Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.004
Liang-wen Yan, Li Wei, Li Jia, Wen Li, J. Mu, Shiwei Li
Objective To analyze the alteration of the macula retinal thickness in early stage of type 2 diabetes mellitus and impaired glucose tolerance patients. Methods An observational crosssectional study. After excluding a series of systematic and ocular abnormalities, 62 cases of epidemiology investigative subjects of community residents aged from 45 to 70 were divided into type2 diabetic mellitus (T2DM), impaired glucose tolerance (IGT), and normal control (CTR) group, followed by the WHO DM diagnostic criteria. All the subjects’macula were scanned by spectral-domain ocular coherence tomography (SD-OCT) with the mode of 6mm ETDRS. Data of macular retinal thickness were analyzed using SAS statistic software among the groups. Results With comparison of CTR, macular retinal thickness in T2DM group has the tendency of attenuation; IGT group show thickening. Inner nuclear layer (INL), inner retinal layer (IRL) and outer retinal layer (ORL) inT2DM group were significantly attenuated than those of CTR group. With comparison of T2DM, IGT group has significant thicker in IPL, RPEL, INL and IRL. Conclusions INL might be attenuated and atrophied during early stage of T2DM patients when no diabetic retinopathy occur; IGT might increase the thickness of the inner retina and cause retinal edema. Structural alteration might be occurred during diabetic early stage and IGT, which might differ from and prior to the microangiopathy as well, suggesting that early stage of T2DM and IGT might lead to retinal neurodegeneration. Key words: Diabetic mellitus; Impaired glucose tolerance; Inner retina; Inner plexiform layer; Inner nuclear layer; Neurodegeneration
{"title":"Preliminary analysis of the macular retinal thickness in early stage of type 2 diabetes mellitus and impaired glucose tolerance patients","authors":"Liang-wen Yan, Li Wei, Li Jia, Wen Li, J. Mu, Shiwei Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.004","url":null,"abstract":"Objective \u0000To analyze the alteration of the macula retinal thickness in early stage of type 2 diabetes mellitus and impaired glucose tolerance patients. \u0000 \u0000 \u0000Methods \u0000An observational crosssectional study. After excluding a series of systematic and ocular abnormalities, 62 cases of epidemiology investigative subjects of community residents aged from 45 to 70 were divided into type2 diabetic mellitus (T2DM), impaired glucose tolerance (IGT), and normal control (CTR) group, followed by the WHO DM diagnostic criteria. All the subjects’macula were scanned by spectral-domain ocular coherence tomography (SD-OCT) with the mode of 6mm ETDRS. Data of macular retinal thickness were analyzed using SAS statistic software among the groups. \u0000 \u0000 \u0000Results \u0000With comparison of CTR, macular retinal thickness in T2DM group has the tendency of attenuation; IGT group show thickening. Inner nuclear layer (INL), inner retinal layer (IRL) and outer retinal layer (ORL) inT2DM group were significantly attenuated than those of CTR group. With comparison of T2DM, IGT group has significant thicker in IPL, RPEL, INL and IRL. \u0000 \u0000 \u0000Conclusions \u0000INL might be attenuated and atrophied during early stage of T2DM patients when no diabetic retinopathy occur; IGT might increase the thickness of the inner retina and cause retinal edema. Structural alteration might be occurred during diabetic early stage and IGT, which might differ from and prior to the microangiopathy as well, suggesting that early stage of T2DM and IGT might lead to retinal neurodegeneration. \u0000 \u0000 \u0000Key words: \u0000Diabetic mellitus; Impaired glucose tolerance; Inner retina; Inner plexiform layer; Inner nuclear layer; Neurodegeneration","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"129 1","pages":"672-676"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80346827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.021
Xingxing Chen, Minhong Xiang, Huan-ming Zhou, Wei Zhang, Y. Jia, Qingsong Li, Jing-Yun Gan
Objective To investigate the amount changes and significance of type I and III collagen in the conjunctiva tissue of the patients with conjunctivochalasis. Methods The morphologicalmanifestation of collagen in conjunctival tissues were observed by hematoxylin-eosin staining. The expression of type I and III collagen by immunohistochemical technique in normal human conjunctiva and patients with conjunctivochalasis, combined with the optical density valueof positive stainingresults was measured by Image-Pro-Plus image analysis system, the amount changes of semi quantitative comparison between the two groups of type I and III collagen. Results Theamounts of type I collagen, type III collagen and the type I/III collagen were significantly different in conjunctival tissues of conjunctivochalasis group and the normal group(P 0.05). Conclusions The type I collagenin the conjunctivitis group is lower than in the normal group, while the type III collagen is more than in the normal group, so that the type I/III collagen decrease in the conjunctivochalasis group, which result in the decrease of the mechanical stability of the conjunctival tissue and may be an important reason of conjunctivochalasis. Key words: Conjunctivochalasis; Immunohistochemistry; TypeⅠ collagen; Type Ⅲ collagen
