Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.022
Hai-yan Sun, Wenting Sun, G. An
Objective To observe protective effect of progesterone on rat Optic Nerve after optic nerve crush. Methods Fifty female SD rats were randomly divided into three groups, normal group with 10 rats (20 eyes, the normal group had no treatment), control group with 20 rats and treatment group with 20 rats. Mis-classification damage analogues were made on control group and treated group. For the treatment group, progesterone was injected to the rats’ abdominal cavity (10mg/kg) after one hour of injury, for once a day and until the end of experiment. For the control group, distilled water was injected to the rats’ abdominal cavity (10mg/kg) after one hour of injury, for once a day and until the end of experiment. Four optic retinas of every group were taken. Fixed, embedded, sliced for HE staining to observe the morphological changes of the retina and detect the mean OD value of IGF-1 and AQP-4. Results The expression of IGF-1 in control group enhanced significantly after 1 day, 3 days and 7days of injury (P <0.05) and began to decrease at the 14th day.The expressions of IGF-1 in treatment group were significantly obvious than that of control group at every time point after injury and there was significant difference between the two group (P <0.05). The expression of AQP-4 in control group began to increase after one day of injury, reached the highest level at the third day, began to decrease at the 7th day and closed to normal level at the 28th day. Except for the 28th day the positive expressions of AQP-4 in treatment group at the first day, 3rd day, 7th day and 14th day were significantly lower than that of control. Conclusions The expression of IGF-1 and AQP-4 in normal retinal tissue is positive and it increases after incomplete injury of the optic nerve. IGF-1 and AQP-4 participate the process of incomplete injury of rats’ optic nerve. Progesterone can decrease the expression of AQP-4 and increase the expression of IGF-1 in the rat retinal tissue after the incomplete injury of optic nerve. Progesterone can promote the regeneration and repair of retina cell. Key words: Optic nerve; Progesterone; Retina ganglion cell; Insulin-like growth factor-1; Aquaporin-4
{"title":"Protective effect of progesterone on rat optic nerve after optic nerve crush","authors":"Hai-yan Sun, Wenting Sun, G. An","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.022","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.022","url":null,"abstract":"Objective \u0000To observe protective effect of progesterone on rat Optic Nerve after optic nerve crush. \u0000 \u0000 \u0000Methods \u0000Fifty female SD rats were randomly divided into three groups, normal group with 10 rats (20 eyes, the normal group had no treatment), control group with 20 rats and treatment group with 20 rats. Mis-classification damage analogues were made on control group and treated group. For the treatment group, progesterone was injected to the rats’ abdominal cavity (10mg/kg) after one hour of injury, for once a day and until the end of experiment. For the control group, distilled water was injected to the rats’ abdominal cavity (10mg/kg) after one hour of injury, for once a day and until the end of experiment. Four optic retinas of every group were taken. Fixed, embedded, sliced for HE staining to observe the morphological changes of the retina and detect the mean OD value of IGF-1 and AQP-4. \u0000 \u0000 \u0000Results \u0000The expression of IGF-1 in control group enhanced significantly after 1 day, 3 days and 7days of injury (P <0.05) and began to decrease at the 14th day.The expressions of IGF-1 in treatment group were significantly obvious than that of control group at every time point after injury and there was significant difference between the two group (P <0.05). The expression of AQP-4 in control group began to increase after one day of injury, reached the highest level at the third day, began to decrease at the 7th day and closed to normal level at the 28th day. Except for the 28th day the positive expressions of AQP-4 in treatment group at the first day, 3rd day, 7th day and 14th day were significantly lower than that of control. \u0000 \u0000 \u0000Conclusions \u0000The expression of IGF-1 and AQP-4 in normal retinal tissue is positive and it increases after incomplete injury of the optic nerve. IGF-1 and AQP-4 participate the process of incomplete injury of rats’ optic nerve. Progesterone can decrease the expression of AQP-4 and increase the expression of IGF-1 in the rat retinal tissue after the incomplete injury of optic nerve. Progesterone can promote the regeneration and repair of retina cell. \u0000 \u0000 \u0000Key words: \u0000Optic nerve; Progesterone; Retina ganglion cell; Insulin-like growth factor-1; Aquaporin-4","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73503499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.006
Pingli Zhu, Zhuoshi Wang, Liang-bao An, Ling-Xian Xu
