL growth was 0.16±0.10 mm. This case series reports successful combined treatment for the rapid progression of myopia and a mini-review of the medical literature on the subject.

{"title":"[COMBINED TREATMENT OF RAPIDLY INCREASING MYOPIA: A CASE SERIES].","authors":"Nir Erdinest, Maya Atar Vardi, Yair Morad","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>This case series demonstrates the combination of topical 0.05% atropine, wearing a peripheral defocus (MF60) contact lens, and increased outdoor activity during daylight hours to treat myopia's rapid progression in three children. It includes two boys and one girl with an average age of 12.5±0.5 years with spherical equivalent (SE) of -4.06±0.35 diopters (D) and an average axial length (AL) of 25.11±0.49 mm at the beginning of treatment. All children exhibited myopia progression the year before treatment, averaging 1.29±0.13- D SE. The children had not previously undergone myopia management treatment. Due to this rapid progression, a combination of daily instillation of 0.05% atropine and wearing a daily disposable soft contact lens of a unique design was initiated. Cycloplegic refraction was checked, and a slit-lamp examination was conducted every six months. The children's 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) score was 19.33±2.52. Over a year, the average myopia progression decreased to -0.34±0.12 diopters, and the average AL growth was 0.16±0.10 mm. This case series reports successful combined treatment for the rapid progression of myopia and a mini-review of the medical literature on the subject.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"90-95"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[DISCOVERIES FROM THE WORLD OF CHINESE MEDICINE: TRADITIONAL SOLUTIONS FOR ROSACEA].
Pub Date : 2025-02-01
Ofir Kotek, David Perla, Aviv Barzilai, Sharon Baum

Introduction: Rosacea is a chronic inflammatory skin disease that affects mostly the facial skin. Possible symptoms include redness, papules, pustules, and changes in the nose and eyes. The cause is unknown, but may be related to diet, alcoholic drinks, demodicosis and more. Some patients seek alternatives to conventional treatments and turn to traditional Chinese medicine, which provides a holistic and alternative approach that includes treatment with medicinal herbs, acupuncture, and more.

Objectives: This article presents a 50-year-old patient suffering from severe rosacea for the past three years, without improvement using conventional treatments. The patient was then treated with Chinese medicine, resulting in significant improvement.

Conclusions: Integrating Chinese medicine into modern medical treatment can help improve the condition of rosacea patients. Further research is needed to establish evidence and prove efficacy, to allow the integration of these tools into guidelines and daily treatment.

Discussion: Rosacea patients turn to complementary therapies due to dissatisfaction and lack of progress with conventional treatments. These patients have explored various treatment paths, including complementary medicine, particularly Traditional Chinese Medicine. Insights from recent studies indicate an improvement in the condition and quality of life of rosacea patients in response to these treatments, compared to both placebo and, in some cases, even modern treatments. The trend of using these complementary therapies requires a broader understanding and evidence-based guidelines, as these treatments are considered relatively safe with minimal side effects and good tolerability.

{"title":"[DISCOVERIES FROM THE WORLD OF CHINESE MEDICINE: TRADITIONAL SOLUTIONS FOR ROSACEA].","authors":"Ofir Kotek, David Perla, Aviv Barzilai, Sharon Baum","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Rosacea is a chronic inflammatory skin disease that affects mostly the facial skin. Possible symptoms include redness, papules, pustules, and changes in the nose and eyes. The cause is unknown, but may be related to diet, alcoholic drinks, demodicosis and more. Some patients seek alternatives to conventional treatments and turn to traditional Chinese medicine, which provides a holistic and alternative approach that includes treatment with medicinal herbs, acupuncture, and more.</p><p><strong>Objectives: </strong>This article presents a 50-year-old patient suffering from severe rosacea for the past three years, without improvement using conventional treatments. The patient was then treated with Chinese medicine, resulting in significant improvement.</p><p><strong>Conclusions: </strong>Integrating Chinese medicine into modern medical treatment can help improve the condition of rosacea patients. Further research is needed to establish evidence and prove efficacy, to allow the integration of these tools into guidelines and daily treatment.</p><p><strong>Discussion: </strong>Rosacea patients turn to complementary therapies due to dissatisfaction and lack of progress with conventional treatments. These patients have explored various treatment paths, including complementary medicine, particularly Traditional Chinese Medicine. Insights from recent studies indicate an improvement in the condition and quality of life of rosacea patients in response to these treatments, compared to both placebo and, in some cases, even modern treatments. The trend of using these complementary therapies requires a broader understanding and evidence-based guidelines, as these treatments are considered relatively safe with minimal side effects and good tolerability.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"82-86"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[STARVING OUR HOSTAGES IN HAMAS CAPTIVITY].
Pub Date : 2025-02-01
Gad Keren