目的探讨结膜松弛症患者结膜组织中ⅰ型和ⅲ型胶原蛋白的含量变化及其意义。方法采用苏木精-伊红染色法观察结膜组织中胶原蛋白的形态表现。采用免疫组化技术检测ⅰ型和ⅲ型胶原蛋白在正常人结膜和结膜松弛症患者中的表达，结合image - pro - plus图像分析系统检测阳性染色结果的光密度值，半定量比较两组ⅰ型和ⅲ型胶原蛋白的量变化。结果结膜松弛组结膜组织中I型胶原、III型胶原及I/III型胶原含量与正常组比较差异有统计学意义(P < 0.05)。结论结膜炎组I型胶原蛋白低于正常组，而III型胶原蛋白高于正常组，使结膜松弛组I/III型胶原蛋白减少，导致结膜组织力学稳定性下降，可能是结膜松弛的重要原因。关键词:结膜松弛;免疫组织化学;Ⅰ型胶原;Ⅲ胶原蛋白
{"title":"Preliminary investigation on collagen inconjunctivochalasis","authors":"Xingxing Chen, Minhong Xiang, Huan-ming Zhou, Wei Zhang, Y. Jia, Qingsong Li, Jing-Yun Gan","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.021","url":null,"abstract":"Objective \u0000To investigate the amount changes and significance of type I and III collagen in the conjunctiva tissue of the patients with conjunctivochalasis. \u0000 \u0000 \u0000Methods \u0000The morphologicalmanifestation of collagen in conjunctival tissues were observed by hematoxylin-eosin staining. The expression of type I and III collagen by immunohistochemical technique in normal human conjunctiva and patients with conjunctivochalasis, combined with the optical density valueof positive stainingresults was measured by Image-Pro-Plus image analysis system, the amount changes of semi quantitative comparison between the two groups of type I and III collagen. \u0000 \u0000 \u0000Results \u0000Theamounts of type I collagen, type III collagen and the type I/III collagen were significantly different in conjunctival tissues of conjunctivochalasis group and the normal group(P 0.05). \u0000 \u0000 \u0000Conclusions \u0000The type I collagenin the conjunctivitis group is lower than in the normal group, while the type III collagen is more than in the normal group, so that the type I/III collagen decrease in the conjunctivochalasis group, which result in the decrease of the mechanical stability of the conjunctival tissue and may be an important reason of conjunctivochalasis. \u0000 \u0000 \u0000Key words: \u0000Conjunctivochalasis; Immunohistochemistry; TypeⅠ collagen; Type Ⅲ collagen","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"28 1","pages":"745-749"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90795094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.019
Chao-wei Tian, Yusheng Wang, D. Hu, G. Dou
Objective To explore the clinical treatment effect of traumatic endophthalmitis. Methods Retrospective cross-sectional study. Clinical records of 44 patients (32 eyes of 32 cases in men and 12 eyes of 12 cases in women) with traumatic endophthalmitis in our hospital were reviewed between January 2010 and January 2016, which included 29 eyes of penetrating injury and 15 eyes of ocular rupture. Preoperative visual acuity was no light perception to 0.8. Thirty-four eyes were treated vitrectomy (12 eyes combined with intraocular foreign body removal). Three eyes were treated vitrectomy after intraocular vitreous cavity injection. Three eyes were treated intraocular vitreous cavity injection. Two eyes were treated only drugs. Two eyes were treated removal of eye contents. In the 34 eyes treated vitrectomy, 36 eyes were injected with silicone oil and 1 eye was injected with C3F8. The patients were followed up for 6 months to 1 year. Results Retina of 32 eyes was reattached and inflammation was controlled in 34 eyes. Eye condition of eleven eyes was stable after removal of silicone oil in 36 eyes. The eye shape was maintained with silicone oil in 25 eyes, of which 10 eyes had poor retinal reattachment. Two eyes were ocular prosthesis. Conclusions Traumatic endophthalmitis is affected by a variety of factors. The prognosis of traumatic endophthalmitis is determined by the nature of the injury, the severity, the treatment measures. The patient can save vision, if early to take active treatment. Key words: Ocular trauma; Endophthalmitis