Objective To assess the effects of intravitreal conbercept in treating delayed post-vitrectomy (4 weeks after surgery) diabetic vitreous hemorrhage (PVDVH). Methods Of 36 consecu-tive patients (36 eyes) with delayed PVDVH were assigned to tow groups, the study group (17 eyes) and the control group (19 eyes). The study group was treated with intravitreal conbercept, and repeated injection was given after 4 weeks in cases with no obvious blood absorption, until the blood was absorbed completely. The control group was given Chinese traditional medicine and iodized lecithin. The average follow-up duration was 8.5±2.5 months (ranged, 5~13 months). Results VCT of the study group was 2-8 weeks, mean 5.3±2.3 weeks, with average injection 2.2±0.8 times. Four eyes had developed recurrent vitreous hemorrhage (VH), but all of the eyes had a clear vitreous at the end of study period, and no vitrectomy surgery was needed. In the control group, eight eyes had spontaneous reabsorption in 3-9 weeks, mean 6.7±2.5 weeks, 11 eyes developed recurrent VH, the blood of one eye finally had been absorbed, 10 eyes had persistent VH, 4 eyes of them had iris neouvasculrization, and 4 eyes of them had retinal detachment, and finally these 10 eyes underwent revitrectomy surgeries. The vision of the study group was better than that in the control group. Conclusions Intravitreal conbercept treatment can accelerate the clear-up of the VH, reduce the complication and the need of revitrectomy for PVDVH. Key words: Conbercept; Diabetic retinopathy; Recurrent vitreous haemorrhage
{"title":"Intravitreal conbercept injection for recurrent vitreous haemorrhage after diabetic vitrectomy","authors":"Pingli Zhu, Zhuoshi Wang, Liang-bao An, Ling-Xian Xu","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.006","url":null,"abstract":"Objective \u0000To assess the effects of intravitreal conbercept in treating delayed post-vitrectomy (4 weeks after surgery) diabetic vitreous hemorrhage (PVDVH). \u0000 \u0000 \u0000Methods \u0000Of 36 consecu-tive patients (36 eyes) with delayed PVDVH were assigned to tow groups, the study group (17 eyes) and the control group (19 eyes). The study group was treated with intravitreal conbercept, and repeated injection was given after 4 weeks in cases with no obvious blood absorption, until the blood was absorbed completely. The control group was given Chinese traditional medicine and iodized lecithin. The average follow-up duration was 8.5±2.5 months (ranged, 5~13 months). \u0000 \u0000 \u0000Results \u0000VCT of the study group was 2-8 weeks, mean 5.3±2.3 weeks, with average injection 2.2±0.8 times. Four eyes had developed recurrent vitreous hemorrhage (VH), but all of the eyes had a clear vitreous at the end of study period, and no vitrectomy surgery was needed. In the control group, eight eyes had spontaneous reabsorption in 3-9 weeks, mean 6.7±2.5 weeks, 11 eyes developed recurrent VH, the blood of one eye finally had been absorbed, 10 eyes had persistent VH, 4 eyes of them had iris neouvasculrization, and 4 eyes of them had retinal detachment, and finally these 10 eyes underwent revitrectomy surgeries. The vision of the study group was better than that in the control group. \u0000 \u0000 \u0000Conclusions \u0000Intravitreal conbercept treatment can accelerate the clear-up of the VH, reduce the complication and the need of revitrectomy for PVDVH. \u0000 \u0000 \u0000Key words: \u0000Conbercept; Diabetic retinopathy; Recurrent vitreous haemorrhage","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72830397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.014
Q. Lin, Xuexi Li
Objective To compare the clinical curative effect of iris localization and Kappa Angle correction on femtosecond LASIK surgery. Methods Prospective randomized controlled study. Matching t test was used on two groups of postoperative 1 month visual acuity, contrast sensitivity respectively and preoperative best corrected visual acuity, best corrected vision wear glasses measuring contrast sensitivity. Two independent sample t test and nonparametric test were used on between the two groups of postoperative 1 month visual acuity, contrast sensitivity compared with preoperative best corrected visual acuity, best corrected vision wear glasses contrast sensitivity increased value and Pentacam measurement of cutting off center value pairs. Two groups of postoperative 1 month visual acuity, contrast sensitivity increased value with Pentacam measurement of cutting off center value, postoperative residual spherical mirror, l enticular mirror and cylindrical mirror axis for correlation analysis. Results Two groups of postoperative 1 month visual acuity, contrast sensitivity and preoperative best corrected visual acuity, best corrected vision wear glasses measuring contrast sensitivity difference was statistically significant. Between the two groups of postoperative 1 month visual acuity, contrast sensitivity and Pentacam measurement of cutting off center value differences had no statistical significance. Conclusions The two kinds of operation method can effectively avoid cutting off center of LASIK, get better than that of preoperative vision and contrast sensitivity. Two kinds of operation method postoperative visual acuity, contrast sensitivity increase value and cutting off center has no difference. Key words: Femtosecond laser; The iris localization; Kappa Angle correction
