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Federalism and primary healthcare access to medicines. 联邦制和获得初级医疗保健药品的机会。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-26 DOI: 10.1590/1413-81232026311.14142025
Bábilla Nunes de Souza, Fernanda Ferreira Matos, Franciele de Matos Silva, Melina Calmon Silva, Eidy de Brito Farias, Rafael Poloni, Marco Aurélio Pereira

Public Health is a fundamental social right, and the State is responsible for ensuring universal and equitable access through public policies. This duty is shared among the Federal Government, states, the Federal District, and municipalities, which hold legislative and administrative powers to safeguard health. With the creation of the Unified Health System (SUS), comprehensive care, including pharmaceutical therapy, became a guaranteed right. Intergovernmental coordination, through agreements and fund transfers, seeks to promote equity in access to medicines in Primary Health Care. Challenges related to funding, resource distribution, and the roles of each governmental entity still spark debates among managers and researchers. This article examines the advances and perspectives in access to medicines in Primary Health Care, discussing the combination of decentralization and centralization, along with cooperation among governmental entities, and its importance in ensuring universal and comprehensive access to Brazilian health services. Intermunicipal consortia, such as the Paraná Saúde Consortium®, exemplify successful solutions for coordinating access to medicines, showing the need for flexibility in addressing regional diversity and ensuring system comprehensiveness.

公共卫生是一项基本的社会权利,国家有责任通过公共政策确保普遍和公平获得。这项责任由联邦政府、各州、联邦区和各市共同承担,它们拥有保障健康的立法和行政权力。随着统一卫生系统(SUS)的建立,包括药物治疗在内的全面护理成为一项有保障的权利。政府间协调通过协议和资金转移,力求促进初级保健中公平获得药品。与资金、资源分配和每个政府实体的角色相关的挑战仍然引发了管理人员和研究人员之间的争论。本文考察了初级卫生保健在获得药品方面的进展和前景,讨论了分权和集权的结合,以及政府实体之间的合作,以及它在确保普遍和全面获得巴西卫生服务方面的重要性。像paran Saúde联盟®这样的城市间联盟是协调药品可及性的成功解决方案的范例,表明在解决区域多样性和确保系统全面性方面需要灵活性。
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引用次数: 0
ERRATUM. 勘误表。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1590/1413-81232026311.16022025

[This corrects the article doi: 10.1590/1413-81232025307.05232023EN].

[更正文章doi: 10.1590/1413-81232025307.05232023EN]。
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引用次数: 0
What are the "best-buys" for health promotion in pharmacy? 在药房促进健康的“最合算”是什么?
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-26 DOI: 10.1590/1413-81232026311.14152025
Ruben Viegas, Romeu Mendes, Filipa Alves da Costa

Chronic non-communicable diseases (NCDs) significantly contribute to global mortality and diminished quality of life, placing a growing burden on healthcare systems. The World Health Organization has developed cost-effective strategies to manage these diseases, entitled "best buys", by addressing major risk factors for NCDs, such as smoking, alcohol use, unhealthy diets, and physical inactivity. Pharmacies, as accessible healthcare facilities, are well-positioned to support preventive care and behaviour change, including tobacco and alcohol cessation, dietary modifications, and physical activity promotion. Legislation in some countries, like Portugal, empowers pharmacies to deliver health promotion services to the communities they serve. Strengthening collaboration between pharmacies, other healthcare services, and public health authorities can amplify the impact of these initiatives, improving population health outcomes.