{"title":"Clinical observation of 44 cases of traumatic endophthalmitis","authors":"Chao-wei Tian, Yusheng Wang, D. Hu, G. Dou","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.019","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.019","url":null,"abstract":"Objective \u0000To explore the clinical treatment effect of traumatic endophthalmitis. \u0000 \u0000 \u0000Methods \u0000Retrospective cross-sectional study. Clinical records of 44 patients (32 eyes of 32 cases in men and 12 eyes of 12 cases in women) with traumatic endophthalmitis in our hospital were reviewed between January 2010 and January 2016, which included 29 eyes of penetrating injury and 15 eyes of ocular rupture. Preoperative visual acuity was no light perception to 0.8. Thirty-four eyes were treated vitrectomy (12 eyes combined with intraocular foreign body removal). Three eyes were treated vitrectomy after intraocular vitreous cavity injection. Three eyes were treated intraocular vitreous cavity injection. Two eyes were treated only drugs. Two eyes were treated removal of eye contents. In the 34 eyes treated vitrectomy, 36 eyes were injected with silicone oil and 1 eye was injected with C3F8. The patients were followed up for 6 months to 1 year. \u0000 \u0000 \u0000Results \u0000Retina of 32 eyes was reattached and inflammation was controlled in 34 eyes. Eye condition of eleven eyes was stable after removal of silicone oil in 36 eyes. The eye shape was maintained with silicone oil in 25 eyes, of which 10 eyes had poor retinal reattachment. Two eyes were ocular prosthesis. \u0000 \u0000 \u0000Conclusions \u0000Traumatic endophthalmitis is affected by a variety of factors. The prognosis of traumatic endophthalmitis is determined by the nature of the injury, the severity, the treatment measures. The patient can save vision, if early to take active treatment. \u0000 \u0000 \u0000Key words: \u0000Ocular trauma; Endophthalmitis","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"1 1","pages":"738-742"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78253411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.008
B. Luo
Objective To explore the repeatability of corneal curvature and astigmatism measurements using Sirius system and the agreement with the TMS-4 conventional topographer in myopia. Methods A prospective control study of 125 patients(125eyes) with myopia before laser vision correction surgery were selected. Measurements of corneal flat keratometry(Kf), steep keratometry(Ks), mean keratometry(Km), corneal astigmatism and axis were taken firstly using Sirius anterior segment analysis system three times to assess the repeatability of the device. The best quality of imagein three acquisitions measured by TMS-4 topographer was chosen for analyzing subsequently. Paired samples t-test and Pearson linear correlation were used for statistical analysis. And a Bland-Altman analysis was used to evaluate the consistency of the two methods of measurement. Results Corneal Kf, Ks, Km, corneal astigmatism and axis measured by Sirius showed high intraobserver repeatability, with all ICC and CoA more than 0.90. Corneal Kf, Km, and astigmatism differences were 0.11±0.14 D, 0.05±0.13 D and-0.12±0.19 D, which were statistically significant, respectively. There were 4.80%,5.60%,5.60%, 5.60% and 5.60% points exceeded 95% LoA of-0.17 to 0.38 D,-0.36 to 0.33 D,-0.20 to0.30 D,-0.50 to 0.26 D and-17.61 to 21.37 degrees for corneal Kf, Ks, Km, astigmatism and axis, respectively. Conclusions Sirius show high repeatability in measurement of corneal curvature and astigmatism, the measurement agreement between Sirius and TMS-4 topographer is not good. Key words: Sirius; TMS-4; Topographer; Keratometry; Astigmatism; Agreement
{"title":"Comparison of corneal curvature and astigmatism measurements in myopia using Sirius Anterior Segment Analysis System and TMS-4 topographer","authors":"B. Luo","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.008","url":null,"abstract":"Objective \u0000To explore the repeatability of corneal curvature and astigmatism measurements using Sirius system and the agreement with the TMS-4 conventional topographer in myopia. \u0000 \u0000 \u0000Methods \u0000A prospective control study of 125 patients(125eyes) with myopia before laser vision correction surgery were selected. Measurements of corneal flat keratometry(Kf), steep keratometry(Ks), mean keratometry(Km), corneal astigmatism and axis were taken firstly using Sirius anterior segment analysis system three times to assess the repeatability of the device. The best quality of imagein three acquisitions measured by TMS-4 topographer was chosen for analyzing subsequently. Paired samples t-test and Pearson linear correlation were used for statistical analysis. And a Bland-Altman analysis was used to evaluate the consistency of the two methods of measurement. \u0000 \u0000 \u0000Results \u0000Corneal Kf, Ks, Km, corneal astigmatism and axis measured by Sirius showed high intraobserver repeatability, with all ICC and CoA more than 0.90. Corneal Kf, Km, and astigmatism differences were 0.11±0.14 D, 0.05±0.13 D and-0.12±0.19 D, which were statistically significant, respectively. There were 4.80%,5.60%,5.60%, 5.60% and 5.60% points exceeded 95% LoA of-0.17 to 0.38 D,-0.36 to 0.33 D,-0.20 to0.30 D,-0.50 to 0.26 D and-17.61 to 21.37 degrees for corneal Kf, Ks, Km, astigmatism and