{"title":"Clinical curative effect comparison of the iris localization and Kappa angle correction femtosecond LASIK","authors":"Q. Lin, Xuexi Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.014","url":null,"abstract":"Objective \u0000To compare the clinical curative effect of iris localization and Kappa Angle correction on femtosecond LASIK surgery. \u0000 \u0000 \u0000Methods \u0000Prospective randomized controlled study. Matching t test was used on two groups of postoperative 1 month visual acuity, contrast sensitivity respectively and preoperative best corrected visual acuity, best corrected vision wear glasses measuring contrast sensitivity. Two independent sample t test and nonparametric test were used on between the two groups of postoperative 1 month visual acuity, contrast sensitivity compared with preoperative best corrected visual acuity, best corrected vision wear glasses contrast sensitivity increased value and Pentacam measurement of cutting off center value pairs. Two groups of postoperative 1 month visual acuity, contrast sensitivity increased value with Pentacam measurement of cutting off center value, postoperative residual spherical mirror, l enticular mirror and cylindrical mirror axis for correlation analysis. \u0000 \u0000 \u0000Results \u0000Two groups of postoperative 1 month visual acuity, contrast sensitivity and preoperative best corrected visual acuity, best corrected vision wear glasses measuring contrast sensitivity difference was statistically significant. Between the two groups of postoperative 1 month visual acuity, contrast sensitivity and Pentacam measurement of cutting off center value differences had no statistical significance. \u0000 \u0000 \u0000Conclusions \u0000The two kinds of operation method can effectively avoid cutting off center of LASIK, get better than that of preoperative vision and contrast sensitivity. Two kinds of operation method postoperative visual acuity, contrast sensitivity increase value and cutting off center has no difference. \u0000 \u0000 \u0000Key words: \u0000Femtosecond laser; The iris localization; Kappa Angle correction","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76965121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.021
Huade Wang, Qingsheng Zhang, Lan Shen, Erying Han, Lin Wei
Objective To investigate the therapeutic effect of visual training on low vision of no amblyopia. Methods A prospective study. A total of 56 children with low vision of no amblyopia were selected which came to Puyang Eye Hospital during a period from February 2015 to May 2016 to accept an visual training lasted for 4 weeks. All of the children met the following criteria: the degree of refractive power was-1.00 D~+3.00 D, without anisometropia, the discrepancy of corrected visual acuity of two eyes was less than two rows on standard visual acuity chart, the corrected visual acuity was below normal children, aged from 5 to 12 years old. The monocular corrected visual acuity, uncorrected visual acuity, monocular Flipper cycle and amplitude of monocular accommodation before and after the visual training were measured. Results The average binocular uncorrected visual acuity of the 56 children was 0.53±0.13 before training and was 0.91±0.14 after training, with statistical difference (t=3.2657, P <0.05). The average binocular corrected visual acuity was 0.59±0.12 before training and was 0.98±0.05 after training, with statistical difference (t=3.3724, P <0.05). The Flipper cycle of right eye before and after training respectively was 5.8±2.6 and 18.2±1.7, with statistical difference (t=13.6285, P <0.05). The Flipper cycle of left eye before and after training respectively was 6.3±1.9 and 18.5±1.3, with statistical difference (t=12.8354, P <0.05). The amplitude of accommodation of right eye was 8.9±2.5 D before training and was 15.1±1.2 D after training, with statistical difference (t=20.1624, P <0.05). The amplitude of accommodation of left eye was 8.6±2.2 D before training and was 15.3±1.1 D after training, with statistical difference (t=21.6218, P <0.05). Conclusions Visual training can effectively improve the adjust sensitivity and the amplitude of accommodation, uncorrected visual acuity and corrected visual acuity of low vision of no amblyopia. This suggests that the low vision of these patients is caused by dysfunction of accommodation. Key words: Visual training; Low vision; Amplitude of accommodation; Adjust sensitivity
目的探讨视力训练对无弱视低视力的治疗效果。方法前瞻性研究。选取2015年2月至2016年5月来濮阳眼科医院接受为期4周的视力训练的无弱视低视力儿童56例。所有患儿均符合以下标准:屈光度为-1.00 D~+3.00 D，无屈光参差，两眼矫正视力差小于标准视力表两列，矫正视力低于正常儿童，年龄5 ~ 12岁。测量视觉训练前后的单眼矫正视力、未矫正视力、单眼鳍波周期和单眼调节幅度。结果56例患儿训练前平均双眼未矫正视力为0.53±0.13，训练后平均双眼未矫正视力为0.91±0.14，差异有统计学意义(t=3.2657, P <0.05)。训练前双眼平均矫正视力为0.59±0.12，训练后平均矫正视力为0.98±0.05，差异有统计学意义(t=3.3724, P <0.05)。训练前后右眼翻转周期分别为5.8±2.6和18.2±1.7，差异有统计学意义(t=13.6285, P <0.05)。训练前后左眼鳍转周期分别为6.3±1.9和18.5±1.3，差异有统计学意义(t=12.8354, P <0.05)。训练前右眼调节幅度为8.9±2.5 D，训练后为15.1±1.2 D，差异有统计学意义(t=20.1624, P <0.05)。训练前左眼调节振幅为8.6±2.2 D，训练后为15.3±1.1 D，差异有统计学意义(t=21.6218, P <0.05)。结论视力训练可有效提高无弱视低视力患者的调节灵敏度和调节幅度、未矫正视力和矫正视力。这表明这些患者的低视力是由调节功能障碍引起的。关键词:视觉训练;低视力;调节幅度;调整灵敏度
