Pub Date : 2017-05-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.05.008
Weiwei Liu, Ke Zhang
Objective To investigate the expression of cyclooxygenase(cox)-2 and matrix metalloproteinase (MMP)-9 in lacrimal gland epithelical tumors and the relations between pathology and clinic prognosis. Methods The samples were selected from lacrimal glands of 29 cases of ACC, 37cases of PA and 8 cases adjacent normaltissues. Expression of COX-2 and MMP-9 were detected by immunohistochemistry and then the clinical significance was analyzed. Results No expression of COX-2 or MMP-9 were detected in adjacent normal lacrimal glands. The level of COX-2 and MMP-9 expressed in ACC group were both higher than those in PA group (P <0.05). There was positive correlation between expression of COX-2 and MMP-9 (P <0.01).Significant differences in the risk of recurrence between positive and negative expression of COX-2 and MMP-9 were both noted (P <0.05). Conclusions COX-2 and MMP-9 may be closely related to the prognosis of patients. They can be considered as joint markers to be applied to predict the recurrent risk and to develop the treatment plan. Key words: Pleomorphicadenoma; adenoid cystic carcinoma; Cyclooxygenase-2; Matrix metalloproteninase-9; Prognosis
{"title":"Expression of COX-2 and MMP-9 in lacrimal gland epithelical tumors and significance to prognosis","authors":"Weiwei Liu, Ke Zhang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.05.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.05.008","url":null,"abstract":"Objective \u0000To investigate the expression of cyclooxygenase(cox)-2 and matrix metalloproteinase (MMP)-9 in lacrimal gland epithelical tumors and the relations between pathology and clinic prognosis. \u0000 \u0000 \u0000Methods \u0000The samples were selected from lacrimal glands of 29 cases of ACC, 37cases of PA and 8 cases adjacent normaltissues. Expression of COX-2 and MMP-9 were detected by immunohistochemistry and then the clinical significance was analyzed. \u0000 \u0000 \u0000Results \u0000No expression of COX-2 or MMP-9 were detected in adjacent normal lacrimal glands. The level of COX-2 and MMP-9 expressed in ACC group were both higher than those in PA group (P <0.05). There was positive correlation between expression of COX-2 and MMP-9 (P <0.01).Significant differences in the risk of recurrence between positive and negative expression of COX-2 and MMP-9 were both noted (P <0.05). \u0000 \u0000 \u0000Conclusions \u0000COX-2 and MMP-9 may be closely related to the prognosis of patients. They can be considered as joint markers to be applied to predict the recurrent risk and to develop the treatment plan. \u0000 \u0000 \u0000Key words: \u0000Pleomorphicadenoma; adenoid cystic carcinoma; Cyclooxygenase-2; Matrix metalloproteninase-9; Prognosis","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86363698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.05.023
Dandan Su, Jiusheng Zheng
Objective To identify the relationship between the degree of lens opacity and the hardness of nuclear and the protein expression level of 20s proteasome α2 subunit in age-related cataract patients. Methods Phacoemulsification or small incision cataract extraction was performed in 120 cases (60 cases of nuclear and 60 cases of cortical) and collected these anterior capsules. According to the degree of hardness and opacity of the lens nucleus, the nucleus was divided into group A: young nucleus, group B: old nuclear; cortical was divided into group A: mild opacity, group B: severe haze. Two types of cataract in group A, group B; and Western-blot was used to determine the 20s proteasome subunit alpha 2 expression levels in two groups of patients with ARC in the anterior lens capsule; experimental research work from July 2015 to March 2016. Results Compared with group A, the group B, 20s proteasome subunit α2 expression levels were significantly lower (nuclear (0.99±0.02) VS (0.58±0.08) P <0.01, cortical (1.26±0.15) VS (0.89±0.09), P <0.05, with the degree of lens opacity and nuclear hardness with the 20s proteasome α2 subunit content in age-related cataract patients was negatively correlated. Conclusions The protein expression levels of 20s protein α2 subunit in the anterior capsule of age-related cataract patients decrease with the degree of lens opacity and the hardness of the nucleus. Key words: Age-related cataract; 20s proteasome α2 subunit; Ubiquitin proteasome pathway; Anterior capsule