axis, respectively. \u0000 \u0000 \u0000Conclusions \u0000Sirius show high repeatability in measurement of corneal curvature and astigmatism, the measurement agreement between Sirius and TMS-4 topographer is not good. \u0000 \u0000 \u0000Key words: \u0000Sirius; TMS-4; Topographer; Keratometry; Astigmatism; Agreement","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"31 1","pages":"691-694"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78071173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To investigate the clinical manifestation, MRI imaging features and visual function prognosis of sphenoid wing meningioma in the eyes. Methods A retrospective analyzed of 11 patients with sphenoid wing meningioma diagnosed by surgery, the clinical manifestations, the shape and size of lesions in MRI, the relationship with adjacent tissues, as well as postoperative vision, eyeballs and vision recovery. Results Eleven cases of sphenoid wing meningioma patients, the clinical manifestations of ipsilateral visual acuity decreased in 9 cases, 7 cases of eye protrusion, visual field defect in 6 cases. MRI showed 7 cases of orbital cranial tumor, 4 cases of intracranial tumors, the largest diameter of the tumor 2.3cm-8.2cm. T1WI showed moderate and low signal, T2WI showed moderate and high signal, all tumors were evenly enhanced. Tumor and peripheral brain tissue boundary in 9 cases, border blur in 2 cases. Invasion of the optic nerve caused by optic nerve density, location changes in 7 cases. Surgical approach, including the cranial orbital zygomatic approach and pterional approach, as far as possible during the removal of tumor, postoperative follow-up, visual impairment in postoperative visual acuity improved in 2 cases; in the patients with prominent eyes,3 cases returned to normal after operation,and 4 cases had decreased eyes prominence; 3 cases of postoperative vision improved. Conclusions Sphenoid wing meningioma can occur in all age groups, eye symptoms to vision loss, eyeballs, visual field defects, MRI imaging of T1WI mostly moderate and low signal, T2WI is medium and high signal. The tumor density is more consistent. Postoperative visual acuity depends on the preoperative residual vision, the better the prognosis of vision, the better eyeballs and visual field defects, the better prognosis. Key words: Sphenoid ridge meningiomas; MRI; Clinical Features; Visual function prognosis
{"title":"Clinical manifestations and MRI imaging features of sphenoid ridge meningiomas in the eye","authors":"Liyu Zhao, Chao-Hung Wei, Hai-ling Zhao, Xiao-yong Jiang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.018","url":null,"abstract":"Objective \u0000To investigate the clinical manifestation, MRI imaging features and visual function prognosis of sphenoid wing meningioma in the eyes. \u0000 \u0000 \u0000Methods \u0000A retrospective analyzed of 11 patients with sphenoid wing meningioma diagnosed by surgery, the clinical manifestations, the shape and size of lesions in MRI, the relationship with adjacent tissues, as well as postoperative vision, eyeballs and vision recovery. \u0000 \u0000 \u0000Results \u0000Eleven cases of sphenoid wing meningioma patients, the clinical manifestations of ipsilateral visual acuity decreased in 9 cases, 7 cases of eye protrusion, visual field defect in 6 cases. MRI showed 7 cases of orbital cranial tumor, 4 cases of intracranial tumors, the largest diameter of the tumor 2.3cm-8.2cm. T1WI showed moderate and low signal, T2WI showed moderate and high signal, all tumors were evenly enhanced. Tumor and peripheral brain tissue boundary in 9 cases, border blur in 2 cases. Invasion of the optic nerve caused by optic nerve density, location changes in 7 cases. Surgical approach, including the cranial orbital zygomatic approach and pterional approach, as far as possible during the removal of tumor, postoperative follow-up, visual impairment in postoperative visual acuity improved in 2 cases; in the patients with prominent eyes,3 cases returned to normal after operation,and 4 cases had decreased eyes prominence; 3 cases of postoperative vision improved. \u0000 \u0000 \u0000Conclusions \u0000Sphenoid wing meningioma can occur in all age groups, eye symptoms to vision loss, eyeballs, visual field defects, MRI imaging of T1WI mostly moderate and low signal, T2WI is medium and high signal. The tumor density is more consistent. Postoperative visual acuity depends on the preoperative residual vision, the better the prognosis of vision, the better eyeballs and visual field defects, the better prognosis. \u0000 \u0000 \u0000Key words: \u0000Sphenoid ridge meningiomas; MRI; Clinical Features; Visual function prognosis","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"28 24","pages":"734-737"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72496209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.005