慢性非传染性疾病(NCDs)严重导致全球死亡率和生活质量下降,给卫生保健系统带来越来越大的负担。世界卫生组织制定了具有成本效益的战略,通过解决非传染性疾病的主要风险因素,如吸烟、饮酒、不健康饮食和缺乏身体活动,来管理这些疾病,称为“最合算”。药店作为无障碍的卫生保健设施,在支持预防保健和行为改变,包括戒烟和戒酒、调整饮食和促进体育活动方面处于有利地位。一些国家,如葡萄牙,立法授权药店向其所服务的社区提供健康促进服务。加强药房、其他卫生保健服务机构和公共卫生当局之间的合作,可以扩大这些举措的影响,改善人口健康结果。
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引用次数: 0
Stork Network in Pernambuco, Brazil: an overview of SUS auditing in the evaluation of prenatal care. 鹳网络在伯南布哥,巴西:在产前护理评估SUS审计的概述。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2024-11-04 DOI: 10.1590/1413-81232026311.10372024
Vania Nazaré da Costa Silva, Daphne Rattner, Rosamaria Giatti Carneiro, Antonio Flaudiano Bem Leite

The Stork Network (SN) strategy was created to guarantee comprehensive care and address high maternal and infant mortality rates. The aim of this study was to assess the actions developed by the SN across municipalities in the state Pernambuco and the association between these actions and prenatal care quality indicators. We conducted a multi-group ecological study of Component I of the SN in Pernambuco using data from audits conducted under the state component of the National Audit System for the period 2017 to 2020. We explored the association between ten actions and the prenatal care quality indicators. The indicators with the highest ratings were "improved access to high-risk prenatal care", "rapid syphilis/HIV testing" and "laboratory testing for low and high risk pregnant women". The indicator with the strongest association to mean congenital syphilis rate was rapid testing for syphilis/HIV. Two indicators showed a statistically significant association with mean perinatal mortality rate: "improved access to high-risk prenatal care" and "support for travel". We conclude that the organizational management of the SN in Pernambuco and provision of services under component I did not meet the objectives of strategy. Our findings demonstrate the potential of auditing for supporting policy implementation.

制定鹳网络战略是为了保证全面护理和解决产妇和婴儿死亡率高的问题。本研究的目的是评估全国产前护理协会在伯南布哥州各城市开展的行动,以及这些行动与产前护理质量指标之间的关系。我们利用2017年至2020年期间在国家审计系统的州组成部分进行的审计数据,对伯南布哥州的SN组成部分进行了多组生态研究。我们探讨了十项行动与产前护理质量指标之间的关系。评分最高的指标是“改善获得高风险产前护理的机会”、“快速梅毒/艾滋病毒检测”和“对低风险和高风险孕妇进行实验室检测”。与先天性梅毒发病率相关性最强的指标是梅毒/HIV快速检测。有两项指标与平均围产期死亡率有显著的统计关联:“改善获得高风险产前护理的机会”和“旅行支助”。我们的结论是,伯南布哥州SN的组织管理和在组成部分I下提供的服务不符合战略目标。我们的研究结果证明了审计在支持政策实施方面的潜力。
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引用次数: 0
Availability of basic component medicines recommended in the PCDT in municipal lists of essential medicines. 城市基本药物清单中PCDT建议的基本成分药物的可获得性。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-30 DOI: 10.1590/1413-81232026311.14242025
Beatriz de Toledo Minguzzi, Adriane Lopes Medeiros Simone, Bruna Bento Dos Santos, Daniela Oliveira de Melo

The integrality of care is one of the core principles of the National Policy of Pharmaceutical Assistance (Política Nacional de Assistência Farmacêutica - PNAF) and underpins two tools that guide the use of medicines: clinical protocols and therapeutic guidelines (protocolos clínicos e diretrizes terapêuticas - PCDT) and the lists of essential medicines. municipalities are encouraged to use these for healthcare management, but the development of municipal lists (relações municipais de medicamentos essenciais - Remume) presents weak points. The aim is to describe potential impacts on the implementation of PCDT from the perspective of the unavailability of medicines from the Basic Component of Pharmaceutical Assistance (Componente Básico da Assistência Farmacêutica - CBAF) in Remume. The CBAF medicines included in the PCDT until June 2023 were extracted. Forty-eight municipalities were selected for the Remume search and verification of the medicines of interest. Each PCDT was analyzed according to the lack of the least found medicines. The Remume contained, on average, 60% (44-75%) of the listed medicines, and the average coverage of each PCDT ranged from 2% to 100%. Of 62, 11 PCDT were impacted by the low availability of medicines. A lack of coverage of CBAF medicines in Remume was identified, which may challenge the implementation of PCDT.