{"title":"Expression and significance of α2 subunit of 20s proteasome in anterior capsule of lens in patients with age-related cataract","authors":"Dandan Su, Jiusheng Zheng","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.05.023","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.05.023","url":null,"abstract":"Objective \u0000To identify the relationship between the degree of lens opacity and the hardness of nuclear and the protein expression level of 20s proteasome α2 subunit in age-related cataract patients. \u0000 \u0000 \u0000Methods \u0000Phacoemulsification or small incision cataract extraction was performed in 120 cases (60 cases of nuclear and 60 cases of cortical) and collected these anterior capsules. According to the degree of hardness and opacity of the lens nucleus, the nucleus was divided into group A: young nucleus, group B: old nuclear; cortical was divided into group A: mild opacity, group B: severe haze. Two types of cataract in group A, group B; and Western-blot was used to determine the 20s proteasome subunit alpha 2 expression levels in two groups of patients with ARC in the anterior lens capsule; experimental research work from July 2015 to March 2016. \u0000 \u0000 \u0000Results \u0000Compared with group A, the group B, 20s proteasome subunit α2 expression levels were significantly lower (nuclear (0.99±0.02) VS (0.58±0.08) P <0.01, cortical (1.26±0.15) VS (0.89±0.09), P <0.05, with the degree of lens opacity and nuclear hardness with the 20s proteasome α2 subunit content in age-related cataract patients was negatively correlated. \u0000 \u0000 \u0000Conclusions \u0000The protein expression levels of 20s protein α2 subunit in the anterior capsule of age-related cataract patients decrease with the degree of lens opacity and the hardness of the nucleus. \u0000 \u0000 \u0000Key words: \u0000Age-related cataract; 20s proteasome α2 subunit; Ubiquitin proteasome pathway; Anterior capsule","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76591414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.018
Hao Tang, Lan-Hua Shen
Objective TTo study the fracture finding methods and inferior lacrimal canaliculus anastomosis techniques, choosing the right duct support tubes to improve success rate of anastomosis of the disrupted canaliculus in emergency. Methods Directly under the microscope, looking for broken ends of the lateral inferior lacrimal canaliculus fracture, using extradural catheter new RS for support broken lacrimal duct ends by anastomosis of lacrimal canal. Results Of 128 tears tubular break (112 cases of the lower disrupted canaliculus, 16 upper disrupted canaliculus), 125 cases were anastomosis successfully, 3 cases could not find lacrimal sac while using open retrograde intubation with success. Conclusions It is a simple, easy, reliable and worth promoting method for anastomosis of broken lachrymal canaliculus. Key words: Ruptured inferior lacrimal; Anastomosis; Microscope; New RS lacrimal canal; Epidural catheter
{"title":"Operative technique and clinical observation of anastomosis for disrupted canaliculus","authors":"Hao Tang, Lan-Hua Shen","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.018","url":null,"abstract":"Objective \u0000TTo study the fracture finding methods and inferior lacrimal canaliculus anastomosis techniques, choosing the right duct support tubes to improve success rate of anastomosis of the disrupted canaliculus in emergency. \u0000 \u0000 \u0000Methods \u0000Directly under the microscope, looking for broken ends of the lateral inferior lacrimal canaliculus fracture, using extradural catheter new RS for support broken lacrimal duct ends by anastomosis of lacrimal canal. \u0000 \u0000 \u0000Results \u0000Of 128 tears tubular break (112 cases of the lower disrupted canaliculus, 16 upper disrupted canaliculus), 125 cases were anastomosis successfully, 3 cases could not find lacrimal sac while using open retrograde intubation with success. \u0000 \u0000 \u0000Conclusions \u0000It is a simple, easy, reliable and worth promoting method for anastomosis of broken lachrymal canaliculus. \u0000 \u0000 \u0000Key words: \u0000Ruptured inferior lacrimal; Anastomosis; Microscope; New RS lacrimal canal; Epidural catheter","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85906157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.009