Zhenli Lin, Xiaoyan Dou, Jiang Guo, Jiali Chen, Zhenzhou Li
Objective To explore the relationship between retinal vein occlusion (RVO) and carotid artery lesion and the hemodynamic changes of ocular and carotid arteries using Colour Doppler Flow Imaging (CDFI). Methods Twenty-two patients (22 eyes) were enrolled with RVO diagnosed by fundus fluoresecine angiography (FFA) who presented to Shenzhen Second People’s Hospital,from October 2015 to December 2016. Age of patients ranged from 25 years to 85 years (56.8±15.4years); 26 patients (26 eyes) were enrolled as controlled group with the age ranged from 30 years to 81 years (56.4±13.1years). CDFI was performed to detect the quantity and appearance of carotid artery plagues, the degree of stenosis and the parameters of internal carotid artery (ICA), ophthalmic artery (OA), central retinal artery (CRA) and central retinal vein (CRV) hemodynamic. Results In all 22 cases diagnosed by FFA, carotid artery lesions were detected in 15 (68.2%, 15/22) patients. Compared with the controlled group, the peak systolic velocity (PSV), end diastolic velocity (EDV), resistance index (RI) of ICA, OA, CRA, CRV were not statistically significant (P >0.05). Compared with the healthy side, the RI of ICA and EDV of CRA were statistically different (P 0.05) while there were no differences in coronary heartdisease, stroke, smoking, age and gender between RVO group and controlled group (P <0.05). Conclusions There is a relationship between RVO and carotid artery lesions. CDFI could indirectly measure the carotid artery lesions and hemodynamic parameters of the ocular and carotid arteries. However, whether CDFI could be used to investigate the condition and the progress of RVO should be further explored. Key words: Retinal vein occlusion; CDFI; Hemodynamics; Carotid artery; Ocular artery
{"title":"Relationship between retinal vein occlusion with carotid artery lesions and hemodynamic changes","authors":"Zhenli Lin, Xiaoyan Dou, Jiang Guo, Jiali Chen, Zhenzhou Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.005","url":null,"abstract":"Objective \u0000To explore the relationship between retinal vein occlusion (RVO) and carotid artery lesion and the hemodynamic changes of ocular and carotid arteries using Colour Doppler Flow Imaging (CDFI). \u0000 \u0000 \u0000Methods \u0000Twenty-two patients (22 eyes) were enrolled with RVO diagnosed by fundus fluoresecine angiography (FFA) who presented to Shenzhen Second People’s Hospital,from October 2015 to December 2016. Age of patients ranged from 25 years to 85 years (56.8±15.4years); 26 patients (26 eyes) were enrolled as controlled group with the age ranged from 30 years to 81 years (56.4±13.1years). CDFI was performed to detect the quantity and appearance of carotid artery plagues, the degree of stenosis and the parameters of internal carotid artery (ICA), ophthalmic artery (OA), central retinal artery (CRA) and central retinal vein (CRV) hemodynamic. \u0000 \u0000 \u0000Results \u0000In all 22 cases diagnosed by FFA, carotid artery lesions were detected in 15 (68.2%, 15/22) patients. Compared with the controlled group, the peak systolic velocity (PSV), end diastolic velocity (EDV), resistance index (RI) of ICA, OA, CRA, CRV were not statistically significant (P >0.05). Compared with the healthy side, the RI of ICA and EDV of CRA were statistically different (P 0.05) while there were no differences in coronary heartdisease, stroke, smoking, age and gender between RVO group and controlled group (P <0.05). \u0000 \u0000 \u0000Conclusions \u0000There is a relationship between RVO and carotid artery lesions. CDFI could indirectly measure the carotid artery lesions and hemodynamic parameters of the ocular and carotid arteries. However, whether CDFI could be used to investigate the condition and the progress of RVO should be further explored. \u0000 \u0000 \u0000Key words: \u0000Retinal vein occlusion; CDFI; Hemodynamics; Carotid artery; Ocular artery","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"163 2 1","pages":"677-681"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83296404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.013
Daowei Qian, Hongyang Zhang, Y. Niu, Yanqiu Liao