护理的完整性是国家药品援助政策(Política Nacional de Assistência Farmacêutica - PNAF)的核心原则之一,也是指导药物使用的两项工具的基础:临床方案和治疗指南(protocolos clínicos e diretrize terapêuticas - PCDT)和基本药物清单。鼓励各城市将这些清单用于医疗保健管理,但城市清单(relações municipais de medicamentos必需品- remme)的制定存在弱点。其目的是从药品援助基本组成部分(Componente Básico da Assistência Farmacêutica - CBAF)无法获得药品的角度描述对PCDT实施的潜在影响。提取到2023年6月前纳入PCDT的CBAF药物。选择了48个城市对感兴趣的药物进行检索和核查。根据最少发现药物的缺失情况对各PCDT进行分析。《目录》平均包含60%(44-75%)所列药物,每种PCDT的平均覆盖率从2%到100%不等。在62个病例中,11个PCDT受到药物可得性低的影响。发现在remme缺乏对CBAF药物的覆盖,这可能对PCDT的实施构成挑战。
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引用次数: 0
Developing epidemiological research in response to an oil spill disaster in Brazil: study design and validation of a questionnaire. 针对巴西漏油事故开展流行病学研究:调查问卷的研究设计和验证。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2024-11-03 DOI: 10.1590/1413-81232026311.06482024
Rita Franco Rêgo, Louise Oliveira Ramos Machado, Francie Sentilles, Luize da Silva Rezende da Mota, Verônica Maria Cadena Lima, Armando Meyer, Amanda Laura Northcross

The oil spill disaster that affected 11 states along the Brazilian coast in 2019/2020 is considered the largest in Brazil's history, with approximately five tons of oil residues collected. Small-scale fishers (SSF) were the group at greatest risk of exposure. This article describes the study design and questionnaire validation of the first epidemiological study in Brazil aimed at investigating the potential health effects of this disaster on SSF. The questionnaire was validated using the Delphi method and consists of 325 questions organized into 13 sections: identification and control, general information, socioeconomic conditions and living situation, work history and organization, fishing activities during the spill, exposure related to spill cleanup, seafood consumption, perceived impacts of the spill, clinical measurements, additional health information, lifestyle, quality of life, and COVID-19. The study design incorporated community engagement approaches. The results will enable the assessment of associations between oil exposure and health outcomes, the monitoring of long-term health effects in this population, and the analysis of the occupational and socioeconomic impacts of the disaster.

2019/2020年影响巴西沿海11个州的石油泄漏灾难被认为是巴西历史上最大的一次,收集了大约5吨的石油残留物。小规模渔民(SSF)是暴露风险最大的群体。本文描述了巴西第一项流行病学研究的研究设计和问卷验证,旨在调查这场灾难对SSF的潜在健康影响。该问卷采用德尔菲法进行验证,由325个问题组成,分为13个部分:识别和控制、一般信息、社会经济条件和生活状况、工作经历和组织、泄漏期间的捕鱼活动、与泄漏清理相关的暴露、海鲜消费、泄漏的感知影响、临床测量、附加健康信息、生活方式、生活质量和COVID-19。研究设计纳入了社区参与方法。这些结果将能够评估接触石油与健康结果之间的关系,监测这一人群的长期健康影响,并分析灾难的职业和社会经济影响。
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引用次数: 0
Pharmaceutical services and the incorporation of psychotropics: therapeutic gaps and opportunities to strengthen SUS. 药物服务和纳入精神药物:加强单一卫生系统的治疗差距和机会。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-30 DOI: 10.1590/1413-81232026311.14222025
Daniela Valdivieso, Luiza Vasconcelos Biglia, Rafael Santos Santana, Samara Jamile Mendes, Patricia Melo Aguiar