Rong Lu, Jing Lin
Objective To analyze the effect of shoelace continuous suture for conjunctival incision on preventing postsurgical shallow anterior chamber. Methods Forty-one patients (82 eyes) diagnosed as primary glaucoma, and treated with trabeculectomy were included in this study during the period from March 2011 to March 2016. One eye, which was randomly chosen and applied shoelace continuous suture to attach the conjuctival fornix flap to the cornea, was included in observation group; the other eye, which under went same surgical procedure but applied conjuctival interrupted suture, was included in the control group. Intraocular pressure (IOP) and anterior chamber depth was measured and recorded after 3 days, 1 week and 1 month after surgery. Results Among the observation group, 3 days after surgery, IOP of 38 eyes was successfully controlled, IOP of 3 eyes was partially successfully controlled, with control rate as 100%; 1 week and 1 month after surgery, IOP of 37 eyes was successfully controlled, IOP of 3 eyes was partially successfully controlled, IOP of 1 eye was failed to control, with control rate as 97.56%. Among the control group, 3 days after surgery, IOP of 39 eyes was successfully controlled, IOP of 2 eyes was partially successfully controlled, with control rate as 100%; 1 week after surgery, IOP of 38 eyes was successfully controlled, IOP of 2 eyes was partially successfully controlled, IOP of 1 eye was failed to control, with control rate as 97.56%; 1 month after surgery, IOP of 37 eyes was successfully controlled, IOP of 2 eyes was partially successfully controlled, IOP of 2 eye was failed to control, with control rate as 95.12%. No significant difference was observed between two groups (P >0.05). Six eyes (6/41, 14.63%) had I degree shallow anterior chamber 3 days after surgery among the observation group, all recovered within 1 week without treatment, and remained stabilized 1 month after surgery; 12 eyes with shallow anterior chamber after surgery occurred in control group (12/41, 29.26%), significantly more than the observe group (χ2=18.76, P <0.01). Among them, 6 eyes had I degree shallow anterior chamber, 4 II degree shallow anterior chamber, and 1 III degree shallow anterior chamber. There were significantly more II and III degree shallow anterior chamber occurred in the control group (5/41, 12.19%) than observe group (0/41) (χ2=24.4, P <0.01). Eyes in the control group were recovered within 1-2 week after treatment, and stabilized after that. Conclusions Shoelace continu-ous suture for conjunctival incision can help preventing early stage postsurgical shallow anterior chamber. Key words: Shoelace continuous suture; Trabeculectomy; Anterior chamber
目的分析结膜切口鞋带连续缝合对预防术后浅前房的效果。方法选取2011年3月至2016年3月间行青光眼小梁切除术的原发性青光眼患者41例(82眼)。随机选取1只眼,用鞋带连续缝合将结缔组织瓣贴附于角膜上,作为观察组;另一只眼采用相同的手术方法,但采用结缔组织间断缝合,作为对照组。术后3天、1周、1个月测量眼压(IOP)和前房深度。结果观察组患者术后3 d眼压控制成功38眼,部分眼压控制成功3眼,控制率100%;术后1周和1个月,眼压控制成功37眼,部分控制成功3眼,眼压控制失败1眼,控制率为97.56%。对照组术后3 d成功控制眼压39眼,部分控制眼压2眼,控制率100%;术后1周,眼压控制成功38眼,部分控制成功2眼,未能控制1眼,控制率为97.56%;术后1个月,成功控制眼压37眼,部分控制眼压2眼,未能控制眼压2眼,控制率95.12%。两组间差异无统计学意义(P >0.05)。观察组6只眼(6/41,14.63%)术后3 d出现I度浅前房,均在1周内恢复,无需治疗,术后1个月病情稳定;对照组术后出现浅前房12眼(12/41,29.26%),明显多于观察组(χ2=18.76, P <0.01)。其中,I度浅前房6只眼,II度浅前房4只眼,III度浅前房1只眼。对照组II、III度浅前房发生率(5/41,12.19%)明显高于观察组(0/41)(χ2=24.4, P <0.01)。对照组患者治疗后1 ~ 2周眼恢复,术后稳定。结论结膜切口鞋带连续缝合可预防术后早期浅前房。关键词:鞋带连续缝合;小梁切除术;前房
{"title":"Analysis of the effect of shoelace continuous suture for conjunctival incision on preventing postsurgical shallow anterior chamber","authors":"Rong Lu, Jing Lin","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.009","url":null,"abstract":"Objective \u0000To analyze the effect of shoelace continuous suture for conjunctival incision on preventing postsurgical shallow anterior chamber. \u0000 \u0000 \u0000Methods \u0000Forty-one patients (82 eyes) diagnosed as primary glaucoma, and treated with trabeculectomy were included in this study during the period from March 2011 to March 2016. One eye, which was randomly chosen and applied shoelace continuous suture to attach the conjuctival fornix flap to the cornea, was included in observation group; the other eye, which under went same surgical procedure but applied conjuctival interrupted suture, was