Introduction: STARVING OUR HOSTAGES IN HAMAS CAPTIVITY.

{"title":"[STARVING OUR HOSTAGES IN HAMAS CAPTIVITY].","authors":"Gad Keren","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>STARVING OUR HOSTAGES IN HAMAS CAPTIVITY.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"72-73"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[CONGENITAL TOXOPLASMOSIS: AWARENESS ENABLES PREVENTION, EARLY TREATMENT, AND IMPROVED OUTCOME].
Pub Date : 2025-02-01
Lia Schoenfeld, Liat Gindes, Tally Lerman-Sagie

Introduction: Infection with the intracellular parasite Toxoplasma gondii is a common worldwide infection and is often asymptomatic. A unique risk group that requires identification of such infection is fetuses, and the earlier the infection, the more severe the damage. As pregnancy progresses, the risk of fetal infection increases. The parasite causes inflammatory processes in the placenta, fetal brain, eyes, and heart. The range of damage includes miscarriages, neurological and psychiatric disorders, hearing impairment, visual impairment, and cardiovascular disorders. In order to reduce the incidence of toxoplasmosis in children, awareness and preventive measures are required. Primary prevention is carried out by hand hygiene and avoiding certain foods. Secondary prevention is carried out by early detection through serological screening tests, and tertiary prevention is carried out by early treatment of mothers who have been infected with the parasite, or by testing newborns, who may be asymptomatic at birth but can still develop serious illness. It has been found that in Israel, the relative rate of severe clinical manifestations in children is higher than in European countries. The combination of risk groups, the lack of screening tests for pregnant women, and the lack of appropriate treatment can explain this observation. The aim of this review is to raise awareness of congenital toxoplasmosis and the possibilities of prevention and reduction of harm to fetuses and children. It also provides up-to-date information and recommendations for policy change.

{"title":"[CONGENITAL TOXOPLASMOSIS: AWARENESS ENABLES PREVENTION, EARLY TREATMENT, AND IMPROVED OUTCOME].","authors":"Lia Schoenfeld, Liat Gindes, Tally Lerman-Sagie","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Infection with the intracellular parasite Toxoplasma gondii is a common worldwide infection and is often asymptomatic. A unique risk group that requires identification of such infection is fetuses, and the earlier the infection, the more severe the damage. As pregnancy progresses, the risk of fetal infection increases. The parasite causes inflammatory processes in the placenta, fetal brain, eyes, and heart. The range of damage includes miscarriages, neurological and psychiatric disorders, hearing impairment, visual impairment, and cardiovascular disorders. In order to reduce the incidence of toxoplasmosis in children, awareness and preventive measures are required. Primary prevention is carried out by hand hygiene and avoiding certain foods. Secondary prevention is carried out by early detection through serological screening tests, and tertiary prevention is carried out by early treatment of mothers who have been infected with the parasite, or by testing newborns, who may be asymptomatic at birth but can still develop serious illness. It has been found that in Israel, the relative rate of severe clinical manifestations in children is higher than in European countries. The combination of risk groups, the lack of screening tests for pregnant women, and the lack of appropriate treatment can explain this observation. The aim of this review is to raise awareness of congenital toxoplasmosis and the possibilities of prevention and reduction of harm to fetuses and children. It also provides up-to-date information and recommendations for policy change.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"114-118"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[PREGNANCY AND OBESITY - PREVENTION OF OBESITY IN THE NEXT GENERATION]. [怀孕与肥胖--预防下一代肥胖]。
Pub Date : 2025-02-01
Sofia Soltsman, Izhar Ben Shlomo