{"title":"Therapeutic effect of visual training on low vision of no amblyopia","authors":"Huade Wang, Qingsheng Zhang, Lan Shen, Erying Han, Lin Wei","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.021","url":null,"abstract":"Objective \u0000To investigate the therapeutic effect of visual training on low vision of no amblyopia. \u0000 \u0000 \u0000Methods \u0000A prospective study. A total of 56 children with low vision of no amblyopia were selected which came to Puyang Eye Hospital during a period from February 2015 to May 2016 to accept an visual training lasted for 4 weeks. All of the children met the following criteria: the degree of refractive power was-1.00 D~+3.00 D, without anisometropia, the discrepancy of corrected visual acuity of two eyes was less than two rows on standard visual acuity chart, the corrected visual acuity was below normal children, aged from 5 to 12 years old. The monocular corrected visual acuity, uncorrected visual acuity, monocular Flipper cycle and amplitude of monocular accommodation before and after the visual training were measured. \u0000 \u0000 \u0000Results \u0000The average binocular uncorrected visual acuity of the 56 children was 0.53±0.13 before training and was 0.91±0.14 after training, with statistical difference (t=3.2657, P <0.05). The average binocular corrected visual acuity was 0.59±0.12 before training and was 0.98±0.05 after training, with statistical difference (t=3.3724, P <0.05). The Flipper cycle of right eye before and after training respectively was 5.8±2.6 and 18.2±1.7, with statistical difference (t=13.6285, P <0.05). The Flipper cycle of left eye before and after training respectively was 6.3±1.9 and 18.5±1.3, with statistical difference (t=12.8354, P <0.05). The amplitude of accommodation of right eye was 8.9±2.5 D before training and was 15.1±1.2 D after training, with statistical difference (t=20.1624, P <0.05). The amplitude of accommodation of left eye was 8.6±2.2 D before training and was 15.3±1.1 D after training, with statistical difference (t=21.6218, P <0.05). \u0000 \u0000 \u0000Conclusions \u0000Visual training can effectively improve the adjust sensitivity and the amplitude of accommodation, uncorrected visual acuity and corrected visual acuity of low vision of no amblyopia. This suggests that the low vision of these patients is caused by dysfunction of accommodation. \u0000 \u0000 \u0000Key words: \u0000Visual training; Low vision; Amplitude of accommodation; Adjust sensitivity","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83739458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.013
Jiaying Wang, Chenhao Yang, Li Shen
Objective To observe the clinical efficacy of Toric design orthokeratology for myopia adolescents with moderate to high astigmatism. Methods A retrospective study. Twenty-four patients (40 eyes, Spherical group), were fitted with spherical orthokeratology lenses and 11 patients (18eyes, Toric group), were fitted with Toric design orthokeratology. Comparison of two groups 1 year eye axis of two different design orthokeratology. Patients fitted with Toric design orthokeratology lenses were measured uncorrected visual acuity (UCVA), corneal astigmatism and mean corneal curvature before lens wear and after wearing the lenses for 1 week, 1 month, 6 months, and 1 year. The relationship among the orthokeratology alignment zones curvature, flat K, corneal curvature with corneal diameter 5mm, 4mm place were analyzed. Date was analyzed with paired t test, independent samples t test and one-way ANOVA. Results After I year, AL increased by 0.25±0.14 (mm), 0.23±0.28 (mm) in the Spherical group and Toric group, indicating a statistically significant difference compared with those lens wear (t=-10.868, P 0.05). The uncorrected visual acuity (UCVA) had a statistically significant difference compared with UCVA before lens wear (F=83.185, P 0.05). Average corneal curvature had a statistically significant difference before and after lens wear (P 0.05), while had statistically significant difference with 5mm corneal diameter curvature (P <0.05). Conclusions Toric design and spherical design orthokeratology have similar effects in AL control with adolescents. Toric design orthokeratology can be fitted on myopic patients with moderate-to-high corneal astigmatism, and can improve the UCVA, reduce the corneal curvature, effectively and safely. Key words: Toric design Othokeratology; Corneal astigmatism; Myopia; Axial length
目的观察环面形角膜塑形镜治疗青少年中度至高度散光近视的临床疗效。方法回顾性研究。24例患者(40眼，球形组)配戴球形角膜塑形镜，11例患者(18眼，Toric组)配戴Toric设计角膜塑形镜。两组1年眼轴两种不同设计角膜塑形术的比较。配戴Toric设计角膜塑形镜的患者在配戴前、配戴1周、1个月、6个月和1年后分别测量非矫正视力(UCVA)、角膜散光和平均角膜曲率。分析角膜塑形对准区曲率、平面K、角膜曲率与角膜直径5mm、4mm位置的关系。数据分析采用配对t检验、独立样本t检验和单因素方差分析。结果1年后，球面组和托力组AL分别升高0.25±0.14 (mm)、0.23±0.28 (mm)，与晶状体磨损组比较差异有统计学意义(t=-10.868, P < 0.05)。未矫正视力(UCVA)与配戴前比较，差异有统计学意义(F=83.185, p0.05)。晶状体佩戴前后平均角膜曲率差异有统计学意义(P <0.05)，角膜直径5mm曲率差异有统计学意义(P <0.05)。结论环形角膜塑形术与球形角膜塑形术对青少年AL的控制效果相似。环形设计角膜塑形镜可用于角膜中高散光的近视患者，并能有效、安全地改善UCVA，降低角膜曲率。关键词:环形设计;眼角膜学;角膜散光;近视;轴向长度
{"title":"Clinical efficacy observation of Toric orthokeratology in myopic adolescent with moderate to high astigmatism for 1 year","authors":"Jiaying Wang, Chenhao Yang, Li Shen","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.013","url":null,"abstract":"Objective \u0000To observe the clinical efficacy of Toric design orthokeratology for myopia adolescents with moderate to high astigmatism. \u0000 \u0000 \u0000Methods \u0000A retrospective study. Twenty-four patients (40 eyes, Spherical group), were fitted with spherical orthokeratology lenses and 11 patients (18eyes, Toric group), were fitted with Toric design orthokeratology. Comparison of two groups 1 year eye axis of two different design orthokeratology. Patients fitted with Toric design orthokeratology lenses were measured uncorrected visual acuity (UCVA), corneal astigmatism and mean corneal curvature before lens wear and after wearing the lenses for 1 week, 1 month, 6 months, and 1 year. The relationship among the orthokeratology alignment zones curvature, flat K, corneal curvature with corneal diameter 5mm, 4mm place were analyzed. Date was analyzed with paired t test, independent