included in the control group. Intraocular pressure (IOP) and anterior chamber depth was measured and recorded after 3 days, 1 week and 1 month after surgery. \u0000 \u0000 \u0000Results \u0000Among the observation group, 3 days after surgery, IOP of 38 eyes was successfully controlled, IOP of 3 eyes was partially successfully controlled, with control rate as 100%; 1 week and 1 month after surgery, IOP of 37 eyes was successfully controlled, IOP of 3 eyes was partially successfully controlled, IOP of 1 eye was failed to control, with control rate as 97.56%. Among the control group, 3 days after surgery, IOP of 39 eyes was successfully controlled, IOP of 2 eyes was partially successfully controlled, with control rate as 100%; 1 week after surgery, IOP of 38 eyes was successfully controlled, IOP of 2 eyes was partially successfully controlled, IOP of 1 eye was failed to control, with control rate as 97.56%; 1 month after surgery, IOP of 37 eyes was successfully controlled, IOP of 2 eyes was partially successfully controlled, IOP of 2 eye was failed to control, with control rate as 95.12%. No significant difference was observed between two groups (P >0.05). Six eyes (6/41, 14.63%) had I degree shallow anterior chamber 3 days after surgery among the observation group, all recovered within 1 week without treatment, and remained stabilized 1 month after surgery; 12 eyes with shallow anterior chamber after surgery occurred in control group (12/41, 29.26%), significantly more than the observe group (χ2=18.76, P <0.01). Among them, 6 eyes had I degree shallow anterior chamber, 4 II degree shallow anterior chamber, and 1 III degree shallow anterior chamber. There were significantly more II and III degree shallow anterior chamber occurred in the control group (5/41, 12.19%) than observe group (0/41) (χ2=24.4, P <0.01). Eyes in the control group were recovered within 1-2 week after treatment, and stabilized after that. \u0000 \u0000 \u0000Conclusions \u0000Shoelace continu-ous suture for conjunctival incision can help preventing early stage postsurgical shallow anterior chamber. \u0000 \u0000 \u0000Key words: \u0000Shoelace continuous suture; Trabeculectomy; Anterior chamber","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87495239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.005
Kangning Li, Zhiling Song, Chaojuan Ju
Objective To analyze the relationship between the average corneal curvature and the difference of intraocular lens (IOL)on both sides of the short eye axis. Methods Prospective study of corneal curvature on randomly collected 500 corneas of normal adult cataract patients. With the same corneal curvature, 177 cases of corneal curvature were obtained; the average of 177 cases of corneal curvature was obtained, the range of the average corneal curvature was 40.125-48.375D. In the range of average corneal curvature, according to the calculated critical axial length (21.97-22.02mm), the difference of IOL was obtained. The correlation on intraocular lens of difference and average corneal curvature were analyzed. Results There was a negative correlation between the difference of intraocular lens and the average corneal curvature in critical axial of short axis r=-0.968, P=0.000. Conclusions In normal adult cataract patients with normal corneal, the difference of intraocular lens number gradually becomes smaller with the increase of average corneal curvature. Key words: Corneal curvature; Short axis; Intraocular lens; Cataract
{"title":"Effect of corneal curvature on the difference of intraocular lens in short eye axis","authors":"Kangning Li, Zhiling Song, Chaojuan Ju","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.005","url":null,"abstract":"Objective \u0000To analyze the relationship between the average corneal curvature and the difference of intraocular lens (IOL)on both sides of the short eye axis. \u0000 \u0000 \u0000Methods \u0000Prospective study of corneal curvature on randomly collected 500 corneas of normal adult cataract patients. With the same corneal curvature, 177 cases of corneal curvature were obtained; the average of 177 cases of corneal curvature was obtained, the range of the average corneal curvature was 40.125-48.375D. In the range of average corneal curvature, according to the calculated critical axial length (21.97-22.02mm), the difference of IOL