Introduction: Obesity is a feature affecting nearly all life aspects. As the burden of obesity is increasing steadily, it leads to the increasing prevalence of diabetes, and most other common non-communicable diseases. A comprehensive approach for the prevention of obesity appears to constitute the most effective intervention to reduce their prevalence worldwide. In this review, we highlight pregnancy as a key period in a woman's life, which can improve compliance with different types of diet, physical activity, and behavioural programs, affecting the next generation's health, and breaking the vicious cycle of family obesity.

{"title":"[PREGNANCY AND OBESITY - PREVENTION OF OBESITY IN THE NEXT GENERATION].","authors":"Sofia Soltsman, Izhar Ben Shlomo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity is a feature affecting nearly all life aspects. As the burden of obesity is increasing steadily, it leads to the increasing prevalence of diabetes, and most other common non-communicable diseases. A comprehensive approach for the prevention of obesity appears to constitute the most effective intervention to reduce their prevalence worldwide. In this review, we highlight pregnancy as a key period in a woman's life, which can improve compliance with different types of diet, physical activity, and behavioural programs, affecting the next generation's health, and breaking the vicious cycle of family obesity.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"119-123"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[PLANTAR FASCIOPATHY - DIAGNOSIS AND TREATMENT].
Pub Date : 2025-02-01
Dana Avraham, Ruslan Sokolov, Izhar Arieli, Oded Stav, Amir Herman, Maria Oulianski

Introduction: Plantar Fasciitis is a common reason for heel pain. The pain caused by structural changes in the plantar fascia aponeurosis insertion to the calcaneus bone. Risk factors include obesity, prolonged standing, dorsiflexion limited range of motion, excessive running, and pes planus or pes cavus. Diagnosis is based on the patient's history and physical examination. The patient will complain of heel pain during their first steps after sleep or prolonged rest, palpation will provoke pain on the plantar medial aspect of the calcaneus. Physicians rarely use imaging to verify the diagnosis. The use of imaging may take place in cases of intractable pain regardless of conservative treatment in order to eliminate different causes for heel pain. Conservative treatment is effective for over 90% of the patients. Patients with plantar fasciitis chronic pain for over 6 mounts may consider a Pain Clinic or planter fasciotomy surgery.

简介足底筋膜炎是足跟疼痛的常见原因。足底筋膜炎是足跟疼痛的常见原因,是由于足底筋膜肌腱插入小腿骨的结构发生变化而引起的疼痛。危险因素包括肥胖、长时间站立、背屈活动范围受限、过度跑步、扁平足或穴状足。诊断主要依据患者的病史和体格检查。患者会在睡眠或长时间休息后迈出第一步时诉说足跟疼痛,触诊会在小腿足底内侧引起疼痛。医生很少使用影像学检查来确诊。如果疼痛顽固,无论是否采取保守治疗,都可能需要进行影像学检查,以排除导致足跟痛的不同原因。保守治疗对 90% 以上的患者有效。足底筋膜炎慢性疼痛超过 6 个月的患者可考虑接受疼痛门诊或足底筋膜切开手术。
{"title":"[PLANTAR FASCIOPATHY - DIAGNOSIS AND TREATMENT].","authors":"Dana Avraham, Ruslan Sokolov, Izhar Arieli, Oded Stav, Amir Herman, Maria Oulianski","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Plantar Fasciitis is a common reason for heel pain. The pain caused by structural changes in the plantar fascia aponeurosis insertion to the calcaneus bone. Risk factors include obesity, prolonged standing, dorsiflexion limited range of motion, excessive running, and pes planus or pes cavus. Diagnosis is based on the patient's history and physical examination. The patient will complain of heel pain during their first steps after sleep or prolonged rest, palpation will provoke pain on the plantar medial aspect of the calcaneus. Physicians rarely use imaging to verify the diagnosis. The use of imaging may take place in cases of intractable pain regardless of conservative treatment in order to eliminate different causes for heel pain. Conservative treatment is effective for over 90% of the patients. Patients with plantar fasciitis chronic pain for over 6 mounts may consider a Pain Clinic or planter fasciotomy surgery.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"103-107"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[MANAGEMENT OF LABOR ANESTHESIA IN A PATIENT WITH EHLERS-DANLOS SYNDROME WHY DOES CHATGPT ERR IN SOURCE REFERENCING?]
Pub Date : 2025-02-01
Daphna Idan, Rotem Sisso-Avron, Or Degany