Objective To compare vision-related quality of life (QOL) in implantable Collamer lens (ICL) recipients and Artisan iris-fixed Phakic intraocular lens (Artisan PIOL) recipients in high myopia. Methods Retrospective study. There were ICL patients 17 cases (34 eyes), and Artisan PIOL patients 15 cases (30 eyes).in Department of Ophthalmology, Guangdong General Hospital. QOL was measured with quality of life impact of refractive correction (QIRC) in consecutive patients at 3 months after ICL or Artisan PIOL implantation in high myopia. Independent-sample t tests (version 13.00, SPSS, Inc.) were used for statistical comparison of overall QIRC scores and in an exploratoryanalysis of scores for individual questionnaire items between ICL group and Artisan PIOL group. Results Before surgery, the average age (27.59±6.07 vs 26.87±4.84), spherical equivalent (-11.07±1.91D vs-11.51±2.11D) were similar in ICL recipients and Artisan PIOL respectively (P=0.715, 0.383). QIRC scores were significantly higher (P=0.001) in ICL recipients (47.98±3.60) than in Artisan PIOL (43.54±2.87). The score of item 2, 12, 20 in ICL recipients were significant difference than in Artisan PIOL (P=0.010, 0.043, 0.002). Conclusions ICL implantation may offer significant QOL advantages over Artisan PIOL in patients with high myopia. Key words: Implantable collamer lens; Phakic; Quality of life; High myopia
{"title":"A survey of the quality of life in high myopia in implantable Collamer lens and Artisan PIOL recipients","authors":"Daowei Qian, Hongyang Zhang, Y. Niu, Yanqiu Liao","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.013","url":null,"abstract":"Objective \u0000To compare vision-related quality of life (QOL) in implantable Collamer lens (ICL) recipients and Artisan iris-fixed Phakic intraocular lens (Artisan PIOL) recipients in high myopia. \u0000 \u0000 \u0000Methods \u0000Retrospective study. There were ICL patients 17 cases (34 eyes), and Artisan PIOL patients 15 cases (30 eyes).in Department of Ophthalmology, Guangdong General Hospital. QOL was measured with quality of life impact of refractive correction (QIRC) in consecutive patients at 3 months after ICL or Artisan PIOL implantation in high myopia. Independent-sample t tests (version 13.00, SPSS, Inc.) were used for statistical comparison of overall QIRC scores and in an exploratoryanalysis of scores for individual questionnaire items between ICL group and Artisan PIOL group. \u0000 \u0000 \u0000Results \u0000Before surgery, the average age (27.59±6.07 vs 26.87±4.84), spherical equivalent (-11.07±1.91D vs-11.51±2.11D) were similar in ICL recipients and Artisan PIOL respectively (P=0.715, 0.383). QIRC scores were significantly higher (P=0.001) in ICL recipients (47.98±3.60) than in Artisan PIOL (43.54±2.87). The score of item 2, 12, 20 in ICL recipients were significant difference than in Artisan PIOL (P=0.010, 0.043, 0.002). \u0000 \u0000 \u0000Conclusions \u0000ICL implantation may offer significant QOL advantages over Artisan PIOL in patients with high myopia. \u0000 \u0000 \u0000Key words: \u0000Implantable collamer lens; Phakic; Quality of life; High myopia","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"43 1","pages":"713-717"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88435267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.006
X. Ding, Yuxi Zheng, P. Chang
Objective To describe the early experience with the femtosecond Laser-assisted cataract surgery. Methods This study involved 85 continuous patients (114 eyes) who planned to have femtosecond laser-assisted cataract surgeries. All eyes were divided into 2 groups: Group 1 (first 50 eyes) and Group 2 (eyes 51 through 114). All femtosecond laser-assisted (LenSx, Alcon, Fort Worth, TX) cataract surgeries were performed by the same experienced cataract surgeon (also experienced with corneal refractive surgeries). Femtosecond laser procedures included anterior capsulotomy, lens segmentation, and clear corneal incision creation. All abnormalities and complications during the surgeries were recorded. Results The mean age of patients in 2 groups was 60.4±14.9 years and 60.9±16.2 years, respectively. There was no significant difference was found between the 2 groups. The numbers of docking attempts and occurrence rates of subconjunctival hemorrhage of 2 groups were 1.14±0.50 and 1.19±0.53, 22.0% (11 eyes) and 34.4% (22 eyes), respectively. However, both of them showed no significant differences between the 2 groups. The occurrence rates of corneal incision creation assisted with keratome in 2 groups were 26% (13 eyes) and 17.2% (11 eyes), miosis after the laser procedure were 2% (1 eye) and 1.6% (1 eye), anterior capsular tags were 4% (2 eyes) and 3.1% (2 eye), anterior capsular tear were 4% (2 eyes) and 3.1% (2 eyes), posterior capsular tearwere 2% (1 eye) and 0; No significant differences were found in those complication occurrence rates between the 2 groups (P ranged from 0.252 to 0.801). Conclusions FLACS is proved to be very safe for the experienced cataract surgeon, especially for those who also possess rich experiences in corneal refractive surgeries. The learning curve has no significant effect on the abnormalities and complications occurrence during the surgery. Key words: Femtasecond; Cataract; Learning curve; Complication