was obtained. The correlation on intraocular lens of difference and average corneal curvature were analyzed. \u0000 \u0000 \u0000Results \u0000There was a negative correlation between the difference of intraocular lens and the average corneal curvature in critical axial of short axis r=-0.968, P=0.000. \u0000 \u0000 \u0000Conclusions \u0000In normal adult cataract patients with normal corneal, the difference of intraocular lens number gradually becomes smaller with the increase of average corneal curvature. \u0000 \u0000 \u0000Key words: \u0000Corneal curvature; Short axis; Intraocular lens; Cataract","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78691309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.014
Zhe Guo
Objective To explore the surgical approach of glaucoma combined with cataract and to observe its long-term clinical effect. Methods A total of 157 patients (183 eyes) with glaucoma combined with cataract were selected. Among them, 123 cases (131 eyes) of cataract were found by glaucoma admission, 34 cases (52 eyes) of glaucoma were found by cataract admission. There were 78 cases (87 eyes) of primary acute angle-closure glaucoma, 32 cases (47 eyes) of primary chronic angle-closure glau-coma, 3 cases (4 eyes) of primary open-angle glaucoma, cataract secondary glaucoma in 21 cases (21 eyes), residual glaucoma complicated with cataract in 23 cases (24 eyes). According to the cause of the disease, the course of disease, the degree of angle closure to choose different surgical methods, follow-up > 6 months to observe the treatment effect. Results Of 37 patients (41 eyes) underwent cataract surgery combined with glaucoma surgery (22.4%), 62 patients (73 eyes) underwent cataract surgery (39.9%) and 58 patients (69 eyes) underwent glaucoma surgery (37.7%). The intraocular pressure control was satisfactory in 136 cases (171 eyes, 93.4%) by not using or using 1-2 kinds of local reduction of intraocular pressure drugs, 11 cases (12 eyes, 6.6%) underwent secondary anti-glaucoma surgery. No serious complications occurred. Conclusions Various surgery approach for glaucoma with a cataract should be chosen depending on the different conditions. The success rate of operation should be improved to the maximum extent and the pain of the patients should be alleviated. Key words: Cataract secondary glaucoma; Clinical effect; Operation method; Residual glaucoma; Angle separation
{"title":"Observation of the surgical options and long-term effect of cataract combined with glaucoma","authors":"Zhe Guo","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.014","url":null,"abstract":"Objective \u0000To explore the surgical approach of glaucoma combined with cataract and to observe its long-term clinical effect. \u0000 \u0000 \u0000Methods \u0000A total of 157 patients (183 eyes) with glaucoma combined with cataract were selected. Among them, 123 cases (131 eyes) of cataract were found by glaucoma admission, 34 cases (52 eyes) of glaucoma were found by cataract admission. There were 78 cases (87 eyes) of primary acute angle-closure glaucoma, 32 cases (47 eyes) of primary chronic angle-closure glau-coma, 3 cases (4 eyes) of primary open-angle glaucoma, cataract secondary glaucoma in 21 cases (21 eyes), residual glaucoma complicated with cataract in 23 cases (24 eyes). According to the cause of the disease, the course of disease, the degree of angle closure to choose different surgical methods, follow-up > 6 months to observe the treatment effect. \u0000 \u0000 \u0000Results \u0000Of 37 patients (41 eyes) underwent cataract surgery combined with glaucoma surgery (22.4%), 62 patients (73 eyes) underwent cataract surgery (39.9%) and 58 patients (69 eyes) underwent glaucoma surgery (37.7%). The intraocular pressure control was satisfactory in 136 cases (171 eyes, 93.4%) by not using or using 1-2 kinds of local reduction of intraocular pressure drugs, 11 cases (12 eyes, 6.6%) underwent secondary anti-glaucoma surgery. No serious complications occurred. \u0000 \u0000 \u0000Conclusions \u0000Various surgery approach for glaucoma with a cataract should be chosen depending on the different conditions. The success rate of operation should be improved to the maximum extent and the pain of the patients should be alleviated. \u0000 \u0000 \u0000Key words: \u0000Cataract secondary glaucoma; Clinical effect; Operation method; Residual glaucoma; Angle separation","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82222743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.006