Introduction: Ehlers-Danlos Syndrome (EDS) encompasses a spectrum of inherited disorders, characterized by joint hypermobility, skin hyperextensibility, and other features. In some patients, EDS involves the vascular walls, posing a significant clinical challenge due to the resultant propensity for rupture with hemorrhagic complications. Such complications, among others that often occur with EDS, may carry particular importance in the context of pregnancy and labor. This paper presents a patient diagnosed with Ehlers-Danlos Syndrome during her first pregnancy. The patient was planned for elective Cesarean delivery and expressed an interest in regional anesthesia. A literature review was conducted to identify similar cases in which the anesthesia techniques and their potential complications were described, as well as additional risks for EDS patients associated with various anesthesia methods. The review identified only low-quality data, which suggested a higher pain threshold in patients with EDS and an increased risk of bleeding. This case was used to assess the ability of ChatGPT to present a literature review based on reliable sources when the evidence is sparse. The model generated a well-worded response using correct medical terminology, but the report was superficial and provided no data to support clinical decision-making. The model also suggested a different anesthetic approach than the human-generated literature review and supported its findings with links to cited sources. These sources were examined, and concerns regarding their reliability were raised. Lack of reliability remains a major challenge for developers and users of large language models. Fine-tuning (i.e. training the model with examples relevant to specific tasks) which may enhance model output accuracy is discussed in this context.

{"title":"[MANAGEMENT OF LABOR ANESTHESIA IN A PATIENT WITH EHLERS-DANLOS SYNDROME WHY DOES CHATGPT ERR IN SOURCE REFERENCING?]","authors":"Daphna Idan, Rotem Sisso-Avron, Or Degany","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Ehlers-Danlos Syndrome (EDS) encompasses a spectrum of inherited disorders, characterized by joint hypermobility, skin hyperextensibility, and other features. In some patients, EDS involves the vascular walls, posing a significant clinical challenge due to the resultant propensity for rupture with hemorrhagic complications. Such complications, among others that often occur with EDS, may carry particular importance in the context of pregnancy and labor. This paper presents a patient diagnosed with Ehlers-Danlos Syndrome during her first pregnancy. The patient was planned for elective Cesarean delivery and expressed an interest in regional anesthesia. A literature review was conducted to identify similar cases in which the anesthesia techniques and their potential complications were described, as well as additional risks for EDS patients associated with various anesthesia methods. The review identified only low-quality data, which suggested a higher pain threshold in patients with EDS and an increased risk of bleeding. This case was used to assess the ability of ChatGPT to present a literature review based on reliable sources when the evidence is sparse. The model generated a well-worded response using correct medical terminology, but the report was superficial and provided no data to support clinical decision-making. The model also suggested a different anesthetic approach than the human-generated literature review and supported its findings with links to cited sources. These sources were examined, and concerns regarding their reliability were raised. Lack of reliability remains a major challenge for developers and users of large language models. Fine-tuning (i.e. training the model with examples relevant to specific tasks) which may enhance model output accuracy is discussed in this context.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"74-76"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[THE EFFECT OF THE ISRAELI AUTHORITY PLAN TO DIVERT PRIVATE TO PUBLIC FUNDING ON THE RESULTS OF IN VITRO FERTILIZATION TREATMENT OUTCOME]. [以色列当局将私人资金转为公共资金的计划对体外受精治疗结果的影响]。
Pub Date : 2025-02-01
Raoul Orvieto, Oshrit Shtossel, Tamar Shtral, Yael Raichenberg, Ravit Nahum