目的探讨飞秒激光辅助白内障手术的早期经验。方法对85例(114眼)计划行飞秒激光辅助白内障手术的患者进行研究。所有眼睛分为2组:1组(前50只眼睛)和2组(51 ~ 114只眼睛)。所有飞秒激光辅助白内障手术(LenSx, Alcon, Fort Worth, TX)均由同一名经验丰富的白内障外科医生(也有角膜屈光手术经验)进行。飞秒激光手术包括前囊切开术、晶状体分割术和透明角膜切口术。记录手术过程中所有异常及并发症。结果两组患者平均年龄分别为60.4±14.9岁和60.9±16.2岁。两组间差异无统计学意义。两组结膜下出血发生率分别为1.14±0.50、1.19±0.53、22.0%(11眼)、34.4%(22眼)。但两组间均无显著差异。两组角膜切口辅助角膜切割的发生率分别为26%(13眼)和17.2%(11眼)，激光手术后角膜缩小的发生率分别为2%(1眼)和1.6%(1眼)，前囊脱落的发生率分别为4%(2眼)和3.1%(2眼)，前囊撕裂的发生率分别为4%(2眼)和3.1%(2眼)，后囊膜撕裂的发生率分别为2%(1眼)和0;两组患者并发症发生率比较差异无统计学意义(P值为0.252 ~ 0.801)。结论FLACS对于经验丰富的白内障外科医生，特别是具有丰富角膜屈光手术经验的外科医生是非常安全的。学习曲线对手术异常及并发症的发生无显著影响。关键词:飞秒;白内障;学习曲线;并发症
{"title":"Early experience with the femtosecond laser-assisted cataract surgery","authors":"X. Ding, Yuxi Zheng, P. Chang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.006","url":null,"abstract":"Objective \u0000To describe the early experience with the femtosecond Laser-assisted cataract surgery. \u0000 \u0000 \u0000Methods \u0000This study involved 85 continuous patients (114 eyes) who planned to have femtosecond laser-assisted cataract surgeries. All eyes were divided into 2 groups: Group 1 (first 50 eyes) and Group 2 (eyes 51 through 114). All femtosecond laser-assisted (LenSx, Alcon, Fort Worth, TX) cataract surgeries were performed by the same experienced cataract surgeon (also experienced with corneal refractive surgeries). Femtosecond laser procedures included anterior capsulotomy, lens segmentation, and clear corneal incision creation. All abnormalities and complications during the surgeries were recorded. \u0000 \u0000 \u0000Results \u0000The mean age of patients in 2 groups was 60.4±14.9 years and 60.9±16.2 years, respectively. There was no significant difference was found between the 2 groups. The numbers of docking attempts and occurrence rates of subconjunctival hemorrhage of 2 groups were 1.14±0.50 and 1.19±0.53, 22.0% (11 eyes) and 34.4% (22 eyes), respectively. However, both of them showed no significant differences between the 2 groups. The occurrence rates of corneal incision creation assisted with keratome in 2 groups were 26% (13 eyes) and 17.2% (11 eyes), miosis after the laser procedure were 2% (1 eye) and 1.6% (1 eye), anterior capsular tags were 4% (2 eyes) and 3.1% (2 eye), anterior capsular tear were 4% (2 eyes) and 3.1% (2 eyes), posterior capsular tearwere 2% (1 eye) and 0; No significant differences were found in those complication occurrence rates between the 2 groups (P ranged from 0.252 to 0.801). \u0000 \u0000 \u0000Conclusions \u0000FLACS is proved to be very safe for the experienced cataract surgeon, especially for those who also possess rich experiences in corneal refractive surgeries. The learning curve has no significant effect on the abnormalities and complications occurrence during the surgery. \u0000 \u0000 \u0000Key words: \u0000Femtasecond; Cataract; Learning curve; Complication","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"309 1","pages":"682-686"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78255789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.014
Mei Liu
Objective To evaluate the efficacy of intravitreal ranibizumab (IVR) for the treatment of threshold retinopathy of prematurity (ROP). Methods A total of 98 premature infants (190 eyes) with diagnosis of threshold ROP were reviewed and analyzed in this study. All the infants received IVR (10 mg/ml, 0.025ml) as the initial treatment within 24 hours after diagnosis. Anterior segment examinations were performed after injection in first 3 days, and fundus examination were performed after treatment in third day, first week third week and eighth week, and determined the follow-up examinations time according to condition and correct gestational age. Follow-up ranged from 8 to 48 weeks, and the average follow-up time was (32.1±10.5) weeks. If the infants didn’t respond positively to the treatment, IVR or laser photocoagulation treatment was performed once more. Results After receiving IVR injections, 128 eyes (67.37%) exhibited ROP regression. Among the eyes, the development of peripheral retinal vessels could be observed in 105 eyes (55.26%) which received a single injection; clinical improvement in 23 eye (12.11%) which received repeat injection; stable disease in 56 eyes (29.47%) which received laser therapy; needing-advance treatment disease in 6 eyes (3.16%). Conclusions IVR is safe and effective for most threshold ROP infants. In cases of recurrence or no response, conventional laser treatment or an additional IVR injection were needed for the others. Key words: Retinopathy; Threshold retinopathy of prematurity; Treatment; Intravitreal ranibizumab