Guohua Wang
Objective To compare the changes in tear film after Microincision coaxial cataract surgery with different direction of clear cornea incisions with Keratograph 4. Methods A clinical case-control study. One hundred and forty-two patients (142 eyes) with age-related cataract were di-vided into two groups according to the surgical approach. Non-invasive tear break time (NIBUT), tear meniscus height, schirmer I test and subjective score for dryness were compared between two groups. Results One day, 7 days and 1 month postoperatively, both the mean NIBUT and tear meniscus height of the clear cornea incision above margin group reduced greatly than the clear corneaincision margin level group. The differences among two groups had significance statistically (Fgroup diff=7577.541, P <0.01; F group diff=9523.241, P <0.01). The values recovered to preoperative levels at 3 months postoperatively and there was no statistically significant difference among the two groups. At 1 day, 7 days, 1 month and 3 months postoperatively, the mean subjective scores for dryness of the a clear cornea incision margin level group were higher than the clear cornea incision above margin group; and a statistically significant difference among the two groups (F group diff=6781.533, P <0.01). All of the values recovered to preoperative levels at 3 months postoperatively. Conclusions A clear cornea incision above margin phacoemulsification bring less disturbance to ocular surface, brighter symptoms of dry eye and the patients feel more comfortable. Key words: Microincision coaxial cataract surgery; A clear cornea incision above margin; A clear cornea incision margin level; Tear film; Dryness
目的比较不同方向角膜透明切口的微切口同轴白内障术后泪膜的变化。方法采用临床病例-对照研究。将142只眼的老年性白内障患者按手术入路分为两组。比较两组无创撕裂破裂时间(NIBUT)、撕裂半月板高度、schirmer I测试及干爽主观评分。结果术后1天、7天和1个月,角膜缘以上透明切口组的平均NIBUT和撕裂半月板高度均明显低于角膜缘以上透明切口组。两组间差异有统计学意义(f组差异=7577.541,P <0.01;F组diff=9523.241, P <0.01)。术后3个月恢复至术前水平,两组比较差异无统计学意义。术后1天、7天、1个月、3个月,角膜切口边缘水平组干性主观评分平均值高于切口边缘以上组;两组间差异有统计学意义(F组差异=6781.533,P <0.01)。术后3个月,各项指标均恢复到术前水平。结论角膜缘以上切口清晰的超声乳化术对眼表的干扰小,干眼症状明显,患者感觉舒适。关键词:微切口白内障手术;边缘上有一个清晰的角膜切口;角膜切口边缘水平清晰;泪液膜;干燥
{"title":"Analysis on tear film after phacoemul sification with different direction of clear cornea incisions with Keratograph 4","authors":"Guohua Wang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.006","url":null,"abstract":"Objective \u0000To compare the changes in tear film after Microincision coaxial cataract surgery with different direction of clear cornea incisions with Keratograph 4. \u0000 \u0000 \u0000Methods \u0000A clinical case-control study. One hundred and forty-two patients (142 eyes) with age-related cataract were di-vided into two groups according to the surgical approach. Non-invasive tear break time (NIBUT), tear meniscus height, schirmer I test and subjective score for dryness were compared between two groups. \u0000 \u0000 \u0000Results \u0000One day, 7 days and 1 month postoperatively, both the mean NIBUT and tear meniscus height of the clear cornea incision above margin group reduced greatly than the clear corneaincision margin level group. The differences among two groups had significance statistically (Fgroup diff=7577.541, P <0.01; F group diff=9523.241, P <0.01). The values recovered to preoperative levels at 3 months postoperatively and there was no statistically significant difference among the two groups. At 1 day, 7 days, 1 month and 3 months postoperatively, the mean subjective scores for dryness of the a clear cornea incision margin level group were higher than the clear cornea incision above margin group; and a statistically significant difference among the two groups (F group diff=6781.533, P <0.01). All of the values recovered to preoperative levels at 3 months postoperatively. \u0000 \u0000 \u0000Conclusions \u0000A clear cornea incision above margin phacoemulsification bring less disturbance to ocular surface, brighter symptoms of dry eye and the patients feel more comfortable. \u0000 \u0000 \u0000Key words: \u0000Microincision coaxial cataract surgery; A clear cornea incision above margin; A clear cornea incision margin level; Tear film; Dryness","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73140865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.010