Introduction: Israel's public funding policy for in vitro fertilization (IVF) is unique globally, with only minor restrictions. In late 2017, a program was launched to shift IVF treatments from private to public funding in an attempt to reduce waiting times, allowing IVF treatment in both public and private centers within the health basket.

Objectives: The study aimed to analyze the impact of this program on IVF treatment outcomes using data from the Clalit-Dan district.

Methods: Data from the Clalit-Dan District Health Insurance Fund (2014-2021) were analyzed, comparing IVF outcomes cumulative live birth rates (using Kaplan-Meier curves) in public and private centers.

Results: Between the years 2014 and 2021, 14,509 IVF treatment cycles were performed within the health basket in the Dan District. After implementing the 2017 aforementioned programe, IVF cycles in private centers increased, with no change in public centers. Live birth rates were slightly higher in public centers compared to private centers (10.02% vs. 9.04%), but without statistical significance (p=0.13). A noticeable decline in live birth rates was observed after 2018, especially in fresh cycles. No significant differences were found between public and private centers for women aged 20-39 years, but for those aged 40-45 years, public centers had significantly higher live birth rates, particularly in fresh cycles.

Conclusions: The 2017 program to shift IVF activity from private to public funding increased the burden on private centers and led to a decline in live birth rates, particularly for women over 40 years of age. The Ministry of Health, being entrusted, among other things, with the supervision and control of the IVF units in Israel, must examine and provide an adequate response to the issues raised above.

{"title":"[THE EFFECT OF THE ISRAELI AUTHORITY PLAN TO DIVERT PRIVATE TO PUBLIC FUNDING ON THE RESULTS OF IN VITRO FERTILIZATION TREATMENT OUTCOME].","authors":"Raoul Orvieto, Oshrit Shtossel, Tamar Shtral, Yael Raichenberg, Ravit Nahum","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Israel's public funding policy for in vitro fertilization (IVF) is unique globally, with only minor restrictions. In late 2017, a program was launched to shift IVF treatments from private to public funding in an attempt to reduce waiting times, allowing IVF treatment in both public and private centers within the health basket.</p><p><strong>Objectives: </strong>The study aimed to analyze the impact of this program on IVF treatment outcomes using data from the Clalit-Dan district.</p><p><strong>Methods: </strong>Data from the Clalit-Dan District Health Insurance Fund (2014-2021) were analyzed, comparing IVF outcomes cumulative live birth rates (using Kaplan-Meier curves) in public and private centers.</p><p><strong>Results: </strong>Between the years 2014 and 2021, 14,509 IVF treatment cycles were performed within the health basket in the Dan District. After implementing the 2017 aforementioned programe, IVF cycles in private centers increased, with no change in public centers. Live birth rates were slightly higher in public centers compared to private centers (10.02% vs. 9.04%), but without statistical significance (p=0.13). A noticeable decline in live birth rates was observed after 2018, especially in fresh cycles. No significant differences were found between public and private centers for women aged 20-39 years, but for those aged 40-45 years, public centers had significantly higher live birth rates, particularly in fresh cycles.</p><p><strong>Conclusions: </strong>The 2017 program to shift IVF activity from private to public funding increased the burden on private centers and led to a decline in live birth rates, particularly for women over 40 years of age. The Ministry of Health, being entrusted, among other things, with the supervision and control of the IVF units in Israel, must examine and provide an adequate response to the issues raised above.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"164 2","pages":"77-81"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Harefuah
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1