This study aimed to analyze the evolution in the incorporation of psychotropics into National List of Essential Medicines (Relação Nacional de Medicamentos Essenciais - RENAME) and whether the current list meets the burden of mental disorders in Brazil. Requests for psychotropics sent to National Commission for the Incorporation of Technologies in the SUS (Comissão Nacional de Incorporação de Tecnologias no SUS - CONITEC) between 2012 and December 2024 were collected and the number of psychotropics for mental disorders in the last eight versions of RENAME was analyzed, as compared to the World Health Organization (WHO) list. Next, the relationship between the number of psychotropics in RENAME 2024 and the burden of disease in Brazil according to the DALY indicator was analyzed. Eleven requests for psychotropics were sent to CONITEC, equivalent to 1.0% of the total, while 90.9% of the demands referred to the incorporation and 9.1% to the expansion of use. Between 2010 and 2014, an increase was observed in the incorporation of psychotropics in RENAME, but the following RENAMEs were not changed. RENAME 2024 includes 18 psychotropics, and 66.7% are funded by the Basic Component. There is a disproportionate relationship between the number of medications for anxiety and depression in RENAME and the high burden of these diseases in Brazil. The findings indicate that the lack of review of RENAME may be impacting the mental health needs of the Brazilian population.

本研究旨在分析精神药物纳入国家基本药物清单(rela o Nacional de Medicamentos Essenciais - RENAME)的演变,以及目前的清单是否满足巴西精神障碍的负担。收集了2012年至2024年12月期间向国家统一目录技术整合委员会(comisso Nacional de Incorporation a o de tecologias no SUS - CONITEC)发送的精神药物请求,并与世界卫生组织(WHO)清单进行比较,分析了RENAME最后八个版本中用于精神障碍的精神药物数量。其次,根据DALY指标分析RENAME 2024中精神药物的数量与巴西疾病负担的关系。精神药物申请11份,占申请总数的1.0%,其中90.9%的申请涉及纳入,9.1%的申请涉及扩大使用。2010年至2014年期间,在RENAME中纳入精神药物的情况有所增加,但以下的RENAME没有改变。RENAME 2024包括18种精神药物,66.7%由基本组成部分资助。在RENAME中,治疗焦虑和抑郁的药物数量与巴西这些疾病的高负担之间存在不成比例的关系。研究结果表明,缺乏对RENAME的审查可能正在影响巴西人口的心理健康需求。
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引用次数: 0
Medicine accessibility in remote areas of the state of Amazonas and the challenges in implementing the PNAF. 亚马逊州偏远地区的药品可及性以及实施PNAF的挑战。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-27 DOI: 10.1590/1413-81232026311.14332025
Genize Kaoany Alves Vasconcelos, Amanda Mamed de Gusmão Lobo, Rana Andressa Castelo Branco Feitosa, Filipe Carvalho Matheus, Luciano Soares, Marina Raijche Mattozo Rover, Norberto Rech, Marcelo Campese, Mareni Rocha Farias

The National Pharmaceutical Policy (Política Nacional de Assistência Farmacêutica - PNAF) takes regional priorities into account. In the Amazon region, social and geographic accessibility indicators are crucial for improving access and ensuring health equity. This study analyzed the organization of pharmaceutical management in 18 municipalities in the countryside of the state of Amazonas. Social, demographic, and structural indicators were described. Medicines accessibility settings (Unidades de Acessibilidade a Medicamentos - UAM), medicine accessibility support settings (Pontos de Apoio à Acessibilidade de Medicamentos - PAAM), and pharmacists were identified. Coverage factors related to Health Centers, territory and population, as well as pharmacists per UAM and per inhabitant, were calculated and suported by selected statements. Access to both the capital city and the most distant village was analyzed. There was at least one UAM in each municipality, and 74% of the establishments stocked medicines. This figure varied between more centralized and decentralized municipalities, with integration with other structures increasing medicine accessibility. The 91 PAAMs serve as a strategy to further increase accessibility, particularly in remote areas with limited infrastructure. The workforce is diversified, with at least one pharmacist in each setting. The synergy between primary health care and pharmaceutical services proved crucial.