Jingjing Sun, C. Jiang
Objective To study the changes of female patients’ mental health before and after excimer laser surgery. Methods Forty three female patients with refractive error admitted in Peking University People’s Hospital and treated with excimer laser surgery from July 21, 2014 to September 30, 2014 were selected in the study. Results The force, anxiety, terror and psychoticism factor scores of the patients preoperatively were higher than the norm (P <0.05), while the positive factor numbers were also more than the norm (P <0.05). The interpersonal sensitivity and paranoid factor scores postoperation were lower than the norm (P <0.05). Compared with the preoperative, after sur-gery the somatization, force, interpersonal sensitivity, depression, anxiety, hostility, terror, paranoia and psychoticism scores were significantly decreased (P <0.05), and the positive factor numbers were also decreased significantly than preoperative (P <0.05). Conclusions There are obvious mental health problems preoperatively of female excimer laser surgery patients. The problems could be alleviated much after surgery. Key words: Excimer laser surgery; Female; SCL-90
{"title":"A study on the changes of female patients’ mental health before and after excimer laser surgery","authors":"Jingjing Sun, C. Jiang","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.010","url":null,"abstract":"Objective \u0000To study the changes of female patients’ mental health before and after excimer laser surgery. \u0000 \u0000 \u0000Methods \u0000Forty three female patients with refractive error admitted in Peking University People’s Hospital and treated with excimer laser surgery from July 21, 2014 to September 30, 2014 were selected in the study. \u0000 \u0000 \u0000Results \u0000The force, anxiety, terror and psychoticism factor scores of the patients preoperatively were higher than the norm (P <0.05), while the positive factor numbers were also more than the norm (P <0.05). The interpersonal sensitivity and paranoid factor scores postoperation were lower than the norm (P <0.05). Compared with the preoperative, after sur-gery the somatization, force, interpersonal sensitivity, depression, anxiety, hostility, terror, paranoia and psychoticism scores were significantly decreased (P <0.05), and the positive factor numbers were also decreased significantly than preoperative (P <0.05). \u0000 \u0000 \u0000Conclusions \u0000There are obvious mental health problems preoperatively of female excimer laser surgery patients. The problems could be alleviated much after surgery. \u0000 \u0000 \u0000Key words: \u0000Excimer laser surgery; Female; SCL-90","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86780253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.016
Jianmei Yuan
Objective To analyze pathogens and outcomes of fifty-one eyeball evisceration. Methods The data of pathogens and outcomes of 51 inpatients (51 eyes) undergone eyeball evisceration were collected and analyzed from January 2000 to May 2015 retrospectively. Results Fifty-one eyes consisted of 18 eyeball atrophy, 14 serious lacerated wound, 9 secondary glaucoma, 6 corneal ulcers with perforation, 4 entophthalmia. Conclusions Evisceration associated with stage Ⅰ implantation not only can decrease exposed implants and narrow conjunctival saccus, but also can reduce reoperation pains and economic pressures. Key words: Evisceration; Pathogen; Outcome
{"title":"Pathogens and outcomes of fifty-one eyeball evisceration","authors":"Jianmei Yuan","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.016","url":null,"abstract":"Objective \u0000To analyze pathogens and outcomes of fifty-one eyeball evisceration. \u0000 \u0000 \u0000Methods \u0000The data of pathogens and outcomes of 51 inpatients (51 eyes) undergone eyeball evisceration were collected and analyzed from January 2000 to May 2015 retrospectively. \u0000 \u0000 \u0000Results \u0000Fifty-one eyes consisted of 18 eyeball atrophy, 14 serious lacerated wound, 9 secondary glaucoma, 6 corneal ulcers with perforation, 4 entophthalmia. \u0000 \u0000 \u0000Conclusions \u0000Evisceration associated with stage Ⅰ implantation not only can decrease exposed implants and narrow conjunctival saccus, but also can reduce reoperation pains and economic pressures. \u0000 \u0000 \u0000Key words: \u0000Evisceration; Pathogen; Outcome","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89740458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-10DOI: 10.3760/CMA.J.ISSN.1006-4443.2017.04.012