samples t test and one-way ANOVA. \u0000 \u0000 \u0000Results \u0000After I year, AL increased by 0.25±0.14 (mm), 0.23±0.28 (mm) in the Spherical group and Toric group, indicating a statistically significant difference compared with those lens wear (t=-10.868, P 0.05). The uncorrected visual acuity (UCVA) had a statistically significant difference compared with UCVA before lens wear (F=83.185, P 0.05). Average corneal curvature had a statistically significant difference before and after lens wear (P 0.05), while had statistically significant difference with 5mm corneal diameter curvature (P <0.05). \u0000 \u0000 \u0000Conclusions \u0000Toric design and spherical design orthokeratology have similar effects in AL control with adolescents. Toric design orthokeratology can be fitted on myopic patients with moderate-to-high corneal astigmatism, and can improve the UCVA, reduce the corneal curvature, effectively and safely. \u0000 \u0000 \u0000Key words: \u0000Toric design Othokeratology; Corneal astigmatism; Myopia; Axial length","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78901272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.005
Xian-li Zhuang, Haoyu Wang, Lin Zhao, Bing-zhen Li, K. Feng
Objective To compare the efficacy of intravitreal bevacizumab (IVB) in the treatment of macular edema, with or without foveal hemorrhage within the foveal cystoid apaces, subretinal hemorrhage (SRH) and serous retinal detachment (SRD) resulting from branch retinal vein occlusion (BRVO). Methods A retrospective review of 33 consecutive patients (33 eyes) was conducted with ME caused by acute BRVO. All patients received a comprehensive ophthalmologic examination, including measurement of best-corrected visual acuity (BCVA), measurement of intraocular pressure, slit-lamp biomicroscopy, color fundus photograghy, fluorescein angiography, and spectral domain optical coherence tomography (SD-OCT). Using hemorrhage within the foveal cystoid apaces, subretinal hemorrhage (SRH) and serous retinal detachment (SRD) three factors, the multiple logistic model were developed. Results Foveal SRH was closely correlated with BCVA. Patients were classified into one of two groups depending on whether or not foveal SRH was detected at the initial visit, BCVA and central macular thickness (CMT) were observed. After 6 months, SD-OCT revealed serous reti-nal detachments in the fovea of 15 eyes, 10 of which had accompanying foveal SRH. Based on initial detection of foveal SRH, patients were divided into SRH-negative (23 eyes) or SRH-positive (10 eyes) groups. Initial BCVA did not differ between the two groups. In the SRH-negative group, both BCVA and CMT improved significantly after IVB injections (mean, 2.3 injections) at the 6-months follow-up examination. In the SRH-positive group, there was no significant improvement in BCVA after IVB injections (mean, 2.0 injections), although there was a significant decrease in CMT. The final BCVA of the SRH-positive group was significantly poorer than that of the SRH-negative group (P=0.001). Conclusions The presence of foveal SRH may be a negative predictor of IVB treatment outcomes for BRVO patients with ME. Key words: Branch retinal vein occlusion; Hemorrhage within the foveal cystoid apaces; Serous retinal detachment; Subretinal hemorrhage; Macular edema; Bevacizumab
{"title":"Intravitreal Bevacizumab treatment for branch retinal vein occlusion accompanied by macular edema","authors":"Xian-li Zhuang, Haoyu Wang, Lin Zhao, Bing-zhen Li, K. Feng","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.005","url":null,"abstract":"Objective \u0000To compare the efficacy of intravitreal bevacizumab (IVB) in the treatment of macular edema, with or without foveal hemorrhage within the foveal cystoid apaces, subretinal hemorrhage (SRH) and serous retinal detachment (SRD) resulting from branch retinal vein occlusion (BRVO). \u0000 \u0000 \u0000Methods \u0000A retrospective review of 33 consecutive patients (33 eyes) was conducted with ME caused by acute BRVO. All patients received a comprehensive ophthalmologic examination, including measurement of best-corrected visual acuity (BCVA), measurement of intraocular pressure, slit-lamp biomicroscopy, color fundus photograghy, fluorescein angiography, and spectral domain optical coherence tomography (SD-OCT). Using hemorrhage within the foveal cystoid apaces, subretinal hemorrhage (SRH) and serous retinal detachment (SRD) three factors, the multiple logistic model were developed. \u0000 \u0000 \u0000Results \u0000Foveal SRH was closely correlated with BCVA. Patients were classified into one of two groups depending on whether or not foveal SRH was detected at the initial visit, BCVA and central macular thickness (CMT) were observed. After 6 months, SD-OCT revealed serous reti-nal detachments in the fovea of 15 eyes, 10 of which had accompanying foveal SRH. Based on initial detection of foveal SRH, patients were divided into SRH-negative (23 eyes) or SRH-positive (10 eyes) groups. Initial BCVA did not differ between the two groups. In the SRH-negative group, both BCVA and CMT improved significantly after IVB injections (mean, 2.3 injections) at the 6-months follow-up examination. In the SRH-positive group, there was no significant improvement in BCVA after IVB injections (mean, 2.0 injections), although there was a significant decrease in CMT. The final BCVA of the SRH-positive group was significantly poorer than that of the SRH-negative group (P=0.001). \u0000 \u0000 \u0000Conclusions \u0000The presence of foveal SRH may be a negative predictor of IVB treatment outcomes for BRVO patients with ME. \u0000 \u0000 \u0000Key words: \u0000Branch retinal vein occlusion; Hemorrhage within the foveal cystoid apaces; Serous retinal detachment; Subretinal hemorrhage; Macular edema; Bevacizumab","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87460779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.003