国家药品政策(Política Nacional de Assistência Farmacêutica - PNAF)考虑到区域优先事项。在亚马逊地区,社会和地理可及性指标对于改善可及性和确保卫生公平至关重要。本研究分析了亚马逊州农村18个城市的药品管理组织。描述了社会、人口和结构指标。确定了药物可及性设置(Unidades de accessibility bilidade a Medicamentos - UAM)、药物可及性支持设置(Pontos de Apoio Acessibilidade de Medicamentos - PAAM)和药剂师。与保健中心、地区和人口有关的覆盖因素,以及每个UAM和每个居民的药剂师,通过选定的报表进行了计算和支持。分析了通往首都和最偏远村庄的通道。每个市至少有一个联合医院,74%的机构备有药品。这一数字在更集中和分散的城市之间有所不同,与其他结构的整合增加了医疗可及性。91个PAAMs是进一步提高可及性的战略,特别是在基础设施有限的偏远地区。劳动力是多样化的,每个环境中至少有一名药剂师。事实证明,初级保健和药品服务之间的协同作用至关重要。
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引用次数: 0
Regulatory analysis of the integration of oncology pharmaceutical services across the healthcare levels. 跨医疗保健级别整合肿瘤药物服务的监管分析。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-26 DOI: 10.1590/1413-81232026311.14172025
Nathalia de Medeiros Santos Tenório Corrêa, Mario Jorge Sobreira-da-Silva

This study analyzes the regulatory mechanisms governing the integration of pharmaceutical services between high-complexity oncology care and primary health care within the Brazilian Unified Health System. The fragmented care levels undermine treatment continuity, particularly for oncology patients who require ongoing follow-up across both settings. A document analysis of federal regulations in effect from 1990 to 2024 was conducted to identify barriers and facilitators to this integration. The findings indicate that, although normative guidelines are in place, significant challenges persist, including unequal access to expensive medicines, the lack of integrated health information systems, and discontinuous pharmacotherapeutic follow-up. The study advocates for shared care, emphasizing greater collaboration among healthcare teams as a strategy to streamline pharmacotherapy management and ensure care continuity. It concludes that updated regulatory frameworks and coordinated practices are essential to overcoming a fragmented system and ensuring comprehensive and equitable care within the Brazilian Unified Health System.

本研究分析了巴西统一卫生系统内高复杂性肿瘤护理和初级卫生保健之间的药物服务整合的监管机制。分散的护理水平破坏了治疗的连续性,特别是对于需要在两种环境中持续随访的肿瘤患者。对1990年至2024年生效的联邦法规进行了文件分析,以确定这种整合的障碍和促进因素。调查结果表明,尽管有规范性指导方针,但重大挑战仍然存在,包括获得昂贵药物的机会不平等,缺乏综合卫生信息系统,以及不连续的药物治疗随访。该研究提倡共享护理,强调医疗团队之间更大的合作是一种简化药物治疗管理和确保护理连续性的策略。报告的结论是,更新的监管框架和协调的做法对于克服分散的系统和确保巴西统一卫生系统内的全面和公平护理至关重要。
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引用次数: 0
Two decades of the National Pharmaceutical Policy: a commitment to life. 国家药品政策二十年:对生命的承诺。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 DOI: 10.1590/1413-81232026311.13002025
Silvana Nair Leite, Fernanda Manzini, Jorge Carlos Santos da Costa, Jorge Antonio Zapeda Bermudez
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引用次数: 0
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