Xiayun Hu, Lina Zhang, Lifang Shen
Objective To evaluate the clinical effect of 25G pars plana vitrectomy with inner limiting membrane peeling and air tamponade for idiopathic macular hole (IMH). Methods Retrospectively examined 28 patients (28 eyes) with IMH in whom 25G vitrectomy, peeling of the inner limiting membrane underwent 0.25mg/ml brilliant blue G(BBG)-assisted, and application of sterile air tamponade were performed. The main observations were the surgical time, best corrected visual acuity (BCVA), intraocular pressure, the healing of macular hole and surgery complications. The follow-up period was 3-24 months (median 12.2±3.6 months). Results The operation lasted for 22-40minutes, meanly 28minutes, 28 cases were all successfully peeled of the inner limiting membrane, macular hole were closed in 28 eyes (100%), visual improvement was achieved in 21 eyes (75%), no eye was worse. The mean BCVA was 0.65±0.194 postoperatively, there was significant statistical differences compared with that before operation (t=13.768, P=0.000). The mean intraocular pressure at postoperative 1 week was (15.3±3.7) mmHg, closed to preoperative level. Eight eyes had punctate retinal hemorrhage when peeling of the inner limiting membrane, 4 eyes had nuclear cataract, 3 eyes had transient higher intraocular pressure, no other serious postoperative complications were observed during the follow-up time in all cases. Conclusions 25G vitrectomy with inner limiting membrane peeling and air tamponade is an effective and safe minimally invasive surgical technique, it can promote healing of macular hole, improve visual acuity, shorten operation time, decrease complication. Key words: 25G vitrectomy; Idiopathic macular hole; Inner limiting membrane peeling
{"title":"25G pars plana vitrectomy combined with peeling of the inner limiting membrane and air tamponade in idiopathic macular hole","authors":"Xiayun Hu, Lina Zhang, Lifang Shen","doi":"10.3760/CMA.J.ISSN.1006-4443.2017.04.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-4443.2017.04.012","url":null,"abstract":"Objective \u0000To evaluate the clinical effect of 25G pars plana vitrectomy with inner limiting membrane peeling and air tamponade for idiopathic macular hole (IMH). \u0000 \u0000 \u0000Methods \u0000Retrospectively examined 28 patients (28 eyes) with IMH in whom 25G vitrectomy, peeling of the inner limiting membrane underwent 0.25mg/ml brilliant blue G(BBG)-assisted, and application of sterile air tamponade were performed. The main observations were the surgical time, best corrected visual acuity (BCVA), intraocular pressure, the healing of macular hole and surgery complications. The follow-up period was 3-24 months (median 12.2±3.6 months). \u0000 \u0000 \u0000Results \u0000The operation lasted for 22-40minutes, meanly 28minutes, 28 cases were all successfully peeled of the inner limiting membrane, macular hole were closed in 28 eyes (100%), visual improvement was achieved in 21 eyes (75%), no eye was worse. The mean BCVA was 0.65±0.194 postoperatively, there was significant statistical differences compared with that before operation (t=13.768, P=0.000). The mean intraocular pressure at postoperative 1 week was (15.3±3.7) mmHg, closed to preoperative level. Eight eyes had punctate retinal hemorrhage when peeling of the inner limiting membrane, 4 eyes had nuclear cataract, 3 eyes had transient higher intraocular pressure, no other serious postoperative complications were observed during the follow-up time in all cases. \u0000 \u0000 \u0000Conclusions \u000025G vitrectomy with inner limiting membrane peeling and air tamponade is an effective and safe minimally invasive surgical technique, it can promote healing of macular hole, improve visual acuity, shorten operation time, decrease complication. \u0000 \u0000 \u0000Key words: \u000025G vitrectomy; Idiopathic macular hole; Inner limiting membrane peeling","PeriodicalId":10236,"journal":{"name":"Chinese Journal of Practical Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79069265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}