Peng-wei Li
Objective To explore the relationship of serum retinol binding protein 4 (RBP4) with type 2 diabetic retinopathy. Methods Clinical case control study. The 83 cases of hospitalized pa-tients with type 2 diabetes mellitus (T2DM) were divided into three groups: PDR group (n =32 fun-dus examination showed proliferative diabetic retinopathy), NPDR group (n =20 fundus examination showed non proliferative diabetic retinopathy), NDR group (n =31 fundus examination showed nor-mal). Their serum RBP4 levels were measured. At the same time, factors that may be closely relat-ed to the occurrence and development of DR were detected. And we also measured the amplitude of B wave in full field electroretinogram (F-ERG). Results Serum RBP4 differences among three groups had statistical significance, P <0.05; There was significant difference in B wave amplitude among the three groups, P <0.05. Simple correlation analysis showed that the serum RBP4 level was negatively correlated with the b wave amplitude of ERG (r =-0.458, P =0.0001). Binary Logistic regres-sion analysis showed that RBP4 was significantly correlated with DR (B =0.105, P =0.019). Conclusions The increase of serum RBP4 level is consistent with the progress of DR. There is a close rela-tionship between serum RBP4 and the damage of retinal bipolar cells. Key words: Type 2 diabetes mellitus; Diabetic retinopathy; Retinol binding protein 4; Full-Field Electroretinograms
目的探讨血清视黄醇结合蛋白4 (RBP4)与2型糖尿病视网膜病变的关系。方法临床病例对照研究。将83例住院2型糖尿病(T2DM)患者分为3组:PDR组(32例眼底检查显示增殖性糖尿病视网膜病变)、NPDR组(20例眼底检查显示非增殖性糖尿病视网膜病变)、NDR组(31例眼底检查正常)。测定血清RBP4水平。同时，检测可能与DR发生发展密切相关的因素。并在全视场视网膜电图(F-ERG)中测量B波振幅。结果三组间血清RBP4差异有统计学意义，P <0.05;三组患者B波振幅差异有统计学意义，P <0.05。简单相关分析显示，血清RBP4水平与ERG b波振幅呈负相关(r =-0.458, P =0.0001)。二元Logistic回归分析显示RBP4与DR显著相关(B =0.105, P =0.019)。结论血清RBP4水平的升高与dr的进展一致，血清RBP4与视网膜双极细胞损伤有密切关系。关键词:2型糖尿病;糖尿病视网膜病变;视黄醇结合蛋白4;细致的视网膜电流图
{"title":"Clinical correlation research of serum retinol binding protein 4 and type 2 diabetic retinopathy","authors":"Peng-wei Li","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.003","url":null,"abstract":"Objective \u0000To explore the relationship of serum retinol binding protein 4 (RBP4) with type 2 diabetic retinopathy. \u0000 \u0000 \u0000Methods \u0000Clinical case control study. The 83 cases of hospitalized pa-tients with type 2 diabetes mellitus (T2DM) were divided into three groups: PDR group (n =32 fun-dus examination showed proliferative diabetic retinopathy), NPDR group (n =20 fundus examination showed non proliferative diabetic retinopathy), NDR group (n =31 fundus examination showed nor-mal). Their serum RBP4 levels were measured. At the same time, factors that may be closely relat-ed to the occurrence and development of DR were detected. And we also measured the amplitude of B wave in full field electroretinogram (F-ERG). \u0000 \u0000 \u0000Results \u0000Serum RBP4 differences among three groups had statistical significance, P <0.05; There was significant difference in B wave amplitude among the three groups, P <0.05. Simple correlation analysis showed that the serum RBP4 level was negatively correlated with the b wave amplitude of ERG (r =-0.458, P =0.0001). Binary Logistic regres-sion analysis showed that RBP4 was significantly correlated with DR (B =0.105, P =0.019). \u0000 \u0000 \u0000Conclusions \u0000The increase of serum RBP4 level is consistent with the progress of DR. There is a close rela-tionship between serum RBP4 and the damage of retinal bipolar cells. \u0000 \u0000 \u0000Key words: \u0000Type 2 diabetes mellitus; Diabetic retinopathy; Retinol binding protein 4; Full-Field Electroretinograms","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81557111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.08.018
Yong-Ming Shen, F. Zhu
Objective To compare the clinical significance of large and small spot YAG in Iridectomy before the Implantable Collamer Lens (ICL) implantation. Methods Seventy cases were randomly divided into group A and B, group A of 34 patients with large YAG spot iris peripheral laser (250um energy, the total energy 11-13mJ at the top 11 o’clock to 1 o’clock direction iris roots perforation of about 1×2mm) group B of 33 cases with small YAG spot iris peripheral laser (100um energy, the total energy 11-13mJ at the top 11 o’clock to 1 o’clock direction iris root perforation of about 1×2mm). Observation of intraocular pressure changes after laser surgery. Results Group A large spot and group B small spot get high intraocular pressure two hours later (Increased IOP 8 mmHg).There was no significant difference between the two groups, intraocular pressure increased 24 hours later (Increased intraocular pressure 8mmHg). Conclusions The small-spot YAG laser in the peripheral iridectomy produces iris depigmentation, causes inflammatory response, increase intraoc-ular pressure. The larger spot YAG laser iridotomy has advantages in hole forming of the iris peripheral edge, it has clinical significance to clinical iridal laser drilling, especially in patients with thicker iris stroma and more pigments. Key words: YAG laser; Peripheral iridectomy; Intraocular pressure