{"title":"Curative effect analysis of intravitreal Ranibizumab for the treatment of retinopathy of prematurity","authors":"Mei Liu","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.014","url":null,"abstract":"Objective \u0000To evaluate the efficacy of intravitreal ranibizumab (IVR) for the treatment of threshold retinopathy of prematurity (ROP). \u0000 \u0000 \u0000Methods \u0000A total of 98 premature infants (190 eyes) with diagnosis of threshold ROP were reviewed and analyzed in this study. All the infants received IVR (10 mg/ml, 0.025ml) as the initial treatment within 24 hours after diagnosis. Anterior segment examinations were performed after injection in first 3 days, and fundus examination were performed after treatment in third day, first week third week and eighth week, and determined the follow-up examinations time according to condition and correct gestational age. Follow-up ranged from 8 to 48 weeks, and the average follow-up time was (32.1±10.5) weeks. If the infants didn’t respond positively to the treatment, IVR or laser photocoagulation treatment was performed once more. \u0000 \u0000 \u0000Results \u0000After receiving IVR injections, 128 eyes (67.37%) exhibited ROP regression. Among the eyes, the development of peripheral retinal vessels could be observed in 105 eyes (55.26%) which received a single injection; clinical improvement in 23 eye (12.11%) which received repeat injection; stable disease in 56 eyes (29.47%) which received laser therapy; needing-advance treatment disease in 6 eyes (3.16%). \u0000 \u0000 \u0000Conclusions \u0000IVR is safe and effective for most threshold ROP infants. In cases of recurrence or no response, conventional laser treatment or an additional IVR injection were needed for the others. \u0000 \u0000 \u0000Key words: \u0000Retinopathy; Threshold retinopathy of prematurity; Treatment; Intravitreal ranibizumab","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"29 1","pages":"718-721"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73709245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.007
Bing-zhen Li, K. Feng
Objective To evaluate the application of coreoplasty in severe eye injuries. Investigate the role of coreoplasty in silicone oil eyes with iris defects in preventing the prolapse of silicon oil into the anterior chamber. Methods In this case-series study, severe eye injury cases with iris defects were selected from Eye Injury Vitrectomy Study (EIVS) database. The proportion of coreoplasty surgery was analyzed and the differences between the non-coreoplasty group and coreoplasty group in the incidence of silicon oil efflux into the anterior chamber were compared. Data were analyzed using χ2 test. Results Information of 1377 eyes in the EIVS database was explored, 245 cases (17.8%) showed traumatic iris defects and overall 76 eyes (31.0%) were undergone coreoplasty. In 128 silicon oil tamponated eyes with iris defects, the analysis revealed silicon oil efflux into the anterior chamber to be significantly more frequent in non-coreoplasty group (χ2=5.269, P=0.021). Conclusions In severe eye injuries with iris defects, the coreoplasty surgery should be more widely performed. In silicon oil eyes with iris defects, coreoplasty surgery could be advantage to minimize the risk of silicon oil efflux into the anterior chamber. Key words: Eye injury; Coreoplasty; Silicone oil eye; Complication
{"title":"A case-series study on coreoplasty in severe eye injuries","authors":"Bing-zhen Li, K. Feng","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.007","url":null,"abstract":"Objective \u0000To evaluate the application of coreoplasty in severe eye injuries. Investigate the role of coreoplasty in silicone oil eyes with iris defects in preventing the prolapse of silicon oil into the anterior chamber. \u0000 \u0000 \u0000Methods \u0000In this case-series study, severe eye injury cases with iris defects were selected from Eye Injury Vitrectomy Study (EIVS) database. The proportion of coreoplasty surgery was analyzed and the differences between the non-coreoplasty group and coreoplasty group in the incidence of silicon oil efflux into the anterior chamber were compared. Data were analyzed using χ2 test. \u0000 \u0000 \u0000Results \u0000Information of 1377 eyes in the EIVS database was explored, 245 cases (17.8%) showed traumatic iris defects and overall 76 eyes (31.0%) were undergone coreoplasty. In 128 silicon oil tamponated eyes with iris defects, the analysis revealed silicon oil efflux into the anterior chamber to be significantly more frequent in non-coreoplasty group (χ2=5.269, P=0.021). \u0000 \u0000 \u0000Conclusions \u0000In severe eye injuries with iris defects, the coreoplasty surgery should be more widely performed. In silicon oil eyes with iris defects, coreoplasty surgery could be advantage to minimize the risk of silicon oil efflux into the anterior chamber. \u0000 \u0000 \u0000Key words: \u0000Eye injury; Coreoplasty; Silicone oil eye; Complication","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":"14 1","pages":"687-690"},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73499758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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