{"title":"Comparison of the size of YAG flare in implantable contact lens with intraocular lens implantation and peripheral iridectomy","authors":"Yong-Ming Shen, F. Zhu","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.08.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.08.018","url":null,"abstract":"Objective \u0000To compare the clinical significance of large and small spot YAG in Iridectomy before the Implantable Collamer Lens (ICL) implantation. \u0000 \u0000 \u0000Methods \u0000Seventy cases were randomly divided into group A and B, group A of 34 patients with large YAG spot iris peripheral laser (250um energy, the total energy 11-13mJ at the top 11 o’clock to 1 o’clock direction iris roots perforation of about 1×2mm) group B of 33 cases with small YAG spot iris peripheral laser (100um energy, the total energy 11-13mJ at the top 11 o’clock to 1 o’clock direction iris root perforation of about 1×2mm). Observation of intraocular pressure changes after laser surgery. \u0000 \u0000 \u0000Results \u0000Group A large spot and group B small spot get high intraocular pressure two hours later (Increased IOP 8 mmHg).There was no significant difference between the two groups, intraocular pressure increased 24 hours later (Increased intraocular pressure 8mmHg). \u0000 \u0000 \u0000Conclusions \u0000The small-spot YAG laser in the peripheral iridectomy produces iris depigmentation, causes inflammatory response, increase intraoc-ular pressure. The larger spot YAG laser iridotomy has advantages in hole forming of the iris peripheral edge, it has clinical significance to clinical iridal laser drilling, especially in patients with thicker iris stroma and more pigments. \u0000 \u0000 \u0000Key words: \u0000YAG laser; Peripheral iridectomy; Intraocular pressure","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72478095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.016
Xiaofei Guo, F. Xiao
Objective To observe the clinical treatment of anterior corneal stromal puncture combined with amniotic membrane patching in bullous keratopathy and rsistent epithelial defects and recurrent corneal erosion. Methods Retrospective case series study. Analysis retrospectively the treatment of bullous keratopathy in 39 cases, 40 eyes in Tangshan ophthalmic hospital from January 2013 to January 2016 which implement anterior corneal stromal puncture combined with amniotic membrane patching. Among them, in 26 cases with bullous keratopathy in 26 eyes including 7 eyes with cataract surgery for glaucoma, 3 eyes with absolute glaucoma period, 5 eyes with vitrectomy, 6 eyes with ocular trauma, 5 eyes with neovascular glaucoma. In 8 cases with rsistent epithelial defects in 8 eyes including 4 eyes with acid burn, 4 eyes with alkali bum. In 5 cases with recurrent corneal erosion in 6 eyes including 2 eyes with Lattice malnutrition, 4 eyes with ocular trauma, 16 cases with patients of diabetes. All patients had obvious pain, tears irritation symptom. When the treatment was invalid after conservative therapy. The anterior corneal stromal puncture combined with amniotic membrane patching was carried out, to observe the eye irritation, corneal epithelial healing,edema of matrix and postoperative visual acuity, and so on. Results Forty eyes in 39 cases were relieved 3 days after the surgery, all patients had no pain and irritation symptoms after amniotic suture removal in 7-10 days. The corneal epithelium was repaired under the slit lamp microscope. One month the bullous keratopathy was recurrence after operation. In one eye which was cured with second anterior corneal stromal puncture. Follow up for 3-6 months, there were no recurrence of keratopathy, corneal epithelium was smooth, no edema, corneal stromal puncture area shallow layer to form a layer of uniform opacitas. The postoperative visual acuity: 22 eyes had no change before and after operation, 18 eyes improved partly. Conclusions The bullous keratopathy patients, resistant epithelial defects and recurrent corneal erosion caused by various factors are treated with anterior corneal stromal puncture combined with amniotic membrane patching, the eye symptom is obviously improved. Not only save the eyeball, but also improve vision on some of the eye. The anterior corneal stromal puncture combined with amniotic membrane patching is a simple, effective and reliable treatment method. Key words: Anterior corneal stromal puncture; Keratopathy; Amniotic membrane patching
{"title":"The application of anterior corneal stromal puncture combined with amniotic membrane patching in corneal diseases","authors":"Xiaofei Guo, F. Xiao","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.016","url":null,"abstract":"Objective \u0000To observe the clinical treatment of anterior corneal stromal puncture combined with amniotic membrane patching in bullous keratopathy and rsistent epithelial defects and recurrent corneal erosion. \u0000 \u0000 \u0000Methods \u0000Retrospective case series study. Analysis retrospectively the treatment of bullous keratopathy in 39 cases, 40 eyes in Tangshan ophthalmic hospital from January 2013 to January 2016 which implement anterior corneal stromal puncture combined with amniotic membrane patching. Among them, in 26 cases with bullous keratopathy in 26 eyes including 7 eyes with cataract surgery for glaucoma, 3 eyes with absolute glaucoma period, 5 eyes with vitrectomy, 6 eyes with ocular trauma, 5 eyes with neovascular glaucoma. In 8 cases with rsistent epithelial defects in 8 eyes including 4 eyes with acid burn, 4 eyes with alkali bum. In 5 cases with recurrent corneal erosion in 6 eyes including 2 eyes with Lattice malnutrition, 4 eyes with ocular trauma, 16 cases with patients of diabetes. All patients had obvious pain, tears irritation symptom. When the treatment was invalid after conservative therapy. The anterior corneal stromal puncture combined with amniotic membrane patching was carried out, to observe the eye irritation, corneal epithelial healing,edema of matrix and postoperative visual acuity, and so on. \u0000 \u0000 \u0000Results \u0000Forty eyes in 39 cases were relieved 3 days after the surgery, all patients had no pain and irritation symptoms after amniotic suture removal in 7-10 days. The corneal epithelium was repaired under the slit lamp microscope. One month the bullous keratopathy was recurrence after operation. In one eye which was cured with second anterior corneal stromal puncture. Follow up for 3-6 months, there were no recurrence of keratopathy, corneal epithelium was smooth, no edema, corneal stromal puncture area shallow layer to form a layer of uniform opacitas. The postoperative visual acuity: 22 eyes had no change before and after operation, 18 eyes improved partly. \u0000 \u0000 \u0000Conclusions \u0000The bullous keratopathy patients, resistant epithelial defects and recurrent corneal erosion caused by various factors are treated with anterior corneal stromal puncture combined with amniotic membrane patching, the eye symptom is obviously improved. Not only save the eyeball, but also improve vision on some of the eye. The anterior corneal stromal puncture combined with amniotic membrane patching is a simple, effective and reliable treatment method. \u0000 \u0000 \u0000Key words: \u0000Anterior corneal stromal puncture; Keratopathy; Amniotic membrane patching","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73232445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.07.010
M. Pan, Mei Yang, Ren-yi Xie, Huan He, Haiyan Wang
Objective To study the influence of corneal protection on the ocular surface and its clinical significance in strabismus surgery. Methods Strabismus patients aged from 7 to 45 years old were collected and divided into 3 groups according to the difference of corneal protection. At different time points, the first noninvasive tear film break-up time, average noninvasive tear film break-up time, and tear meniscus height were measured and the cornea fluorescein staining was evaluated. On the first day after surgery, the symptom of photophobia was observed. Finally, all the data were analyzed by statistics. Results The tear film break-up time wasn’t influenced by the surgery. Against other two groups,the occurrence rate of the symptom of photophobia and the positive cornea fluorescein staining were lower in the group B. The tear meniscus height of the group B increased little at 1 day after surgery and decreased to the preoperative level at one week after surgery. Conclusions Protecting the cornea in strabismus surgery by the 2% hydroxypropyl methycellulose can make patients more comfortable after operation.It’s simple and meaningful to do this during the surgery. Key words: Corneal protection; Strabismus surgery; The cornea fluorescein staining; Photophobia
{"title":"The clinical significance of corneal protection to the ocular surface in strabismus surgery","authors":"M. Pan, Mei Yang, Ren-yi Xie, Huan He, Haiyan Wang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.07.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.07.010","url":null,"abstract":"Objective \u0000To study the influence of corneal protection on the ocular surface and its clinical significance in strabismus surgery. \u0000 \u0000 \u0000Methods \u0000Strabismus patients aged from 7 to 45 years old were collected and divided into 3 groups according to the difference of corneal protection. At different time points, the first noninvasive tear film break-up time, average noninvasive tear film break-up time, and tear meniscus height were measured and the cornea fluorescein staining was evaluated. On the first day after surgery, the symptom of photophobia was observed. Finally, all the data were analyzed by statistics. \u0000 \u0000 \u0000Results \u0000The tear film break-up time wasn’t influenced by the surgery. Against other two groups,the occurrence rate of the symptom of photophobia and the positive cornea fluorescein staining were lower in the group B. The tear meniscus height of the group B increased little at 1 day after surgery and decreased to the preoperative level at one week after surgery. \u0000 \u0000 \u0000Conclusions \u0000Protecting the cornea in strabismus surgery by the 2% hydroxypropyl methycellulose can make patients more comfortable after operation.It’s simple and meaningful to do this during the surgery. \u0000 \u0000 \u0000Key words: \u0000Corneal protection; Strabismus surgery; The cornea fluorescein staining; Photophobia","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89201114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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